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Submissions from 2002

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Lipid metabolome-wide effects of the PPARgamma agonist rosiglitazone., S M. Watkins, P R. Reifsnyder, H J. Pan, J B. German, and E H. Leiter

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Absence of the CD44 Gene Prevents Sarcoma Metastasis., G F. Weber, R T. Bronson, J Ilagan, H Cantor, R Schmits, and T W. Mak

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Mouse genetic model for bone strength and size phenotypes: NZB/B1NJ and RF/J inbred strains., J E. Wergedal, M H. Sheng, Bicknell C. Ackert, W G. Beamer, and D J. Baylink

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Identification of quantitative trait loci for chemical/inflammatory nociception in mice., S G. Wilson, E J. Chesler, H Hain, A J. Rankin, J Z. Schwarz, S B. Call, M R. Murray, E E. West, C Teuscher, Zas S. Rodriguez, J K. Belknap, and J S. Mogil

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Interacting QTLs for cholesterol gallstones and gallbladder mucin in AKR and SWR strains of mice., H Wittenburg, F Lammert, D Q. Wang, G A. Churchill, R Li, G Bouchard, M C. Carey, and B Paigen

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Circulating levels of IGF-1 directly regulate bone growth and density., S Yakar, C J. Rosen, W G. Beamer, Bicknell C. Ackert, Y Wu, J L. Liu, G T. Ooi, J Setser, J Frystyk, Y R. Boisclair, and D LeRoith

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Tumor suppression by a severely truncated species of retinoblastoma protein., H Yang, B O. Williams, P W. Hinds, T S. Shih, T Jacks, R T. Bronson, and D M. Livingston

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Fierce: a new mouse deletion of Nr2e1; violent behaviour and ocular abnormalities are background-dependent., K A. Young, M L. Berry, C L. Mahaffey, J R. Saionz, N L. Hawes, B Chang, Q Y. Zheng, R S. Smith, R T. Bronson, R J. Nelson, and E M. Simpson

Modulation of the notch signaling by Mash1 and Dlx1/2 regulates sequential specification and differentiation of progenitor cell types in the subcortical telencephalon., K Yun, S Fischman, J Johnson, d e. Hrabe, G Weinmaster, and J L. Rubenstein

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Segmentation defects of Notch pathway mutants and absence of a synergistic phenotype in lunatic fringe/radical fringe double mutant mice., N Zhang, C R. Norton, and T Gridley

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Slug is a novel downstream target of MyoD. Temporal profiling in muscle regeneration., P Zhao, S Iezzi, E Carver, D Dressman, T Gridley, V Sartorelli, and E P. Hoffman

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Vitamin D(3) receptor ablation sensitizes skin to chemically induced tumorigenesis., G M. Zinser, J P. Sundberg, and J Welsh

Submissions from 2001

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Changing patterns of cell surface mono (ADP-ribosyl) transferase antigen ART2.2 on resting versus cytopathically-activated T cells in NOD/Lt mice., V Ablamunits, M Bridgett, T Duffy, F Haag, M Nissen, Nolte F. Koch, and E H. Leiter

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CD40-mediated activation of T cells accelerates, but is not required for, encephalitogenic potential of myelin basic protein-recognizing T cells in a model of progressive experimental autoimmune encephalomyelitis., Leeman S. Abromson, E Maverakis, R Bronson, and M E. Dorf

Intercellular communication via connexin43 gap junctions is required for ovarian folliculogenesis in the mouse., C L. Ackert, J E. Gittens, M J. O'Brien, J J. Eppig, and G M. Kidder

Mitotic chromosome preparations from mouse cells for karyotyping., E C. Akeson and M T. Davisson

Ts65Dn -- localization of the translocation breakpoint and trisomic gene content in a mouse model for Down syndrome., E C. Akeson, J P. Lambert, S Narayanswami, K Gardiner, L J. Bechtel, and M T. Davisson

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Efficient chromosomal mapping of a methylcholanthrene- induced tumor antigen by ctl immunoselection., S Akilesh, M E. Dudley, P A. Eden, and D C. Roopenian

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The mouse Ames waltzer hearing-loss mutant is caused by mutation of Pcdh15, a novel protocadherin gene., K N. Alagramam, C L. Murcia, H Y. Kwon, K S. Pawlowski, C G. Wright, and R P. Woychik

