Submissions from 2006
Relationship between insulin-like growth factor I, dehydroepiandrosterone sulfate and proresorptive cytokines and bone density in cystic fibrosis., C M. Gordon, E Binello, M S. LeBoff, M E. Wohl, C J. Rosen, and A A. Colin
Role of COL4A1 in small-vessel disease and hemorrhagic stroke., D B. Gould, F C. Phalan, M i. van, J P. Sundberg, K Vahedi, P Massin, M G. Bousser, P Heutink, J H. Miner, Lasserve E. Tournier, and S W. John
Mutant myocilin nonsecretion in vivo is not sufficient to cause glaucoma., D B. Gould, M Reedy, L A. Wilson, R S. Smith, R L. Johnson, and S W. John
Patterns and mechanisms of genome organization in the mouse., J H. Graber, G A. Churchill, K J. Dipetrillo, B L. King, P M. Petkov, and K Paigen
TEX14 is essential for intercellular bridges and fertility in male mice., M P. Greenbaum, W Yan, M H. Wu, Y N. Lin, J E. Agno, M Sharma, R E. Braun, A Rajkovic, and M M. Matzuk
The long and short of it: somite formation in mice., T Gridley
Validation of high-throughput methods for measuring blood urea nitrogen and urinary albumin concentrations in mice., S Grindle, C Garganta, S Sheehan, J Gile, A Lapierre, H Whitmore, B Paigen, and K DiPetrillo
Expression and localization of PCSK9 in rat hepatic cells., P N. Grozdanov, P M. Petkov, L K. Karagyozov, and M D. Dabeva
Effects of FXR in foam-cell formation and atherosclerosis development., G L. Guo, Fojo S. Santamarina, T E. Akiyama, M J. Amar, B J. Paigen, B Brewer, and F J. Gonzalez
A mouse TRAPP-related protein is involved in pigmentation., B Gwynn, R S. Smith, L B. Rowe, B A. Taylor, and L L. Peters
Mice deficient in the Rab5 guanine nucleotide exchange factor ALS2/alsin exhibit age-dependent neurological deficits and altered endosome trafficking., S Hadano, S C. Benn, S Kakuta, A Otomo, K Sudo, R Kunita, Utsunomiya K. Suzuki, H Mizumura, J M. Shefner, G A. Cox, Y Iwakura, R H. Brown, and J E. Ikeda
The transcription factor Nr2e3 functions in retinal progenitors to suppress cone cell generation., N B. Haider, P Demarco, A M. Nystuen, X Huang, R S. Smith, M A. McCall, J K. Naggert, and Patsy M. Nishina
Resistance of C57BL/6 mice to amoebiasis is mediated by nonhemopoietic cells but requires hemopoietic IL-10 production., S Hamano, A Asgharpour, S E. Stroup, T A. Wynn, E H. Leiter, and E Houpt
Mutagenesis as an unbiased approach to identify novel contraceptive targets., M A. Handel, C Lessard, L Reinholdt, J Schimenti, and J J. Eppig
Postnatal growth and bone mass in mice with IGF-I haploinsufficiency., J He, C J. Rosen, D J. Adams, and B E. Kream
Where do we stand now? Mouse early embryo patterning meeting in Freiburg, Germany (2005)., T Hiiragi, V B. Alarcon, T Fujimori, Vallee S. Louvet, M Maleszewski, Y Marikawa, B Maro, and D Solter
Embryology: does prepatterning occur in the mouse egg?, T Hiiragi, Vallee S. Louvet, D Solter, and B Maro
Fatal flaws in the case for prepatterning in the mouse egg., T Hiiragi and D Solter
Expression of chitinase-like proteins in the skin of chronic proliferative dermatitis (cpdm/cpdm) mice., H HogenEsch, A Dunham, R Seymour, M Renninger, and J P. Sundberg
Variation in genes involved in the RANKL/RANK/OPG bone remodeling pathway are associated with bone mineral density at different skeletal sites in men., Y H. Hsu, T Niu, H A. Terwedow, X Xu, Y Feng, Z Li, J D. Brain, C J. Rosen, N Laird, and X Xu
Impaired bone anabolic response to parathyroid hormone in Fgf2-/- and Fgf2+/- mice., M M. Hurley, Y Okada, L Xiao, Y Tanaka, M Ito, N Okimoto, T Nakamura, C J. Rosen, T Doetschman, and J D. Coffin
