Students participate in an ongoing research program with the support of an experienced scientific mentor. They develop an independent project, implement their plan, analyze the data, and report the results. At the end of the summer, they present their findings to researchers, other students, and parents.
Submissions from 2011
In vivo imaging of neuronal circuit change in mouse models of Amyotrophic Lateral Sclerosis (ALS)., Jennifer Zhu
Submissions from 2010
Data integration and analysis of drug and alcohol dependence related genes: an application of ODE., Amanda Ackovitz
Autism speaks: enhancing MGI's ontologies and annotations to improve autism research., Christopher Carr
The relation of polycomb proteins with 3D structure in the nucleus., Sarah Castor
Deciphering the molecular basis of a mutation in the Ptpn6 gene., William Cheng
Using ontological discovery environment to discover mechanisms of glaucoma in gene expression profiling data., Keith Funkhouser
Finding the genetic mutation causing high levels of circulating plasma triglycerides in HLB505 mouse model., Alexandra Greene
Hearing & genetics: mapping and pathology of mouse mutations causing hearing loss., Allison Hanaford
Localization of DSCAMs and interacting proteins in the developing retina., Lesley Hill
Spatial gene associations in ES cell nuclei., Emily Hollenbeck
Identification of gut microbes associated with human intestinal disease., Ashley B. Hunt
The role of heat shock factor 1 and heat shock protein 72 in Jun N-terminal kinase-mediated cell death., Aiyang Jiang
QGV: a QTL and GWAS results viewing and manipulation tool., Michael C. Jones
Creation of an RNA isoform visualization toolkit., Lukas Jordan
Investigating the role of astrocytes in glaucoma., Keren Katorza
The derivation of embryonic stem cells from a novelmouse modelof amyotrophic lateral sclerosis., Kate Macina
Cellular dynamics of the three to eight-cell mouse embryo., Adriana Martinez-Betancourt
Mapping recombination hotspots in the C57BL/6J-Chr1 PWD/PhJ X C57BL/6J mouse cross to find evidence of genetic regulation., Alison Mehlhorn
Notch signaling in medulloblastoma., Emily E. Miller
Dissecting NKT-dendritic cell interactive control of type-1 diabetes., Rebecca O'Donnell
The importance of microarray data in predicting complex disease phenotypes compared to genotype data in soybeans (Glycine max)., Olutoyosi. Oyelowo
Exploring the effect of a high fat diet on alternative transcript abundance., Nurit Pereg-Azouz
Alternate mRNA processing and cancer: a quantitative microarray study., Weitao Qiang
The genetics of lung development and disease., Jennifer Rodriguez
Investigating neuroprotective therapies in mice with glaucoma., Eden Rouse
Characterizing the molecular features of medulloblastoma subtypes., Brad Rybinski
Characterizing a gene variant that extends lifespan in mice., Paul T. Smith
Using mouse models to investigate the genetic pathways of multiple sclerosis (MS)., India Stewart
Inflammatory cell populations and antigenic proteins in the testis of sertoli cell androgen receptor knockout (SCARKO) mice., Chloe J. Taub
Genetic factors controlling intraocular pressure elevation., Patricia J. Troy
The effect of MK2 and Rock2 on leukemia tumor cells., Alex Zannos
Submissions from 2009
Benefits and barriers of manipulating the iNKT-cell dendritic cell axis for treatment of type-1 diabetes., Shannon T. Bean
Transcriptional effects of Ptgs2 exchange in liver and adipose., Alan Bohn
Characterization of Ccr5 deficiency in the NOD-scid IL2rynull Ccr5null mouse strain., Erica Brown
Protein-protein interactions in the epileptic fitful mouse mutant., Alexandra Buckley
Mapping genes responsible for high HDL levels in ENU-mutagenized C57BL/6J mice., Helen Cha
Comparison of genes and biological processes in conserved and non-conserved gene deserts., Minna Chen
Constructing and optimizing a predictive model for polyadenylation sites in mice., Lauren M. Chircus
7q36 and genome stability: investigating Xrcc2., Eliot Coffey
Immunohistochemical screen for new cell-type specific marker proteins in the murine retina., Kevin Conway
Lupus in a murine model., Mario Robert Crisalli
Finding the single gene mutation responsible for causing tachycardia in an ENU mutant., Amy E. Dalrymple
Characterization of Cre driver lines for neurobiology research., Katelyn DeNegre
The role claudin-3 in blood-testis barrier reorganization., Jing Fan
Improved position-dependent sequence motif characterization and automated transfer for gene prediction., Justin Gardin
Characterization of Unc5d netrin receptor in developing mouse brain and retina., Jude Gonsalves
FcRn : The antibody receptor of the immune system., Yonas Hailu
