Submissions from 2005
Early neoplastic and metastatic mammary tumours of transgenic mice detected by 5-aminolevulinic acid-stimulated protoporphyrin IX accumulation., A M. Dorward, K S. Fancher, T M. Duffy, W G. Beamer, and H Walt
Distal Chr 4 harbors a genetic locus (Gct1) fundamental for spontaneous ovarian granulosa cell tumorigenesis in a mouse model., A M. Dorward, K L. Shultz, L G. Horton, R Li, G A. Churchill, and W G. Beamer
Ontological visualization of protein-protein interactions., H J. Drabkin, C Hollenbeck, D P. Hill, and J A. Blake
Derivation of genetic interaction networks from quantitative phenotype data., B L. Drees, V Thorsson, G W. Carter, A W. Rives, M Z. Raymond, Campillo I. Avila, P Shannon, and T Galitski
Comparison of HER2 status by fluorescence in situ hybridization and immunohistochemistry to predict benefit from dose escalation of adjuvant doxorubicin-based therapy in node-positive breast cancer patients., Lynn G Dressler, Donald A Berry, Gloria Broadwater, David Cowan, Kelly Cox, Stephanie Griffin, Ashley Miller, Jessica Tse, Debra Novotny, Diane L Persons, Maurice Barcos, I Craig Henderson, Edison T. Liu, Ann Thor, Dan Budman, Hy Muss, Larry Norton, and Daniel F Hayes
Mouse oocytes control metabolic co-operativity between oocytes and cumulus cells., J J. Eppig
Mouse oocytes regulate metabolic cooperativity between granulosa cells and oocytes: amino Acid transport., J J. Eppig, F L. Pendola, K Wigglesworth, and J K. Pendola
The Mouse Genome Database (MGD): from genes to mice--a community resource for mouse biology., J T. Eppig, C J. Bult, J A. Kadin, J E. Richardson, and J A. Blake
Immunolocalization of retinoic acid biosynthesis systems in selected sites in rat., H B. Everts, J P. Sundberg, and D E. Ong
The Pim kinases control rapamycin-resistant T cell survival and activation., C J. Fox, P S. Hammerman, and C B. Thompson
Introducing PLoS Genetics., W N. Frankel
Development of a new genetic model for absence epilepsy: spike-wave seizures in C3H/He and backcross mice., W N. Frankel, B Beyer, C R. Maxwell, S Pretel, V A. Letts, and S J. Siegel
Reduced expression of interleukin-2 decreases the frequency of alopecia areata onset in C3H/HeJ mice., Paul P. Freyschmidt, K J. McElwee, R Hoffmann, J P. Sundberg, S Kissling, S Hummel, M Vitacolonna, Schneider A. Kopp, and M Zoller
The functional relevance of the type 1 cytokines IFN-gamma and IL-2 in alopecia areata of C3H/HeJ mice., Paul P. Freyschmidt, M Zoller, K J. McElwee, J Sundberg, R Happle, and R Hoffmann
Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells., T Fujiwara, M Bandi, M Nitta, E V. Ivanova, R T. Bronson, and D Pellman
Report on the 'Expert Workshop on the Biology of Chromosome 21: towards gene-phenotype correlations in Down syndrome', held June 11-14, 2004, Washington D.C., K Gardiner, M T. Davisson, M Pritchard, D Patterson, Y Groner, L S. Crnic, S Antonarakis, and W Mobley
Autoimmune diabetes and resistance to xenograft transplantation tolerance in NOD mice., E J. Gordon, L S. Wicker, L B. Peterson, D V. Serreze, T G. Markees, L D. Shultz, A A. Rossini, D L. Greiner, and J P. Mordes
Mutations in Col4a1 cause perinatal cerebral hemorrhage and porencephaly., D B. Gould, F C. Phalan, G J. Breedveld, Mil S. van, R S. Smith, J C. Schimenti, U Aguglia, der Knaap van, P Heutink, and S W. John
Diminished gallbladder motility in rotund leptin-resistant obese mice., S J. Graewin, K Q. Tran, J K. Naggert, K H. Lee, Basile D. Swartz, A Nakeeb, and H A. Pitt
Ethics: Moral issues of human-non-human primate neural grafting., M Greene, K Schill, S Takahashi, T Beauchamp, H Bok, S Goldman, H Greely, L Martin, E Miller, A Siegel, D Solter, R Faden, and al et
