Submissions from 2009
Devastation of bone tissue in the appendicular skeleton parallels the progression of neuromuscular disease., B J. Lee, G A. Cox, T P. Maddatu, S Judex, and C T. Rubin
A novel ENU-induced mutation, peewee, causes dwarfism in the mouse., B Lee, K Kano, J Young, S W. John, P M. Nishina, J K. Naggert, and K Naito
Caloric restriction in Alstrom syndrome prevents hyperinsulinemia., N C. Lee, J D. Marshall, G B. Collin, J K. Naggert, Y H. Chien, W Y. Tsai, and W L. Hwu
Selecting the "right" mouse model for metabolic syndrome and type 2 diabetes research., E H. Leiter
Type 1 diabetes genes in rats: few or many?, E H. Leiter
NOD x 129.H2(g7) backcross delineates 129S1/SvImJ-derived genomic regions modulating type 1 diabetes development in mice., E H. Leiter, P C. Reifsnyder, R Wallace, R Li, B King, and G C. Churchill
Using conventional fluorescent markers for far-field fluorescence localization nanoscopy allows resolution in the 10-nm range., P Lemmer, M Gunkel, Y Weiland, P Muller, D Baddeley, R Kaufmann, A Urich, H Eipel, R Amberger, M Hausmann, and C Cremer
The Human Genome Organisation (HUGO)., Edison T Liu
Gene therapy following subretinal AAV5 vector delivery is not affected by a previous intravitreal AAV5 vector administration in the partner eye., W Li, F Kong, Q Zheng, R Wu, X Zhou, F Lu, B Chang, W W. Hauswirth, J Qu, and al et
Smooth muscle Notch1 mediates neointimal formation after vascular injury., Y Li, K Takeshita, P Y. Liu, M Satoh, N Oyama, Y Mukai, M T. Chin, L Krebs, M I. Kotlikoff, F Radtke, T Gridley, and J K. Liao
Emu-BCL10 mice exhibit constitutive activation of both canonical and noncanonical NF-kappaB pathways generating marginal zone (MZ) B-cell expansion as a precursor to splenic MZ lymphoma., Z Li, H Wang, L Xue, D M. Shin, D Roopenian, W Xu, E Tuomanen, J E. Rehg, X Cui, Q Zhang, H C. Morse, and S W. Morris
Chromosome Y variants from different inbred mouse strains are linked to differences in the morphologic and molecular responses of cardiac cells to postpubertal testosterone., B Llamas, R A. Verdugo, G A. Churchill, and C F. Deschepper
Epiblast-specific Snai1 deletion results in embryonic lethality due to multiple vascular defects., H Lomeli, C Starling, and T Gridley
The nuclear periphery of embryonic stem cells is a transcriptionally permissive and repressive compartment., L Luo, K L. Gassman, L M. Petell, C L. Wilson, J Bewersdorf, and L S. Shopland
Mechanical stimulation of mesenchymal stem cell proliferation and differentiation promotes osteogenesis while preventing dietary-induced obesity., Y K. Luu, E Capilla, C J. Rosen, V Gilsanz, J E. Pessin, S Judex, and C T. Rubin
What are microarrays teaching us about sleep?, M Mackiewicz, J E. Zimmerman, K R. Shockley, G A. Churchill, and A I. Pack
Alcohol alters whole body composition, inhibits bone formation, and increases bone marrow adiposity in rats., G F. Maddalozzo, R T. Turner, C H. Edwards, K S. Howe, J J. Widrick, C J. Rosen, and U T. Iwaniec
Haploinsufficiency of AFG3L2, the gene responsible for spinocerebellar ataxia type 28, causes mitochondria-mediated Purkinje cell dark degeneration., F Maltecca, R Magnoni, F Cerri, G A. Cox, A Quattrini, and G Casari
Idd loci synergize to prolong islet allograft survival induced by costimulation blockade in NOD mice., J Mangada, T Pearson, M A. Brehm, L S. Wicker, L B. Peterson, L D. Shultz, D V. Serreze, A A. Rossini, and D L. Greiner
