Submissions from 2025
RNA binding of GAPDH controls transcript stability and protein translation in acute myeloid leukemia., Sama Shamloo, Jeffrey L Schloßhauer, Shashank Tiwari, Kim Denise Fischer, Omar Almolla, Yohana Ghebrechristos, Lisa Kratzenberg, Aathma Merin Bejoy, Ioannis Aifantis, Francesco Boccalatte, Eric Wang, and Jochen Imig
Structures of ATP-binding cassette transporter ABCC1 reveal the molecular basis of cyclic dinucleotide cGAMP export., Omkar Shinde, Joshua A Boyer, Stephanie Cambier, Jordyn J VanPortfliet, Xuewu Sui, Gaya P Yadav, Elizabeth G Viverette, Mario J Borgnia, A Phillip West, Qi Zhang, Daniel B Stetson, and Pingwei Li
High-Throughput Echocardiography-Guided Induction of Myocardial Ischemia/Reperfusion in Mice., Florian Sicklinger, Niklas Hartmann, Attila Kovacs, Carla Weinheimer, Jess Nigro, Tobias Thiemann, Junedh M Amrute, David Schumacher, Moritz P Kornadt, Laura M Wienecke, Lennart Rompel, Johannes Fischer, John F Bachman, Olivia Bedard, Shibali Das, Tim C Kuhn, Mirko Völkers, Ralf P Brandes, Rafael Kramann, Nadia Rosenthal, Norbert Frey, Kory J Lavine, and Florian Leuschner
Oncopacket: integration of cancer research data using GA4GH phenopackets., Michael Sierk, Daniel Danis, Sujay Patil, Nobal Kishor, Rajdeep Mondal, Abhishek Jha, Qingrong Chen, Chunhua Yan, Monica Munoz-Torres, Daoud Meerzaman, Peter N Robinson, and Justin T Reese
Mapping the genetic landscape establishing a tumor immune microenvironment favorable for anti-PD-1 response., Daniel A Skelly, John P Graham, Mingshan Cheng, Mayuko Furuta, Andrew Walter, Thomas A Stoklasek, Hongyuan Yang, Timothy M Stearns, Olivier Poirion, Ji-Gang Zhang, Jessica D S Grassmann, Diane Luo, William F Flynn, Elise T Courtois, Chih-Hao Chang, David V. Serreze, Francesca Menghi, Laura G Reinholdt, and Edison Liu
In vivo prime editing rescues alternating hemiplegia of childhood in mice., Alexander A Sousa, Markus Terrey, Holt A Sakai, Christine Q Simmons, Elena Arystarkhova, Natalia S Morsci, Laura C. Anderson, Jun Xie, Fabian Suri-Payer, Linda C Laux, Emmanuel Roze, Sylvie Forlani, Guangping Gao, Simon Frost, Nina Frost, Kathleen J Sweadner, Alfred L George, Cathleen Lutz, and David R Liu
Pluripotent cell states and fates in human embryo models., Berna Sozen, Patrick P L Tam, and Martin Pera
Deciphering the longitudinal trajectories of glioblastoma ecosystems by integrative single-cell genomics., Avishay Spitzer, Kevin C Johnson, Masashi Nomura, Luciano Garofano, Djamel Nehar-Belaid, Noam Galili Darnell, Alissa C Greenwald, Lillian Bussema, Young Taek Oh, Frederick S Varn, Fulvio D'Angelo, Simon Gritsch, Kevin J Anderson, Simona Migliozzi, L Nicolas Gonzalez Castro, Tamrin Chowdhury, Nicolas Robine, Catherine Reeves, Jong Bae Park, Anuja Lipsa, Frank Hertel, Anna Golebiewska, Simone P Niclou, Labeeba Nusrat, Sorcha Kellet, Sunit Das, Hyo-Eun Moon, Sun Ha Paek, Franck Bielle, Alice Laurenge, Anna Luisa Di Stefano, Bertrand Mathon, Alberto Picca, Marc Sanson, Shota Tanaka, Nobuhito Saito, David M Ashley, Stephen T Keir, Keith L Ligon, Jason T Huse, W K Alfred Yung, Anna Lasorella, Antonio Iavarone, Roel G W Verhaak, Itay Tirosh, and Mario L Suvà
