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Submissions from 2008

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A critical window for experience-dependent plasticity at whisker sensory relay synapse in the thalamus., H Wang and Z W. Zhang

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Effects of exposing C57BL/6J mice to high- and low-frequency augmented acoustic environments: auditory brainstem response thresholds, cytocochleograms, anterior cochlear nucleus morphology and the role of gonadal hormones., J F. Willott, J VandenBosche, T Shimizu, D L. Ding, and R Salvi

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Cell adhesion to agrin presented as a nanopatterned substrate is consistent with an interaction with the extracellular matrix and not transmembrane adhesion molecules., T Wolfram, J P. Spatz, and R W. Burgess

Analyses of the role of endogenous SPARC in mouse models of prostate and breast cancer., S Y. Wong, D Crowley, R T. Bronson, and R O. Hynes

Membrane frizzled-related protein is necessary for the normal development and maintenance of photoreceptor outer segments., J Won, R S. Smith, N S. Peachey, J Wu, W L. Hicks, J K. Naggert, and P M. Nishina

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Multiple signaling pathways promote B lymphocyte stimulator dependent B-cell growth and survival., R T. Woodland, C J. Fox, M R. Schmidt, P S. Hammerman, J T. Opferman, S J. Korsmeyer, D M. Hilbert, and C B. Thompson

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A model for familial exudative vitreoretinopathy caused by LPR5 mutations., C H. Xia, H Liu, D Cheung, M Wang, C Cheng, X Du, B Chang, B Beutler, and X Gong

A close examination of genes within quantitative trait loci of bone mineral density in whole mouse genome., Q Xiong, C Han, W G. Beamer, and W Gu

Macrophage colony-stimulating factor is indispensable for repopulation and differentiation of Kupffer cells but not for splenic red pulp macrophages in osteopetrotic (op/op) mice after macrophage depletion., T Yamamoto, C Kaizu, T Kawasaki, G Hasegawa, H Umezu, R Ohashi, J Sakurada, S Jiang, L Shultz, and M Naito

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Randomization in laboratory procedure is key to obtaining reproducible microarray results., H Yang, C A. Harrington, K Vartanian, C D. Coldren, R Hall, and G A. Churchill

Submissions from 2007

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Integration of mouse phenome data resources. The Mouse Phenotype Database Integration Consortium.

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Neonatal FcR expression in bone marrow-derived cells functions to protect serum IgG from catabolism., S Akilesh, G J. Christianson, D C. Roopenian, and A S. Shaw

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Restoration of cone vision in a mouse model of achromatopsia., J J. Alexander, Y Umino, D Everhart, B Chang, S H. Min, Q Li, A M. Timmers, N L. Hawes, J J. Pang, R B. Barlow, and W W. Hauswirth

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Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch., D Amsen, A Antov, D Jankovic, A Sher, F Radtke, A Souabni, M Busslinger, B McCright, T Gridley, and R A. Flavell

Nanostructure analysis using spatially modulated illumination microscopy., D Baddeley, C Batram, Y Weiland, C Cremer, and U J. Birk

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A dominant, recombination-defective allele of Dmc1 causing male-specific sterility., L A. Bannister, R J. Pezza, J R. Donaldson, Rooij D. de, K J. Schimenti, Otero R. Camerini, and J C. Schimenti

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Genetic Manipulations of PPARs: Effects on Obesity and Metabolic Disease., Y Barak and S Kim

From whence will they come? - A perspective on the acute shortage of pathologists in biomedical research., S W. Barthold, A D. Borowsky, C Brayton, R Bronson, R D. Cardiff, S M. Griffey, T A. Ince, A Y. Nikitin, J Sundberg, V E. Valli, and J M. Ward

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Hepatic ABCG5/G8 overexpression reduces apoB-lipoproteins and atherosclerosis when cholesterol absorption is inhibited., F Basso, L A. Freeman, C Ko, C Joyce, M J. Amar, R D. Shamburek, T Tansey, F Thomas, J Wu, B Paigen, A T. Remaley, Fojo S. Santamarina, and H B. Brewer