An improved technique for tail-cuff blood pressure measurements with dark-tailed mice., J R. Hagaman, S John, L Xu, O Smithies, and N Maeda
Pim and Akt oncogenes are independent regulators of hematopoietic cell growth and survival., P S. Hammerman, C J. Fox, M J. Birnbaum, and C B. Thompson
Regulation of meiotic cell divisions and determination of gamete quality: impact of reproductive toxins., M A. Handel and F Sun
The Adult Mouse Anatomical Dictionary: a tool for annotating and integrating data., T F. Hayamizu, M Mangan, J P. Corradi, J A. Kadin, and M Ringwald
The Tetratricopeptide repeat domain 7 gene is mutated in flaky skin mice: a model for psoriasis, autoimmunity, and anemia., C Helms, S Pelsue, L Cao, E Lamb, B Loffredo, Miller P. Taillon, B Herrin, L M. Burzenski, B Gott, B L. Lyons, D Keppler, L D. Shultz, and A M. Bowcock
Visualization methods for statistical analysis of microarray clusters., M A. Hibbs, N C. Dirksen, K Li, and O G. Troyanskaya
Reprogramming is essential in nuclear transfer., T Hiiragi and D Solter
Familial variable expression of dilated cardiomyopathy in Alstrom syndrome: A report of four sibs., J D. Hoffman, Z Jacobson, T L. Young, J D. Marshall, and P Kaplan
SHP-1 regulates STAT6 phosphorylation and IL-4-mediated function in a cell type-specific manner., Z Huang, J M. Coleman, Y Su, M Mann, J Ryan, L D. Shultz, and H Huang
Mdm muscular dystrophy: interactions with calpain 3 and a novel functional role for titin's N2A domain., K A. Huebsch, E Kudryashova, C M. Wooley, R B. Sher, K L. Seburn, M J. Spencer, and G A. Cox
Perp is a p63-regulated gene essential for epithelial integrity., R A. Ihrie, M R. Marques, B T. Nguyen, J S. Horner, C Papazoglu, R T. Bronson, A A. Mills, and L D. Attardi
Genetic differences in the IGF-I gene among inbred strains of mice with different serum IGF-I levels., K Iida, C J. Rosen, Bicknell C. Ackert, and M O. Thorner
Development of functional human blood and immune systems in NOD/SCID/IL2 receptor {gamma} chain(null) mice., F Ishikawa, M Yasukawa, B Lyons, S Yoshida, T Miyamoto, G Yoshimoto, T Watanabe, K Akashi, L D. Shultz, and M Harada
Disruption of the Jnk2 (Mapk9) gene reduces destructive insulitis and diabetes in a mouse model of type I diabetes., A Jaeschke, M Rincon, B Doran, J Reilly, D Neuberg, D L. Greiner, L D. Shultz, A A. Rossini, R A. Flavell, and R J. Davis
Retinal ganglion cell degeneration is topological but not cell type specific in DBA/2J mice., T C. Jakobs, R T. Libby, Y Ben, S W. John, and R H. Masland
A deletion causing spontaneous fracture identified from a candidate region of mouse Chromosome 14., Y Jiao, X Li, W G. Beamer, J Yan, Y Tong, D Goldowitz, B Roe, and W Gu
Carbonic anhydrase-related protein VIII deficiency is associated with a distinctive lifelong gait disorder in waddles mice., Y Jiao, J Yan, Y Zhao, L R. Donahue, W G. Beamer, X Li, B A. Roe, M S. Ledoux, and W Gu
The Mass1(frings) mutation underlies early onset hearing impairment in BUB/BnJ mice, a model for the auditory pathology of Usher syndrome IIC., K R. Johnson, Q Y. Zheng, M D. Weston, L J. Ptacek, and Trauth K. Noben
Mechanistic insights into glaucoma provided by experimental genetics the cogan lecture., S W. John
A quantitative survey of gravity receptor function in mutant mouse strains., S M. Jones, K R. Johnson, H Yu, L C. Erway, K N. Alagramam, N Pollak, and T A. Jones
Mechanical modulation of molecular signals which regulate anabolic and catabolic activity in bone tissue., S Judex, N Zhong, M E. Squire, K Ye, L R. Donahue, M Hadjiargyrou, and C T. Rubin