Your Blood is Out for Delivery: Considerations of Shipping Time and Temperature on Degradation of RNA from Stabilized Whole Blood., Filip Stefanovic, Lauren G Brown, James MacDonald, Theo Bammler, Darawan Rinchai, Serena Nguyen, Yuting Zeng, Victoria Shinkawa, Karen Adams, Damien Chaussabel, Erwin Berthier, Amanda J Haack, and Ashleigh B Theberge
Extravillous trophoblasts reverse the decidualization induced increase in matrix production by secreting TGFβ antagonists Emilin-1 and Gremlin-1., Yasir Suhail, Yamin Liu, Junaid Afzal, Wenqiang Du, Paul Robson, Ashkan Novin, Ramalakshmi Ramasamy, and Kshitiz
Multiomic Network Analysis Identifies Dysregulated Neurobiological Pathways in Opioid Addiction., Kyle A Sullivan, David Kainer, Matthew Lane, Mikaela Cashman, J Izaak Miller, Michael R Garvin, Alice Townsend, Bryan C Quach, Caryn Willis, Peter Kruse, Nathan C Gaddis, Ravi Mathur, Olivia Corradin, Brion S Maher, Peter C Scacheri, Sandra Sanchez-Roige, Abraham A Palmer, Vanessa Troiani, Elissa J Chesler, Rachel L Kember, Henry R Kranzler, Amy C Justice, Ke Xu, Bradley E Aouizerat, Dana B Hancock, Eric O Johnson, Daniel A Jacobson, and V. A. Million Veteran Program.
A Multimodal Therapeutic Strategy for Inflammatory Bowel Disease Using MicroRNA-146a Mimic Encapsulated in Lipid Nanoparticles., Kanika Suri, Vishnu Hosur, Rohit Panchakshari, and Mansoor M Amiji
From gene modules to gene markers: an integrated AI-human approach selects CD38 to represent plasma cell-associated transcriptional signatures., Basirudeen Syed Ahamed Kabeer, Bishesh Subba, Darawan Rinchai, Mohammed Toufiq, Taushif Khan, Marina Yurieva, and Damien Chaussabel
A feasibility study of enzymatic methylation sequencing of cell-free DNA from cerebrospinal fluid of pediatric central nervous system tumor patients for molecular classification., Aaron M Taylor, Jody T Lombardi, Areeba Patel, Ariella Tamariz, Jonathan Martin, Markus J Bookland, David S Hersh, Evan Cantor, Xianyuan Song, Felix Sahm, Patrick Ks Ng, Joanna J Gell, and Ching C Lau
Immunosuppressive Tumor Microenvironment of Osteosarcoma., Aaron M Taylor, Jianting Sheng, Patrick Ks Ng, Jeffrey M. Harder, Parveen Kumar, Ju Young Ahn, Yuliang Cao, Alissa M Dzis, Nathaniel L. Jillette, Andrew Goodspeed, Avery Bodlak, Qian Wu, Michael S Isakoff, Joshy George, Jessica D S Grassmann, Diane Luo, William F Flynn, Elise T Courtois, Paul Robson, Masanori Hayashi, Alini Trujillo Paolillo, Antonio Sergio Petrilli, Silvia Regina Caminada de Toledo, Fabiola Sara Balarezo, Adam D Lindsay, Bang Hoang, Stephen T C Wong, and Ching C Lau
Plot twist: TET2 clones save the brain., Maria Telpoukhovskaia and Jennifer J. Trowbridge
