Frailty-associated dysbiosis of human microbiotas in older adults in nursing homes.

Document Type

Article

Publication Date

10-1-2022

Keywords

JGM

JAX Source

Nat Aging. 2022;2(10):876-7.

ISSN

2662-8465

PMID

36909933

DOI

https://doi.org/10.1038/s43587-022-00289-7

Abstract

Our longitudinal study comparing the skin, gut and oral microbiomes of community-dwelling older adults and nursing home residents showed striking changes known to be linked to antibiotic resistance and disease risk. Such shifts were associated with frailty, not chronological age, and were most pronounced in the skin, the primary reservoir for infection risk.

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