Students participate in an ongoing research program with the support of an experienced scientific mentor. They develop an independent project, implement their plan, analyze the data, and report the results. At the end of the summer, they present their findings to researchers, other students, and parents.
Submissions from 2009
The effect of the Little mutation (lit/lit) on the activation state of the mTor pathway., Yiftusira Girma Wondimu
Investigating a mutant mouse strain with progressive neurodegeneration., Matthew Younger
Submissions from 2008
Verification of Pank3 as a candidate gene underlying a mouse HDL QTL., Sarah Amend
In comparison to B6, is faster aging of hematopoietic stem cell function in BALB/cBy due to increased susceptibility to genomic instability?, Harmony B. Bell
The joy of science, Jacqueline Boytim
Quantitative allometric description and genetic analysis of a novel skeletal mutant, rhizomelia (rzm), Matthew Chroust
Quantitative trait loci analysis of blood pressure in an eight intercross mouse study, Marion Elizabeth Deerhake
A new genetic system for mammalian cells. Testing for the presence of the interferon system, Sarah DeVos
Functional trends among genes associated with desert regions., Alex Ellison
Understanding the role of Timp1, Ereg, Tnc, and Vcan in glaucoma, Christopher J. Ferreira
microRNA expression pattern in normal mouse lung development and cancer, Kevin Hawkins
Quantitative trait loci analysis of kidney weight in an eight intercross mouse study., Ryan Keating
Complex complexities, William Joseph Kornahrens
Characterization of the repro8 infertility phenotype in male mice, Kaitlin Laws
Genetic background effects on phenotypes of neuro-muscular disease models: with a concentration on proximal spinal muscular atrophy, Beiyun Caitlin Liu
Claudin-3 and claudin-11 localization in sertoli cell tight junctions, Gideon Logan
Phenotypic analysis of mice heterozygous for Trim28, Kai Alexandra Mills
Identification of proteins modified by SUMO during male germ cell development, Constantine Monzidelis
Characterization of a meiotic recombination trans-acting factor, Allyson Palmer
nm6599, a new mouse model for human CSNB2, Shiyi Pang
The use of immunohistochemistry to characterize the role of dicer in the mouse male germline, Gabrielle Puente
Mapping the mutation underlying albuminuria in the Rn/11 line, Ruksana Rangwala
Factors controlling intraocular pressure elevation, Patti Scarff
Brain cancer stem cell genes, Natasha Shylo
A new molecular screen for Akt/TOR activation, Laura L. Smith
A phenotypic analysis of Pax3 lineage notch1 conditionally null mice, Gregory L. Sousa
3D charachterization of the synaptonemal complex on the 100 NM scale, Emily Suter
Bioinformatics as a tool for finding candidate genes for quantitative trait loci, Judith Vasquez
Validation of humanized mouse models, Jennifer Margaret Wagner
Mining the mouse phenome database (MPD) to find candidate modifier genes: oles revealed for serum IGF-1 levels and FOXO3 inactivation in nmd mice, Jennifer Whiting
Determining the origin of cardiac progenitor cells repopulating the heart, Eric Y. Zhang
Submissions from 2007
Determination of the functions and molecular mechanisms of Id2 and Id4 in brain development, Kasima Brown
Genetic regulation of bone mineral density in mouse inbred strains, LaRae Brown
Genetic and phenotype mapping of a novel neurodegenerative mutation and characterization of its pathology, Sylvia K. Dasi
Genetic modulation of immune system function in BXSB-Yaa mice, Caitlin Deane
Identification of linkage disequilibrium domains in inbred mice, Alexandra Denby
Trans-acting genes mediate the activity and sex specificity of recombination hotspots in mice, Caleb Dresser
Probing mechanism of neurodevelopment using novel mouse mutant, Tiffany Hammond
Jaxbook, Chenxing Han
The roles of Nmyc (Mycn) in the Ph+ leukemias, Nataliya Ilyashenko
Genetic regulation of traits of female reproductive history, Hope Kronman
RF11: Developing a mouse model for renal failure, Paul L. Maitland-McKinley
Web-interface database for comparative cancer quantitative trait loci (QTLs), Victoria Massie
Examination and identification of Lat2 as a candidate gene of the metabolic syndrome in Nmf15 mice, Jameson K. Mattingly
Towards a molecular and genetic understanding of aqueous humor drainage in glaucoma, Heather McLaughlin
