Submissions from 2009
Bone loss or lost bone: rationale and recommendations for the diagnosis and treatment of early postmenopausal bone loss., M Zaidi, C H. Turner, E Canalis, R Pacifici, L Sun, J Iqbal, X E. Guo, S Silverman, S Epstein, and C J. Rosen
A locus on distal chromosome 10 (ahl4) affecting age-related hearing loss in A/J mice., Q Y. Zheng, D Ding, H Yu, R J. Salvi, and K R. Johnson
MyD88 intrinsically regulates CD4 T-cell responses., S Zhou, Jones E. Kurt, A M. Cerny, M Chan, R T. Bronson, and R W. Finberg
Oncogenic EGFR signaling cooperates with loss of tumor suppressor gene functions in gliomagenesis., H Zhu, J Acquaviva, P Ramachandran, A Boskovitz, S Woolfenden, R Pfannl, R T. Bronson, J W. Chen, R Weissleder, D E. Housman, and A Charest
Submissions from 2008
Anesthesia and Analgesia in Laboratory Animals.
Mouse Models of Human Blood Cancers
The Gene Ontology project in 2008.
From ER to Eph receptors: new roles for VAP fragments., S L. Ackerman and G A. Cox
PPARG by dietary fat interaction influences bone mass in mice and humans., Bicknell C. Ackert, S Demissie, de Evsikova Marin, Y H. Hsu, V E. DeMambro, D Karasik, B Paigen, G A. Churchill, J Forejt, W G. Beamer, S Ferrari, M L. Bouxsein, D P. Kiel, and C J. Rosen
Human acute leukemia cells injected in NOD/LtSz-scid/IL-2Rgamma null mice generate a faster and more efficient disease compared to other NOD/scid-related strains., A Agliano, Padura I. Martin, P Mancuso, P Marighetti, C Rabascio, G Pruneri, L D. Shultz, and F Bertolini
Podocytes use FcRn to clear IgG from the glomerular basement membrane., S Akilesh, T B. Huber, H Wu, G Wang, B Hartleben, J B. Kopp, J H. Miner, D C. Roopenian, E R. Unanue, and A S. Shaw
Reduced DIDS-sensitive chloride conductance in Ae1-/- mouse erythrocytes., S L. Alper, D H. Vandorpe, L L. Peters, and C Brugnara
Iris phenotypes and pigment dispersion caused by genes influencing pigmentation., M G. Anderson, N L. Hawes, C M. Trantow, B Chang, and S W. John
GpnmbR150X allele must be present in bone marrow derived cells to mediate DBA/2J glaucoma., M G. Anderson, K S. Nair, L A. Amonoo, A Mehalow, C M. Trantow, S Masli, and S W. John
Identification of quantitative trait loci for locomotor activation and anxiety using closely-related inbred strains., J S. Bailey, Boase L. Grabowski, B M. Steffy, T Wiltshire, G A. Churchill, and L M. Tarantino
PPAR signaling in placental development and function., Y Barak, Y Sadovsky, and Barak T. Shalom
High precision size measurement of centromere 8 and the 8q24/c-myc gene region in metaphase and interphase human fibroblasts indicate differential condensation., C Batram, D Baddeley, G Kreth, and C Cremer
Absence seizures in C3H/HeJ and knockout mice caused by mutation of the AMPA receptor subunit Gria4., B Beyer, C Deleuze, V A. Letts, C L. Mahaffey, R M. Boumil, T A. Lew, J R. Huguenard, and W N. Frankel
Randomized trial of once-weekly parathyroid hormone (1-84) on bone mineral density and remodeling., D M. Black, M L. Bouxsein, L Palermo, J A. McGowan, D C. Newitt, E Rosen, S Majumdar, and C J. Rosen
The Gene Ontology (GO) project: structured vocabularies for molecular biology and their application to genome and expression analysis., J A. Blake and M A. Harris
Klebsiella oxytoca: opportunistic infections in laboratory rodents., A Bleich, P Kirsch, H Sahly, J Fahey, A Smoczek, H J. Hedrich, and J P. Sundberg
Sensitivity to Escherichia coli Nissle 1917 in mice is dependent on environment and genetic background., A Bleich, J P. Sundberg, A Smoczek, Wasielewski R. von, Buhr M. de, L M. Janus, G Julga, S N. Ukena, H J. Hedrich, and F Gunzer
