Submissions from 2004
Evidence for a conserved function in synapse formation reveals Phr1 as a candidate gene for respiratory failure in newborn mice., R W. Burgess, K A. Peterson, M J. Johnson, J J. Roix, I C. Welsh, and T P. O'Brien
Hybrid poplar and forest soil response to municipal and industrial by-products: a greenhouse study., M A. Cavaleri, D W. Gilmore, M Mozaffari, C J. Rosen, and T R. Halbach
Cross-priming of CD8+ T cells by viral and tumor antigens is a robust phenomenon., W Chen, K A. Masterman, S Basta, S M. Haeryfar, N Dimopoulos, B Knowles, J R. Bennink, and J W. Yewdell
WebQTL: rapid exploratory analysis of gene expression and genetic networks for brain and behavior., E J. Chesler, L Lu, J Wang, R W. Williams, and K F. Manly
Brain gene expression: genomics and genetics., E J. Chesler and R W. Williams
Enhanced pathogenicity of diabetogenic T cells escaping a non-MHC gene-controlled near death experience., Rossi C. Choisy, T M. Holl, M A. Pierce, H D. Chapman, and D V. Serreze
The relative levels of translin-associated factor X (TRAX) and testis brain RNA-binding protein determine their nucleocytoplasmic distribution in male germ cells., Y S. Cho, V M. Chennathukuzhi, M A. Handel, J Eppig, and N B. Hecht
Using ANOVA to analyze microarray data., G A. Churchill
The Collaborative Cross, a community resource for the genetic analysis of complex traits., G A. Churchill, M Bogue, B Paigen, K Paigen, K Svenson, H U. Pan, E J. Chesler, and Trait Committee Complex
Implementing large-scale ENU mutagenesis screens in North America., A T. Clark, D Goldowitz, J S. Takahashi, M H. Vitaterna, S M. Siepka, L L. Peters, W N. Frankel, G A. Carlson, J Rossant, J H. Nadeau, and M J. Justice
Cholesterol synthesis inhibition distal to squalene upregulates biliary phospholipid secretion and counteracts cholelithiasis in the genetically prone C57L/J mouse., G A. Clarke, G Bouchard, B Paigen, and M C. Carey
Mutation rate and predicted phenotypic target sizes in ethylnitrosourea-treated mice., D Concepcion, K L. Seburn, G Wen, W N. Frankel, and B A. Hamilton
Major chromatin remodeling in the germinal vesicle (GV) of mammalian oocytes is dispensable for global transcriptional silencing but required for centromeric heterochromatin function., La Fuente De, M M. Viveiros, K H. Burns, E Y. Adashi, M M. Matzuk, and J J. Eppig
ATRX, a member of the SNF2 family of helicase/ATPases, is required for chromosome alignment and meiotic spindle organization in metaphase II stage mouse oocytes., La Fuente De, M M. Viveiros, K Wigglesworth, and J J. Eppig
Maternal beta-catenin and E-cadherin in mouse development., Vries W. De, A V. Evsikov, B E. Haac, K S. Fancher, A E. Holbrook, R Kemler, D Solter, and B B. Knowles
Genetic analysis of blood pressure in C3H/HeJ and SWR/J mice., K DiPetrillo, S W. Tsaih, S Sheehan, C Johns, P Kelmenson, H Gavras, G A. Churchill, and B Paigen
Notch3 is required for arterial identity and maturation of vascular smooth muscle cells., V Domenga, P Fardoux, P Lacombe, M Monet, J Maciazek, L T. Krebs, B Klonjkowski, E Berrou, M Mericskay, Z Li, Lasserve E. Tournier, T Gridley, and A Joutel
Hair cycle-specific immunolocalization of retinoic acid synthesizing enzymes Aldh1a2 and Aldh1a3 indicate complex regulation., H B. Everts, L E. King, J P. Sundberg, and D E. Ong
Systems biology of the 2-cell mouse embryo., A V. Evsikov, Vries W. de, A E. Peaston, E E. Radford, K S. Fancher, F H. Chen, J A. Blake, C J. Bult, K E. Latham, D Solter, and B B. Knowles
CTLA-4-Ig activates forkhead transcription factors and protects dendritic cells from oxidative stress in nonobese diabetic mice., F Fallarino, R Bianchi, C Orabona, C Vacca, M L. Belladonna, M C. Fioretti, D V. Serreze, U Grohmann, and P Puccetti
