Submissions from 2023
Human Hematopoietic Stem Cell Engrafted IL-15 Transgenic NSG Mice Support Robust NK Cell Responses and Sustained HIV-1 Infection., Shawn A Abeynaike, Tridu R Huynh, Abeera Mehmood, Teha Kim, Kayla Frank, Kefei Gao, Cristina Zalfa, Angel Gandarilla, Leonard D. Shultz, and Silke Paust
"FunDNAmethyl" Mechanism for Developmental Restriction of a β-Cell Subpopulation., Cristina Aguayo-Mazzucato and Michael L. Stitzel
GBMdeconvoluteR accurately infers proportions of neoplastic and immune cell populations from bulk glioblastoma transcriptomics data., Shoaib Ajaib, Disha Lodha, Steven Pollock, Gemma Hemmings, Martina A Finetti, Arief Gusnanto, Aruna Chakrabarty, Azzam Ismail, Erica Wilson, Frederick S Varn, Bethany Hunter, Andrew Filby, Asa A Brockman, David McDonald, Roel G W Verhaak, Rebecca A Ihrie, and Lucy F Stead
Inherited deletion of 9p22.3-p24.3 and duplication of 18p11.31-p11.32 associated with neurodevelopmental delay: Phenotypic matching of involved genes., Naser Ajami, Mohammad Amin Kerachian, Mehran Beiraghi Toosi, Farah Ashrafzadeh, Susan Hosseini, Peter N Robinson, and Mohammad Reza Abbaszadegan
Subclonal evolution and expansion of spatially distinct THY1-positive cells is associated with recurrence in glioblastoma., Wajd N Al-Holou, Hanxiao Wang, Visweswaran Ravikumar, Sunita Shankar, Morgan Oneka, Ziad Fehmi, Roel G W Verhaak, Hoon Kim, Drew Pratt, Sandra Camelo-Piragua, Corey Speers, Daniel R Wahl, Todd Hollon, Oren Sagher, Jason A Heth, Karin M Muraszko, Theodore S Lawrence, Ana C de Carvalho, Tom Mikkelsen, Arvind Rao, and Alnawaz Rehemtulla
Challenges and opportunities for modeling aging and cancer., Olga Anczuków, Susan Airhart, Jeffrey Chuang, Lisa M Coussens, George A Kuchel, Ron Korstanje, Sheng Li, Anna Lisa Lucido, Sandra S McAllister, Katerina Politi, Kornelia Polyak, Timothy Ratliff, Guangwen Ren, Jennifer J. Trowbridge, Duygu Ucar, and Karolina Palucka
Predictive models of long COVID., Blessy Antony, Hannah Blau, Elena Casiraghi, Johanna J Loomba, Tiffany J Callahan, Bryan J Laraway, Kenneth J Wilkins, Corneliu C Antonescu, Giorgio Valentini, Andrew E Williams, Peter N Robinson, Justin T Reese, T M Murali, and on behalf of the N3C consortium.
Variation in the CENP-A sequence association landscape across diverse inbred mouse strains., Uma P Arora, Beth A Sullivan, and Beth L Dumont
NOD-scid IL2rγnull mice lacking TLR4 support human immune system development and the study of human-specific innate immunity., Ken-Edwin Aryee, Leonard D. Shultz, Lisa M Burzenski, Dale L Greiner, and Michael A Brehm
Open drug discovery in Alzheimer's disease., Alison D Axtman, Paul E Brennan, Tristan Frappier-Brinton, Ranjita Betarbet, Gregory W. Carter, Haian Fu, Opher Gileadi, Anna K Greenwood, Karina Leal, Frank M Longo, Lara M Mangravite, Aled M Edwards, Allan I Levey, and The Emory-Sage-SGC TREAT-AD Center.
