Students participate in an ongoing research program with the support of an experienced scientific mentor. They develop an independent project, implement their plan, analyze the data, and report the results. At the end of the summer, they present their findings to researchers, other students, and parents.
Submissions from 2007
Trans-acting genes mediate the activity and sex specificity of recombination hotspots in mice, Caleb Dresser
Probing mechanism of neurodevelopment using novel mouse mutant, Tiffany Hammond
Jaxbook, Chenxing Han
The roles of Nmyc (Mycn) in the Ph+ leukemias, Nataliya Ilyashenko
Genetic regulation of traits of female reproductive history, Hope Kronman
RF11: Developing a mouse model for renal failure, Paul L. Maitland-McKinley
Web-interface database for comparative cancer quantitative trait loci (QTLs), Victoria Massie
Examination and identification of Lat2 as a candidate gene of the metabolic syndrome in Nmf15 mice, Jameson K. Mattingly
Towards a molecular and genetic understanding of aqueous humor drainage in glaucoma, Heather McLaughlin
The metabolic treadmill: a screening tool to verify differences in mice with neuromuscular, metabolic, and cardiovascular disorders, Joseph Mercado
Candidate gene identification of the Gct4 and Gct6 granulosa cell (GC) tumor susceptibility loci, Katelyn Michaud
The effect of myostatin blockage on MDM mouse skeletal muscle, Seanna Pieper-Jordan
Identifying and testing metabolic pathway regulation genes on mouse chromosomes 3 and 8, Renita Polk
Factors controlling intraocular pressure elevation, Jenny Rempel
Using a chemically defined media to freeze mouse sperm, Pamela A. Reyes
The effects of four sub strains of Klebsiella oxytoca in C57BL/6J mice, Sandra Schleier
Genomic mapping and phenotypic characterization of the mutant mouse strain CFENU4/"Gutsy", Stephanie Siegmund
The role of the blood ocular barrier in glaucoma and neuroprotection, Beryl Swanson
Identification of network motifs in lung disease, Cecily Swinburne
Biological relevance of the three-cell mouse embryo, Nicolas E. Tokas
Ontological modeling for knowledge representation of lung disease, Esther Uduehi
The role of NF-kappaB in BCR-ABL leukemogenesis, Cynthia Wei
A new model of T cell quiescence, Timothy C. Wentworth
The gene expression response to high-fat diet, David Witmer
Exploring relationships between and within different classes of "gene deserts" in the mouse genome, Cheryl Zapata
Characteristics of 4601 and nm4120, mutants for retinal degeneration, Zhen Zhang
Submissions from 2006
Characterizing a potentially new neurological mutation involving shaking., Anselm Beach
IL-21 and SLE., Shauna Bennett
Camp Jax: a summer of discovery., Haley Bridger
Bioinformatics approaches for candidate gene analysis., Dorian Britt
The "thrombocytopenia and cardiomyopathy" (trac) mutation: effects of phytosterols on normal platelet production, Alex S. Burn
Integration of the gene ontology and human disease description., Curt Christian
Aging and metabolism: the role of neuropeptide Y., Elizabeth Clore
Mouse hearing models: genetic mapping and ear pathology., Leah A. Davis
Breast cancer stem cells., Zinaida Dedeic
Does cryopreservation decapacitate C57BL/6J sperm?, Katherine Leah Gassman
Analysis of iNKT cells in NOD and diabetes resistant NOD MHC congenics., Nyssa M. Gatcombe
Candidate genes affecting HDL levels on chromosome 15., Bartlett IV Harwood
In vivo anatomy and physiology of mouse respiratory system., Elan Jones
ABCG2, ID2, and ID4: cancer stem cells and cancer cell proliferation., Daniel Kelmenson
Positional cloning of the sjd mutation., Alexandra Landry
The role of PPARy in adipogenesis., Suzanne McCluskey
Testing candidate genes for HDL., Katherine McKelvey
Comparative genetics database for the study of female infertility., Grace Olamijulo
Mining metabolic pathway data from gene ontology annotation., Michael Petkov
Mid1 slternative promoters in B-cell proliferation and systemic lupus erythematosis., Harsha Prabhala
Genetic characterization of the cataract shionogi (Cts) mouse., Eric Reid
Genetic differences in cellular proliferative ability of ten day old embryos., Felicia R. Reid
Visualizing and quantifying events between the 2-cell and 4-cell stages of early mouse development., Nicole Seda