Nitric oxide regulates receptor activator of nuclear factor-kappaB ligand and osteoprotegerin expression in bone marrow stromal cells., X Fan, E Roy, L Zhu, T C. Murphy, Bicknell C. Ackert, C M. Hart, C Rosen, M S. Nanes, and J Rubin
Hepatic overexpression of murine Abcb11 increases hepatobiliary lipid secretion and reduces hepatic steatosis., A Figge, F Lammert, B Paigen, A Henkel, S Matern, R Korstanje, B L. Shneider, F Chen, E Stoltenberg, K Spatz, F Hoda, D E. Cohen, and R M. Green
Pitfalls of animal model systems in ageing research., K Flurkey and J M. Currer
Building protein interaction maps for Down's syndrome., K Gardiner, M T. Davisson, and L S. Crnic
Equine papillomavirus type 1: complete nucleotide sequence and characterization of recombinant virus-like particles composed of the EcPV-1 L1 major capsid protein., S J. Ghim, A Rector, H Delius, J P. Sundberg, A B. Jenson, and Ranst M. Van
Large-scale mutagenesis of the mouse to understand the genetic bases of nervous system structure and function., D Goldowitz, W N. Frankel, J S. Takahashi, Vitaterna M. Holtz, C Bult, W A. Kibbe, J Snoddy, Y Li, S Pretel, J Yates, and D J. Swanson
The ligand-binding function of hepatic lipase modulates the development of atherosclerosis in transgenic mice., Navarro H. Gonzalez, Z Nong, M J. Amar, R D. Shamburek, Fruchart J. Najib, B J. Paigen, H B. Brewer, and Fojo S. Santamarina
Phenotypic and molecular assessment of seven patients with 6p25 deletion syndrome: relevance to ocular dysgenesis and hearing impairment., D B. Gould, M S. Jaafar, M K. Addison, F Munier, R Ritch, I M. MacDonald, and M A. Walter
Genetically increasing Myoc expression supports a necessary pathologic role of abnormal proteins in glaucoma., D B. Gould, Libby L. Miceli, O V. Savinova, M Torrado, S I. Tomarev, R S. Smith, and S W. John
Anterior segment development relevant to glaucoma., D B. Gould, R S. Smith, and S W. John
Kick it up a Notch: NOTCH1 activation in T-ALL., T Gridley
A collaborative database of inbred mouse strain characteristics., S C. Grubb, G A. Churchill, and M A. Bogue
Reduced pigmentation (rp), a mouse model of Hermansky-Pudlak syndrome, encodes a novel component of the BLOC-1 complex., B Gwynn, J A. Martina, J S. Bonifacino, E V. Sviderskaya, M L. Lamoreux, D C. Bennett, K Moriyama, M Huizing, Wooley A. Helip, W A. Gahl, L S. Webb, A J. Lambert, and L L. Peters
A requirement for Notch1 distinguishes 2 phases of definitive hematopoiesis during development., B K. Hadland, S S. Huppert, J Kanungo, Y Xue, R Jiang, T Gridley, R A. Conlon, A M. Cheng, R Kopan, and G D. Longmore
Marking Xs, together and separately., M A. Handel
The XY body: a specialized meiotic chromatin domain., M A. Handel
The Gene Ontology (GO) database and informatics resource., M A. Harris, J Clark, M Ashburner, K Eilbeck, J Richter, G M. Rubin, J A. Blake, C Bult, M Dolan, H Drabkin, J T. Eppig, D P. Hill, M Ringwald, and R Balakrishnan
Quantitative gene expression profiling implicates genes for susceptibility and resistance to alveolar bone loss., G T. Hart, D J. Shaffer, S Akilesh, A C. Brown, L Moran, D C. Roopenian, and P J. Baker
Lipopolysaccharide-induced osteoclastogenesis in Src homology 2-domain phosphatase-1-deficient viable motheaten mice., S Hayashi, M Tsuneto, T Yamada, M Nose, M Yoshino, L D. Shultz, and H Yamazaki
Divide and die: cell cycle events as triggers of nerve cell death., K Herrup, R Neve, S L. Ackerman, and A Copani
Transcription profiling of inner ears from Pou4f3(ddl/ddl) identifies Gfi1 as a target of the Pou4f3 deafness gene., R Hertzano, M Montcouquiol, Elkeles S. Rashi, R Elkon, R Yucel, W N. Frankel, G Rechavi, T Moroy, T B. Friedman, M W. Kelley, and K B. Avraham
First cleavage plane of the mouse egg is not predetermined but defined by the topology of the two apposing pronuclei., T Hiiragi and D Solter