Genetic dissection of the pluripotent proteome through multi-omics data integration., Selcan Aydin, Duy T Pham, Tian Zhang, Gregory R Keele, Daniel A Skelly, Joao A Paulo, Matthew Pankratz, Ted Choi, Steven P Gygi, Laura G Reinholdt, Christopher L. Baker, Gary Churchill, and Steven C. Munger
Inferring cell-type-specific causal gene regulatory networks during human neurogenesis., Nil Aygün, Dan Liang, Wesley L Crouse, Gregory R Keele, Michael I Love, and Jason L Stein
Repeated dosing with cocaine produces strain-dependent effects on responding for conditioned reinforcement in Collaborative Cross mice., Lauren S Bailey, Jared R Bagley, James D Wherry, Elissa J Chesler, Anushree Karkhanis, James D Jentsch, and Lisa M Tarantino
A novel human tau knock-in mouse model reveals interaction of Abeta and human tau under progressing cerebral amyloidosis in 5xFAD mice., Susan Barendrecht, An Schreurs, Stefanie Geissler, Victor Sabanov, Victoria Ilse, Vera Rieckmann, Rico Eichentopf, Anja Künemund, Benjamin Hietel, Sebastian Wussow, Katrin Hoffmann, Kerstin Körber-Ferl, Ravi S Pandey, Gregory W. Carter, Hans-Ulrich Demuth, Max Holzer, Steffen Roßner, Stephan Schilling, Christoph Preuss, Detlef Balschun, and Holger Cynis
L-cysteine ethyl ester prevents and reverses acquired physical dependence on morphine in male Sprague Dawley rats., James N Bates, Paulina M Getsy, Gregory A Coffee, Santhosh M Baby, Peter M MacFarlane, Yee-Hsee Hsieh, Zackery T Knauss, Jason A. Bubier, Devin Mueller, and Stephen J Lewis
Mechanism of STMN2 cryptic splice-polyadenylation and its correction for TDP-43 proteinopathies, Michael W Baughn, Ze'ev Melamed, Jone López-Erauskin, Melinda S Beccari, Karen Ling, Aamir Zuberi, Maximiliano Presa, Elena Gonzalo-Gil, Roy Maimon, Sonia Vazquez-Sanchez, Som Chaturvedi, Mariana Bravo-Hernández, Vanessa Taupin, Stephen Moore, Jonathan W Artates, Eitan Acks, I Sandra Ndayambaje, Ana R Agra de Almeida Quadros, Paayman Jafar-Nejad, Frank Rigo, C Frank Bennett, Cathleen Lutz, Clotilde Lagier-Tourenne, and Don W Cleveland
The Mouse Models of Human Cancer database (MMHCdb)., Dale A. Begley, Debra M Krupke, John P Sundberg, Emily L Jocoy, Joel E Richardson, Steven Neuhauser, and Carol J Bult
The study of selection signature and its applications on identification of candidate genes using whole genome sequencing data in chicken-a review., Semiu Folaniyi Bello, Raman Akinyanju Lawal, Adeniyi Charles Adeola, and Qinghua Nie
Polygenic influences on the behavioral effects of alcohol withdrawal in a mixed-ancestry population from the collaborative study on the genetics of alcoholism (COGA)., Chelsie E Benca-Bachman, Jason A. Bubier, Rameez A Syed, Pamela N Romero Villela, and Rohan H C Palmer
Pre-Covid-19, SARS-CoV-2-Negative Multisystem Inflammatory Syndrome in Children., Sarah Benezech, Liliane Khoryati, Jade Cognard, Stejara A Netea, Taushif Khan, Marion Moreews, Kahina Saker, Jean-Marie De Guillebon, Samira Khaldi-Plassart, Rémi Pescarmona, Sebastien Viel, Christophe Malcus, Magali Perret, Meriadeg Ar Gouilh, Astrid Vabret, Fabienne Venet, Solenn Remy, Emilie Chopin, Gérard Lina, François Vandenesch, Noëmi Rousseaux, Paul Bastard, Shen-Ying Zhang, Jean-Laurent Casanova, Sophie Trouillet-Assant, Thierry Walzer, Taco W Kuijpers, Etienne Javouhey, Olivier Dauwalder, Nico Marr, and Alexandre Belot
Children's Oncology Group's 2023 blueprint for research: Germ cell tumors., Roma Bhuta, Rachana Shah, Joanna J Gell, Jenny N Poynter, Aditya Bagrodia, Bryan J Dicken, Farzana Pashankar, A Lindsay Frazier, and Furqan Shaikh
Microbial glutamate metabolism predicts intravenous cocaine self-administration in diversity outbred mice., Thi Dong Binh Tran; Hoan Nguyen; Erica Sodergren Weinstock; Center for Systems Neurogenetics of Addiction, The Jackson Laboratory; Price E Dickson; Susan N Wright; Vivek M. Philip; George M. Weinstock; Elissa J Chesler; Yanjiao Zhou; and Jason A. Bubier