Retrotransposon target site selection by imitation of a cellular protein., T L. Brady, P G. Fuerst, R A. Dick, C Schmidt, and D F. Voytas
The Mouse Genome Database (MGD): mouse biology and model systems., C J. Bult, J T. Eppig, J A. Kadin, J E. Richardson, and J A. Blake
Practical applications of the bioinformatics toolbox for narrowing quantitative trait Loci., Herbert S. Burgess, A Cox, S W. Tsaih, and B Paigen
Homologous recombination is necessary for normal lymphocyte development., L B. Caddle, M G. Hasham, W H. Schott, B J. Shirley, and K D. Mills
Characterization of glycolytic enzyme interactions with murine erythrocyte membranes in wild-type and membrane protein knockout mice., M E. Campanella, H Chu, N J. Wandersee, L L. Peters, N Mohandas, D M. Gilligan, and P S. Low
Replication of beta- and gammaretroviruses is restricted in I/LnJ mice via the same genetic mechanism., L K. Case, L Petell, L Yurkovetskiy, A Purdy, K J. Savage, and T V. Golovkina
Age-related retinal degeneration (arrd2) in a novel mouse model due to a nonsense mutation in the Mdm1 gene., B Chang, M N. Mandal, V R. Chavali, N L. Hawes, N W. Khan, R E. Hurd, R S. Smith, M L. Davisson, L Kopplin, B E. Klein, R Klein, S K. Iyengar, J R. Heckenlively, and R Ayyagari
Age-related eye diseases., Bo Chang
Rapid identification of MHC class I-restricted antigens relevant to autoimmune diabetes using retrogenic T cells., R J. Chaparro, A R. Burton, D V. Serreze, D A. Vignali, and T P. DiLorenzo
Mice expressing a mutant Krt75 (K6hf) allele develop hair and nail defects resembling pachyonychia congenita., J Chen, K Jaeger, Z Den, P J. Koch, J P. Sundberg, and D R. Roop
Commonalities of genetic resistance to spontaneous autoimmune and free radical--mediated diabetes., J Chen, Y Lu, C H. Lee, R Li, E H. Leiter, and C E. Mathews
Idd9/11 genetic locus regulates diabetogenic activity of CD4 T-cells in nonobese diabetic (NOD) mice., Y G. Chen, F Scheuplein, M A. Osborne, S W. Tsaih, H D. Chapman, and D V. Serreze
The Collaborative Cross at Oak Ridge National Laboratory: developing a powerful resource for systems genetics., E J. Chesler, D R. Miller, L R. Branstetter, L D. Galloway, B L. Jackson, V M. Philip, B H. Voy, C T. Culiat, D W. Threadgill, R W. Williams, G A. Churchill, D K. Johnson, and K F. Manly
Naive application of permutation testing leads to inflated type I error rates., G A. Churchill and R W. Doerge
Inflammation and autoimmunity caused by a SHP1 mutation depend on IL-1, MyD88, and a microbial trigger., B A. Croker, B R. Lawson, M Berger, C Eidenschenk, A L. Blasius, E M. Moresco, S Sovath, L Cengia, L D. Shultz, A N. Theofilopoulos, S Pettersson, and B A. Beutler
E2f3a and E2f3b make overlapping but different contributions to total E2f3 activity., P S. Danielian, L B. Friesenhahn, A M. Faust, J C. West, A M. Caron, R T. Bronson, and J A. Lees
Gender-specific changes in bone turnover and skeletal architecture in igfbp-2-null mice., V E. DeMambro, D R. Clemmons, L G. Horton, M L. Bouxsein, T L. Wood, W G. Beamer, E Canalis, and C J. Rosen
Minimum information specification for in situ hybridization and immunohistochemistry experiments (MISFISHIE)., E W. Deutsch, C A. Ball, J J. Berman, J Quackenbush, M Ringwald, G Sherlock, C J. Stoeckert, J Swedlow, R C. Taylor, L Walashek, and al et
Reprogramming and differentiation in mammals: motifs and mechanisms., Vries W. de, A V. Evsikov, L J. Brogan, C P. Anderson, J H. Graber, B B. Knowles, and D Solter
