Submissions from 2014
The Human Phenotype Ontology project: linking molecular biology and disease through phenotype data., Sebastian Köhler, Sandra C Doelken, Christopher J Mungall, Sebastian Bauer, Helen V Firth, Isabelle Bailleul-Forestier, Graeme C M Black, Danielle L Brown, Michael Brudno, Jennifer Campbell, David R Fitzpatrick, Janan T. Eppig, Andrew P Jackson, Kathleen Freson, Marta Girdea, Ingo Helbig, Jane A Hurst, Johanna Jähn, Laird G Jackson, Anne M Kelly, David H Ledbetter, Sahar Mansour, Christa L Martin, Celia Moss, Andrew Mumford, Willem H Ouwehand, Soo-Mi Park, Erin Rooney Riggs, Richard H Scott, Sanjay Sisodiya, Steven Van Vooren, Ronald J Wapner, Andrew O M Wilkie, Caroline F Wright, Anneke T Vulto-van Silfhout, Nicole de Leeuw, Bert B A de Vries, Nicole L Washingthon, Cynthia Smith, Monte Westerfield, Paul Schofield, Barbara J Ruef, Georgios V Gkoutos, Melissa Haendel, Damian Smedley, Suzanna E Lewis, and Peter N Robinson
A mouse Col4a4 mutation causing Alport glomerulosclerosis with abnormal collagen α3α4α5(IV) trimers., Ron Korstanje, Christina R Caputo, Rosalinda A. Doty, Susan A. Cook, Roderick T Bronson, Muriel T. Davisson, and Jeffrey H Miner
A Common Functional Regulatory Variant at a Type 2 Diabetes Locus Upregulates ARAP1 Expression in the Pancreatic Beta Cell., Jennifer R Kulzer, Michael L. Stitzel, Mario A Morken, Jeroen R Huyghe, Christian Fuchsberger, Johanna Kuusisto, Markku Laakso, Michael Boehnke, Francis S Collins, and Karen L Mohlke
Genomic encyclopedia of bacteria and archaea: sequencing a myriad of type strains., Nikos C Kyrpides, Philip Hugenholtz, Jonathan A Eisen, Tanja Woyke, Markus Göker, Charles T Parker, Rudolf Amann, Brian J Beck, Patrick S G Chain, Jongsik Chun, Rita R Colwell, Antoine Danchin, Peter Dawyndt, Tom Dedeurwaerdere, Edward F DeLong, John C Detter, Paul De Vos, Timothy J Donohue, Xiu-Zhu Dong, Dusko S Ehrlich, Claire Fraser, Richard Gibbs, Jack Gilbert, Paul Gilna, Frank Oliver Glöckner, Janet K Jansson, Jay D Keasling, Rob Knight, David Labeda, Alla Lapidus, Jung-Sook Lee, Wen-Jun Li, Juncai Ma, Victor Markowitz, Edward R B Moore, Mark Morrison, Folker Meyer, Karen E Nelson, Moriya Ohkuma, Christos A Ouzounis, Norman Pace, Julian Parkhill, Nan Qin, Ramon Rossello-Mora, Johannes Sikorski, David Smith, Mitch Sogin, Rick Stevens, Uli Stingl, Ken-Ichiro Suzuki, Dorothea Taylor, Jim M Tiedje, Brian Tindall, Michael Wagner, George M. Weinstock, Jean Weissenbach, Owen White, Jun Wang, Lixin Zhang, Yu-Guang Zhou, Dawn Field, William B Whitman, George M Garrity, and Hans-Peter Klenk
Compensatory mechanisms allow undersized anchor-deficient class I MHC ligands to mediate pathogenic autoreactive T cell responses., Deanna Lamont, Gayatri Mukherjee, P Rajesh Kumar, Dibyendu Samanta, Caroline G. McPhee, Thomas W H Kay, Steven C Almo, Teresa P DiLorenzo, and David V. Serreze
Patterned progression of bacterial populations in the premature infant gut., Patricio S La Rosa, Barbara B Warner, Yanjiao Zhou, George M. Weinstock, Erica Sodergren Weinstock, Carla M Hall-Moore, Harold J Stevens, William E Bennett, Nurmohammad Shaikh, Laura A Linneman, Julie A Hoffmann, Aaron Hamvas, Elena Deych, Berkley A Shands, William D Shannon, and Phillip I Tarr
Hidden in plain sight: spike-wave discharges in mouse inbred strains., Verity A. Letts, Barbara J. Beyer, and Wayne N. Frankel
Dendritic cell-based therapeutic vaccine elicits polyfunctional HIV-specific T-cell immunity associated with control of viral load., Yves Lévy, Rodolphe Thiébaut, Monica Montes, Christine Lacabaratz, Louis Sloan, Bryan King, Sophie Pérusat, Carson Harrod, Amanda Cobb, Lee K Roberts, Mathieu Surenaud, Céline Boucherie, Sandra Zurawski, Constance Delaugerre, Laura Richert, Geneviève Chêne, Jacques Banchereau, and Karolina Palucka