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Mutations in the novel protocadherin PCDH15 cause Usher syndrome type 1F., K N. Alagramam, H Yuan, M H. Kuehn, C L. Murcia, S Wayne, C R. Srisailpathy, R B. Lowry, R Knaus, Laer L. Van, F P. Bernier, S Schwartz, C Lee, C C. Morton, R F. Mullins, A Ramesh, Camp G. Van, G S. Hageman, R P. Woychik, R J. Smith, and G S. Hagemen

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Evidence that Sry is expressed in pre-Sertoli cells and Sertoli and granulosa cells have a common precursor., K H. Albrecht and E M. Eicher

Transgenic and knockout databases. Behavioral profiles of mouse mutants., A V. Anagnostopoulos, L E. Mobraaten, J J. Sharp, and M T. Davisson

Availability and characterization of transgenic and knockout mice with behavioral manifestations: where to look and what to search for., A V. Anagnostopoulos, J J. Sharp, L E. Mobraaten, J T. Eppig, and M T. Davisson

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Genetic modification of glaucoma associated phenotypes between AKXD-28/Ty and DBA/2J mice., M G. Anderson, R S. Smith, O V. Savinova, N L. Hawes, B Chang, A Zabaleta, R Wilpan, J R. Heckenlively, M Davisson, and S W. John

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Functional annotation of a full-length mouse cDNA collection., M Ashburner, C Gissi, B King, G Pesole, J Quackenbush, T Washio, C Bult, D Hill, M Ringwald, C Whittaker, and al et

T-cell contributions to alveolar bone loss in response to oral infection with Porphyromonas gingivalis., P J. Baker, J Garneau, L Howe, and D C. Roopenian

Variables to predict engraftment of umbilical cord blood into immunodeficient mice: usefulness of the non-obese diabetic--severe combined immunodeficient assay., K K. Ballen, H Valinski, D Greiner, L D. Shultz, P S. Becker, C C. Hsieh, F M. Stewart, and P J. Quesenberry

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Ducky mouse phenotype of epilepsy and ataxia is associated with mutations in the Cacna2d2 gene and decreased calcium channel current in cerebellar Purkinje cells., J Barclay, N Balaguero, M Mione, S L. Ackerman, V A. Letts, J Brodbeck, C Canti, A Meir, K M. Page, K Kusumi, Reyes E. Perez, E S. Lander, W N. Frankel, R M. Gardiner, A C. Dolphin, and M Rees

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Elizabeth S. Russell 1913-2001., J E. Barker

Quantitative trait loci for femoral and lumbar vertebral bone mineral density in C57BL/6J and C3H/HeJ inbred strains of mice., W G. Beamer, K L. Shultz, L R. Donahue, G A. Churchill, S Sen, J R. Wergedal, D J. Baylink, and C J. Rosen

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Abnormal dispersion of a purkinje cell subset in the mouse mutant cerebellar deficient folia (cdf)., E Beierbach, C Park, S L. Ackerman, D Goldowitz, and R Hawkes

The skeletal structure of insulin-like growth factor I-deficient mice., D Bikle, S Majumdar, A Laib, Braxton L. Powell, C Rosen, W Beamer, E Nauman, C Leary, and B Halloran

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Creating the gene ontology resource: design and implementation., J A. Blake, J Corradi, J T. Eppig, D P. Hill, J E. Richardson, M Ringwald, and al et

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The Mouse Genome Database (MGD): integration nexus for the laboratory mouse., J A. Blake, J T. Eppig, J E. Richardson, C J. Bult, and J A. Kadin

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International Workshop on Lessons From Animal Models for Human Type 1 Diabetes: identification of insulin but not glutamic acid decarboxylase or IA-2 as specific autoantigens of humoral autoimmunity in nonobese diabetic mice., E Bonifacio, M Atkinson, G Eisenbarth, D Serreze, T W. Kay, Chan E. Lee, and B Singh

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Packaging paternal chromosomes with protamine., R E. Braun

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Effects of dietary restriction on appendicular bone in the SENCAR mouse., Murray E. Brochmann, W G. Beamer, M E. Duarte, K Behnam, M S. Grisanti, and S S. Murray

