Students participate in an ongoing research program with the support of an experienced scientific mentor. They develop an independent project, implement their plan, analyze the data, and report the results. At the end of the summer, they present their findings to researchers, other students, and parents.
Submissions from 1987
Identification of histocompatibility loci in newly derived congenic stocks and backcrossed inversion stocks., Linda Tienli Wu
Submissions from 1986
Interaction of proteins with a reducer sequence., Joon Ahn
The role of T helper cells in immune responses against minor and major histocompatibility antigens., Michelle M. Allen
Analysis of African green monkey reducer specificity., Laura Donatella Attardi
I. A correlation of reproductive aging, biological markers and longevity. II. Tail collagen denaturation in recombinant inbred strain for C57BL/6J and BALB/cByJ mice., Stephen C. Bryant
Analysis of H-2 mutants with monoclonal antibodies., Michael P. Bukowski
The nature of the loss of meiotic products in males heterozygous for paracentric inversions., Domenica Carrier
Searches for histocompatibility loci and their linkages using inversion congenics., Donenica Carrier
Specific chromosomal defects in histocytic sarcoma from Hertwig's anemic mice., Mark Carter
Karyotyping of embryonal carcinoma cells., Nancy Fan
Methods for the maximum production of hybridoma antibodies., Sharon L. Flom
Transplantation of bone marrow via placental microinjection to study hemoglobin switching., C. Daniel Frisbie
Methylation of the promoter region of glycerol-3-phosphate dehydrogenase., P. Suzanne Jacks
Southern blot analysis using a photoactivated biotin labelled DNA probe., Jane Libbey
Correlation of glycosylated hemoglobin with collagen aging in mice., Aaron Todd Miller
The effects of superovulation on the development of embryos in culture., Lori S. Newman
Tyrosine hydroxylase maps to murine chromosome 7 within a linkage group conserved in mouse and man., Mark M. Niemann
Thymic homing defects in viable motheaten mutant mice., Glenn Paradis
Gene mapping of 59kDa and 67kDa epidermal keratins., Anthony R. Picarello
Mitotic recombination in the H-2 antigen loss variants., Marie-Blanche N. Tchetgen
Analysis of glycerol-3-phosphate dehydrogenase null mutant., Gillian L. Weiss
Molecular cloning of the platelet fibronectin receptor site., Heather Wilson
The use of ovarian teratomas to construct a meiotic linkage map of chromosome 17 of the house mouse., Hana Yaari
The significance of lymphokines in the immunological function of the DBA/2HA and BXSB mice., Christine Yang
Chromatin determinants of epidermal keratinization., Laura Lee Zenzius
Submissions from 1985
Il-1 production by peritoneal macrophages of tumor- bearing mice., Lorna R. Blanco
Comparison of mouse embryo genotypes in response to cryopreservation protocols., Jessica Boklan
Cryopreservation of hemopoietic stem cells., Jonathan M. Chen
Characterization of DNA sequences in the promoter region of human glycerol-3-phosphate dehydrogenase., Warren Chou
Retrovirus and oncogene expression in normal and tumor tissues of BXH-2 mice., E. Anne Dopson
Analysis of a possible silencer sequence in an African green monkey genomic segment., Barbara L. Hirsch
Diet- and cold-induced thermogenesis in the brown adipose tissue of normal and genetically obese (ob/ob) mice., Robert P. Hoyt
Thermogenesis in the brown adipose tissue of normal (Lean) and genetically obese (ob/ob) mice., Robert P. Hoyt
Genetic analysis of susceptibility to multiple low dose streptozotocin-induced diabetes in two BALB/C sublines., Rebecca A. Lawton
A biochemical analysis of immunoglobulins of viable motheaten mice., Margaret M. McCormack
The effect of geneotype on survival of pre-implantation embryos after ethanol exposure., Elizabeth D. Morgan
Sperm fertility in in vitro fertilization, and chemotaxic interaction between sperm and oocyte., Eric D. Newman
Hemizygosity for cell surface antigens in aging heterozygous murine somatic cells., Nguyen Thi Kin-Anh
Differentiation in mouse myeloid leukemic cells by phorbolesters and lipopolysacharide., Stephanie L. Niznik
Effect of steroid containing diets on cytochrome P450 and hormone sensitive lipase in normal and diabetes mutant mice., Helen Kay Pike
Analysis of cellular sequences flanking intergrated SV40 promoter in embryonal carcinoma cells., Edward Webster Seidel
The measurement of total body fat in living mice by the absorption of cyclopropane., Natalka Antonia Slabyj
The selection of H-2 antigen loss variants from cells which are heterozygous for the t6 chromosome., Daria V. Smith
The strain distribution patterns of genetic markers in recombinant inbred strains that differ in the incidence of spontaneous ovarian teratomas., Michelle R. Stewart
Mechanisms of pulmonary injury in gamma-irradiated recipients of "motheaten" bone marrow., Katherine S. Ullman
HMG protein activatiion of the uncoupling protein gene in brown fat., Michael D. Yanuck
Regulation of gene expression via HMG proteins., Michael D. Yanuck
