Submissions from 2017
Combination of IL-10 and IL-2 induces oligoclonal human CD4 T cell expansion during xenogeneic and allogeneic GVHD in humanized mice., Sojan Abraham, Hua Guo, Jang-Gi Choi, Chunting Ye, Midhun Ben Thomas, Nora Ortega, Alok Dwivedi, N Manjunath, Guohua Yi, and Premlata Shankar
Age exacerbates abnormal protein expression in a mouse model of Down syndrome., Md Mahiuddin Ahmed, Aaron Block, Suhong Tong, Muriel T. Davisson, and Katheleen J Gardiner
I-ATAC: interactive pipeline for the management and pre-processing of ATAC-seq samples., Zeeshan Ahmed and Duygu Ucar
Navigating the Cancer Transcriptome by Decoding Divergent Oncogenic States., Samirkumar B Amin and Roel G W Verhaak
Assessing the Safety of Human Pluripotent Stem Cells and Their Derivatives for Clinical Applications., Peter W Andrews, Uri Ben-David, Nissim Benvenisty, Peter Coffey, Kevin Eggan, Barbara B. Knowles, Andras Nagy, Martin Pera, Benjamin Reubinoff, Peter J Rugg-Gunn, and Glyn N Stacey
Optimization and Control of Agent-Based Models in Biology: A Perspective., G An, B G Fitzpatrick, S Christley, P Federico, A Kanarek, R Miller Neilan, M Oremland, R Salinas, Reinhard Laubenbacher, and S Lenhart
Molecular features of influenza A (H1N1)pdm09 prevalent in Mexico during winter seasons 2012-2014., Rocío Arellano-Llamas, Luis Alfaro-Ruiz, Cristian Arriaga Canon, Ivan Imaz Rosshandler, Alfredo Cruz-Lagunas, Joaquín Zúñiga, Rosa Rebollar Vega, Christopher W Wong, Sebastian Maurer-Stroh, Sandra Romero Córdoba, Edison T Liu, Alfredo Hidalgo-Miranda, and Joel A Vázquez-Pérez
A Prospective Cohort Multicenter Study of Molecular Epidemiology and Phylogenomics of Staphylococcus aureus Bacteremia in Nine Latin American Countries., Cesar A Arias, Jinnethe Reyes, Lina Paola Carvajal, Sandra Rincon, Lorena Diaz, Diana Panesso, Gabriel Ibarra, Rafael Rios, Jose M Munita, Mauro J Salles, Carlos Alvarez-Moreno, Jaime Labarca, Coralith Garcia, Carlos M Luna, Carlos Mejia-Villatoro, Jeannete Zurita, Manuel Guzman-Blanco, Eduardo Rodriguez-Noriega, Apurva Narechania, Laura J Rojas, Paul J Planet, George M Weinstock, Eduardo Gotuzzo, and Carlos Seas
Tutorial on Protein Ontology Resources., Cecilia N Arighi, Harold J. Drabkin, Karen R. Christie, Karen E Ross, and Darren A Natale
An atypical role for the myeloid receptor Mincle in central nervous system injury., Thiruma V Arumugam, Silvia Manzanero, Milena B Furtado, Patrick J Biggins, Yu-Hsuan Hsieh, Mathias Gelderblom, Kelli Pa MacDonald, Ekaterina Salimova, Yu-I Li, Othmar Korn, Deborah Dewar, I Mhairi Macrae, Robert B Ashman, Sung-Chun Tang, Nadia Rosenthal, Marc J Ruitenberg, Tim Magnus, and Christine A Wells
Influenza vaccines differentially regulate the interferon response in human dendritic cell subsets., Shruti Athale, Romain Banchereau, LuAnn Thompson-Snipes, Yuanyuan Wang, Karolina Palucka, Virginia Pascual, and Jacques Banchereau
How mice are indispensable for understanding obesity and diabetes genetics., Alan D Attie, Gary A Churchill, and Joseph H Nadeau
Mean vector testing for high-dimensional dependent observations., Deepak Nag Ayyala, Junyong Park, and Anindya Roy
Regenerative medicine: are we there yet?, Stephen Badylak and Nadia Rosenthal
CloudNeo: A cloud pipeline for identifying patient-specific tumor neoantigens., Preeti Bais, Sandeep Namburi, Daniel M. Gatti, Xinyu Zhang, and Jeffrey Chuang