Synaptic dysregulation in a mouse model of GRIN2D developmental and epileptic encephalopathy., JiaJie Teoh, Jane Simko, Chad R Camp, Christine J Liu, Wanqi Wang, Damian J Williams, Liang Ma, Divyalakshmi Soundararajan, Caryn Martin, Noah K Taylor, Ekniel François, Sabrina Petri, Ayla Kanber, Aishwarya Ravichandra, Maria Elena Pero, Francesca Bartolini, Theresa C Swayne, Cathleen Lutz, Aamir Zuberi, Moran Rubinstein, Moran Hausman-Kedem, Hongjie Yuan, Jennifer N Gelinas, Tristan T Sands, Scott Q Harper, Stephen F Traynelis, Christopher D Makinson, and Wayne N Frankel
Alternating hemiplegia of childhood associated mutations in Atp1a3 reveal diverse neurological alterations in mice., Markus Terrey, Georgii Krivoshein, Scott I Adamson, Elena Arystarkhova, Laura C. Anderson, John Szwec, Shelby McKee, Holly Jones, Sara Perkins, Vijay Selvam, Pierre-Alexandre Piec, Dweet Chhaya, Ari Dehn, Aamir Zuberi, Stephen A Murray, Natalia S Morsci, Kathleen J Sweadner, David A Knowles, Else A Tolner, Arn M J M van den Maagdenberg, and Cathleen Lutz
Targeting Ion Channels: Blockers Suppress Calcium Signals and Induce Cytotoxicity Across Medulloblastoma Cell Models., Darani Ashley Thammavongsa, Taylor N Jackvony, Markus J Bookland, and Min D Tang-Schomer
Absence of Glaucoma in Tg-MYOCY437H Mice of Diverse Genetic Backgrounds., Nicholas G Tolman, Marina Simón, Felicia A Juarez, Chi Zhang, Zhivka I Hristova, Tionna Ouellette, Michael A Sellarole, Wilhelmine N deVries, Christa Montgomery, and Simon W M John
The integrative genomic and functional immunological analyses of colorectal cancer initiating cells to modulate stemness properties and the susceptibility to immune responses., Issam Tout, Salim Bougarn, Mohammed Toufiq, Neha Gopinath, Ola Hussein, Abbirami Sathappan, Evonne Chin-Smith, Fazulur Rehaman, Rebecca Mathew, Lisa Mathew, Kun Wang, Li Liu, Abdulrahman Salhab, Oleksandr Soloviov, Sara Tomei, Waseem Hasan, Sahar Da'as, Yosra Bejaoui, Nady El Hajj, Karama Makni Maalej, Said Dermime, Kakil Rasul, Paolo Dellabona, Giulia Casorati, Alice Turdo, Matilde Todaro, Giorgio Stassi, Soldano Ferrone, Xinhui Wang, and Cristina Maccalli
Effective integration of multi-omics with prior knowledge to identify biomarkers via explainable graph neural networks., Rohit K Tripathy, Zachary Frohock, Hong Wang, Gregory Cary, Stephen Keegan, Gregory W. Carter, and Yi Li
Transcripts with high distal heritability mediate genetic effects on complex metabolic traits., Anna L. Tyler, J Matthew Mahoney, Mark P Keller, Candice N Baker, Margaret Gaca, Anuj Srivastava, Isabela Gerdes Gyuricza, Madeleine J Braun, Nadia Rosenthal, Alan D Attie, Gary Churchill, and Gregory W. Carter
Metabolomic and lipidomic atlas of human hair across its length., Maria van de Lavoir, Yuanye Chi, Ting Zeng, Rani Robeyns, Maria Del Mar Delgado Povedano, Leen Jacobs, Celine Gys, Hugo Neels, Shuzhao Li, Alexander L N van Nuijs, and Adrian Covaci
Caspase-11 drives macrophage hyperinflammation in models of Polg-related mitochondrial disease., Jordyn J VanPortfliet, Yuanjiu Lei, Muthumeena Ramanathan, Camila Guerra Martinez, Jessica Wong, Tim J Stodola, Brian Hoffmann, Kathryn Pflug, Raquel Sitcheran, Stephen C. Kneeland, Stephen A Murray, Peter J McGuire, Carolyn L Cannon, and A Phillip West
