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Submissions from 2003

Molecular oncodiagnostics: where we are and where we need to go., Edison T. Liu

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Cutaneous smooth muscle tumors in the dog and cat., S M. Liu and I Mikaelian

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PERK eIF2alpha kinase regulates neonatal growth by controlling the expression of circulating insulin-like growth factor-I derived from the liver., Y Li, K Iida, J O'Neil, P Zhang, S Li, A Frank, A Gabai, F Zambito, S H. Liang, C J. Rosen, and D R. Cavener

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A single nucleotide polymorphism in the Emp3 gene defines the H4 minor histocompatibility antigen., B Luedtke, L M. Pooler, E Y. Choi, A M. Tranchita, C J. Reinbold, A C. Brown, D J. Shaffer, D C. Roopenian, and S Malarkannan

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Mechanisms of anemia in SHP-1 protein tyrosine phosphatase-deficient "viable motheaten" mice., B L. Lyons, M A. Lynes, L Burzenski, M J. Joliat, N Hadjout, and L D. Shultz

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Quantitative trait loci that determine lipoprotein cholesterol levels in DBA/2J and CAST/Ei inbred mice., M A. Lyons, H Wittenburg, R Li, K A. Walsh, G A. Churchill, M C. Carey, and B Paigen

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New quantitative trait loci that contribute to cholesterol gallstone formation detected in an intercross of CAST/Ei and 129S1/SvImJ inbred mice., M A. Lyons, H Wittenburg, R Li, K A. Walsh, M R. Leonard, G A. Churchill, M C. Carey, and B Paigen

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Lith6: a new QTL for cholesterol gallstones from an intercross of CAST/Ei and DBA/2J inbred mouse strains., M A. Lyons, H Wittenburg, R Li, K A. Walsh, M R. Leonard, R Korstanje, G A. Churchill, M C. Carey, and B Paigen

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Conditional mutation of Rb causes cell cycle defects without apoptosis in the central nervous system., D MacPherson, J Sage, D Crowley, A Trumpp, R T. Bronson, and T Jacks

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'Cyclic alopecia' in Msx2 mutants: defects in hair cycling and hair shaft differentiation., L Ma, J Liu, T Wu, M Plikus, T X. Jiang, Q Bi, Y H. Liu, Rover S. Muller, H Peters, J P. Sundberg, R Maxson, R L. Maas, and C M. Chuong

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Genetic analysis of resistance to Type-1 Diabetes in ALR/Lt mice, a NOD-related strain with defenses against autoimmune-mediated diabetogenic stress., C E. Mathews, R T. Graser, R J. Bagley, J W. Caldwell, R Li, G A. Churchill, D V. Serreze, and E H. Leiter

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The pathogenesis of alopecia areata in rodent models., K J. McElwee, Paul P. Freyschmidt, J P. Sundberg, and R Hoffmann

Dietary soy oil content and soy-derived phytoestrogen genistein increase resistance to alopecia areata onset in C3H/HeJ mice., K J. McElwee, S Niiyama, Paul P. Freyschmidt, E Wenzel, S Kissling, J P. Sundberg, and R Hoffmann

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Alopecia areata in C3H/HeJ mice involves leukocyte-mediated root sheath disruption in advance of overt hair loss., K J. McElwee, K Silva, D Boggess, L Bechtold, L E. King, and J P. Sundberg

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CRB1 is essential for external limiting membrane integrity and photoreceptor morphogenesis in the mammalian retina., A K. Mehalow, S Kameya, R S. Smith, N L. Hawes, J M. Denegre, J A. Young, L Bechtold, N B. Haider, U Tepass, J R. Heckenlively, B Chang, J K. Naggert, and P M. Nishina

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Adenomatous hyperplasia of the thyroid gland in beluga whales (Delphinapterus leucas) from the St. Lawrence Estuary and Hudson Bay, Quebec, Canada., I Mikaelian, P Labelle, M Kopal, Guise S. De, and D Martineau

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Follicular stem cell carcinoma: histologic, immunohistochemical, ultrastructural, and clinical characterization in 30 dogs., I Mikaelian and V Wong

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Effect of heterozygous PPARgamma deficiency and TZD treatment on insulin resistance associated with age and high-fat feeding., P D. Miles, Y Barak, R M. Evans, and J M. Olefsky

