Submissions from 2024
IL3-Driven T Cell-Basophil Crosstalk Enhances Antitumor Immunity., Jian Wei, Colleen L Mayberry, Xiaoting Lv, Fangyan Hu, Taushif Khan, Natalie A Logan, John J Wilson, John D Sears, Damien Chaussabel, and Chih-Hao Chang
Transcriptome analysis reveals organ-specific effects of 2-deoxyglucose treatment in healthy mice., Ann E Wells, John J Wilson, Sarah E Heuer, John D Sears, Jian Wei, Raghav Pandey, Mauro W Costa, Catherine Kaczorowski, Derry C. Roopenian, Chih-Hao Chang, and Gregory W. Carter
TREX tetramer disruption alters RNA processing necessary for corticogenesis in THOC6 Intellectual Disability Syndrome., Elizabeth A Werren, Geneva R LaForce, Anshika Srivastava, Delia R Perillo, Shaokun Li, Katherine Johnson, Safa Baris, Brandon Berger, Samantha L Regan, Christian D Pfennig, Sonja de Munnik, Rolph Pfundt, Malavika Hebbar, Raúl Jimenez-Heredia, Elif Karakoc-Aydiner, Ahmet Ozen, Jasmin Dmytrus, Ana Krolo, Ken Corning, E J Prijoles, Raymond J Louie, Robert Roger Lebel, Thuy-Linh Le, Jeanne Amiel, Christopher T Gordon, Kaan Boztug, Katta M Girisha, Anju Shukla, Stephanie L Bielas, and Ashleigh E Schaffer
Biallelic variants in CSMD1 are implicated in a neurodevelopmental disorder with intellectual disability and variable cortical malformations., Elizabeth A Werren, Emily R Peirent, Henna Jantti, Alba Guxholli, Kinshuk Raj Srivastava, Naama Orenstein, Vinodh Narayanan, Wojciech Wiszniewski, Mateusz Dawidziuk, Pawel Gawlinski, Muhammad Umair, Amjad Khan, Shahid Niaz Khan, David Geneviève, Daphné Lehalle, K L I van Gassen, Jacques C Giltay, Renske Oegema, Richard H van Jaarsveld, Rafiullah Rafiullah, Gudrun A Rappold, Rachel Rabin, John G Pappas, Marsha M Wheeler, Michael J Bamshad, Yao-Chang Tsan, Matthew B Johnson, Catherine E Keegan, Anshika Srivastava, and Stephanie L Bielas
A Pan-Cancer Patient-Derived Xenograft Histology Image Repository with Genomic and Pathologic Annotations Enables Deep Learning Analysis, Brian S White, Xing Yi Woo, Soner Koc, Todd B Sheridan, Steven Neuhauser, Shidan Wang, Yvonne A. Evrard, Li Chen, Ali Foroughi Pour, John D. Landua, R Jay Mashl, Sherri R. Davis, Bingliang Fang, Maria Gabriela Rosa, Kurt W. Evans, Matthew H. Bailey, Yeqing Chen, Min Xiao, Jill C Rubinstein, Brian J Sanderson, Michael W Lloyd, Sergii Domanskyi, Lacey E. Dobrolecki, Maihi Fujita, Junya Fujimoto, Guanghua Xiao, Ryan C. Fields, Jacqueline L. Mudd, Xiaowei Xu, Melinda G. Hollingshead, Shahanawaz Jiwani, Saul Acevedo, PDXNet Consortium, Brandi N. Davis-Dusenbery, Peter N Robinson, Jeffrey A. Moscow, James H. Doroshow, Nicholas Mitsiades, Salma Kaochar, Chong-xian Pan, Luis G. Caravajal-Carmona, Alana L. Welm, Bryan E. Welm, Ramaswamy Govindan, Shunqiang Li, Michael A. Davies, Jack A. Roth, Funda Meric-Bernstam, Yang Xie, Meenhard Herlyn, Li Ding, Michael T. Lewis, Carol J Bult, Dennis A. Dean II, and Jeffrey Chuang
Contributions of mouse genetic strain background to age-related phenotypes in physically active HET3 mice., Jake W Willows, Zahra Alshahal, Naeemah M Story, Michele J Alves, Pablo Vidal, Hallie Harris, Rochelle Rodrigo, Kristin I Stanford, Juan Peng, Peter C. Reifsnyder, David E Harrison, W David Arnold, and Kristy L Townsend
Synthetic BZLF1-targeted transcriptional activator for efficient lytic induction therapy against EBV-associated epithelial cancers., Man Wu, Pok Man Hau, Linxian Li, Chi Man Tsang, Yike Yang, Aziz Taghbalout, Grace Tin-Yun Chung, Shin Yee Hui, Wing Chung Tang, Nathaniel L. Jillette, Jacqueline Jufen Zhu, Horace Hok Yeung Lee, Ee Ling Kong, Melissa Sue Ann Chan, Jason Ying Kuen Chan, Brigette Buig Yue Ma, Mei-Ru Chen, Charles Lee, Ka Fai To, Albert Cheng, and Kwok-Wai Lo