Systematic ocular phenotyping of 8,707 knockout mouse lines identifies genes associated with abnormal corneal phenotypes., Peter Vo, Denise M Imai-Leonard, Benjamin Yang, Andrew Briere, Andy Shao, M Isabel Casanova, David Adams, Takanori Amano, Oana Amarie, Zorana Berberovic, Lynette Bower, Robert E Braun, Steve Brown, Samantha Burrill, Soo Young Cho, Sharon Clementson-Mobbs, Abigail D'Souza, Mary Dickinson, Mohammad Eskandarian, Ann M Flenniken, Helmut Fuchs, Valerie Gailus-Durner, Jason Heaney, Yann Hérault, Martin Hrabe de Angelis, Chih-Wei Hsu, Shundan Jin, Russell Joynson, Yeon Kyung Kang, Haerim Kim, Hiroshi Masuya, Hamid Meziane, Stephen A Murray, Ki-Hoan Nam, Hyuna Noh, Lauryl M J Nutter, Marcela Palkova, Jan Prochazka, Miles Joseph Raishbrook, Fabrice Riet, Jennifer L Ryan, Jason Salazar, Zachery Seavey, John Richard Seavitt, Radislav Sedlacek, Mohammed Selloum, Kyoung Yul Seo, Je Kyung Seong, Hae-Sol Shin, Toshihiko Shiroishi, Michelle Stewart, Karen L. Svenson, Masaru Tamura, Heather Tolentino, Uchechukwu Udensi, Sara Wells, Jacqueline K White, Amelia M Willett, Janine M Wotton, Wolfgang Wurst, Atsushi Yoshiki, Louise Lanoue, K C Kent Lloyd, Brian C Leonard, Michel J Roux, Colin McKerlie, and Ala Moshiri
Retrograde mitochondrial signaling governs the identity and maturity of metabolic tissues., Emily M Walker, Gemma L Pearson, Nathan Lawlor, Ava M Stendahl, Anne Lietzke, Vaibhav Sidarala, Jie Zhu, Tracy Stromer, Emma C Reck, Jin Li, Elena Levi-D'Ancona, Mabelle B Pasmooij, Dre L Hubers, Aaron Renberg, Kawthar Mohamed, Vishal S Parekh, Irina X Zhang, Benjamin Thompson, Deqiang Zhang, Sarah A Ware, Leena Haataja, Nathan Qi, Stephen C J Parker, Peter Arvan, Lei Yin, Brett A Kaufman, Leslie S Satin, Lori Sussel, Michael L. Stitzel, and Scott A Soleimanpour
A comprehensive atlas of AAV tropism in the mouse., Christopher J Walkey, Kathy J. Snow, Jote Bulcha, Aaron R Cox, Alexa E Martinez, M Cecilia Ljungberg, Denise G Lanza, Marco De Giorgi, Marcel A Chuecos, Michele Alves-Bezerra, Carlos Flores Suarez, Sean M Hartig, Susan G Hilsenbeck, Chih-Wei Hsu, Ethan Saville, Yaned Gaitan, Jeff Duryea, Seth Hannigan, Mary E Dickinson, Oleg Mirochnitchenko, Dan Wang, Cathleen Lutz, Jason D Heaney, Guangping Gao, Stephen A Murray, and William R Lagor
Analysis of functional connectivity changes from childhood to old age: A study using HCP-D, HCP-YA, and HCP-A datasets., Yaotian Wang, Shuoran Li, Jie He, Lingyi Peng, Qiaochu Wang, Xu Zou, Dana L Tudorascu, David J Schaeffer, Lauren Schaeffer, Diego Szczupak, Jung Eun Park, Stacey J Sukoff Rizzo, Gregory W. Carter, Afonso C Silva, and Tingting Zhang