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Genetic dissection of mouse distal chromosome 1 reveals three linked BMD QTLs with sex-dependent regulation of bone phenotypes., W G. Beamer, K L. Shultz, Bicknell C. Ackert, L G. Horton, K M. Delahunty, H F. Coombs, L R. Donahue, E Canalis, and C J. Rosen

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Mouse Tumor Biology Database (MTB): status update and future directions., D A. Begley, D M. Krupke, M J. Vincent, J P. Sundberg, C J. Bult, and J T. Eppig

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Inactivation of the UNC5C Netrin-1 receptor is associated with tumor progression in colorectal malignancies., A Bernet, L Mazelin, M M. Coissieux, N Gadot, S L. Ackerman, J Y. Scoazec, and P Mehlen

Breeding systems: considerations, genetic fundamentals, genetic background, and strain types., M L. Berry and C C. Linder

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Mouse Phenome Database (MPD)., M A. Bogue, S C. Grubb, T P. Maddatu, and C J. Bult

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Transcriptional profile of mouse pre-granulosa and Sertoli cells isolated from early-differentiated fetal gonads., G J. Bouma, J P. Affourtit, C J. Bult, and E M. Eicher

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Correct dosage of Fog2 and Gata4 transcription factors is critical for fetal testis development in mice., G J. Bouma, L L. Washburn, K H. Albrecht, and E M. Eicher

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A closer look: secondary glaucoma more likely., K Boyd, R S. Smith, A J. Funk, T D. Rogers, and R M. Dobbins

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Chromosome neighborhood composition determines translocation outcomes after exposure to high-dose radiation in primary cells., Caddle L. Brianna, J L. Grant, J Szatkiewicz, Hase J. van, B J. Shirley, J Bewersdorf, C Cremer, A Arneodo, A Khalil, and K D. Mills

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Genetic control of lipids in the mouse cross DU6i x DBA/2., G A. Brockmann, E Karatayli, C Neuschl, I M. Stylianou, S Aksu, A Ludwig, U Renne, C S. Haley, and S Knott

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Analysis of ocular hypopigmentation in Rab38cht/cht mice., B P. Brooks, D M. Larson, C C. Chan, S Kjellstrom, R S. Smith, M A. Crawford, L Lamoreux, M Huizing, R Hess, X Jiao, J F. Hejtmancik, A Maminishkis, S W. John, R Bush, and W J. Pavan

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Low utilization of circulating glucose after food withdrawal in Snell dwarf mice., N L. Brooks, C M. Trent, C F. Raetzsch, K Flurkey, G Boysen, M T. Perfetti, Y C. Jeong, S Klebanov, K B. Patel, V R. Khodush, L L. Kupper, D Carling, J A. Swenberg, D E. Harrison, and T P. Combs

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Rodent Lce gene clusters; new nomenclature, gene organization, and divergence of human and rodent genes., S J. Brown, C M. Tilli, B Jackson, A A. Avilion, M C. MacLeod, L J. Maltais, R C. Lovering, and C Byrne

Treatment of BXSB-Yaa mice with IL-21R-Fc fusion protein minimally attenuates systemic lupus erythematosus., J A. Bubier, S M. Bennett, T J. Sproule, B L. Lyons, S Olland, D A. Young, and D C. Roopenian

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Prediction of phenotype and gene expression for combinations of mutations., G W. Carter, S Prinz, C Neou, J P. Shelby, B Marzolf, V Thorsson, and T Galitski

The genetics of Alzheimer's disease., C K. Chai

Mouse models of RP., B Chang, N L. Hawes, M T. Davisson, and J R. Heckenlively

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Two mouse retinal degenerations caused by missense mutations in the beta-subunit of rod cGMP phosphodiesterase gene., B Chang, N L. Hawes, M T. Pardue, M T. Davisson, S Nusinowitz, S S. Sidney, R E. Stewart, R Chaudhury, J R. Heckenlively, and J H. Boatright