Understanding Human Autoimmunity and Autoinflammation Through Transcriptomics., Romain Banchereau, Alma-Martina Cepika, Jacques Banchereau, and Virginia Pascual
Systematic analysis of telomere length and somatic alterations in 31 cancer types., Floris P Barthel, Wei Wei, Ming Tang, Emmanuel Martinez-Ledesma, Xin Hu, Samirkumar B Amin, Kadir C Akdemir, Sahil Seth, Xingzhi Song, Qianghu Wang, Tara Lichtenberg, Jian Hu, Jianhua Zhang, Siyuan Zheng, and Roel G W Verhaak
Impact of Age, Caloric Restriction, and Influenza Infection on Mouse Gut Microbiome: An Exploratory Study of the Role of Age-Related Microbiome Changes on Influenza Responses., Jenna M Bartley, Xin Zhou, George A Kuchel, George M. Weinstock, and Laura Haynes
Iron addiction: a novel therapeutic target in ovarian cancer., D Basuli, L Tesfay, Z Deng, B Paul, Y Yamamoto, Gang Ning, W Xian, F McKeon, M Lynch, C P Crum, P Hegde, M Brewer, X Wang, L D Miller, N Dyment, F M Torti, and S V Torti
Preclinical testing of the glycogen synthase kinase-3β inhibitor tideglusib for rhabdomyosarcoma., Narendra Bharathy, Matthew N Svalina, Teagan P Settelmeyer, Megan M Cleary, Noah E Berlow, Susan D Airhart, Sunny Xiang, James Keck, James B Hayden, Jack F Shern, Atiya Mansoor, Melvin Lathara, Ganapati Srinivasa, David M Langenau, and Charles Keller
Mouse Genome Database (MGD)-2017: community knowledge resource for the laboratory mouse., Judith A. Blake, Janan T. Eppig, James A. Kadin, Joel E Richardson, Cynthia Smith, Carol J Bult, and Mouse Genome Database Group
Multicenter Systems Analysis of Human Blood Reveals Immature Neutrophils in Males and During Pregnancy., Jana Blazkova, Sarthak Gupta, Yudong Liu, Brice Gaudilliere, Edward A Ganio, Christopher R Bolen, Ron Saar-Dover, Gabriela K Fragiadakis, Martin S Angst, Sarfaraz Hasni, Nima Aghaeepour, David Stevenson, Nicole Baldwin, Esperanza Anguiano, Damien Chaussabel, Matthew C Altman, Mariana J Kaplan, Mark M Davis, and David Furman
Respiratory manifestations in 38 patients with Alström syndrome., Caroline Boerwinkle, Jan D Marshall, Joy Bryant, William A Gahl, Kenneth N Olivier, and Meral Gunay-Aygun
Review of CO₂ as a Euthanasia Agent for Laboratory Rats and Mice., Gregory P Boivin, Debra L Hickman, Michelle A Creamer-Hente, Kathleen R Pritchett-Corning, and Natalie A Bratcher
Survival Advantage of Both Human Hepatocyte Xenografts and Genome-Edited Hepatocytes for Treatment of α-1 Antitrypsin Deficiency., Florie Borel, Qiushi Tang, Gwladys Gernoux, Cynthia Greer, Ziqiong Wang, Adi Barzel, Mark A Kay, Leonard D. Shultz, Dale L Greiner, Terence R Flotte, Michael A Brehm, and Christian Mueller
Minimum information about a single amplified genome (MISAG) and a metagenome-assembled genome (MIMAG) of bacteria and archaea., Robert M Bowers, Nikos C Kyrpides, Ramunas Stepanauskas, Miranda Harmon-Smith, Devin Doud, T B K Reddy, Frederik Schulz, Jessica Jarett, Adam R Rivers, Emiley A Eloe-Fadrosh, Susannah G Tringe, Natalia N Ivanova, Alex Copeland, Alicia Clum, Eric D Becraft, Rex R Malmstrom, Bruce Birren, Mircea Podar, Peer Bork, George M. Weinstock, George M Garrity, Jeremy A Dodsworth, Shibu Yooseph, Granger Sutton, Frank O Glöckner, Jack A Gilbert, William C Nelson, Steven J Hallam, Sean P Jungbluth, Thijs J G Ettema, Scott Tighe, Konstantinos T Konstantinidis, Wen-Tso Liu, Brett J Baker, Thomas Rattei, Jonathan A Eisen, Brian Hedlund, Katherine D McMahon, Noah Fierer, Rob Knight, Rob Finn, Guy Cochrane, Ilene Karsch-Mizrachi, Gene W Tyson, Christian Rinke, Alla Lapidus, Folker Meyer, Pelin Yilmaz, Donovan H Parks, A M Eren, Lynn Schriml, Jillian F Banfield, Philip Hugenholtz, and Tanja Woyke
