Submissions from 2024
Genome-matched treatments and patient outcomes in the Maine Cancer Genomics Initiative (MCGI)., Eric C Anderson, John DiPalazzo, F Lee Lucas, Michael J Hall, Andrey Antov, Petra Helbig, Jennifer Bourne, Leah Graham, Lory Gaitor, Christine Lu-Emerson, Leslie S Bradford, Roger Inhorn, Sarah J Sinclair, Philip L Brooks, Christian A Thomas, Karen Rasmussen, Paul K J Han, Edison Liu, and Jens Rueter
Complex regulatory networks influence pluripotent cell state transitions in human iPSCs., Timothy D Arthur, Jennifer P Nguyen, Agnieszka D'Antonio-Chronowska, Hiroko Matsui, Nayara S Silva, Isaac N Joshua, iPSCORE Consortium, André D Luchessi, William W Young Greenwald, Matteo D'Antonio, Martin Pera, and Kelly A Frazer
Small polymorphisms are a source of ancestral bias in structural variant breakpoint placement., Peter A Audano and Christine R Beck
Satellite cells in the growth and maintenance of muscle, John F Bachman and J V. Chakkalakal
GenomeMUSter mouse genetic variation service enables multitrait, multipopulation data integration and analysis., Robyn L Ball, Molly A. Bogue, Hongping Liang, Anuj Srivastava, David G Ashbrook, Anna Lamoureux, Matthew Gerring, Alexander S Hatoum, Matthew J Kim, Hao He, Jake Emerson, Alexander Berger, David O Walton, Keith Sheppard, Baha El Kassaby, Francisco Castellanos, Govindarajan Kunde-Ramamoorthy, Lu Lu, John Bluis, Sejal Desai, Beth A. Sundberg, Gary Peltz, Zhuoqing Fang, Gary Churchill, Robert W Williams, Arpana Agrawal, Carol J Bult, Vivek M. Philip, and Elissa J Chesler
The DO-KB Knowledgebase: a 20-year journey developing the disease open science ecosystem., J Allen Baron, Claudia Sanchez-Beato Johnson, Michael A Schor, Dustin Olley, Lance Nickel, Victor Felix, James B Munro, Susan M. Bello, Cynthia Bearer, Richard Lichenstein, Katharine Bisordi, Rima Koka, Carol Greene, and Lynn M Schriml
Characterization of covalent inhibitors that disrupt the interaction between the tandem SH2 domains of SYK and FCER1G phospho-ITAM., Frances M Bashore, Vittorio L Katis, Yuhong Du, Arunima Sikdar, Dongxue Wang, William J Bradshaw, Karolina A Rygiel, Tina M Leisner, Rod Chalk, Swati Mishra, C Andrew Williams, Opher Gileadi, Paul E Brennan, Jesse C Wiley, Jake Gockley, Gregory Cary, Gregory W. Carter, Jessica E Young, Kenneth H Pearce, Haian Fu, the Emory-Sage-SGC TREAT-AD Center, and Alison D Axtman
L-NAC and L-NAC methyl ester prevent and overcome physical dependence to fentanyl in male rats., James N Bates, Santhosh M Baby, Paulina M Getsy, Gregory A Coffee, Yee-Hsee Hsieh, Zackery T Knauss, Albert Dahan, Jason A. Bubier, Peter M MacFarlane, Devin Mueller, and Stephen J Lewis
Dominant NARS1 mutations causing axonal Charcot-Marie-Tooth disease expand NARS1-associated diseases, Danique Beijer, Sheila Marte, Jiaxin C Li, Willem De Ridder, Jessie Z Chen, Abby Tadenev, Kathy E Miers, Tine Deconinck, Richard Macdonell, Wilson Marques, Peter De Jonghe, Samia L Pratt, Rebecca Meyer-Schuman, Stephan Züchner, Anthony Antonellis, Robert W. Burgess, and Jonathan Baets
Linking immune modulation to cardiac fibrosis, Frank Bengel, Jonathan Epstein, Robert Gropler, Uwe Haberkorn, Rafael Kramann, Kory Lavine, Florian Leuschner, Yongjian Liu, Nadia Rosenthal, and Hao Wu
Gene replacement-Alzheimer's disease (GR-AD): Modeling the genetics of human dementias in mice., Kellie Benzow, Kul Karanjeet, Adrian L Oblak, Gregory W. Carter, Michael Sasner, and Michael D Koob
Digitalization of toxicology: improving preclinical to clinical translation., Brian R Berridge, Szczepan W Baran, Vivek Kumar, Natalie Bratcher-Petersen, Michael Ellis, Chang-Ning Liu, and Timothy L Robertson
Three linked variants have opposing regulatory effects on isovaleryl-CoA dehydrogenase gene expression., Elizabeth A Brown, Susan Kales, Michael James Boyle, Joseph Vitti, Dylan Kotliar, Steve Schaffner, Ryan Tewhey, and Pardis C Sabeti
Design of a targeted blood transcriptional panel for monitoring immunological changes accompanying pregnancy., Tobias Brummaier, Darawan Rinchai, Mohammed Toufiq, Mohammed Y Karim, Tanwir Habib, Jürg Utzinger, Daniel H Paris, Rose McGready, Alexandra K Marr, Tomoshige Kino, Annalisa Terranegra, Souhaila Al Khodor, Damien Chaussabel, and Basirudeen Syed Ahamed Kabeer
Large-scale annotated dataset for cochlear hair cell detection and classification., Christopher J Buswinka, David B Rosenberg, Rubina G Simikyan, Richard T Osgood, Katharine Fernandez, Hidetomi Nitta, Yushi Hayashi, Leslie W Liberman, Emily Nguyen, Erdem Yildiz, Jinkyung Kim, Amandine Jarysta, Justine Renauld, Ella Wesson, Haobing Wang, Punam Thapa, Pierrick Bordiga, Noah McMurtry, Juan Llamas, Siân R Kitcher, Ana I López-Porras, Runjia Cui, Ghazaleh Behnammanesh, Jonathan E Bird, Angela Ballesteros, A Catalina Vélez-Ortega, Albert S B Edge, Michael R Deans, Ksenia Gnedeva, Brikha R Shrestha, Uri Manor, Bo Zhao, Anthony J Ricci, Basile Tarchini, Martín L Basch, Ruben Stepanyan, Lukas D Landegger, Mark A Rutherford, M Charles Liberman, Bradley J Walters, Corné J Kros, Guy P Richardson, Lisa L Cunningham, and Artur A Indzhykulian
Non-genetic mechanisms of drug resistance in acute leukemias., Alexander Calderon, Cuijuan Han, Sadik Karma, and Eric Wang