The metabolic treadmill: a screening tool to verify differences in mice with neuromuscular, metabolic, and cardiovascular disorders, Joseph Mercado
Candidate gene identification of the Gct4 and Gct6 granulosa cell (GC) tumor susceptibility loci, Katelyn Michaud
The effect of myostatin blockage on MDM mouse skeletal muscle, Seanna Pieper-Jordan
Identifying and testing metabolic pathway regulation genes on mouse chromosomes 3 and 8, Renita Polk
Factors controlling intraocular pressure elevation, Jenny Rempel
Using a chemically defined media to freeze mouse sperm, Pamela A. Reyes
The effects of four sub strains of Klebsiella oxytoca in C57BL/6J mice, Sandra Schleier
Genomic mapping and phenotypic characterization of the mutant mouse strain CFENU4/"Gutsy", Stephanie Siegmund
The role of the blood ocular barrier in glaucoma and neuroprotection, Beryl Swanson
Identification of network motifs in lung disease, Cecily Swinburne
Biological relevance of the three-cell mouse embryo, Nicolas E. Tokas
Ontological modeling for knowledge representation of lung disease, Esther Uduehi
The role of NF-kappaB in BCR-ABL leukemogenesis, Cynthia Wei
A new model of T cell quiescence, Timothy C. Wentworth
The gene expression response to high-fat diet, David Witmer
Exploring relationships between and within different classes of "gene deserts" in the mouse genome, Cheryl Zapata
Characteristics of 4601 and nm4120, mutants for retinal degeneration, Zhen Zhang
Submissions from 2006
Characterizing a potentially new neurological mutation involving shaking., Anselm Beach
IL-21 and SLE., Shauna Bennett
Camp Jax: a summer of discovery., Haley Bridger
Bioinformatics approaches for candidate gene analysis., Dorian Britt
The "thrombocytopenia and cardiomyopathy" (trac) mutation: effects of phytosterols on normal platelet production, Alex S. Burn
Integration of the gene ontology and human disease description., Curt Christian
Aging and metabolism: the role of neuropeptide Y., Elizabeth Clore
Mouse hearing models: genetic mapping and ear pathology., Leah A. Davis
Breast cancer stem cells., Zinaida Dedeic
Does cryopreservation decapacitate C57BL/6J sperm?, Katherine Leah Gassman
Analysis of iNKT cells in NOD and diabetes resistant NOD MHC congenics., Nyssa M. Gatcombe
Candidate genes affecting HDL levels on chromosome 15., Bartlett IV Harwood
In vivo anatomy and physiology of mouse respiratory system., Elan Jones
ABCG2, ID2, and ID4: cancer stem cells and cancer cell proliferation., Daniel Kelmenson
Positional cloning of the sjd mutation., Alexandra Landry
The role of PPARy in adipogenesis., Suzanne McCluskey
Testing candidate genes for HDL., Katherine McKelvey
Comparative genetics database for the study of female infertility., Grace Olamijulo
Mining metabolic pathway data from gene ontology annotation., Michael Petkov
Mid1 slternative promoters in B-cell proliferation and systemic lupus erythematosis., Harsha Prabhala
Genetic characterization of the cataract shionogi (Cts) mouse., Eric Reid
Genetic differences in cellular proliferative ability of ten day old embryos., Felicia R. Reid
Visualizing and quantifying events between the 2-cell and 4-cell stages of early mouse development., Nicole Seda
Molecular regulation of Kit oncogene in bone marrow stem cells., Yi-Meng Tan
The role of Artemis in suppression of chromosome instability at common fragile sites., Laura C. Titus
Visualization of genome organization in the laboratory mouse., Arielle M. Torres
Analyzing gene expression in mouse strains., Luis P. Zapata
Role of gene activity on nuclear organization of chromosome clusters and deserts., Jennifer W. Zhan
Submissions from 2005
Comparative genomics of localization elements in 3' untranslated region sequences., Alexandra E. Albert
Exploring the role of nuclear architecture in chromosome translocation patterns., Anthony R. Britt
The real science., Kristopher Carlson
Identifying novel genes regulating plasma high-density lipoprotein cholesterol levels., Yu-Hwei Chou
Promoting the meiotic division of male germ cells in vitro., Jessica J. Deane
Immune cell demographics in lipodystrophic adipose tissue., Alison Dempsey
Comparison of 3-D volume measurement by microCT and high frequency ultrasound using the kidney as a model organ., David Len Elion
Hematopoietic and non-hematopoietic effects of CD38 and/or ART2 deficiency in type 1 diabetes., Bethany Evans