The Summer Student Program began in 1924 when University of Maine President C.C. Little (our founder) brought six undergraduates to Mount Desert Island for a summer of biological field studies. The Summer Student Program officially became a part of the Jackson Memorial Laboratory's operation in 1931.

Students participate in an ongoing research program with the support of an experienced scientific mentor. They develop an independent project, implement their plan, analyze the data, and report the results. At the end of the summer, they present their findings to researchers, other students, and parents.

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Submissions from 1980

The effect of dimethylsulfoxide (DMSO) upon spontaneous amyloidosis in LLC mice., Leslie Ellen Eisenbud

The effect of autoclaving on induction of hepatic microsomal enzymes by four different bedding materials., Lisa C. Freeman

The stability of 3-hydroxy-3 methylglutary coenzyme A (HMG-CoA) reductase [mevalonate: NADP oxidoreductase (Co A aculating) EC 1.1.1.34] and other proteins in enucleated chinese hamster ovary (CHO) tissue culture cells., Steven M. Gordon

Trisomy 16 in the mouse., John Hastings

Immunohistochemical and biochemical studies of SN-glycerol-3-phosphate dehydrogenase development in the central and peripheral nervous systems of normal and mutant mice., Mark Stephen Kindy

B and T lymphocyte frequencies in autoimmune C3H/HeJ-gld/gld mice., Christine M. Kline

Serum and tumor lysosome levels in relation to macrophage activity., Hara Levy

The effects of verying retinol and cholesterol dietary levels on glycoprotein synthesis in mice., Marguerite McNeely

The effect of the "hairless" mutation on the T lymphocyte cell subpopulations in SJL/J mice., Rose Louise Morello

Putative glucagon precursors in long-term islet cell cultures., Michael Morley

Developing a better technique for the cryopreservation of rabbit embryos., Stuart S. Remer

The effects of oxygenated sterosis upon moloney sarcoma virus induced tumor growth., Scott Salowe

Analysis of the antigenic sites on chicken red blood cells recognized by C57L/J mouse serum., Lenore Soodak

The effects of pituitary extraction on the growth of mouse prostatic epithelial cells in defined culture media., Joseph P. Tassoni

Changes with age in the ability of the kidney to adjust to sodium ion deprivation., James Van Horn

The effect of the Mlv-1 gene on modification of susceptibility to murine leukemia viruses., Dorothy F. Walker

The effect of PIV caging systems on the physiology of four strains of mice., Lisa Denise Wojan

Changes with age in iron-59 uptake of circulating red blood cells., Joseph L. Zawicki

The effect of food restriction, autophagy and prophagy on age-related changes in dietary efficiency., Joseph L. Zawicki

Submissions from 1979

The effect of adult thymectomy on tumor growth., Deborah L. Allen

Lymphocytic proliferation in bone marrow of HLC and LLC mice., Doris S. Atkinson

Dexamethasone induced immunosuppression and disease in mice., Ginette Beaudoin

Comparison of tumor growth in 3 day and 6 day thymectomized mice., Susan Bothwell

Strain and hormonal effects on the conditioned taste aversion in mice., Timothy P. Corfman

The roles of dibutyryl cyclic adenosine monophosphate and follicle stimulating hormone in the control of maturation in oocyte-cumulus complexes isolated from mouse ovaries., Theodore Y. Fong

Serum lysosome levels in tumor-bearing mice., Diane A. Gargano

The effects of a glutamine analog on growth of a glutamine- requiring mouse tumor cell line in culture., Christine H. James

Progrssive loss of immune response in (NZB x BXSB) F 1 hybrid males showing accelerated spontaneous autoimmune disease., Baldev Krishan

Electrophoretic analysis of the spectrin component in the erythrocyte membrane of the jaundiced mouse., Patricia M. Matos

Ontogeny of sensorimotor asymmetries in mice selected for high and low lateralization., Pamela A. Mikuni

Studies of postnatal mouse cerebellar cells in vitro., Cynthia K. Miller

The in vivo effects of cytochalasin B on migrating primordial germ cells in the mouse embryo., Elissa A. Notarianni

Changes in renal function with age: antidiuretic hormone response., Eileen M. Poulin

Genetic control of the accessibility of H-2 antigens on the surface of erythrocytes., Allan J. Redstone

Studies of streptozotocin-induced diabetes and insulitis in mice., Eric Jay Small

The development of cleft lip on homozygote twirler and dancer mutants., Heidi K. Spindell

Inhibitive effects of compactin on assays of HMG-CoA reductase activity., Henry M. Sucov

Collagen solubility by hydroxyproline assay in mice skin of varying ages., Alexis E. Te

A biochemical investigation of cadmium-induced testicular necrosis in the mouse., Thomas F. Vogt

Immunogenicity of MCA-induced lung adenomas., Samdra E. Wakefield

Immunomodulation of antibody responses., Ellen Weinstein

Handling and caging stress resulting in cardiac calcification in DBA/2J mice., Lee J. Whiting

Submissions from 1978

The role of cholesterol in endocytosis of mammalian plasma membranes., Hillel R. Alpert

Assessment of a breeding program selective for differing degrees of lateralization., Daniel M. Becker

The estrous cycle and mating behavior of the mouse and stimuli that affect them., Brian L. Bournival

Determination of immunocompetance in the autoimmune (NZB X BXSB)F1 hybrid male mouse., Michael J. Brase

