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Submissions from 2007

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The classical complement cascade mediates CNS synapse elimination., B Stevens, N J. Allen, L E. Vazquez, G R. Howell, K S. Christopherson, N Nouri, K D. Micheva, A K. Mehalow, A D. Huberman, B Stafford, A Sher, A M. Litke, J D. Lambris, S J. Smith, S W. John, and B A. Barres

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Elimination of antigen-presenting cells and autoreactive T cells by Fas contributes to prevention of autoimmunity., P B. Stranges, J Watson, C J. Cooper, Rossi C. Choisy, A C. Stonebraker, R A. Beighton, H Hartig, J P. Sundberg, S Servick, G Kaufmann, P J. Fink, and A V. Chervonsky

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Oocyte-derived BMP15 and FGFs cooperate to promote glycolysis in cumulus cells., K Sugiura, Y Q. Su, F J. Diaz, S A. Pangas, S Sharma, K Wigglesworth, M J. O'Brien, M M. Matzuk, S Shimasaki, and J J. Eppig

Training mouse pathologists: five years of pathology of mouse models of human disease workshops., J P. Sundberg, R C. Hackman, H HogenEsch, A Y. Nikitin, and J M. Ward

Failure to induce alopecia areata in C3H/HeJ mice with exogenous interferon gamma., J P. Sundberg, K A. Silva, K Edwards, S Black, A B. Jenson, and L E. King

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Selective degradation of transcripts during meiotic maturation of mouse oocytes., Y Q. Su, K Sugiura, Y Woo, K Wigglesworth, S Kamdar, J Affourtit, and J J. Eppig

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Multiple trait measurements in 43 inbred mouse strains capture the phenotypic diversity characteristic of human populations., K L. Svenson, Smith R. Von, P A. Magnani, H R. Suetin, B Paigen, J K. Naggert, R Li, G A. Churchill, and L L. Peters

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Effects of loss of classical estrogen response element signaling on bone in male mice., Syed FA Fraser DG Spelsberg TC Rosen CJ Krust A Chambon P Jameson JL Khosia S

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Effects of loss of classical estrogen response element signaling on bone in male mice., F A. Syed, D G. Fraser, T C. Spelsberg, C J. Rosen, A Krust, P Chambon, J L. Jameson, and S Khosla

Critical role of endothelial Notch1 signaling in postnatal angiogenesis., K Takeshita, M Satoh, M Ii, M Silver, F P. Limbourg, Y Mukai, Y Rikitake, F Radtke, T Gridley, D W. Losordo, and J K. Liao

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Characterization of human embryonic stem cell lines by the International Stem Cell Initiative., The International Stem Cell Initiative, O Adewumi, G A. Churchill, B L. King, B B. Knowles, and et al

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Type 1 IFN mediates cross-talk between innate and adaptive immunity that abrogates transplantation tolerance., T B. Thornley, N E. Phillips, Zlatanova B. Beaudette, T G. Markees, K Bahl, M A. Brehm, L D. Shultz, Jones E. Kurt, J P. Mordes, R M. Welsh, A A. Rossini, and D L. Greiner

Human clonal CD8 autoreactivity to an IGRP islet epitope shared between mice and men., W W. Unger, G G. Pinkse, van der Kracht Mulder, der Slik A. van, M G. Kester, F Ossendorp, J W. Drijfhout, D V. Serreze, and B O. Roep

Over 60% of NIH extramural funding involves animal-related research., T Valli, S W. Barthold, J E. Ward, C Brayton, A Nikitin, A D. Borowsky, R T. Bronson, R D. Cardiff, J Sundberg, and T Ince

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Complete genomic characterization of a murine papillomavirus isolated from papillomatous lesions of a European harvest mouse (Micromys minutus)., Doorslaer K. Van, A Rector, A B. Jenson, J P. Sundberg, Ranst M. Van, and S J. Ghim

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Ovalbumin serves as a neo-transplantation antigen in retinal pigment epithelial cells., J R. Wajchman, J C. Zimring, J P. Lake, J Wen, and J A. Kapp

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Mutation in mouse hei10, an e3 ubiquitin ligase, disrupts meiotic crossing over., J O. Ward, L G. Reinholdt, W W. Motley, L M. Niswander, D C. Deacon, L B. Griffin, K K. Langlais, V L. Backus, K J. Schimenti, M J. O'Brien, J J. Eppig, and J C. Schimenti