Whole-genome sequencing reveals individual and cohort level insights into chromosome 9p syndromes., Yingxi Wang, Eleanor I Sams, Rachel Slaugh, Sandra Crocker, Emily Cordova Hurtado, Sophia Tracy, Ying-Chen Claire Hou, Christopher Markovic, Kostandin Valle, Victoria Tate, Khadija Belhassan, Elizabeth Appelbaum, Titilope Akinwe, Rodrigo T Starosta, Yang Cao, Amber Neilson, Yu Liu, Nathaniel Jensen, Reza Ghasemi, Tina Lindsay, Juana Manuel, Sophia Couteranis, Milinn Kremitzki, Jack Ustanik, Thomas Antonacci, Jeffrey K Ng, Andrew Emory, Laura Metz, Tracie DeLuca, Katherine N Lyons, Toni Sinnwell, Brianne Thomeczek, Kymme Wang, Nick Sisneros, Megha Muraleedharan, Anantha Kethireddy, Marco Corbo, Harsha Gowda, Katherine A King, Christina A Gurnett, Susan K Dutcher, Catherine Gooch, Yang E Li, Matthew W Mitchell, Kevin A Peterson, Amjad Horani, Jill A Rosenfeld, Weimin Bi, Pawel Stankiewicz, Hsiao-Tuan Chao, Jennifer E Posey, Christopher M Grochowski, Zain Dardas, Erik G Puffenberger, Christopher E Pearson, Frank Kooy, Dale Annear, A Micheil Innes, Michael Heinz, Richard Head, Robert Fulton, Stephan Toutain, Lucinda Antonacci-Fulton, Xiaoxia Cui, Robi D Mitra, F Sessions Cole, Julie Neidich, Patricia I Dickson, Jeffrey Milbrandt, and Tychele N Turner
Errors in pathology: The real world., Jerrold M Ward, Jeffrey C Wolf, and John P Sundberg
The CD123 antibody-drug conjugate pivekimab sunirine exerts profound activity in preclinical models of pediatric acute lymphoblastic leukemia., Ben Watts, Christopher M Smith, Kathryn Evans, Andrew J Gifford, Sara M A Mohamed, Stephen W Erickson, Eric J Earley, Steven Neuhauser, Timothy M Stearns, Vivek M. Philip, Jeffrey Chuang, Patrick A Zweidler-McKay, Sribalaji Lakshmikanthan, Emily L Jocoy, Carol J Bult, Beverly A Teicher, Malcolm A Smith, and Richard B Lock
Phenotypic Expansion of Knobloch Syndrome Type 2 in an Individual With a De Novo PAK2 Variant., Elizabeth A Werren, Louisa Kalsner, Jessica M Ewald, Michael Peracchio, Cameron King, Purva Vats, Peter A Audano, Peter N Robinson, Mark D Adams, Melissa A Kelly, and Adam P Matson
Tipping the balance: innate and adaptive immunity in mitochondrial disease., A Phillip West and Peter J McGuire
Low-coverage whole-genome sequencing facilitates accurate and cost-effective haplotype reconstruction in complex mouse crosses., Samuel J Widmayer, Lydia K Wooldridge, Emily Swanzey, Mary Barter, Chrystal M Snow, Michael C Saul, Qingchang Meng, Beth L Dumont, Laura G Reinholdt, and Daniel M Gatti
Identifying genetic determinants of outer retinal function in mice using a large-scale gene-targeted screen., Janine M Wotton, Mark P. Krebs, Riccardo Sangermano, Jessica Wong, Cynthia Smith, Amelia M Willett, Douglas Howell, Abby Jones, Catherine Witmeyer, Jacob P Lowy, Michael McFarland, Stephen A Murray, Robert E Braun, Patsy M. Nishina, Eric A Pierce, Emily M Place, Kinga M Bujakowska, Neal S Peachey, and Jacqueline K White
The HUGO Clinical Genomics & Genomic Medicine Education Survey: clinicians globally need and want genomic medicine training., Charles Wray, Edward S Tobias, Dhavendra Kumar, Qasim Ayub, Ada Hamosh, Iscia Lopes-Cendes, Luz Berenice Lopez Hernandez, and Sherifa Ahmed Hamed
AI-driven multi-omics modeling of myalgic encephalomyelitis/chronic fatigue syndrome., Ruoyun Xiong, Elizabeth Aiken, Ryan Caldwell, Suzanne D Vernon, Lina Kozhaya, Courtney Gunter, Lucinda Bateman, Derya Unutmaz, and Julia Oh
