Students participate in an ongoing research program with the support of an experienced scientific mentor. They develop an independent project, implement their plan, analyze the data, and report the results. At the end of the summer, they present their findings to researchers, other students, and parents.
Submissions from 1994
HDL levels and atherogenesis: a potential role for high density lipoprotein as an antioxident., Kelsey J. Webb
Submissions from 1993
A Comparison of the fertilizing capacity of cryopreserved and fresh spermatozoa collected from different areas of the male reproductive tract of mice., Sonya E. Barrineau
The Adipocyte P2/Uncoupling protein transgene: determining the effects on energy inefficiency., Christopher Marshall Bouton
Targeting of the BxH-2 retrovirus in myeloid leukemogenesis., Annabel Bradford
Effects of different mouse genotypes on sperm cryopreservation: a comparison of motility and abnormal forms in fresh and cryopreserved spermatozoa., Katherine Cardenas
Sequencing of the third endogenous ecotropic proviral insertion site in BxH-2 mice., Deborah Chen
Mechanisms of gallium nitrate modulation of diabetes in NOD mice., Emmie Chen
Linkage of hyperalphalipoproteinemia to the Apo A-1 locus and directing expression of apolipoprotein A 1 to macrophages., Connie Cheung
Patterns of protein tyrosine phosphorylation in motheaten and viable motheaten mice., Trac M. Duong
Proteins associated with alternately spliced ankyrin transcripts., Holly Ann Field
An Endocrinological characterization of Fat and Tubby: possible animal models for human noninsulin-dependant diabetes mellitus., Jason E. Frankel
Studies of two neurological mutations: Moonwalker on chromosome 7, and Stargazer on chromosome 15., Jennifer Gervais
Chromosome mapping by fluorescent in situ hybridization., Charles Harris
Characterization of B-lymphoid tyrosine kinase blk as a candidate gene for identifying the disorganization mutation., Florence Jean-Louis
Genetic predisposition to hypertension and gallstones in the inbred strains of mice., Bhupinder Khanuja
Genetic and dietary factors affecting gallstone formation., Bhupinder S. Khanuja
An analysis of the effects of chemotherapy and a hemoregulatory peptide on primitive hematopoietic stem cells., Carmen Mays
A High resolution genetic map and candidates for a minor histocompatibility gene., Huy Q. Nguyen
High-density lipoprotein levels and obesity in mice: understanding the paradox., Cynthia J. Osterling
Preparation of a targeting construct for the Zfa gene., Haley A. Perlick
Purification of the mouse Y chromosome by reversible mobilization and magnetic in situ hybridization labeling., Sudha Reddy
The Genetic mapping of single-gene phenotypes by linkage analysis with PCR-amplified microsatillites from pooled DNA., Phoebe Scott-Wyard
Purification of mouse chromosome 14 by reversible immobilization and magnetic labeling., Brad Stohr
Timing of fetal loss to murine MPS VII., Colleen Storzek
Obtaining four evenly spaced clones on chrmomsome 17 as the first step to deletion mapping of the t-complex., Marie S. Thearle
Development of spina Bifida in undulated/patch double mutants., Bianca Thomas
High density lipoprotein cholesterol: a study of its effects on aging and lipid peroxidation., Kelsey Jeannine Webb
Submissions from 1992
The chromosomal location of a gene that increases susceptibility to testicular teratomas., Carrie E. Berman
Enrichment of primitive hemopoietic stem cells: preparation of monoclonal antibodies and new approaches., William G. Blum
Regulation of IL-6 gene expression in tumor cells: to identify the serum factor(s) required for IL-1 to activate the cells., Brett Cassidy
A Mouse model used to understand the role of minor histocompatibility antigens in tumor immunity., Stormy Chamberlain
Ovarian granulosa cell tumorigenesis: phase II enzymes and immunohistochemical markers., Siew-Sim Cheah
Development of polycystic kidney disease in mutant mice., Jacob N. Claflin
Analysis of mononuclear cell populations in a new mouse model alopecia areata., Wade R. Cordy
Cloning and indentification of a "novel" oncogene., Peter B. Craig
Cytokine gene expression in cancer and the effects of lipopolysaccharide., Garret Djeu
Influences of Ph on W., Amy E. Dunlop
The Effects of gender and dehydroepiandrosterone-sulfate on the aging immune system., Avery W. Gardiner
Developmental and hormone regulation of B-glucuronidase gene expression in transgenic mice., Randy Goethke
Erythropoiesis and erythrocyte survival in alpha-thalassemic mice., Jennifer M. Greer
The Effects of sodium orthovanadate administration on plasma lipid levels in C57BL/Ks-db/db mice., Julie Harris
Genetic predisposition to hypertension and atherosclerosis: exploration with SWR/J and SJL/J recombinant inbred strains., Bhupinder Khanuja
Intrathymic islet cell transplantation in the NOD mouse: a tolerogenic mechanism?, Daniel E. Krull
Reconstitution of viable motheaten mutant mice with normal hematopoietic progenitor cells., Graciana Lapetina