A scalable method for integration and functional analysis of multiple microarray datasets., C Huttenhower, M Hibbs, C Myers, and O G. Troyanskaya
Targeting multiple kinase pathways in leukemic progenitors and stem cells is essential for improved treatment of Ph+ leukemia in mice., Y Hu, S Swerdlow, T M. Duffy, R Weinmann, F Y. Lee, and S Li
Adult mice lacking the p53/p63 target gene Perp are not predisposed to spontaneous tumorigenesis but display features of ectodermal dysplasia syndromes., R A. Ihrie, R T. Bronson, and L D. Attardi
Role of hepatocyte nuclear factor 4alpha in control of blood coagulation factor gene expression., Y Inoue, L L. Peters, S H. Yim, J Inoue, and F J. Gonzalez
Purified human hematopoietic stem cells contribute to the generation of cardiomyocytes through cell fusion., F Ishikawa, H Shimazu, L D. Shultz, M Fukata, R Nakamura, B Lyons, K Shimoda, S Shimoda, T Kanemaru, K Nakamura, H Ito, Y Kaji, A C. Perry, and M Harada
Quantitative Trait Loci That Determine BMD in C57BL/6J and 129S1/SvImJ Inbred Mice., N Ishimori, R Li, K A. Walsh, R Korstanje, J A. Rollins, P Petkov, M T. Pletcher, T Wiltshire, L R. Donahue, C J. Rosen, W G. Beamer, G A. Churchill, and B Paigen
Transgenic mice with osteoblast-targeted insulin-like growth factor-I show increased bone remodeling., J Jiang, A C. Lichtler, G A. Gronowicz, D J. Adams, S H. Clark, C J. Rosen, and B E. Kream
K-ras activation generates an inflammatory response in lung tumors., H Ji, A M. Houghton, T J. Mariani, S Perera, C B. Kim, R Padera, G Tonon, K McNamara, L A. Marconcini, A Hezel, Bardeesy N. El, R T. Bronson, D Sugarbaker, R S. Maser, S D. Shapiro, and K K. Wong
The impact of human EGFR kinase domain mutations on lung tumorigenesis and in vivo sensitivity to EGFR-targeted therapies., H Ji, D Li, L Chen, A Mitchell, L R. Chirieac, R T. Bronson, W Kim, P A. Janne, R Weissleder, and et al
Epidermal growth factor receptor variant III mutations in lung tumorigenesis and sensitivity to tyrosine kinase inhibitors., H Ji, X Zhao, Y Yuza, T Shimamura, D Li, Y Sun, Hashem R. Al, R T. Bronson, S K. Rabindran, C M. Discafani, and al et
Special issue: mouse models for hearing research., K R. Johnson
Strain background effects and genetic modifiers of hearing in mice., K R. Johnson, Q Y. Zheng, and Trauth K. Noben
A comparison of vestibular and auditory phenotypes in inbred mouse strains., S M. Jones, T A. Jones, K R. Johnson, H Yu, L C. Erway, and Q Y. Zheng
ABCA1 overexpression in the liver of LDLr-KO mice leads to accumulation of pro-atherogenic lipoproteins and enhanced atherosclerosis., C W. Joyce, E M. Wagner, F Basso, M J. Amar, L A. Freeman, R D. Shamburek, C L. Knapper, J Syed, J Wu, B L. Vaisman, Najib J. Fruchart, E M. Billings, B Paigen, A T. Remaley, Fojo S. Santamarina, and H B. Brewer
Severe epilepsy resulting from genetic interaction between Scn2a and Kcnq2., J A. Kearney, Y Yang, B Beyer, S K. Bergren, L Claes, P Dejonghe, and W N. Frankel
Natural variation and genetic covariance in adult hippocampal neurogenesis., G Kempermann, E J. Chesler, L Lu, R W. Williams, and F H. Gage
The Notch ligand JAG1 is required for sensory progenitor development in the mammalian inner ear., A E. Kiernan, J Xu, and T Gridley
Albumin turnover: FcRn-mediated recycling saves as much albumin from degradation as the liver produces., J Kim, C L. Bronson, W L. Hayton, M D. Radmacher, D C. Roopenian, J M. Robinson, and C L. Anderson