AI-driven multi-omics modeling of myalgic encephalomyelitis/chronic fatigue syndrome., Ruoyun Xiong, Elizabeth Aiken, Ryan Caldwell, Suzanne D Vernon, Lina Kozhaya, Courtney Gunter, Lucinda Bateman, Derya Unutmaz, and Julia Oh
AI-driven multi-omics modeling of myalgic encephalomyelitis/chronic fatigue syndrome., Ruoyun Xiong, Elizabeth Aiken, Ryan Caldwell, Suzanne D Vernon, Lina Kozhaya, Courtney Gunter, Lucinda Bateman, Derya Unutmaz, and Julia Oh
Physiological role and mechanisms of action for a long noncoding haplotype region., Hong Xue, Manoj K Mishra, Yong Liu, Pengyuan Liu, Michael Grzybowski, Rajan Pandey, Kristie Usa, Mark A Vanden Avond, Niharika Bala, Abdel A Alli, Allen W Cowley, Qiongzi Qiu, Andrew S Greene, Sridhar Rao, Caitlin C O'Meara, Aron M Geurts, and Mingyu Liang
Intracranial germ cell tumors: advancement in genomic diagnostics and the need for novel therapeutics., Kee Kiat Yeo, Joanna J Gell, Girish Dhall, and Ching C Lau
Complete sequencing of ape genomes., DongAhn Yoo, Arang Rhie, Prajna Hebbar, Francesca Antonacci, Glennis A Logsdon, Steven J Solar, Dmitry Antipov, Brandon D Pickett, Yana Safonova, Francesco Montinaro, Yanting Luo, Joanna Malukiewicz, Jessica M Storer, Jiadong Lin, Abigail N Sequeira, Riley J Mangan, Glenn Hickey, Graciela Monfort Anez, Parithi Balachandran, Anton Bankevich, Christine R Beck, Arjun Biddanda, Matthew Borchers, Gerard G Bouffard, Emry Brannan, Shelise Y Brooks, Lucia Carbone, Laura Carrel, Agnes P Chan, Juyun Crawford, Mark Diekhans, Eric Engelbrecht, Cedric Feschotte, Giulio Formenti, Gage H Garcia, Luciana de Gennaro, David Gilbert, Richard E Green, Andrea Guarracino, Ishaan Gupta, Diana Haddad, Junmin Han, Robert S Harris, Gabrielle A Hartley, William T Harvey, Michael Hiller, Kendra Hoekzema, Marlys L Houck, Hyeonsoo Jeong, Kaivan Kamali, Manolis Kellis, Bryce Kille, Chul Lee, Youngho Lee, William Lees, Alexandra P Lewis, Qiuhui Li, Mark Loftus, Yong Hwee Eddie Loh, Hailey Loucks, Jian Ma, Yafei Mao, Juan F I Martinez, Patrick Masterson, Rajiv C McCoy, Barbara McGrath, Sean McKinney, Britta S Meyer, Karen H Miga, Saswat K Mohanty, Katherine M Munson, Karol Pal, Matt Pennell, Pavel A Pevzner, David Porubsky, Tamara Potapova, Francisca R Ringeling, Joana L Rocha, Oliver A Ryder, Samuel Sacco, Swati Saha, Takayo Sasaki, Michael C Schatz, Nicholas J Schork, Cole Shanks, Linnéa Smeds, Dongmin R Son, Cynthia Steiner, Alexander P Sweeten, Michael G Tassia, Françoise Thibaud-Nissen, Edmundo Torres-González, Mihir Trivedi, Wenjie Wei, Julie Wertz, Muyu Yang, Panpan Zhang, Shilong Zhang, Yang Zhang, Zhenmiao Zhang, Sarah A Zhao, Yixin Zhu, Erich D Jarvis, Jennifer L Gerton, Iker Rivas-González, Benedict Paten, Zachary A Szpiech, Christian D Huber, Tobias L Lenz, Miriam K Konkel, Soojin V Yi, Stefan Canzar, Corey T Watson, Peter H Sudmant, Erin Molloy, Erik Garrison, Craig B Lowe, Mario Ventura, Rachel J O'Neill, Sergey Koren, Kateryna D Makova, Adam M Phillippy, and Evan E Eichler