Lysis of type-C retroviruses by rabbit sera., Lorna L. Burnside

Aging and changes in systolic blood pressure levels in a C57B1/6J strain of mice., Michael S. Cafferty

The effect of dilantin and stress on serum calcium levels in mouse strain DBA/2J and hybrid B6D2F1., Karen P. Chen

Attempts to establish differences among normal homozygotes and mice heterozygous for both obese (ob) and diabetes (db)., Davis Mark J

The role of the vomeronasal pathway in mediating the pheromone induced effect of early sexual maturation in female mice., Elizabeth A. Debski

Comparative cell proliferation of high leukocyte count versus low leukocyte count inbred lines., Mary E. Delany

A study of the relationship between H-2 haplotype and immune response in three strains of mice with related leukemia incidence., Adria Anne Elskus

Effects of immunization on survival rate of transferred embryos., Monique Gaudin

Glial cell markers in reaggregating cell cultures of mouse cerebellum., Marian Greenburg

Plasma cholesterol studies in laboratory mice., Debbie Heldman

Thyroid function in petite mice., Stella S. Kim

Isolation of natural agglutinins of chicken red blood cells from mouse serum., Cheryl C. Kuerer

Comparison of immunogenicities of 3-methylcholanthrene-induced tumors of female origin in male and female C57B1/6J mice., Sherry Licht

The fertilizing ability of various concentrations of uterine and epididymal sperm., Kristin Lynes

Modifications on the Bernstein-Scheinberg erythropoietin assay., Jane Miller

An investigation of ethanol respose, central nervous system sensitivity and tetrahydroisoquinolines., Lawrence J. Moray

Relationship between dietary calcium, serum calcium levels, and heart calcific deposits in DBA/sJ and C57B1/6J x DBA/2J mice., Lucille J. Poulin

The effects of immunization of the host mother on the survival of transferred embryos., William M. Pulliam

The hypothalamus and humoral control of insulin secretion by the endocrine pancreas in normal and diabetic mice., Steven W. Rice

Experiments in macrophage reconstitution., Paul Rose

The effects of benserazide in combination with carboxy- salsolinol on central nervous system sensitivity to alcohol., Hillary Segl

Delta cell population changes in murine diabetes., John Steinert

Macrophage activity and leukemogenesis in HRS/J mice., Robert G. Terrill

Phospholipid synthesis in wild type(CHO) and 25-hydroxycholesterol resistant mutant (R2) chinese hamster ovary cells., Rebecca T. Upham

Submissions from 1977

The use of sister chromatid exchange analysis in vivo to find mouse models of human chromosomal breakage syndromes., Michael Absatz

Cell adhesion to solid surfaces: the effect of membrane deformation., Bridgette A. Barry

The effects of certain parameters on agarose suppression of the non-specific cytotoxicity of rabbit serum complement., David A. Brancaccio

Preliminary protein analysis of the murine zona pellucida., Molly Burchell

Taste preferences in inbred mice: validation and use of a short-term fluid intake measure., April Chang

Isoelectric focusing: a search for biochemical polymorphisms in adult and embryonic mouse blood., Gary T. Copland

The effect of 7-ketocholesterol on tumors in vivo., Audrey-Renate Delphendahl

Analysis of three induced recessive lethal mutations in the mouse., Leslie A. Denson

Muscular dystrophy as a confirmation of the correlation between daily urinary creatinine excretion and muscle mass., Steve Dubin

The effects of age on alcohol and sweet preference in DBA/2J and C57BL/6J mice., Marianne T. Duddy

Effect of age on alcohol and sweet preference behavior in mice., Daniel J. Feller

Genetic control of tamase activity in the submaxillary gland of the mouse., Craig S. Gawlas

A comparison of the effects of audiogenic seizures and ECS induced seizures upon learning., Jessica W. Jerrard

Methods for determining body composition in the mouse: the effect of aging on body composition in the mouse., Thomas R. Klumpp

Inhibition of meiotic maturation of mouse oocytes., Sumi Koide

Expression of isozymes of L-glycerol 3-phosphate dehydrogenase in cultures of neuroblastoma., Judith R. Krieger

The development of the immune response as shown by the effect of immunized spleen cells on tumor growth., Lisa M. Letourneau

Relationship between sterol synthesis and stage of cell growth in murine embryonic cells in tissue culture., Anna V. Lewis

The effect of stress and caging on incidence and severity of cardiac calcification in DBA/2J mice., Deborah A. Lizak

Determination of new histocompatibility loci in the mouse genome by allozyme markers., Diane C. Louie

Graft rejection in immunomodulated mice., Henry C. Maguire

Effects of the inhibition of HMG-CoA reductase on glycoprotein synthesis., Barbara Marroccoli

The immune system of the obese mouse., Mary Ellen McCarthy

Postnatal development of cytochrome C oxidase activity in T/t6 mutant mice., David C. Moverman

Terminal deoxyribonucleotidyl transferase activity in thymocytes of inbred strains of mice., Christopher M. O'Connor

The varying effects of different buffered solutions on intraocular pressure., Luke F.X Pickett

The influence of humoral and genetic factors in regulating leukocyte concentration and the role of lymphocyte subpopulations in the elaboration of the immune response., Richard L. Reed

Hormonal requirements for growth of a mammary tumor in chemically defined media., Linda K. Russell

The effect of age on alcohol and sweet preference behavior in mice., Carolyn Sanders

The development of a new erythropoietic assay in vivo., David Scheinberg