Mouse Phenome Database: towards a more FAIR-compliant and TRUST-worthy data repository and tool suite for phenotypes and genotypes., Molly A. Bogue, Robyn L Ball, Vivek M. Philip, David O Walton, Matthew H Dunn, Georgi Kolishovski, Anna Lamoureux, Matthew Gerring, Hongping Liang, Jake Emerson, Timothy M Stearns, Hao He, Gaurab Mukherjee, John Bluis, Sejal Desai, Beth A. Sundberg, Beena Kadakkuzha, Govindarajan Kunde-Ramamoorthy, and Elissa J Chesler
Mouse phenome database: curated data repository with interactive multi-population and multi-trait analyses., Molly A. Bogue, Robyn L Ball, David O Walton, Matthew H Dunn, Georgi Kolishovski, Alexander Berger, Anna Lamoureux, Stephen C. Grubb, Matthew Gerring, Matthew Kim, Hongping Liang, Jake Emerson, Timothy M Stearns, Hao He, Gaurab Mukherjee, John Bluis, Sara Davis, Sejal Desai, Beth A. Sundberg, Beena Kadakkuzha, Govindarajan Kunde-Ramamoorthy, Vivek M. Philip, and Elissa J Chesler
Human MCTS1-dependent translation of JAK2 is essential for IFN-γ immunity to mycobacteria., Jonathan Bohlen, Qinhua Zhou, Quentin Philippot, Masato Ogishi, Darawan Rinchai, Tea Nieminen, Simin Seyedpour, Nima Parvaneh, Nima Rezaei, Niloufar Yazdanpanah, Mana Momenilandi, Clément Conil, Anna-Lena Neehus, Carltin Schmidt, Carlos A Arango-Franco, Tom Le Voyer, Taushif Khan, Rui Yang, Julia Puchan, Lucia Erazo, Mykola Roiuk, Taja Vatovec, Zarah Janda, Ivan Bagarić, Marie Materna, Adrian Gervais, Hailun Li, Jérémie Rosain, Jessica N Peel, Yoann Seeleuthner, Ji Eun Han, Anne-Sophie L'Honneur, Marcela Moncada-Vélez, Marta Martin-Fernandez, Michael E Horesh, Tatiana Kochetkov, Monika Schmidt, Mohammed A AlShehri, Eeva Salo, Harri Saxen, Gehad ElGhazali, Ahmad Yatim, Camille Soudée, Federica Sallusto, Armin Ensser, Nico Marr, Peng Zhang, Dusan Bogunovic, Aurélie Cobat, Mohammad Shahrooei, Vivien Béziat, Laurent Abel, Xiaochuan Wang, Stéphanie Boisson-Dupuis, Aurelio A Teleman, Jacinta Bustamante, Qian Zhang, and Jean-Laurent Casanova
Mouse models for immuno-oncology., Marcus Bosenberg, Edison Liu, Chun I. Yu, and Karolina Palucka
RNA splicing dysregulation and the hallmarks of cancer., Robert K Bradley and Olga Anczuków
Escherichia coli ST131 Associated with Increased Mortality in Bloodstream Infections from Urinary Tract Source., Amanda Brumwell, Granger Sutton, Paul M Lantos, Kate Hoffman, Felicia Ruffin, Lauren Brinkac, Thomas H Clarke, Mark D Adams, Vance G Fowler, Derrick E Fouts, and Joshua T Thaden
Genetics and Genomics of Addiction., Jason A. Bubier
The alliance of genome resources: transforming comparative genomics., Carol J Bult and Paul W Sternberg
tRNA Dysregulation in Neurodevelopmental and Neurodegenerative Diseases., Robert W. Burgess and Erik Storkebaum
Spatiotemporally organized immunomodulatory response to SARS-CoV-2 virus in primary human broncho-alveolar epithelia., Diana Cadena, Sonia Jangra, Marina Yurieva, Jan Martinek, Megan Callender, Matthew Coxe, Angela Choi, Juan García-Bernalt Diego, Jianan Lin, Te-Chia Wu, Florentina Marches, Damien Chaussabel, Peter Yu, Andrew Salner, Gabrielle Aucello, Jonathan Koff, Briana Hudson, Sarah E Church, Kara Gorman, Esperanza Anguiano, Adolfo García-Sastre, Adam Williams, Michael Schotsaert, and Karolina Palucka
Protocol for establishing primary human lung organoid-derived air-liquid interface cultures from cryopreserved human lung tissue., Diana Cadena, Sonia Jangra, Marina Yurieva, Jan Martinek, Megan Callender, Matthew Coxe, Angela Choi, Juan García-Bernalt Diego, Te-Chia Wu, Florentina Marches, Damien Chaussabel, Adolfo García-Sastre, Michael Schotsaert, Adam Williams, and Karolina Palucka