Adducin Regulates Sarcomere Disassembly During Cardiomyocyte Mitosis., Feng Xiao, Ngoc Uyen Nhi Nguyen, Ping Wang, Shujuan Li, Ching-Cheng Hsu, Suwannee Thet, Wataru Kimura, Xiang Luo, Nicholas T Lam, Ivan Menendez-Montes, Waleed M Elhelaly, Alisson Campos Cardoso, Ana Helena Macedo Pereira, Rohit Singh, Sakthivel Sadayappan, Mohammed Kanchwala, Chao Xing, Feria A Ladha, J Travis Hinson, Roger J Hajjar, Joseph A Hill, and Hesham A Sadek
Multicenter integrated analysis of noncoding CRISPRi screens., David Yao, Josh Tycko, Jin Woo Oh, Lexi R Bounds, Sager J Gosai, Lazaros Lataniotis, Ava Mackay-Smith, Benjamin R Doughty, Idan Gabdank, Henri Schmidt, Tania Guerrero-Altamirano, Keith Siklenka, Katherine Guo, Alexander D White, Ingrid Youngworth, Kalina Andreeva, Xingjie Ren, Alejandro Barrera, Yunhai Luo, Galip Gürkan Yardımcı, Ryan Tewhey, Anshul Kundaje, William J Greenleaf, Pardis C Sabeti, Christina Leslie, Yuri Pritykin, Jill E Moore, Michael A Beer, Charles A Gersbach, Timothy E Reddy, Yin Shen, Jesse M Engreitz, Michael C Bassik, and Steven K Reilly
Mucosal-associated invariant T cells in cancer: dual roles, complex interactions and therapeutic potential., Mesut Yigit, Omer Faruk Basoglu, and Derya Unutmaz
A cochlear progenitor pool influences patterning of the mammalian sensory epithelium via MYBL2., Caryl A Young, Emily Burt, and Vidhya Munnamalai
Variation in mesenchymal KITL/SCF and IGF1 expression in middle age underlies steady-state hematopoietic stem cell aging., Kira Young, Maria Telpoukhovskaia, Johanna Hofmann, Jayna J Mistry, Konstantinos D Kokkaliaris, and Jennifer J. Trowbridge
Engraftment of adult hematopoietic stem and progenitor cells in a novel model of humanized mice., Chun I. Yu, Richard S. Maser, Florentina Marches, Jacques Banchereau, and Karolina Palucka
Protocol to construct humanized mice with adult CD34, Chun I. Yu, Richard S. Maser, Florentina Marches, Jacques Banchereau, and Karolina Palucka
Active Molecular Network Discovery Links Lifestyle Variables to Breast Cancer in the Long Island Breast Cancer Study Project., Miao Yu, Qian Li, Georgia Dolios, Peijun Tu, Susan Teitelbaum, Jia Chen, and Lauren Petrick
Metabolic fitness of IgA(+) plasma cells in the gut requires DOCK8, Biyan Zhang, Shuting Chen, Xiangyun Yin, Caleb D McBride, Jake A Gertie, Marina Yurieva, Agata A Bielecka, Brian Hoffmann, J Travis Hinson, Jessica D S Grassmann, Lan Xu, Emily R Siniscalco, Arielle Soldatenko, Laura Hoyt, Julie Joseph, Elizabeth B Norton, Gowthaman Uthaman, Noah W Palm, Elise Liu, Stephanie C Eisenbarth, and Adam Williams
Transcription factor AP-2 gamma affects porcine early embryo development by regulating epigenetic modification., Daoyu Zhang, Di Wu, Sheng Zhang, Meng Zhang, Yongfeng Zhou, Xinglan An, Qi Li, and Ziyi Li
Per- and polyfluoroalkyl substances (PFAS) and cancer: Detection methodologies, epidemiological insights, potential carcinogenic mechanisms, and future perspectives., Jie Zheng, Sheng Liu, Junjie Yang, Shujian Zheng, and Boshi Sun
Longitudinal profiling of the microbiome at four body sites reveals core stability and individualized dynamics during health and disease., Xin Zhou, Xiaotao Shen, Jethro Johnson, Daniel Spakowicz, Melissa Agnello, Wenyu Zhou, Monica Avina, Alexander Honkala, Faye Chleilat, Shirley Jingyi Chen, Kexin Cha, Shana Leopold, Chenchen Zhu, Lei Chen, Lin Lyu, Daniel Hornburg, Si Wu, Xinyue Zhang, Chao Jiang, Liuyiqi Jiang, Lihua Jiang, Ruiqi Jian, Andrew W Brooks, Meng Wang, Kévin Contrepois, Peng Gao, Sophia Miryam Schüssler-Fiorenza Rose, Thi Dong Binh Tran, Hoan Nguyen, Alessandra Celli, Bo-Young Hong, Eddy J Bautista, Yair Dorsett, Paula B Kavathas, Yanjiao Zhou, Erica Sodergren Weinstock, George M. Weinstock, and Michael P Snyder