How to study pathologic phenotypes of knockout mice., R T. Bronson

Mutations of the mouse Twist and sy (fibrillin 2) genes induced by chemical mutagenesis of ES cells., V L. Browning, S S. Chaudhry, A Planchart, M J. Dixon, and J C. Schimenti

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The mouse Hoxd13(spdh) mutation, a polyalanine expansion similar to human type II synpolydactyly (SPD), disrupts the function but not the expression of other Hoxd genes., S Bruneau, Kenneth R. Johnson, M Yamamoto, A Kuroiwa, and D Duboule

High-resolution genetic and physical mapping of modifier-of-deafwaddler (mdfw) and Waltzer (Cdh23v)., E C. Bryda, H J. Kim, M E. Legare, W N. Frankel, and Trauth K. Noben

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Web-based access to mouse models of human cancers: the Mouse Tumor Biology (MTB) Database., C J. Bult, D M. Krupke, D Naf, J P. Sundberg, and J T. Eppig

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Atherosclerosis in apoE knockout mice infected with multiple pathogens., M S. Burnett, C A. Gaydos, G E. Madico, S M. Glad, B Paigen, T C. Quinn, and S E. Epstein

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The mouse snail gene encodes a key regulator of the epithelial-mesenchymal transition., E A. Carver, R Jiang, Y Lan, K F. Oram, and T Gridley

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Haploinsufficient Bmp4 ocular phenotypes include anterior segment dysgenesis with elevated intraocular pressure., B Chang, R S. Smith, M Peters, O V. Savinova, N L. Hawes, A Zabaleta, S Nusinowitz, J E. Martin, M L. Davisson, C L. Cepko, B L. Hogan, and S W. John

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PPAR-gamma dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation., A Chawla, Y Barak, L Nagy, D Liao, P Tontonoz, and R M. Evans

A PPAR gamma-LXR-ABCA1 pathway in macrophages is involved in cholesterol efflux and atherogenesis., A Chawla, W A. Boisvert, C H. Lee, B A. Laffitte, Y Barak, S B. Joseph, D Liao, L Nagy, P A. Edwards, L K. Curtiss, R M. Evans, and P Tontonoz

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Characterization of the murine lbx2 promoter, identification of the human homologue, and evaluation as a candidate for alstrom syndrome., F Chen, G B. Collin, K C. Liu, D R. Beier, M Eccles, P M. Nishina, T Moshang, and J A. Epstein

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Mice deficient in methylenetetrahydrofolate reductase exhibit hyperhomocysteinemia and decreased methylation capacity, with neuropathology and aortic lipid deposition., Z Chen, A C. Karaplis, S L. Ackerman, I P. Pogribny, S Melnyk, Cacan S. Lussier, M F. Chen, A Pai, S W. John, R S. Smith, T Bottiglieri, P Bagley, J Selhub, M A. Rudnicki, S J. James, and R Rozen

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In silico mapping of mouse quantitative trait loci., E J. Chesler, Zas S. Rodriguez, and J S. Mogil

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Development and function of diabetogenic T-cells in B-cell-deficient nonobese diabetic mice., P P. Chiu, D V. Serreze, and J S. Danska

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Sex, flies and microarrays., G A. Churchill and B Oliver

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Reciprocal mouse and human limb phenotypes caused by gain- and loss-of-function mutations affecting lmbr1., R M. Clark, P C. Marker, E Roessler, A Dutra, J C. Schimenti, M Muenke, and D M. Kingsley

Mouse paracentric inversion In(3)55Rk mutates the urate oxidase gene., S A. Cook, E C. Akeson, C Calvano, K R. Johnson, J Mandell, N L. Hawes, R T. Bronson, T H. Roderick, and M T. Davisson

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PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oligoastrocytomas from neural progenitors and astrocytes in vivo., C Dai, J C. Celestino, Y Okada, D N. Louis, G N. Fuller, and E C. Holland

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Glioma models., C Dai and E C. Holland

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Evolutionary breakpoints on human chromosome 21., M T. Davisson, L J. Bechtel, E C. Akeson, A Fortna, D Slavov, and K Gardiner

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Transcriptional activity of the mouse oocyte genome: companion granulosa cells modulate transcription and chromatin remodeling., La Fuente De and J J. Eppig