Sunitinib in Patients With Breast Cancer With, Carmen J Calfa, Michael Rothe, Pam K Mangat, Elizabeth Garrett-Mayer, Eugene R Ahn, Monika L Burness, Keerthi Gogineni, Nitin Rohatgi, Tareq Al Baghdadi, Alison Conlin, Anu Gaba, Omid Hamid, Jairam Krishnamurthy, Naga Jyothi Gavini, Philip J Gold, Jordi Rodon, Jens Rueter, Ramya Thota, Gina N Grantham, Dominique C Hinshaw, Abigail Gregory, Susan Halabi, and Richard L Schilsky
Node-degree aware edge sampling mitigates inflated classification performance in biomedical random walk-based graph representation learning., Luca Cappelletti, Lauren Rekerle, Tommaso Fontana, Peter Hansen, Elena Casiraghi, Vida Ravanmehr, Christopher J Mungall, Jeremy J Yang, Leonard Spranger, Guy Karlebach, J Harry Caufield, Leigh Carmody, Ben D Coleman, Tudor I Oprea, Justin Reese, Giorgio Valentini, and Peter N Robinson
Genetic and multi-omic risk assessment of Alzheimer's disease implicates core associated biological domains., Gregory Cary, Jesse C Wiley, Jake Gockley, Stephen Keegan, Sai Sruthi Amirtha Ganesh, Laura Heath, Robert R Butler, Lara M Mangravite, Benjamin A Logsdon, Frank M Longo, Allan Levey, Anna K Greenwood, and Gregory W. Carter
Structured Prompt Interrogation and Recursive Extraction of Semantics (SPIRES): a method for populating knowledge bases using zero-shot learning., J Harry Caufield, Harshad Hegde, Vincent Emonet, Nomi L Harris, Marcin P Joachimiak, Nicolas Matentzoglu, HyeongSik Kim, Sierra Moxon, Justin T Reese, Melissa A Haendel, Peter N Robinson, and Christopher J Mungall
AAV8 gene therapy reverses cardiac pathology and prevents early mortality in a mouse model of Friedreich's ataxia., Joshua C Chang, Molly R Ryan, Marie C Stark, Su Liu, Pravinkumar Purushothaman, Fria Bolan, Caitlin A Johnson, Mark Champe, Hui Meng, Michael W Lawlor, Sarah Halawani, Lucie V Ngaba, David R Lynch, Crystal Davis, Elena Gonzalo-Gil, Cathleen Lutz, Fabrizia Urbinati, Bala Medicherla, and Carlos Fonck
Predicting nutrition and environmental factors associated with female reproductive disorders using a knowledge graph and random forests., Lauren E Chan, Elena Casiraghi, Justin Reese, Quaker E Harmon, Kevin Schaper, Harshad Hegde, Giorgio Valentini, Charles Schmitt, Alison Motsinger-Reif, Janet E Hall, Christopher J Mungall, Peter N Robinson, and Melissa A Haendel
Minimum information and guidelines for reporting a multiplexed assay of variant effect., Melina Claussnitzer, Victoria N Parikh, Alex H Wagner, Jeremy A Arbesfeld, Carol J Bult, Helen V Firth, Lara A Muffley, Alex N Nguyen Ba, Kevin Riehle, Frederick P Roth, Daniel Tabet, Benedetta Bolognesi, Andrew M Glazer, and Alan F Rubin
An in vitro neurogenetics platform for precision disease modeling in the mouse., Daniel Cortes, Mélanie Escudero, Austin C Korgan, Arojit Mitra, Alyssa Edwards, Selcan Aydin, Steven C. Munger, Kevin Charland, Zhong-Wei Zhang, Kristen M S O'Connell, Laura G Reinholdt, and Martin Pera
Cross-sectional association between blood cholesterol and calcium levels in genetically diverse strains of mice., Cody M Cousineau, Kaelin Loftus, Gary Churchill, and Dave Bridges
Kdm1a safeguards the topological boundaries of PRC2-repressed genes and prevents aging-related euchromatinization in neurons., Beatriz Del Blanco, Sergio Niñerola, Ana M Martín-González, Juan Paraíso-Luna, Minji Kim, Rafael Muñoz-Viana, Carina Racovac, Jose V Sanchez-Mut, Yijun Ruan, and Ángel Barco
Into the Wild: A novel wild-derived inbred strain resource expands the genomic and phenotypic diversity of laboratory mouse models., Beth L Dumont, Daniel Mario Gatti, Mallory A Ballinger, Dana Lin, Megan Phifer-Rixey, Michael J Sheehan, Taichi A Suzuki, Lydia K Wooldridge, Hilda Opoku Frempong, Raman Akinyanju Lawal, Gary Churchill, Cathleen Lutz, Nadia Rosenthal, Jacqueline K White, and Michael W Nachman
Improving prenatal diagnosis through standards and aggregation., Michael H Duyzend, Pilar Cacheiro, Julius O B Jacobsen, Jessica Giordano, Harrison Brand, Ronald J Wapner, Michael E Talkowski, Peter N Robinson, and Damian Smedley
A team-based approach to cardiogenomic education., Emily A Edelman, Kalisi Logan, Therese Ingram, Kate Reed, Catherine Wicklund, Debra Duquette, and Lisa Dellefave-Castillo
Protocol for large DNA transgenesis in mice using the Cas9+Bxb1 toolbox., Valerie Erhardt, Chrystal M Snow, and Vishnu Hosur
Expression of ALS-PFN1 impairs vesicular degradation in iPSC-derived microglia., Salome Funes, Jonathan Jung, Del Hayden Gadd, Michelle Mosqueda, Jianjun Zhong, Shankaracharya, Matthew Unger, Karly Stallworth, Debra Cameron, Melissa S Rotunno, Pepper Dawes, Megan Fowler-Magaw, Pamela J Keagle, Justin A McDonough, Sivakumar Boopathy, Miguel Sena-Esteves, Jeffrey A Nickerson, Cathleen Lutz, William C Skarnes, Elaine T Lim, Dorothy P Schafer, Francesca Massi, John E Landers, and Daryl A Bosco