Ontologizing health systems data at scale: making translational discovery a reality., Tiffany J Callahan, Adrianne L Stefanski, Jordan M Wyrwa, Chenjie Zeng, Anna Ostropolets, Juan M Banda, William A Baumgartner, Richard D Boyce, Elena Casiraghi, Ben D Coleman, Janine H Collins, Sara J Deakyne Davies, James A Feinstein, Asiyah Y Lin, Blake Martin, Nicolas A Matentzoglu, Daniella Meeker, Justin Reese, Jessica Sinclair, Sanya B Taneja, Katy E Trinkley, Nicole A Vasilevsky, Andrew E Williams, Xingmin A Zhang, Joshua C Denny, Patrick B Ryan, George Hripcsak, Tellen D Bennett, Melissa A Haendel, Peter N Robinson, Lawrence E Hunter, and Michael G Kahn
Rethinking Remapping: Circuit Mechanisms of Recovery after Stroke., Baruc Campos, Hoseok Choi, Andrew T DeMarco, Anna Seydell-Greenwald, Sara J Hussain, Mary T Joy, Peter E Turkeltaub, and William Zeiger
Assessment of brain cancer atlas maps with multimodal imaging features., Enrico Capobianco and Marco Dominietto
Translating Data Science Results into Precision Oncology Decisions: A Mini Review., Enrico Capobianco and Marco Dominietto
Vitamin D inhibits osteosarcoma by reprogramming nonsense-mediated RNA decay and SNAI2-mediated epithelial-to-mesenchymal transition., Enrico Capobianco, Vanessa McGaughey, Gerbenn Seraphin, John Heckel, Sandra Rieger, and Thomas S Lisse
Complexity of the marine ecosystem in view of the human health factors: role of network science, Enrico Capobianco and Pier Francesco Moretti
GRAPE for fast and scalable graph processing and random-walk-based embedding, Luca Cappelletti, Tommaso Fontana, Elena Casiraghi, Vida Ravanmehr, Tiffany J. Callahan, Carlos Cano, Marcin P. Joachimiak, Christopher J. Mungall, Peter N Robinson, Justin Reese, and Giorgio Valentini
A data-driven optimization method for coarse-graining gene regulatory networks., Cristian Caranica and Mingyang Lu
The Medical Action Ontology: A tool for annotating and analyzing treatments and clinical management of human disease., Leigh Carmody, Michael Gargano, Sabrina Toro, Nicole A Vasilevsky, Margaret P Adam, Hannah Blau, Lauren E Chan, David Gomez-Andres, Rita Horvath, Megan L Kraus, Markus S Ladewig, David Lewis-Smith, Hanns Lochmüller, Nicolas A Matentzoglu, Monica C Munoz-Torres, Catharina Schuetz, Berthold Seitz, Morgan N Similuk, Teresa N Sparks, Timmy Strauss, Emilia M Swietlik, Rachel Thompson, Xingmin Aaron Zhang, Christopher J Mungall, Melissa A Haendel, and Peter N Robinson
Widespread perturbation of ETS factor binding sites in cancer., Sebastian Carrasco Pro, Heather Hook, David Bray, Daniel Berenzy, Devlin Moyer, Meimei Yin, Adam Thomas Labadorf, Ryan Tewhey, Trevor Siggers, and Juan Ignacio Fuxman Bass
A method for comparing multiple imputation techniques: A case study on the U.S. national COVID cohort collaborative., Elena Casiraghi, Rachel Wong, Margaret Hall, Ben D Coleman, Marco Notaro, Michael D Evans, Jena S Tronieri, Hannah Blau, Bryan Laraway, Tiffany J Callahan, Lauren E Chan, Carolyn T Bramante, John B Buse, Richard A Moffitt, Til Stürmer, Steven G Johnson, Yu Raymond Shao, Justin Reese, Peter N Robinson, Alberto Paccanaro, Giorgio Valentini, Jared D Huling, and Kenneth J Wilkins
Extending support for mouse data in the Molecular Signatures Database (MSigDB)., Anthony S Castanza, Jill M. Recla, David Eby, Helga Thorvaldsdóttir, Carol J Bult, and Jill P Mesirov
KG-Hub-building and exchanging biological knowledge graphs., J Harry Caufield, Tim Putman, Kevin Schaper, Deepak R Unni, Harshad Hegde, Tiffany J Callahan, Luca Cappelletti, Sierra A T Moxon, Vida Ravanmehr, Seth Carbon, Lauren E Chan, Katherina Cortes, Kent A Shefchek, Glass Elsarboukh, Jim Balhoff, Tommaso Fontana, Nicolas Matentzoglu, Richard M Bruskiewich, Anne E Thessen, Nomi L Harris, Monica C Munoz-Torres, Melissa A Haendel, Peter N Robinson, Marcin P Joachimiak, Christopher J Mungall, and Justin T Reese
Evaluation of Associations of Growth Differentiation Factor-11, Growth Differentiation Factor-8, and Their Binding Proteins, Follistatin and Follistatin-Like Protein-3, With Measures of Skeletal Muscle Mass, Muscle Strength, and Physical Function in Older Adults., Peggy M Cawthon, Sheena Patel, Anne B Newman, Shalender Bhasin, Liming Peng, Russell P Tracy, Jorge R Kizer, Se-Jin Lee, Luigi Ferrucci, Peter Ganz, Nathan K LeBrasseur, and Steven R Cummings
