Students participate in an ongoing research program with the support of an experienced scientific mentor. They develop an independent project, implement their plan, analyze the data, and report the results. At the end of the summer, they present their findings to researchers, other students, and parents.
Submissions from 2005
Genetic regulation of tail skin fibroblast aging in vitro., Katherine E. Gaire
Mechanisms of alpha-GalCer inhibition of type 1 diabetes in NOD mice., Alexandra E. Grier
Cutaneous immunomolecular pathological phenotyping of mutant mice., Sarah M. Hamilton
Exploring gene duplication on chromosome 1 to elucidate functional organization., Niculin Herz
Growth hormone deficiency and abnormal carbohydrate metabolic aging in the Little mice (Ghrhrlit/Ghrhrlit)., Diana Kombe
Fine mapping of two novel deafness mutations in mice., Gretchen Lewis
Ontological modeling of a metabolic disease., Daniel Lieber
Creating a leukodystrophy database., Farre Nixon
Analysis of the effects of oxidative stress on forebrain development., Katie O'Hara
What is the interaction between the W57 and W42 mutations?, Nicole Rothenheber
Identifying HDL genes in chromosome 8 QTLs using B6 and A/J., Kristin Russell
High-density sex-specific recombination mapping of a 25 megabase region on mouse chromosome 1., Kathryn Sawyer
The voltage dependent calcium channel and its association with absence epilepsy., Kayle Shapero
Novel software for flexible data analysis and visualization in genomics., Troy Shapiro
Interplays between mouse mammary tumor virus and its host., Zachary Smith
Exploring novel mechanisms in a mouse model of rostrocaudal muscular dystrophy., Laura Supkoff
Investigation of isolated cells from a mouse model of mammary cancer., Hannah M. Tetreault
Characterization of phenotype of mutant gene causing meiosis failure of mouse spermatocytes., Jenny Tiskus
nm2608A, a naturally arising mouse model for human autosomal recessive achromatopsia 2., Xin Wang
The roles of adhesion molecules in leukemia., Zhu Wang
Feedback regulation of the adaptive immune response by fas-induced apoptosis of APCs., Jessica Watson
Mouse models of retinal degeneration: NMF 247 and 240., Carrie Whiting
High resolution genetic mapping and characterization of the ENU induced mouse obesity mutation NMF15., Mariaah Williams
IFN-y dependent resistance mechanism of I/LnJ mice to retroviruses., Leonid Yurkovetskiy
Submissions from 2004
Using bioinformatics approaches to catalyze disease gene discovery., Ayodele Adesanya
Susceptibility factors for glaucomatous neurodegeneration., Joe Barter
A network approach to cancer genetics: visual portrayal of cancer pathways with genetic database references., Rebecca A. Barter
A network approach to cancer genetics: visual portrayal of cancer pathways with genetic database references., Rebecca A. Barter
What I did on my summer vacation. 2004 Summer Student research summaries for the non-scientist., Amber Bauer
Exploring common features of gene cluster and desert nuclear organization and their links to gene expression., Laura Brenner
Assessing gene ontology annotation consistancy., Megan E. Campbell
Uncovering the role of the agrin protein in Alzheimer's disease neurodegeneration., Constantin Chikando
Mechanism for tumor induction by mouse mammary tumor virus., Silas Culver
Temporal and spatial expression of ALMS1 protein in alms1 gene trap mice., Erika Cyr
The role of Sf1 in gonadal sex determination in C57BL/6J (B6) mice., Jane Ferguson
Comparison of accelerated versus retarded diabetes in two genetically modified stocks of NOD/Lt mice., Nathan A. Harbacek
The role of growth hormone on aging., Bomopregha A. Julius
Genetic studies of deafness mutations., Hannah L. Kiernes
Assessment of analgesics in mice., Ebony King
Genetics of a mutation that leads to hearing loss., Julie A. Linden
Spontaneous hematological mutations in mice., Gina Luchini
Localization of mitochondria during early development of the mouse embryo., Jacquelyn Masse
Gene identification of the spontaneous Fitfull mutation., Amanda Muscat
Identification of homologous 3'-untranslated region sequences and characterization of conserved regulatory elements., Jill M. Recla
Genetic mutations linked with mouse ear infections., Whitney A. Reid
The normoblastis mutation in mice: investigation of neurological deficits in the nb/nb cerebellum., Jesse Sayers
Bone formation in B6.C3H-9 congenic strain with male specific reduction in bone mineral density (BMD)., Carolyn C. Schook
Bioinformatics search for stem cell regulatory mechanisms., Michael Segal