Phenotypic characterization of polygenic type 2 diabetes in TALLYHO/JngJ mice., J H. Kim, T P. Stewart, Bejnood M. Soltani, L Wang, J M. Fortuna, O A. Mostafa, Moussa N. Moustaid, A M. Shoieb, M F. McEntee, Y Wang, L Bechtel, and J K. Naggert
Inactivation of conditional Rb by Villin-Cre leads to aggressive tumors outside the gastrointestinal tract., M H. Kucherlapati, A A. Nguyen, R T. Bronson, and R S. Kucherlapati
Adenomatous polyposis coli (APC) is required for normal development of skin and thymus., M Kuraguchi, X P. Wang, R T. Bronson, R Rothenberg, Baah N. Ohene, J J. Lund, M Kucherlapati, R L. Maas, and R Kucherlapati
The diabetes-prone NZO/Hl strain. Proliferation capacity of beta cells in hyperinsulinemia and hyperglycemia., C Lange, K Jeruschke, L Herberg, E H. Leiter, and E Junger
Novel leptin receptor mutation in NOD/LtJ mice suppresses type 1 diabetes progression: II. Immunologic analysis., C H. Lee, Y G. Chen, J Chen, P C. Reifsnyder, D V. Serreze, Salzler M. Clare, M Rodriguez, C Wasserfall, M A. Atkinson, and E H. Leiter
Editing-defective tRNA synthetase causes protein misfolding and neurodegeneration., J W. Lee, K Beebe, L A. Nangle, J Jang, Guess C. Longo, S A. Cook, M T. Davisson, J P. Sundberg, P Schimmel, and S L. Ackerman
Differential endocrine responses to rosiglitazone therapy in new mouse models of type 2 diabetes., E H. Leiter, P C. Reifsnyder, W Zhang, H J. Pan, Q Xiao, and J Mistry
Attenuation of murine lysosomal storage disease by allogeneic neonatal bone marrow transplantation using costimulatory blockade and donor lymphocyte infusion without myeloablation., M D. Lessard, T L. Alley, J L. Proctor, B Levy, N Galvin, C A. Vogler, and B W. Soper
Integrative genetic analysis of transcription modules: towards filling the gap between genetic loci and inherited traits., H Li, H Chen, L Bao, K F. Manly, E J. Chesler, L Lu, J Wang, M Zhou, R W. Williams, and Y Cui
Increased susceptibility to UV-induced skin carcinogenesis in polymerase eta-deficient mice., Q Lin, A B. Clark, S D. McCulloch, T Yuan, R T. Bronson, T A. Kunkel, and R Kucherlapati
Structural model analysis of multiple quantitative traits., R Li, S W. Tsaih, K Shockley, I M. Stylianou, J Wergedal, B Paigen, and G A. Churchill
Quantitative comparison of EST libraries requires compensation for systematic biases in cDNA generation., D Liu and J H. Graber
Generation and characterization of a novel tetravalent anti-CD22 antibody with improved antitumor activity and pharmacokinetics., X Y. Liu, L M. Pop, D C. Roopenian, V Ghetie, E S. Vitetta, and J E. Smallshaw
Epithelial-specific and stage-specific functions of insulin-like growth factor-I during postnatal mammary development., A V. Loladze, M A. Stull, A M. Rowzee, J Demarco, J H. Lantry, C J. Rosen, D Leroith, K U. Wagner, L Hennighausen, and T L. Wood
Deficiency of SHP-1 protein-tyrosine phosphatase in "viable motheaten" mice results in retinal degeneration., B L. Lyons, R S. Smith, R E. Hurd, N L. Hawes, L M. Burzenski, S Nusinowitz, M G. Hasham, B Chang, and L D. Shultz
Gradual elimination of retroviruses in YBR/Ei mice., C C. MacDearmid, L K. Case, C L. Starling, and T V. Golovkina
Transcript annotation in FANTOM3: mouse gene catalog based on physical cDNAs., N Maeda, T Kasukawa, R Oyama, C J. Bult, D Hill, J Quackenbush, K Sugiura, Y Zhu, and al et
A novel somatic mouse model to survey tumorigenic potential applied to the Hedgehog pathway., J Mao, K L. Ligon, E Y. Rakhlin, S P. Thayer, R T. Bronson, D Rowitch, and A P. McMahon
