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Submissions from 2006

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GOLEM: an interactive graph-based gene-ontology navigation and analysis tool., R S. Sealfon, M A. Hibbs, C Huttenhower, C L. Myers, and O G. Troyanskaya

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An active dominant mutation of glycyl-tRNA synthetase causes neuropathy in a Charcot-Marie-Tooth 2D mouse model., K L. Seburn, L A. Nangle, G A. Cox, P Schimmel, and R W. Burgess

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Partial versus full allogeneic hemopoietic chimerization is a preferential means to inhibit type 1 diabetes as the latter induces generalized immunosuppression., D V. Serreze, M A. Osborne, Y G. Chen, H D. Chapman, T Pearson, M A. Brehm, and D L. Greiner

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Pathway to totipotency: lessons from germ cells., G Seydoux and R E. Braun

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Abnormal lymphoid organ development in immunodeficient mutant mice., R Seymour, J P. Sundberg, and H Hogenesch

Mitoferrin is essential for erythroid iron assimilation., G C. Shaw, J J. Cope, L Li, K Corson, C Hersey, G E. Ackermann, B Gwynn, A J. Lambert, R A. Wingert, D Traver, Y Zhou, E Minet, A Donovan, A Brownlie, R Balzan, M J. Weiss, L L. Peters, J Kaplan, and L I. Zon

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A rostrocaudal muscular dystrophy caused by a defect in choline kinase beta, the first enzyme in phosphatidylcholine biosynthesis., R B. Sher, C Aoyama, K A. Huebsch, S Ji, J Kerner, Y Yang, W N. Frankel, C L. Hoppel, P A. Wood, D E. Vance, and G A. Cox

Nuclear receptor coactivator-3 alleles are associated with serum bioavailable testosterone, insulin-like growth factor-1, and vertebral bone mass in men., Y T. Sheu, J M. Zmuda, J A. Cauley, S P. Moffett, C J. Rosen, C Ishwad, and R E. Ferrell

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Gene expression analysis of mouse chromosome substitution strains., K R. Shockley and G A. Churchill

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Folding and organization of a contiguous chromosome region according to the gene distribution pattern in primary genomic sequence., L S. Shopland, C R. Lynch, K A. Peterson, K Thornton, N Kepper, J Hase, S Stein, S Vincent, K R. Molloy, G Kreth, C Cremer, C J. Bult, and T P. O'Brien

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Genes within the Idd5 and Idd9/11 diabetes susceptibility loci affect the pathogenic activity of B cells in nonobese diabetic mice., P A. Silveira, H D. Chapman, J Stolp, E Johnson, S L. Cox, K Hunter, L S. Wicker, and D V. Serreze

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Mutations in the gene encoding the low-density lipoprotein receptor LRP4 cause abnormal limb development in the mouse., Chazottes D. Simon, S Tutois, M Kuehn, M Evans, F Bourgade, S Cook, M T. Davisson, and J L. Guenet

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Telomere shortening and mood disorders: preliminary support for a chronic stress model of accelerated aging., N M. Simon, J W. Smoller, K L. McNamara, R S. Maser, A K. Zalta, M H. Pollack, A A. Nierenberg, M Fava, and K K. Wong

Adherence to bisphosphonate therapy and fracture rates in osteoporotic women: relationship to vertebral and nonvertebral fractures from 2 US claims databases., E S. Siris, S T. Harris, C J. Rosen, C E. Barr, J N. Arvesen, T A. Abbott, and S Silverman

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Genetic analysis of the stress-responsive adrenocortical axis., L C. Solberg, A E. Baum, N Ahmadiyeh, K Shimomura, R Li, F W. Turek, J S. Takahashi, G A. Churchill, and E E. Redei

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From teratocarcinomas to embryonic stem cells and beyond: a history of embryonic stem cell research., D Solter

Imprinting today: end of the beginning or beginning of the end?, D Solter

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Absence of erythroblast macrophage protein (Emp) leads to failure of erythroblast nuclear extrusion., S Soni, S Bala, B Gwynn, K E. Sahr, L L. Peters, and M Hanspal

