Document Type

Article

Publication Date

8-15-2026

Keywords

Humans, Animals, SOX Transcription Factors, Sex Determination Processes

JAX Source

Biol Open. 2026 Aug 15;15(8):bio062466.

ISSN

2046-6390

PMID

42572838

DOI

https://doi.org/10.1242/bio.062466

Abstract

Marking the 20th anniversary of a well-established meeting series focused on the biological and clinical importance of SOX genes as regulators of cell fate, the 7th International Workshop on SOX Transcription Factors held from 8-11 September 2025 at the Prince Resort MICE Karuizawa in Nagano, Japan, brought together 83 participants from 17 countries. The meeting showcased the foundations of SOX gene research and recent technological and conceptual breakthroughs across diverse model systems and human research, illustrating the field's evolution and emerging directions for future research. Reflecting the breadth of SOX biology - from early embryonic development and sex determination to pathogenesis and sex testing policies in sports - this Meeting Review highlights the key scientific advances and messages presented at the meeting to encourage and inspire researchers in the field of SOX biology.

Creative Commons License

Creative Commons Attribution 4.0 International License
This work is licensed under a Creative Commons Attribution 4.0 International License.

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