Single-cell transcriptomics defines Dot1L interacting partners and downstream target genes in the mouse molar dental pulp.

Rosa Guzzo
Badam Enkhmandakh
Timothy Becker
Pujan Joshi
Paul Robson, The Jackson Laboratory
Anushree Vijaykumar
Mina Mina
Dong-Guk Shin
Dashzeveg Bayarsaihan

Abstract

Although histone methyltransferases are implicated in many key developmental processes, the contribution of individual chromatin modifiers in dental tissues is not well understood. Using single-cell RNA sequencing, we examined the expression profiles of the disruptor of telomeric silencing 1-like (