The Human Phenotype Ontology in 2024: phenotypes around the world., Michael Gargano, Nicolas Matentzoglu, Ben D Coleman, Eunice B Addo-Lartey, Anna V Anagnostopoulos, Joel Anderton, Paul Avillach, Anita M Bagley, Eduard Bakštein, James P Balhoff, Gareth Baynam, Susan M Bello, Michael Berk, Holli Bertram, Somer Bishop, Hannah Blau, David F Bodenstein, Pablo Botas, Kaan Boztug, Jolana Čady, Tiffany J Callahan, Rhiannon Cameron, Seth J Carbon, Francisco Castellanos, J Harry Caufield, Lauren E Chan, Christopher G Chute, Jaime Cruz-Rojo, Noémi Dahan-Oliel, Jon R Davids, Maud de Dieuleveult, Vinicius de Souza, Bert B A de Vries, Esther de Vries, J Raymond DePaulo, Beata Derfalvi, Ferdinand Dhombres, Claudia Diaz-Byrd, Alexander J M Dingemans, Bruno Donadille, Michael Duyzend, Reem Elfeky, Shahim Essaid, Carolina Fabrizzi, Giovanna Fico, Helen V Firth, Yun Freudenberg-Hua, Janice M Fullerton, Davera L Gabriel, Kimberly Gilmour, Jessica Giordano, Fernando S Goes, Rachel Gore Moses, Ian Green, Matthias Griese, Tudor Groza, Weihong Gu, Julia Guthrie, Benjamin Gyori, Ada Hamosh, Marc Hanauer, Kateřina Hanušová, Yongqun Oliver He, Harshad Hegde, Ingo Helbig, Kateřina Holasová, Charles Tapley Hoyt, Shangzhi Huang, Eric Hurwitz, Julius O B Jacobsen, Xiaofeng Jiang, Lisa Joseph, Kamyar Keramatian, Bryan King, Katrin Knoflach, David A Koolen, Megan L Kraus, Carlo Kroll, Maaike Kusters, Markus S Ladewig, David Lagorce, Meng-Chuan Lai, Pablo Lapunzina, Bryan Laraway, David Lewis-Smith, Xiarong Li, Caterina Lucano, Marzieh Majd, Mary L Marazita, Victor Martinez-Glez, Toby H McHenry, Melvin G McInnis, Julie A McMurry, Michaela Mihulová, Caitlin E Millett, Philip B Mitchell, Veronika Moslerová, Kenji Narutomi, Shahrzad Nematollahi, Julian Nevado, Andrew A Nierenberg, Nikola Novák Čajbiková, John I Nurnberger, Soichi Ogishima, Daniel Olson, Abigail Ortiz, Harry Pachajoa, Guiomar Perez de Nanclares, Amy Peters, Tim Putman, Christina K Rapp, Ana Rath, Justin Reese, Lauren Rekerle, Angharad M Roberts, Suzy Roy, Stephan J Sanders, Catharina Schuetz, Eva C Schulte, Thomas G Schulze, Martin Schwarz, Katie Scott, Dominik Seelow, Berthold Seitz, Yiping Shen, Morgan N Similuk, Eric S Simon, Balwinder Singh, Damian Smedley, Cynthia Smith, Jake T Smolinsky, Sarah Sperry, Elizabeth Stafford, Ray Stefancsik, Robin Steinhaus, Rebecca Strawbridge, Jagadish Chandrabose Sundaramurthi, Polina Talapova, Jair A Tenorio Castano, Pavel Tesner, Rhys H Thomas, Audrey Thurm, Marek Turnovec, Marielle E van Gijn, Nicole A Vasilevsky, Markéta Vlčková, Anita Walden, Kai Wang, Ron Wapner, James S Ware, Addo A Wiafe, Samuel A Wiafe, Lisa D Wiggins, Andrew E Williams, Chen Wu, Margot J Wyrwoll, Hui Xiong, Nefize Yalin, Yasunori Yamamoto, Lakshmi N Yatham, Anastasia K Yocum, Allan H Young, Zafer Yüksel, Peter P Zandi, Andreas Zankl, Ignacio Zarante, Miroslav Zvolský, Sabrina Toro, Leigh Carmody, Nomi L Harris, Monica C Munoz-Torres, Daniel Danis, Christopher J Mungall, Sebastian Köhler, Melissa A Haendel, and Peter N Robinson
RREB1 regulates neuronal proteostasis and the microtubule network., Emily N Griffin, Thomas Jucius, Su-Eon Sim, Belinda S. Harris, Sven Heinz, and Susan L Ackerman
An evaluation of GPT models for phenotype concept recognition., Tudor Groza, Harry Caufield, Dylan Gration, Gareth Baynam, Melissa A Haendel, Peter N Robinson, Christopher J Mungall, and Justin T Reese
Helper T cell immunity in humans with inherited CD4 deficiency., Antoine Guérin, Marcela Moncada-Vélez, Katherine Jackson, Masato Ogishi, Jérémie Rosain, Mathieu Mancini, David Langlais, Andrea Nunez, Samantha Webster, Jesse Goyette, Taushif Khan, Nico Marr, Danielle T Avery, Geetha Rao, Tim Waterboer, Birgitta Michels, Esmeralda Neves, Cátia Iracema Morais, Jonathan London, Stéphanie Mestrallet, Pierre Quartier Dit Maire, Bénédicte Neven, Franck Rapaport, Yoann Seeleuthner, Atar Lev, Amos J Simon, Jorge Montoya, Ortal Barel, Julio Gómez-Rodríguez, Julio C Orrego, Anne-Sophie L'Honneur, Camille Soudée, Jessica Rojas, Alejandra C Velez, Irini Sereti, Benjamin Terrier, Nancy Marin, Luis F García, Laurent Abel, Stéphanie Boisson-Dupuis, Joel Reis, Antonio Marinho, Andrea Lisco, Emilia Faria, Christopher C Goodnow, Julia Vasconcelos, Vivien Béziat, Cindy S Ma, Raz Somech, Jean-Laurent Casanova, Jacinta Bustamante, Jose Luis Franco, and Stuart G Tangye
Patient-Derived Models of Cancer in the NCI PDMC Consortium: Selection, Pitfalls, and Practical Recommendations., Amber N Habowski, Deepthi P Budagavi, Sandra D Scherer, Arin B Aurora, Giuseppina Caligiuri, William F Flynn, Ellen M Langer, Jonathan R Brody, Rosalie C Sears, Giorgia Foggetti, Anna Arnal Estape, Don X Nguyen, Katerina A Politi, Xiling Shen, David S Hsu, Donna M Peehl, John Kurhanewicz, Renuka Sriram, Milagros Suarez, Sophie Xiao, Yuchen Du, Xiao-Nan Li, Nora M Navone, Estefania Labanca, and Christopher D Willey
A serum-induced gene signature in hepatocytes is associated with pediatric nonalcoholic fatty liver disease., T Hang Nghiem-Rao, Jethro Johnson, Amy Pan, Samantha N Atkinson, Cynthia Behling, Pippa M Simpson, Mary L Holtz, George M. Weinstock, Jeffrey B Schwimmer, and Nita H Salzman