Regulation of Pcsk6 expression during the preantral to antral follicle transition in mice: opposing roles of FSH and oocytes., F J. Diaz, K Sugiura, and J J. Eppig
Influence of activation state of ErbB-2 (HER-2) on response to adjuvant cyclophosphamide, doxorubicin, and fluorouracil for stage II, node-positive breast cancer: study 8541 from the Cancer and Leukemia Group B., Michael P DiGiovanna, David F Stern, Susan Edgerton, Gloria Broadwater, Lynn G Dressler, Daniel R Budman, I Craig Henderson, Larry Norton, Edison Liu, Hyman B Muss, Donald A Berry, Daniel F Hayes, and Ann D Thor
Role of modulator recognition factor 2 in adipogenesis and leptin expression in 3T3-L1 cells., J Dong, N Ishimori, B Paigen, H Tsutsui, and S Fujii
Quantitative trait loci for urinary albumin in crosses between C57BL/6J and A/J inbred mice in the presence and absence of Apoe., C Doorenbos, S W. Tsaih, S Sheehan, N Ishimori, G Navis, G Churchill, K Dipetrillo, and R Korstanje
Functional annotation of protein isoforms and modified forms., H J. Drabkin, C N. Arighi, C H. Wu, and J A. Blake
Comparative therapeutic effects of orally administered 1,25-dihydroxyvitamin D(3) and 1alpha-hydroxyvitamin D(3) on type-1 diabetes in non-obese diabetic mice fed a normal-calcaemic diet., J P. Driver, O Foreman, C Mathieu, Etten E. van, and D V. Serreze
Hormonal regulation of testicular steroid and cholesterol homeostasis., S M. Eacker, N Agrawal, K Qian, H L. Dichek, E Y. Gong, K Lee, and R E. Braun
Editorial from the BOR Editors-in-Chief. The dreaded "d" word., J Eppig and M A. Handel
Effects of dietary restriction on hematopoietic stem-cell aging are genetically regulated., R P. Ertl, J Chen, C M. Astle, T M. Duffy, and D E. Harrison
Dietary restriction: a model system probing the cell fate decision between cancer and senescence., R P. Ertl and D E. Harrison
Repression of PTEN phosphatase by Snail1 transcriptional factor during gamma radiation-induced apoptosis., M Escriva, S Peiro, N Herranz, P Villagrasa, N Dave, Sentis B. Montserrat, S A. Murray, C Franci, T Gridley, I Virtanen, and de Herreros Garcia
A position effect on TRPS1 is associated with Ambras syndrome in humans and the Koala phenotype in mice., K A. Fantauzzo, Strapps M. Tadin, Y You, S E. Mentzer, F A. Baumeister, S Cianfarani, Maldergem L. Van, D Warburton, J P. Sundberg, and A M. Christiano
The effects of a high-fruit and -vegetable, high-fiber, low-fat dietary intervention on serum concentrations of insulin, glucose, IGF-I and IGFBP-3., A Flood, V Mai, R Pfeiffer, L Kahle, A T. Remaley, C J. Rosen, E Lanza, and A Schatzkin
PLoS Genetics turns three: looking back, looking ahead., W N. Frankel and G S. Barsh
Abnormal regulatory and effector T cell function predispose to autoimmunity following xenogeneic thymic transplantation., Y Fudaba, T Onoe, M Chittenden, A Shimizu, J M. Shaffer, R Bronson, and M Sykes
Neurite arborization and mosaic spacing in the mouse retina require DSCAM., P G. Fuerst, A Koizumi, R H. Masland, and R W. Burgess
Effects of buprenorphine on body temperature, locomotor activity and cardiovascular function when assessed by telemetric monitoring in rats., N M. Gades, P J. Danneman, S K. Wixson, and E A. Tolley
Mouse neutrophils lacking lamin B-receptor expression exhibit aberrant development and lack critical functional responses., P Gaines, C W. Tien, A L. Olins, D E. Olins, L D. Shultz, L Carney, and N Berliner
Cataracts in transgenic mice caused by a human papillomavirus type 18 E7 oncogene driven by KRT1-14., S Ghim, A B. Jenson, J A. Bubier, K A. Silva, R S. Smith, and J P. Sundberg