A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction., Michael R Bowl, Michelle M Simon, Neil J Ingham, Simon Greenaway, Luis Santos, Heather Cater, Sarah Taylor, Jeremy Mason, Natalja Kurbatova, Selina Pearson, Lynette R Bower, Dave A Clary, Hamid Meziane, Patrick Reilly, Osamu Minowa, Lois Kelsey, International Mouse Phenotyping Consortium, Glauco P Tocchini-Valentini, Xiang Gao, Allan Bradley, William C Skarnes, Mark Moore, Arthur L Beaudet, Monica J Justice, John Seavitt, Mary E Dickinson, Wolfgang Wurst, Martin Hrabe de Angelis, Yann Herault, Shigeharu Wakana, Lauryl M J Nutter, Ann M Flenniken, Colin McKerlie, Stephen A. Murray, Karen L. Svenson, Robert E Braun, David B West, K C Kent Lloyd, David J Adams, Jacqui White, Natasha Karp, Paul Flicek, Damian Smedley, Terrence F Meehan, Helen E Parkinson, Lydia M Teboul, Sara Wells, Karen P Steel, Ann-Marie Mallon, and Steve D M Brown
GlioVis data portal for visualization and analysis of brain tumor expression datasets., Robert L Bowman, Qianghu Wang, Angel Carro, Roel G W Verhaak, and Massimo Squatrito
International Cooperation to Enable the Diagnosis of All Rare Genetic Diseases., Kym M Boycott, Ana Rath, Jessica X Chong, Taila Hartley, Fowzan S Alkuraya, Gareth Baynam, Anthony J Brookes, Michael Brudno, Angel Carracedo, Johan T den Dunnen, Stephanie O M Dyke, Xavier Estivill, Jack Goldblatt, Catherine Gonthier, Stephen C Groft, Ivo Gut, Ada Hamosh, Philip Hieter, Sophie Höhn, Matthew E Hurles, Petra Kaufmann, Bartha M Knoppers, Jeffrey P Krischer, Milan Macek, Gert Matthijs, Annie Olry, Samantha Parker, Justin Paschall, Anthony A Philippakis, Heidi L Rehm, Peter N Robinson, Pak-Chung Sham, Rumen Stefanov, Domenica Taruscio, Divya Unni, Megan R Vanstone, Feng Zhang, Han Brunner, Michael J Bamshad, and Hanns Lochmüller
Characteristics of cardiomyopathy in Alström syndrome: Prospective single-center data on 38 patients., Alessandra Brofferio, Vandana Sachdev, Hwaida Hannoush, Jan D. Marshall, Juergen K. Naggert, Stanislav Sidenko, Anna Noreuil, Arlene Sirajuddin, Joy Bryant, Joan C Han, Andrew E Arai, William A Gahl, and Meral Gunay-Aygun
A Gene Implicated in Activation of Retinoic Acid Receptor Targets Is a Novel Renal Agenesis Gene in Humans., Patrick D Brophy, Maria Rasmussen, Mrutyunjaya Parida, Greg Bonde, Benjamin W Darbro, Xiaojing Hong, Jason C Clarke, Kevin A Peterson, James Denegre, Michael Schneider, Caroline R Sussman, Lone Sunde, Dorte L Lildballe, Jens Michael Hertz, Robert A Cornell, Stephen A. Murray, and J Robert Manak
Effects of research complexity and competition on the incidence and growth of coauthorship in biomedicine., Jason Cory Brunson, Xiaoyan Wang, and Reinhard Laubenbacher
Integrative Functional Genomics for Systems Genetics in GeneWeaver.org., Jason A. Bubier, Michael A Langston, Erich J Baker, and Elissa J Chesler
Confined placental mosaicism for 22q11.2 deletion as the etiology for discordant positive NIPT results., M Bunnell, Chengsheng Zhang, Charles Lee, D W Bianchi, and L Wilkins-Haug
Patient-derived xenografts of low-grade B-cell lymphomas demonstrate roles of the tumor microenvironment., W Richard Burack, Janice M Spence, John P Spence, Stephen A Spence, Philip J Rock, Gautam N Shenoy, Leonard D. Shultz, Richard B Bankert, and Steven H Bernstein
