Submissions from 2007
Large-scale genome-wide linkage analysis for loci linked to BMD at different skeletal sites in extreme selected sibships., Y H. Hsu, X Xu, H A. Terwedow, T Niu, X Hong, D Wu, L Wang, J D. Brain, M L. Bouxsein, S R. Cummings, C J. Rosen, and X Xu
Nearest Neighbor Networks: clustering expression data based on gene neighborhoods., C Huttenhower, A I. Flamholz, J N. Landis, S Sahi, C L. Myers, K L. Olszewski, M A. Hibbs, N O. Siemers, O G. Troyanskaya, and H A. Coller
The developmental program of human dendritic cells is operated independently of conventional myeloid and lymphoid pathways., F Ishikawa, H Niiro, T Iino, S Yoshida, N Saito, S Onohara, T Miyamoto, H Minagawa, S Fujii, L D. Shultz, M Harada, and K Akashi
Chemotherapy-resistant human AML stem cells home to and engraft within the bone-marrow endosteal region., F Ishikawa, S Yoshida, Y Saito, A Hijikata, M Fukata, T Miyamoto, B Lyons, K Ohshima, K Akashi, M Harada, L D. Shultz, and al et
In vivo cytotoxicity of insulin-specific CD8+ T-cells in HLA-A*0201 transgenic NOD mice., I Jarchum, J C. Baker, T Yamada, T Takaki, M P. Marron, D V. Serreze, and T P. DiLorenzo
Quantitative trait loci that determine mouse tibial nanoindentation properties in an F2 population derived from C57BL/6J x C3H/HeJ., Y Jiao, H Chiu, Z Fan, F Jiao, E C. Eckstein, W G. Beamer, and W Gu
A single nucleotide mutation in Nppc is associated with a long bone abnormality in lbab mice., Y Jiao, J Yan, F Jiao, H Yang, L R. Donahue, X Li, B A. Roe, J Stuart, and W Gu
LKB1 modulates lung cancer differentiation and metastasis., H Ji, M R. Ramsey, D N. Hayes, C Fan, K McNamara, P Kozlowski, M C. Liang, J Koivunen, L R. Chirieac, R F. Padera, R T. Bronson, and al et
Mutations in BRAF and KRAS converge on activation of the mitogen-activated protein kinase pathway in lung cancer mouse models., H Ji, Z Wang, S A. Perera, D Li, M C. Liang, S Zaghlul, K McNamara, L Chen, L R. Chirieac, R Padera, R T. Bronson, R K. Thomas, and al et
Congenital hypothyroidism, dwarfism, and hearing impairment caused by a missense mutation in the mouse dual oxidase 2 gene, Duox2., K R. Johnson, C C. Marden, Bailey P. Ward, L H. Gagnon, R T. Bronson, and L R. Donahue
Gene replacement reveals a specific role for E-cadherin in the formation of a functional trophectoderm., N G. Kan, M P. Stemmler, D Junghans, B Kanzler, Vries W. de, M Dominis, and R Kemler
Dietary thyroid hormone replacement ameliorates hearing deficits in hypothyroid mice., I J. Karolyi, G A. Dootz, K Halsey, L Beyer, F J. Probst, K R. Johnson, A F. Parlow, Y Raphael, D F. Dolan, and S A. Camper
Ability of herpes simplex virus vectors to boost immune responses to DNA vectors and to protect against challenge by simian immunodeficiency virus., A Kaur, H B. Sanford, D Garry, S Lang, S A. Klumpp, D Watanabe, R T. Bronson, J D. Lifson, M Rosati, G N. Pavlakis, B K. Felber, D M. Knipe, and R C. Desrosiers
The presynaptic CaV2.2 channel-transmitter release site core complex., R Khanna, Q Li, J Bewersdorf, and E F. Stanley
A revised nomenclature for the human and rodent alpha-tubulin gene family., V K. Khodiyar, L J. Maltais, K M. Sneddon, J R. Smith, M Shimoyama, F Cabral, C Dumontet, S K. Dutcher, R J. Harvey, L Lafanechere, J M. Murray, E Nogales, D Piquemal, F Stanchi, S Povey, and R C. Lovering
Genetic background modifies inner ear and eye phenotypes of jag1 heterozygous mice., A E. Kiernan, R Li, N L. Hawes, G A. Churchill, and T Gridley
A mouse model of conditional lipodystrophy., S Kim, L W. Huang, K J. Snow, V Ablamunits, M G. Hasham, T H. Young, A C. Paulk, J E. Richardson, J P. Affourtit, Barak T. Shalom, C J. Bult, and Y Barak
