Students participate in an ongoing research program with the support of an experienced scientific mentor. They develop an independent project, implement their plan, analyze the data, and report the results. At the end of the summer, they present their findings to researchers, other students, and parents.
Submissions from 2002
The genetic mapping of a novel mouse muscular dystrophy., Rebecca C. Edgerly
Immunohistological studies of ALMS1 in the mouse: differential expression in obesity mutants., Sarah Eichenberger
The role of growth hormone on development and maturation., Te-Ana Harris
Absence of adhesion molecules ICAM-I and P-selectin accelerates the development of chronic myeloid leukemia induced by BCR/ABL oncogene in mice., Daniel S. Hong
Immunohistochemical characterization of the developing mouse mammary gland., Meggan Hovick
The development of M cells in Peyer's Patches., Tammy Hshieh
Analyzing resistance of B10.D2 mice to insulin-specific diabetogenic CD8+ T cells., Maria Joachim
The transcriptional profile of three mouse chromosomes., Kriten E. Kai
Determining the function of the protein tubby by using the yeast-2-hybrid system., Kristin E. Kalie
Constructing an electronic resource of oncogene information., Charles Kircher
Molecular mechanisms of clozapine-induced hyperglycemia., Kristen Lingley
Gene expression profiles in autoimmune predisposed mice., Lisa L. Ng
Anti-retrovirus immune response and selection of viral variants with distinct pathogenic characteristics., Susannah Parke
Characterization of genes important in preimplantation development., Emily E. Radford
Klebsiella prevention using probiotics., Ricardo Salgado
Mouse mutagenesis database development and mutant characterization of embryonic lethal 15., Carly Satsuma
To oligo or not to oligo? That is the question! Optimizing oligonucleotide arrays using normal and cancerous breast RNA., Julia M. Schmitz
Genetic analysis of the vl mouse., Melissa Spurr
Screening mice for otitis media: assessment of middle ear status in 60 inbred strains of mice., Isaac Tong
Genetic interactions between Jagged1 and Notch1 during embryogenesis., Kate Violette
Finding and testing the candidate genes that determine the high density lipoprotein cholesterol levels in the mouse cross C57BL/6J X NZB/B1NJ., Richard Wagner
Submissions from 2001
The genetic basis of cholelithiasis: a quantitative trait locus (QTL) analysis of CAST/Ei and DBA/2J mouse strains., Laura E. Ayotte
Use of recombinant congenic mouse strains for analysis of diabesity., Victoria Barron
Testing hepatic lipase as a candidate gene for cholesterol gallstone formation in SWR/J and AKR/J inbred strains of mice., Kristin Brubaker
Candidate gene analysis of ALR/Lt. strain's free radical dissipation locus., Thomas Cassidy
Genetic modification of retinal degeneration in tubby mice., Da Chang
Oocyte gene knockouts with a novel technique utilizing BAC's as vectors., Julie Crudele
Optimizing signal amplification in immunohistochemistry and in situ hybridization., Susannah Dickerson
An internship in the Mouse Mutant Resource., Meghan Goff
Gene discovery in the piebald region of mouse chromosome 14., Jackson B. Hewlett
Retroviral recombination and the loss of tumorigenicity., Margaret Hsieh
The effects of hypophysectomy with corticosterone on health span., Elijah Hutchinson
Subclinical infections in immunocompomised mice: a closer look., Lily Johnston
Adapting Lee Silver's book, Mouse Genetics: concepts and applications, for the web., Daniel S. Lawrence
Mechanism of mouse mammary tumor virus neutralization by antibodies produced in I/LnJ mice., Nilah Monnier
A comparison of inositol polyphosphate type II expression in relation to neuronal loss in the weeble mouse., Terri Myers
The genetic mapping of the foot-topper (Ftp) mutation and its modifiers., Jesse J. Mynahan
Genetic analyses of bone strength in inbred strains of mice., Jennifer Mytar
Optimizing detection and sorting of protein secreting cells using GMD and FACs., Kseniya Petrova
Characterization of purkinje cell degeneration in nb/nb mice., Emily Quirion
Characterizing genes important in preimplantation embryo development., Emily E. Radford
Mining for genes important preimplantation embryo development., Emily E. Radford
The mouse phenome project: acoustic startle response and prepulse inhibition., Matthew Reid
Genetically mapping the foot-topper (Ftp) mutation and its modifiers., Amy E. Russell
Phenotyping the chronic proliferative dermatitis (cpdm) mutant mouse., Anne P. Spillane
The chronic proliferative dermatitis locus (cpdm): high resolution mapping., Erin L. Spillane
The role of IFNy in mycobacterium-induced diabetes resistance in the NOD mouse., Brian Stadinski