Genetic modulation of nephrocalcinosis in mouse models of ectopic mineralization: the Abcc6(tm1Jfk) and Enpp1(asj) mutant mice., Qiaoli Li, David W Chou, Thea P Price, John P. Sundberg, and Jouni Uitto
Mouse models for pseudoxanthoma elasticum: genetic and dietary modulation of the ectopic mineralization phenotypes., Qiaoli Li, Haitao Guo, David W Chou, Annerose Berndt, John P. Sundberg, and Jouni Uitto
Spontaneous asj-2J Mutant Mouse as a Model for Generalized Arterial Calcification of Infancy: A Large Deletion/Insertion Mutation in the Enpp1 Gene., Qiaoli Li, C Herbert Pratt, Louise A. Dionne, Heather Fairfield, Son Yong Karst, John P. Sundberg, and Jouni Uitto
Juxta-articular joint-capsule mineralization in CD73 deficient mice: Similarities to patients with NT5E mutations., Qiaoli Li, Thea P Price, John P. Sundberg, and Jouni Uitto
High-resolution sex-specific linkage maps of the mouse reveal polarized distribution of crossovers in male germline., Eric Yi Liu, Andrew P Morgan, Elissa J. Chesler, Wei Wang, Gary Churchill, and Fernando Pardo-Manuel de Villena
Interrogating congenital heart defects with noninvasive fetal echocardiography in a mouse forward genetic screen., Xiaoqin Liu, Richard Francis, Andrew J Kim, Ricardo Ramirez, Guozhen Chen, Ramiah Subramanian, Shane Anderton, Youngsil Kim, Liyin Wong, Judy Morgan, Herbert C. Pratt, Laura G. Reinholdt, William Devine, Linda Leatherbury, Kimimasa Tobita, and Cecilia W Lo
Deficiencies in tRNA synthetase editing activity cause cardioproteinopathy., Ye Liu, Jakob S Satz, My-Nuong Vo, Leslie A Nangle, Paul Schimmel, and Susan L. Ackerman
Choline kinase beta is required for normal endochondral bone formation., Zhuo Li, Gengshu Wu, Roger B Sher, Zohreh Khavandgar, Martin Hermansson, Gregory A. Cox, Michael R Doschak, Monzur Murshed, Frank Beier, and Dennis E Vance
Molecular pathogenesis of congenital diaphragmatic hernia revealed by exome sequencing, developmental data, and bioinformatics., Mauro Longoni, Frances A High, Meaghan K Russell, Alireza Kashani, Adam A Tracy, Caroline M Coletti, Regis Hila, Ahmed Shamia, Julie Wells, Kate G Ackerman, Jay M Wilson, Carol J. Bult, Charles Lee, Kasper Lage, Barbara R Pober, and Patricia K Donahoe
Correction of the Crb1rd8 Allele and Retinal Phenotype in C57BL/6N Mice Via TALEN-Mediated Homology-Directed Repair., Benjamin E. Low, Mark P. Krebs, J Keith Joung, Shengdar Q Tsai, Patsy M. Nishina, and Michael V. Wiles
Optimizing mouse models of neurodegenerative disorders: are therapeutics in sight?, Cathleen Lutz and Melissa Osborne
Direct Evidence for Pitavastatin Induced Chromatin Structure Change in the KLF4 Gene in Endothelial Cells., Takashi Maejima, Tsuyoshi Inoue, Yasuharu Kanki, Takahide Kohro, Guoliang Li, Yoshihiro Ohta, Hiroshi Kimura, Mika Kobayashi, Akashi Taguchi, Shuichi Tsutsumi, Hiroko Iwanari, Shogo Yamamoto, Hirofumi Aruga, Shoulian Dong, Junko F Stevens, Huay Mei Poh, Kazuki Yamamoto, Takeshi Kawamura, Imari Mimura, Jun-Ichi Suehiro, Akira Sugiyama, Kiyomi Kaneki, Haruki Shibata, Yasunobu Yoshinaka, Takeshi Doi, Akimune Asanuma, Sohei Tanabe, Toshiya Tanaka, Takashi Minami, Takao Hamakubo, Juro Sakai, Naohito Nozaki, Hiroyuki Aburatani, Masaomi Nangaku, Xiaoan Ruan, Hideyuki Tanabe, Yijun Ruan, Sigeo Ihara, Akira Endo, Tatsuhiko Kodama, and Youichiro Wada
Basis for enhanced barrier function of pigmented skin., Mao-Qiang Man, Tzu-Kai Lin, Juan L Santiago, Anna Celli, Lily Zhong, Zhi-Ming Huang, Truus Roelandt, Melanie Hupe, John P. Sundberg, Kathleen A. Silva, Debra Crumrine, Gemma Martin-Ezquerra, Carles Trullas, Richard Sun, Joan S Wakefield, Maria L Wei, Kenneth R Feingold, Theodora M Mauro, and Peter M Elias
