Cicatricial Alopecia Research Foundation meeting, May 2016: Progress towards the diagnosis, treatment and cure of primary cicatricial alopecias.
Document Type
Article
Publication Date
3-2018
JAX Location
Reprint Collection
JAX Source
Exp Dermatol 2018 Mar; 27(3):302-310.
Volume
27
Issue
3
First Page
302
Last Page
310
ISSN
1600-0625
PMID
29341265
DOI
https://doi.org/10.1111/exd.13495
Grant
Cicatricial Alopecia Research Foundation
Abstract
Primary cicatricial alopecias (PCAs) are a group of skin diseases in which there is progressive and permanent destruction of hair follicles followed by replacement with fibrous tissue. Unfortunately, by the time patients seek clinical evaluation of their hair loss, the skin is already inflamed and/or scarred, so there is little hope for a return to their normal hair growth pattern. Clinical and basic science investigations are now focusing on three forms of human PCA: lichen planopilaris (LPP), frontal fibrosing alopecia (FFA) and central centrifugal cicatricial alopecia (CCCA). Transcriptome, lipidome and other new technologies are providing new insight into the pathogenesis of some of these diseases that are being validated and further investigated using spontaneous and genetically engineered mouse models. Exp Dermatol 2018 Mar; 27(3):302-310.
Recommended Citation
Sundberg J,
Hordinsky M,
Bergfeld W,
Lenzy Y,
McMichael A,
Christiano A,
McGregor T,
Stenn K,
Sivamani R,
Pratt CH,
King L.
Cicatricial Alopecia Research Foundation meeting, May 2016: Progress towards the diagnosis, treatment and cure of primary cicatricial alopecias. Exp Dermatol 2018 Mar; 27(3):302-310.