Elevated mitochondrial membrane potential is a therapeutic vulnerability in Dnmt3a-mutant clonal hematopoiesis., Kira Young, Mohsen Hosseini, Jayna J Mistry, Claudia Morganti, Taylor S Mills, Xiurong Cai, Brandon T James, Griffin J Nye, Natalie R Fournier, Veronique Voisin, Ali Chegini, Aaron D Schimmer, Gary D Bader, Grace Egan, Marc R Mansour, Grant A Challen, Eric M Pietras, Kelsey H Fisher-Wellman, Keisuke Ito, Steven M Chan, and Jennifer J. Trowbridge
The BIM deletion polymorphism potentiates the survival of leukemia stem and progenitor cells and impairs response to targeted therapies., Mengge Yu, Giselle Sek Suan Nah, Vaidehi Krishnan, Fatin Nasha Bte Sulaimi, King Pan Ng, Chuqi Wang, Shruti Bhatt, Charles Chuah, David E. Bergstrom, and S Tiong Ong
Artificial Intelligence and Machine Learning for Environmental Health Study., Miao Yu, Mingliang Fang, Zhenyu Tian, Bin Wang, and Douglas Walker
Ethical Frameworks for Data-Driven Environmental Health Studies in the AI Era, Miao Yu, Mingliang Fang, and Bin Wang
Ethical Frameworks for Data-Driven Environmental Health Studies in the AI Era., Miao Yu, Mingliang Fang, and Bin Wang
mzrtsim: Raw Data Simulation for Reproducible Gas/Liquid Chromatography-Mass Spectrometry-Based Nontargeted Metabolomics Data Analysis., Miao Yu and Vivek M. Philip
A Concordance Study among 26 NGS Laboratories Participating in the NCI Molecular Analysis for Therapy Choice Clinical Trial., Linda K Zane, Laura M Yee, Ting-Chia Chang, Jeffrey Sklar, Guangxiao Yang, Jia Di Wen, Peining Li, Robin Harrington, David J Sims, Kneshay Harper, Jeffrey M Trent, Janine R LoBello, Szabolcs Szelinger, Kasey Benson, Jia Zeng, Kelsey Poorman, Danbin Xu, Garrett M Frampton, Dean C Pavlick, Vincent A Miller, Bevan Tandon, Wojciech Swat, Lawrence Weiss, Vincent Anthony Funari, Jeffrey M Conroy, James L Prescott, Pranil K Chandra, Charles Ma, Kristen J Champion, Gregory X Baschkopf, Yuri A Fesko, Tracey Allen K Freitas, Scott A Tomlins, Daniel H Hovelson, Kevin White, Shelly Sorrells, Robert Tell, Nike Beaubier, David King, Lei Li, Kevin Kelly, Jasmina Uvalic, Bridgette Meyers, Ravindra Kolhe, Neal I Lindeman, Michele Baltay, Lynette M Sholl, Jean Lopategui, Eric Vail, Wenjuan Zhang, Milhan Telatar, Michelle Afkhami, Susan J Hsiao, Mahesh M Mansukhani, Emily Adams, LiQun Jiang, for the NCI-MATCH Designated Laboratories, Kenneth D Aldape, Mark Raffeld, Liqiang Xi, for NCI-COMPASS Team, Henning Stehr, Jeremy P Segal, Dara L Aisner, Kurtis D Davies, Noah A Brown, Robert J Livingston, Eric Q Konnick, Wei Song, James P Solomon, Zenta Walther, for NCI-MATCH Designated Laboratories, Lisa M McShane, Lyndsay N Harris, Alice P Chen, Gregory J Tsongalis, Stanley R Hamilton, Keith T Flaherty, Peter J O'Dwyer, Barbara A Conley, David R Patton, A John Iafrate, P Mickey Williams, James V Tricoli, and Chris Karlovich
TLR4 deficiency does not alter glaucomatous progression in a mouse model of chronic glaucoma., Chi Zhang, Marina Simón, Jeffrey M. Harder, Haeyn Lim, Christa Montgomery, Qing Wang, and Simon W M John