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Combined deletion of mouse dematin-headpiece and beta-adducin exerts a novel effect on the spectrin-actin junctions leading to erythrocyte fragility and hemolytic anemia., H Chen, A A. Khan, F Liu, D M. Gilligan, L L. Peters, J Messick, Hock W. Haschek, X Li, A E. Ostafin, and A H. Chishti

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Subcongenic analysis of genetic basis for impaired development of invariant NKT cells in NOD mice., Y G. Chen, J P. Driver, P A. Silveira, and D V. Serreze

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Cellular expression requirements for inhibition of type 1 diabetes by a dominantly protective major histocompatibility complex haplotype., Y G. Chen, P A. Silveira, M A. Osborne, H D. Chapman, and D V. Serreze

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Genetic and genomic insights into the molecular basis of atherosclerosis., Y Chen, J Rollins, B Paigen, and X Wang

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Elevated neuronal expression of CD200 protects Wlds mice from inflammation-mediated neurodegeneration., T Chitnis, J Imitola, Y Wang, W Elyaman, P Chawla, M Sharuk, K Raddassi, R T. Bronson, and S J. Khoury

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Impact of substrate glycoside linkage and elemental sulfur on bioenergetics of and hydrogen production by the hyperthermophilic archaeon Pyrococcus furiosus., C J. Chou, K R. Shockley, S B. Conners, D L. Lewis, D A. Comfort, M W. Adams, and R M. Kelly

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Hyperglycemia, maturity-onset obesity, and insulin resistance in NONcNZO10/LtJ males, a new mouse model of type 2 diabetes., Y R. Cho, H J. Kim, S Y. Park, H J. Ko, E G. Hong, T Higashimori, Z Zhang, D Y. Jung, M S. Ola, K F. Lanoue, E H. Leiter, and J K. Kim

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Recombinant inbred strain panels: a tool for systems genetics., G A. Churchill

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Mitochondria, redox signaling and axis specification in metazoan embryos., J A. Coffman and J M. Denegre

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The histone deacetylase HDAC4 connects neural activity to muscle transcriptional reprogramming., T J. Cohen, D S. Waddell, T Barrientos, Z Lu, G Feng, G A. Cox, S C. Bodine, and T P. Yao

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Neurobehavioral mutants identified in an ENU-mutagenesis project., M N. Cook, J P. Dunning, R G. Wiley, E J. Chesler, D K. Johnson, D R. Miller, and D Goldowitz

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Heat shock factor 1 is a powerful multifaceted modifier of carcinogenesis., C Dai, L Whitesell, A B. Rogers, and S Lindquist

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E2f4 is required for normal development of the airway epithelium., P S. Danielian, Kim C. Bender, A M. Caron, E Vasile, R T. Bronson, and J A. Lees

Euthanasia, P J. Danneman

Determinants of memory in experimental filarial infections in mice., Y Dash, M Ramesh, D Greiner, L D. Shultz, T R. Klei, and T V. Rajan

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Modifier locus for exencephaly in Cecr2 mutant mice is syntenic to the 10q25.3 region associated with neural tube defects in humans., C E. Davidson, Q Li, G A. Churchill, L R. Osborne, and H E. McDermid

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Impact of trisomy on fertility and meiosis in male mice., M Davisson, E Akeson, C Schmidt, B Harris, J Farley, and M A. Handel

Gene mapping., M T. Davisson

Cytogenetics., Muriel T. Davisson

Endocrinology: bone as a target tissue for hormonal regulation., K M. Delahunty and W G. Beamer

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Oocytes are required for the preantral granulosa cell to cumulus cell transition in mice., F J. Diaz, K Wigglesworth, and J J. Eppig

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Oocytes determine cumulus cell lineage in mouse ovarian follicles., F J. Diaz, K Wigglesworth, and J J. Eppig

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Ontology development for biological systems: immunology., A D. Diehl, J A. Lee, R H. Scheuermann, and J A. Blake