P2X7 receptor-dependent and -independent T cell death is induced by nicotinamide adenine dinucleotide., H Kawamura, F Aswad, M Minagawa, K Malone, H Kaslow, Nolte F. Koch, W H. Schott, E H. Leiter, and G Dennert
Efficient engraftment of primary adult T-cell leukemia cells in newborn NOD/SCID/beta2-microglobulin(null) mice., N Kawano, F Ishikawa, K Shimoda, M Yasukawa, K Nagafuji, T Miyamoto, E Baba, T Tanaka, S Yamasaki, H Gondo, T Otsuka, K Ohshima, L D. Shultz, K Akashi, and M Harada
Urogenital and caudal dysgenesis in adrenocortical dysplasia (acd) mice is caused by a splicing mutation in a novel telomeric regulator., C E. Keegan, J E. Hutz, T Else, M Adamska, S P. Shah, A E. Kent, J M. Howes, W G. Beamer, and G D. Hammer
Cu/Zn superoxide dismutase and age-related hearing loss., E M. Keithley, C Canto, Q Y. Zheng, X Wang, Ghodsian N. Fischel, and K R. Johnson
A torrid zone on mouse chromosome 1 containing a cluster of recombinational hotspots., P M. Kelmenson, P Petkov, X Wang, D C. Higgins, B J. Paigen, and K Paigen
Biodistribution of (225)Ra citrate in mice: retention of daughter radioisotopes in bone., S J. Kennel, T Lankford, M Garland, J P. Sundberg, and S Mirzadeh
Simultaneous serodetection of 10 highly prevalent mouse infectious pathogens in a single reaction by multiplex analysis., I H. Khan, L V. Kendall, M Ziman, S Wong, S Mendoza, J Fahey, S M. Griffey, S W. Barthold, and P A. Luciw
The Notch ligands DLL1 and JAG2 act synergistically to regulate hair cell development in the mammalian inner ear., A E. Kiernan, R Cordes, R Kopan, A Gossler, and T Gridley
Identification of bronchioalveolar stem cells in normal lung and lung cancer., C F. Kim, E L. Jackson, A E. Woolfenden, S Lawrence, I Babar, S Vogel, D Crowley, R T. Bronson, and T Jacks
Type 2 diabetes mouse model TallyHo carries an obesity gene on chromosome 6 that exaggerates dietary obesity., J H. Kim, T P. Stewart, W Zhang, H Y. Kim, P M. Nishina, and J K. Naggert
Effects of growth hormone transgene expression on vertebrae in a mouse model of osteogenesis imperfecta., D King, J Chase, R M. Havey, L Voronov, M Sartori, H A. McEwen, W G. Beamer, and A G. Patwardhan
Proteasome Inhibition Alters Glucose-stimulated (Pro)insulin Secretion and Turnover in Pancreatic {beta}-Cells., K Kitiphongspattana, C E. Mathews, E H. Leiter, and H R. Gaskins
Adipose tissue transplantation protects ob/ob mice from obesity, normalizes insulin sensitivity and restores fertility., S Klebanov, C M. Astle, O DeSimone, V Ablamunits, and D E. Harrison
Targeted ablation of the abcc6 gene results in ectopic mineralization of connective tissues., J F. Klement, Y Matsuzaki, Q J. Jiang, J Terlizzi, H Y. Choi, N Fujimoto, K Li, L Pulkkinen, D E. Birk, J P. Sundberg, and J Uitto
p53 is a suppressor of inflammatory response in mice., E A. Komarova, V Krivokrysenko, K Wang, N Neznanov, M V. Chernov, P G. Komarov, M L. Brennan, T V. Golovkina, O W. Rokhlin, D V. Kuprash, S A. Nedospasov, S L. Hazen, E Feinstein, and A V. Gudkov
CD38 controls ADP-ribosyltransferase-2-catalyzed ADP-ribosylation of T cell surface proteins., C Krebs, S Adriouch, F Braasch, W Koestner, E H. Leiter, M Seman, F E. Lund, N Oppenheimer, F Haag, and Nolte F. Koch
The Mouse Tumor Biology Database: integrated access to mouse cancer biology data., D Krupke, D Naf, M Vincent, T Allio, I Mikaelian, J Sundberg, C Bult, and J Eppig
Archiving mouse strains by cryopreservation., C P. Landel
Correlations between edema and the immediate and prolonged painful consequences of inflammation: therapeutic implications?, W R. Lariviere, E J. Chesler, Z Li, G W. Shang, Y N. Chen, Y Q. Yu, Z M. Lu, Y Chang, C Luo, K C. Li, and J Chen