Computer display of inbreeding dynamics., Victor Lin
Association studies ALP and polymorphisms in the LDL receptor gene., Joyce Meng
CHROmouseSOME: a computer-assisted mouse karyotyping system., Steve L. Philbrick
Genetic factors affecting insulin resistance in DBA/2 and C57BL/Ks mice., S. celeste Posey
Retroviral mutagenesis of murine pre-B cells., Juliet K. Vescio
Submissions from 1991
The Effects of a secondary administration of testosterone on the kinetics of beta-glucuronidase induction., Janet Alter
The Genetic control of parthenogenesis and ovarian teratocarcinogenesis., Gayle Bouchard
Do cyclic AMP response element binding proteins regulate the mitochondrial uncoupling protein gene?, Christopher M.L Bouton
Repopulation in the hematopoietic system- a short term analysis of stem cell dynamics., Ralph J. DiLeone
Characterization of genetic factors for cholesterol gallstone formation in mice., Camille A. Falkner
Characterization of a male sterility mutant caused by the integration of a murine ecotropic leukemia provirus., Charles E. Foulds
The Effects of cryopreservation on the acrosome reaction of mouse spermatozoa., Teca Calcagno Galvao
In vitro growth and maturation of primordial ovarian follicles., Devorah C. Goldman
The Effects of aging on immunological response and oxygen consumption., David C. Gordon
Comparison of alpha thalassemic and wild type erythrocyte survival in wild type hosts., Jennifer M. Greer
The Effects of cryopreservation of mouse sperm on its fertilizability tested by in vitro fertilization., Tobi Groman
Genetic analysis of a mutation causing diverse congenital birth defects., Florence Jean-Louis
The Effects of Ph on W42 and S1., Holly Mason
Gene mapping using PCR and primers of arbitrary nucleotide sequence., Sarah Mutka
Biochemical analysis of minor histocompatibility proteins., Huy Q. Nguyen
Devdritic cell abnormalities in the viable motheaten mutant mouse., Holly Sherburne
Cytokine expression in graft vs. host disease., Tabitha Staley
Molecular analysis of mutant and wildtype canine beta-glucuronidase cDNA., Kimberly E. Stone
Lateralization of function: development of handedness tasks., Nga K. Tang
Development of six genetic eye disorders of the mouse., Jill Tessier
Fetal-specific ankyrin-related proteins and mRNAs in murine erythrocytes., L. Christine Turtzo
The analysis of a transgenic insertion: where's the homozygote?, Frank van Breukelen
Examination of early hematopoietic repopulation., Tracee E. Watkins
The Effects of growth hormone treatment on the body composition of the (lit/lit) mouse., Jacob B. Wills
The Effects of Ph on W42 and S1., Courtney Worcester
Submissions from 1990
Enumeration of minor histocompatibility loci by cytotoxic T cell generation., Sunil Bansal
The Effects of the nurine scid mutation on chromosome recombination and repair. .. Leonard Shultz., Alison Barth
Analysis of blood formation and anemia in embryos carrying the Patch and White-spotting genes., Elizabeth Briggs
Studies characterizing a mouse DHEA sulfotransferaes (Dst) gene and its role in diabetes pathogenesis., Linda M. Call
Quantitation of pneumocystis carinii antigens succeeding anti-Pc immune therapy of scid mice., Eduardo Carrillo
Influence of patch (Ph) upon the fetal blood phenotypes of two white-spotting (W) heterozygotes., Heather Mirth Corbett
The induction of interleukin-6 gene expression in elicited peritoneal macrophages by tumor-derived products., Paul Curthoys
Genetic effects on the change in anti-TNP response with age., Tammy L. Edwards
Isolation and mapping of mouse chromosome a4 anonymous DNA clones., Arleen Gell
A comparison of potential regulatory sequences for the beta-glucuronidase gene in Mus musculus and Mus abotti., Sarah Gillmor
Molecular evolution of the Crya-1 gene in the distal region of the t complex., Jennifer Grenier
Cutaneous dendritic cell populations in the "Flaky-skin Fsn mouse, a mutation resembling psoriasis., Tina Marie Hahn
The interaction of metabolism and aging., Jeffrey M. Heneghan
The expression of EVI-4 in normal tissues of the recombinant inbred BXH-2 mice., Sherry L. Kuchma
The induction of TNF- gene expression in the macrophage cell line P388 D1 by Bh2-1 tumor derived products., Jeffrey Meyerhardt
Molecular comparison of ecotropic murine leukemia viruses isolated from CWD/LeAgl mice., Steven J. Montante
Cytokine mRNA levels in C57BL/6J-lpr/lpr--> +/+ GVH-like syndrome., Jeffrey C. Rathmell
Immunocytochemical localization of tumor necrosis factor- in the lungs of viable motheaten mutant mice., Philip Schaner
Analysis of Hertwig's anemia mutation., Cristan Small
Free radicals in aging: a longitudinal study., Paul Tomlinson
Epidermal kinetics of a murine inherited papulosquamous skin disease resembling psoriasis., Frank van Breukelen
Is the mitochondrial uncoupling protein gene transcribed in white adipose tissue?, Maude White
Submissions from 1989
Generation of a FPS oncogene fusion protein., Jonica Calkins
Chromosomal breakage and repair in severe combined immunodeficient mice., Emma K. Chaput