Transmissible murine colonic hyperplasia.

Authors

S W. Barthold
G L. Coleman
R O. Jacoby
E M. Livestone
A M. Jonas

Document Type

Article

Publication Date

1978

Keywords

Citrobacter, Colitis: pa, ve, Colon: pa, Colonic-Diseases: pa, ve, Comparative-Study, Enterobacteriaceae-Infections: pa, ve, Female, Hyperplasia, Intestinal-Mucosa: pa, Male, Mice, Rodent-Diseases: pa, SUPPORT-U-S-GOVT-P-H-S

First Page

223

Last Page

236

JAX Source

Vet-Pathol. 1978 Mar; 15(2):223-36.

Abstract

After exposure to a variant of Citrobacter freundii, suckling and adult mice developed transmissible murine colonic hyperplasia of the same degree of severity. Mucosal hyperplasia was most severe 2 to 3 weeks after inoculation and then regressed. Suckling mice had a high mortality because of secondary inflammatory and erosive changes. Severe hyperplasia was characterized by mitotic activity along the entire crypt column and surface mucosa.

Recommended Citation

Barthold SW, Coleman GL, Jacoby RO, Livestone EM, Jonas AM. Transmissible murine colonic hyperplasia. Vet-Pathol. 1978 Mar; 15(2):223-36.