A topological similarity measure for proteins., Gabriell Máté, Andreas Hofmann, Nicolas Wenzel, and Dieter W Heermann
NOD-scidIl2rg (tm1Wjl) and NOD-Rag1 (null) Il2rg (tm1Wjl) : A Model for Stromal Cell-Tumor Cell Interaction for Human Colon Cancer., Justin Maykel, Jian Hua Liu, Hanchen Li, Leonard D. Shultz, Dale L Greiner, and JeanMarie Houghton
Ultrasmall integrated 3D micro-supercapacitors solve energy storage for miniature devices., Chuizhou Meng, Jimin Maeng, Simon W M John, and Pedro P. Irazoqui
DNA methylation dynamics during epigenetic reprogramming in the germline and preimplantation embryos., Daniel M Messerschmidt, Barbara B. Knowles, and Davor Solter
Rapamycin-mediated lifespan increase in mice is dose and sex dependent and metabolically distinct from dietary restriction., Richard A Miller, David E. Harrison, Clinton M. Astle, Elizabeth Fernandez, Kevin Flurkey, Melissa Han, Martin A Javors, Xinna Li, Nancy L Nadon, James F Nelson, Scott Pletcher, Adam B Salmon, Zelton Dave Sharp, Sabrina Van Roekel, Lynn Winkleman, and Randy Strong
The antipsychotic olanzapine interacts with the gut microbiome to cause weight gain in mouse., Andrew P Morgan, James J Crowley, Randal J Nonneman, Corey R Quackenbush, Cheryl N Miller, Allison K Ryan, Molly A. Bogue, Sur Herrera Paredes, Scott Yourstone, Ian M Carroll, Thomas H Kawula, Maureen A Bower, R Balfour Sartor, and Patrick F Sullivan
Effects of housing density in five inbred strains of mice., Judy Morgan, Karen L. Svenson, Jeffrey P Lake, Weidong Zhang, Timothy M. Stearns, Michael A. Marion, Luanne L. Peters, Beverly J. Paigen, and Leah Rae Donahue
Differential roles of epigenetic changes and Foxp3 expression in regulatory T cell-specific transcriptional regulation., Hiromasa Morikawa, Naganari Ohkura, Alexis Vandenbon, Masayoshi Itoh, Sayaka Nagao-Sato, Hideya Kawaji, Timo Lassmann, Piero Carninci, Yoshihide Hayashizaki, Alistair R R Forrest, Daron M Standley, Hiroshi Date, Shimon Sakaguchi, and FANTOM Consortium
Variation and Genetic Control of Gene Expression in Primary Immunocytes across Inbred Mouse Strains., Sara Mostafavi, Adriana Ortiz-Lopez, Molly A. Bogue, Kimie Hattori, Cristina Pop, Daphne Koller, Diane Mathis, Christophe Benoist, David A Blair, Michael L Dustin, Susan A Shinton, Richard R Hardy, Tal Shay, Aviv Regev, Nadia Cohen, Patrick Brennan, Michael Brenner, Francis Kim, Tata Nageswara Rao, Amy Wagers, Tracy Heng, Jeffrey Ericson, Katherine Rothamel, Adriana Ortiz-Lopez, Diane Mathis, Christophe Benoist, Taras Kreslavsky, Anne Fletcher, Kutlu Elpek, Angelique Bellemare-Pelletier, Deepali Malhotra, Shannon Turley, Jennifer Miller, Brian Brown, Miriam Merad, Emmanuel L Gautier, Claudia Jakubzick, Gwendalyn J Randolph, Paul Monach, Adam J Best, Jamie Knell, Ananda Goldrath, Vladimir Jojic, Daphne Koller, David Laidlaw, Jim Collins, Roi Gazit, Derrick J Rossi, Nidhi Malhotra, Katelyn Sylvia, Joonsoo Kang, Natalie A Bezman, Joseph C Sun, Gundula Min-Oo, Charlie C Kim, and Lewis L Lanier
RNA-Seq Alignment to Individualized Genomes Improves Transcript Abundance Estimates in Multiparent Populations., Steven C. Munger, Narayanan Raghupathy, Kwangbom Choi, Allen K. Simons, Daniel Mario Gatti, Douglas Hinerfeld, Karen L. Svenson, Mark P Keller, Alan D Attie, Matthew A. Hibbs, Joel H. Graber, Elissa J. Chesler, and Gary Churchill
Spontaneous CNV in a Novel Mutant Mouse Is Associated With Early VEGF-A-Driven Angiogenesis and Late-Stage Focal Edema, Neural Cell Loss, and Dysfunction., Norihiro Nagai, Pete Lundh von Leithner, Kanako Izumi-Nagai, Brett Hosking, Bo Chang, Ronald E. Hurd, Peter Adamson, Anthony P Adamis, Richard H Foxton, Yin Shan Ng, and David T Shima