Submissions from 1984
A comparison of splenocyte populations in C57BL/KsJ db/db (diabetic) and db/+ (normal) mice., Diane R. Blake
The influence of aging on tumor growth., Lawrence S. Bluth
Linkage of an actin-like locus to beta-2-microglobulin on chromosome 2 of the house mouse., Jeffrey L. Crosby
Murine stem cell proliferation and differentiation in vivo and in vitro., Peter Flax
Expression of terminal deoxynucleotidyl transferase and thymus homing capacity of bone marrow cells from viable motheaten mice., Tracy Elizabeth Giordano
Chromatographic analysis or urinary compounds in SWR RI line mice with spontaneous ovarian tumorgenesis of the granulose., Timothy Gormley
The production of intergeneric chimeras from two rodent species., Lora J. Hagemann
Control of virus and oncogene expression in cell cultures of leukemic BXH-2 mice., Paula A. Kataryniak
Selection and characterization of cell lines with reduced and amplified class I H-2 antigen expression and selection for F1 hybrid tumors that survive in homozygous parental mice., Jennifer R. Lederman
Mechanisms involved during amplification of T cell immune responses during tumor rejection., Ann J. Lewis
Epidermal growth factor and insulin binding to liver and ovarian tissue membranes from normal and ovarian tumor- bearing mice., Halina Luszcynska
A genetic analysis of a mouse liver cDNA clone., Heather B. McDonald
The interaction between islet cells and macrophages in vitro., Tracy L. Prosser
Syngeneic and ellogeneic tumor survival in young versus old mice., Elizabeth B. Safran
Dehydroepiandrosterone (DHEA) and lipogenesis., Priscilla W. Sheldon
Spatial abilities in mice selected for differing degrees of cerebral lateralization., Susan E. Snyder
Determination of the effect of injected urethan and of the ter gene on primordial germ cell numbers and incidence of testiculat teratomas., Roger F. Widmann
Submissions from 1983
The effects of age, severe bleeding, and repopulation on erythrocyte lifespans., Tal S. Benschar
The effects of dehydroxyepiandrosteron on the mouse cell line bh2-1., David W. Emery
Assaying for immunodominance effects in skin grafts., Matthew J. Footer
A genetic analysis of 7S RNA sequences in the mouse., Kerin T. Gibbons
The characterization of growth factor independent mutant cell lines., Nina J. Karnovsky
H-2 associated natural resistance to normal bone marrow cells., Amy Kiesche
The effects of melanocyte stimulating hormone on the induction of tyrosinase isozymes in C57BL/6J-Ay/a mice., Carol Lee Leonard
Identification and mapping of the glycerol-3-phosphate dehydrogenase structural genes., Christopher Roland Montanaro
The effect of beta-hydroxyetiocholanolone on streptozotocin induced diabetes in mice., Audra A. Noel
Applications of cognitive maps in mice., Andrew L. Osborn
A new lymphokine from autoimmune viable motheaten mice that promotes B cell differentiation., Deborah H. Paine
Alpha thalassemic mice: identification of fetuses and analysis of gonads and breeding performances., Kathryn A. Pelletier
Hematopoietic stem cell function in viable motheaten mice., K. Kelly Petrison
Characterization of mutant growth factor independent cell lines., Stephanie B. Rubin
Mechanisms of recognition of littermates in mice., Tara Tayyabkhan
Mouse sn-glycerol-3-phosphate dehydrogenase levels and their relationship to hybridizable GPDH mRNA,, Lori A. Wagner
Cyclic nucleotide changes in response to BMF., Phillip L. Wagner
Submissions from 1982
Effect of multiple chromosomal aberrations on fertility in Mus musculus., Roni J. Bollag
The characterization of MOPC 104E cell line., Erie Chao
The biochemical characterization of salivary proteins of inbred mice., Karen M. Davidson
The effect of in vitro culture of mouse pancreatic islets on the prolonation of graft survival in diabetic isogenic and allogenic hosts., Robert F. Davis
The effects of four levels of stress and two diets on the incidence and severity of cardiac calcinosis in DBA/2J mice., Alison K. Hall
Phosphofructokinase and the diabetes/obesity syndrome., Patricia A. Hebert
Regional vasculature in the normal and the tumor bearing muscle of the mouse., Abigail M. Hirschhorn
The development of autoimmunity in viable motheaten mice., Kathleen A. Kaiser
Mechanisms of growth arrest at a unique R (restriction) point in phenotypically normal mouse cell lines., Claire J. Kim
Effects of the PIV caging system on body weight of C57BL/6J male mice., Norma J. LaJoie
Dolichol metabolism in mouse L cell fibroblasts., Paul B. Laub
Immunohistochemical staining for thyrotropin releasing hormone in mouse hypothalamus., Christine A. Lisciotto
Immunological responsiveness of murine strains with single-locus mutations inducing lymphoproliferation and autoimmunity., Amy Mortensen
Chromosome breakage and DNA repair defects in the wasted mutant: a possible model for ataxia telangiectasia., Maureen A. O'Leary
In vitro and in vivo development of preimplantation stage embryos from DBA/2J mice., Abigail Shefer
Control of collagen expression during growth and development., Lisa Stewart