Submissions from 2010
Mouse BMD quantitative trait loci show improved concordance with human genome-wide association loci when recalculated on a new, common mouse genetic map., Bicknell C. Ackert, D Karasik, Q Li, R V. Smith, Y H. Hsu, G A. Churchill, B J. Paigen, and S W. Tsaih
Ontology engineering., G Alterovitz, D P. Hill, J Lomax, C Mungall, M A. Harris, M E. Dolan, J A. Blake, and al et
Measurement of replication structures at the nanometer scale using super-resolution light microscopy., D Baddeley, V O. Chagin, L Schermelleh, S Martin, A Pombo, P M. Carlton, A Gahl, P Domaing, U Birk, H Leonhardt, C Cremer, and M C. Cardoso
Model based precision structural measurements on barely resolved objects., D Baddeley, Y Weiland, C Batram, U Birk, and C Cremer
Beta-endorphin mediates behavioral despair and the effect of ethanol on the tail suspension test in mice., E T. Barfield, S M. Barry, H B. Hodgin, B M. Thompson, S S. Allen, and J E. Grisel
Quantitative analysis of fitness and genetic interactions in yeast on a genome scale., A Baryshnikova, M Costanzo, J Koh, K Toufighi, J Y. Youn, M Hibbs, D Hess, A C. Gingras, and al et
Patterns of recombination activity on mouse chromosome 11 revealed by high resolution mapping., T Billings, E E. Sargent, J P. Szatkiewicz, N Leahy, I Y. Kwak, N Bektassova, M Walker, T Hassold, J H. Graber, K W. Broman, and P M. Petkov
Cdcs1 a major colitis susceptibility locus in mice; subcongenic analysis reveals genetic complexity., A Bleich, G Buchler, J P. Affourtit, B L. King, D J. Shaffer, D C. Roopenian, H J. Hedrich, J P. Sundberg, and E H. Leiter
Male mice not alone in research., B Bolon, S W. Barthold, K L. Boyd, C Brayton, R D. Cardiff, L C. Cork, K A. Eaton, T R. Schoeb, J P. Sundberg, and J M. Ward
New candidate genes identified for controlling mouse gonadal sex determination and the early stages of granulosa and Sertoli cell differentiation., G J. Bouma, Q J. Hudson, L L. Washburn, and E M. Eicher
A missense mutation in a highly conserved alternate exon of dynamin-1 causes epilepsy in fitful mice., R M. Boumil, V A. Letts, M C. Roberts, C Lenz, C L. Mahaffey, Z W. Zhang, T Moser, and W N. Frankel
Parameters for establishing humanized mouse models to study human immunity: analysis of human hematopoietic stem cell engraftment in three immunodeficient strains of mice bearing the IL2rgamma(null) mutation., M A. Brehm, A Cuthbert, C Yang, D M. Miller, P DiIorio, J Laning, L Burzenski, B Gott, O Foreman, A Kavirayani, M Herlihy, A A. Rossini, L D. Shultz, and D L. Greiner
Human immune system development and rejection of human islet allografts in spontaneously diabetic NOD-Rag1null IL2rgammanull Ins2Akita mice., M A. Brehm, J Laning, A Cuthbert, C Yang, M Herlihy, L Burzenski, B Gott, O Foreman, A C. Powers, D L. Greiner, and L D. Shultz
Humanized mouse models to study human diseases., M A. Brehm, L D. Shultz, and D L. Greiner
A mouse model of generalized non-Herlitz junctional epidermolysis bullosa., J A. Bubier, T J. Sproule, L M. Alley, C M. Webb, J D. Fine, D C. Roopenian, and J P. Sundberg
Mutations of the opsin gene (Y102H and I307N) lead to light-induced degeneration of photoreceptors and constitutive activation of phototransduction in mice., E Budzynski, A K. Gross, S D. McAlear, M Edwards, J Won, W L. Hicks, T G. Wensel, J K. Naggert, and P M. Nishina
The Mouse Genome Database: enhancements and updates., C J. Bult, J A. Kadin, J E. Richardson, J A. Blake, J T. Eppig, and Genome Database Mouse
Neuromuscular disease models and analysis., R W. Burgess, G A. Cox, and K L. Seburn