Abnormalities in the Structure and Function of Cerebellar Neurons and Neuroglia in the Lc/+ Chimeric Mouse Model of Variable Developmental Purkinje Cell Loss., James Cairns, Doug Swanson, Joanna Yeung, Anna Sinova, Ronny Chan, Praneetha Potluri, Price E. Dickson, Guy Mittleman, and Dan Goldowitz
Adolescent Obesity and Insulin Resistance: Roles of Ectopic Fat Accumulation and Adipose Inflammation., Sonia Caprio, Rachel Perry, and Romy Kursawe
Assessing the potential for raw meat to influence human colonization with Staphylococcus aureus., Margaret Carrel, Chang Zhao, Dipendra Thapaliya, Patrick Bitterman, Ashley E Kates, Blake M Hanson, and Tara C Smith
A multidimensional blood stimulation assay reveals immune alterations underlying systemic juvenile idiopathic arthritis., Alma-Martina Cepika, Romain Banchereau, Elodie Segura, Marina Ohouo, Brandi Cantarel, Kristina Goller, Victoria Cantrell, Emily Ruchaud, Elizabeth Gatewood, Phuong Nguyen, Jinghua Gu, Esperanza Anguiano, Sandra Zurawski, Jeanine M Baisch, Marilynn Punaro, Nicole Baldwin, Gerlinde Obermoser, Karolina Palucka, Jacques Banchereau, Sebastian Amigorena, and Virginia Pascual
A mutagenesis-derived Lrp5 mouse mutant with abnormal retinal vasculature and low bone mineral density., Jeremy R. Charette, Sarah E Earp, Brent A Bell, Cheryl L Ackert-Bicknell, Dana A Godfrey, Sujata Rao, Bela Anand-Apte, Patsy M. Nishina, and Neal S Peachey
Activated Oncogenic Pathway Modifies Iron Network in Breast Epithelial Cells: A Dynamic Modeling Perspective., Julia Chifman, Seda Arat, Zhiyong Deng, Erica Lemler, James C Pino, Leonard A Harris, Michael A Kochen, Carlos F Lopez, Steven A Akman, Frank M Torti, Suzy V Torti, and Reinhard Laubenbacher
A Novel Combination Treatment Targeting BCL-XL and MCL1 for KRAS/BRAF-mutated and BCL2L1-amplified Colorectal Cancers., Sung-Yup Cho, Jee Yun Han, Deukchae Na, Wonyoung Kang, Ahra Lee, Jooyoung Kim, Jieun Lee, Seoyeon Min, Jinjoo Kang, Jeesoo Chae, Jong-Il Kim, Hansoo Park, Won-Suk Lee, and Charles Lee
High prevalence of TP53 mutations is associated with poor survival and an EMT signature in gliosarcoma patients., Sung-Yup Cho, Changho Park, Deukchae Na, Jee Yun Han, Jieun Lee, Ok-Kyoung Park, Chengsheng Zhang, Chang Ohk Sung, Hyo Eun Moon, Yona Kim, Jeong Hoon Kim, Jong Jae Kim, Shin Kwang Khang, Do-Hyun Nam, Jung Won Choi, Yeon-Lim Suh, Dong Gyu Kim, Sung Hye Park, Hyewon Youn, Kyuson Yun, Jong-Il Kim, Charles Lee, Sun Ha Paek, and Hansoo Park
Small-world networks exhibit pronounced intermittent synchronization., Anshul Choudhary, Chiranjit Mitra, Vivek Kohar, Sudeshna Sinha, and Jürgen Kurths
S100A4 Is a Biomarker and Regulator of Glioma Stem Cells That Is Critical for Mesenchymal Transition in Glioblastoma., Kin-Hoe Chow, Hee Jung Park, Joshy George, Keiko Yamamoto, Andrew D Gallup, Joel H. Graber, Yuanxin Chen, Wen Jiang, Dennis A Steindler, Eric G Neilson, Betty Y S Kim, and Kyuson Yun
The rs7903146 Variant in the TCF7L2 Gene Increases the Risk of Prediabetes/Type 2 Diabetes in Obese Adolescents by Impairing β-Cell Function and Hepatic Insulin Sensitivity., Catrina Cropano, Nicola Santoro, Leif Groop, Chiara Dalla Man, Claudio Cobelli, Alfonso Galderisi, Romy Kursawe, Bridget Pierpont, Martina Goffredo, and Sonia Caprio
Age-dependent human β cell proliferation induced by glucagon-like peptide 1 and calcineurin signaling., Chunhua Dai, Yan Hang, Alena Shostak, Greg Poffenberger, Nathaniel Hart, Nripesh Prasad, Neil Phillips, Shawn E Levy, Dale L Greiner, Leonard D. Shultz, Rita Bottino, Seung K Kim, and Alvin C Powers