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UNC5C is required for spinal accessory motor neuron development., A K. Dillon, A R. Jevince, L Hinck, S L. Ackerman, X Lu, Lavigne M. Tessier, and Z Kaprielian

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Developmental biology. Home for the precious few., S DiNardo and R E. Braun

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LH analog and dietary isoflavones support ovarian granulosa cell tumor development in a spontaneous mouse model., A M. Dorward, K L. Shultz, and W G. Beamer

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Editing of the serotonin 2C receptor pre-mRNA: Effects of the Morris Water Maze., Y Du, M Stasko, A C. Costa, M T. Davisson, and K J. Gardiner

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Transcriptional profiling of androgen receptor (AR) mutants suggests instructive and permissive roles of AR signaling in germ cell development., S M. Eacker, J E. Shima, C M. Connolly, M Sharma, R W. Holdcraft, M D. Griswold, and R E. Braun

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Genetic regulation of femoral bone mineral density: complexity of sex effect in chromosome 1 revealed by congenic sublines of mice., B Edderkaoui, D J. Baylink, W G. Beamer, K L. Shultz, J E. Wergedal, and S Mohan

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Identification of mouse Duffy antigen receptor for chemokines (Darc) as a BMD QTL gene., B Edderkaoui, D J. Baylink, W G. Beamer, J E. Wergedal, R Porte, A Chaudhuri, and S Mohan

Genetic modifiers that affect phenotypic expression of retinal diseases., M M. Edwards, D M. Maddox, J Won, J K. Naggert, and P M. Nishina

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Neural logic molecular, counter-intuitive., I K. Egorov

Mouse strain and genetic nomenclature: an abbreviated guide., J T. Eppig

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The mouse genome database (MGD): new features facilitating a model system., J T. Eppig, J A. Blake, C J. Bult, J A. Kadin, and J E. Richardson

Mouse genome informatics (MGI) resources for pathology and toxicology., J T. Eppig, J A. Blake, C J. Bult, J E. Richardson, J A. Kadin, and M Ringwald

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Immunolocalization of enzymes, binding proteins, and receptors sufficient for retinoic acid synthesis and signaling during the hair cycle., H B. Everts, J P. Sundberg, L E. King, and D E. Ong

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Enhanced thymic selection of FoxP3+ regulatory T cells in the NOD mouse model of autoimmune diabetes., M Feuerer, W Jiang, P D. Holler, A Satpathy, C Campbell, M Bogue, D Mathis, and C Benoist

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PohnB6F1: a cross of wild and domestic mice that is a new model of extended female reproductive life span., K Flurkey, Y Brandvain, S Klebanov, S N. Austad, R A. Miller, R Yuan, and D E. Harrison

Mouse models in aging research., K Flurkey, J M. Currer, and D E. Harrison

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Distinct target-derived signals organize formation, maturation, and maintenance of motor nerve terminals., M A. Fox, J R. Sanes, D B. Borza, V P. Eswarakumar, R Fassler, B G. Hudson, S W. John, Y Ninomiya, V Pedchenko, S L. Pfaff, M N. Rheault, Y Sado, Y Segal, M J. Werle, and H Umemori

Genetic monitoring., R R. Fox, M V. Wiles, and P M. Petkov

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A sequence-based variation map of 8.27 million SNPs in inbred mouse strains., K A. Frazer, E Eskin, H M. Kang, M A. Bogue, D A. Hinds, E J. Beilharz, R V. Gupta, J Montgomery, M M. Morenzoni, G B. Nilsen, M J. Daly, C M. Wade, and D R. Cox

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Lipolytic and ligand-binding functions of hepatic lipase protect against atherosclerosis in LDL receptor-deficient mice., L Freeman, M J. Amar, R Shamburek, B Paigen, H B. Brewer, Fojo S. Santamarina, and Navarro H. Gonzalez

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Defects in eye development in transgenic mice overexpressing the heparan sulfate proteoglycan agrin., P G. Fuerst, S M. Rauch, and R W. Burgess