Development of new-generation HU-PBMC-NOD/SCID mice to study human islet alloreactivity., M King, T Pearson, L D. Shultz, J Leif, R Bottino, M Trucco, M Atkinson, C Wasserfall, K Herold, J P. Mordes, A A. Rossini, and D L. Greiner
A spatially and temporally restricted mouse model of soft tissue sarcoma., D G. Kirsch, D M. Dinulescu, J B. Miller, J Grimm, P M. Santiago, N P. Young, G P. Nielsen, C P. Schultz, O Takeuchi, R T. Bronson, D Crowley, F J. Hornicek, and al et
Automated compartmental analysis for high-throughput skeletal phenotyping in femora of genetic mouse models., T Kohler, M Stauber, L R. Donahue, and R Muller
Ena/VASP Is Required for neuritogenesis in the developing cortex., A V. Kwiatkowski, D A. Rubinson, E W. Dent, Veen J. van, J D. Leslie, J Zhang, L M. Mebane, U Philippar, E M. Pinheiro, A A. Burds, R T. Bronson, S Mori, R Fassler, and F B. Gertler
Ulcerative colitis and autoimmunity induced by loss of myeloid alphav integrins., Hulbert A. Lacy, A M. Smith, H Tissire, M Barry, D Crowley, R T. Bronson, J T. Roes, J S. Savill, and R O. Hynes
Activation of peroxisome proliferator-activated receptor gamma (PPARgamma) by rosiglitazone suppresses components of the insulin-like growth factor regulatory system in vitro and in vivo., Czernik B. Lecka, Bicknell C. Ackert, M L. Adamo, V Marmolejos, G A. Churchill, K R. Shockley, I R. Reid, A Grey, and C J. Rosen
Adipokine and insulin profiles distinguish diabetogenic and non-diabetogenic obesities in mice., E H. Leiter, P C. Reifsnyder, Q Xiao, and J Mistry
Unexpected functional consequences of xenogeneic transgene expression in beta-cells of NOD mice., E H. Leiter, P Reifsnyder, J Driver, S Kamdar, Rossi C. Choisy, D V. Serreze, M Hara, and A Chervonsky
Mutagenesis-generated mouse models of human infertility with abnormal sperm., C Lessard, H Lothrop, J C. Schimenti, and M A. Handel
Inducible nitric oxide synthase, Nos2, does not mediate optic neuropathy and retinopathy in the DBA/2J glaucoma model., R T. Libby, G R. Howell, I H. Pang, O V. Savinova, A K. Mehalow, J W. Barter, R S. Smith, A F. Clark, and S W. John
Models of signal transduction in cancer., Dongguang Li and Shaoguang Li
Src kinase signaling in leukaemia., S Li
Systematic variation in mRNA 3'-processing signals during mouse spermatogenesis., D Liu, J M. Brockman, B Dass, L N. Hutchins, P Singh, J R. McCarrey, C C. MacDonald, and J H. Graber
NF-kappaB signaling regulates functional expression of the MHC class I-related neonatal Fc receptor for IgG via intronic binding sequences., X Liu, L Ye, G J. Christianson, J Q. Yang, D C. Roopenian, and X Zhu
The near-naked hairless (Hr(N)) mutation disrupts hair formation but is not due to a mutation in the Hairless coding region., Y Liu, S Das, R E. Olszewski, D A. Carpenter, C T. Culiat, J P. Sundberg, P Soteropoulos, X Liu, M J. Doktycz, E J. Michaud, and B H. Voy
ETV6-NTRK3 fusion oncogene initiates breast cancer from committed mammary progenitors via activation of AP1 complex., Z Li, C E. Tognon, F J. Godinho, L Yasaitis, H Hock, J I. Herschkowitz, C L. Lannon, E Cho, S J. Kim, R T. Bronson, C M. Perou, P H. Sorensen, and S H. Orkin
Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation., D B. Lombard, F W. Alt, H L. Cheng, J Bunkenborg, R S. Streeper, R Mostoslavsky, J Kim, G Yancopoulos, D Valenzuela, A Murphy, Y Yang, Y Chen, M D. Hirschey, R T. Bronson, and B Schwer
A missense mutation in the conserved C2B domain of otoferlin causes deafness in a new mouse model of DFNB9., Guess C. Longo, L H. Gagnon, D E. Bergstrom, and K R. Johnson
Targeted knockout and lacZ reporter expression of the mouse Tmhs deafness gene and characterization of the hscy-2J mutation., Guess C. Longo, L H. Gagnon, B Fritzsch, and K R. Johnson
Bile duct proliferation in liver-specific Jag1 conditional knockout mice: effects of gene dosage., K M. Loomes, P Russo, M Ryan, A Nelson, L Underkoffler, C Glover, H Fu, T Gridley, K H. Kaestner, and R J. Oakey