Molecular regulation of Kit oncogene in bone marrow stem cells., Yi-Meng Tan
The role of Artemis in suppression of chromosome instability at common fragile sites., Laura C. Titus
Visualization of genome organization in the laboratory mouse., Arielle M. Torres
Analyzing gene expression in mouse strains., Luis P. Zapata
Role of gene activity on nuclear organization of chromosome clusters and deserts., Jennifer W. Zhan
Submissions from 2005
Comparative genomics of localization elements in 3' untranslated region sequences., Alexandra E. Albert
Exploring the role of nuclear architecture in chromosome translocation patterns., Anthony R. Britt
The real science., Kristopher Carlson
Identifying novel genes regulating plasma high-density lipoprotein cholesterol levels., Yu-Hwei Chou
Promoting the meiotic division of male germ cells in vitro., Jessica J. Deane
Immune cell demographics in lipodystrophic adipose tissue., Alison Dempsey
Comparison of 3-D volume measurement by microCT and high frequency ultrasound using the kidney as a model organ., David Len Elion
Hematopoietic and non-hematopoietic effects of CD38 and/or ART2 deficiency in type 1 diabetes., Bethany Evans
Genetic regulation of tail skin fibroblast aging in vitro., Katherine E. Gaire
Mechanisms of alpha-GalCer inhibition of type 1 diabetes in NOD mice., Alexandra E. Grier
Cutaneous immunomolecular pathological phenotyping of mutant mice., Sarah M. Hamilton
Exploring gene duplication on chromosome 1 to elucidate functional organization., Niculin Herz
Growth hormone deficiency and abnormal carbohydrate metabolic aging in the Little mice (Ghrhrlit/Ghrhrlit)., Diana Kombe
Fine mapping of two novel deafness mutations in mice., Gretchen Lewis
Ontological modeling of a metabolic disease., Daniel Lieber
Creating a leukodystrophy database., Farre Nixon
Analysis of the effects of oxidative stress on forebrain development., Katie O'Hara
What is the interaction between the W57 and W42 mutations?, Nicole Rothenheber
Identifying HDL genes in chromosome 8 QTLs using B6 and A/J., Kristin Russell
High-density sex-specific recombination mapping of a 25 megabase region on mouse chromosome 1., Kathryn Sawyer
The voltage dependent calcium channel and its association with absence epilepsy., Kayle Shapero
Novel software for flexible data analysis and visualization in genomics., Troy Shapiro
Interplays between mouse mammary tumor virus and its host., Zachary Smith
Exploring novel mechanisms in a mouse model of rostrocaudal muscular dystrophy., Laura Supkoff
Investigation of isolated cells from a mouse model of mammary cancer., Hannah M. Tetreault
Characterization of phenotype of mutant gene causing meiosis failure of mouse spermatocytes., Jenny Tiskus
nm2608A, a naturally arising mouse model for human autosomal recessive achromatopsia 2., Xin Wang
The roles of adhesion molecules in leukemia., Zhu Wang
Feedback regulation of the adaptive immune response by fas-induced apoptosis of APCs., Jessica Watson
Mouse models of retinal degeneration: NMF 247 and 240., Carrie Whiting
High resolution genetic mapping and characterization of the ENU induced mouse obesity mutation NMF15., Mariaah Williams
IFN-y dependent resistance mechanism of I/LnJ mice to retroviruses., Leonid Yurkovetskiy
Submissions from 2004
Using bioinformatics approaches to catalyze disease gene discovery., Ayodele Adesanya
Susceptibility factors for glaucomatous neurodegeneration., Joe Barter
A network approach to cancer genetics: visual portrayal of cancer pathways with genetic database references., Rebecca A. Barter
A network approach to cancer genetics: visual portrayal of cancer pathways with genetic database references., Rebecca A. Barter
What I did on my summer vacation. 2004 Summer Student research summaries for the non-scientist., Amber Bauer
Exploring common features of gene cluster and desert nuclear organization and their links to gene expression., Laura Brenner
Assessing gene ontology annotation consistancy., Megan E. Campbell
Uncovering the role of the agrin protein in Alzheimer's disease neurodegeneration., Constantin Chikando
Mechanism for tumor induction by mouse mammary tumor virus., Silas Culver
Temporal and spatial expression of ALMS1 protein in alms1 gene trap mice., Erika Cyr