Nephroblastoma overexpressed (Nov) inactivation sensitizes osteoblasts to bone morphogenetic protein-2, but nov is dispensable for skeletal homeostasis., E Canalis, Ramoya A. Smerdel, D Durant, A N. Economides, W G. Beamer, and S Zanotti
Connective tissue growth factor is required for skeletal development and postnatal skeletal homeostasis in male mice., E Canalis, S Zanotti, W G. Beamer, A N. Economides, and Ramoya A. Smerdel
Connective tissue growth factor is required for skeletal development and postnatal skeletal homeostasis in male mice., E Canalis, S Zanotti, W G. Beamer, A N. Economides, and Ramoya A. Smerdel
Nerve terminal degeneration is independent of muscle fiber genotype in SOD1 mice., D I. Carrasco, E K. Bichler, K L. Seburn, and M J. Pinter
A systems-biology approach to modular genetic complexity., G W. Carter, C G. Rush, F Uygun, N A. Sakhanenko, D J. Galas, and T Galitski
Segregation analysis of a sex ratio distortion locus in congenic mice., J Casellas, C R. Farber, R A. Verdugo, and J F. Medrano
The mouse mutation "thrombocytopenia and cardiomyopathy" (trac) disrupts Abcg5: a spontaneous single gene model for human hereditary phytosterolemia/sitosterolemia., T H. Chase, B L. Lyons, R T. Bronson, O Foreman, L R. Donahue, L M. Burzenski, B Gott, P Lane, B Harris, K R. Johnson, and L D. Shultz
The importance of open-source integrative genomics to drug discovery., E J. Chesler and E J. Baker
Sub-cubic millimeter intraocular pressure monitoring implant to enable genetic studies on pressure-induced neurodegeneration., E Y. Chow, D Ha, T Y. Lin, W N. Devries, S W. John, W J. Chappell, and P P. Irazoqui
A historical perspective on leptin., D L. Coleman
Behavioral validation of the Ts65Dn mouse model for Down syndrome of a genetic background free of the retinal degeneration mutation Pde6b(rd1)., A C. Costa, M R. Stasko, C Schmidt, and M T. Davisson
Combining QTL data for HDL cholesterol levels from two different species leads to smaller confidence intervals., A Cox, S M. Sheehan, I Kloting, B Paigen, and R Korstanje
Occupational mouse allergen exposure among non-mouse handlers., Brosnan J. Curtin, B Paigen, K A. Hagberg, S Langley, E A. O'Neil, M Krevans, P A. Eggleston, and E C. Matsui
A novel spontaneous mutation of Irs1 in mice results in hyperinsulinemia, reduced growth, low bone mass and impaired adipogenesis., V E. DeMambro, M Kawai, T L. Clemens, K Fulzele, J A. Maynard, d e. Marin, K R. Johnson, E Canalis, W G. Beamer, C J. Rosen, and L R. Donahue
Cancer genomes., E P. Diamandis, T Hudson, O Kallioniemi, E T. Liu, and Otin C. Lopez
4Pi microscopy reveals an impaired three-dimensional mitochondrial network of pancreatic islet beta-cells, an experimental model of type-2 diabetes., A Dlaskova, T Spacek, J Santorova, Hlavata L. Plecita, Z Berkova, F Saudek, M Lessard, J Bewersdorf, and P Jezek
JAX Colony Management System (JCMS): an extensible colony and phenotype data management system., C J. Donnelly, M McFarland, A Ames, B Sundberg, D Springer, P Blauth, and C J. Bult
Invariant natural killer T-cell control of type 1 diabetes: a dendritic cell genetic decision of a silver bullet or Russian roulette., J P. Driver, F Scheuplein, Y G. Chen, A E. Grier, S B. Wilson, and D V. Serreze
Anti-CD4-targeted gold nanoparticles induce specific contrast enhancement of peripheral lymph nodes in X-ray computed tomography of live mice., W Eck, A I. Nicholson, H Zentgraf, W Semmler, and S Bartling
Mutations in Lama1 disrupt retinal vascular development and inner limiting membrane formation., Malia M. Edwards, Elmina Mammadova-Bach, Fabien Alpy, Annick Klein, Wanda L. Hicks, Michel Roux, Patricia Simon-Assmann, Richard S. Smith, Gertraud Orend, Jiang Wu, Neal S. Peachey, Jurgen K. Naggert, Olivier Lefebvre, and Patsy M. Nishina