Determining immune components necessary for progression of pigment dispersing disease to glaucoma in DBA/2J mice., K Saidas Nair, Jessica Barbay, Richard Smith, Sharmila Masli, and Simon W M John
Protein Ontology: a controlled structured network of protein entities., Darren A Natale, Cecilia N Arighi, Judith A. Blake, Carol J. Bult, Karen R. Christie, Julie Cowart, Peter D'Eustachio, Alexander D Diehl, Harold J. Drabkin, Olivia Helfer, Hongzhan Huang, Anna Maria Masci, Jia Ren, Natalia V Roberts, Karen Ross, Alan Ruttenberg, Veronica Shamovsky, Barry Smith, Meher Shruti Yerramalla, Jian Zhang, Aisha Aljanahi, Irem Celen, Cynthia Gan, Mengxi Lv, Emily Schuster-Lezell, and Cathy H Wu
Modes and regulation of endocytic membrane retrieval in mouse auditory hair cells., Jakob Neef, Sangyong Jung, Aaron B Wong, Kirsten Reuter, Tina Pangrsic, Rituparna Chakrabarti, Sebastian Kügler, Christine Lenz, Régis Nouvian, Rebecca M. Boumil, Wayne N. Frankel, Carolin Wichmann, and Tobias Moser
The PAX2-null immunophenotype defines multiple lineages with common expression signatures in benign and neoplastic oviductal epithelium., Gang Ning, Jonathan G Bijron, Yusuke Yamamoto, Xia Wang, Brooke E Howitt, Michael Herfs, Eric Yang, Yue Hong, Maxence Cornille, Lingyan Wu, Suchanan Hanamornroongruang, Frank D. McKeon, Christopher P Crum, and Wa Xian
ABCC5, a Gene That Influences the Anterior Chamber Depth, Is Associated with Primary Angle Closure Glaucoma., Monisha E Nongpiur, Chiea Chuen Khor, Hongyan Jia, Belinda K Cornes, Li-Jia Chen, Chunyan Qiao, K Saidas Nair, Ching-Yu Cheng, Liang Xu, Ronnie George, Do Tan, Khaled Abu-Amero, Shamira A Perera, Mineo Ozaki, Takanori Mizoguchi, Yasuo Kurimoto, Sancy Low, Liza-Sharmini A Tajudin, Ching-Lin Ho, Clement C Y Tham, Ileana Soto, Paul T K Chew, Hon-Tym Wong, Balekudaru Shantha, Masako Kuroda, Essam A Osman, Guangxian Tang, Sujie Fan, Hailin Meng, Hua Wang, Bo Feng, Victor H K Yong, Serena M L Ting, Yang Li, Ya-Xing Wang, Zheng Li, Raghavan Lavanya, Ren-Yi Wu, Ying-Feng Zheng, Daniel H Su, Seng-Chee Loon, R Rand Allingham, Michael A Hauser, Nagaswamy Soumittra, Vedam L Ramprasad, Naushin Waseem, Azhany Yaakub, Kee-Seng Chia, Govindasamy Kumaramanickavel, Tina T Wong, Alicia C How, Tran Nguyen Bich Chau, Cameron P Simmons, Jin-Xin Bei, Yi-Xin Zeng, Shomi S Bhattacharya, Mingzhi Zhang, Donald T Tan, Yik-Ying Teo, Saleh A Al-Obeidan, Do Nhu Hon, E-Shyong Tai, Seang-Mei Saw, Paul J Foster, Lingam Vijaya, Jost B Jonas, Tien-Yin Wong, Simon W M John, Chi-Pui Pang, Eranga N Vithana, Ningli Wang, and Tin Aung
Genetic analysis of intracapillary glomerular lipoprotein deposits in aging mice., Gerda A Noordmans, Yuan Huang, Holly S. Savage, Marcory C R F van Dijk, Gert Schaart, Marius A van den Bergh Weerman, Peter Heeringa, Jan-Luuk Hillebrands, Ron Korstanje, and Harry van Goor
Physiological and genetic analysis of multiple sodium channel variants in a model of genetic absence epilepsy., M K Oliva, Tracy C. McGarr, Barbara Beyer, E Gazina, D I Kaplan, L Cordeiro, E Thomas, S D Dib-Hajj, S G Waxman, Wayne N. Frankel, and S Petrou
Quantitative trait loci that modulate trabecular bone's risk of failure during unloading and reloading., Engin Ozcivici, Weidong Zhang, Leah Rae Donahue, and Stefan Judex
The effect of culling on health and physiology of mouse litters., Beverly Paigen, Michael A Marion, Timothy M. Stearns, James M Harper, and Karen L. Svenson
SnapShot: Cancer Vaccines., Karolina Palucka and Jacques Banchereau
