Submissions from 2012
HDL cholesterol and bone mineral density: is there a genetic link?, Cheryl L Ackert-Bicknell
Genetic variation in TRPS1 may regulate hip geometry as well as bone mineral density., Cheryl L Ackert-Bicknell, Serkalem Demissie, Shirng-Wern Tsaih, Wesley G Beamer, L Adrienne Cupples, Beverly J Paigen, Yi-Hsiang Hsu, Douglas P Kiel, and David Karasik
Loss of correlations among proteins in brains of the Ts65Dn mouse model of down syndrome., Md Mahiuddin Ahmed, Xiaolu Sturgeon, Misoo Ellison, M T. Davisson, and Katheleen J Gardiner
Pla2g12b and Hpn Are Genes Identified by Mouse ENU Mutagenesis That Affect HDL Cholesterol., Aleksandra Aljakna, Seungbum Choi, Holly Savage, Rachael Hageman Blair, Tongjun Gu, Karen L Svenson, Gary A Churchill, Matt Hibbs, and Ron Korstanje
A mouse model of clonal CD8+ T lymphocyte-mediated alopecia areata progressing to alopecia universalis., Rajshekhar Alli, Phuong Nguyen, Kelli Boyd, John P Sundberg, and Terrence L Geiger
Anti-carcinoembryonic Antigen Single-chain Variable Fragment Antibody Variants Bind Mouse and Human Neonatal Fc Receptor with Different Affinities That Reveal Distinct Cross-species Differences in Serum Half-life., Jan Terje Andersen, Stian Foss, Vania E Kenanova, Tove Olafsen, Ingvild S Leikfoss, Derry C Roopenian, Anna M Wu, and Inger Sandlie
Gene expression patterns in the hippocampus and amygdala of endogenous depression and chronic stress models., B M Andrus, K Blizinsky, P T Vedell, K Dennis, P K Shukla, D J Schaffer, J Radulovic, Gary A. Churchill, and E E Redei
Gene expression in mouse oocytes by RNA-Seq., Eric Antoniou and Robert Taft
Concept annotation in the CRAFT corpus., Michael Bada, Miriam Eckert, Donald Evans, Kristin Garcia, Krista Shipley, Dmitry Sitnikov, William A Baumgartner, K Bretonnel Cohen, Karin Verspoor, Judith A Blake, and Lawrence E Hunter
GeneWeaver: a web-based system for integrative functional genomics., Erich J Baker, Jeremy J Jay, Jason A Bubier, Michael A Langston, and Elissa J Chesler
The influence of genetic factors on the osteoinductive potential of calcium phosphate ceramics in mice., Ana M C Barradas, Huipin Yuan, Johan van der Stok, Bach Le Quang, Hugo Fernandes, Anindita Chaterjea, Marieke C H Hogenes, Kathy Shultz, Leah Rae Donahue, Clemens van Blitterswijk, and Jan de Boer
Diversity of spontaneous neoplasms in commonly used inbred strains of laboratory mice., Dale Begley, Beth A. Sundberg, Annerose Berndt, Janan Eppig, Paul N. Schofield, and John P. Sundberg
Disease model curation improvements at Mouse Genome Informatics., Susan M Bello, Joel E Richardson, Allan P Davis, Thomas C Wiegers, Carolyn J Mattingly, Mary E Dolan, Cynthia L Smith, Judith A Blake, and Janan T Eppig
Humanized mouse model used to monitor MUC gene expression in nasal polyps and to preclinically evaluate the efficacy of montelukast in reducing mucus production., Joel M Bernstein, Heather Lehman, Maciej Lis, Amy Sands, Gregory E Wilding, Leonard Shultz, Richard Bankert, and Libuse Bobek
The progression from obesity to type 2 diabetes in Alström syndrome., Vera Bettini, Pietro Maffei, Claudio Pagano, Sara Romano, Gabriella Milan, Francesca Favaretto, Jan D Marshall, Richard Paisey, Francesco Scolari, Nella A Greggio, Ilaria Tosetto, Jürgen K Naggert, Nicola Sicolo, and Roberto Vettor
What can causal networks tell us about metabolic pathways?, Rachael Hageman Blair, Daniel J Kliebenstein, and Gary A Churchill