The mouse Gene Expression Database (GXD): updates and enhancements., D P. Hill, D A. Begley, J H. Finger, C M. Smith, L E. Corbani, J A. Blake, J T. Eppig, J A. Kadin, J E. Richardson, and M Ringwald
Androgen receptor function is required in Sertoli cells for the terminal differentiation of haploid spermatids., R W. Holdcraft and R E. Braun
Hormonal regulation of spermatogenesis., R W. Holdcraft and R E. Braun
Regulation of postsurgical fibrosis by the programmed death-1 inhibitory pathway., M A. Holsti, T Chitnis, R J. Panzo, R T. Bronson, H Yagita, M H. Sayegh, and A O. Tzianabos
Disruption of muscle membrane and phenotype divergence in two novel mouse models of dysferlin deficiency., M Ho, C M. Post, L R. Donahue, H G. Lidov, R T. Bronson, H Goolsby, S C. Watkins, G A. Cox, and R H. Brown
Identification of a cryptic lethal mutation in the mouse t(w73) haplotype., G R. Howell, R A. Bergstrom, R J. Munroe, J Masse, and J C. Schimenti
Requirement of Src kinases Lyn, Hck and Fgr for BCR-ABL1-induced B-lymphoblastic leukemia but not chronic myeloid leukemia., Y Hu, Y Liu, S Pelletier, E Buchdunger, M Warmuth, D Fabbro, M Hallek, Etten R. Van, and S Li
Age-related increases in calcium-binding protein immunoreactivity in the cochlear nucleus of hearing impaired C57BL/6J mice., E Idrizbegovic, N Bogdanovic, J F. Willott, and B Canlon
Mitogen-activated protein kinase dynamics during the meiotic G2/MI transition of mouse spermatocytes., A Inselman and M A. Handel
Human cord blood- and bone marrow-derived CD34+ cells regenerate gastrointestinal epithelial cells., F Ishikawa, M Yasukawa, S Yoshida, K Nakamura, Y Nagatoshi, T Kanemaru, K Shimoda, S Shimoda, T Miyamoto, J Okamura, L D. Shultz, and M Harada
Quantitative trait loci analysis for plasma HDL-cholesterol concentrations and atherosclerosis susceptibility between inbred mouse strains C57BL/6J and 129S1/SvImJ., N Ishimori, R Li, P M. Kelmenson, R Korstanje, K A. Walsh, G A. Churchill, Semb K. Forsman, and B Paigen
Quantitative trait loci that determine plasma lipids and obesity in C57BL/6J and 129S1/SvImJ inbred mice., N Ishimori, R Li, P M. Kelmenson, R Korstanje, K A. Walsh, G A. Churchill, Semb K. Forsman, and B Paigen
The ldis1 lens mutation in RIIIS/J mice maps to chromosome 8 near cadherin 1., M M. Jablonski, L Lu, X Wang, E J. Chesler, E Carps, S Qi, J Gu, and R W. Williams
Selective phenotyping for increased efficiency in genetic mapping studies., C Jin, H Lan, A D. Attie, G A. Churchill, D Bulutuglo, and B S. Yandell
Gravity receptor function in mice with graded otoconial deficiencies., S M. Jones, L C. Erway, K R. Johnson, H Yu, and T A. Jones
Genetically linked site-specificity of disuse osteoporosis., S Judex, R Garman, M Squire, B Busa, L R. Donahue, and C Rubin
Genetically based influences on the site-specific regulation of trabecular and cortical bone morphology., S Judex, R Garman, M Squire, L R. Donahue, and C Rubin
Age-related hearing loss and the ahl locus in mice., E M. Keithley, C Canto, Q Y. Zheng, Ghodsian N. Fischel, and K R. Johnson
Stabilization of beta-catenin in the mouse zygote leads to premature epithelial-mesenchymal transition in the epiblast., R Kemler, A Hierholzer, B Kanzler, S Kuppig, K Hansen, M M. Taketo, Vries W. de, B B. Knowles, and D Solter
Mapping of a quantitative trait locus for morphine withdrawal severity., B Kest, C A. Palmese, A Juni, E J. Chesler, and J S. Mogil
Genetic and phenotypic analysis of seizure susceptibility in PL/J mice., T Kitami, S Ernest, L Gallaugher, L Friedman, W N. Frankel, and J H. Nadeau
Dual effect of p53 on radiation sensitivity in vivo: p53 promotes hematopoietic injury, but protects from gastro-intestinal syndrome in mice., E A. Komarova, R V. Kondratov, K Wang, K Christov, T V. Golovkina, J R. Goldblum, and A V. Gudkov