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Mapping genetic loci that regulate lipid levels in a NZB/B1NJxRF/J intercross and a combined intercross involving NZB/B1NJ, RF/J, MRL/MpJ, and SJL/J mouse strains., J E. Wergedal, Bicknell C. Ackert, W G. Beamer, S Mohan, D J. Baylink, and A K. Srivastava

Factors affecting hearing in mice, rats, and other laboratory animals., J F. Willott

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Diminished lifespan and acute stress-induced death in DNA-PKcs-deficient mice with limiting telomeres., K K. Wong, R S. Maser, E Sahin, S T. Bailey, H Xia, H Ji, K McNamara, M Naylor, R T. Bronson, S Ghosh, R Welsh, and R A. DePinho

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Protein 4.1B suppresses prostate cancer progression and metastasis., S Y. Wong, H Haack, J L. Kissil, M Barry, R T. Bronson, S S. Shen, C A. Whittaker, D Crowley, and R O. Hynes

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The nonhomologous end joining factor Artemis suppresses multi-tissue tumor formation and prevents loss of heterozygosity., Y Woo, S M. Wright, S A. Maas, T L. Alley, L B. Caddle, S Kamdar, J Affourtit, O Foreman, E C. Akeson, D Shaffer, R T. Bronson, H C. Morse, D Roopenian, and K D. Mills

Assessing human germ-cell mutagenesis in the Postgenome Era: a celebration of the legacy of William Lawson (Bill) Russell., A J. Wyrobek, J J. Mulvihill, J S. Wassom, H V. Malling, M D. Shelby, S E. Lewis, K L. Witt, R J. Preston, S D. Perreault, J W. Allen, D M. Demarini, R P. Woychik, and J B. Bishop

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Interleukin-2 gene variation impairs regulatory T cell function and causes autoimmunity., J Yamanouchi, D Rainbow, P Serra, S Howlett, K Hunter, V E. Garner, Munoz A. Gonzalez, J Clark, R Veijola, R Cubbon, S L. Chen, R Rosa, A M. Cumiskey, D V. Serreze, S Gregory, al et, and P Santamaria

Different mechanisms control peripheral and central tolerance in hematopoietic chimeric mice., M Yamazaki, T Pearson, M A. Brehm, D M. Miller, J A. Mangada, T G. Markees, L D. Shultz, J P. Mordes, A A. Rossini, and D L. Greiner

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On the subspecific origin of the laboratory mouse., H Yang, T A. Bell, G A. Churchill, and Manuel de Pardo

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Estimating p-values in small microarray experiments., H Yang and G Churchill

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Complex seizure disorder caused by Brunol4 deficiency in mice., Y Yang, C L. Mahaffey, N Berube, T P. Maddatu, G A. Cox, and W N. Frankel

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Effects of carbonic anhydrase VIII deficiency on cerebellar gene expression profiles in the wdl mouse., J Yan, Y Jiao, F Jiao, J Stuart, L R. Donahue, W G. Beamer, X Li, B A. Roe, M S. LeDoux, and W Gu

Evaluation of gene expression profiling in a mouse model of L-gulonolactone oxidase gene deficiency., J Yan, Y Jiao, X Li, F Jiao, W G. Beamer, C J. Rosen, and W Gu

Detecting novel bone density and bone size quantitative trait loci using a cross of MRL/MpJ and CAST/EiJ inbred mice., H Yu, S Mohan, B Edderkaoui, G L. Masinde, H M. Davidson, J E. Wergedal, W G. Beamer, and D J. Baylink

Cancer stem cells., Kyuson Yun and Barbara Tennent

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Impact of seafood and fruit consumption on bone mineral density., P A. Zalloua, Y H. Hsu, H Terwedow, T Zang, D Wu, G Tang, Z Li, X Hong, S T. Azar, B Wang, M L. Bouxsein, J Brain, S R. Cummings, C J. Rosen, and X Xu

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Evidence that MIG-6 is a tumor-suppressor gene., Y W. Zhang, B Staal, Y Su, P Swiatek, P Zhao, B Cao, J Resau, R Sigler, R Bronson, and Woude G. Vande

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Utp14b: A unique retrogene within a gene that has acquired multiple promoters and a specific function in spermatogenesis., M Zhao, J Rohozinski, M Sharma, J Ju, R E. Braun, C E. Bishop, and M L. Meistrich

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Tympanometry assessment of 61 inbred strains of mice., Q Y. Zheng, Y C. Tong, K N. Alagramam, and H Yu