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Quantitative trait locus analysis for obesity reveals multiple networks of interacting loci., I M. Stylianou, R Korstanje, R Li, S Sheehan, B Paigen, and G A. Churchill

Comparative genomics of asthma., I M. Stylianou, J Singh, D A. Schwartz, and B Paigen

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Complex genetic architecture revealed by analysis of high-density lipoprotein cholesterol in chromosome substitution strains and F2 crosses., I M. Stylianou, S W. Tsaih, K DiPetrillo, N Ishimori, R Li, B Paigen, and G Churchill

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p63 protects the female germ line during meiotic arrest., E K. Suh, A Yang, A Kettenbach, C Bamberger, A H. Michaelis, Z Zhu, J A. Elvin, R T. Bronson, C P. Crum, and F McKeon

Professional use of mutant laboratory mice in research., J P. Sundberg and C J. Bult

Common diseases found in inbred strains of laboratory mice., Sundberg JP, Ichiki T

Phenotyping postpartum mutant laboratorymice and determining their value for human diseases., Sundberg JP, Ichiki T

Genetically engineered mice: past, present and future, Sundberg JP, Ichiki T, Ward JM, Rozell B

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Sequences within the gag gene of mouse mammary tumor virus needed for mammary gland cell transformation., I Swanson, B A. Jude, A R. Zhang, A Pucker, Z E. Smith, and T V. Golovkina

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Know thy mouse., R A. Taft, M Davisson, and M V. Wiles

Nras loss induces metastatic conversion of Rb1-deficient neuroendocrine thyroid tumor., C Takahashi, B Contreras, T Iwanaga, Y Takegami, A Bakker, R T. Bronson, M Noda, M Loda, J L. Hunt, and M E. Ewen

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HLA-A*0201-restricted T cells from humanized NOD mice recognize autoantigens of potential clinical relevance to type 1 diabetes., T Takaki, M P. Marron, C E. Mathews, S T. Guttmann, R Bottino, M Trucco, T P. DiLorenzo, and D V. Serreze

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The leukotriene B4 receptor (BLT1) is required for effector CD8+ T cell-mediated, mast cell-dependent airway hyperresponsiveness., C Taube, N Miyahara, V Ott, B Swanson, K Takeda, J Loader, L D. Shultz, A M. Tager, A D. Luster, A Dakhama, and E W. Gelfand

TLR agonists abrogate costimulation blockade-induced prolongation of skin allografts., T B. Thornley, M A. Brehm, T G. Markees, L D. Shultz, J P. Mordes, R M. Welsh, A A. Rossini, and D L. Greiner

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Nmf11 is a novel ENU-induced mutation in the mouse glycine receptor alpha 1 subunit., M Traka, K L. Seburn, and B Popko

EUK-8, a superoxide dismutase and catalase mimetic, reduces cardiac oxidative stress and ameliorates pressure overload-induced heart failure in the harlequin mouse mutant., Empel V. van, A T. Bertrand, Oort R. van, der Nagel van, M Engelen, Rijen H. van, P A. Doevendans, H J. Crijns, S L. Ackerman, W Sluiter, and Windt L. De

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Extracting gene networks for low-dose radiation using graph theoretical algorithms., B H. Voy, J A. Scharff, A D. Perkins, A M. Saxton, B Borate, E J. Chesler, L K. Branstetter, and M A. Langston

T-cell co-stimulators as anti-inflammatory targets for atherosclerotic disease., X Wang

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Defective carbohydrate metabolism in mice homozygous for the tubby mutation., Y Wang, K Seburn, L Bechtel, B Y. Lee, J P. Szatkiewicz, P M. Nishina, and J K. Naggert

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Dorsally derived netrin 1 provides an inhibitory cue and elaborates the ;waiting period' for primary sensory axons in the developing spinal cord., K Watanabe, N Tamamaki, T Furuta, S L. Ackerman, K Ikenaka, and K Ono