Endocrine and environmental factors that retard aging in mammals., Dana Swanson
The effect of induced mutations on the B6 background on hematopoietic stem cell surface marker phenotype and hematopoietic stem cell function., Michael TeKippe
The generation of insulin producing, islet type cells from embryonic stem cells., Jessica M. Tierney
Submissions from 2000
Androgen receptor levels in ovarian granulosa cells of granulosa cell tumor susceptible mouse strains., Sudeep Agarwala
Genes supporting neural stem cell population in the adult brain., Rachel L. Allen
Comparing telomere lengths and identifying carriers of trisomy and Sod1 in the Down Syndrome mouse model., Dorothy E. Boles
Yeast two-hybrid analysis of skeletal muscle protein interactions., Catherine Del Vecchio
A novel mechanism of resistance to retroviral infection., Melody G. Duvall
The role of lymphocytes in the organogenesis of Peyer's Patches., Dennis Hsieh
Genetic mapping of a new semi-dominant mouse mutation: Foot-topper (Ftp), Rachel M. Lee
The effects of cryopreservation on the motility of mouse spermatozoa., Andrews Little
The creation of a GAD67 condtional knock-out: a mouse model for the study of insulin dependent diabetes., Peter Madden
Effects of Sod on development in mouse model on Down's Syndrome., Jacki Medin-Ghiraldi
Mapping the insertion site of the Zp3-Cre transgene., Lauren Naliboff
A characterization of myeloid differentiation using flow cytometry., William I. Olver
Design of a knockout construct for an X-linked dynein light chain, P56387, a candidate for primary ciliary dyskinesia., Jill Marie Ricker
Characterization of spontaneous mutants Toothhopper, NM2804, and NM1360., Margaret Samra
The role of the MTHFR gene in cerebellar development., Abigail Shaw
Genetic factors influencing frozen murine spermatozoa viability and function., Michelle A. Theobald
Creation of a bioinformatics resource: designing and implementing a phenotype vocabulary., Kelly E. Tolle
Development of a comparative pathology resource for animal models for human colo-rectal cancer., Pierre Vanden Borre
Characterization of the inferior olive and PNS development in cerebellar deficient folia (cdf) mice. ..SP:Dr. Susan Ackerman. date, Amy B. Vashlishan
Migration and proliferation trends of donor T-lymphocytes in a murine model of minor histocompatibility antigen-induced graft-versus-host disease., Breelyn A. Wilky
Submissions from 1999
Effects of the maternal environment on a mouse model for Down Syndrome., Celia Adelson
Somatic cell genetic mapping of the Ram1 tumor antigen gene., Shreeram Akilesh
Localizing target proteins on mouse tissue samples using mouse monoclonal antibodies., Alecia Ball
Analysis of new Zp3-CRE transgenic lines., Lorraine T. Binns
Bio-informatics, Andrew Borden-Chisholm
Analysis of the Cobblestone assay as an approximation of hematopoietic stem cell function., David Boshko
Mouse / fly homologies on mouse chromosome 2., Douglas A. Calhoun
Gene expression of NZO/HLt mice by Atlas cDNA expression arrays., Kimberly J. Chung
The effects of aging on the telomere length of hematopoietic stem cells in BALB/cByJ and C57BL/6J mice., Paul F. Gugger
Isolation and characterization of a Dynein Light Chain Pseudogene, tctex1PS, of the mouse t complex., Susan E. Habas
Conditional Fas knock-out in pancreatic insulin-producing beta cells., Heather Hartig
A locus responsible for brain development, tailless (Tlx), is proximal to Zfa on mouse chromosome 10 and is located at 28 cM., Mary Catherine Healy
Development of a mouse Trp53 mutation database., Winnie Liang
Effects of cryopreservation on the acrosome and fertilizing ability of mouse spermatozoa., Rita MacCormick
The effects of population size and marker density on power to detect QTL., Genevieve M. Monsees
Genetic analysis of developmental phenotypes in a CASTxC3H intercross., Matthew D. Mrazek
Construction of an retroviral vector containing the Hu APOA-1 Milano gene., Michael A. Newton
The comparative cancer genetics web site., Beto Peliks
CD4 molecules lacking p56lck binding site promote T cell recognition of MHC class I., Stephen Poon
A high-resolution map of the piebald(s) deletion complex on chromosome 14., Jeffrey Roix
Molecular approaches to understanding retinal degenerations., Philip C. Rosenstiel
Examination of dying granule and purkinje cells in harlequin and sticky mutant mice., Marlies Rossman
A comparison of sperm osmotic tolerances between C57BL/6J and B6D2F1., Sarah Rubin
Looking for new alleles in mouse mutants with absence epilepsies., Valeria Smith
Mechanisms of tumorigenesis induced by simple retroviruses., Stephanie Turner
Guidelines for developing staining panels for multi-parametric fluorescent analysis., Kristin Vekasi
Knocking-out the H13 gene., Travis Walls