Macromolecule biosynthesis: a key function of sleep., M Mackiewicz, K R. Shockley, M A. Romer, R J. Galante, J E. Zimmerman, N Naidoo, D A. Baldwin, S T. Jensen, G A. Churchill, and A I. Pack
Role of the beta1 subunit in the function and stability of the 20S proteasome in the hyperthermophilic archaeon Pyrococcus furiosus., L S. Madding, J K. Michel, K R. Shockley, S B. Conners, K L. Epting, M R. Johnson, and R M. Kelly
Characterization of the IGF system in 15 patients with Alstrom syndrome., P Maffei, M Boschetti, J D. Marshall, R B. Paisey, S Beck, E Resmini, G B. Collin, J K. Naggert, G Milan, R Vettor, F Minuto, N Sicolo, and A Barreca
Cardiac manifestations of Alstrom syndrome: echocardiographic findings., A N. Makaryus, M E. Zubrow, J D. Marshall, L D. Gillam, and J R. Mangion
Alstrom syndrome., J D. Marshall, S Beck, P Maffei, and J K. Naggert
Spectrum of ALMS1 variants and evaluation of genotype-phenotype correlations in Alstrom syndrome., J D. Marshall, E G. Hinman, G B. Collin, S Beck, R Cerqueira, P Maffei, G Milan, W Zhang, D I. Wilson, T Hearn, P Tavares, R Vettor, C Veronese, M Martin, W V. So, P M. Nishina, and J K. Naggert
Chromosomally unstable mouse tumours have genomic alterations similar to diverse human cancers., R S. Maser, B Choudhury, P J. Campbell, B Feng, K K. Wong, A Protopopov, J O'Neil, A Gutierrez, E Ivanova, I Perna, E Lin, and al et
DNA-dependent protein kinase catalytic subunit is not required for dysfunctional telomere fusion and checkpoint response in the telomerase-deficient mouse., R S. Maser, K K. Wong, E Sahin, H Xia, M Naylor, H M. Hedberg, S E. Artandi, and R A. DePinho
Leptin in autoimmunity: many questions, some answers., G Matarese, E H. Leiter, and Cava A. La
In vivo distribution of human adipose-derived mesenchymal stem cells in novel xenotransplantation models., T E. Meyerrose, Ugarte D. De, A A. Hofling, P E. Herrbrich, T D. Cordonnier, L D. Shultz, J C. Eagon, L Wirthlin, M S. Sands, M A. Hedrick, and J A. Nolta
Gene expression profiling of leukemic cells and primary thymocytes predicts a signature for apoptotic sensitivity to glucocorticoids., A L. Miller, S Komak, M S. Webb, E H. Leiter, and E B. Thompson
An Aging Interventions Testing Program: study design and interim report., R A. Miller, D E. Harrison, C M. Astle, R A. Floyd, K Flurkey, K L. Hensley, M A. Javors, C Leeuwenburgh, J F. Nelson, E Ongini, N L. Nadon, H R. Warner, and R Strong
Imaging axonal transport of mitochondria in vivo., T Misgeld, M Kerschensteiner, F M. Bareyre, R W. Burgess, and J W. Lichtman
The archetypal R90C CADASIL-NOTCH3 mutation retains NOTCH3 function in vivo., M Monet, V Domenga, B Lemaire, C Souilhol, F Langa, C Babinet, T Gridley, Lasserve E. Tournier, Tannoudji M. Cohen, and A Joutel
Multiple functions of Snail family genes during palate development in mice., S A. Murray, K F. Oram, and T Gridley
Bone quality and bone strength in BXH recombinant inbred mice., A H. Ng, S X. Wang, C H. Turner, W G. Beamer, and M D. Grynpas
Genetic ablation of NMDA receptor subunit NR3B in mouse reveals motoneuronal and nonmotoneuronal phenotypes., S Niemann, H Kanki, Y Fukui, K Takao, M Fukaya, M N. Hynynen, M J. Churchill, J M. Shefner, R T. Bronson, R H. Brown, M Watanabe, T Miyakawa, S Itohara, and Y Hayashi
Quantitative trait loci associated with blood pressure of metabolic syndrome in the progeny of NZO/HILtJxC3H/HeJ intercrosses., E Nishihara, S W. Tsaih, C Tsukahara, S Langley, S Sheehan, K DiPetrillo, S Kunita, K Yagami, G A. Churchill, B Paigen, and F Sugiyama
Alu elements mediate MYB gene tandem duplication in human T-ALL., J O'Neil, J Tchinda, A Gutierrez, L Moreau, R S. Maser, K K. Wong, W Li, K McKenna, X S. Liu, B Feng, D Neuberg, and al et
