Clonal hematopoiesis, aging and Alzheimer's disease.
Sánchez Vela P,
Clonal hematopoiesis, aging and Alzheimer's disease. Nat Med. 2023;29(7):1605-6.
JMG, Humans, Clonal Hematopoiesis, Alzheimer Disease, Aging, Hematopoiesis, Mutation, Cardiovascular Diseases
Nat Med. 2023;29(7):1605-6.
Work in the Levine Lab is supported by US National Institutes of Health–National Cancer Institute Cancer Center Support Grant P30 CA008748, and work in the Trowbridge and Levine labs is supported by National Cancer Institute–National Institute on Aging grant U01AG077925-01. The Trowbridge lab is supported by US National Institutes of Health– National Cancer Institute Cancer Center Support Grant P30 CA034196, US National Institutes of Health grants R01DK118072 and R01AG069010, EvansMDS, and The Mark Foundation. J.J.T. is a Scholar of the Leukemia & Lymphoma Society. P.S.V. is supported by a grant from Cycle for Survival at Memorial Sloan Kettering Cancer Center and was previously supported by the Mark Foundation.
Unexpectedly, new data show that clonal hematopoiesis is associated with protection from Alzheimer’s disease; it is imperative that future studies unravel the complex tissue– disease contexts in which clonal hematopoiesis arises and contributes to aging-associated diseases.