The podosomal-adaptor protein SH3PXD2B is essential for normal postnatal development., M Mao, D R. Thedens, B Chang, B S. Harris, Q Y. Zheng, K R. Johnson, L R. Donahue, and M G. Anderson
Deletion of the G protein-coupled receptor 30 impairs glucose tolerance, reduces bone growth, increases blood pressure, and eliminates estradiol-stimulated insulin release in female mice., U E. Martensson, S A. Salehi, S Windahl, M F. Gomez, K Sward, P O. Grande, C Owman, C J. Rosen, and al et
Transcriptome analysis reveals an unexpected role of a collagen tyrosine kinase receptor gene, Ddr2, as a regulator of ovarian function., H Matsumura, K Kano, de Evsikova Marin, J A. Young, P M. Nishina, J K. Naggert, and K Naito
Aag-initiated base excision repair drives alkylation-induced retinal degeneration in mice., L B. Meira, Erkul C. Moroski, S L. Green, J A. Calvo, R T. Bronson, D Shah, and L D. Samson
TLR agonists prevent the establishment of allogeneic hematopoietic chimerism in mice treated with costimulation blockade., D M. Miller, T B. Thornley, T Pearson, A J. Kruger, M Yamazaki, L D. Shultz, R M. Welsh, M A. Brehm, A A. Rossini, and D L. Greiner
A feedback loop involving the Phd3 prolyl hydroxylase tunes the mammalian hypoxic response in vivo., Y A. Minamishima, J Moslehi, R F. Padera, R T. Bronson, R Liao, and W G. Kaelin
Experimental characterization of 3D localization techniques for particle-tracking and super-resolution microscopy., M J. Mlodzianoski, M F. Juette, G L. Beane, and J Bewersdorf
Skeletal consequences of deletion of steroid receptor coactivator-2/transcription intermediary factor-2., U I. Modder, D G. Monroe, D G. Fraser, T C. Spelsberg, C J. Rosen, M Gehin, P Chambon, B W. O'Malley, and S Khosla
Mouse H6 Homeobox 1 (Hmx1) mutations cause cranial abnormalities and reduced body mass., R J. Munroe, V Prabhu, G M. Acland, K R. Johnson, B S. Harris, T P. O'Brien, I C. Welsh, D M. Noden, and J C. Schimenti
Retinoblastoma protein plays multiple essential roles in the terminal differentiation of Sertoli cells., R L. Nalam, Vieyra C. Andreu, R E. Braun, H Akiyama, and M M. Matzuk
Lung carcinogenesis induced by chronic tuberculosis infection: the experimental model and genetic control., A Nalbandian, B S. Yan, A Pichugin, R T. Bronson, and I Kramnik
Colocalization of somatic and meiotic double strand breaks near the Myc oncogene on mouse chromosome 15., S H. Ng, S A. Maas, P M. Petkov, K D. Mills, and K Paigen
Parental origin of chromosomes influences crossover activity within the Kcnq1 transcriptionally imprinted domain of Mus musculus., S H. Ng, R Madeira, E D. Parvanov, L M. Petros, P M. Petkov, and K Paigen
The response of C57BL/6J and BALB/cJ mice to increased housing density., A Nicholson, R D. Malcolm, P L. Russ, K Cough, C Touma, R Palme, and M V. Wiles
Inheritance patterns of progressive hearing loss in laboratory strains of mice., Trauth K. Noben and K R. Johnson
Protection from clinical peripheral sensory neuropathy in Alstrom syndrome in contrast to early-onset type 2 diabetes., R B. Paisey, R M. Paisey, M P. Thomson, L Bower, P Maffei, J P. Shield, S Barnett, and J D. Marshall
Heterozygous mutations of the voltage-gated sodium channel SCN8A are associated with spike-wave discharges and absence epilepsy in mice., L A. Papale, B Beyer, J M. Jones, L M. Sharkey, S Tufik, M Epstein, V A. Letts, M H. Meisler, W N. Frankel, and A Escayg
Inhibition of pituitary tumors in Rb mutant chimeras through E2f4 loss reveals a key suppressive role for the pRB/E2F pathway in urothelium and ganglionic carcinogenesis., T Parisi, R T. Bronson, and J A. Lees