Anti-mouse CD154 antibody treatment facilitates generation of mixed xenogeneic rat hematopoietic chimerism, prevents wasting disease and prolongs xenograft survival in mice., H Masaki, M C. Appel, L Leahy, J Leif, L Paquin, L D. Shultz, J P. Mordes, D L. Greiner, and A A. Rossini
Loss of notch activity in the developing central nervous system leads to increased cell death., H A. Mason, S M. Rakowiecki, T Gridley, and G Fishell
Spermatocyte responses in vitro to induced DNA damage., S Matulis and M A. Handel
Intestinal-specific PPARgamma deficiency enhances tumorigenesis in ApcMin/+ mice., C A. McAlpine, Y Barak, I Matise, and R T. Cormier
Generation of new Notch2 mutant alleles., B McCright, J Lozier, and T Gridley
4Pi microscopy of quantum dot-labeled cellular structures., R Medda, S Jakobs, S W. Hell, and J Bewersdorf
Expression of terminal differentiation proteins defines stages of mouse mammary gland development., I Mikaelian, M Hovick, K A. Silva, L M. Burzenski, L D. Shultz, Bicknell C. Ackert, G A. Cox, and J P. Sundberg
Genomic instability and aging-like phenotype in the absence of mammalian SIRT6., R Mostoslavsky, K F. Chua, D B. Lombard, W W. Pang, M R. Fischer, L Gellon, P Liu, N Nunez, R Bronson, D Frendewey, and al et
Space asymmetry directs preferential sperm entry in the absence of polarity in the mouse oocyte., N Motosugi, J E. Dietrich, Z Polanski, D Solter, and T Hiiragi
Effects of GH and/or sex steroids on circulating IGF-I and IGFBPs in healthy, aged women and men., T Munzer, C J. Rosen, S M. Harman, K M. Pabst, Clair C. St, J D. Sorkin, and M R. Blackman
Generation of a Snail1 (Snai1) conditional null allele., S A. Murray, E A. Carver, and T Gridley
Snail1 gene function during early embryo patterning in mice., S A. Murray and T Gridley
Snail family genes are required for left-right asymmetry determination, but not neural crest formation, in mice., S A. Murray and T Gridley
Finding function: evaluation methods for functional genomic data., C L. Myers, D R. Barrett, M A. Hibbs, C Huttenhower, and O G. Troyanskaya
Early immunization induces persistent tumor-infiltrating CD8+ T cells against an immunodominant epitope and promotes lifelong control of pancreatic tumor progression in SV40 tumor antigen transgenic mice., P Otahal, T D. Schell, S C. Hutchinson, B B. Knowles, and S S. Tevethia
A spontaneous mutation involving Kcnq2 (Kv7.2) reduces M-current density and spike frequency adaptation in mouse CA1 neurons., J F. Otto, Y Yang, W N. Frankel, H S. White, and K S. Wilcox
An siRNA-based microbicide protects mice from lethal herpes simplex virus 2 infection., D Palliser, D Chowdhury, Q Y. Wang, S J. Lee, R T. Bronson, D M. Knipe, and J Lieberman
A polymorphism in New Zealand inbred mouse strains that inactivates phosphatidylcholine transfer protein., H J. Pan, D S. Agate, B L. King, M K. Wu, S L. Roderick, E H. Leiter, and D E. Cohen
Adverse hepatic and cardiac responses to rosiglitazone in a new mouse model of type 2 diabetes: relation to dysregulated phosphatidylcholine metabolism., H J. Pan, Y Lin, Y E. Chen, D E. Vance, and E H. Leiter
Ribosomal protein S6 gene haploinsufficiency is associated with activation of a p53-dependent checkpoint during gastrulation., L Panic, S Tamarut, Jantscheff M. Sticker, M Barkic, D Solter, M Uzelac, K Grabusic, and S Volarevic
Glial cell line-derived neurotrophic factor maintains a POZ-itive influence on stem cells., C Payne and R E. Braun