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Fluorescence imaging of multiple myeloma cells in a clinically relevant SCID/NOD in vivo model: biologic and clinical implications., C S. Mitsiades, N S. Mitsiades, R T. Bronson, D Chauhan, N Munshi, S P. Treon, C A. Maxwell, L Pilarski, T Hideshima, R M. Hoffman, and K C. Anderson

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The melanocortin-1 receptor gene mediates female-specific mechanisms of analgesia in mice and humans., J S. Mogil, S G. Wilson, E J. Chesler, A L. Rankin, K V. Nemmani, W R. Lariviere, M K. Groce, M R. Wallace, and al et

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Insulin-like growth factor regulates peak bone mineral density in mice by both growth hormone-dependent and -independent mechanisms., S Mohan, C Richman, R Guo, Y Amaar, L R. Donahue, J Wergedal, and D J. Baylink

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By Altering Ocular Immune Privilege, Bone Marrow-derived Cells Pathogenically Contribute to DBA/2J Pigmentary Glaucoma., J S. Mo, M G. Anderson, M Gregory, R S. Smith, O V. Savinova, D V. Serreze, B R. Ksander, J W. Streilein, and S W. John

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Evidence that the red cell skeleton protein 4.2 interacts with the Rh membrane complex member CD47., Chanteloup I. Mouro, J Delaunay, P Gane, V Nicolas, M Johansen, E J. Brown, L L. Peters, Kim C. Van, J P. Cartron, and Y Colin

Assessing the risk of transmission of three infectious agents among mice housed in a negatively pressurized caging system., D D. Myers, E Smith, I Schweitzer, J D. Stockwell, B J. Paigen, R Bates, J Palmer, and A L. Smith

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Pleiotropy, homeostasis, and functional networks based on assays of cardiovascular traits in genetically randomized populations., J H. Nadeau, L C. Burrage, J Restivo, Y H. Pao, G Churchill, and B D. Hoit

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Essential role for the peroxiredoxin Prdx1 in erythrocyte antioxidant defence and tumour suppression., C A. Neumann, D S. Krause, C V. Carman, S Das, D P. Dubey, J L. Abraham, R T. Bronson, Y Fujiwara, S H. Orkin, and Etten R. Van

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Rh-RhAG/ankyrin-R, a new interaction site between the membrane bilayer and the red cell skeleton, is impaired by Rh(null)-associated mutation., V Nicolas, V a. Le, P Gane, C Birkenmeier, J P. Cartron, Y Colin, and Chanteloup I. Mouro

Mouse genetic approaches to access pathways important in retinal function., P M. Nishina and J K. Naggert

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Association of cadherin 23 with polygenic inheritance and genetic modification of sensorineural hearing loss., Trauth K. Noben, Q Y. Zheng, and K R. Johnson

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Hepatic lipase expression in macrophages contributes to atherosclerosis in apoE-deficient and LCAT-transgenic mice., Z Nong, Navarro H. Gonzalez, M Amar, L Freeman, C Knapper, E B. Neufeld, B J. Paigen, R F. Hoyt, Najib J. Fruchart, and Fojo S. Santamarina

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A revised protocol for in vitro development of mouse oocytes from primordial follicles dramatically improves their developmental competence., M J. O'Brien, J K. Pendola, and J J. Eppig

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Genome function and nuclear architecture: from gene expression to nanoscience., T P. O'Brien, C J. Bult, C Cremer, M Grunze, B B. Knowles, J Langowski, J McNally, T Pederson, J C. Politz, A Pombo, G Schmahl, J P. Spatz, and Driel R. van

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Our small relative., T O'Brien and R Woychik

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Slug expression during organogenesis in mice., K F. Oram, E A. Carver, and T Gridley

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Progress toward understanding the genetic and biochemical mechanisms of inherited photoreceptor degenerations., L R. Pacione, M J. Szego, S Ikeda, P M. Nishina, and R R. McInnes

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Primed Peritoneal B Lymphocytes Are Sufficient To Transfer Protection against Brugia pahangi Infection in Mice., N Paciorkowski, L D. Shultz, and T V. Rajan

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One Hundred Years of Mouse Genetics. An intellectual history. ii. the molecular revolution (1981-2002)., K Paigen

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One Hundred Years of Mouse Genetics. An intellectual history. i. the classical period (1902-1980)., K Paigen

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Cell-specific mitotic defect and dyserythropoiesis associated with erythroid band 3 deficiency., B H. Paw, A J. Davidson, Y Zhou, R Li, C Lee, A Donovan, A H. Drejer, B Gwynn, L L. Peters, M N. Chernova, S N. Wickramasinghe, M J. Lee, S E. Lux, and al et