Photoreceptor degeneration, azoospermia, leukoencephalopathy, and abnormal RPE cell function in mice expressing an early stop mutation in CLCN2., M M. Edwards, de Evsikova Marin, G B. Collin, E Gifford, J Wu, N Maphis, B T. Lamb, J K. Naggert, P M. Nishina, and N S. Peachey
Preadipocyte factor-1 is associated with marrow adiposity and bone mineral density in women with anorexia nervosa., P K. Fazeli, M A. Bredella, M Misra, E Meenaghan, C J. Rosen, D R. Clemmons, A Breggia, K K. Miller, and A Klibanski
Patent ductus arteriosus in mice with smooth muscle-specific Jag1 deletion., X Feng, L T. Krebs, and T Gridley
alpha- and beta-Adducin polymorphisms affect podocyte proteins and proteinuria in rodents and decline of renal function in human IgA nephropathy., M Ferrandi, D Cusi, I Molinari, F Macciardi, C Marcantoni, D Roccatello, L L. Peters, S Armelloni, and al et
Introduction to laboratory animal genetics., M F. Festing
Expression of the transcription factor, TFII-I, during post-implantation mouse embryonic development., I Fijalkowska, D Sharma, C J. Bult, and S K. Danoff
Generation of a conditional null allele of NADPH oxidase activator 1 (NOXA1)., J P. Flaherty, C A. Spruce, H E. Fairfield, and D E. Bergstrom
Is the filaggrin-histidine-urocanic acid pathway essential for stratum corneum acidification?, J W. Fluhr, P M. Elias, M Q. Man, M Hupe, C Selden, J P. Sundberg, E Tschachler, L Eckhart, T M. Mauro, and K R. Feingold
Life extension by diet restriction and N-acetyl-L-cysteine in genetically heterogeneous mice., K Flurkey, C M. Astle, and D E. Harrison
Reproductive ageing: Of worms and women., K Flurkey and D E. Harrison
Altered metabolism and lipodystrophy in the early B-cell factor 1-deficient mouse., J A. Fretz, T Nelson, Y Xi, D J. Adams, C J. Rosen, and M C. Horowitz
Loss of lysophosphatidylcholine acyltransferase 1 leads to photoreceptor degeneration in rd11 mice., J S. Friedman, B Chang, D S. Krauth, I Lopez, C Liu, S S. Bhattacharya, R K. Koenekoop, J R. Heckenlively, and al et
The insulin-like growth factor-1 binding protein acid-labile subunit alters mesenchymal stromal cell fate., J C. Fritton, Y Kawashima, W Mejia, H W. Courtland, S Elis, Y Wu, C J. Rosen, D Clemmons, and S Yakar
A novel null allele of mouse DSCAM survives to adulthood on an inbred C3H background with reduced phenotypic variability., P G. Fuerst, B S. Harris, K R. Johnson, and R W. Burgess
Integrating human and rodent data to identify the genetic factors involved in chronic kidney disease., M R. Garrett, M G. Pezzolesi, and R Korstanje
Sex-specific gene expression in the BXD mouse liver., D M. Gatti, N Zhao, E J. Chesler, B U. Bradford, A A. Shabalin, R Yordanova, L Lu, and I Rusyn
Visualization of omics data for systems biology., N Gehlenborg, S I. O'Donoghue, M A. Hibbs, H Kitano, O Kohlbacher, H Neuweger, and D Tenenbaum
The Gene Ontology in 2010: extensions and refinements., Ontology Consortium Gene
Molecular and phenotypic reassessment of an infrequently used mouse model for spinal muscular atrophy., R G. Gogliotti, S M. Hammond, C Lutz, and C J. Didonato
Pyrosequencing enhancement for better detection limit and sequencing homopolymers., M Gong, S H. Foo, L Lin, E T. Liu, B Gharizadeh, and S Goel
Nrk2b-mediated NAD+ production regulates cell adhesion and is required for muscle morphogenesis in vivo: Nrk2b and NAD+ in muscle morphogenesis., M F. Goody, M W. Kelly, K N. Lessard, A Khalil, and C A. Henry