ChIATAC is an efficient strategy for multi-omics mapping of 3D epigenomes from low-cell inputs., Haoxi Chai, Harianto Tjong, Peng Li, Wei Liao, Ping Wang, Chee-Hong Wong, Chew Yee Ngan, Warren J Leonard, Chia-Lin Wei, and Yijun Ruan
The Environmental Conditions, Treatments, and Exposures Ontology (ECTO): connecting toxicology and exposure to human health and beyond., Lauren E Chan, Anne E Thessen, William D Duncan, Nicolas Matentzoglu, Charles Schmitt, Cynthia J Grondin, Nicole Vasilevsky, Julie A McMurry, Peter N Robinson, Christopher J Mungall, and Melissa A Haendel
Cancer-associated mesothelial cells are regulated by the anti-Müllerian hormone axis., M Chauvin, M-C Meinsohn, S Dasari, P May, S Iyer, N M P Nguyen, E Oliva, Z Lucchini, N Nagykery, A Kashiwagi, R Mishra, Richard S. Maser, Julie Wells, Carol J Bult, A K Mitra, Patricia K Donahoe, and D Pépin
Genome-wide screening reveals the genetic basis of mammalian embryonic eye development., Justine M Chee, Louise Lanoue, Dave Clary, Kendall Higgins, Lynette Bower, Ann Flenniken, Ruolin Guo, David J Adams, Fatima Bosch, Robert E Braun, Steve D M Brown, H-J Genie Chin, Mary E Dickinson, Chih-Wei Hsu, Michael Dobbie, Xiang Gao, Sanjeev Galande, Anne Grobler, Jason D Heaney, Yann Herault, Martin Hrabe de Angelis, Fabio Mammano, Lauryl M J Nutter, Helen Parkinson, Chuan Qin, Toshi Shiroishi, Radislav Sedlacek, J-K Seong, Ying Xu, Brian Brooks, Colin McKerlie, K C Kent Lloyd, Henrik Westerberg, and Ala Moshiri
Genetic architecture of heart mitochondrial proteome influencing cardiac hypertrophy., Karthickeyan Chella Krishnan, Elie-Julien El Hachem, Mark P Keller, Sanjeet G Patel, Luke Carroll, Alexis Diaz Vegas, Isabela Gerdes Gyuricza, Christine Light, Yang Cao, Calvin Pan, Karolina Elżbieta Kaczor-Urbanowicz, Varun Shravah, Diana Anum, Matteo Pellegrini, Chi Fung Lee, Marcus M Seldin, Nadia Rosenthal, Gary Churchill, Alan D Attie, Benjamin Parker, David E James, and Aldons J Lusis
Translocation detection from Hi-C data via scan statistics., Anthony Cheng, Disheng Mao, Yuping Zhang, Joseph Glaz, and Zhengqing Ouyang
Global genetic diversity, introgression, and evolutionary adaptation of indicine cattle revealed by whole genome sequencing., Ningbo Chen, Xiaoting Xia, Quratulain Hanif, Fengwei Zhang, Ruihua Dang, Bizhi Huang, Yang Lyu, Xiaoyu Luo, Hucai Zhang, Huixuan Yan, Shikang Wang, Fuwen Wang, Jialei Chen, Xiwen Guan, Yangkai Liu, Shuang Li, Liangliang Jin, Pengfei Wang, Luyang Sun, Jicai Zhang, Jianyong Liu, Kaixing Qu, Yanhong Cao, Junli Sun, Yuying Liao, Zhengzhong Xiao, Ming Cai, Lan Mu, Amam Zonaed Siddiki, Muhammad Asif, Shahid Mansoor, Masroor Ellahi Babar, Tanveer Hussain, Gamamada Liyanage Lalanie Pradeepa Silva, Neena Amatya Gorkhali, Endashaw Terefe, Gurja Belay, Abdulfatai Tijjani, Tsadkan Zegeye, Mebrate Genet Gebre, Yun Ma, Yu Wang, Yongzhen Huang, Xianyong Lan, Hong Chen, Nicola Rambaldi Migliore, Giulia Colombo, Ornella Semino, Alessandro Achilli, Mikkel-Holger S Sinding, Johannes A Lenstra, Haijian Cheng, Wenfa Lu, Olivier Hanotte, Jianlin Han, Yu Jiang, and Chuzhao Lei
HIV associated cell death: Peptide-induced apoptosis restricts viral transmission., Qiongyu Chen, Yan Zhao, Yonghong Zhang, Jianbo Zhang, Wenshu Lu, Chih-Hao Chang, and Shisong Jiang