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Genetic disassociation of autoimmunity and resistance to costimulation blockade-induced transplantation tolerance in nonobese diabetic mice., T Pearson, T G. Markees, D V. Serreze, M A. Pierce, M P. Marron, L S. Wicker, L B. Peterson, L D. Shultz, J P. Mordes, A A. Rossini, and D L. Greiner

Genetic separation of the transplantation tolerance and autoimmune phenotypes in NOD mice., T Pearson, T G. Markees, D V. Serreze, M A. Pierce, L S. Wicker, L B. Peterson, L D. Shultz, J P. Mordes, A A. Rossini, and D L. Greiner

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Islet cell autoimmunity and transplantation tolerance: two distinct mechanisms?, T Pearson, T G. Markees, D V. Serreze, M A. Pierce, L S. Wicker, L B. Peterson, L D. Shultz, J P. Mordes, A A. Rossini, and D L. Greiner

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NOD congenic mice genetically protected from autoimmune diabetes remain resistant to transplantation tolerance induction., T Pearson, T G. Markees, L S. Wicker, D V. Serreze, L B. Peterson, J P. Mordes, A A. Rossini, and D L. Greiner

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Genetic models in applied physiology: selected contribution: effects of spaceflight on immunity in the C57BL/6 mouse. I. Immune population distributions., M J. Pecaut, G A. Nelson, L L. Peters, P J. Kostenuik, T A. Bateman, S Morony, L S. Stodieck, D L. Lacey, S J. Simske, and D S. Gridley

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Genetic architecture of the mouse hippocampus: identification of gene loci with selective regional effects., J L. Peirce, E J. Chesler, R W. Williams, and L Lu

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On the normalization of RNA equilibrium free energy to the length of the sequence., D D. Pervouchine, J H. Graber, and S Kasif

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Overexpression of Prdx6 reduces H2O2 but does not prevent diet-induced atherosclerosis in the aortic root., S A. Phelan, X Wang, P Wallbrandt, Semb K. Forsman, and B Paigen

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Adenovirus Early Region 3 Antiapoptotic 10.4K, 14.5K, and 14.7K Genes Decrease the Incidence of Autoimmune Diabetes in NOD Mice., M A. Pierce, H D. Chapman, C M. Post, A Svetlanov, S Efrat, M Horwitz, and D V. Serreze

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Unique resistance of I/LnJ mice to a retrovirus is due to sustained interferon gamma-dependent production of virus-neutralizing antibodies., A Purdy, L Case, M Duvall, Coleman M. Overstrom, N Monnier, A Chervonsky, and T Golovkina

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Meiosis in male PL/J mice: a genetic model for gametic aneuploidy., A Pyle and M A. Handel

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Animal and in vitro models for the study of hair follicles., V A. Randall, J P. Sundberg, and M P. Philpott

An essential role of Th1 responses and interferon gamma in infection-mediated suppression of neoplastic growth., E B. Rankin, D Yu, J Jiang, H Shen, E J. Pearce, M H. Goldschmidt, D E. Levy, T V. Golovkina, C A. Hunter, and Tikhonenko A. Thomas

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Adoptive transfer of islet antigen-autoreactive T cell clones to transgenic NOD.Ea(d)mice induces diabetes indicating a lack of I-E mediated protection against activated effector T cells., S A. Roberts, G Barbour, M R. Matarrese, D L. Mason, E H. Leiter, K Haskins, and M S. Hanson

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Evidence for a skeletal mechanosensitivity gene on mouse chromosome 4., A G. Robling, J Li, K L. Shultz, W G. Beamer, and C H. Turner

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The MHC Class I-Like IgG Receptor Controls Perinatal IgG Transport, IgG Homeostasis, and Fate of IgG-Fc-Coupled Drugs., D C. Roopenian, G J. Christianson, T J. Sproule, A C. Brown, S Akilesh, N Jung, S Petkova, L Avanessian, E Y. Choi, D J. Shaffer, P A. Eden, and C L. Anderson

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Insulin-like growth factor I and calcium balance: evolving concepts of an evolutionary process., C J. Rosen

Restoring aging bones., C J. Rosen

The cellular and clinical parameters of anabolic therapy for osteoporosis., C J. Rosen

Severe hypocalcemia after intravenous bisphosphonate therapy in occult vitamin D deficiency., C J. Rosen and S Brown