Critical function for the Ras-GTPase activating protein RASA3 in vertebrate erythropoiesis and megakaryopoiesis., Lionel Blanc, Steven L Ciciotte, Babette Gwynn, Gordon J Hildick-Smith, Eric L Pierce, Kathleen A Soltis, Jeffrey D Cooney, Barry H Paw, and Luanne L Peters
A MusD retrotransposon insertion in the mouse Slc6a5 gene causes alterations in neuromuscular junction maturation and behavioral phenotypes., Laurent P Bogdanik, Harold D Chapman, Kathy E Miers, David V Serreze, and Robert W Burgess
The mammalian gene function resource: the international knockout mouse consortium., Allan Bradley, Konstantinos Anastassiadis, Abdelkader Ayadi, James F Battey, Cindy Bell, Marie-Christine Birling, Joanna Bottomley, Steve D Brown, Antje Bürger, Carol J Bult, Wendy Bushell, Francis S Collins, Christian Desaintes, Brendan Doe, Aris Economides, Janan T Eppig, Richard H Finnell, Colin Fletcher, Martin Fray, David Frendewey, Roland H Friedel, Frank G Grosveld, Jens Hansen, Yann Hérault, Geoffrey Hicks, Andreas Hörlein, Richard Houghton, Martin Hrabé de Angelis, Danny Huylebroeck, Vivek Iyer, Pieter J de Jong, James A Kadin, Cornelia Kaloff, Karen Kennedy, Manousos Koutsourakis, K C Kent Lloyd, Susan Marschall, Jeremy Mason, Colin McKerlie, Michael P McLeod, Harald von Melchner, Mark Moore, Alejandro O Mujica, Andras Nagy, Mikhail Nefedov, Lauryl M Nutter, Guillaume Pavlovic, Jane L Peterson, Jonathan Pollock, Ramiro Ramirez-Solis, Derrick E Rancourt, Marcello Raspa, Jacques E Remacle, Martin Ringwald, Barry Rosen, Nadia Rosenthal, Janet Rossant, Patricia Ruiz Noppinger, Ed Ryder, Joel Zupicich Schick, Frank Schnütgen, Paul Schofield, Claudia Seisenberger, Mohammed Selloum, Elizabeth M Simpson, William C Skarnes, Damian Smedley, William L Stanford, A Francis Stewart, Kevin Stone, Kate Swan, Hamsa Tadepally, Lydia Teboul, Glauco P Tocchini-Valentini, David Valenzuela, Anthony P West, Ken-Ichi Yamamura, Yuko Yoshinaga, and Wolfgang Wurst
Bone morphogenetic protein receptor type Ia localization causes increased BMP2 signaling in mice exhibiting increased peak bone mass phenotype., Beth Bragdon, Jeremy Bonor, Kathryn L Shultz, Wesley G Beamer, Clifford J Rosen, and Anja Nohe
Altered plasma membrane dynamics of bone morphogenetic protein receptor type Ia in a low bone mass mouse model., Beth Bragdon, Alex D'Angelo, Lauren Gurski, Jeremy Bonor, Kathryn L Schultz, Wesley G Beamer, Clifford J. Rosen, and Anja Nohe
Advancing animal models of human type 1 diabetes by engraftment of functional human tissues in immunodeficient mice., Michael A Brehm, Alvin C Powers, Leonard D Shultz, and Dale L Greiner
Engraftment of human HSCs in nonirradiated newborn NOD-scid IL2rγ null mice is enhanced by transgenic expression of membrane-bound human SCF., Michael A Brehm, Waldemar J Racki, Jean Leif, Lisa Burzenski, Vishnu Hosur, Amber Wetmore, Bruce Gott, Mary Herlihy, Ronald Ignotz, Raymond Dunn, Leonard D Shultz, and Dale L Greiner
Human allograft rejection in humanized mice: a historical perspective., Michael A Brehm and Leonard D Shultz
In vivo evidence for the crucial role of SF1 in steroid-producing cells of the testis, ovary and adrenal gland., F William Buaas, Jennifer R Gardiner, Sally Clayton, Pierre Val, and Amanda Swain
Accelerating discovery for complex neurological and behavioral disorders through systems genetics and integrative genomics in the laboratory mouse., Jason A Bubier and Elissa J Chesler
Mouse genomics programs and resources : The mouse: pushing the boundaries., Maja Bucan, Janan T Eppig, and Steve Brown
