Visualization of omics data for systems biology.
Document Type
Article
Publication Date
2010
Keywords
Image-Processing-Computer-Assisted, Mass-Spectrometry, Metabolomics, Nuclear-Magnetic-Resonance-Biomolecular, Protein-Binding, Proteomics, Systems-Biology
JAX Source
Nat Methods 2010 Mar; 7(suppl):S56-68.
Abstract
High-throughput studies of biological systems are rapidly accumulating a wealth of 'omics'-scale data. Visualization is a key aspect of both the analysis and understanding of these data, and users now have many visualization methods and tools to choose from. The challenge is to create clear, meaningful and integrated visualizations that give biological insight, without being overwhelmed by the intrinsic complexity of the data. In this review, we discuss how visualization tools are being used to help interpret protein interaction, gene expression and metabolic profile data, and we highlight emerging new directions.
Recommended Citation
Gehlenborg N,
O'Donoghue SI,
Hibbs MA,
Kitano H,
Kohlbacher O,
Neuweger H,
Tenenbaum D.
Visualization of omics data for systems biology. Nat Methods 2010 Mar; 7(suppl):S56-68.