Submissions from 2018
Despite high levels of expression in thymic epithelial cells, miR-181a1 and miR-181b1 are not required for thymic development., Heather E Stefanski, Yan Xing, Patricia A Taylor, Stefano Maio, Jorge Henao-Meija, Adam Williams, Richard A Flavell, Georg A Hollander, and Bruce R Blazar
Assessing Healthspan and Lifespan Measures in Aging Mice: Optimization of Testing Protocols, Replicability, and Rater Reliability., Stacey J Sukoff Rizzo, Laura C. Anderson, Torrian L Green, Tracy C. McGarr, Gaylynn Wells, and Shawn S Winter
Skin and adnexa., John P Sundberg, Carmen J. Booth, Lillian B. Nanney, Philip Fleckman, and Lloyd E. King Jr
Training mouse pathologists: 16th annual workshop on the pathology of mouse models of human disease., John P Sundberg, Kelli Boyd, Harm Hogenesch, Alexander Yu Nikitin, Piper M Treuting, and Jerrold M Ward
Cicatricial Alopecia Research Foundation meeting, May 2016: Progress towards the diagnosis, treatment and cure of primary cicatricial alopecias., John P Sundberg, Maria K Hordinsky, Wilma Bergfeld, Yolanda M Lenzy, Amy J McMichael, Angela M Christiano, Tracy McGregor, Kurt S Stenn, Raja K Sivamani, C Herbert Pratt, and Lloyd E King
Living inside the box: environmental effects on mouse models of human disease., John P Sundberg and Paul N Schofield
Sebaceous gland abnormalities in fatty acyl CoA reductase 2 (Far2) null mice result in primary cicatricial alopecia., John P Sundberg, Tong Shen, Oliver Fiehn, Robert H Rice, Kathleen A Silva, Victoria E. Kennedy, Nicholas E Gott, Louise A. Dionne, Lesley S Bechtold, Stephen A. Murray, Raoul Kuiper, and C Herbert Pratt
Concussion, microvascular injury, and early tauopathy in young athletes after impact head injury and an impact concussion mouse model., Chad A Tagge, Andrew M Fisher, Olga V Minaeva, Amanda Gaudreau-Balderrama, Juliet A Moncaster, Xiao-Lei Zhang, Mark W Wojnarowicz, Noel Casey, Haiyan Lu, Olga N Kokiko-Cochran, Sudad Saman, Maria Ericsson, Kristen D. Onos, Ronel Veksler, Vladimir V Senatorov, Asami Kondo, Xiao Z Zhou, Omid Miry, Linnea R Vose, Katisha R Gopaul, Chirag Upreti, Christopher J Nowinski, Robert C Cantu, Victor E Alvarez, Audrey M Hildebrandt, Erich S Franz, Janusz Konrad, James A Hamilton, Ning Hua, Yorghos Tripodis, Andrew T Anderson, Gareth R Howell, Daniela Kaufer, Garth F Hall, Kun P Lu, Richard M Ransohoff, Robin O Cleveland, Neil W Kowall, Thor D Stein, Bruce T Lamb, Bertrand R Huber, William C Moss, Alon Friedman, Patric K Stanton, Ann C McKee, and Lee E Goldstein
Novel therapeutic strategy for cervical cancer harboring FGFR3-TACC3 fusions., Ryo Tamura, Kosuke Yoshihara, Tetsuya Saito, Ryosuke Ishimura, Juan Emmanuel Martínez-Ledesma, Hu Xin, Tatsuya Ishiguro, Yutaro Mori, Kaoru Yamawaki, Kazuaki Suda, Seiya Sato, Hiroaki Itamochi, Teiichi Motoyama, Yoichi Aoki, Shujiro Okuda, Cristine R Casingal, Hirofumi Nakaoka, Ituro Inoue, Roel G W Verhaak, Masaaki Komatsu, and Takayuki Enomoto
3D Axon Growth by Exogenous Electrical Stimulus and Soluble Factors., Min D Tang-Schomer
Cortical Network Synchrony Under Applied Electrical Field, Min D Tang-Schomer, Taylor Jackvony, and Sabato Santaniello
In vitro 3D regeneration-like growth of human patient brain tissue., Min D Tang-Schomer, W B Wu, D L Kaplan, and M J Bookland
A spontaneous mouse deletion in Mctp1 uncovers a long-range cis-regulatory region crucial for NR2F1 function during inner ear development., Basile Tarchini, Chantal M. Longo-Guess, Cong Tian, Abigail L.D. Tadenev, Nicholas Devanney, and Kenneth R. Johnson