Bioinformatics resources for behavior studies in the laboratory mouse., Carol J. Bult
Contact is repulsive, but please note the "enclosed"., Robert W Burgess, Andrew M Garrett, and Abigail L D Tadenev
Mouse estrous cycle identification tool and images., Shannon L Byers, Michael V Wiles, Sadie L Dunn, and Robert A Taft
Host genetic and environmental effects on mouse intestinal microbiota., James H Campbell, Carmen M Foster, Tatiana Vishnivetskaya, Alisha G Campbell, Zamin K Yang, Ann Wymore, Anthony V Palumbo, Elissa J Chesler, and Mircea Podar
Motor terminal degeneration unaffected by activity changes in SOD1(G93A) mice; a possible role for glycolysis., Dario I Carrasco, Edyta K Bichler, Mark M Rich, Xueyong Wang, Kevin L Seburn, and Martin J Pinter
Predicting the effects of copy-number variation in double and triple mutant combinations., Gregory W. Carter, Michelle Hays, Song Li, and Timothy Galitski
Use of pleiotropy to model genetic interactions in a population., Gregory W Carter, Michelle Hays, Amir Sherman, and Timothy Galitski
MouseFinder: Candidate disease genes from mouse phenotype data., Chao-Kung Chen, Christopher J Mungall, Georgios V Gkoutos, Sandra C Doelken, Sebastian Köhler, Barbara J Ruef, Cynthia Smith, Monte Westerfield, Peter N Robinson, Suzanna E Lewis, Paul N Schofield, and Damian Smedley
Genetic control of murine invariant natural killer T-cell development dynamically differs dependent on the examined tissue type., Y-G Chen, S-W Tsaih, and D V Serreze
The field of bioinformatics. Preface., Elissa J Chesler and Melissa A Haendel
Opportunities for bioinformatics in the classification of behavior and psychiatric disorders., Elissa J. Chesler and Ryan W Logan
Quantitative trait loci for sensitivity to ethanol intoxication in a C57BL/6J×129S1/SvImJ inbred mouse cross., Elissa J Chesler, Aaron Plitt, Daniel Fisher, Benita Hurd, Lauren Lederle, Jason A Bubier, Carly Kiselycznyk, and Andrew Holmes
A Direct HDAC4-MAP Kinase Crosstalk Activates Muscle Atrophy Program., Moon-Chang Choi, Todd J Cohen, Tomasa Barrientos, Bin Wang, Ming Li, Bryan J Simmons, Jeong Soo Yang, Gregory A Cox, Yingming Zhao, and Tso-Pang Yao
Monoclonal antibodies directed against human FcRn and their applications., Gregory J Christianson, Victor Z Sun, Shreeram Akilesh, Emanuele Pesavento, Gabriele Proetzel, and Derry C Roopenian
The diversity outbred mouse population., Gary A Churchill, Daniel M Gatti, Steven C Munger, and Karen L Svenson
The Alström Syndrome Protein, ALMS1, Interacts with α-Actinin and Components of the Endosome Recycling Pathway., Gayle B Collin, Jan D Marshall, Benjamin L King, Gabriella Milan, Pietro Maffei, Daniel J Jagger, and Jürgen K Naggert
Meckelin is necessary for photoreceptor intraciliary transport and outer segment morphogenesis., Gayle B Collin, Jungyeon Won, Wanda L Hicks, Susan A Cook, Patsy M Nishina, and Jürgen K Naggert
The genome architecture of the Collaborative Cross mouse genetic reference population., Collaborative Cross Consortium
The Gene Ontology: enhancements for 2011., Gene Ontology Consortium
Sex reversal in C57BL/6J XY mice caused by increased expression of ovarian genes and insufficient activation of the testis determining pathway., Stephanie M Correa, Linda L Washburn, Ravi S Kahlon, Michelle C Musson, Gerrit J Bouma, Eva M Eicher, and Kenneth H Albrecht
Genome-wide association mapping of loci for antipsychotic-induced extrapyramidal symptoms in mice., James J Crowley, Yunjung Kim, Jin Peng Szatkiewicz, Amanda L Pratt, Corey R Quackenbush, Daniel E Adkins, Edwin van den Oord, Molly A Bogue, Hyuna Yang, Wei Wang, David W Threadgill, Fernando Pardo-Manuel de Villena, Howard L McLeod, and Patrick F Sullivan