Quantitative trait locus mapping of genes that regulate phospholipid transfer activity in SM/J and NZB/BlNJ inbred mice., R Korstanje, J J. Albers, G Wolfbauer, R Li, A Y. Tu, G A. Churchill, and Beverly J. Paigen
Unraveling the genetics of chronic kidney disease using animal models., R Korstanje and K DiPetrillo
Locating Ath8, a locus for murine atherosclerosis susceptibility and testing several of its candidate genes in mice and humans., R Korstanje, P Eriksson, A Samnegard, P G. Olsson, Semb K. Forsman, S Sen, G A. Churchill, J Rollins, S Harris, A Hamsten, and B Paigen
Influence of sex and diet on quantitative trait loci for HDL cholesterol levels in an SM/J by NZB/BlNJ intercross population., R Korstanje, R Li, T Howard, P Kelmenson, J Marshall, B Paigen, and G Churchill
Contributions of dysregulated energy metabolism to type 2 diabetes development in NZO/H1Lt mice with polygenic obesity., R A. Koza, K Flurkey, D M. Graunke, C Braun, H J. Pan, P C. Reifsnyder, L P. Kozak, and E H. Leiter
Mouse development and cell proliferation in the absence of D-cyclins., K Kozar, M A. Ciemerych, V I. Rebel, H Shigematsu, A Zagozdzon, E Sicinska, Y Geng, Q Yu, S Bhattacharya, R T. Bronson, K Akashi, and P Sicinski
Haploinsufficient lethality and formation of arteriovenous malformations in Notch pathway mutants., L T. Krebs, J R. Shutter, K Tanigaki, T Honjo, K L. Stark, and T Gridley
Liver-specific expression of the agouti gene in transgenic mice promotes liver carcinogenesis in the absence of obesity and diabetes., A I. Kuklin, R L. Mynatt, M L. Klebig, L L. Kiefer, W O. Wilkison, R P. Woychik, and E J. Michaud
A new murine model of humoral immuno-deficiency specifically affects class switching to T-independent antigens., I I. Kuzin, G D. Ugine, R K. Barth, L D. Shultz, M H. Nahm, F M. Young, and A Bottaro
Spontaneous cholecysto- and hepatolithiasis in Mdr2-/- mice: a model for low phospholipid-associated cholelithiasis., F Lammert, D Q. Wang, S Hillebrandt, A Geier, P Fickert, M Trauner, S Matern, B Paigen, and M C. Carey
Overexpression of c-MYC promotes an undifferentiated phenotype in cultured astrocytes and allows elevated Ras and Akt signaling to induce gliomas from GFAP-expressing cells in mice., A B. Lassman, C Dai, G N. Fuller, A J. Vickers, and E C. Holland
Stage-dependent effects of oocytes and growth differentiation factor 9 on mouse granulosa cell development: advance programming and subsequent control of the transition from preantral secondary follicles to early antral tertiary follicles., K E. Latham, K Wigglesworth, M McMenamin, and J J. Eppig
Differential levels of diabetogenic stress in two new mouse models of obesity and type 2 diabetes., E H. Leiter and P C. Reifsnyder
Animal models have little to teach us about type 1 diabetes: 2. In opposition to this proposal., E H. Leiter and Herrath von
New mouse genetic models for human contraceptive development., C Lessard, J K. Pendola, S A. Hartford, J C. Schimenti, M A. Handel, and J J. Eppig
A dynamic switch in Rb+/- mediated neuroendocrine tumorigenesis., S W. Leung, E H. Wloga, A F. Castro, T Nguyen, R T. Bronson, and L Yamasaki
Individual nonobese diabetic mice exhibit unique patterns of CD8+ T cell reactivity to three islet antigens, including the newly identified widely expressed dystrophia myotonica kinase., S M. Lieberman, T Takaki, B Han, P Santamaria, D V. Serreze, and T P. DiLorenzo
Intraocular pressure in zebrafish: comparison of inbred strains and identification of a reduced melanin mutant with raised IOP., B A. Link, M P. Gray, R S. Smith, and S W. John
Reductions in linker histone levels are tolerated in developing spermatocytes but cause changes in specific gene expression., Q Lin, A Inselman, X Han, H Xu, W Zhang, M A. Handel, and A I. Skoultchi