Astaxanthin and meclizine extend lifespan in UM-HET3 male mice; fisetin, SG1002 (hydrogen sulfide donor), dimethyl fumarate, mycophenolic acid, and 4-phenylbutyrate do not significantly affect lifespan in either sex at the doses and schedules used., David E Harrison, Randy Strong, Peter C. Reifsnyder, Nadia Rosenthal, Ron Korstanje, Elizabeth Fernandez, Kevin Flurkey, Brett C Ginsburg, Meredith D Murrell, Martin A Javors, Marisa Lopez-Cruzan, James F Nelson, Bradley J Willcox, Richard Allsopp, David M Watumull, David G Watumull, Gino Cortopassi, James L Kirkland, Tamar Tchkonia, Young Geun Choi, Matthew J Yousefzadeh, Paul D Robbins, James R Mitchell, Murat Acar, Ethan A Sarnoski, Michael R Bene, Adam Salmon, Navasuja Kumar, and Richard A Miller
Control of hippocampal synaptic plasticity by microglia-dendrite interactions depends on genetic context in mouse models of Alzheimer's disease., Sarah E Heuer, Kelly J Keezer, Amanda A Hewes, Kristen D. Onos, Kourtney Graham, Gareth R Howell, and Erik B Bloss
Genetic context drives age-related disparities in synaptic maintenance and structure across cortical and hippocampal neuronal circuits., Sarah E Heuer, Emily W Nickerson, Gareth R Howell, and Erik B Bloss
TTN truncation variants produce sarcomere-integrating proteins of uncertain functional significance., J Travis Hinson and Stuart G Campbell
Improved DNA Extraction and Amplification Strategy for 16S rRNA Gene Amplicon-Based Microbiome Studies., Bo-Young Hong, Mark Driscoll, Dawn Gratalo, Thomas Jarvie, and George M. Weinstock
Chapter 18 - Genetic modification of mice using CRISPR-Cas9: Best practices and practical concepts explained, Vishnu Hosur, Benjamin E. Low, and Michael V. Wiles
3D convolutional neural networks predict cellular metabolic pathway use from fluorescence lifetime decay data., Linghao Hu, Daniela De Hoyos, Yuanjiu Lei, A Phillip West, and Alex J Walsh
Microlearning: Evidence-based education that is effective for busy professionals and short attention spans., Therese Ingram, Emily A Edelman, Linda Steinmark, Kalisi Logan, and Kate Reed
Integrative analysis of RNA-sequencing and microarray for the identification of adverse effects of UVB exposure on human skin., Yujin Jang, Hye-Won Na, Dong Yeop Shin, Jun Lee, Jun Pyo Han, Hyun Soo Kim, Su Ji Kim, Eun-Jeong Choi, Charles Lee, Yong Deog Hong, Hyoung-June Kim, and Young Rok Seo
Inhibitory G proteins play multiple roles to polarize sensory hair cell morphogenesis., Amandine Jarysta, Abby Tadenev, Matthew Day, Barry Krawchuk, Benjamin E. Low, Michael V. Wiles, and Basile Tarchini
Data-driven modeling of core gene regulatory network underlying leukemogenesis in IDH mutant AML., Ataur Katebi, Xiaowen Chen, Daniel Ramirez, Sheng Li, and Mingyang Lu
Circulating Growth Differentiation Factors 11 and 8, Their Antagonists Follistatin and Follistatin-Like-3, and Risk of Heart Failure in Elders., Jorge R Kizer, Sheena Patel, Peter Ganz, Anne B Newman, Shalender Bhasin, Se-Jin Lee, Peggy M Cawthon, Nathan K LeBrasseur, Sanjiv J Shah, Bruce M Psaty, Russell P Tracy, and Steven R Cummings
Evaluation of Alginate Hydrogel Microstrands for Stromal Cell Encapsulation and Maintenance., Sujith Chander Reddy Kollampally, Xulang Zhang, Nicholas Moskwa, Deirdre A Nelson, Susan T Sharfstein, Melinda Larsen, and Yubing Xie
Genome-wide association study identifies human genetic variants associated with fatal outcome from Lassa fever., Dylan Kotliar, Siddharth Raju, Shervin Tabrizi, Ikponmwosa Odia, Augustine Goba, Mambu Momoh, John Demby Sandi, Parvathy Nair, Eric Phelan, Ridhi Tariyal, Philomena E Eromon, Samar Mehta, Refugio Robles-Sikisaka, Katherine J Siddle, Matt Stremlau, Simbirie Jalloh, Stephen K Gire, Sarah Winnicki, Bridget Chak, Stephen F Schaffner, Matthias Pauthner, Elinor K Karlsson, Sarah R Chapin, Sharon G Kennedy, Luis M Branco, Lansana Kanneh, Joseph J Vitti, Nisha Broodie, Adrianne Gladden-Young, Omowunmi Omoniwa, Pan-Pan Jiang, Nathan Yozwiak, Shannon Heuklom, Lina M Moses, George O Akpede, Danny A Asogun, Kathleen Rubins, Susan Kales, Anise N Happi, Christopher O Iruolagbe, Mercy Dic-Ijiewere, Kelly Iraoyah, Omoregie O Osazuwa, Alexander K Okonkwo, Stefan Kunz, Joseph B McCormick, S Humarr Khan, Anna N Honko, Eric S Lander, Michael B A Oldstone, Lisa Hensley, Onikepe A Folarin, Sylvanus A Okogbenin, Stephan Günther, Hanna M Ollila, Ryan Tewhey, Peter O Okokhere, John S Schieffelin, Kristian G Andersen, Steven K Reilly, Donald S Grant, Robert F Garry, Kayla G Barnes, Christian T Happi, and Pardis C Sabeti
NLGN4X TCR transgenic T cells to treat gliomas., Christoper Krämer, Michael Kilian, Yu-Chan Chih, Alexandros Kourtesakis, Dirk C Hoffmann, Tamara Boschert, Philipp Koopmann, Khwab Sanghvi, Alice De Roia, Stefanie Jung, Kristine Jähne, Bryan Day, Leonard D. Shultz, Miriam Ratliff, Richard Harbottle, Edward W Green, Rainer Will, Wolfgang Wick, Michael Platten, and Lukas Bunse
Imputation of 3D genome structure by genetic-epigenetic interaction modeling in mice., Lauren Kuffler, Daniel A Skelly, Anne M Czechanski, Haley J Fortin, Steven C. Munger, Christopher L. Baker, Laura G Reinholdt, and Gregory W. Carter
Multiple genetic loci influence vaccine-induced protection against Mycobacterium tuberculosis in genetically diverse mice., Sherry L Kurtz, Richard E Baker, Frederick J Boehm, Chelsea C Lehman, Lara R Mittereder, Hamda Khan, Amy P Rossi, Daniel M Gatti, Gillian Beamer, Christopher M Sassetti, and Karen L Elkins