Femur mechanical properties in the F2 progeny of an NZB/B1NJ x RF/J cross are regulated predominantly by genetic loci that regulate bone geometry., J E. Wergedal, Bicknell C. Ackert, S W. Tsaih, M H. Sheng, R Li, S Mohan, W G. Beamer, G A. Churchill, and D J. Baylink

Controlling the differentiation of mouse ES cells in vitro., Wiles MV, Proetzel G

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Effects of exposing DBA/2J mice to a high-frequency augmented acoustic environment on the cochlea and anteroventral cochlear nucleus., J F. Willott, J V. Bosch, T Shimizu, and D L. Ding

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Effects of exposing gonadectomized and intact C57BL/6J mice to a high-frequency augmented acoustic environment: Auditory brainstem response thresholds and cytocochleograms., J F. Willott, J VandenBosche, T Shimizu, D L. Ding, and R Salvi

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QTL mapping for genetic determinants of lipoprotein cholesterol levels in combined crosses of inbred mouse strains., H Wittenburg, M A. Lyons, R Li, U Kurtz, X Wang, J Mossner, G A. Churchill, M C. Carey, and B Paigen

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Low-level mechanical vibrations can influence bone resorption and bone formation in the growing skeleton., L Xie, J M. Jacobson, E S. Choi, B Busa, L R. Donahue, L M. Miller, C T. Rubin, and S Judex

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DCC-dependent phospholipase C signaling in netrin-1-induced neurite elongation., Y Xie, Y Hong, X Y. Ma, X R. Ren, S Ackerman, L Mei, and W C. Xiong

A natural language processing (NLP) tool to assist in the curation of the laboratory Mouse Tumor Biology Database., H Xu, D Krupke, J Blake, and C Friedman

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Not all lunatic fringe null female mice are infertile., J Xu, C R. Norton, and T Gridley

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The ternary IGF complex influences postnatal bone acquisition and the skeletal response to intermittent parathyroid hormone., S Yakar, M L. Bouxsein, E Canalis, H Sun, V Glatt, C Gundberg, P Cohen, D Hwang, Y Boisclair, D Leroith, and C J. Rosen

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Interaction between fidgetin and protein kinase A-anchoring protein AKAP95 is critical for palatogenesis in the mouse., Y Yang, C L. Mahaffey, N Berube, and W N. Frankel

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In vivo role of ER-associated peptidase activity in tailoring peptides for presentation by MHC class Ia and class Ib molecules., J Yan, V V. Parekh, Fernandez Y. Mendez, Villagomez D. Olivares, S Dragovic, T Hill, D C. Roopenian, S Joyce, and Kaer L. Van

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Pten deficiency activates distinct downstream signaling pathways in a tissue-specific manner., L I. Yoo, D W. Liu, V u. Le, R T. Bronson, H Wu, and J Yuan

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Neonatal Fc receptor for IgG regulates mucosal immune responses to luminal bacteria., M Yoshida, K Kobayashi, T T. Kuo, L Bry, J N. Glickman, S M. Claypool, A Kaser, T Nagaishi, D E. Higgins, E Mizoguchi, Y Wakatsuki, D C. Roopenian, A Mizoguchi, W I. Lencer, and R S. Blumberg

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Constant rate of steady-state self-antigen trafficking from skin to regional lymph nodes., M Yoshino, H Yamazaki, L D. Shultz, and S Hayashi

Altered growth characteristics of skin fibroblasts from wild-derived mice, and genetic loci regulating fibroblast clone size., R Yuan, K Flurkey, Aelst Bouma Van, W Zhang, B King, S Austad, R A. Miller, and D E. Harrison

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Helicobacter pylori infection in the pharynx of patients with chronic pharyngitis detected with TDI-FP and modified Giemsa stain., J P. Zhang, Z H. Peng, J Zhang, X H. Zhang, and Q Y. Zheng

Canadian Association of Neurosciences review: postnatal development of the mammalian neocortex: role of activity revisited., Z W. Zhang

Developmental refinement in the mammalian thalamus., Z W. Zhang

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Endoplasmic reticulum stress in health and disease., L Zhao and S L. Ackerman

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Mouse models as a tool to unravel the genetic basis for human otitis media., Q Y. Zheng, Hughes R. Hardisty, and S D. Brown