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Growth hormone rising: did we quit too quickly?, C J. Rosen and C Wuster

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The comprehensive mouse radiation hybrid map densely cross-referenced to the recombination map: a tool to support the sequence assemblies., L B. Rowe, M E. Barter, J A. Kelmenson, and J T. Eppig

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A goodbye to Charlie Janeway: Charles A. Janeway Jr (1943-2003)., A S. Rudensky and A S. Chervonsky

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Skeletal unloading induces resistance to insulin-like growth factor I on bone formation., T Sakata, B P. Halloran, H Z. Elalieh, S J. Munson, L Rudner, L Venton, D Ginzinger, C J. Rosen, and D D. Bikle

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The SCAN domain defines a large family of zinc finger transcription factors., T L. Sander, K F. Stringer, J L. Maki, P Szauter, J R. Stone, and T Collins

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Contribution of Fas to diabetes development., A Y. Savinov, A Tcherepanov, E A. Green, R A. Flavell, and A V. Chervonsky

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Presentation of Antigen by Endothelial Cells and Chemoattraction Are Required for Homing of Insulin-specific CD8(+) T Cells., A Y. Savinov, F S. Wong, A C. Stonebraker, and A V. Chervonsky

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Presentation of antigen by endothelial cells and chemoattraction are required for homing of insulin-specific CD8+ T cells., A Y. Savinov, F S. Wong, A C. Stonebraker, and A V. Chervonsky

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Human disease genes and their cloned mouse orthologs: exploration of the FANTOM2 cDNA sequence data set., L M. Schriml, D P. Hill, J A. Blake, H Bono, Boris A. Wynshaw, W J. Pavan, B Z. Ring, K Beisel, M Setou, and Y Okazaki

Cutaneous fibropapilloma in a mountain lion (Felis concolor)., F Y. Schulman, A E. Krafft, T Janczewski, I Mikaelian, J Irwin, and K Hassinger

Reducing exposure to laboratory animal allergens., I B. Schweitzer, E Smith, D J. Harrison, D D. Myers, P A. Eggleston, J D. Stockwell, B Paigen, and A L. Smith

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Tracking autoimmune T cells in diabetes., D V. Serreze and E H. Leiter

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Paralytic Autoimmune Myositis Develops in Nonobese Diabetic Mice Made Th1 Cytokine-Deficient by Expression of an IFN-gamma Receptor beta-Chain Transgene., D V. Serreze, M A. Pierce, C M. Post, H D. Chapman, H Savage, R T. Bronson, P B. Rothman, and G A. Cox

The role of B lymphocytes as key antigen-presenting cells in the development of T cell-mediated autoimmune type 1 diabetes., D V. Serreze and P A. Silveira

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Phenotype-based identification of mouse chromosome instability mutants., N Shima, S A. Hartford, T Duffy, L A. Wilson, K J. Schimenti, and J C. Schimenti

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Clustering of multiple specific genes and gene-rich R-bands around SC-35 domains: evidence for local euchromatic neighborhoods., L S. Shopland, C V. Johnson, M Byron, J McNeil, and J B. Lawrence

Congenic strains of mice for verification and genetic decomposition of quantitative trait loci for femoral bone mineral density., K L. Shultz, L R. Donahue, M L. Bouxsein, D J. Baylink, C J. Rosen, and W G. Beamer

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Regulation of human short-term repopulating cell (STRC) engraftment in NOD/SCID mice by host CD122+ cells., L D. Shultz, S J. Banuelos, J Leif, M C. Appel, M Cunningham, K Ballen, L Burzenski, and D L. Greiner

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NOD/LtSz-Rag1nullPfpnull mice: a new model system with increased levels of human peripheral leukocyte and hematopoietic stem-cell engraftment., L D. Shultz, S Banuelos, B Lyons, R Samuels, L Burzenski, B Gott, P Lang, J Leif, M Appel, A Rossini, and D L. Greiner

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Mutations at the mouse ichthyosis locus are within the lamin B receptor gene: a single gene model for human Pelger-Huet anomaly., L D. Shultz, B L. Lyons, L M. Burzenski, B Gott, R Samuels, P A. Schweitzer, C Dreger, H Herrmann, V Kalscheuer, A L. Olins, D E. Olins, K Sperling, and K Hoffmann

Perturbations in bone formation and resorption in insulin-like growth factor binding protein-3 transgenic mice., J V. Silha, S Mishra, C J. Rosen, W G. Beamer, R T. Turner, D R. Powell, and L J. Murphy