Expanded CD34+ human umbilical cord blood cells generate multiple lymphohematopoietic lineages in NOD-scid IL2rgamma(null) mice., L J. Giassi, T Pearson, L D. Shultz, J Laning, K Biber, M Kraus, B A. Woda, M R. Schmidt, R T. Woodland, A A. Rossini, and D L. Greiner
Toward optimal health: advances in diagnosis and preventive strategies to promote bone health in women., J R. Godfrey and C J. Rosen
Identification of mouse inbred strains through mitochondrial DNA single-nucleotide extension., A Goios, L Gusmao, A M. Rocha, A Fonseca, L Pereira, M Bogue, and A Amorim
A SNaPshot multiplex typing strategy for mtDNA identification of mouse inbred strains., Goios A, Gusmao L, Rocha AM, Pereira L, Bogue M, Amorim A
Asymmetry and polymorphism of hybrid male sterility during the early stages of speciation in house mice., J M. Good, M A. Handel, and M W. Nachman
Complex genetic regulation of bone mineral density and insulin-like growth factor-I in C57BL/6J-Chr #A/J/NaJ chromosome substitution strains., K E. Govoni, L R. Donahue, C Marden, and S Mohan
Mouse consomic strains: exploiting genetic divergence between Mus m. musculus and Mus m. domesticus subspecies., S Gregorova, P Divina, R Storchova, Z Trachtulec, V Fotopulosova, K L. Svenson, L R. Donahue, B Paigen, and J Forejt
A genomewide functional network for the laboratory mouse., Y Guan, C L. Myers, R Lu, I R. Lemischka, C J. Bult, and O G. Troyanskaya
Mapping of genetic modifiers of Nr2e3 rd7/rd7 that suppress retinal degeneration and restore blue cone cells to normal quantity., N B. Haider, W Zhang, R Hurd, A Ikeda, A M. Nystuen, J K. Naggert, and P M. Nishina
Cancer stem cells are enriched in the side population cells in a mouse model of glioma., M A. Harris, H Yang, B E. Low, J Mukherje, A Guha, R T. Bronson, L D. Shultz, M A. Israel, and K Yun
Members of the WNT signaling pathways are widely expressed in mouse ovaries, oocytes, and cleavage stage embryos., B N. Harwood, S K. Cross, E E. Radford, B E. Haac, and Vries W. De
Interaction between Reelin and Notch signaling regulates neuronal migration in the cerebral cortex., Torii K. Hashimoto, M Torii, M R. Sarkisian, C M. Bartley, J Shen, F Radtke, T Gridley, N Sestan, and P Rakic
Gene Ontology annotations: what they mean and where they come from., D P. Hill, B Smith, Hill M. McAndrews, and J A. Blake
Big data: The future of biocuration., D Howe, M Costanzo, P Fey, T Gojobori, L Hannick, W Hide, D P. Hill, R Kania, M Schaeffer, Pierre S. St, S Twigger, O White, and Rhee S. Yon
Mouse genetic models: an ideal system for understanding glaucomatous neurodegeneration and neuroprotection., Gareth R. Howell, R T. Libby, and Simon WN John
Mouse models: a key system in revolutionizing the understanding of glaucoma., Gareth R. Howell, J K. Marchant, and Simon WN John
A targeted deleterious allele of the splicing factor SCNM1 in the mouse., V M. Howell, Haan G. de, S Bergren, J M. Jones, C T. Culiat, E J. Michaud, W N. Frankel, and M H. Meisler
The mouse A/HeJ Y chromosome: another good Y gone bad., P A. Hunt, J M. Jackson, S Horan, C A. Lawson, L Grindell, L L. Washburn, and E M. Eicher
Position-dependent motif characterization using non-negative matrix factorization., L N. Hutchins, S M. Murphy, P Singh, and J H. Graber
Rapid conditional targeted ablation of cells expressing human CD59 in transgenic mice by intermedilysin., W Hu, S P. Ferris, R K. Tweten, G Wu, S Radaeva, B Gao, R T. Bronson, J A. Halperin, and X Qin