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Inner ear proteomics of mouse models for deafness, a discovery strategy., Q Y. Zheng, C R. Rozanas, I Thalmann, M R. Chance, and K N. Alagramam

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A new spontaneous mutation in the mouse protocadherin 15 gene., Q Y. Zheng, H Yu, J L. Washington, L B. Kisley, Y S. Kikkawa, K S. Pawlowski, C G. Wright, and K N. Alagramam

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Targeting gastrin-releasing peptide receptors on small cell lung cancer cells with a bispecific molecule that activates polyclonal T lymphocytes., J Zhou, J Chen, R Zhong, M Mokotoff, L D. Shultz, and E D. Ball

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Auditory brainstem responses in 10 inbred strains of mice., X Zhou, P H. Jen, K L. Seburn, W N. Frankel, and Q Y. Zheng

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Multiple mechanisms limit the duration of wakefulness in Drosophila brain., J E. Zimmerman, W Rizzo, K R. Shockley, D M. Raizen, N Naidoo, M Mackiewicz, G A. Churchill, and A I. Pack

Submissions from 2005

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The transcriptional landscape of the mammalian genome.

Interacting genetic loci cause airway hyperresponsiveness., K G. Ackerman, H Huang, H Grasemann, C Puma, J B. Singer, A E. Hill, E Lander, J H. Nadeau, G A. Churchill, J M. Drazen, and D R. Beier

Lineage is an epigenetic modifier of QTL influencing behavioral coping with stress., N Ahmadiyeh, G A. Churchill, L C. Solberg, A E. Baum, K Shimomura, J S. Takahashi, and E E. Redei

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High-dose radiation with bone marrow transfer prevents neurodegeneration in an inherited glaucoma., M G. Anderson, R T. Libby, D B. Gould, R S. Smith, and S W. John

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Brain lipid-binding protein is a direct target of Notch signaling in radial glial cells., T E. Anthony, H A. Mason, T Gridley, G Fishell, and N Heintz

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Coxsackievirus and adenovirus receptor is essential for cardiomyocyte development., D R. Asher, A M. Cerny, S R. Weiler, J W. Horner, M L. Keeler, M A. Neptune, S N. Jones, R T. Bronson, R A. Depinho, and R W. Finberg

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Targeted deletion of the sciellin gene resulted in normal development and maturation., H P. Baden, M F. Champliaud, J P. Sundberg, and A Viel

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Computational, integrative, and comparative methods for the elucidation of genetic coexpression networks., N E. Baldwin, E J. Chesler, S Kirov, M A. Langston, J R. Snoddy, R W. Williams, and B Zhang

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High incidence, early onset of histiocytic sarcomas in mice with Hertwig's anemia., J E. Barker, S A. Deveau, S T. Compton, K Fancher, and J T. Eppig

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Cdcs1, a major colitogenic locus in mice, regulates innate and adaptive immune response to enteric bacterial antigens., J Beckwith, Y Cong, J P. Sundberg, C O. Elson, and E H. Leiter

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Genetics of body weight in the LXS recombinant inbred mouse strains., B Bennett, Link P. Carosone, L Lu, E J. Chesler, and T E. Johnson

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One year of alendronate after one year of parathyroid hormone (1-84) for osteoporosis., D M. Black, J P. Bilezikian, K E. Ensrud, S L. Greenspan, L Palermo, T Hue, T F. Lang, J A. McGowan, and C J. Rosen

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Gonadal sex reversal in mutant Dax1 XY mice: a failure to upregulate Sox9 in pre-Sertoli cells., G J. Bouma, K H. Albrecht, L L. Washburn, A K. Recknagel, G A. Churchill, and E M. Eicher

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PACdb: PolyA Cleavage Site and 3'-UTR Database., J M. Brockman, P Singh, D Liu, S Quinlan, J Salisbury, and J H. Graber

Searching QTL by gene expression: analysis of diabesity., A C. Brown, W I. Olver, C J. Donnelly, M E. May, J K. Naggert, D J. Shaffer, and D C. Roopenian