Novel leptin receptor mutation in NOD/LtJ mice suppresses type 1 diabetes progression: I. Pathophysiological analysis., C H. Lee, P C. Reifsnyder, J K. Naggert, C Wasserfall, M A. Atkinson, J Chen, and E H. Leiter
Ocular abnormalities in Large(myd) and Large(vls) mice, spontaneous models for muscle, eye, and brain diseases., Y Lee, S Kameya, G A. Cox, J Hsu, W Hicks, T P. Maddatu, R S. Smith, J K. Naggert, N S. Peachey, and P M. Nishina
Nonobese diabetic mice and the genetics of diabetes susceptibility., E H. Leiter
Mouse models and the genetics of diabetes: is there evidence for genetic overlap between type 1 and type 2 diabetes?, E H. Leiter and C H. Lee
Stargazer-a mouse to seize!, V A. Letts
A targeted mutation in Cacng4 exacerbates spike-wave seizures in stargazer (Cacng2) mice., V A. Letts, C L. Mahaffey, B Beyer, and W N. Frankel
Inherited glaucoma in DBA/2J mice: pertinent disease features for studying the neurodegeneration., R T. Libby, M G. Anderson, I H. Pang, Z H. Robinson, O V. Savinova, I M. Cosma, A Snow, L A. Wilson, R S. Smith, A F. Clark, and S W. John
Complex genetics of glaucoma susceptibility., R T. Libby, D B. Gould, M G. Anderson, and S W. John
Susceptibility to neurodegeneration in a glaucoma is modified by Bax gene dosage., R T. Libby, Y Li, O V. Savinova, J Barter, R S. Smith, R W. Nickells, and S W. John
Inferring gene transcriptional modulatory relations: a genetical genomics approach., H Li, L Lu, K F. Manly, E J. Chesler, L Bao, J Wang, M Zhou, R W. Williams, and Y Cui
Essential role of endothelial Notch1 in angiogenesis., F P. Limbourg, K Takeshita, F Radtke, R T. Bronson, M T. Chin, and J K. Liao
Complete FcRn dependence for intravenous Ig therapy in autoimmune skin blistering diseases., N Li, M Zhao, Vargas J. Hilario, P Prisayanh, S Warren, L A. Diaz, D C. Roopenian, and Z Liu
Combining data from multiple inbred line crosses improves the power and resolution of quantitative trait Loci mapping., R Li, M A. Lyons, H Wittenburg, B Paigen, and G A. Churchill
Src kinases as targets for B cell acute lymphoblastic leukaemia therapy., S Li
Restricted MHC-peptide repertoire predisposes to autoimmunity., N N. Logunova, C Viret, L A. Pobezinsky, S A. Miller, D B. Kazansky, J P. Sundberg, and A V. Chervonsky
A missense mutation in the previously undescribed gene Tmhs underlies deafness in hurry-scurry (hscy) mice., Guess C. Longo, L H. Gagnon, S A. Cook, J Wu, Q Y. Zheng, and K R. Johnson
Single and interacting QTLs for cholesterol gallstones revealed in an intercross between mouse strains NZB and SM., M A. Lyons, R Korstanje, R Li, S M. Sheehan, K A. Walsh, J A. Rollins, M C. Carey, B Paigen, and G A. Churchill
Humanized mice: are we there yet?, F Macchiarini, M G. Manz, A K. Palucka, and L D. Shultz
Development of intestinal M cells., J Mach, T Hshieh, D Hsieh, N Grubbs, and A Chervonsky
Dilated cardiomyopathy in the nmd mouse: transgenic rescue and QTLs that improve cardiac function and survival., T P. Maddatu, S M. Garvey, D G. Schroeder, W Zhang, S Y. Kim, A I. Nicholson, C J. Davis, and G A. Cox
Mice lacking the p53/p63 target gene Perp are resistant to papilloma development., M R. Marques, J S. Horner, R A. Ihrie, R T. Bronson, and L D. Attardi
New Alstrom syndrome phenotypes based on the evaluation of 182 cases., J D. Marshall, R T. Bronson, G B. Collin, A D. Nordstrom, P Maffei, R B. Paisey, C Carey, S Macdermott, Eggitt I. Russell, S E. Shea, J Davis, S Beck, G Shatirishvili, C M. Mihai, M Hoeltzenbein, G B. Pozzan, I Hopkinson, N Sicolo, J K. Naggert, and P M. Nishina