Phenotypic similarity-based approach for variant prioritization for unsolved rare disease: a preliminary methodological report., David Lagorce, Emeline Lebreton, Leslie Matalonga, Oscar Hongnat, Maroua Chahdil, Davide Piscia, Ida Paramonov, Kornelia Ellwanger, Sebastian Köhler, Peter N Robinson, Holm Graessner, Sergi Beltran, Caterina Lucano, Marc Hanauer, and Ana Rath
Network-based analysis predicts interacting genetic modifiers from a meta-mapping study of spike-wave discharge in mice., Montana Kay Lara, Jeffrey L Brabec, Amanda E Hernan, Rod C Scott, Anna L. Tyler, and J Matthew Mahoney
Folate Deficiency and/or the Genetic Variant Mthfr(677C >T) Can Drive Hepatic Fibrosis or Steatosis in Mice, in a Sex-Specific Manner, Daniel Leclerc, Karen E Christensen, Alaina M Reagan, Vafa Keser, Yan Luan, Olga V Malysheva, Brandi Wasek, Teodoro Bottiglieri, Marie A Caudill, Gareth R Howell, and Rima Rozen
Stathmin-2 loss leads to neurofilament-dependent axonal collapse driving motor and sensory denervation., Jone López-Erauskin, Mariana Bravo-Hernandez, Maximiliano Presa, Michael W Baughn, Ze'ev Melamed, Melinda S Beccari, Ana Rita Agra de Almeida Quadros, Olatz Arnold-Garcia, Aamir Zuberi, Karen Ling, Oleksandr Platoshyn, Elkin Niño-Jara, I Sandra Ndayambaje, Melissa McAlonis-Downes, Larissa Cabrera, Jonathan W Artates, Jennifer L Ryan, Anita Hermann, John Ravits, C Frank Bennett, Paymaan Jafar-Nejad, Frank Rigo, Martin Marsala, Cathleen Lutz, Don W Cleveland, and Clotilde Lagier-Tourenne
The origin of genetic diversity of indigenous cockfighting chickens of Pakistan by analyzing the mtDNA., Sajid Mahmood, Mian Sayed Khan, Zaib Ullah, Raman Akinyanju Lawal, and Olivier Hanotte
Utility of long-read sequencing for All of Us., M Mahmoud, Y Huang, K Garimella, Peter A Audano, W Wan, N Prasad, R E Handsaker, S Hall, A Pionzio, M C Schatz, M E Talkowski, E E Eichler, S E Levy, and F J Sedlazeck
The Epigenetic Evolution of Glioma Is Determined by the IDH1 Mutation Status and Treatment Regimen., Tathiane M Malta, Thais S Sabedot, Natalia S Morosini, Indrani Datta, Luciano Garofano, Wies Vallentgoed, Frederick S Varn, Kenneth Aldape, Fulvio D'Angelo, Spyridon Bakas, Jill S Barnholtz-Sloan, Hui K Gan, Mohammad Hasanain, Ann-Christin Hau, Kevin C Johnson, Simona Cazacu, Ana C deCarvalho, Mustafa Khasraw, Emre Kocakavuk, Mathilde C M Kouwenhoven, Simona Migliozzi, Simone P Niclou, Johanna M Niers, D Ryan Ormond, Sun Ha Paek, Guido Reifenberger, Peter A Sillevis Smitt, Marion Smits, Lucy F Stead, Martin J van den Bent, Erwin G Van Meir, Annemiek Walenkamp, Tobias Weiss, Michael Weller, Bart A Westerman, Bauke Ylstra, Pieter Wesseling, Anna Lasorella, Pim J French, Laila M Poisson, Roel G W Verhaak, Antonio Iavarone, and Houtan Noushmehr
Sperm DNA methylation defects in a new mouse model of the 5,10-methylenetetrahydrofolate reductase 677C>T variant and correction with moderate dose folic acid supplementation., Edgar Martínez Duncker Rebolledo, Donovan Chan, Karen E Christensen, Alaina M Reagan, Gareth R Howell, Rima Rozen, and Jacquetta Trasler
The immunopathological landscape of human pre-TCRα deficiency: From rare to common variants., Marie Materna, Ottavia M Delmonte, Marita Bosticardo, Mana Momenilandi, Peyton E Conrey, Bénédicte Charmeteau-De Muylder, Clotilde Bravetti, Rebecca Bellworthy, Axel Cederholm, Frederik Staels, Christian A Ganoza, Samuel Darko, Samir Sayed, Corentin Le Floc'h, Masato Ogishi, Darawan Rinchai, Andrea Guenoun, Alexandre Bolze, Taushif Khan, Adrian Gervais, Renate Krüger, Mirjam Völler, Boaz Palterer, Mahnaz Sadeghi-Shabestari, Anne Langlois de Septenville, Chaim A Schramm, Sanjana Shah, John J Tello-Cajiao, Francesca Pala, Kayla Amini, Jose S Campos, Noemia Santana Lima, Daniel Eriksson, Romain Lévy, Yoann Seeleuthner, Soma Jyonouchi, Manar Ata, Fatima Al Ali, Anna Stittrich, Caroline Deswarte, Anaïs Pereira, Jérôme Mégret, Tom Le Voyer, Paul Bastard, Laureline Berteloot, Michaël Dussiot, Natasha Vladikine, Paula P Cardenas, Emmanuelle Jouanguy, Mashael Alqahtani, Amal Hasan, Thangavel Alphonse Thanaraj, Jérémie Rosain, Fahd Al Qureshah, Vito Sabato, Marie Alexandra Alyanakian, Marianne Leruez-Ville, Flore Rozenberg, Elie Haddad, Jose R Regueiro, Maria L Toribio, Judith R Kelsen, Mansoor Salehi, Shahram Nasiri, Mehdi Torabizadeh, Hassan Rokni-Zadeh, Majid Changi-Ashtiani, Nasimeh Vatandoost, Hossein Moravej, Seyed Mohammad Akrami, Mohsen Mazloomrezaei, Aurélie Cobat, Isabelle Meyts, Etsushi Toyofuku, Madoka Nishimura, Kunihiko Moriya, Tomoyuki Mizukami, Kohsuke Imai, Laurent Abel, Bernard Malissen, Fahd Al-Mulla, Fowzan Sami Alkuraya, Nima Parvaneh, Horst von Bernuth, Christian Beetz, Frédéric Davi, Daniel C Douek, Rémi Cheynier, David Langlais, Nils Landegren, Nico Marr, Tomohiro Morio, Mohammad Shahrooei, Rik Schrijvers, Sarah E Henrickson, Hervé Luche, Luigi D Notarangelo, Jean-Laurent Casanova, and Vivien Béziat
Protocol to assess bioenergetics and mitochondrial fuel usage in murine autoreactive immunocytes using the Seahorse Extracellular Flux Analyzer., Colleen L Mayberry, John J Wilson, Britney Sison, and Chih-Hao Chang