Tuning of human MAIT cell activation by commensal bacteria species and MR1-dependent T-cell presentation., Cihan Tastan, Ece Karhan, Wei Zhou, Elizabeth Fleming, Anita Y Voigt, Xudong Yao, Lei Wang, Meghan Horne, Lindsey Placek, Lina Kozhaya, Julia Oh, and Derya Unutmaz
An Integrated Platform for Genome-wide Mapping of Chromatin States Using High-throughput ChIP-sequencing in Tumor Tissues., Christopher Terranova, Ming Tang, Elias Orouji, Mayinuer Maitituoheti, Ayush Raman, Samirkumar B Amin, Zhiyi Liu, and Kunal Rai
A neural network based model effectively predicts enhancers from clinical ATAC-seq samples., Asa Thibodeau, Asli Uyar, Shubham Khetan, Michael L. Stitzel, and Duygu Ucar
A multi-tissue full lifespan epigenetic clock for mice., Michael J Thompson, Karolina Chwiałkowska, Liudmilla Rubbi, Aldons J Lusis, Richard C Davis, Anuj Srivastava, Ron Korstanje, Gary A Churchill, Steve Horvath, and Matteo Pellegrini
CXXC1 is not essential for normal DNA double-strand break formation and meiotic recombination in mouse., Hui Tian, Timothy Billings, and Petko M. Petkov
A robust Pax7EGFP mouse that enables the visualization of dynamic behaviors of muscle stem cells., Elisia D Tichy, David K Sidibe, Christopher D Greer, Nicholas M Oyster, Panteleimon Rompolas, Nadia Rosenthal, Helen M Blau, and Foteini Mourkioti
Comparing phenotypic variation between inbred and outbred mice., Alexander H Tuttle, Vivek M. Philip, Elissa J Chesler, and Jeffrey S Mogil
Alternative-splicing defects in cancer: Splicing regulators and their downstream targets, guiding the way to novel cancer therapeutics., Laura M Urbanski, Nathan Leclair, and Olga Anczuków
Proteomics and metabolomics for analysis of the dynamics of microbiota., Alex Van Belkum, David Broadwell, Douglas Lovern, Lauren M Petersen, George M. Weinstock, and W Michael Dunne
Plain-language medical vocabulary for precision diagnosis., Nicole A Vasilevsky, Erin D Foster, Mark E Engelstad, Leigh Carmody, Matt Might, Chip Chambers, Hugh J S Dawkins, Janine Lewis, Maria G Della Rocca, Michelle Snyder, Cornelius F Boerkoel, Ana Rath, Sharon F Terry, Alastair Kent, Beverly Searle, Gareth Baynam, Erik Jones, Pam Gavin, Michael Bamshad, Jessica Chong, Tudor Groza, David Adams, Adam C Resnick, Allison P Heath, Chris Mungall, Ingrid A Holm, Kayli Rageth, Catherine A Brownstein, Kent Shefchek, Julie A McMurry, Peter N Robinson, Sebastian Köhler, and Melissa A Haendel
Deletion of GARP on mouse regulatory T cells is not sufficient to inhibit the growth of transplanted tumors., E Vermeersch, S Liénart, A Collignon, S Lucas, A Gallimore, C Gysemans, Derya Unutmaz, K Vanhoorelbeke, S F De Meyer, W Maes, and H Deckmyn
The Energetics and Physiological Impact of Cohesin Extrusion., Laura Vian, Aleksandra Pękowska, Suhas S P Rao, Kyong-Rim Kieffer-Kwon, Seolkyoung Jung, Laura Baranello, Su-Chen Huang, Laila El Khattabi, Marei Dose, Nathanael Pruett, Adrian L Sanborn, Andres Canela, Yaakov Maman, Anna Oksanen, Wolfgang Resch, Xingwang Li, Byoungkoo Lee, Alexander L Kovalchuk, Zhonghui Tang, Steevenson Nelson, Michele Di Pierro, Ryan R Cheng, Ido Machol, Brian Glenn St Hilaire, Neva C Durand, Muhammad S Shamim, Elena K Stamenova, José N Onuchic, Yijun Ruan, Andre Nussenzweig, David Levens, Erez Lieberman Aiden, and Rafael Casellas
