Most Recent Additions*

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Opportunities, resources, and techniques for implementing genomics in clinical care.
Teri A Manolio, Robb Rowley, Marc S Williams, Dan Roden, Geoffrey S Ginsburg, Carol J Bult, Rex L Chisholm, Patricia A Deverka, Howard L McLeod, George A Mensah, Mary V Relling, Laura Lyman Rodriguez, Cecelia Tamburro, and Eric D Green

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The RNA-binding protein DND1 acts sequentially as a negative regulator of pluripotency and a positive regulator of epigenetic modifiers required for germ cell reprogramming.
Victor A Ruthig, Matthew B Friedersdorf, Jason A Garness, Steven C. Munger, Corey Bunce, Jack D Keene, and Blanche Capel

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Doxorubicin-Induced Cardiotoxicity in Collaborative Cross (CC) Mice Recapitulates Individual Cardiotoxicity in Humans.
Caroline J Zeiss, Daniel M Gatti, Olga Toro-Salazar, Crystal Davis, Cathleen M Lutz, Francis Spinale, Timothy M Stearns, Milena B Furtado, and Gary A Churchill

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Cyfip1 Haploinsufficiency Increases Compulsive-Like Behavior and Modulates Palatable Food Intake in Mice: Dependence on Cyfip2 Genetic Background, Parent-of Origin, and Sex.
Richard K Babbs, Jacob A Beierle, Qiu T Ruan, Julia C Kelliher, Melanie M Chen, Ashley X Feng, Stacey L Kirkpatrick, Fabiola A Benitez, Fred A Rodriguez, Johanne J Pierre, Jeya Anandakumar, Vivek Kumar, Megan K Mulligan, and Camron D Bryant

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Characterization of acute TLR-7 agonist-induced hemorrhagic myocarditis in mice by multi-parametric quantitative cardiac MRI.
Nicoleta Baxan, Angelos Papanikolaou, Isabelle Salles-Crawley, Amrit Lota, Rasheda Chowdhury, Olivier Dubois, Jane Branca, Muneer G. Hasham, Nadia Rosenthal, Sanjay K Prasad, Lan Zhao, Sian E Harding, and Susanne Sattler

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Differential effects of rapamycin on glucose metabolism in 9 inbred strains.
Peter C. Reifsnyder, Austen Te, and David E Harrison

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Microbiome Signatures Associated with Steatohepatitis and Moderate to Severe Fibrosis in Children With Nonalcoholic Fatty Liver Disease.
Jeffrey B Schwimmer, Jethro S Johnson, Jorge E Angeles, Cynthia Behling, Patricia H Belt, Ingrid Borecki, Craig Bross, Janis Durelle, Nidhi P Goyal, Gavin Hamilton, Mary L Holtz, Joel E Lavine, Makedonka Mitreva, Kimberly P Newton, Amy Pan, Pippa M Simpson, Claude B Sirlin, Erica Sodergren, Rahul Tyagi, Katherine P Yates, George M. Weinstock, and Nita H Salzman

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Detection and Classification of Novel Renal Histologic Phenotypes Using Deep Neural Networks.
Susan Sheehan, Seamus Mawe, Rachel E Cianciolo, Ron Korstanje, and J Matthew Mahoney

 

2-deoxy D-glucose treatment does not elicit a hair growth response in alopecia areata.
John P Sundberg, Kathleen A Silva, Victoria E. Kennedy, John J Wilson, Nicholas E Gott, Beth A. Sundberg, and Derry C. Roopenian

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Gain of function p.E138A alteration in Card14 leads to psoriasiform skin inflammation and implicates genetic modifiers in disease severity.
John P Sundberg, C Herbert Pratt, Kathleen A Silva, Victoria E. Kennedy, Wenning Qin, Timothy M Stearns, Jacqueline Frost, Beth A. Sundberg, and Anne M Bowcock

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AK002, a Humanized Sialic Acid-Binding Immunoglobulin-Like Lectin-8 Antibody that Induces Antibody-Dependent Cell-Mediated Cytotoxicity against Human Eosinophils and Inhibits Mast Cell-Mediated Anaphylaxis in Mice.
Bradford A Youngblood, Emily C Brock, John Leung, Rustom Falahati, Paul J Bryce, Jessica Bright, Jason Williams, Leonard D. Shultz, Dale L Greiner, Michael A Brehm, Christopher Bebbington, and Nenad Tomasevic

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Rapid growth is a dominant predictor of hepcidin suppression and declining ferritin in Gambian infants.
Andrew E Armitage, Schadrac C Agbla, Modupeh Betts, Ebrima A Sise, Momodou W Jallow, Ellen Sambou, Bakary Darboe, Archibald Worwui, George M. Weinstock, Martin Antonio, Sant-Rayn Pasricha, Andrew M Prentice, Hal Drakesmith, Momodou K Darboe, and Brenda Anna Kwambana-Adams

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Cross-Species Single-Cell Analysis of Pancreatic Ductal Adenocarcinoma Reveals Antigen-Presenting Cancer-Associated Fibroblasts.
Ela Elyada, Mohan Bolisetty, Pasquale Laise, William F Flynn, Elise T Courtois, Richard A Burkhart, Jonathan A Teinor, Pascal Belleau, Giulia Biffi, Matthew S Lucito, Santhosh Sivajothi, Todd D Armstrong, Dannielle D Engle, Kenneth H Yu, Yuan Hao, Christopher L Wolfgang, Youngkyu Park, Jonathan Preall, Elizabeth M Jaffee, Andrea Califano, Paul Robson, and David A Tuveson

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Functional rescue in a mouse model of congenital muscular dystrophy with megaconial myopathy.
Ambreen A Sayed-Zahid, Roger B Sher, Stacey J Sukoff Rizzo, Laura C. Anderson, Kathryn E Patenaude, and Gregory A. Cox

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Improving homology-directed repair efficiency in human stem cells.
William C Skarnes, Enrica Pellegrino, and Justin A McDonough

 

Genetic background modifies CNS-mediated sensorimotor decline in the AD-BXD mouse model of genetic diversity in Alzheimer's disease.
Kristen M S O'Connell, Andrew R Ouellette, Sarah M Neuner, Amy R Dunn, and Catherine Kaczorowski

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Identification of a T follicular helper cell subset that drives anaphylactic IgE.
Uthaman Gowthaman, Jennifer S Chen, Biyan Zhang, William F Flynn, Yisi Lu, Wenzhi Song, Julie Joseph, Jake A Gertie, Lan Xu, Magalie A Collet, Jessica D S Grassmann, Tregony Simoneau, David Chiang, M Cecilia Berin, Joseph E Craft, Jason S Weinstein, Adam Williams, and Stephanie C Eisenbarth

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Meox2 Haploinsufficiency Accelerates Axonal Degeneration in DBA/2J Glaucoma.
Rebecca A Buchanan, Kate E Foley, Keating W. Pepper, Alaina M Reagan, Kelly J Keezer, Amanda A Hewes, Cory A Diemler, Christoph Preuss, Ileana Soto, Simon W M John, and Gareth R Howell

 

Genetic mapping in Diversity Outbred mice identifies a Trpa1 variant influencing late-phase formalin response.
Jill M. Recla, Jason A. Bubier, Daniel M Gatti, Jennifer L Ryan, Katie H Long, Raymond F. Robledo, Nicole C Glidden, Guoqiang Hou, Gary Churchill, Richard S. Maser, Zhong-Wei Zhang, Erin E Young, Elissa J Chesler, and Carol J Bult

*Updated as of 08/23/19.