In vivo selection of human embryonic stem cell-derived cells expressing methotrexate-resistant dihydrofolate reductase., J L. Gori, X Tian, D Swanson, R Gunther, L D. Shultz, R S. McIvor, and D S. Kaufman
Notch signaling in the vasculature., T Gridley
Functional genomics complements quantitative genetics in identifying disease-gene associations., Y Guan, Bicknell C. Ackert, B Kell, O G. Troyanskaya, and M A. Hibbs
High-fat diet leads to tissue-specific changes reflecting risk factors for diseases in DBA/2J mice., R S. Hageman, A Wagener, C Hantschel, K L. Svenson, G A. Churchill, and G A. Brockmann
Genetics of mammalian meiosis: regulation, dynamics and impact on fertility., M A. Handel and J C. Schimenti
Widespread genomic breaks generated by activation-induced cytidine deaminase are prevented by homologous recombination., M G. Hasham, N M. Donghia, E Coffey, J Maynard, K J. Snow, J Ames, R Y. Wilpan, Y He, B L. King, and K D. Mills
The waved with open eyelids (woe) locus is a hypomorphic mouse mutation in Adam17., E L. Hassemer, Gall S. Le, R Liegel, M McNally, B Chang, C J. Zeiss, R D. Dubielzig, K Horiuchi, T Kimura, Y Okada, C P. Blobel, and D J. Sidjanin
Representing ontogeny through ontology: a developmental biologist's guide to the gene ontology., D P. Hill, T Z. Berardini, D G. Howe, and Auken K. Van
A MOD(ern) perspective on literature curation., J Hirschman, T Z. Berardini, H J. Drabkin, and D Howe
ZFP191 is required by oligodendrocytes for CNS myelination., S Y. Howng, R L. Avila, B Emery, M Traka, W Lin, T Watkins, S Cook, R Bronson, M Davisson, B A. Barres, and B Popko
Development of a mouse model for sporadic and metastatic colon tumors and its use in assessing drug treatment., K E. Hung, M A. Maricevich, L G. Richard, W Y. Chen, M P. Richardson, A Kunin, R T. Bronson, U Mahmood, and R Kucherlapati
The de-ubiquitinase UCH-L1 is an oncogene that drives the development of lymphoma in vivo by deregulating PHLPP1 and Akt signaling., S Hussain, O Foreman, S L. Perkins, T E. Witzig, R R. Miles, Deursen J. van, and P J. Galardy
CGDSNPdb: a database resource for error-checked and imputed mouse SNPs., L N. Hutchins, Y Ding, J P. Szatkiewicz, Smith R. Von, H Yang, Villena F. de, G A. Churchill, and J H. Graber
An international bioinformatics infrastructure to underpin the Arabidopsis community., International Arabidopis Informatics Consortium
Oncogenic activation of the Notch1 gene by deletion of its promoter in Ikaros-deficient T-ALL., R Jeannet, J Mastio, T Ashworth, J Ghysdael, T Gridley, T Honjo, S Chan, and al et
Quantitative trait loci for tibial bone strength in C57BL/6J and C3H/HeJ inbred strains of mice., F Jiao, H Chiu, Y Jiao, Rijk W. de, X Li, E C. Eckstein, W G. Beamer, and W Gu
Mesenchymal cell remodeling during mouse secondary palate reorientation., J Z. Jin, M Tan, D R. Warner, D S. Darling, Y Higashi, T Gridley, and J Ding
Separate and combined effects of Sod1 and Cdh23 mutations on age-related hearing loss and cochlear pathology in C57BL/6J mice., K R. Johnson, H Yu, D Ding, H Jiang, L H. Gagnon, and R J. Salvi
Quantitative lymphatic vessel trait analysis suggests Vcam1 as candidate modifier gene of inflammatory bowel disease., G Jurisic, J P. Sundberg, A Bleich, E H. Leiter, K W. Broman, G Buechler, L Alley, D Vestweber, and M Detmar
Novel sequence feature variant type analysis of the HLA genetic association in systemic sclerosis., D R. Karp, N Marthandan, S G. Marsh, C Ahn, A D. Diehl, M Feolo, G Thomson, M J. Waller, and al et
Retrospective study of spontaneous osteosarcomas in the nonobese diabetic strain and nonobese diabetic-derived substrains of mice., A M. Kavirayani and O Foreman