Research Directions in the Clinical Implementation of Pharmacogenomics: An Overview of US Programs and Projects., Simona Volpi, Carol J Bult, Rex L Chisholm, Patricia A Deverka, Geoffrey S Ginsburg, Howard J Jacob, Melpomeni Kasapi, Howard L McLeod, Dan M Roden, Marc S Williams, Eric D Green, Laura Lyman Rodriguez, Samuel Aronson, Larisa H Cavallari, Joshua C Denny, Lynn G Dressler, Julie A Johnson, Teri E Klein, J Steven Leeder, Micheline Piquette-Miller, Minoli Perera, Laura J Rasmussen-Torvik, Heidi L Rehm, Marylyn D Ritchie, Todd C Skaar, Nikhil Wagle, Richard Weinshilboum, Kristin W Weitzel, Robert Wildin, John Wilson, Teri A Manolio, and Mary V Relling
ANKRD16 prevents neuron loss caused by an editing-defective tRNA synthetase., My-Nuong Vo, Markus Terrey, Jeong Woong Lee, Bappaditya Roy, James J Moresco, Litao Sun, Hongjun Fu, Qi Liu, Thomas G Weber, John R Yates, Kurt Fredrick, Paul Schimmel, and Susan L Ackerman
Alström syndrome: Renal findings in correlation with obesity, insulin resistance, dyslipidemia and cardiomyopathy in 38 patients prospectively evaluated at the NIH clinical center., Meryl Waldman, Joan C Han, Daniela P Reyes-Capo, Joy Bryant, Kathryn A Carson, Baris Turkbey, Peter Choyke, Juergen K. Naggert, William A Gahl, Jan D Marshall, and Meral Gunay-Aygun
COX-2/sEH Dual Inhibitor PTUPB Potentiates the Antitumor Efficacy of Cisplatin., Fuli Wang, Hongyong Zhang, Ai-Hong Ma, Weimin Yu, Maike Zimmermann, Jun Yang, Sung Hee Hwang, Daniel Zhu, Tzu-Yin Lin, Michael Malfatti, Kenneth W Turteltaub, Paul T Henderson, Susan Airhart, Bruce D Hammock, Jianlin Yuan, Ralph W de Vere White, and Chong-Xian Pan
Deletion of Nrip1 Extends Female Mice Longevity, Increases Autophagy, and Delays Cell Senescence., Jinyu Wang, Xundi Chen, Jared Osland, Skyler J Gerber, Chao Luan, Kristin Delfino, Leslie Goodwin, and Rong Yuan
Humanized mice in studying efficacy and mechanisms of PD-1-targeted cancer immunotherapy., Minan Wang, Li-Chin Yao, Mingshan Cheng, Danying Cai, Jan Martinek, Chong-Xian Pan, Wei Shi, Ai-Hong Ma, Ralph W De Vere White, Susan Airhart, Edison T Liu, Jacques Banchereau, Michael A Brehm, Dale L Greiner, Leonard D. Shultz, Karolina Palucka, and James G. Keck
Whole-exome sequencing capture kit biases yield false negative mutation calls in TCGA cohorts., Victor G Wang, Hyunsoo Kim, and Jeffrey Chuang
A Bayesian Framework for Generalized Linear Mixed Modeling Identifies New Candidate Loci for Late-Onset Alzheimer's Disease., Xulong Wang, Vivek M. Philip, Guruprasad Ananda, Charles C White, Ankit Malhotra, Paul J Michalski, Krishna R Murthy Karuturi, Sumana R Chintalapudi, Casey Acklin, Michael Sasner, David A Bennett, Philip L De Jager, Gareth R Howell, and Gregory W. Carter
Meta-analysis of human gene expression in response to Mycobacterium tuberculosis infection reveals potential therapeutic targets., Zhang Wang, Seda Arat, Michal Magid-Slav, and James R Brown
Biological explanations for discordant noninvasive prenatal test results: Preliminary data and lessons learned., Louise Wilkins-Haug, Chengsheng Zhang, Eliza Cerveira, Mallory Ryan, Adam Mil-Homens, Qihui Zhu, Honey V Reddi, Charles Lee, and Diana W Bianchi
Nicotinamide treatment robustly protects from inherited mouse glaucoma., Pete A. Williams, Jeffrey M. Harder, Brynn H Cardozo, Nicole E Foxworth, and Simon W M John
Preclinical assessment of antiviral combination therapy in a genetically humanized mouse model for hepatitis delta virus infection., Benjamin Y Winer, Elham Shirvani-Dastgerdi, Yaron Bram, Julie Sellau, Benjamin E. Low, Heath Johnson, Tiffany Huang, Gabriela Hrebikova, Brigitte Heller, Yael Sharon, Katja Giersch, Sherif Gerges, Kathleen Seneca, Mihai-Alexandru Pais, Angela S Frankel, Luis Chiriboga, John Cullen, Ronald G Nahass, Marc Lutgehetmann, Jared E Toettcher, Michael V. Wiles, Robert E Schwartz, and Alexander Ploss