Trans-regulation of mouse meiotic recombination hotspots by Rcr1., E D. Parvanov, S H. Ng, P M. Petkov, and K Paigen
HER2YVMA drives rapid development of adenosquamous lung tumors in mice that are sensitive to BIBW2992 and rapamycin combination therapy., S A. Perera, D Li, T Shimamura, M G. Raso, M Takahashi, L R. Chirieac, R F. Padera, R T. Bronson, and al et
Ott1 (Rbm15) is essential for placental vascular branching morphogenesis and embryonic development of the heart and spleen., G D. Raffel, G C. Chu, J L. Jesneck, D E. Cullen, R T. Bronson, O A. Bernard, and D G. Gilliland
Meiotic behavior of aneuploid chromatin in mouse models of Down syndrome., L G. Reinholdt, A Czechanski, S Kamdar, B L. King, F Sun, and M A. Handel
Distinguishing mouse strains by proteomic analysis of pelage hair., R H. Rice, D M. Rocke, H S. Tsai, K A. Silva, Y J. Lee, and J P. Sundberg
Jagged1 is the pathological link between Wnt and Notch pathways in colorectal cancer., Verónica Rodilla, Alberto Villanueva, Antonia Obrador-Hevia, Alex Robert-Moreno, Vanessa Fernández-Majada, Andrea Grilli, Nuria López-Bigas, Nicolás Bellora, M Mar Albà, Ferran Torres, Mireia Duñach, Xavier Sanjuan, Sara Gonzalez, Thomas Gridley, Gabriel Capella, Anna Bigas, and Lluís Espinosa
A Cmv2 QTL on chromosome X affects MCMV resistance in New Zealand male mice., M R. Rodriguez, A Lundgren, P Sabastian, Q Li, G Churchill, and M G. Brown
Bone: serotonin, leptin and the central control of bone remodeling., C J. Rosen
Breaking into bone biology: serotonin's secrets., C J. Rosen
Leptin's RIGHT turn to the brain stem., C J. Rosen
Serotonin rising--the bone, brain, bowel connection., C J. Rosen
Marrow fat and the bone microenvironment: developmental, functional, and pathological implications., C J. Rosen, Bicknell C. Ackert, J P. Rodriguez, and A M. Pino
Bone, fat, and body composition: evolving concepts in the pathogenesis of osteoporosis., C J. Rosen and A Klibanski
Supplementing high-density SNP microarrays for additional coverage of disease-related genes: addiction as a paradigm., S F. Saccone, L J. Bierut, E J. Chesler, P W. Kalivas, C Lerman, N L. Saccone, G R. Uhl, C Y. Li, V M. Philip, H J. Edenberg, S T. Sherry, M Feolo, R K. Moyzis, and J L. Rutter
Targeted deletion of the gamma-adducin gene (Add3) in mice reveals differences in alpha-adducin interactions in erythroid and nonerythroid cells., K E. Sahr, A J. Lambert, S L. Ciciotte, N Mohandas, and L L. Peters
New mouse models for recessive retinitis pigmentosa caused by mutations in the Pde6a gene., K Sakamoto, M McCluskey, T G. Wensel, J K. Naggert, and P M. Nishina
Probe-level analysis of expression microarrays characterizes isoform-specific degradation during mouse oocyte maturation., J Salisbury, K W. Hutchison, K Wigglesworth, J J. Eppig, and J H. Graber
PhenoGO: an integrated resource for the multiscale mining of clinical and biological data., L T. Sam, E A. Mendonca, J Li, J Blake, C Friedman, and Y A. Lussier
Filaggrin deficiency confers a paracellular barrier abnormality that reduces inflammatory thresholds to irritants and haptens., T C. Scharschmidt, M Q. Man, Y Hatano, D Crumrine, R Gunathilake, J P. Sundberg, K A. Silva, T M. Mauro, M Hupe, and al et
PRIME importance of pathology expertise., P N. Schofield, S D. Brown, J P. Sundberg, M Arends, M V. Warren, P Dubus, and al et
Post-publication sharing of data and tools., P N. Schofield, T Bubela, T Weaver, L Portilla, S D. Brown, J M. Hancock, D Einhorn, Valentini G. Tocchini, de Angelis Hrabe, N Rosenthal, and CASIMIR Rome Meeting participants