Submissions from 2006

Genetically Engineered Mice Handbook

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Treatment and transfer of emphysema by a new bone marrow transplantation method from normal mice to Tsk mice and vice versa., Y Adachi, H Oyaizu, S Taketani, K Minamino, K Yamaguchi, L D. Shultz, M Iwasaki, M Tomita, Y Suzuki, K Nakano, Y Koike, R Yasumizu, M Sata, N Hirama, I Kubota, S Fukuhara, and S Ikehara

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Targeting PIM kinases impairs survival of hematopoietic cells transformed by kinase inhibitor-sensitive and kinase inhibitor-resistant forms of Fms-like tyrosine kinase 3 and BCR/ABL., M Adam, V Pogacic, M Bendit, R Chappuis, M C. Nawijn, J Duyster, C J. Fox, C B. Thompson, J Cools, and J Schwaller

Genetic increase in serum insulin-like growth factor-I (IGF-I) in C3H/HeJ compared with C57BL/6J mice is associated with increased transcription from the IGF-I exon 2 promoter., M L. Adamo, X Ma, Bicknell C. Ackert, L R. Donahue, W G. Beamer, and C J. Rosen

Chromosomal inversion discovered in C3H/HeJ mice., E C. Akeson, L R. Donahue, W G. Beamer, K L. Shultz, Bicknell C. Ackert, C J. Rosen, J Corrigan, and M T. Davisson

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Scanning transmission X-ray microscopic analysis of purified melanosomes of the mouse iris., M G. Anderson, T Haraszti, G E. Petersen, S Wirick, C Jacobsen, S W. John, and M Grunze

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Genetic context determines susceptibility to intraocular pressure elevation in a mouse pigmentary glaucoma., M G. Anderson, R T. Libby, M Mao, I M. Cosma, L A. Wilson, R S. Smith, and S W. John

Developmental remodelling of the lemniscal synapse in the ventral basal thalamus of the mouse., D Arsenault and Z W. Zhang

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Enhanced ABCG1 expression increases atherosclerosis in LDLr-KO mice on a western diet., F Basso, M J. Amar, E M. Wagner, B Vaisman, B Paigen, Fojo S. Santamarina, and A T. Remaley

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Short-term changes in bone turnover markers and bone mineral density response to parathyroid hormone in postmenopausal women with osteoporosis., D C. Bauer, P Garnero, J P. Bilezikian, S L. Greenspan, K E. Ensrud, C J. Rosen, L Palermo, and D M. Black

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Test- and behavior-specific genetic factors affect WKY hypoactivity in tests of emotionality., A E. Baum, L C. Solberg, G A. Churchill, N Ahmadiyeh, J S. Takahashi, and E E. Redei

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MyD88 deficiency results in tissue-specific changes in cytokine induction and inflammation in interleukin-18-independent mice infected with Borrelia burgdorferi., A K. Behera, E Hildebrand, R T. Bronson, G Perides, S Uematsu, S Akira, and L T. Hu

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H2AX chromatin structures and their response to DNA damage revealed by 4Pi microscopy., J Bewersdorf, B T. Bennett, and K L. Knight

Development and progression of alopecia in the vitamin D receptor null mouse., D D. Bikle, H Elalieh, S Chang, Z Xie, and J P. Sundberg

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The Mouse Genome Database (MGD): updates and enhancements., J A. Blake, J T. Eppig, C J. Bult, J A. Kadin, and J E. Richardson

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Beyond the data deluge: data integration and bio-ontologies., Judith A. Blake and Carol J Bult

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In vivo magnetic resonance imaging and semiautomated image analysis extend the brain phenotype for cdf/cdf mice., N A. Bock, N Kovacevic, T V. Lipina, J C. Roder, S L. Ackerman, and R M. Henkelman

Safety and efficacy of teriparatide in elderly women with established osteoporosis: bone anabolic therapy from a geriatric perspective., S Boonen, F Marin, D Mellstrom, L Xie, D Desaiah, J H. Krege, and C J. Rosen

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Targeted disruption of tyrosylprotein sulfotransferase-2, an enzyme that catalyzes post-translational protein tyrosine O-sulfation, causes male infertility., A Borghei, Y B. Ouyang, A D. Westmuckett, M R. Marcello, C P. Landel, J P. Evans, and K L. Moore

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Novel mutations in three families confirm a major role of COL4A1 in hereditary porencephaly., G Breedveld, Coo I. de, M H. Lequin, W F. Arts, P Heutink, D B. Gould, S W. John, B Oostra, and G M. Mancini

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The X chromosome in quantitative trait locus mapping., K W. Broman, S Sen, S E. Owens, A Manichaikul, Smith E. Southard, and G A. Churchill