TRPM2 enhances ischemic excitotoxicity by associating with PKCγ., Pengyu Zong, Jianlin Feng, Nicholas Legere, Yunfeng Li, Zhichao Yue, Cindy X Li, Yasuo Mori, Barbara Miller, Bing Hao, and Lixia Yue
Submissions from 2023
Lipophilic analogues of D-cysteine prevent and reverse physical dependence to fentanyl in male rats., James N Bates, Paulina M Getsy, Gregory A Coffee, Santhosh M Baby, Peter M MacFarlane, Yee-Hsee Hsieh, Zackery T Knauss, Jason A. Bubier, Devin Mueller, and Stephen J Lewis
Levetiracetam modulates brain metabolic networks and transcriptomic signatures in the 5XFAD mouse model of Alzheimer's disease., Charles P Burton, Evgeny J Chumin, Alyssa Y Collins, Scott A Persohn, Kristen D. Onos, Ravi S Pandey, Sara K Quinney, and Paul R Territo
Hematopoietic Stem Cells and Metabolic Deterioration in Alström Syndrome, a Rare Genetic Model of the Metabolic Syndrome., Francesca Dassie, Mattia Albiero, Silvia Bettini, Roberta Cappellari, Gabriella Milan, Stefano Ciciliot, Juergen K. Naggert, Angelo Avogaro, Roberto Vettor, Pietro Maffei, and Gian Paolo Fadini
Whole-genome long-read sequencing downsampling and its effect on variant-calling precision and recall., William T Harvey, Peter Ebert, Jana Ebler, Peter A Audano, Katherine M Munson, Kendra Hoekzema, David Porubsky, Christine R Beck, Tobias Marschall, Kiran Garimella, and Evan E Eichler
3D bioengineered neural tissue generated from patient-derived iPSCs mimics time-dependent phenotypes and transcriptional features of Alzheimer's disease., Selene Lomoio, Ravi S Pandey, Nicolas Rouleau, Beatrice Menicacci, WonHee Kim, William L Cantley, Philip G Haydon, David A Bennett, Tracy L Young-Pearse, Gregory W. Carter, David L Kaplan, and Giuseppina Tesco
Genomic medicine year in review: 2023., Teri A Manolio, Jahnavi Narula, Carol J Bult, Rex L Chisholm, Patricia A Deverka, Geoffrey S Ginsburg, Eric D Green, Gillian Hooker, Gail P Jarvik, George A Mensah, Erin M Ramos, Dan M Roden, Robb Rowley, and Marc S Williams
HLA-DQ8 Supports Development of Insulitis Mediated by Insulin-Reactive Human TCR-Transgenic T Cells in Nonobese Diabetic Mice., Jeremy Racine, Adel Misherghi, Jennifer R Dwyer, Richard S. Maser, Elvira Forte, Olivia Bedard, Susanne Sattler, Alberto Pugliese, Laurie Landry, Colleen Elso, Maki Nakayama, Stuart Mannering, Nadia Rosenthal, and David V. Serreze
Application of a gene modular approach for clinical phenotype genotype association and sepsis prediction using machinApplication of a gene modular approach for clinical phenotype genotype association and sepsis prediction using machine learning in meningococcal sepsise learning in meningococcal sepsis, Asrar Rashid, Arif Anwary, Feras Al-Obeidat, Joe Brierley, Mohammed Uddin, Hoda Alkhzaimi, Amrita Sarpal, Mohammed Toufiq, Zainab Malik, Raziya Kadwa, Praveen Khilnani, M Guftar Shaikh, Govind Benakatti, Javed Sharief, Syed Ahmed Zaki, Abdulrahman Zeyada, Ahmed Al-Dubai, Wael Hafez, and Amir Hussain
Unveiling the dynamics of the breast milk microbiome: impact of lactation stage and gestational age., Parul Singh, Noora Al Mohannadi, Selvasankar Murugesan, Fajr Almarzooqi, Basirudeen Syed Ahamed Kabeer, Alexandra Katharina Marr, Tomoshige Kino, Tobias Brummaier, Annalisa Terranegra, Rose McGready, François Nosten, Damien Chaussabel, and Souhaila Al Khodor
De novo, Jagadish Chandrabose Sundaramurthi, Anita M Bagley, Hannah Blau, Leigh Carmody, Amy Crandall, Daniel Danis, Michael Gargano, Anxhela Gjyshi Gustafson, Ellen M Raney, Mallory Shingle, Jon R Davids, and Peter N Robinson
MouseScholar: Evaluating an Image+Text Search System for Biocuration, Juan Trelles Trabucco