Document Type

Article

Publication Date

9-1-2024

Keywords

JMG, Animals, Mutation, Genetic Variation, Mice, Phenotype, Mammals

JAX Source

PLoS Biol. 2024;22(9):e3002825.

ISSN

1545-7885

PMID

39331588

DOI

https://doi.org/10.1371/journal.pbio.3002825

Grant

B.L.D. is supported by a Maximizing Investigators’ Research Award from the National Institute of General Medical Sciences (GM133415; https://www.nigms.nih.gov/). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Abstract

New mutations provide the source of all genetic variation but their impact on trait variation remains poorly understood. A new study published in PLOS Biology addresses this question, finding that new mutations exert only weak effects on some traits in mice.

Creative Commons License

Creative Commons Attribution 4.0 International License
This work is licensed under a Creative Commons Attribution 4.0 International License.

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