Heme oxygenase-1 regulates the immune response to influenza virus infection and vaccination in aged mice., Nathan W Cummins, Eric A Weaver, Shannon M May, Anthony J Croatt, Oded Foreman, Richard B Kennedy, Gregory A Poland, Michael A Barry, Karl A Nath, and Andrew D Badley
A unified anatomy ontology of the vertebrate skeletal system., Wasila M Dahdul, James P Balhoff, David C Blackburn, Alexander D Diehl, Melissa A Haendel, Brian K Hall, Hilmar Lapp, John G Lundberg, Christopher J Mungall, Martin Ringwald, Erik Segerdell, Ceri E Van Slyke, Matthew K Vickaryous, Monte Westerfield, and Paula M Mabee
Proteotoxic stress of cancer: implication of the heat-shock response in oncogenesis., Chengkai Dai, Siyuan Dai, and Junyue Cao
Loss of tumor suppressor NF1 activates HSF1 to promote carcinogenesis., Chengkai Dai, Sandro Santagata, Zijian Tang, Jiayuan Shi, Junxia Cao, Hyoungtae Kwon, Roderick T Bronson, Luke Whitesell, and Susan Lindquist
Discovery genetics: the history and future of spontaneous mutation research., Muriel T. Davisson, David E. Bergstrom, Laura G. Reinholdt, and Leah Rae Donahue
Toward community standards in the quest for orthologs., Christophe Dessimoz, Toni Gabaldón, David S Roos, Erik L L Sonnhammer, and Javier Herrero
Discovery of novel variants in genotyping arrays improves genotype retention and reduces ascertainment bias., John P Didion, Hyuna Yang, Keith Sheppard, Chen-Ping Fu, Leonard McMillan, Fernando Pardo-Manuel de Villena, and Gary A Churchill
Inflammation and disruption of the mucosal architecture in claudin-7-deficient mice., Lei Ding, Zhe Lu, Oded Foreman, Rodney Tatum, Qun Lu, Randall Renegar, Jian Cao, and Yan-Hua Chen
CodingMotif: exact determination of overrepresented nucleotide motifs in coding sequences., Yang Ding, William A Lorenz, and Jeffrey Chuang
Centralized mouse repositories., Leah Rae Donahue, Martin Hrabe de Angelis, Michael Hagn, Craig Franklin, K C Kent Lloyd, Terry Magnuson, Colin McKerlie, Naomi Nakagata, Yuichi Obata, Stuart Read, Wolfgang Wurst, Andreas Hörlein, and Muriel T Davisson
Manual Gene Ontology annotation workflow at the Mouse Genome Informatics Database., Harold J Drabkin and Judith A Blake
Antigen presentation for the generation of binding molecules., Hilmar Ebersbach, Gabriele Proetzel, and Chonghui Zhang
The Mouse Genome Database (MGD): comprehensive resource for genetics and genomics of the laboratory mouse., Janan T Eppig, Judith A Blake, Carol J Bult, James A Kadin, and Joel E Richardson
Origins of granulosa cells clarified and complexified by waves., John J Eppig and Mary Ann Handel
JNK2 and JNK3 are major regulators of axonal injury-induced retinal ganglion cell death., Kimberly A Fernandes, Jeffrey M Harder, Laura B Fornarola, Robert S Freeman, Abbot F Clark, Iok-Hou Pang, Simon W M John, and Richard T Libby
How the evolutionary theory of aging can guide us in the search for aging genes., Kevin Flurkey and Rong Yuan
Life sciences domain analysis model., Robert R Freimuth, Elaine T Freund, Lisa Schick, Mukesh K Sharma, Grace A Stafford, Baris E Suzek, Joyce Hernandez, Jason Hipp, Jenny M Kelley, Konrad Rokicki, Sue Pan, Andrew Buckler, Todd H Stokes, Anna Fernandez, Ian Fore, Kenneth H Buetow, and Juli D Klemm
A model for Escherichia coli chromosome packaging supports transcription factor-induced DNA domain formation., Miriam Fritsche, Songling Li, Dieter W Heermann, and Paul A Wiggins