Bifunctional Inhibitor Reveals NEK2 as a Therapeutic Target and Regulator of Oncogenic Pathways in Lymphoma., Mason McCrury, Kennith Swafford, Sydnye L Shuttleworth, Syed Hassan Mehdi, Baku Acharya, Debasmita Saha, Kevin Naceanceno, Stephanie D Byrum, Aaron J Storey, Ying-Zhi Xu, Claire Doshier, Vijay Patel, Ginell R Post, Annick De Loose, Analiz Rodriguez, Leonard D. Shultz, Fenghuang Zhan, Donghoon Yoon, Brendan Frett, and Samantha Kendrick
Kinase-impaired BTK mutations are susceptible to clinical-stage BTK and IKZF1/3 degrader NX-2127., Skye Montoya, Jessie Bourcier, Mark Noviski, Hao Lu, Meghan C Thompson, Alexandra Chirino, Jacob Jahn, Anya K Sondhi, Stefan Gajewski, Ying Siow May Tan, Stephanie Yung, Aleksandra Urban, Eric Wang, Cuijuan Han, Xiaoli Mi, Won Jun Kim, Quinlan Sievers, Paul Auger, Hugo Bousquet, Nivetha Brathaban, Brandon Bravo, Melissa Gessner, Cristiana Guiducci, James N Iuliano, Tim Kane, Ratul Mukerji, Panga Jaipal Reddy, Janine Powers, Mateo Sanchez Garcia de Los Rios, Jordan Ye, Carla Barrientos Risso, Daniel Tsai, Gabriel Pardo, Ryan Q Notti, Alejandro Pardo, Maurizio Affer, Vindhya Nawaratne, Tulasigeri M Totiger, Camila Pena-Velasquez, Joanna M Rhodes, Andrew D Zelenetz, Alvaro Alencar, Lindsey E Roeker, Sanjoy Mehta, Ralph Garippa, Adam Linley, Rajesh Kumar Soni, Sigrid S Skånland, Robert J Brown, Anthony R Mato, Gwenn M Hansen, Omar Abdel-Wahab, and Justin Taylor
Human inherited CCR2 deficiency underlies progressive polycystic lung disease., Anna-Lena Neehus, Brenna Carey, Marija Landekic, Patricia Panikulam, Gail Deutsch, Masato Ogishi, Carlos A Arango-Franco, Quentin Philippot, Mohammadreza Modaresi, Iraj Mohammadzadeh, Melissa Corcini Berndt, Darawan Rinchai, Tom Le Voyer, Jérémie Rosain, Mana Momenilandi, Marta Martin-Fernandez, Taushif Khan, Jonathan Bohlen, Ji Eun Han, Alexandre Deslys, Mathilde Bernard, Tania Gajardo-Carrasco, Camille Soudée, Corentin Le Floc'h, Mélanie Migaud, Yoann Seeleuthner, Mi-Sun Jang, Eirini Nikolouli, Simin Seyedpour, Hugues Begueret, Jean-François Emile, Pierre Le Guen, Guido Tavazzi, Costanza Natalia Julia Colombo, Federico Capra Marzani, Micol Angelini, Francesca Trespidi, Stefano Ghirardello, Nasrin Alipour, Anne Molitor, Raphael Carapito, Mohsen Mazloomrezaei, Hassan Rokni-Zadeh, Majid Changi-Ashtiani, Chantal Brouzes, Pablo Vargas, Alessandro Borghesi, Nico Lachmann, Seiamak Bahram, Bruno Crestani, Susanta Pahari, Larry S Schlesinger, Nico Marr, Dusan Bugonovic, Stéphanie Boisson-Dupuis, Vivien Béziat, Laurent Abel, Raphael Borie, Lisa R Young, Robin Deterding, Mohammad Shahrooei, Nima Rezaei, Nima Parvaneh, Daniel Craven, Philippe Gros, Danielle Malo, Fernando E Sepulveda, Lawrence M Nogee, Nathalie Aladjidi, Bruce C Trapnell, Jean-Laurent Casanova, and Jacinta Bustamante
Unraveling the evolutionary origin of the complex Nuclear Receptor Element (cNRE), a cis-regulatory module required for preferential expression in the atrial chamber., Luana Nunes Santos, Ângela Maria Sousa Costa, Martin Nikolov, João E Carvalho, Allysson Coelho Sampaio, Frank E Stockdale, Gang Feng Wang, Hozana Andrade Castillo, Mariana Bortoletto Grizante, Stefanie Dudczig, Michelle Vasconcelos, Nadia Rosenthal, Patricia Regina Jusuf, Hieu T Nim, Paulo de Oliveira, Tatiana Guimarães de Freitas Matos, William Nikovits, Izabella Luisa Tambones, Ana Carolina Migliorini Figueira, Michael Schubert, Mirana Ramialison, and José Xavier-Neto
Mapping the metabolic responses to oxaliplatin-based chemotherapy with, Mariola Olkowicz, Khaled Ramadan, Hernando Rosales-Solano, Miao Yu, Aizhou Wang, Marcelo Cypel, and Janusz Pawliszyn
Randomized feature selection based semi-supervised latent Dirichlet allocation for microbiome analysis., Namitha Pais, Nalini Ravishanker, Sanguthevar Rajasekaran, George M. Weinstock, and Thi Dong Binh Tran
Proteomic Profiles of Human Arterioles Isolated From Fresh Adipose Tissue or Following Overnight Storage., Rajan Pandey, Michelle L Roberts, Jingli Wang, Michaela Pereckas, David Jensen, Andrew S Greene, Michael E Widlansky, and Mingyu Liang
Consensus and controversy in the management of paediatric and adult patients with ovarian immature teratoma: the Malignant Germ Cell International Consortium perspective., Farzana Pashankar, Matthew J Murray, Joanna J Gell, Nicola MacDonald, Jonathan Shamash, Deborah F Billmire, Lindsay Klosterkemper, Thomas Olson, Michelle S Hirsch, Michelle Lockley, Sara Stoneham, and A Lindsay Frazier
Sarcopenia and adipose tissue evaluation by artificial intelligence predicts the overall survival after TAVI., Matej Pekař, Otakar Jiravský, Jan Novák, Piotr Branny, Jakub Balušík, Daniel Danis, Jan Hečko, Marek Kantor, Robert Prosecky, Lubomir Blaha, and Radek Neuwirth
Targeting mitochondrial dysfunction using methylene blue or mitoquinone to improve skeletal aging., Sher Bahadur Poudel, Dorra Frikha-Benayed, Ryan R Ruff, Gozde Yildirim, Manisha Dixit, Ron Korstanje, Laura Robinson, Richard A Miller, David E Harrison, John R Strong, Mitchell B Schaffler, and Shoshana Yakar