Artificial intelligence-based digital pathology using H&E-stained whole slide images in immuno-oncology: from immune biomarker detection to immunotherapy response prediction., Jessica Zhang, Horyun Choi, Yeseul Kim, Jonghanne Park, Sukjoo Cho, Eugene Kim, Allen Cho, Ju Young Lee, Jaeyoun Choi, Christmann Low, Chan Mi Jung, Emma J Yu, Jeffrey Chuang, Lee Cooper, and Young Kwang Chae
TRP Channels in Excitotoxicity., Pengyu Zong, Nicholas Legere, Jianlin Feng, and Lixia Yue
TRPM2 overactivation drives hyperlipidemia-induced dysfunction of myeloid cells and neurovascular units., Pengyu Zong, Cindy Li, Jianlin Feng, Zhichao Yue, Nicholas Legere, Albert S Yu, Fahad Shah, Adrianna Perez, Zhu Li, Evan Jellison, Yasuo Mori, Barbara Miller, Rajkumar Verma, Bruce Liang, and Lixia Yue
Submissions from 2024
The ClinGen Syndromic Disorders Gene Curation Expert Panel: Assessing the Clinical Validity of 111 Gene-Disease Relationships., Eleanor Broeren, Vanessa Gitau, Alicia Byrne, Pamela Ajuyah, Marie Balzotti, Jonathan Berg, Krista Bluske, B Monica Bowen, Matthew P Brown, Amanda Buchanan, Brendan Burns, Nicole J Burns, Anjana Chandrasekhar, Aditi Chawla, Jessica Chong, Maya Chopra, Amanda Clause, Marina DiStefano, Stephanie DiTroia, Marwa Elnagheeb, Amanda Girod, Himanshu Goel, Katie Golden-Grant, Thuong Ha, Ada Hamosh, Jennifer Huang, Madeline Hughes, Saumya Jamuar, Sylvia Kam, Akanchha Kesari, Ai Ling Koh, Rhonda Lassiter, Sarah Leigh, Gabrielle Lemire, Jiin Ying Lim, Alka Malhotra, Hannah McCurry, Becky Milewski, Shahida Moosa, Stephen A Murray, Emma Owens, Emma Palmer, Brooke Palus, Mayher Patel, Revathi Rajkumar, Julie Ratliff, F Lucy Raymond, Bruno Della Ripa Rodrigues Assis, Samin Sajan, Zinayida Schlachetzki, Sarah Schmidt, Zornitza Stark, Samuel Strom, Julie Taylor, Courtney Thaxton, Devon Thrush, Sabrina Toro, Kezang Tshering, Nicole Vasilevsky, Bess Wayburn, Ryan Webb, Anne O'Donnell-Luria, and Alison J Coffey
Folic Acid and Methyltetrahydrofolate Supplementation in the, Karen E Christensen, Marie-Lou Faquette, Daniel Leclerc, Vafa Keser, Yan Luan, Jeanna L Bennett-Firmin, Olga V Malysheva, Alaina M Reagan, Gareth R Howell, Marie A Caudill, Teodoro Bottiglieri, and Rima Rozen
Genomic medicine year in review: 2024., Teri A Manolio, Jahnavi Narula, Alauna Rupert, Carol J Bult, Rex L Chisholm, Geoffrey S Ginsburg, Eric D Green, Gillian Hooker, Gail P Jarvik, George A Mensah, Erin M Ramos, Dan M Roden, Robb Rowley, Casey Overby Taylor, and Marc S Williams
Human iPSC-derived microglia sense and dampen hyperexcitability of cortical neurons carrying the epilepsy-associated, Zhefu Que, Maria I Olivero-Acosta, Morgan Robinson, Ian Chen, Jingliang Zhang, Kyle Wettschurack, Jiaxiang Wu, Tiange Xiao, C Max Otterbacher, Vinayak Shankar, Hope Harlow, Seoyong Hong, Benjamin Zirkle, Muhan Wang, Ningren Cui, Purba Mandal, Xiaoling Chen, Brody Deming, Manasi Halurkar, Yuanrui Zhao, Jean-Christophe Rochet, Ranjie Xu, Amy L Brewster, Long-Jun Wu, Chongli Yuan, William C Skarnes, and Yang Yang