The impact of entropy on the spatial organization of synaptonemal complexes within the cell nucleus., Miriam Fritsche, Laura G Reinholdt, Mark Lessard, Mary Ann Handel, Jörg Bewersdorf, and Dieter W Heermann
Cell autonomy of DSCAM function in retinal development., Peter G Fuerst, Freyja Bruce, Ryan P Rounds, Lynda Erskine, and Robert W Burgess
Algorithm for codevelopment of new drug-predictive biomarker combinations: accounting for inter- and intrapatient tumor heterogeneity., David R Gandara, Tianhong Li, Primo N Lara, Philip C Mack, Karen Kelly, Suzanne Miyamoto, Neal C. Goodwin, Laurel Beckett, and Mary W Redman
DSCAMs: restoring balance to developmental forces., Andrew M Garrett, Abigail L D Tadenev, and Robert W Burgess
Recent advances in biocuration: Meeting Report from the fifth International Biocuration Conference., Pascale Gaudet, Cecilia Arighi, Frederic Bastian, Alex Bateman, Judith A Blake, Michael J Cherry, Peter D'Eustachio, Robert Finn, Michelle Giglio, Lynette Hirschman, Renate Kania, William Klimke, Maria Jesus Martin, Ilene Karsch-Mizrachi, Monica Munoz-Torres, Darren Natale, Claire O'Donovan, Francis Ouellette, Kim D Pruitt, Marc Robinson-Rechavi, Susanna-Assunta Sansone, Paul Schofield, Granger Sutton, Kimberly Van Auken, Sona Vasudevan, Cathy Wu, Jasmine Young, and Raja Mazumder
Deregulated sex chromosome gene expression with male germ cell-specific loss of dicer1., Anne R Greenlee, Meng-Shin Shiao, Elizabeth Snyder, F William Buaas, Tongjun Gu, Timothy M Stearns, Manju Sharma, Elizabeth P Murchison, Gabriella C Puente, and Robert E Braun
Tissue-specific functional networks for prioritizing phenotype and disease genes., Yuanfang Guan, Dmitriy Gorenshteyn, Margit Burmeister, Aaron K Wong, John C. Schimenti, Mary Ann Handel, Carol J Bult, Matthew A Hibbs, and Olga G Troyanskaya
Canonical A-to-I and C-to-U RNA Editing Is Enriched at 3'UTRs and microRNA Target Sites in Multiple Mouse Tissues., Tongjun Gu, Frank W Buaas, Allen K Simons, Cheryl L Ackert-Bicknell, Robert E Braun, and Matthew A Hibbs
Transcription factor Ebf1 regulates differentiation stage-specific signaling, proliferation, and survival of B cells., Ildiko Györy, Sören Boller, Robert Nechanitzky, Elizabeth Mandel, Sebastian Pott, Edison Liu, and Rudolf Grosschedl
Polymer-based miniature flexible capacitive pressure sensor for intraocular pressure (IOP) monitoring inside a mouse eye., Dohyuk Ha, Wilhelmine N de Vries, Simon W M John, Pedro P Irazoqui, and William J Chappell
A compact-size packaged third-order harmonic tag for intraocular pressure (IOP) monitoring inside a mouse eye., Dohyuk Ha, Tse-Yu Lin, Wilhelmine N. de Vries, Byungguk Kim, Arthur L. Chlebowski, Simon W M John, Pedro P. Irazoqui, and William J. Chappell
Lost and found in behavioral informatics., Melissa A Haendel and Elissa J Chesler
Activation-Induced Cytidine Deaminase-Initiated Off-Target DNA Breaks Are Detected and Resolved during S Phase., Muneer G Hasham, Kathy J Snow, Nina M Donghia, Jane A Branca, Mark D Lessard, Janet Stavnezer, Lindsay S. Shopland, and Kevin D Mills
Genome-wide microarray comparison reveals downstream genes of Pax6 in the developing mouse cerebellum., Thomas J Ha, Douglas J Swanson, Roumyana Kirova, Joanna Yeung, Kunho Choi, Yiai Tong, Elissa J Chesler, and Daniel Goldowitz
The mouse-human anatomy ontology mapping project., Terry F Hayamizu, Sherri de Coronado, Gilberto Fragoso, Nicholas Sioutos, James A Kadin, and Martin Ringwald