Factors related to the use of bone densitometry: survey responses of 494 primary care physicians in New England., D H. Solomon, M T. Connelly, C J. Rosen, Hughes B. Dawson, D P. Kiel, S L. Greenspan, E S. Leib, M Holick, A H. Miguel, and J S. Finkelstein

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New paths to human ES cells?, D Solter

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Successful allogeneic neonatal bone marrow transplantation devoid of myeloablation requires costimulatory blockade., B W. Soper, M D. Lessard, C D. Jude, A J. Schuldt, R M. Bunte, and J E. Barker

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T cells are required for host protection against Brugia malayi but need not produce or respond to interleukin-4., L Spencer, L Shultz, and T V. Rajan

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Another view of T cell antigen recognition: cooperative engagement of glycolipid antigens by Va14Ja18 natural TCR., A K. Stanic, R Shashidharamurthy, J S. Bezbradica, N Matsuki, Y Yoshimura, S Miyake, E Y. Choi, T D. Schell, K a. Van, S S. Tevethia, D C. Roopenian, T Yamamura, and S Joyce

Antioxidant protein 2 prevents methemoglobin formation in erythrocyte hemolysates., K M. Stuhlmeier, J J. Kao, P Wallbrandt, M Lindberg, B Hammarstrom, H Broell, and B Paigen

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Necropsy procedures with histopathologic evaluation of tissues are fundamentally the same regardless of species., J P. Sundberg

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Major Locus on Mouse Chromosome 17 and Minor Locus on Chromosome 9 are Linked with Alopecia Areata in C3H/HeJ Mice., J P. Sundberg, D Boggess, K A. Silva, K J. McElwee, L E. King, R Li, G Churchill, and G A. Cox

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Mouse alopecia areata models: an array of data on mechanisms and genetics., J P. Sundberg and L E. King

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Oocyte-dependent activation of mitogen-activated protein kinase (ERK1/2) in cumulus cells is required for the maturation of the mouse oocyte-cumulus cell complex., Y Q. Su, J M. Denegre, K Wigglesworth, F L. Pendola, M J. O'Brien, and J J. Eppig

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Genetic Models in Applied Physiology: Invited Review: Identifying new mouse models of cardiovascular disease: a review of high-throughput screens of mutagenized and inbred strains., K L. Svenson, M A. Bogue, and L L. Peters

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Rb and N-ras function together to control differentiation in the mouse., C Takahashi, R T. Bronson, M Socolovsky, B Contreras, K Y. Lee, T Jacks, M Noda, R Kucherlapati, and M E. Ewen

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Topical mechlorethamine restores autoimmune-arrested follicular activity in mice with an alopecia areata-like disease by targeting infiltrated lymphocytes., L Tang, L Cao, O Bernardo, Y Chen, J P. Sundberg, H Lui, S Chung, and J Shapiro

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Restoration of hair growth with topical diphencyprone in mouse and rat models of alopecia areata., L Tang, H Lui, J P. Sundberg, R Bissonnette, D I. McLean, and J Shapiro

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Old wine in new bottles: reviving old therapies for alopecia areata using rodent models., L Tang, J P. Sundberg, H Lui, and J Shapiro

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Expansion of hematopoietic stem cell phenotype and activity in Trp53-null mice., M TeKippe, D E. Harrison, and J Chen

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Alloimmune injury and rejection of human skin grafts on human peripheral blood lymphocyte-reconstituted non-obese diabetic severe combined immunodeficient beta2-microglobulin-null mice., N A. Turgeon, S J. Banuelos, L D. Shultz, B L. Lyons, N Iwakoshi, D L. Greiner, J P. Mordes, A A. Rossini, and M C. Appel

Congenic mice reveal sex-specific genetic regulation of femoral structure and strength., C H. Turner, Q Sun, J Schriefer, N Pitner, R Price, M L. Bouxsein, C J. Rosen, L R. Donahue, K L. Shultz, and W G. Beamer

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Characterization of protein kinase C-delta in mouse oocytes throughout meiotic maturation and following egg activation., M M. Viveiros, M O'Brien, K Wigglesworth, and J J. Eppig

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Mutations in the murine erythroid alpha -spectrin gene alter spectrin mRNA and protein levels and spectrin incorporation into the red blood cell membrane skeleton., N J. Wandersee, C S. Birkenmeier, D M. Bodine, N Mohandas, and J E. Barker