Characterization of HKE2: an ancient antigen encoded in the major histocompatibility complex., D A. Ostrov, C L. Barnes, L E. Smith, S Binns, T M. Brusko, A C. Brown, P S. Quint, S A. Litherland, D C. Roopenian, and K A. Iczkowski
Anti-CD40 conditioning enhances the T(CD8) response to a highly tolerogenic epitope and subsequent immunotherapy of simian virus 40 T antigen-induced pancreatic tumors., P Otahal, B B. Knowles, S S. Tevethia, and T D. Schell
Molecular analysis and long-term clinical evaluation of three siblings with Alstrom syndrome., R K. Ozgul, I Satman, G B. Collin, E G. Hinman, J D. Marshall, O Kocaman, Y Tutuncu, T Yilmaz, and J K. Naggert
Novel method for high-throughput phenotyping of sleep in mice., A I. Pack, R J. Galante, G Maislin, J Cater, D Metaxas, S Lu, L Zhang, Smith R. Von, T Kay, J Lian, K Svenson, and L L. Peters
Genome plasticity in the mouse oocyte and early embryo., A E. Peaston, B B. Knowles, and K W. Hutchison
Inhibition of heat shock protein 90 prolongs survival of mice with BCR-ABL-T315I-induced leukemia and suppresses leukemic stem cells., C Peng, J Brain, Y Hu, A Goodrich, L Kong, D Grayzel, R Pak, M Read, and S Li
Heat shock protein 90: a potential therapeutic target in leukemic progenitor and stem cells harboring mutant BCR-ABL resistant to kinase inhibitors., C Peng, D Li, and S Li
The mouse as a model for human biology: a resource guide for complex trait analysis., L L. Peters, R F. Robledo, C J. Bult, G A. Churchill, B J. Paigen, and K L. Svenson
Crossover interference underlies sex differences in recombination rates., P M. Petkov, K W. Broman, J P. Szatkiewicz, and K Paigen
Evidence of a large-scale functional organization of Mammalian chromosomes., P M. Petkov, J H. Graber, G A. Churchill, K DiPetrillo, B L. King, and K Paigen
Reproductive bology of the laboratory mouse., K R. Pritchett and R A. Taft
Anaplastic, plasmablastic, and plasmacytic plasmacytomas of mice: relationships to human plasma cell neoplasms and late-stage differentiation of normal B cells., C F. Qi, J X. Zhou, C H. Lee, Z Naghashfar, S Xiang, A L. Kovalchuk, T N. Fredrickson, J W. Hartley, D C. Roopenian, W F. Davidson, S Janz, and H C. Morse
Acute but not chronic macrophage recruitment in filarial infections in mice is dependent on C-C chemokine ligand 2., M Ramesh, N Paciorkowski, Y Dash, L Shultz, and T V. Rajan
Herpesvirus saimiri terminal membrane proteins modulate HIV-1 replication by altering Nef and Tat functions., A D. Raymond, M Hasham, A Y. Tsygankov, and E E. Henderson
Ancient papillomavirus-host co-speciation in Felidae., A Rector, P Lemey, R Tachezy, S Mostmans, S J. Ghim, Doorslaer K. Van, M Roelke, M Bush, R J. Montali, J Joslin, R D. Burk, A B. Jenson, J P. Sundberg, B Shapiro, and Ranst M. Van
FcRn: the neonatal Fc receptor comes of age., D C. Roopenian and S Akilesh
Mouse models for understanding the growth hormone insulin-like growth factor-I axis., C J. Rosen
The rosiglitazone story--lessons from an FDA Advisory Committee meeting., C J. Rosen
An informatics approach to systems neurogenetics., G D. Rosen, E J. Chesler, K F. Manly, and R W. Williams
Adipogenesis is inhibited by brief, daily exposure to high-frequency, extremely low-magnitude mechanical signals., C T. Rubin, E Capilla, Y K. Luu, B Busa, H Crawford, D J. Nolan, V Mittal, C J. Rosen, J E. Pessin, and S Judex
Sequential quantitative trait locus mapping in experimental crosses., J M. Satagopan, S Sen, and G A. Churchill
Ligand-activated peroxisome proliferator activated receptor gamma alters placental morphology and placental fatty acid uptake in mice., W T. Schaiff, F F. Knapp, Y Barak, Shental T. Biron, D M. Nelson, and Y Sadovsky