Microbial sequencing to improve individual and population health., Sharon J Peacock and George M. Weinstock
Amino Acid 72 of Mouse and Human GDF9 Mature Domain Is Responsible for Altered Homodimer Bioactivities but Has Subtle Effects on GDF9:BMP15 Heterodimer Activities., Jia Peng, Karen Wigglesworth, Adithya Rangarajan, John J. Eppig, Thomas B Thompson, and Martin M Matzuk
Dissection of complex gene expression using the combined analysis of pleiotropy and epistasis., Vivek M. Philip, Anna L. Tyler, and Gregory W. Carter
Chronic Proliferative Dermatitis in Sharpin Null Mice: Development of an Autoinflammatory Disease in the Absence of B and T Lymphocytes and IL4/IL13 Signaling., Christopher S. Potter, Zhe Wang, Kathleen A. Silva, Victoria E. Kennedy, Timothy M. Stearns, Lisa Burzenski, Leonard D. Shultz, Harm Hogenesch, and John O. Sundberg
Expression of Neonatal Fc Receptor in the eye., Michael B Powner, Jenny A G McKenzie, Gregory J. Christianson, Derry C. Roopenian, and Marcus Fruttiger
Humanized FcRn mouse models for evaluating pharmacokinetics of human IgG antibodies., Gabriele Proetzel and Derry C. Roopenian
Genetically engineered humanized mouse models for preclinical antibody studies., Gabriele Proetzel, Michael V. Wiles, and Derry C. Roopenian
B Cell Super-Enhancers and Regulatory Clusters Recruit AID Tumorigenic Activity., Jason Qian, Qiao Wang, Marei Dose, Nathanael Pruett, Kyong-Rim Kieffer-Kwon, Wolfgang Resch, Genqing Liang, Zhonghui Tang, Ewy Mathé, Christopher Benner, Wendy Dubois, Steevenson Nelson, Laura Vian, Thiago Y Oliveira, Mila Jankovic, Ofir Hakim, Anna Gazumyan, Rushad Pavri, Parirokh Awasthi, Bin Song, Geng Liu, Longyun Chen, Shida Zhu, Lionel Feigenbaum, Louis Staudt, Cornelis Murre, Yijun Ruan, Davide F Robbiani, Qiang Pan-Hammarström, Michel C Nussenzweig, and Rafael Casellas
Rapid identification of major-effect genes using the collaborative cross., Ramesh Ram, Munish Mehta, Lois Balmer, Daniel Mario Gatti, and Grant Morahan
Precise genetic mapping and integrative bioinformatics in Diversity Outbred mice reveals Hydin as a novel pain gene., Jill M. Recla, Ray F. Robledo, Daniel M. Gatti, Carol J. Bult, Gary A. Churchill, and Elissa J. Chesler
Rapamycin Ameliorates Nephropathy despite Elevating Hyperglycemia in a Polygenic Mouse Model of Type 2 Diabetes, NONcNZO10/LtJ., Peter C. Reifsnyder, Rosalinda A. Doty, and David E. Harrison
Launch of the new letter category: 'Mouse Mutants with Absent/Minimal Skin Phenotype'., Michael Rendl, John P. Sundberg, John Seykora, Thomas Luger, Ralf Paus, and Thomas Trier-Mork
c-Myc inhibition prevents leukemia initiation in mice and impairs the growth of relapsed and induction failure pediatric T-ALL cells., Justine E Roderick, Jessica Tesell, Leonard D. Shultz, Michael A Brehm, Dale L Greiner, Marian H Harris, Lewis B Silverman, Stephen E Sallan, Alejandro Gutierrez, A Thomas Look, Jun Qi, James E Bradner, and Michelle A Kelliher
IFN priming is necessary but not sufficient to turn on a migratory dendritic cell program in lupus monocytes., Alicia Rodriguez-Pla, Pinakeen Patel, Holden T Maecker, Jose Rossello-Urgell, Nicole Baldwin, Lynda Bennett, Victoria Cantrell, Jeanine Baisch, Marilynn Punaro, Alisa Gotte, Lorien Nassi, Tracey Wright, Anna Karolina Palucka, Jacques Banchereau, and Virginia Pascual
OTX2 loss causes rod differentiation defect in CRX-associated congenital blindness., Jerome E Roger, Avinash Hiriyanna, Norimoto Gotoh, Hong Hao, Debbie F Cheng, Rinki Ratnapriya, Marie-Audrey I Kautzmann, Bo Chang, and Anand Swaroop