Epigenetic memory of coronavirus infection in innate immune cells and their progenitors., Jin-Gyu Cheong, Arjun Ravishankar, Siddhartha Sharma, Christopher N Parkhurst, Simon A Grassmann, Claire K Wingert, Paoline Laurent, Sai Ma, Lucinda Paddock, Isabella C Miranda, Emin Onur Karakaslar, Djamel Nehar-Belaid, Asa Thibodeau, Michael J Bale, Vinay K Kartha, Jim K Yee, Minh Y Mays, Chenyang Jiang, Andrew W Daman, Alexia Martinez de Paz, Dughan Ahimovic, Victor Ramos, Alexander Lercher, Erik Nielsen, Sergio Alvarez-Mulett, Ling Zheng, Andrew Earl, Alisha Yallowitz, Lexi Robbins, Elyse LaFond, Karissa L Weidman, Sabrina Racine-Brzostek, He S Yang, David R Price, Louise Leyre, André F Rendeiro, Hiranmayi Ravichandran, Junbum Kim, Alain C Borczuk, Charles M Rice, R Brad Jones, Edward J Schenck, Robert J Kaner, Amy Chadburn, Zhen Zhao, Virginia Pascual, Olivier Elemento, Robert E Schwartz, Jason D Buenrostro, Rachel E Niec, Franck J Barrat, Lindsay Lief, Joseph C Sun, Duygu Ucar, and Steven Z Josefowicz
Enhanced performance of gene expression predictive models with protein-mediated spatial chromatin interactions., Mateusz Chiliński, Jakub Lipiński, Abhishek Agarwal, Yijun Ruan, and Dariusz Plewczynski
Autologous humanized PDX modeling for immuno-oncology recapitulates features of the human tumor microenvironment., Michael Chiorazzi, Jan Martinek, Bradley Krasnick, Yunjiang Zheng, Keenan J Robbins, Rihao Qu, Gabriel Kaufmann, Zachary Skidmore, Melani Juric, Laura A Henze, Frederic Brösecke, Adam Adonyi, Jun Zhao, Liang Shan, Esen Sefik, Jacqueline Mudd, Ye Bi, S Peter Goedegebuure, Malachi Griffith, Obi Griffith, Abimbola Oyedeji, Sofia Fertuzinhos, Rolando Garcia-Milian, Daniel Boffa, Frank Detterbeck, Andrew Dhanasopon, Justin Blasberg, Benjamin Judson, Scott Gettinger, Katerina Politi, Yuval Kluger, Karolina Palucka, Ryan C Fields, and Richard A Flavell
BMP10 functions independently from BMP9 for the development of a proper arteriovenous network., Hyunwoo Choi, Bo-Gyeong Kim, Yong Hwan Kim, Se-Jin Lee, Young Jae Lee, and S Paul Oh
A new era in quantification of animal social behaviors., Jessica D Choi and Vivek Kumar
Neuronal diversity can improve machine learning for physics and beyond., Anshul Choudhary, Anil Radhakrishnan, John F Lindner, Sudeshna Sinha, and William L Ditto
Humanized mouse models for immuno-oncology research., Jane Chuprin, Hannah Buettner, Mina O Seedhom, Dale L Greiner, James G. Keck, Fumihiko Ishikawa, Leonard D. Shultz, and Michael A Brehm
Heterogeneity of Islet-Infiltrating IL-21+ CD4 T Cells in a Mouse Model of Type 1 Diabetes., Ashley E Ciecko, Yu Wang, Stephanie Harleston, Amber Drewek, David V. Serreze, Aron M Geurts, Chien-Wei Lin, and Yi-Guang Chen
A quantitative evaluation of topological motifs and their coupling in gene circuit state distributions., Benjamin Clauss and Mingyang Lu
High-resolution microbiome analysis reveals exclusionary Klebsiella species competition in preterm infants at risk for necrotizing enterocolitis., Spencer Coleman, Katrin Unterhauser, Karim Rezaul, Nagender Ledala, Stephanie Lesmes, Melissa J Caimano, Yanjiao Zhou, Eric Jackson, Dawn Gratalo, Mark D Driscoll, and Adam P Matson
Hematopoietic stem cell aging and leukemia transformation., Patricia A Colom Díaz, Jayna J Mistry, and Jennifer J. Trowbridge
Protein coding variation in the J:ARC and J:DO outbred laboratory mouse stocks provides a molecular basis for distinct research applications., Belinda Cornes, Carolyn Paisie, Emily Swanzey, Peter D Fields, Andrew Schile, Kelly Brackett, Laura G Reinholdt, and Anuj Srivastava
Application of 4-D ultrasound-derived regional strain and proteomics analysis in, Frederick W Damen, Daniel P Gramling, Dorothy Ahlf Wheatcraft, Robert Y Wilpan, Mauro W Costa, and Craig J Goergen
On the benefits of the tryptophan metabolite 3-hydroxyanthranilic acid in Caenorhabditis elegans and mouse aging., Hope Dang, Raul Castro-Portuguez, Luis Espejo, Grant Backer, Samuel Freitas, Erica Spence, Jeremy Meyers, Karissa Shuck, Emily A Gardea, Leah M Chang, Jonah Balsa, Niall Thorns, Caroline Corban, Teresa Liu, Shannon Bean, Susan Sheehan, Ron Korstanje, and George L Sutphin
Phenopacket-tools: Building and validating GA4GH Phenopackets., Daniel Danis, Julius O B Jacobsen, Alex H Wagner, Tudor Groza, Martha A Beckwith, Lauren Rekerle, Leigh Carmody, Justin Reese, Harshad Hegde, Markus S Ladewig, Berthold Seitz, Monica Munoz-Torres, Nomi L Harris, Jordi Rambla, Michael Baudis, Christopher J Mungall, Melissa A Haendel, and Peter N Robinson