Observed incidence of tumorigenesis in long-term rodent studies of rAAV vectors., A Donsante, C Vogler, N Muzyczka, J M. Crawford, J Barker, T Flotte, Thompson M. Campbell, T Daly, and M S. Sands

Fas deficiency delays the resolution of airway hyperresponsiveness after allergen sensitization and challenge., C Duez, A Tomkinson, L D. Shultz, D L. Bratton, and E W. Gelfand

Does one gene determine whether a C57BL/6J-Y(POS) mouse will develop as a female or as an hermaphrodite?, E M. Eicher and L L. Washburn

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Oocyte control of ovarian follicular development and function in mammals., J J. Eppig

Comparative mapping: tracking gene homologues among mammals., J T. Eppig

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Genetic analysis of case/control data using estimated haplotype frequencies: application to APOE locus variation and Alzheimer's disease., D Fallin, A Cohen, L Essioux, I Chumakov, M Blumenfeld, D Cohen, and N J. Schork

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A major quantitative trait locus on chromosome 3 controls colitis severity in IL-10-deficient mice., M A. Farmer, J P. Sundberg, I J. Bristol, G A. Churchill, R Li, C O. Elson, and E H. Leiter

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Mouse strain differences determine severity of iron accumulation in Hfe knockout model of hereditary hemochromatosis., R E. Fleming, C C. Holden, S Tomatsu, A Waheed, E M. Brunt, R S. Britton, B R. Bacon, D C. Roopenian, and W S. Sly

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Lifespan extension and delayed immune and collagen aging in mutant mice with defects in growth hormone production., K Flurkey, J Papaconstantinou, R A. Miller, and D E. Harrison

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Electroconvulsive thresholds of inbred mouse strains., W N. Frankel, L Taylor, B Beyer, B L. Tempel, and H S. White

Treatment of alopecia areata in C3H/HeJ mice with the topical immunosuppressant FK506 (Tacrolimus)., Paul P. Freyschmidt, A Ziegler, K J. McElwee, R Happle, S Kissling, J P. Sundberg, and R Hoffmann

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Deletion of the p27Kip1 gene restores normal development in cyclin D1-deficient mice., Y Geng, Q Yu, E Sicinska, M Das, R T. Bronson, and P Sicinski

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MSY2 and MSY4 bind a conserved sequence in the 3' untranslated region of protamine 1 mRNA in vitro and in vivo., F Giorgini, H G. Davies, and R E. Braun

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Previously undetected human hematopoietic cell populations with short-term repopulating activity selectively engraft NOD/SCID-beta2 microglobulin-null mice., H Glimm, W Eisterer, K Lee, J Cashman, T L. Holyoake, F Nicolini, L D. Shultz, Kalle C. von, and C J. Eaves

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Structure, chromosomal localization, and expression of the gene for mouse ecto-mono(ADP-ribosyl)transferase ART5., G Glowacki, R Braren, Cvrlje M. Cetkovic, E H. Leiter, F Haag, and Nolte F. Koch

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Diverse repertoire of the MHC class II-peptide complexes is required for presentation of viral superantigens., T Golovkina, Y Agafonova, D Kazansky, and A Chervonsky

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DelBank: a mouse ES-cell resource for generating deletions., N C. Goodwin, Y Ishida, S Hartford, C Wnek, R A. Bergstrom, P Leder, and J C. Schimenti

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Rat xenograft survival in mice treated with donor-specific transfusion and anti-CD154 antibody is enhanced by elimination of host CD4+ cells., E J. Gordon, B A. Woda, L D. Shultz, A A. Rossini, D L. Greiner, and J P. Mordes

Pemphigus: an unfolding story., S A. Grando, M R. Pittelkow, L D. Shultz, M Dmochowski, and V T. Nguyen

Notch signaling during vascular development., T Gridley

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Brown adipose tissue-specific insulin receptor knockout shows diabetic phenotype without insulin resistance., C Guerra, P Navarro, A M. Valverde, M Arribas, J Bruning, L P. Kozak, C R. Kahn, and M Benito

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Establishing an ENU mutagenesis screen for the piebald region of mouse Chromosome 14., Greenberg A. Hagge, P Snow, and T P. O'Brien