Pooling and PCR as a method to combat low frequency gene targeting in mouse embryonic stem cells., A C. Brown, C P. Lerner, J H. Graber, D J. Shaffer, and D C. Roopenian

From vivarium to bedside: lessons learned from animal models., E Budzynski, Y Lee, K Sakamoto, J K. Naggert, and P M. Nishina

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From information to understanding: the role of model organism databases in comparative and functional genomics., C J. Bult

The mouse tumour biology database: an online resource for mouse models of human cancer., C J. Bult, D M. Krupke, M M. Vincent, T Allio, J P. Sundberg, I Mikaelian, and J T. Eppig

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Motor axon guidance of the mammalian trochlear and phrenic nerves: dependence on the netrin receptor Unc5c and modifier loci., R W. Burgess, T J. Jucius, and S L. Ackerman

Performance of ten inbred mouse strains following assisted reproductive technologies (ARTs)., S L. Byers, S J. Payson, and R A. Taft

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Cochlear developmental defect and background-dependent hearing thresholds in the Jackson circler (jc) mutant mouse., A Calderon, A Derr, B B. Stagner, K R. Johnson, G Martin, and Trauth K. Noben

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Disentangling information flow in the Ras-cAMP signaling network., G W. Carter, S Rupp, G R. Fink, and T Galitski

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Jag2-Notch1 signaling regulates oral epithelial differentiation and palate development., L M. Casey, Y Lan, E S. Cho, K M. Maltby, T Gridley, and R Jiang

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Cone photoreceptor function loss-3, a novel mouse model of achromatopsia due to a mutation in Gnat2., B Chang, M S. Dacey, N L. Hawes, P F. Hitchcock, A H. Milam, Sonmez P. Atmaca, S Nusinowitz, and J R. Heckenlively

The nob2 mouse, a null mutation in Cacna1f: anatomical and functional abnormalities in the outer retina and their consequences on ganglion cell visual responses., B Chang, J R. Heckenlively, P R. Bayley, N C. Brecha, M T. Davisson, N L. Hawes, A A. Hirano, R E. Hurd, A Ikeda, B A. Johnson, M A. McCall, C W. Morgans, S Nusinowitz, N S. Peachey, D S. Rice, K A. Vessey, and R G. Gregg

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In-frame deletion in a novel centrosomal/ciliary protein CEP290/NPHP6 perturbs its interaction with RPGR and results in early-onset retinal degeneration in the rd16 mouse., B Chang, H Khanna, N Hawes, D Jimeno, S He, C Lillo, S K. Parapuram, H Cheng, A Scott, R E. Hurd, J A. Sayer, E A. Otto, J R. Heckenlively, and al et

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Targeted disruption of CD38 accelerates autoimmune diabetes in NOD/Lt mice by enhancing autoimmunity in an ADP-ribosyltransferase 2-dependent fashion., J Chen, Y G. Chen, P C. Reifsnyder, W H. Schott, C H. Lee, M Osborne, F Scheuplein, F Haag, Nolte F. Koch, D V. Serreze, and E H. Leiter

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CD38 is required for the peripheral survival of immunotolerogenic CD4+ invariant NK T cells in nonobese diabetic mice., Y G. Chen, J Chen, M A. Osborne, H D. Chapman, G S. Besra, S A. Porcelli, E H. Leiter, S B. Wilson, and D V. Serreze

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The genetics of gene expression., G A. Churchill

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The MHC class I-related FcRn ameliorates murine Lyme arthritis., H Crowley, J Alroy, T J. Sproule, D Roopenian, and B T. Huber

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p25/cyclin-dependent kinase 5 induces production and intraneuronal accumulation of amyloid beta in vivo., J C. Cruz, D Kim, L Y. Moy, M M. Dobbin, X Sun, R T. Bronson, and L H. Tsai

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Inheritance patterns of transcript levels in F1 hybrid mice., X Cui, J Affourtit, K R. Shockley, Y Woo, and G A. Churchill

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FIMRe: Federation of International Mouse Resources: global networking of resource centers., M Davisson

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The benefits of strain donation., M Davisson and S Rockwood

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Strategies for managing an ever increasing mutant mouse repository., M T. Davisson and R A. Taft

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Congenic mice provide in vivo evidence for a genetic locus that modulates serum insulin-like growth factor-I and bone acquisition., K M. Delahunty, K L. Shultz, G A. Gronowicz, Jaremko B. Koczon, M L. Adamo, L G. Horton, J Lorenzo, L R. Donahue, Bicknell C. Ackert, B E. Kream, W G. Beamer, and C J. Rosen