A new fasciocutaneous flap model identifies a critical role for endothelial Notch signaling in wound healing and flap survival., Khaled Dastagir, Jaba Gamrekelashvili, Nadjib Dastagir, Anne Limbourg, Dustin Kijas, Tamar Kapanadze, Peter M Vogt, and Florian P Limbourg
Cognitive impairment in post-acute sequelae of COVID-19 and short duration myalgic encephalomyelitis patients is mediated by orthostatic hemodynamic changes., Heather Day, Brayden Yellman, Sarah Hammer, Candace Rond, Jennifer Bell, Saeed Abbaszadeh, Greg Stoddard, Derya Unutmaz, Lucinda Bateman, and Suzanne D Vernon
Epithelial mechanics are maintained by inhibiting cell fusion with age in Drosophila., Ari S Dehn, Levi Duhaime, Navdeep Gogna, Patsy M. Nishina, Kristina Kelley, and Vicki P Losick
Generation of the NeoThy mouse model for human immune system studies., Natalia M Del Rio, Liupei Huang, Lydia Murphy, Jayalaxmi Suresh Babu, Cross Matthew Daffada, William John Haynes, James G Keck, Michael A Brehm, Leonard D. Shultz, and Matthew E Brown
High-throughput bioprinting of the nasal epithelium using patient-derived nasal epithelial cells., I Deniz Derman, Miji Yeo, Diana Cadena, Megan Callender, Mian Horvath, Zengshuo Mo, Ruoyun Xiong, Elizabeth Fleming, Phylip Chen, Mark E Peeples, Karolina Palucka, Julia Oh, and Ibrahim T Ozbolat
Perivascular cells induce microglial phagocytic states and synaptic engulfment via SPP1 in mouse models of Alzheimer's disease., Sebastiaan De Schepper, Judy Z Ge, Gerard Crowley, Laís S S Ferreira, Dylan Garceau, Christina E Toomey, Dimitra Sokolova, Javier Rueda-Carrasco, Sun-Hye Shin, Jung-Seok Kim, Thomas Childs, Tammaryn Lashley, Jemima J Burden, Michael Sasner, Carlo Sala Frigerio, Steffen Jung, and Soyon Hong
Urban-Rural and Socioeconomic Differences in Patient Knowledge and Perceptions of Genomic Tumor Testing., Jessica F DiBiase, Elizabeth Scharnetzki, Emily A Edelman, F Lee Lucas, Petra Helbig, Jens Rueter, Paul K J Han, Erika Ziller, Elizabeth A Jacobs, and Eric C Anderson
Identification of a humanized mouse model for functional testing of immune-mediated biomaterial foreign body response., Joshua C Doloff, Minglin Ma, Atieh Sadraei, Hok Hei Tam, Shady Farah, Jennifer Hollister-Lock, Arturo J Vegas, Omid Veiseh, Victor M Quiroz, Amanda Rakoski, Stephanie Aresta-DaSilva, Andrew R Bader, Marissa Griffin, Gordon C Weir, Michael A Brehm, Leonard D. Shultz, Robert Langer, Dale L Greiner, and Daniel G Anderson
ACDA: implementation of an augmented drug synergy prediction algorithm., Sergii Domanskyi, Emily L Jocoy, Anuj Srivastava, and Carol J Bult
MATR3 P154S knock-in mice do not exhibit motor, muscle or neuropathologic features of ALS., Marissa Dominick, Nicole Houchins, Vinisha Venugopal, Aamir Zuberi, Cathleen Lutz, Bessie Meechooveet, Kendall Van Keuren-Jensen, Robert Bowser, and David X Medina
Discovery of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic approach for Alzheimer's disease., Yuhong Du, William J Bradshaw, Tina M Leisner, Joel K Annor-Gyamfi, Kun Qian, Frances M Bashore, Arunima Sikdar, Felix O Nwogbo, Andrey A Ivanov, Stephen V Frye, Opher Gileadi, Paul E Brennan, Allan I Levey, The Emory-Sage-SGC TREAT-AD Center, Alison D Axtman, Kenneth H Pearce, Haian Fu, and Vittorio L Katis
Possibilities and pitfalls of practitioners in trying to apply change theory as viewed through the lens of Reinholz, White, and Andrews “Change theory in STEM higher education: a systematic review, Melissa Elben-Zayas, Laura J Muller, and Janet Russell
Identification of a heterogeneous and dynamic ciliome during embryonic development and cell differentiation., Kelsey H Elliott, Sai K Balchand, Christian Louis Bonatto Paese, Ching-Fang Chang, Yanfen Yang, Kari M Brown, Daniel T Rasicci, Hao He, Konrad Thorner, Praneet Chaturvedi, Stephen A. Murray, Jing Chen, Aleksey Porollo, Kevin A Peterson, and Samantha A Brugmann