Mitotic chromosome structure., Dieter W Heermann
A model for the 3D chromatin architecture of pro and eukaryotes., Dieter W Heermann, Hansjoerg Jerabek, Lei Liu, and Yixue Li
Supporting conditional mouse mutagenesis with a comprehensive cre characterization resource., Caleb S Heffner, C Herbert Pratt, Randal P Babiuk, Yashoda Sharma, Stephen F Rockwood, Leah R Donahue, Janan T Eppig, and Stephen A Murray
Dystrophin and dysferlin double mutant mice: a novel model for rhabdomyosarcoma., Vishnu Hosur, Anoop Kavirayani, Jennifer Riefler, Lisa M B Carney, Bonnie Lyons, Bruce Gott, Gregory A Cox, and Leonard D Shultz
Radiation treatment inhibits monocyte entry into the optic nerve head and prevents neuronal damage in a mouse model of glaucoma., Gareth R Howell, Ileana Soto, Xianjun Zhu, Margaret Ryan, Danilo G Macalinao, Gregory L Sousa, Lura B Caddle, Katharine H MacNicoll, Jessica M Barbay, Vittorio Porciatti, Michael G Anderson, Richard S Smith, Abbot F Clark, Richard T Libby, and Simon W M John
Contribution of a single host genetic locus to mouse adenovirus type 1 infection and encephalitis., Tien-Huei Hsu, Irene W Althaus, Oded Foreman, and Katherine R Spindler
Structural mutations in cancer: mechanistic and functional insights., Koichiro Inaki and Edison T Liu
Antibody repertoires in humanized NOD-scid-IL2Rγ(null) mice and human B cells reveals human-like diversification and tolerance checkpoints in the mouse., Gregory C Ippolito, Kam Hon Hoi, Sai T Reddy, Sean M Carroll, Xin Ge, Tobias Rogosch, Michael Zemlin, Leonard D Shultz, Andrew D Ellington, Carla L Vandenberg, and George Georgiou
Enhanced humoral and HLA-A2-restricted dengue virus-specific T-cell responses in humanized BLT NSG mice., Smita Jaiswal, Pamela Pazoles, Marcia Woda, Leonard D Shultz, Dale L Greiner, Michael A Brehm, and Anuja Mathew
Cross species integration of functional genomics experiments., Jeremy J Jay
A systematic comparison of genome-scale clustering algorithms., Jeremy J Jay, John D Eblen, Yun Zhang, Mikael Benson, Andy D Perkins, Arnold M Saxton, Brynn H Voy, Elissa J Chesler, and Michael A Langston
Mutation of a U2 snRNA gene causes global disruption of alternative splicing and neurodegeneration., Yichang Jia, John C Mu, and Susan L. Ackerman
Molecular diagnosis of a laboratory mouse papillomavirus (MusPV)., Joongho Joh, A Bennett Jenson, Mary Proctor, Arvind Ingle, Kathleen A Silva, Christopher S Potter, John P Sundberg, and Shin-Je Ghim
Association of a citrate synthase missense mutation with age-related hearing loss in A/J mice., Kenneth R Johnson, Leona H Gagnon, Chantal Longo-Guess, and Kelly L Kane
Mutations of the mouse ELMO domain containing 1 gene (Elmod1) link small GTPase signaling to actin cytoskeleton dynamics in hair cell stereocilia., Kenneth R Johnson, Chantal M Longo-Guess, and Leona H Gagnon
Polo-like kinase is required for synaptonemal complex disassembly and phosphorylation in mouse spermatocytes., Philip W Jordan, Jesse Karppinen, and Mary Ann Handel
Genetic background effects on age-related hearing loss associated with Cdh23 variants in mice., Kelly L Kane, Chantal M Longo-Guess, Leona H Gagnon, Dalian Ding, Richard J Salvi, and Kenneth R Johnson
Primary neoplasms of bones in mice: retrospective study and review of literature., A M Kavirayani, J P Sundberg, and O Foreman
Neuronal clustering and fasciculation phenotype in Dscam- and Bax-deficient mouse retinas., Patrick W Keeley, Buranee J Sliff, Sammy C S Lee, Peter G Fuerst, Robert W Burgess, Stephen J Eglen, and Benjamin E Reese