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Uncovering regulatory pathways that affect hematopoietic stem cell function using 'genetical genomics'., L Bystrykh, E Weersing, B Dontje, S Sutton, A I. Su, E Vellenga, J Wang, K F. Manly, L Lu, E J. Chesler, and al et

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Inferring network interactions within a cell., G W. Carter

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Molecular and cellular basis of the retrovirus resistance in I/LnJ mice., L K. Case, A Purdy, and T V. Golovkina

Mouse models of ocular diseases., B Chang, N L. Hawes, R E. Hurd, J Wang, D Howell, M T. Davisson, T H. Roderick, S Nusinowitz, and J R. Heckenlively

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"Agouti NOD": identification of a CBA-derived Idd locus on Chromosome 7 and its use for chimera production with NOD embryonic stem cells., J Chen, P C. Reifsnyder, F Scheuplein, W H. Schott, M Mileikovsky, Karamath S. Soodeen, A Nagy, M H. Dosch, J Ellis, Nolte F. Koch, and E H. Leiter

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Activated NKT cells inhibit autoimmune diabetes through tolerogenic recruitment of dendritic cells to pancreatic lymph nodes., Y G. Chen, Rossi C. Choisy, T M. Holl, H D. Chapman, G S. Besra, S A. Porcelli, D J. Shaffer, D Roopenian, S B. Wilson, and D V. Serreze

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Complex trait analysis of gene expression uncovers polygenic and pleiotropic networks that modulate nervous system function., E J. Chesler, L Lu, S Shou, Y Qu, J Gu, J Wang, H C. Hsu, J D. Mountz, N E. Baldwin, M A. Langston, D W. Threadgill, K F. Manly, and R W. Williams

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Meiotic messenger RNA and noncoding RNA targets of the RNA-binding protein Translin (TSN) in mouse testis., Y S. Cho, N Iguchi, J Yang, M A. Handel, and N B. Hecht

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Alms1-disrupted mice recapitulate human Alstrom syndrome., G B. Collin, E Cyr, R Bronson, J D. Marshall, E J. Gifford, W Hicks, S A. Murray, Q Y. Zheng, R S. Smith, P M. Nishina, and J K. Naggert

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Genetic modifiers interact with Cpefat to affect body weight, adiposity, and hyperglycemia., G B. Collin, T P. Maddatu, S Sen, and J K. Naggert

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Disruption of murine Tenr results in teratospermia and male infertility., C M. Connolly, A T. Dearth, and R E. Braun

Improved statistical tests for differential gene expression by shrinking variance components estimates., X Cui, J T. Hwang, J Qiu, N J. Blades, and G A. Churchill

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Spontaneous corneal hem- and lymphangiogenesis in mice with destrin-mutation depend on VEGFR3 signaling., C Cursiefen, S Ikeda, P M. Nishina, R S. Smith, A Ikeda, D Jackson, J S. Mo, L Chen, M R. Dana, B Pytowski, F E. Kruse, and J W. Streilein

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The characteristics of astrocytomas and oligodendrogliomas are caused by two distinct and interchangeable signaling formats., C Dai, Y Lyustikman, A Shih, X Hu, G N. Fuller, M Rosenblum, and E C. Holland

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HSP90: a rising star on the horizon of anticancer targets., C Dai and L Whitesell

Discovery genetics: serendipity in basic research., M T. Davisson

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Mouse models of Down syndrome., M T. Davisson

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Evidence for a protective role of the Gardos channel against hemolysis in murine spherocytosis., Franceschi L. De, A Rivera, M D. Fleming, M Honczarenko, L L. Peters, P Gascard, N Mohandas, and C Brugnara

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The good turned ugly: immunopathogenic basis for diabetogenic CD8+ T cells in NOD mice., T P. DiLorenzo and D V. Serreze

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Bioinformatics toolbox for narrowing rodent quantitative trait loci., K DiPetrillo, X Wang, I M. Stylianou, and B Paigen

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A procedure for assessing GO annotation consistency., M E. Dolan, L Ni, E Camon, and J A. Blake