Notch signalling in the paraxial mesoderm is most sensitive to reduced Pofut1 levels during early mouse development., Gossler K. Schuster, B Harris, K R. Johnson, J Serth, and A Gossler
PPARgamma2 nuclear receptor controls multiple regulatory pathways of osteoblast differentiation from marrow mesenchymal stem cells., K R. Shockley, O P. Lazarenko, P J. Czernik, C J. Rosen, G A. Churchill, and Czernik B. Lecka
Effects of atherogenic diet on hepatic gene expression across mouse strains., K R. Shockley, D Witmer, Herbert S. Burgess, B Paigen, and G A. Churchill
Global changes in processing of mRNA 3' untranslated regions characterize clinically distinct cancer subtypes., P Singh, T L. Alley, S M. Wright, S Kamdar, W Schott, R Y. Wilpan, K D. Mills, and J H. Graber
The Mammalian Phenotype Ontology: enabling robust annotation and comparative analysis., C L. Smith and J T. Eppig
Quantitative trait locus analysis using J/qtl., R Smith, K Sheppard, K DiPetrillo, and G Churchill
Identification of genetic loci involved in diabetes using a rat model of depression., Woods L. Solberg, N Ahmadiyeh, A Baum, K Shimomura, Q Li, D F. Steiner, F W. Turek, J S. Takahashi, G A. Churchill, and E E. Redei
Reconstructing generalized logical networks of transcriptional regulation in mouse brain from temporal gene expression data., M J. Song, C K. Lewis, E R. Lance, E J. Chesler, R K. Yordanova, M A. Langston, K H. Lodowski, and S E. Bergeson
Novel ENU-induced point mutation in scavenger receptor class B, member 1, results in liver specific loss of SCARB1 protein., I M. Stylianou, K L. Svenson, S K. VanOrman, Y Langle, J S. Millar, B Paigen, and D J. Rader
Targeted suppression of Has2 mRNA in mouse cumulus cell-oocyte complexes by adenovirus-mediated short-hairpin RNA expression., K Sugiura, Y Q. Su, and J J. Eppig
Fibroblast growth factors and epidermal growth factor cooperate with oocyte-derived members of the TGFbeta superfamily to regulate Spry2 mRNA levels in mouse cumulus cells., K Sugiura, Y Q. Su, Q Li, K Wigglesworth, M M. Matzuk, and J J. Eppig
A data-capture tool for mouse pathology phenotyping., B A. Sundberg, P N. Schofield, M Gruenberger, and J P. Sundberg
A mouse by any other name ..., J P. Sundberg and P N. Schofield
One medicine, one pathology, and the one health concept., J P. Sundberg and P N. Schofield
Recombinant human hepatitis B vaccine initiating alopecia areata: testing the hypothesis using the C3H/HeJ mouse model., J P. Sundberg, K A. Silva, W Zhang, B A. Sundberg, K Edwards, L E. King, R L. Davis, and S Black
Where's the mouse info?, J P. Sundberg, J M. Ward, and P Schofield
Mouse oocyte control of granulosa cell development and function: paracrine regulation of cumulus cell metabolism., Y Q. Su, K Sugiura, and J J. Eppig
Farp2 and Stk25 are candidate genes for the HDL cholesterol locus on mouse chromosome 1., Z Su, A Cox, Y Shen, I M. Stylianou, and B Paigen
Four additional mouse crosses improve the lipid QTL landscape and identify Lipg as a QTL gene., Z Su, N Ishimori, Y Chen, E H. Leiter, G A. Churchill, B Paigen, and I M. Stylianou
Four additional mouse crosses improve the lipid QTL landscape and identify Lipg as a QTL gene., Z Su, N Ishimori, Y Chen, E H. Leiter, G A. Churchill, B Paigen, and I M. Stylianou
Genetic basis of HDL variation in 129/SvImJ and C57BL/6J mice: importance of testing candidate genes in targeted mutant mice., Z Su, X Wang, S W. Tsaih, A Zhang, A Cox, S Sheehan, and B Paigen