The Monarch Initiative in 2024: an analytic platform integrating phenotypes, genes and diseases across species., Tim E Putman, Kevin Schaper, Nicolas Matentzoglu, Vincent P Rubinetti, Faisal S Alquaddoomi, Corey Cox, J Harry Caufield, Glass Elsarboukh, Sarah Gehrke, Harshad Hegde, Justin T Reese, Ian Braun, Richard M Bruskiewich, Luca Cappelletti, Seth Carbon, Anita R Caron, Lauren E Chan, Christopher G Chute, Katherina G Cortes, Vinícius De Souza, Tommaso Fontana, Nomi L Harris, Emily L Hartley, Eric Hurwitz, Julius O B Jacobsen, Madan Krishnamurthy, Bryan J Laraway, James A McLaughlin, Julie A McMurry, Sierra A T Moxon, Kathleen R Mullen, Shawn T O'Neil, Kent A Shefchek, Ray Stefancsik, Sabrina Toro, Nicole A Vasilevsky, Ramona L Walls, Patricia L Whetzel, David Osumi-Sutherland, Damian Smedley, Peter N Robinson, Christopher J Mungall, Melissa A Haendel, and Monica C Munoz-Torres
A single-cell time-lapse of mouse prenatal development from gastrula to birth., Chengxiang Qiu, Beth K Martin, Ian C Welsh, Riza M Daza, Truc-Mai Le, Xingfan Huang, Eva K Nichols, Megan L Taylor, Olivia Fulton, Diana R O'Day, Anne Roshella Gomes, Saskia Ilcisin, Sanjay Srivatsan, Xinxian Deng, Christine M Disteche, William Stafford Noble, Nobuhiko Hamazaki, Cecilia B Moens, David Kimelman, Junyue Cao, Alexander F Schier, Malte Spielmann, Stephen A. Murray, Cole Trapnell, and Jay Shendure
Murine MHC-Deficient Nonobese Diabetic Mice Carrying Human HLA-DQ8 Develop Severe Myocarditis and Myositis in Response to Anti-PD-1 Immune Checkpoint Inhibitor Cancer Therapy., Jeremy Racine, John F Bachman, Ji-Gang Zhang, Adel Misherghi, Raheem Khadour, Sana Kaisar, Olivia Bedard, Catherine Jenkins, Annie Abbott, Elvira Forte, Peter Rainer, Nadia Rosenthal, Susanne Sattler, and David V. Serreze
In vivo activity of the second-generation proteasome inhibitor ixazomib against pediatric T-cell acute lymphoblastic leukemia xenografts., Joanna Randall, Kathryn Evans, Ben Watts, Hansen J Kosasih, Christopher M Smith, Eric J Earley, Stephen W Erickson, Emily L Jocoy, Carol J Bult, Beverly A Teicher, Charles E de Bock, Malcolm A Smith, and Richard B Lock
Distinct baseline immune characteristics associated with responses to conjugated and unconjugated pneumococcal polysaccharide vaccines in older adults., Sathyabaarathi Ravichandran, Fernando Erra-Diaz, Emin Onur Karakaslar, Radu Marches, Lisa Kenyon-Pesce, Robert J Rossi, Damien Chaussabel, Djamel Nehar-Belaid, David C LaFon, Virginia Pascual, Karolina Palucka, Silke Paust, Moon H Nahm, George A Kuchel, Jacques Banchereau, and Duygu Ucar
Boosting BDNF in muscle rescues impaired axonal transport in a mouse model of DI-CMTC peripheral neuropathy., Elena R Rhymes, Rebecca L Simkin, Ji Qu, David Villarroel-Campos, Sunaina Surana, Yao Tong, Ryan Shapiro, Robert W. Burgess, Xiang-Lei Yang, Giampietro Schiavo, and James N Sleigh
A data browsing application for accessing gene and module-level blood transcriptome profiles of healthy pregnant women from high- and low-resource settings., Darawan Rinchai, Tobias Brummaier, Alexandra A Marr, Tanwir Habib, Mohammed Toufiq, Tomoshigue Kino, François Nosten, Souhaila Al Khodor, Annalisa Terranegra, Rose McGready, Basirudeen Syed Ahamed Kabeer, and Damien Chaussabel
Toward robust clinical genome interpretation: Developing a consistent terminology to characterize Mendelian disease-gene relationships-allelic requirement, inheritance modes, and disease mechanisms., Angharad M Roberts, Marina T DiStefano, Erin Rooney Riggs, Katherine S Josephs, Fowzan S Alkuraya, Joanna Amberger, Mutaz Amin, Jonathan S Berg, Fiona Cunningham, Karen Eilbeck, Helen V Firth, Julia Foreman, Ada Hamosh, Eleanor Hay, Sarah Leigh, Christa L Martin, Ellen M McDonagh, Daniel Perrett, Erin M Ramos, Peter N Robinson, Ana Rath, David W Sant, Zornitza Stark, Nicola Whiffin, Heidi L Rehm, and James S Ware
Discovery and validation of genes driving drug-intake and related behavioral traits in mice., Tyler A. Roy, Jason A. Bubier, Price E Dickson, Troy Wilcox, Juliet Ndukum, James Clark, S J Sukoff Rizzo, John C Crabbe, James M. Denegre, Karen L. Svenson, Robert E Braun, Vivek Kumar, Stephen A. Murray, Jacqueline K White, Vivek M. Philip, and Elissa J Chesler
Large structural variants in KOLF2.1J are unlikely to compromise neurological disease modeling., Mallory Ryan, Justin A McDonough, Michael E Ward, Mark R Cookson, William C Skarnes, and Florian T Merkle
Information-theory analysis of mouse string-pulling agrees with Fitts's Law: Increasing task difficulty engages multiple sensorimotor modalities in a dual oscillator behavior., Pardeepak S Sandhu, Behroo Mirza Agha, Samsoon Inayat, Surjeet Singh, Hardeep S Ryait, Majid H Mohajerani, and Ian Q Whishaw
Transcriptional and functional consequences of Oncostatin M signaling on young Dnmt3a-mutant hematopoietic stem cells., Logan S Schwartz, Kira Young, Timothy M Stearns, Nathan Boyer, Kristina D Mujica, and Jennifer J. Trowbridge
Learning from conect4children: A Collaborative Approach towards Standardisation of Disease-Specific Paediatric Research Data, Anando Sen, Victoria Hedley, Eva Degraeuwe, Steven Hirschfeld, Ronald Cornet, Ramona Walls, John Owen, Peter N Robinson, Edward G. Neilan, Thomas Liener, Giovanni Nisato, Neena Modi, Simon Woodworth, Avril Palmeri, Ricarda Gaentzsch, Melissa Walsh, Teresa Berkery, Joanne Lee, Laura Persijn, Kasey Baker, Kristina An Haack, Sonia Segovia Simon, Julius O. B. Jacobsen, Giorgio Reggiardo, Melissa A. Kirwin, Jessie Trueman, Claudia Pansieri, Donato Bonifazi, Sinéad Nally, Fedele Bonifazi, Rebecca Leary, and Volker Straub