Behavioral, cognitive and biochemical responses to different environmental conditions in male Ts65Dn mice, a model of Down syndrome., Cue C. Martinez, N Rueda, E Garcia, M T. Davisson, C Schmidt, and J Florez
Notch signaling coordinates the patterning of striatal compartments., H A. Mason, S M. Rakowiecki, M Raftopoulou, S Nery, Y Huang, T Gridley, and G Fishell
mt-Nd2 Allele of the ALR/Lt mouse confers resistance against both chemically induced and autoimmune diabetes., C E. Mathews, E H. Leiter, O Spirina, Y Bykhovskaya, A M. Gusdon, S Ringquist, and Ghodsian N. Fischel
Complex genetics of interactions of alcohol and CNS function and behavior., D B. Matthews, S V. Bhave, J K. Belknap, C Brittingham, E J. Chesler, R J. Hitzemann, P L. Hoffmann, L Lu, S McWeeney, M F. Miles, B Tabakoff, and R W. Williams
Selective ablation of alphav integrins in the central nervous system leads to cerebral hemorrhage, seizures, axonal degeneration and premature death., J H. McCarty, Hulbert A. Lacy, A Charest, R T. Bronson, D Crowley, D Housman, J Savill, J Roes, and R O. Hynes
Androgens regulate the permeability of the blood-testis barrier., J Meng, R W. Holdcraft, J E. Shima, M D. Griswold, and R E. Braun
Heritability, correlations and in silico mapping of locomotor behavior and neurochemistry in inbred strains of mice., T R. Mhyre, E J. Chesler, M Thiruchelvam, C Lungu, Slechta D. Cory, J D. Fry, and E K. Richfield
An assay for human hematopoietic stem cells based on transplantation into nonobese diabetic recombination activating gene-null perforin-null mice., H Minamiguchi, J R. Wingard, J H. Laver, E S. Mainali, L D. Shultz, and M Ogawa
Variable sensitivity to noxious heat is mediated by differential expression of the CGRP gene., J S. Mogil, F Miermeister, F Seifert, K Strasburg, K Zimmermann, H Reinold, J S. Austin, N Bernardini, E J. Chesler, H A. Hofmann, and al et
Spontaneous fractures in the mouse mutant sfx are caused by deletion of the gulonolactone oxidase gene, causing vitamin C deficiency., S Mohan, A Kapoor, A Singgih, Z Zhang, T Taylor, H Yu, R B. Chadwick, Y S. Chung, L R. Donahue, C Rosen, G C. Crawford, J Wergedal, and D J. Baylink
Polarity of the mouse embryo is established at blastocyst and is not prepatterned., N Motosugi, T Bauer, Z Polanski, D Solter, and T Hiiragi
Kinesin family member 12 is a candidate polycystic kidney disease modifier in the cpk mouse., M Mrug, R Li, X Cui, T R. Schoeb, G A. Churchill, and Woodford L. Guay
Discovery of biological networks from diverse functional genomic data., C L. Myers, D Robson, A Wible, M A. Hibbs, C Chiriac, C L. Theesfeld, K Dolinski, and O G. Troyanskaya
The insulin-like growth factor-I gene and osteoporosis: A critical appraisal., T Niu and C J. Rosen
nm1054: a spontaneous, recessive, hypochromic, microcytic anemia mutation in the mouse., R S. Ohgami, D R. Campagna, B Antiochos, E B. Wood, J J. Sharp, J E. Barker, and M D. Fleming
Identification of a ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells., R S. Ohgami, D R. Campagna, E L. Greer, B Antiochos, A McDonald, J Chen, J J. Sharp, Y Fujiwara, J E. Barker, and M D. Fleming
Direct regulatory role of NKT cells in allogeneic graft survival is dependent on the quantitative strength of antigenicity., K Oh, S Kim, S H. Park, H Gu, D Roopenian, D H. Chung, Y S. Kim, and D S. Lee
Variation in IL-1beta gene expression is a major determinant of genetic differences in arthritis aggressivity in mice., K Ohmura, A Johnsen, Lopez A. Ortiz, P Desany, M Roy, W Besse, J Rogus, M Bogue, A Puech, M Lathrop, D Mathis, and C Benoist