Histone lysine trimethylation exhibits a distinct perinuclear distribution in Plzf-expressing spermatogonia., C Payne and R E. Braun
Epigenetics and phenotypic variation in mammals., A E. Peaston and E Whitelaw
The fibrinolytic system facilitates tumor cell migration across the blood-brain barrier in experimental melanoma brain metastasis., G Perides, Y Zhuge, T Lin, M F. Stins, R T. Bronson, and J K. Wu
Quantitative trait loci for baseline erythroid traits., L L. Peters, A J. Lambert, W Zhang, G A. Churchill, C Brugnara, and O S. Platt
Enhanced half-life of genetically engineered human IgG1 antibodies in a humanized FcRn mouse model: potential application in humorally mediated autoimmune disease., S B. Petkova, S Akilesh, T J. Sproule, G J. Christianson, Khabbaz H. Al, A C. Brown, L G. Presta, Y G. Meng, and D C. Roopenian
Human antibodies induce arthritis in mice deficient in the low-affinity inhibitory IgG receptor Fc gamma RIIB., S B. Petkova, K N. Konstantinov, T J. Sproule, B L. Lyons, M A. Awwami, and D C. Roopenian
Evidence that the satin hair mutant gene Foxq1 is among multiple and functionally diverse regulatory targets for Hoxc13 during hair follicle differentiation., C S. Potter, R L. Peterson, J L. Barth, N D. Pruett, D F. Jacobs, M J. Kern, W S. Argraves, J P. Sundberg, and A Awgulewitsch
Pituitary removal in adult mice increases life span., R W. Powers, D E. Harrison, and K Flurkey
TRPV1+ sensory neurons control beta cell stress and islet inflammation in autoimmune diabetes., R Razavi, Y Chan, F N. Afifiyan, X J. Liu, X Wan, J Yantha, H Tsui, L Tang, S Tsai, P Santamaria, J P. Driver, D Serreze, M W. Salter, and H M. Dosch
An imprinted locus epistatically influences Nstr1 and Nstr2 to control resistance to nerve sheath tumors in a neurofibromatosis type 1 mouse model., K M. Reilly, K W. Broman, R T. Bronson, S Tsang, D A. Loisel, E S. Christy, Z Sun, J Diehl, D J. Munroe, and R G. Tuskan
The mouse gcd2 mutation causes primordial germ cell depletion., L G. Reinholdt, R J. Munroe, S Kamdar, and J C. Schimenti
fjoin: simple and efficient computation of feature overlaps., J E. Richardson
Effect of complete protein 4.1R deficiency on ion transport properties of murine erythrocytes., A Rivera, Franceschi L. De, L L. Peters, P Gascard, N Mohandas, and C Brugnara
Dlx5 and Dlx6 homeobox genes are required for specification of the mammalian vestibular apparatus., R F. Robledo and T Lufkin
Managing success: mutant mouse repositories., Rockwood SF, Fray MD, Nakagata N
In search of new targets for plasma high-density lipoprotein cholesterol levels: promise of human-mouse comparative genomics., J Rollins, Y Chen, B Paigen, and X Wang
Mechanisms of disease: is osteoporosis the obesity of bone?, C J. Rosen and M L. Bouxsein
IGF-I secretion by prostate carcinoma cells does not alter tumor-bone cell interactions in vitro or in vivo., J Rubin, X Fan, J Rahnert, B Sen, C L. Hsieh, T C. Murphy, M S. Nanes, L G. Horton, W G. Beamer, and C J. Rosen
Grey, a novel mutation in the murine Lyst gene, causes the beige phenotype by skipping of exon 25., F Runkel, H Bussow, K L. Seburn, G A. Cox, D M. Ward, J Kaplan, and T Franz
A multispecies comparison of the metazoan 3'-processing downstream elements and the CstF-64 RNA recognition motif., J Salisbury, K W. Hutchison, and J H. Graber
The pleiotropic function of PPARgamma in the placenta., W T. Schaiff, Y Barak, and Y Sadovsky
Computational pathology: challenges in the informatics of phenotype description in mutant mice., Schofield PN, Bard JBL, Rozell B, Sundberg JP