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Ena/VASP is required for endothelial barrier function in vivo., C Furman, A L. Sieminski, A V. Kwiatkowski, D A. Rubinson, E Vasile, R T. Bronson, R Fassler, and F B. Gertler

Low-level accelerations applied in the absence of weight bearing can enhance trabecular bone formation., R Garman, G Gaudette, L R. Donahue, C Rubin, and S Judex

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Genome-level analysis of genetic regulation of liver gene expression networks., D Gatti, A Maki, E J. Chesler, R Kirova, O Kosyk, L Lu, K F. Manly, R W. Williams, A Perkins, M A. Langston, D W. Threadgill, and I Rusyn

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mtDNA phylogeny and evolution of laboratory mouse strains., A Goios, L Pereira, M Bogue, V Macaulay, and A Amorim

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Col4a1 mutation causes endoplasmic reticulum stress and genetically modifiable ocular dysgenesis., D B. Gould, J K. Marchant, O V. Savinova, R S. Smith, and S W. John

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C. elegans sequences that control trans-splicing and operon pre-mRNA processing., J H. Graber, J Salisbury, L N. Hutchins, and T Blumenthal

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Notch signaling in vascular development and physiology., T Gridley

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Vascular biology: vessel guidance., T Gridley

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Laser surgery for mouse geneticists., T Gridley and R Woychik

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Modeling complex genetic interactions in a simple eukaryotic genome: actin displays a rich spectrum of complex haploinsufficiencies., B Haarer, S Viggiano, M A. Hibbs, O G. Troyanskaya, and D C. Amberg

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Mouse Phenotype Database Integration Consortium: integration [corrected] of mouse phenome data resources., J M. Hancock, N C. Adams, V Aidinis, A Blake, J A. Blake, M Bogue, E J. Chesler, J T. Eppig, C Smith, and et al

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Disruption of glomerular basement membrane charge through podocyte-specific mutation of agrin does not alter glomerular permselectivity., S J. Harvey, G Jarad, J Cunningham, A L. Rops, d e. van, J H. Berden, M J. Moeller, L B. Holzman, R W. Burgess, and J H. Miner

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Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors., J I. Herschkowitz, K Simin, V J. Weigman, I Mikaelian, J Usary, J Quackenbush, R I. Glazer, P H. Brown, J E. Green, L Kopelovich, P A. Furth, G A. Churchill, Dyke T. Van, and al et

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Dynamic clustered distribution of hemagglutinin resolved at 40 nm in living cell membranes discriminates between raft theories., S T. Hess, T J. Gould, M V. Gudheti, S A. Maas, K D. Mills, and J Zimmerberg

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Exploring the functional landscape of gene expression: directed search of large microarray compendia., M A. Hibbs, D C. Hess, C L. Myers, C Huttenhower, K Li, and O G. Troyanskaya

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Carbonic anhydrase related protein 8 mutation results in aberrant synaptic morphology and excitatory synaptic function in the cerebellum., M Hirasawa, X Xu, R B. Trask, T P. Maddatu, B A. Johnson, J K. Naggert, P M. Nishina, and A Ikeda

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Axons of retinal ganglion cells are insulted in the optic nerve early in DBA/2J glaucoma., G R. Howell, R T. Libby, T C. Jakobs, R S. Smith, F C. Phalan, J W. Barter, J M. Barbay, J K. Marchant, N Mahesh, V Porciatti, A V. Whitmore, R H. Masland, and S W. John

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Absence of glaucoma in DBA/2J mice homozygous for wild-type versions of Gpnmb and Tyrp1., G R. Howell, R T. Libby, J K. Marchant, L A. Wilson, I M. Cosma, R S. Smith, M G. Anderson, and S W. John

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Mutation of a ubiquitously expressed mouse transmembrane protein (Tapt1) causes specific skeletal homeotic transformations., G R. Howell, M Shindo, S Murray, T Gridley, L A. Wilson, and J C. Schimenti