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Excess cone cell proliferation due to lack of a functional NR2E3 causes retinal dysplasia and degeneration in rd7/rd7 mice., N B. Haider, J K. Naggert, and P M. Nishina

Of mice and genome sequence., B A. Hamilton and W N. Frankel

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Transgenic rescue implicates beta 2-microglobulin as a diabetes susceptibility gene in nonobese diabetic (NOD) mice., Williams E. Hamilton, D V. Serreze, B Charlton, E A. Johnson, M P. Marron, A Mullbacher, and R M. Slattery

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Controlling exposure to laboratory animal allergens., D J. Harrison

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Program description: Strategies for biological annotation of mammalian systems: implementing gene ontologies in mouse genome informatics., D P. Hill, A P. Davis, J E. Richardson, J P. Corradi, M Ringwald, J T. Eppig, and J A. Blake

Cytomegalovirus infection increases development of atherosclerosis in Apolipoprotein-E knockout mice., E Hsich, Y F. Zhou, B Paigen, T M. Johnson, M S. Burnett, and S E. Epstein

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Mutation of the hematopoietic cell phosphatase (Hcph) gene is associated with resistance to gamma-irradiation-induced apoptosis in Src homology protein tyrosine phosphatase (SHP)-1-deficient "motheaten" mutant mice., H C. Hsu, L D. Shultz, X Su, J Shi, P A. Yang, M J. Relyea, H G. Zhang, and J D. Mountz

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Cutting edge: systemic inhibition of angiogenesis underlies resistance to tumors during acute toxoplasmosis., C A. Hunter, D Yu, M Gee, C V. Ngo, C Sevignani, M Goldschmidt, T V. Golovkina, S Evans, W F. Lee, and Tikhonenko A. Thomas

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Expression of genes involved in mammalian meiosis during the transition from egg to embryo., S Y. Hwang, B Oh, B B. Knowles, D Solter, and J S. Lee

Effects of ectopias and their cortical location on several measures of learning in BXSB mice., L A. Hyde, B J. Hoplight, S Harding, G F. Sherman, L E. Mobraaten, and V H. Denenberg

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Neural tube defects and neuroepithelial cell death in Tulp3 knockout mice., A Ikeda, S Ikeda, T Gridley, P M. Nishina, and J K. Naggert

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Primary hyperparathyroidism caused by parathyroid-targeted overexpression of cyclin D1 in transgenic mice., Y Imanishi, Y Hosokawa, K Yoshimoto, E Schipani, S Mallya, A Papanikolaou, O Kifor, T Tokura, M Sablosky, F Ledgard, G Gronowicz, T C. Wang, E V. Schmidt, C Hall, E M. Brown, R Bronson, and A Arnold

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Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras., E L. Jackson, N Willis, K Mercer, R T. Bronson, D Crowley, R Montoya, T Jacks, and D A. Tuveson

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Inhibition of autoimmune diabetes in nonobese diabetic mice by transgenic restoration of h2-e mhc class ii expression: additive, but unequal, involvement of multiple apc subtypes., E A. Johnson, P Silveira, H D. Chapman, E H. Leiter, and D V. Serreze

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A nuclear-mitochondrial DNA interaction affecting hearing impairment in mice., K R. Johnson, Q Y. Zheng, Y Bykhovskaya, O Spirina, and Ghodsian N. Fischel

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Somatic activation of the K-ras oncogene causes early onset lung cancer in mice., L Johnson, K Mercer, D Greenbaum, R T. Bronson, D Crowley, D A. Tuveson, and T Jacks

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The molecular bases of spontaneous immunological mutations in the mouse and their homologous human diseases., M J Joliat and Leonard D. Shultz

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Regulation of prostaglandin-endoperoxide synthase 2 messenger ribonucleic acid expression in mouse granulosa cells during ovulation., I M. Joyce, F L. Pendola, M O'Brien, and J J. Eppig

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Biochemical and biophysical evidence for gamma 2 subunit association with neuronal voltage-activated Ca2+ channels., M G. Kang, C C. Chen, R Felix, V A. Letts, W N. Frankel, Y Mori, and K P. Campbell

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Bootstrapping cluster analysis: assessing the reliability of conclusions from microarray experiments., M K. Kerr and G A. Churchill