Homeward bound: The capacity of the food hoarding task to assess complex cognitive processes., Shawn S Winter, Philip A Blankenship, and Max L Mehlman
Injectable polypeptide hydrogels via methionine modification for neural stem cell delivery., A L Wollenberg, T M O'Shea, J H Kim, Anne M Czechanski, Laura G Reinholdt, M V Sofroniew, and T J Deming
IL1 Receptor Antagonist Controls Transcriptional Signature of Inflammation in Patients with Metastatic Breast Cancer., Te-Chia Wu, Kangling Xu, Jan Martinek, Robyn R Young, Romain Banchereau, Joshy George, Jacob Turner, Kyung In Kim, Sandra Zurawski, Xuan Wang, Derek Blankenship, Hannah M Brookes, Florentina Marches, Gerlinde Obermoser, Elizabeth Lavecchio, Maren K Levin, Sookyoung Bae, Cheng-Han Chung, Jennifer L Smith, Alma-Martina Cepika, Kyp L Oxley, George J Snipes, Jacques Banchereau, Virginia Pascual, Joyce O'Shaughnessy, and A. Karolina Palucka
Two-phase differential expression analysis for single cell RNA-seq., Zhijin Wu, Yi Zhang, Michael L. Stitzel, and Hao Wu
The Genetic Landscape of Hypoplastic Left Heart Syndrome., Hisato Yagi, Xiaoqin Liu, George C Gabriel, Yijen Wu, Kevin A Peterson, Stephen A. Murray, Bruce J Aronow, Lisa J Martin, D Woodrow Benson, and Cecilia W Lo
Restoration of vision after de novo genesis of rod photoreceptors in mammalian retinas., Kai Yao, Suo Qiu, Yanbin V Wang, Silvia J H Park, Ethan J Mohns, Bhupesh Mehta, Xinran Liu, Bo Chang, David Zenisek, Michael C Crair, Jonathan B Demb, and Bo Chen
Modularity of the metabolic gene network as a prognostic biomarker for hepatocellular carcinoma., Fengdan Ye, Dongya Jia, Mingyang Lu, Herbert Levine, and Michael W Deem
A pan-cancer analysis of driver gene mutations, DNA methylation and gene expressions reveals that chromatin remodeling is a major mechanism inducing global changes in cancer epigenomes., Ahrim Youn, Kyung In Kim, Raul Rabadan, Benjamin Tycko, Yufeng Shen, and Shuang Wang
Genome-wide association for testis weight in the diversity outbred mouse population., Joshua T Yuan, Daniel M. Gatti, Vivek M. Philip, Steven Kasparek, Andrew M Kreuzman, Benjamin Mansky, Kayvon Sharif, Dominik Taterra, Walter M Taylor, Mary Thomas, Jeremy O Ward, Andrew Holmes, Elissa J Chesler, and Clarissa C Parker
Humanizing the mdx mouse model of DMD: the long and the short of it., Nora Yucel, Alex C Chang, John W Day, Nadia Rosenthal, and Helen M Blau
Multicolor Fluorescence In Situ Hybridization (FISH) Approaches for Simultaneous Analysis of the Entire Human Genome., Chengsheng Zhang, Eliza Cerveira, Willem Rens, Fengtang Yang, and Charles Lee
Joint principal trend analysis for longitudinal high-dimensional data., Yuping Zhang and Zhengqing Ouyang
Primary hepatic neuroendocrine carcinoma: report of two cases and literature review., Zi-Ming Zhao, Jin Wang, Ugochukwu C Ugwuowo, Liming Wang, and Jeffrey P Townsend
Thanatomicrobiome composition profiling as a tool for forensic investigation., Wei Zhou and Yingnan Bian
ReprDB and panDB: minimalist databases with maximal microbial representation., Wei Zhou, Nicole R Gay, and Julia Oh
Systematic analysis of copy number variation associated with congenital diaphragmatic hernia., Qihui Zhu, Frances A High, Chengsheng Zhang, Eliza Cerveira, Meaghan K Russell, Mauro Longoni, Maliackal P Joy, Mallory Ryan, Adam Mil-Homens, Lauren Bellfy, Caroline M Coletti, Pooja Bhayani, Regis Hila, Jay M Wilson, Patricia K Donahoe, and Charles Lee