Identification of a heterogeneous and dynamic ciliome during embryonic development and cell differentiation., Kelsey H Elliott, Sai K Balchand, Christian Louis Bonatto Paese, Ching-Fang Chang, Yanfen Yang, Kari M Brown, Daniel T Rasicci, Hao He, Konrad Thorner, Praneet Chaturvedi, Stephen A. Murray, Jing Chen, Aleksey Porollo, Kevin A Peterson, and Samantha A Brugmann
CHEK2 signaling is the key regulator of oocyte survival after chemotherapy., Chihiro Emori, Zachary Boucher, and Ewelina Bolcun-Filas
Co-option of endogenous retroviruses through genetic escape from TRIM28 repression., Rocio Enriquez-Gasca, Poppy A Gould, Hale Tunbak, Lucia Conde, Javier Herrero, Alexandra Chittka, Christine R Beck, Robert Gifford, and Helen M Rowe
Concomitant inhibition of PPARγ and mTORC1 induces the differentiation of human monocytes into highly immunogenic dendritic cells., Fernando Erra Diaz, Ignacio Mazzitelli, Lucía Bleichmar, Claudia Melucci, Asa Thibodeau, Tomás Dalotto Moreno, Radu Marches, Gabriel A Rabinovich, Duygu Ucar, and Jorge Geffner
A novel HSPB1S139F mouse model of Charcot-Marie-Tooth Disease, Keila S Espinoza, Kyra N Hermanson, Cameron A Beard, Nicholas U Schwartz, Justin M Snider, Benjamin E. Low, Michael V. Wiles, Yusuf A Hannun, Lina M Obeid, and Ashley J Snider
Editorial: Targeting glucose metabolism in cancer immunity and immunotherapy., Olivier Feron, Chih-Hao Chang, and Frédérique Végran
Resolution of structural variation in diverse mouse genomes reveals chromatin remodeling due to transposable elements., Ardian Ferraj, Peter A Audano, Parithi Balachandran, Anne M Czechanski, Jacob I Flores, Alexander A Radecki, Varun Mosur, David S Gordon, Isha A Walawalkar, Evan E Eichler, Laura G Reinholdt, and Christine R Beck
Chromosome-Level Genome Assembly for the Angiosperm Silene conica., Peter D Fields, Melody M Weber, Gus Waneka, Amanda K Broz, and Daniel B Sloan
Neurobehavioral deficits of mice expressing a low level of G127V mutant frataxin., Daniel Fil, Robbie L Conley, Aamir Zuberi, Cathleen Lutz, Terry Gemelli, Marek Napierala, and Jill S Napierala
New allele of mouse DNA/RNA helicase senataxin causes meiotic arrest and infertility, Yasuhiro Fujiwara, Kouhei Saito, Fengyun Sun, Sabrina Petri, Erina Inoue, John Schimenti, Yuki Okada, and Mary Ann Handel
Microbiota-dependent proteolysis of gluten subverts diet-mediated protection against type 1 diabetes., Matthew C Funsten, Leonid A Yurkovetskiy, Andrey Kuznetsov, Derek Reiman, Camilla H F Hansen, Katharine I Senter, Jean Lee, Jeremy Ratiu, Shiva Dahal-Koirala, Dionysios A Antonopoulos, Gary M Dunny, Ludvig M Sollid, David Serreze, Aly A Khan, and Alexander V Chervonsky
Centromere innovations within a mouse species., Craig W Gambogi, Nootan Pandey, Jennine M Dawicki-McKenna, Uma P Arora, Mikhail A Liskovykh, Jun Ma, Piero Lamelza, Vladimir Larionov, Michael A Lampson, Glennis A Logsdon, Beth L Dumont, and Ben E Black
Citizen science data reveal regional heterogeneity in phenological response to climate in the large milkweed bug,, Alexis Garretson, Tedra Cuddy, Alexandra G Duffy, iNaturalist Citizen Scientists, and Rebecca E Forkner
Reproductive genomics of the mouse: implications for human fertility and infertility., Alexis Garretson, Beth L Dumont, and Mary Ann Handel
The trouble with triples: Examining the impact of measurement error in mediation analysis., Madeleine S Gastonguay, Gregory R Keele, and Gary Churchill
Maintenance of Human Primordial Germ Cell-Like Cells in a Long-Term Culture System., Joanna J Gell and Toshi Shioda
The RNA-binding protein FUS/TLS interacts with SPO11 and PRDM9 and localize at meiotic recombination hotspots., Teresa Giannattasio, Erika Testa, Ramona Palombo, Lidia Chellini, Flavia Franceschini, Álvaro Crevenna, Petko M. Petkov, Maria Paola Paronetto, and Marco Barchi