Development and function of human innate immune cells in a humanized mouse model., Anthony Rongvaux, Tim Willinger, Jan Martinek, Till Strowig, Sofia V Gearty, Lino L Teichmann, Yasuyuki Saito, Florentina Marches, Stephanie Halene, A Karolina Palucka, Markus G Manz, and Richard A Flavell
A methods paper that led to much more., Derry C. Roopenian
Genetic regulation of Zfp30, CXCL1, and neutrophilic inflammation in murine lung., Holly Rutledge, David L Aylor, Danielle E Carpenter, Bailey C Peck, Peter Chines, Lawrence E Ostrowski, Elissa J. Chesler, Gary Churchill, Fernando Pardo-Manuel de Villena, and Samir N P Kelada
CLIC5 stabilizes membrane-actin filament linkages at the base of hair cell stereocilia in a molecular complex with radixin, taperin, and myosin VI., Felipe T Salles, Leonardo R Andrade, Soichi Tanda, M'hamed Grati, Kathleen L Plona, Leona H. Gagnon, Kenneth R. Johnson, Bechara Kachar, and Mark A Berryman
Dissection of the Neonatal Fc Receptor (FcRn)-Albumin Interface Using Mutagenesis and Anti-FcRn Albumin-blocking Antibodies., Kine Marita Knudsen Sand, Bjørn Dalhus, Gregory J. Christianson, Malin Bern, Stian Foss, Jason Cameron, Darrell Sleep, Magnar Bjørås, Derry C. Roopenian, Inger Sandlie, and Jan Terje Andersen
The cytokine TGF-β co-opts signaling via STAT3-STAT4 to promote the differentiation of human TFH cells., Nathalie Schmitt, Yang Liu, Salah-Eddine Bentebibel, Indira Munagala, Laure Bourdery, K Venuprasad, Jacques Banchereau, and Hideki Ueno
Lack of neuropathy-related phenotypes in hint1 knockout mice., Kevin L. Seburn, Kathryn H. Morelli, Albena Jordanova, and Robert W. Burgess
Mutations in Alström protein impair terminal differentiation of cardiomyocytes., Lincoln T Shenje, Peter Andersen, Marc K Halushka, Cecillia Lui, Laviel Fernandez, Gayle B. Collin, Nuria Amat-Alarcon, Wendy Meschino, Ernest Cutz, Kenneth Chang, Raluca Yonescu, Denise A S Batista, Yan Chen, Stephen Chelko, Jane E Crosson, Janet Scheel, Luca Vricella, Brian D Craig, Beth A Marosy, David W Mohr, Kurt N Hetrick, Jane M Romm, Alan F Scott, David Valle, Juergen K. Naggert, Chulan Kwon, Kimberly F Doheny, and Daniel P Judge
A major QTL on mouse chromosome 17 resulting in lifespan variability in SOD1-G93A transgenic mouse models of amyotrophic lateral sclerosis., Roger B Sher, Terry D Heiman-Patterson, Elizabeth A Blankenhorn, Juliann Jiang, Guillermo Alexander, Jeffrey S Deitch, and Gregory A. Cox
Human cancer growth and therapy in immunodeficient mouse models., Leonard D. Shultz, Neal Goodwin, Fumihiko Ishikawa, Vishnu Hosur, Bonnie L. Lyons, and Dale L Greiner
Subcapsular transplantation of tissue in the kidney., Leonard D. Shultz, Neal Goodwin, Fumihiko Ishikawa, Vishnu Hosur, Bonnie L. Lyons, and Dale L Greiner
Systematic Evaluation of the Skin and Adnexa in Mutant Laboratory Mice., Kathleen A. Silva, Victoria E. Kennedy, and John P. Sundberg
Dissection of Immune Gene Networks in Primary Melanoma Tumors Critical for Antitumor Surveillance of Patients with Stage II-III Resectable Disease., Shanthi Sivendran, Rui Chang, Lisa Pham, Robert G Phelps, Sara T Harcharik, Lawrence D Hall, Sebastian G Bernardo, Marina M Moskalenko, Meera Sivendran, Yichun Fu, Ellen H de Moll, Michael Pan, Jee Young Moon, Sonali Arora, Ariella Cohain, Analisa DiFeo, Tammie C Ferringer, Mikhail Tismenetsky, Cindy L Tsui, Philip A Friedlander, Michael K Parides, Jacques Banchereau, Damien Chaussabel, Mark G Lebwohl, Jedd D Wolchok, Nina Bhardwaj, Steven J Burakoff, William K Oh, Karolina Palucka, Miriam Merad, Eric E Schadt, and Yvonne M Saenger
Morphological analysis of neuromuscular junction development and degeneration in rodent lumbrical muscles., James N Sleigh, Robert W. Burgess, Thomas H Gillingwater, and M Zameel Cader