The effect of dietary glutathione and coenzyme Q10 on the prevention and treatment of inflammatory bowel disease in mice., C Liu, R M. Russell, D E. Smith, R T. Bronson, P E. Milbury, S Furukawa, X D. Wang, and J B. Blumberg
Exploration of low-dose estrogen effects: identification of No Observed Transcriptional Effect Level (NOTEL)., E K. Lobenhofer, X Cui, L Bennett, P L. Cable, B A. Merrick, G A. Churchill, and C A. Afshari
Loss of NFAT5 results in renal atrophy and lack of tonicity-responsive gene expression., Rodriguez C. Lopez, C L. Antos, J M. Shelton, J A. Richardson, F Lin, T I. Novobrantseva, R T. Bronson, P Igarashi, A Rao, and E N. Olson
New intragenic deletions in the Phex gene clarify X-linked hypophosphatemia-related abnormalities in mice., Depiereux B. Lorenz, V E. Guido, K R. Johnson, Q Y. Zheng, L H. Gagnon, J D. Bauschatz, M T. Davisson, L L. Washburn, L R. Donahue, T M. Strom, and E M. Eicher
Scd1ab-Xyk: a new asebia allele characterized by a CCC trinucleotide insertion in exon 5 of the stearoyl-CoA desaturase 1 gene in mouse., Y Lu, L Bu, S Zhou, M Jin, J P. Sundberg, H Jiang, M Qian, Y Shi, G Zhao, X Kong, and L Hu
Genetic contributors to lipoprotein cholesterol levels in an intercross of 129S1/SvImJ and RIIIS/J inbred mice., M A. Lyons, R Korstanje, R Li, K A. Walsh, G A. Churchill, M C. Carey, and B Paigen
Quantitative trait loci that determine lipoprotein cholesterol levels in an intercross of 129S1/SvImJ and CAST/Ei inbred mice., M A. Lyons, H Wittenburg, R Li, K A. Walsh, R Korstanje, G A. Churchill, M C. Carey, and B Paigen
Transgenic rescue of neurogenic atrophy in the nmd mouse reveals a role for Ighmbp2 in dilated cardiomyopathy., T P. Maddatu, S M. Garvey, D G. Schroeder, T G. Hampton, and G A. Cox
Altered oxidative stress response of the long-lived Snell dwarf mouse., M A. Madsen, C C. Hsieh, W H. Boylston, K Flurkey, D Harrison, and J Papaconstantinou
The inner nuclear membrane protein lamin B receptor forms distinct microdomains and links epigenetically marked chromatin to the nuclear envelope., D Makatsori, N Kourmouli, H Polioudaki, L D. Shultz, K McLean, P A. Theodoropoulos, P B. Singh, and S D. Georgatos
Meiosis-activating sterol promotes the metaphase I to metaphase II transition and preimplantation developmental competence of mouse oocytes maturing in vitro., Bivens C. Marin, C Grondahl, A Murray, T Blume, Y Q. Su, and J J. Eppig
A synthetic analogue of meiosis-activating sterol (FF-MAS) is a potent agonist promoting meiotic maturation and preimplantation development of mouse oocytes maturing in vitro., Bivens C. Marin, B Lindenthal, M J. O'Brien, K Wigglesworth, T Blume, C Grondahl, and J J. Eppig
Evaluation of donor-specific transfusion sources: unique failure of bone marrow cells to induce prolonged skin allograft survival with anti-CD154 monoclonal antibody., T G. Markees, T Pearson, A Cuthbert, A L. Pearson, L D. Shultz, J Leif, N E. Phillips, J P. Mordes, D L. Greiner, and A A. Rossini
Telomeres and the DNA damage response: why the fox is guarding the henhouse., R S. Maser and R A. DePinho
ALS/Lt: a new type 2 diabetes mouse model associated with low free radical scavenging potential., C E. Mathews, R Bagley, and E H. Leiter
Anti-insulin receptor autoantibodies are not required for type 2 diabetes pathogenesis in NZL/Lt mice, a New Zealand obese (NZO)-derived mouse strain., M F. McInerney, S M. Najjar, D Brickley, M Lutzke, Rjaily G. Abou, P Reifsnyder, B D. Haskell, K Flurkey, Y J. Zhang, S L. Pietropaolo, M Pietropaolo, J P. Byers, and E H. Leiter
FOXN1 is critical for onycholemmal terminal differentiation in nude (Foxn1) mice., L Mecklenburg, R Paus, Z Halata, L S. Bechtold, P Fleckman, and J P. Sundberg