Influence of caloric restriction on motor behavior, longevity, and brain lipid composition in Sandhoff disease mice., C A. Denny, J L. Kasperzyk, K N. Gorham, R T. Bronson, and T N. Seyfried

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Development of the Minimum Information Specification for In Situ Hybridization and Immunohistochemistry Experiments (MISFISHIE)., E W. Deutsch, C A. Ball, J Christiansen, D Davidson, M Korb, J C. Mills, A Oudes, H E. Parkinson, J Quackenbush, M Ringwald, S A. Sansone, Y Zhou, and A Y. Liu

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The preantral granulosa cell to cumulus cell transition in the mouse ovary: development of competence to undergo expansion., F J. Diaz, M J. O'Brien, K Wigglesworth, and J J. Eppig

Using ontology visualization to coordinate cross-species functional annotation for human disease genes., M E. Dolan and J A. Blake

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Genomes as geography: using GIS technology to build interactive genome feature maps., M E. Dolan, C C. Holden, M K. Beard, and C J. Bult

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A-to-I pre-mRNA editing of the serotonin 2C receptor: comparisons among inbred mouse strains., Y Du, M T. Davisson, K Kafadar, and K Gardiner

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Multiple genetic loci from CAST/EiJ chromosome 1 affect vBMD either positively or negatively in a C57BL/6J background., B Edderkaoui, D J. Baylink, W G. Beamer, J E. Wergedal, N R. Dunn, K L. Shultz, and S Mohan

Mouse models of efficient and inefficient anti-tumor immunity, with emphasis on minimal residual disease and tumor escape., I K. Egorov

Sharing research tools: the laboratory mouse., Einhorn D

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Cracking the egg: molecular dynamics and evolutionary aspects of the transition from the fully grown oocyte to embryo., A V. Evsikov, J H. Graber, J M. Brockman, A Hampl, A E. Holbrook, P Singh, J J. Eppig, D Solter, and B B. Knowles

Microbiological monitoring of laboratory mice., Fahey JR

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Identification of candidate alkylator-induced cancer susceptibility genes by whole genome scanning in mice., T S. Fenske, C McMahon, D Edwin, J C. Jarvis, J M. Cheverud, V Mathews, M A. Bogue, H L. McLeod, and T A. Graubert

Biological methods for archiving and maintaining mutant laboratory mice., Fray MD, Glenister PH, Rockwood S, Kaneko T, Nakagata N

Interferon-gamma-deficient mice are resistant to the development of alopecia areata., Paul P. Freyschmidt, K J. McElwee, R Hoffmann, J P. Sundberg, M Vitacolonna, S Kissling, and M Zoller

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Discrimination of Non-Protein-Coding Transcripts from Protein-Coding mRNA., M C. Frith, T L. Bailey, T Kasukawa, F Mignone, S K. Kummerfeld, M Madera, S Sunkara, M Furuno, C J. Bult, J Quackenbush, C Kai, J Kawai, P Carninci, Y Hayashizaki, G Pesole, and J S. Mattick

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Clusters of internally primed transcripts reveal novel long noncoding RNAs., M Furuno, K C. Pang, N Ninomiya, S Fukuda, M C. Frith, C Bult, C Kai, J Kawai, P Carninci, Y Hayashizaki, J S. Mattick, and H Suzuki

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The chloride intracellular channel protein CLIC5 is expressed at high levels in hair cell stereocilia and is essential for normal inner ear function., L H. Gagnon, Guess C. Longo, M Berryman, J B. Shin, K W. Saylor, H Yu, P G. Gillespie, and K R. Johnson

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Response rate of bone mineral density to teriparatide in postmenopausal women with osteoporosis., J C. Gallagher, C J. Rosen, P Chen, D A. Misurski, and R Marcus

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Trak1 mutation disrupts GABA(A) receptor homeostasis in hypertonic mice., S L. Gilbert, L Zhang, M L. Forster, J R. Anderson, T Iwase, B Soliven, L R. Donahue, H O. Sweet, R T. Bronson, M T. Davisson, R L. Wollmann, and B T. Lahn

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Progress in using mouse inbred strains, consomics, and mutants to identify genes related to stress, anxiety, and alcohol phenotypes., D Goldowitz, D B. Matthews, K M. Hamre, G Mittleman, E J. Chesler, H C. Becker, M F. Lopez, S R. Jones, T A. Mathews, M F. Miles, R Kerns, and K A. Grant

Mouse genome informatics: database access to integrated phenotype data., A W, Ringwald M, Sundberg JP, Bult CJ, Eppig JT Goldsmith C