Neuromuscular junction maturation defects precede impaired lower motor neuron connectivity in Charcot-Marie-Tooth type 2D mice., James N Sleigh, Stuart J Grice, Robert W. Burgess, Kevin Talbot, and M Zameel Cader
High-resolution genetic mapping in the diversity outbred mouse population identifies apobec1 as a candidate gene for atherosclerosis., Tangi L Smallwood, Daniel M Gatti, Pamela Quizon, George M. Weinstock, Kuo-Chen Jung, Liyang Zhao, Kunjie Hua, Daniel Pomp, and Brian J Bennett
The mouse Gene Expression Database (GXD): 2014 update., Constance M. Smith, Jacqueline H. Finger, Terry F. Hayamizu, Ingeborg J. McCright, Jingxia Xu, Joanne Berghout, Jeff Campbell, Lori E. Corbani, Kim L. Forthofer, Pete J. Frost, Dave Miers, David R. Shaw, Kevin R. Stone, Janan T. Eppig, James A. Kadin, Joel E. Richardson, and Martin Ringwald
The gene expression database for mouse development (GXD): Putting developmental expression information at your fingertips., Constance M. Smith, Jacqueline H. Finger, James A. Kadin, Joel E. Richardson, and Martin Ringwald
Mutant phenotype analysis suggests potential roles for C-type natriuretic peptide receptor (NPR-B) in male mouse fertility., Chizuru Sogawa, Yasuhiro Fujiwara, Satoshi Tsukamoto, Yuka Ishida, Yukie Yoshii, Takako Furukawa, Tetsuo Kunieda, and Tsuneo Saga
CcpA Is Important for Growth and Virulence of Enterococcus faecium., Sudha R Somarajan, Jung H Roh, Kavindra V Singh, George M. Weinstock, and Barbara E Murray
A murine rp1 missense mutation causes protein mislocalization and slowly progressive photoreceptor degeneration., Delu Song, Steve Grieco, Yafeng Li, Allan Hunter, Sally Chu, Liangliang Zhao, Ying Song, Robert A DeAngelis, Lan-Ying Shi, Qin Liu, Eric A Pierce, Patsy M. Nishina, John D Lambris, and Joshua L Dunaief
The Complex Role of Neuroinflammation in Glaucoma., Ileana Soto and Gareth R. Howell
DBA/2J Mice Are Susceptible to Diabetic Nephropathy and Diabetic Exacerbation of IOP Elevation., Ileana Soto, Gareth R. Howell, Cai W John, Joseph L Kief, Richard T Libby, and Simon W M John
Gene Profiling of Postnatal Mfrprd6 Mutant Eyes Reveals Differential Accumulation of Prss56, Visual Cycle and Phototransduction mRNAs., Ramani Soundararajan, Jungyeon Won, Timothy M. Stearns, Jeremy R. Charette, Wanda L. Hicks, Gayle B. Collin, Juergen K. Naggert, Mark P. Krebs, and Patsy M. Nishina
Molecular identification of collagen 17a1 as a major genetic modifier of laminin gamma 2 mutation-induced junctional epidermolysis bullosa in mice., Thomas J. Sproule, Jason A. Bubier, Fiorella C Grandi, Victor Z Sun, Vivek M. Philip, Caroline G. McPhee, Elisabeth B. Adkins, John P. Sundberg, and Derry C. Roopenian
Discovery of transgene insertion sites by high throughput sequencing of mate pair libraries., Anuj Srivastava, Vivek M. Philip, Ian Greenstein, Lucy B. Rowe, Mary Barter, Cathleen Lutz, and Laura G Reinholdt
Immunohistochemical analysis of metaplastic non-goblet columnar lined oesophagus shows phenotypic similarities to Barrett's oesophagus: A study in an Asian population., Supriya Srivastava, Mei Shan Liew, Frank D. McKeon, Wa Xian, Khay Guan Yeoh, Khek Yu Ho, and Ming Teh
Unc5C and DCC act downstream of Ctip2 and Satb2 and contribute to corpus callosum formation., Swathi Srivatsa, Srinivas Parthasarathy, Olga Britanova, Ingo Bormuth, Amber-Lee Donahoo, Susan L. Ackerman, Linda J Richards, and Victor Tarabykin
Whole Genome Sequence of the Treponema pallidum subsp. endemicum Strain Bosnia A: The Genome Is Related to Yaws Treponemes but Contains Few Loci Similar to Syphilis Treponemes., Barbora Staudová, Michal Strouhal, Marie Zobaníková, Darina Cejková, Lucinda L Fulton, Lei Chen, Lorenzo Giacani, Arturo Centurion-Lara, Sylvia M Bruisten, Erica Sodergren, George M. Weinstock, and David Smajs