The Fas pathway is involved in pancreatic beta cell secretory function., D M. Schumann, K Maedler, I Franklin, D Konrad, J Storling, Schnetzler M. Boni, A Gjinovci, M O. Kurrer, D Bosco, M Greter, B Becher, A V. Chervonsky, and M Y. Donath
Notch1 expression and ligand interactions in progenitor cells of the mouse olfactory epithelium., G A. Schwarting, T Gridley, and T R. Henion
R/qtlDesign: inbred line cross experimental design., S Sen, J M. Satagopan, K W. Broman, and G A. Churchill
"Humanized" HLA transgenic NOD mice to identify pancreatic beta cell autoantigens of potential clinical relevance to type 1 diabetes., D V. Serreze, M P. Marron, and T P. Dilorenzo
Spontaneous mutations in the mouse Sharpin gene result in multiorgan inflammation, immune system dysregulation and dermatitis., R E. Seymour, M G. Hasham, G A. Cox, L D. Shultz, H Hogenesch, D C. Roopenian, and J P. Sundberg
Heterozygous kit mutants with little or no apparent anemia exhibit large defects in overall hematopoietic stem cell function., Y Sharma, C M. Astle, and D E. Harrison
Survival and function of MiHA epitope-specific host CD8 TM cells following ablative conditioning and HCT., A M. Shatry, D C. Roopenian, and R B. Levy
Sprouty-2 regulates oncogenic K-ras in lung development and tumorigenesis., A T. Shaw, A Meissner, J A. Dowdle, D Crowley, M Magendantz, C Ouyang, T Parisi, J Rajagopal, L J. Blank, R T. Bronson, J R. Stone, D A. Tuveson, R Jaenisch, and T Jacks
Different evolutionary histories of the two classical class I genes BF1 and BF2 illustrate drift and selection within the stable MHC haplotypes of chickens., I Shaw, T J. Powell, D A. Marston, K Baker, Hateren A. van, P Riegert, M V. Wiles, S Milne, S Beck, and J Kaufman
Genetic analysis of albuminuria in a cross between C57BL/6J and DBA/2J mice., S Sheehan, S W. Tsaih, B L. King, C Stanton, G A. Churchill, B Paigen, and K DiPetrillo
A viable allele of Mcm4 causes chromosome instability and mammary adenocarcinomas in mice., N Shima, A Alcaraz, I Liachko, T R. Buske, C A. Andrews, R J. Munroe, S A. Hartford, B K. Tye, and J C. Schimenti
Role of novel protein kinase C isoforms in Lyme arthritis., O S. Shin, A K. Behera, R T. Bronson, and L T. Hu
Humanized mice in translational biomedical research., L D. Shultz, F Ishikawa, and D L. Greiner
Humanized NOD/LtSz-scid IL2 receptor common gamma chain knockout mice in diabetes research., L D. Shultz, T Pearson, M King, L Giassi, L Carney, B Gott, B Lyons, A A. Rossini, and D L. Greiner
Effects of parathyroid hormone (1-34) on tibia in an adult rat model for chronic alcohol abuse., J D. Sibonga, U T. Iwaniec, K L. Shogren, C J. Rosen, and R T. Turner
Substance P as an immunomodulatory neuropeptide in a mouse model for autoimmune hair loss (alopecia areata)., F Siebenhaar, A A. Sharov, E M. Peters, T Y. Sharova, W Syska, A N. Mardaryev, Paul P. Freyschmidt, J P. Sundberg, M Maurer, and V A. Botchkarev
Invasion of the killer B's in type 1 diabetes., P A. Silveira, D V. Serreze, and S T. Grey
Effect of metformin and rosiglitazone in a prepubertal boy with Alstrom syndrome., S K. Sinha, A Bhangoo, H Anhalt, N Maclaren, J D. Marshall, G B. Collin, J K. Naggert, and S Ten
The mouse Gene Expression Database (GXD): 2007 update., C M. Smith, J H. Finger, T F. Hayamizu, I J. McCright, J T. Eppig, J A. Kadin, J E. Richardson, and M Ringwald
Eye research., R S. Smith, P M. Nishina, J P. Sundberg, J Zwaan, and S W. John
A standardized nomenclature for the mouse and rat prolactin superfamilies., M J. Soares, S M. Alam, M L. Duckworth, N D. Horseman, T Konno, D I. Linzer, L J. Maltais, Hamilton M. Nilsen, K Shiota, J R. Smith, and M Wallis
Distal renal tubular acidosis in mice lacking the AE1 (band3) Cl-/HCO3- exchanger (slc4a1)., P A. Stehberger, B E. Shmukler, Tilley A. Stuart, L L. Peters, S L. Alper, and C A. Wagner