Faculty Research 1970 - 1979
Genetics of mouse antibodies. I. Linkage of the dextran response locus, VH-DEX, to allotype.
Document Type
Article
Publication Date
1975
Keywords
Antibodies: ge, Binding-Sites-Antibody: ge, Chromosome-Mapping, Crosses-Genetic, Dextrans: im, Immunoglobulin-Allotypes, Immunoglobulin-Variable-Region: ge, Immunoglobulins-Heavy-Chain, Linkage-(Genetics), Mice, Mice-Inbred-AKR, Mice-Inbred-BALB-C, Mice-Inbred-C3H, Mice-Inbred-C57BL, Recombination-Genetic, SUPPORT-U-S-GOVT-P-H-S
First Page
775
Last Page
777
JAX Source
Eur-J-Immunol. 1975 Nov; 5(11):775-7.
Abstract
The antibody response of mice to alpha-1,3 linked dextran is shown to be controlled by a heavy chain variable region gene, VH-DEX. The map distance between this gene and the heavy chain allotype locus is estimated to be 0.3 recombination units.
Recommended Citation
Riblet R,
Blomberg B,
Weigert M,
Lieberman R,
Taylor BA,
Potter M.
Genetics of mouse antibodies. I. Linkage of the dextran response locus, VH-DEX, to allotype. Eur-J-Immunol. 1975 Nov; 5(11):775-7.