A Dominant Mutation in Hexokinase 1 (HK1) Causes Retinitis Pigmentosa., Lori S Sullivan, Daniel C Koboldt, Sara J Bowne, Steven Lang, Susan H Blanton, Elizabeth Cadena, Cheryl E Avery, Richard A Lewis, Kaylie Webb-Jones, Dianna H Wheaton, David G Birch, Razck Coussa, Huanan Ren, Irma Lopez, Christina Chakarova, Robert K Koenekoop, Charles A Garcia, Robert S Fulton, Richard K Wilson, George M. Weinstock, and Stephen P Daiger
Crisp1 and alopecia areata in C3H/HeJ mice., John P. Sundberg, Alexander Awgulewitsch, Nathan D Pruett, Christopher S Potter, Kathleen A Silva, Timothy M Stearns, Beth A. Sundberg, Mariana Weigel Muñoz, Patricia S Cuasnicu, Lloyd E King, and Robert H Rice
Mouse alopecia areata and heart disease: know your mouse!, John P. Sundberg, Lucie Chevallier, Kathleen A. Silva, Victoria E. Kennedy, Beth A. Sundberg, Qiaoli Li, Jouni Uitto, Lloyd E King, and Annerose Berndt
Immune Status, Strain Background, and Anatomic Site of Inoculation Affect Mouse Papillomavirus (MmuPV1) Induction of Exophytic Papillomas or Endophytic Trichoblastomas., John P. Sundberg, Timothy M. Stearns, Joongho Joh, Mary Proctor, Arvind Ingle, Kathleen A. Silva, Soheil S Dadras, A Bennett Jenson, and Shin-Je Ghim
The MuSK activator agrin has a separate role essential for postnatal maintenance of neuromuscular synapses., Tohru Tezuka, Akane Inoue, Taisuke Hoshi, Scott D Weatherbee, Robert W. Burgess, Ryo Ueta, and Yuji Yamanashi
Detecting and characterizing pleiotropy: new methods for uncovering the connection between the complexity of genomic architecture and multiple phenotypes- session introduction., Anna L. Tyler, Dana C Crawford, and Sarah A Pendergrass
A genetic interaction network model of a complex neurological disease., Anna L. Tyler, Tracy C. McGarr, Barbara Beyer, Wayne N. Frankel, and Gregory W. Carter
Detection of chromosomal breakpoints in patients with developmental delay and speech disorders., Kagistia H Utami, Axel M Hillmer, Irene Aksoy, Elaine G Y Chew, Audrey S M Teo, Zhenshui Zhang, Charlie W H Lee, Pauline J Chen, Chan Chee Seng, Pramila N Ariyaratne, Sigrid L Rouam, Lim Seong Soo, Saira Yousoof, Ivan Prokudin, Gregory Peters, Felicity Collins, Meredith Wilson, Alyson Kakakios, Georges Haddad, Arnaud Menuet, Olivier Perche, Stacey Kiat Hong Tay, Ken W K Sung, Xiaoan Ruan, Yijun Ruan, Edison Liu, Sylvain Briault, Robyn V Jamieson, Sonia Davila, and Valere Cacheux
Steady state analysis of Boolean molecular network models via model reduction and computational algebra., Alan Veliz-Cuba, Boris Aguilar, Franziska Hinkelmann, and Reinhard Laubenbacher
An algebra-based method for inferring gene regulatory networks., Paola Vera-Licona, Abdul Jarrah, Luis David Garcia-Puente, John McGee, and Reinhard Laubenbacher
Landscape and variation of RNA secondary structure across the human transcriptome., Yue Wan, Kun Qu, Qiangfeng Cliff Zhang, Ryan A Flynn, Ohad Manor, Zhengqing Ouyang, Jiajing Zhang, Robert C Spitale, Michael P Snyder, Eran Segal, and Howard Y Chang
Next-generation pathogen genomics., George M. Weinstock and Sharon J Peacock
Metabolomics as a tool for discovery of biomarkers of autism spectrum disorder in the blood plasma of children., Paul R West, David G Amaral, Preeti Bais, Alan M Smith, Laura A Egnash, Mark E Ross, Jessica A Palmer, Burr R Fontaine, Kevin R Conard, Blythe A Corbett, Gabriela G Cezar, Elizabeth L R Donley, and Robert E Burrier
DFLAT: functional annotation for human development., Heather C Wick, Harold J. Drabkin, Huy Ngu, Michael Sackman, Craig Fournier, Jessica Haggett, Judith A. Blake, Diana W Bianchi, and Donna K Slonim