Bioluminescent imaging demonstrates that transplanted human embryonic stem cell-derived CD34(+) cells preferentially develop into endothelial cells., X Tian, M K. Hexum, V R. Penchev, R J. Taylor, L D. Shultz, and D S. Kaufman
Genetic complexity of absence seizures in substrains of C3H mice., S Tokuda, B J. Beyer, and W N. Frankel
DNA methyltransferase 1 is essential for and uniquely regulates hematopoietic stem and progenitor cells., Jennifer J. Trowbridge, Jonathan W Snow, Jonghwan Kim, and Stuart H Orkin
Haplotype association mapping in mice., S W. Tsaih and R Korstanje
Sepsis-induced human lymphocyte apoptosis and cytokine production in "humanized" mice., J Unsinger, J S. McDonough, L D. Shultz, T A. Ferguson, and R S. Hotchkiss
Importance of randomization in microarray experimental designs with Illumina platforms., R A. Verdugo, C F. Deschepper, G Munoz, D Pomp, and G A. Churchill
Androgen receptor in Sertoli cells is not required for testosterone-induced suppression of spermatogenesis, but contributes to Sertoli cell organization in Utp14b jsd mice., G Wang, C C. Weng, S H. Shao, W Zhou, Gendt K. de, R E. Braun, G Verhoeven, and M L. Meistrich
Degradation of IRS1 leads to impaired glucose uptake in adipose tissue of the type 2 diabetes mouse model TALLYHO/Jng., Y Wang, P M. Nishina, and J K. Naggert
A new mouse model of metabolic syndrome and associated complications., Y Wang, Y Zheng, P M. Nishina, and J K. Naggert
Single domain antibodies: promising experimental and therapeutic tools in infection and immunity., J Wesolowski, K Juarez, M Urrutia, A Cauerhff, F Scheuplein, D V. Serreze, F Haag, Nolte F. Koch, and al et
Antagonism of the testis- and ovary-determining pathways during ovotestis development in mice., D Wilhelm, L L. Washburn, V Truong, M Fellous, E M. Eicher, and P Koopman
RPGRIP1 is essential for normal rod photoreceptor outer segment elaboration and morphogenesis., J Won, E Gifford, R S. Smith, H Yi, P A. Ferreira, W L. Hicks, T Li, J K. Naggert, and P M. Nishina
Age, experience and genetic background influence treadmill walking in mice., C M. Wooley, S Xing, R W. Burgess, G A. Cox, and K L. Seburn
Complex oncogenic translocations with gene amplification are initiated by specific DNA breaks in lymphocytes., S M. Wright, Y H. Woo, T L. Alley, B J. Shirley, E C. Akeson, K J. Snow, S A. Maas, R L. Elwell, O Foreman, and K D. Mills
Understanding the muscular dystrophy caused by deletion of choline kinase beta in mice., G Wu, R B. Sher, G A. Cox, and D E. Vance
Genetic influence on electrocardiogram time intervals and heart rate in aging mice., S Xing, S W. Tsaih, R Yuan, K L. Svenson, L M. Jorgenson, M So, B J. Paigen, and R Korstanje
Quantitative trait loci, genes, and polymorphisms that regulate bone mineral density in mouse., Q Xiong, Y Jiao, K A. Hasty, S T. Canale, J M. Stuart, W G. Beamer, H W. Deng, D Baylink, and W Gu
A customized and versatile high-density genotyping array for the mouse., H Yang, Y Ding, L N. Hutchins, J Szatkiewicz, T A. Bell, B J. Paigen, J H. Graber, Villena F. de, and G A. Churchill
Aging in inbred strains of mice: study design and interim report on median lifespans and circulating IGF1 levels., Rong Yuan, Shirng-Wern Tsaih, Stefka B Petkova, Caralina Marin de Evsikova, Shuqin Xing, Michael A Marion, Molly A Bogue, Kevin D. Mills, Luanne L Peters, Carol J Bult, Clifford J Rosen, John P Sundberg, David E Harrison, Gary A Churchill, and Beverly Paigen