A machine learning approach for quantifying age-related histological changes in the mouse kidney., Susan Sheehan, Seamus Mawe, Mandy Chen, Jenna Klug, Warren Ladiges, Ron Korstanje, and J Matthew Mahoney
Genetic diversity promotes resilience in a mouse model of Alzheimer's disease., Neelakshi Soni, Lindsay A Hohsfield, Kristine M Tran, Shimako Kawauchi, Amber Walker, Dominic Javonillo, Jimmy Phan, Dina Matheos, Celia Da Cunha, Asli Uyar, Giedre Milinkeviciute, Angela Gomez-Arboledas, Katelynn Tran, Catherine C Kaczorowski, Marcelo A Wood, Andrea J Tenner, Frank M LaFerla, Gregory W. Carter, Ali Mortazavi, Vivek Swarup, Grant R MacGregor, and Kim N Green
A host-microbiota interactome reveals extensive transkingdom connectivity., Nicole D Sonnert, Connor E Rosen, Andrew R Ghazi, Eric A Franzosa, Brianna Duncan-Lowey, Jaime A González-Hernández, John D Huck, Yi Yang, Yile Dai, Tyler A Rice, Mytien T Nguyen, Deguang Song, Yiyun Cao, Anjelica L Martin, Agata A Bielecka, Suzanne Fischer, Changhui Guan, Julia Oh, Curtis Huttenhower, Aaron M Ring, and Noah W Palm
IDHwt glioblastomas can be stratified by their transcriptional response to standard treatment, with implications for targeted therapy., Georgette Tanner, Rhiannon Barrow, Shoaib Ajaib, Muna Al-Jabri, Nazia Ahmed, Steven Pollock, Martina Finetti, Nora Rippaus, Alexander F Bruns, Khaja Syed, James A Poulter, Laura Matthews, Thomas Hughes, Erica Wilson, Colin Johnson, Frederick S Varn, Anke Brüning-Richardson, Catherine Hogg, Alastair Droop, Arief Gusnanto, Matthew A Care, Luisa Cutillo, David R Westhead, Susan C Short, Michael D Jenkinson, Andrew Brodbelt, Aruna Chakrabarty, Azzam Ismail, Roel G W Verhaak, and Lucy F Stead
New directions for Alzheimer's disease research from the Jackson Laboratory Center for Alzheimer's and Dementia Research 2022 workshop., Maria Telpoukhovskaia, Thomas J Murdy, Olivia J Marola, Kevin Charland, Michael MacLean, Tain Luquez, Alexandra M Lish, Sarah Neuner, Amy R Dunn, Kristen D. Onos, Jesse Wiley, Derek Archer, Matthew J Huentelman, Matthias Arnold, Vilas Menon, Alison Goate, Linda J Van Eldik, Paul R Territo, Gareth R Howell, Gregory W. Carter, Kristen M S O'Connell, Catherine Kaczorowski, and the 2022 JAX CADR Workshop
CAGI, the Critical Assessment of Genome Interpretation, establishes progress and prospects for computational genetic variant interpretation methods., The Critical Assessment of Genome Interpretation Consortium
Activity-dependent compartmentalization of dendritic mitochondria morphology through local regulation of fusion-fission balance in neurons in vivo., Daniel M Virga, Stevie Hamilton, Bertha Osei, Abigail Morgan, Parker Kneis, Emiliano Zamponi, Natalie J Park, Victoria L Hewitt, David Zhang, Kevin C Gonzalez, Fiona M Russell, D Grahame Hardie, Julien Prudent, Erik B Bloss, Attila Losonczy, Franck Polleux, and Tommy L Lewis
Transcriptome analysis reveals organ-specific effects of 2-deoxyglucose treatment in healthy mice., Ann E Wells, John J Wilson, Sarah E Heuer, John D Sears, Jian Wei, Raghav Pandey, Mauro W Costa, Catherine Kaczorowski, Derry C. Roopenian, Chih-Hao Chang, and Gregory W. Carter
TREX tetramer disruption alters RNA processing necessary for corticogenesis in THOC6 Intellectual Disability Syndrome., Elizabeth A Werren, Geneva R LaForce, Anshika Srivastava, Delia R Perillo, Shaokun Li, Katherine Johnson, Safa Baris, Brandon Berger, Samantha L Regan, Christian D Pfennig, Sonja de Munnik, Rolph Pfundt, Malavika Hebbar, Raúl Jimenez-Heredia, Elif Karakoc-Aydiner, Ahmet Ozen, Jasmin Dmytrus, Ana Krolo, Ken Corning, E J Prijoles, Raymond J Louie, Robert Roger Lebel, Thuy-Linh Le, Jeanne Amiel, Christopher T Gordon, Kaan Boztug, Katta M Girisha, Anju Shukla, Stephanie L Bielas, and Ashleigh E Schaffer
Contributions of mouse genetic strain background to age-related phenotypes in physically active HET3 mice., Jake W Willows, Zahra Alshahal, Naeemah M Story, Michele J Alves, Pablo Vidal, Hallie Harris, Rochelle Rodrigo, Kristin I Stanford, Juan Peng, Peter C. Reifsnyder, David E Harrison, W David Arnold, and Kristy L Townsend
Multicenter integrated analysis of noncoding CRISPRi screens., David Yao, Josh Tycko, Jin Woo Oh, Lexi R Bounds, Sager J Gosai, Lazaros Lataniotis, Ava Mackay-Smith, Benjamin R Doughty, Idan Gabdank, Henri Schmidt, Tania Guerrero-Altamirano, Keith Siklenka, Katherine Guo, Alexander D White, Ingrid Youngworth, Kalina Andreeva, Xingjie Ren, Alejandro Barrera, Yunhai Luo, Galip Gürkan Yardımcı, Ryan Tewhey, Anshul Kundaje, William J Greenleaf, Pardis C Sabeti, Christina Leslie, Yuri Pritykin, Jill E Moore, Michael A Beer, Charles A Gersbach, Timothy E Reddy, Yin Shen, Jesse M Engreitz, Michael C Bassik, and Steven K Reilly
Mucosal-associated invariant T cells in cancer: dual roles, complex interactions and therapeutic potential., Mesut Yigit, Omer Faruk Basoglu, and Derya Unutmaz