Development and reconstruction of the neuronal cell types in the cell ontology., Morgan V. Hightshoe
A systems biology approach to the genetic dissection of obesity in a C57BL/6J x C3H/HeJ F2 mouse cross., Justin Huang
Locating Lepr db/9J mutation in female and male mice., Aleah Kenner
Identifying quantitative trait loci for hip axis geometry phenotypes in C57BL/6J X CAST/EiJ inbred mice., Amy Marie Michaud
Elucidating the function of the gene adducing 3 (gamma) in T-cell acute lymphoblastic leukemia., Ceslee D. Montgomery
Genomic instability in hematopoietic stem cells in B6 and BALB mice., Olivia Moody
Development of mouse models for hereditary deafness and gene expression analysis and distribution., Bailey C. Peck
Predicting associations between genes and phenotypes using Bayesian networks., Sheetal Rajagopal
A mouse model for the effects of Tenofovir on vitamin D pathway, calcium homeostasis, and bone mineral density in HIV patients., Jacqueline Rodriguez
Building a cell cycle ontology for mouse based on the Mouse Genome Informatics Database., David Robert Smith
Discovering new mouse models for female reproductive diseases., Mandesa Smith
Investigating sodium channel variants for genetic modifers in epileptic mice.l, Michael Stanley
Discovery of genes that contribute to normal lung development., Isaac St. John
The effect of Pank3 on HDL levels in mice., Lidia Valdes
The effect of the Little mutation (lit/lit) on the activation state of the mTor pathway., Yiftusira Girma Wondimu
Investigating a mutant mouse strain with progressive neurodegeneration., Matthew Younger
Submissions from 2008
Verification of Pank3 as a candidate gene underlying a mouse HDL QTL., Sarah Amend
In comparison to B6, is faster aging of hematopoietic stem cell function in BALB/cBy due to increased susceptibility to genomic instability?, Harmony B. Bell
The joy of science, Jacqueline Boytim
Quantitative allometric description and genetic analysis of a novel skeletal mutant, rhizomelia (rzm), Matthew Chroust
Quantitative trait loci analysis of blood pressure in an eight intercross mouse study, Marion Elizabeth Deerhake
A new genetic system for mammalian cells. Testing for the presence of the interferon system, Sarah DeVos
Functional trends among genes associated with desert regions., Alex Ellison
Understanding the role of Timp1, Ereg, Tnc, and Vcan in glaucoma, Christopher J. Ferreira
microRNA expression pattern in normal mouse lung development and cancer, Kevin Hawkins
Quantitative trait loci analysis of kidney weight in an eight intercross mouse study., Ryan Keating
Complex complexities, William Joseph Kornahrens
Characterization of the repro8 infertility phenotype in male mice, Kaitlin Laws
Genetic background effects on phenotypes of neuro-muscular disease models: with a concentration on proximal spinal muscular atrophy, Beiyun Caitlin Liu
Claudin-3 and claudin-11 localization in sertoli cell tight junctions, Gideon Logan
Phenotypic analysis of mice heterozygous for Trim28, Kai Alexandra Mills
Identification of proteins modified by SUMO during male germ cell development, Constantine Monzidelis
Characterization of a meiotic recombination trans-acting factor, Allyson Palmer
nm6599, a new mouse model for human CSNB2, Shiyi Pang
The use of immunohistochemistry to characterize the role of dicer in the mouse male germline, Gabrielle Puente
Mapping the mutation underlying albuminuria in the Rn/11 line, Ruksana Rangwala
Factors controlling intraocular pressure elevation, Patti Scarff
Brain cancer stem cell genes, Natasha Shylo
A new molecular screen for Akt/TOR activation, Laura L. Smith
A phenotypic analysis of Pax3 lineage notch1 conditionally null mice, Gregory L. Sousa
3D charachterization of the synaptonemal complex on the 100 NM scale, Emily Suter
Bioinformatics as a tool for finding candidate genes for quantitative trait loci, Judith Vasquez
Validation of humanized mouse models, Jennifer Margaret Wagner
Mining the mouse phenome database (MPD) to find candidate modifier genes: oles revealed for serum IGF-1 levels and FOXO3 inactivation in nmd mice, Jennifer Whiting
Determining the origin of cardiac progenitor cells repopulating the heart, Eric Y. Zhang
Submissions from 2007
Determination of the functions and molecular mechanisms of Id2 and Id4 in brain development, Kasima Brown
Genetic regulation of bone mineral density in mouse inbred strains, LaRae Brown
Genetic and phenotype mapping of a novel neurodegenerative mutation and characterization of its pathology, Sylvia K. Dasi
Genetic modulation of immune system function in BXSB-Yaa mice, Caitlin Deane
Identification of linkage disequilibrium domains in inbred mice, Alexandra Denby