Nocturnin: a circadian target of Pparg-induced adipogenesis., M Kawai, C B. Green, M Horowitz, Bicknell C. Ackert, Czernik B. Lecka, and C J. Rosen
A circadian-regulated gene, Nocturnin, promotes adipogenesis by stimulating PPAR-gamma nuclear translocation., M Kawai, C B. Green, Czernik B. Lecka, N Douris, M R. Gilbert, S Kojima, Bicknell C. Ackert, N Garg, M C. Horowitz, M L. Adamo, D R. Clemmons, and C J. Rosen
Bone: adiposity and bone accrual-still an established paradigm?, M Kawai and C J. Rosen
The Archon Genomics X PRIZE for whole human genome sequencing., L Kedes and E T. Liu
Gene-specific RNA polymerase II phosphorylation and the CTD code., H Kim, B Erickson, W Luo, D Seward, J H. Graber, D D. Pollock, P C. Megee, and D L. Bentley
Fine mapping in 94 inbred mouse strains using a high-density haplotype resource., A Kirby, H M. Kang, C M. Wade, C Cotsapas, E Y. Kang, M Rivas, M A. Bogue, K A. Frazer, and al et
p53 controls radiation-induced gastrointestinal syndrome in mice independent of apoptosis., D G. Kirsch, P M. Santiago, Tomaso E. di, J M. Sullivan, O Takeuchi, S J. Korsmeyer, R T. Bronson, C F. Kim, K M. Haigis, R K. Jain, and al et
Protein 4.2 binds to the carboxyl-terminal EF-hands of erythroid alpha-spectrin in a calcium- and calmodulin-dependent manner., C Korsgren, L L. Peters, and S E. Lux
Notch1 activation in mice causes arteriovenous malformations phenocopied by ephrinB2 and EphB4 mutants., L T. Krebs, C Starling, A V. Chervonsky, and T Gridley
An Msh2 conditional knockout mouse for studying intestinal cancer and testing anticancer agents., M H. Kucherlapati, K Lee, A A. Nguyen, A B. Clark, M Lipkin, R T. Bronson, T A. Kunkel, R Kucherlapati, and al et
Identification of genetic determinants of IGF-1 levels and longevity among mouse inbred strains., M S. Leduc, R S. Hageman, Q Meng, R A. Verdugo, S W. Tsaih, G A. Churchill, B Paigen, and R Yuan
A survey of airway responsiveness in 36 inbred mouse strains facilitates gene mapping studies and identification of quantitative trait loci., A S. Leme, A Berndt, L K. Williams, S W. Tsaih, J P. Szatkiewicz, R Verdugo, B Paigen, and S D. Shapiro
Humanized nonobese diabetic-scid IL2rgammanull mice are susceptible to lethal Salmonella Typhi infection., S J. Libby, M A. Brehm, D L. Greiner, L D. Shultz, M McClelland, K D. Smith, L A. Cummings, and al et
Epistasis contributes to the genetic buffering of plasma HDL cholesterol in mice., R H. Li and G A. Churchill
Q&A: ChIP-seq technologies and the study of gene regulation., E T. Liu, S Pott, and M Huss
miR-22 functions as a micro-oncogene in transformed human bronchial epithelial cells induced by anti-benzo[a]pyrene-7,8-diol-9,10-epoxide., L Liu, Y Jiang, H Zhang, A R. Greenlee, R Yu, and Q Yang
Molecular basis for hair loss in mice carrying a novel nonsense mutation (Hrrh-R ) in the hairless gene (Hr)., Y Liu, J P. Sundberg, S Das, D Carpenter, K T. Cain, E J. Michaud, and B H. Voy
Genetic dependence of central corneal thickness among inbred strains of mice., G D. Lively, B Jiang, Buenz A. Hedberg, B Chang, G E. Petersen, K Wang, M H. Kuehn, and M G. Anderson
Critical reasoning on causal inference in genome-wide linkage and association studies., Y Li, B M. Tesson, G A. Churchill, and R C. Jansen
Multi-variant pathway association analysis reveals the importance of genetic determinants of estrogen metabolism in breast and endometrial cancer susceptibility., Y L. Low, Y Li, K Humphreys, A Thalamuthu, Y Li, H Darabi, S Wedren, C Bonnard, K Czene, M M. Iles, T Heikkinen, K Aittomaki, C Blomqvist, H Nevanlinna, P Hall, E T. Liu, and J Liu