Most Recent Additions*

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Structure-based discovery of a small-molecule inhibitor of methicillin-resistant
Jie Liu, Lina Kozhaya, Victor J Torres, Derya Unutmaz, and Min Lu

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The Loss of TBK1 Kinase Activity in Motor Neurons or in All Cell Types Differentially Impacts ALS Disease Progression in SOD1 Mice.
Valeria Gerbino, Esther Kaunga, Junqiang Ye, Daniele Canzio, Sean O'Keeffe, Noam D Rudnick, Paolo Guarnieri, Cathleen Lutz, and Tom Maniatis

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Loss of CHD1 Promotes Heterogeneous Mechanisms of Resistance to AR-Targeted Therapy via Chromatin Dysregulation.
Zeda Zhang, Chuanli Zhou, Xiaoling Li, Spencer D Barnes, Su Deng, Elizabeth Hoover, Chi-Chao Chen, Young Sun Lee, Yanxiao Zhang, Choushi Wang, Lauren A Metang, Chao Wu, Carla Rodriguez Tirado, Nickolas A Johnson, John Wongvipat, Kristina Navrazhina, Zhen Cao, Danielle Choi, Chun-Hao Huang, Eliot Linton, Xiaoping Chen, Yupu Liang, Christopher E Mason, Elisa de Stanchina, Wassim Abida, Amaia Lujambio, Sheng Li, Scott W Lowe, Joshua T Mendell, Venkat S Malladi, Charles L Sawyers, and Ping Mu

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Precise Spatiotemporal Control of Nodal Na
Yael Eshed-Eisenbach, Jerome Devaux, Anna Vainshtein, Ofra Golani, Se-Jin Lee, Konstantin Feinberg, Natasha Sukhanov, Daniel S Greenspan, Keiichiro Susuki, Matthew N Rasband, and Elior Peles

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LDB1 Enforces Stability on Direct and Indirect Oncoprotein Partners in Leukemia.
Justin H Layer, Michael Christy, Lindsey Placek, Derya Unutmaz, Yan Guo, and Utpal P Davé

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Implications of increased S100β and Tau5 proteins in dystrophic nerves of two mdx mouse models for Duchenne muscular dystrophy.
Vidya S Krishnan, Annemieke Aartsma-Rus, Maurice Overzier, Cathleen Lutz, Laurent P. Bogdanik, and Miranda D Grounds

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High-throughput sleep phenotyping produces robust and heritable traits in Diversity Outbred mice and their founder strains.
Brendan T Keenan, Raymond J Galante, Jie Lian, Petr Simecek, Daniel M. Gatti, Lin Zhang, Diane C Lim, Karen L. Svenson, Gary Churchill, and Allan I Pack

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Nitrosative stress and lipid homeostasis as a mechanism for zileuton hepatotoxicity and resistance in genetically sensitive mice.
Dahea You, Lascelles E Lyn-Cook, Daniel M. Gatti, Natalie Bell, Philip R Mayeux, Laura P James, William B Mattes, Gary J Larson, and Alison H Harrill

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MSIsensor-pro: Fast, Accurate, and Matched-normal-sample-free Detection of Microsatellite Instability.
Peng Jia, Xiaofei Yang, Li Guo, Bowen Liu, Jiadong Lin, Hao Liang, Jianyong Sun, Chengsheng Zhang, and Kai Ye

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Loss of PRSS56 function leads to ocular angle defects and increased susceptibility to high intraocular pressure.
Cassandre Labelle-Dumais, Goutham Pyatla, Seyyedhassan Paylakhi, Nicholas G Tolman, Syed Hameed, Yusef Seymens, Eric Dang, Anil K Mandal, Sirisha Senthil, Rohit C Khanna, Meha Kabra, Inderjeet Kaur, Simon W M John, Subhabrata Chakrabarti, and K Saidas Nair

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Sestrins induce natural killer function in senescent-like CD8
Branca I Pereira, Roel P H De Maeyer, Luciana P Covre, Djamel Nehar-Belaid, Alessio Lanna, Sophie Ward, Radu Marches, Emma S Chambers, Daniel C O Gomes, Natalie E Riddell, Mala K Maini, Vitor H Teixeira, Samuel M Janes, Derek W Gilroy, Anis Larbi, Neil A Mabbott, Duygu Ucar, George A Kuchel, Sian M Henson, Jessica Strid, Jun H Lee, Jacques Banchereau, and Arne N Akbar

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Systematic Establishment of Robustness and Standards in Patient-Derived Xenograft Experiments and Analysis.
Yvonne A Evrard, Anuj Srivastava, Jelena Randjelovic, Nci PDXNet Consortium, James H Doroshow, Dennis A Dean, Jeffrey S Morris, and Jeffrey Chuang

 

Distinct mechanisms of dissemination of NDM-1 metallo- β-lactamase in
Mark D Adams, Fernando Pasteran, German M Traglia, Jasmine Martinez, Fanny Huang, Christine Liu, Jennifer S Fernandez, Carolina Lopez, Lisandro J Gonzalez, Ezequiel Albornoz, Alejandra Corso, Alejandro J Vila, Robert A Bonomo, and Maria Soledad Ramirez

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Disruption in murine Eml1 perturbs retinal lamination during early development.
Gayle B. Collin, J Won, Mark P. Krebs, W J Hicks, Jeremy R. Charette, Juergen K. Naggert, and Patsy M. Nishina

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miR-181a Modulation of ERK-MAPK Signaling Sustains DC-SIGN Expression and Limits Activation of Monocyte-Derived Dendritic Cells.
Clarice X Lim, Bernett Lee, Olivia Geiger, Christina Passegger, Michaela Beitzinger, Johann Romberger, Anika Stracke, Christoph Högenauer, Anton Stift, Heribert Stoiber, Michael Poidinger, Armin Zebisch, Gunter Meister, Adam Williams, Richard A Flavell, Jorge Henao-Mejia, and Herbert Strobl

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Techniques for the generation of humanized mouse models for immuno-oncology.
Chun I. Yu, Florentina Marches, Te-Chia Wu, Jan Martinek, and Karolina Palucka

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Molecular profiling of gynecologic cancers for treatment and management of disease - demonstrating clinical significance using the AMP/ASCO/CAP guidelines for interpretation and reporting of somatic variants.
Qian Nie, Gregory Omerza, Harshpreet Chandok, Matthew Prego, Meng-Chang Hsiao, Bridgette Meyers, Andrew N Hesse, Jasmina Uvalic, Melissa Soucy, Daniel Bergeron, Michael Peracchio, Shelbi Burns, Kevin Kelly, Shannon Rowe, Jens Rueter, and Honey V Reddi

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Molecular Evolution of IDH Wild-Type Glioblastomas Treated With Standard of Care Affects Survival and Design of Precision Medicine Trials: A Report From the EORTC 1542 Study.
Kaspar Draaisma, Aikaterini Chatzipli, Martin Taphoorn, Melissa Kerkhof, Astrid Weyerbrock, Marc Sanson, Ann Hoeben, Slávka Lukacova, Giuseppe Lombardi, Sieger Leenstra, Monique Hanse, Ruth Fleischeuer, Colin Watts, Joseph McAbee, Nicos Angelopoulos, Thierry Gorlia, Vassilis Golfinopoulos, Johan M Kros, Roel G W Verhaak, Vincent Bours, Martin J van den Bent, Ultan McDermott, Pierre A Robe, and Pim J French

*Updated as of 04/10/20.