Detecting helicobacter spp. by fecal PCR analysis., Mihaela Senek
Identifying genetic polymorphisms that contribute to kidney disease., Caitlin Stanton
Roles of cyclin D1 in BCR/ABL signaling., Sarah J. Swerdlow
Positional cloning of a novel neuromuscular mutation., Ashley Phillips Taylor
Mapping obesity genes., Alicia Kim Vose
The genetic analysis of non-alcoholic fatty liver disease., Abby Winterberg
Understanding B10.D2 mice's resistance to diabetogenic IS-CD8+ T cells., Carol Yan
Identifying and mapping the mutant allele for retinal degeneration in nm3448., Jiyang Zhang
Submissions from 2003
Characterization of autoimmune mediated myositis in the NOD.IFNyRbetaTg mouse., Ashley R. Bamman
The nature of alternative polyadenylation sites in yeast., Seema Bhopale
Genetic basis and phenotypic effects of a novel mouse muscular dystrophy and limb developmental mutation., Michael E. Birnbaum
Mrf2 as a candidate gene for atherosclerosis susceptibility in mice., Alisha Biser
Erythroid ankyrin (Ank1) gene expression in C2C12 myoblasts during differentiation in culture: usage of alternative 3' UTRs., Sara A. Bumgardner
Developmental rates predict longevity in genetically heterogeneous mice., Teressa Egeler
Post-doc housing: environmentally friendly solutions to housing and childcare needs on MDI., Emily Eller
Expression of WNT-beta-catenin signaling pathway members in oocytes and preimplantation embryos., Bryce Haac
Bioinformatics of disease., David Haluska
Pathogenesis of alopecia and ulcerative dermatitis in C57BL/6J mice., Jennifer Hayford
Multiparametric evaluation and enumeration of murine hematopoietic stem cells in various strains., Karen Hussein
Investigation of FcRn induction by different stimuli and its importance on the half life of immunoglobulin G., Eda Kapinova
Positional cloning of a novel mouse neuromuscular mutation., Alexandra L. Kieffer
Real-time PCR analysis of gene expression in adipose tissue of obese tubby mice., Stephanie Liu
Gene expression in retinal development., Rebecca C. Lock
Metabolic function in three strains of neonatal diabetic mouse models., Anne MacNeil
Mapping the viral infectivity controller gene conferring resistance to mouse mammary tumor virus infection in I/LnJ mice., Mary Mechetner
The role of gene "Deserts" in chromosome structure., Kelly R. Molloy
Fine mapping of MHC linked gene(s) conferring resistance to IS-CD8+ cell induced diabetes., Ian Monk
Searching QTLs by gene expression: analysis of diabesity., William I. Olver
Identifying bacteria and characterizing pathology of Otitis medica in mice., Adalme Pena
Mapping a gene influencing B cell percentages in blood and spleen cells., Tiffany Pinchinat
Molecular mechanisms of leukemogenesis induced by two human oncogenes: BCR/ABL and TEL/PDGFbetaR in a murine model., Camden Ramsay
Identifying the gene for Hdlq7, a quantitative trait locus the regulates high density lipoprotein cholesterol concentrations in mice., Regina L. Readling
Genetic and phenotypic analysis of Jitterbug (jbg), a novel spontaneous mutation causing deafness and vestibular dysfunction in mice., Katherine W. Saylor
Absence of TNF receptors may decrease diabetic nephropathy., Max Stem
ALMS1: mutational analysis in humans and subcellular localization in TallyHo mice., Vanessa J. Sterling
Capturing age-retarding alleles through selection for longevity., Kathryn L. Stewart
Creation of an online relational database housing human and mouse cancer genes., Andrew J. Sweatt
Positional cloning of the Pintail gene., Edward George Tailfeathers
Software for in silico positional candidate analysis., Brad Witham
Role of the virally encoded gag gene in mouse mammary tumor virus-induced mammary tumors., Annie Zhang
Submissions from 2002
INVESTIGATION OF PHOSPHATIDYLETHANOLAMINE N-METHYL TRANSFERASE EXPRESSION AS A FACTOR IN TYPE II DIABETES., ADEWOLE S. ADAMSON
A study of an atypical small isoform of the cytoskeletal protein ankyrin in the heart., Jennifer Baker
Investigating the biological pathway through which Nr2e3 functions., Joemma Berberich
Mapping of a gene regulating B lymphocyte proportions in mouse peripheral blood., Emily R. Cuthbertson
Defective B cell tolerance mechanisms in the NOD mouse., Joseph William Dombrowsky
Neural stem cells in MRL and CD-1 mice., Nathan Dorr
Quantitative trait locus analysis for cholesterol gallstone susceptibility and phenotypic evaluation of candidate genes using 129S1/SvImJ and CAST/Ei inbred mouse strains., Bethany L. Dumont
Evaluation of pheromonal and hormonal treatments for the synchronization of estrus in mice., Jared J. Eddy