Expression of VLDLR in the retina and evolution of subretinal neovascularization in the knockout mouse model's retinal angiomatous proliferation., W Hu, A Jiang, J Liang, H Meng, B Chang, H Gao, and X Qiao
Genetic modeling of human blood cancers in mice., Y Hu and S Li
The RHOX5 homeodomain protein mediates transcriptional repression of the netrin-1 receptor gene Unc5c., Z Hu, S Shanker, J A. MacLean, S L. Ackerman, and M F. Wilkinson
Do-it-yourself (DIY) pathology., T A. Ince, J M. Ward, V E. Valli, D Sgroi, A Y. Nikitin, M Loda, S M. Griffey, C P. Crum, J M. Crawford, R T. Bronson, and R D. Cardiff
The Collaborative Cross, developing a resource for mammalian systems genetics: a status report of the Wellcome Trust cohort., F A. Iraqi, G Churchill, and R Mott
Modeling human leukemia using immune-compromised mice., F Ishikawa, Y Saito, and L D. Shultz
The differentiative and regenerative properties of human hematopoietic stem/progenitor cells in NOD-SCID/IL2rgamma(null) mice., F Ishikawa, Y Saito, S Yoshida, M Harada, and L D. Shultz
Quantitative trait loci for BMD in an SM/J by NZB/BlNJ intercross population and identification of Trps1 as a probable candidate gene., N Ishimori, I M. Stylianou, R Korstanje, M A. Marion, R Li, L R. Donahue, C J. Rosen, W G. Beamer, B Paigen, and G A. Churchill
Loss of apoptosis-inducing factor results in cell-type-specific neurogenesis defects., R Ishimura, G R. Martin, and S L. Ackerman
Effects of low-dose parathyroid hormone on bone mass, turnover, and ectopic osteoinduction in a rat model for chronic alcohol abuse., U T. Iwaniec, C H. Trevisiol, G F. Maddalozzo, C J. Rosen, and R T. Turner
VAC14 nucleates a protein complex essential for the acute interconversion of PI3P and PI(3,5)P(2) in yeast and mouse., N Jin, C Y. Chow, L Liu, S N. Zolov, R Bronson, M Davisson, J L. Petersen, Y Zhang, S Park, J E. Duex, D Goldowitz, M H. Meisler, and L S. Weisman
A locus on distal chromosome 11 (ahl8) and its interaction with Cdh23 ahl underlie the early onset, age-related hearing loss of DBA/2J mice., K R. Johnson, Guess C. Longo, L H. Gagnon, H Yu, and Q Y. Zheng
Three-dimensional sub-100 nm resolution fluorescence microscopy of thick samples., M F. Juette, T J. Gould, M D. Lessard, M J. Mlodzianoski, B S. Nagpure, B T. Bennett, S T. Hess, and J Bewersdorf
A novel dwarfism with gonadal dysfunction due to loss-of-function allele of the collagen receptor gene, Ddr2, in the mouse., K Kano, de Evsikova Marin, J Young, C Wnek, T P. Maddatu, P M. Nishina, and J K. Naggert
Strategies for assessing and minimizing pain., Karas AZ, Danneman PJ, Cadillac JM
Alopecia areata., L E. King, K J. McElwee, and J P. Sundberg
Humanized mice for the study of type 1 diabetes and beta cell function., M King, T Pearson, A A. Rossini, L D. Shultz, and D L. Greiner
A new Hu-PBL model for the study of human islet alloreactivity based on NOD-scid mice bearing a targeted mutation in the IL-2 receptor gamma chain gene., M King, T Pearson, L D. Shultz, J Leif, R Bottino, M Trucco, M A. Atkinson, C Wasserfall, K C. Herold, R T. Woodland, M R. Schmidt, B A. Woda, M J. Thompson, A A. Rossini, and D L. Greiner
CD34+CD38+CD19+ as well as CD34+CD38-CD19+ cells are leukemia-initiating cells with self-renewal capacity in human B-precursor ALL., Y Kong, S Yoshida, Y Saito, T Doi, Y Nagatoshi, M Fukata, D P. Lu, L D. Shultz, M Harada, and al et
Quantitative trait loci affecting phenotypic variation in the vacuolated lens mouse mutant, a multigenic mouse model of neural tube defects., R Korstanje, J Desai, G Lazar, B King, J Rollins, M Spurr, J Joseph, S Kadambi, Y Li, A Cherry, P G. Matteson, B Paigen, and J H. Millonig