Marked reduction of spectrinin hereditary spherocytosis in the common house mouse.
Electrophoresis-Polyacrylamide-Gel, Erythrocyte-Membrane, Membrane-Proteins: df, Mice, Peptides, Spectrin: df, Spherocytes, Spherocytosis-Hereditary: bl, fg, SUPPORT-U-S-GOVT-P-H-S
Blood. 1978 Jun; 51(6):1149-55.
In contrast to the disease in humans, hereditary spherocytosis in the common house mouse produces an extreme spherocytosis. The cells show a broad distribution in size ranging from microcytic to macrocytic. Of particular interest is the finding of a substantial reduction in the major membrane polypeptide called spectrin, supporting a critical role for this protein in the control of erythrocyte shape and membrane stability.
Greenquist, A C.; Shohet, S B.; and Bernstein, S E., " Marked reduction of spectrinin hereditary spherocytosis in the common house mouse." (1978). Faculty Research 1970 - 1979. 901.
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