Lithium reduces blood glucose levels, but aggravates albuminuria in BTBR-ob/ob mice., Theun de Groot, Lars Damen, Leanne Kosse, Mohammad Alsady, Rosalinda A. Doty, Ruben Baumgarten, Susan Sheehan, Johan van der Vlag, Ron Korstanje, and Peter M T Deen
Editorial overview: Characterizing the cancer genome: mechanistic insights and translational opportunities., Olivier Delattre and Carol J Bult
QTL and systems genetics analysis of mouse grooming and behavioral responses to novelty in an open field., A Delprato, M-P Algéo, B Bonheur, Jason A. Bubier, L Lu, R W Williams, Elissa J Chesler, and W E Crusio
Neutralizing Antibody Responses to Viral Infections Are Linked to the Non-classical MHC Class II Gene H2-Ob., Lisa K Denzin, Aly A Khan, Francesca Virdis, Jessica Wilks, Melissa Kane, Helen A Beilinson, Stanislav Dikiy, Laure K Case, Derry C. Roopenian, Michele Witkowski, Alexander V Chervonsky, and Tatyana V Golovkina
Cerebellar contribution to higher and lower order rule learning and cognitive flexibility in mice., Price E. Dickson, J Cairns, D Goldowitz, and G Mittleman
Spectral-domain optical coherence tomography findings in Alström syndrome., Gad Dotan, Vikas Khetan, Jan D Marshall, Elizabeth Affel, Denise Armiger-George, Juergen K. Naggert, Gayle B. Collin, and Alex V Levin
Interferon-γ Limits Diabetogenic CD8(+) T-Cell Effector Responses in Type 1 Diabetes., John P Driver, Jeremy Racine, Cheng Ye, Deanna J Lamont, Brittney N Newby, Caroline M. Leeth, Harold D. Chapman, Todd M Brusko, Yi-Guang Chen, Clayton E Mathews, and David V. Serreze
Expression and function of ABCG2 and XIAP in glioblastomas., Ivette F Emery, Archana Gopalan, Stephanie Wood, Kin-Hoe Chow, Chiara Battelli, Joshy George, Hagen Blaszyk, Jeffrey Florman, and Kyuson Yun
Mouse Genome Informatics (MGI) Resource: Genetic, Genomic, and Biological Knowledgebase for the Laboratory Mouse., Janan T. Eppig
Mouse Genome Informatics (MGI): Resources for Mining Mouse Genetic, Genomic, and Biological Data in Support of Primary and Translational Research., Janan T. Eppig, Cynthia Smith, Judith A. Blake, Martin Ringwald, James A. Kadin, Joel E Richardson, and Carol J Bult
EIF1AX and NRAS Mutations Co-occur and Cooperate in Low-Grade Serous Ovarian Carcinomas., Dariush Etemadmoghadam, Walid J Azar, Ying Lei, Tania Moujaber, Dale W Garsed, Catherine J Kennedy, Sian Fereday, Chris Mitchell, Yoke-Eng Chiew, Joy Hendley, Raghwa Sharma, Paul R Harnett, Jason Li, Elizabeth L Christie, Ann-Marie Patch, Joshy George, George Au-Yeung, Gisela Mir Arnau, Timothy P Holloway, Timothy Semple, John V Pearson, Nicola Waddell, Sean M Grimmond, Martin Köbel, Helen Rizos, Ivan B Lomakin, David D L Bowtell, and Anna deFazio
Antibiotic-associated Manipulation of the Gut Microbiota and Phenotypic Restoration in NOD Mice., James R Fahey, Bonnie L. Lyons, Haiyan L Olekszak, Anthony J Mourino, Jeremy Ratiu, Jeremy Racine, Harold D Chapman, David V. Serreze, Dina L Baker, and N Ken Hendrix
Novel Endomorphin Analogs Are More Potent and Longer-Lasting Analgesics in Neuropathic, Inflammatory, Postoperative, and Visceral Pain Relative to Morphine., Amy K Feehan, Jenny Morgenweck, Xing Zhang, Ariel T Amgott-Kwan, and James E Zadina
The mouse Gene Expression Database (GXD): 2017 update., Jacqueline H. Finger, Constance M. Smith, Terry F. Hayamizu, Ingeborg J. McCright, Jingxia Xu, MeiYee Law, David R. Shaw, Richard M. Baldarelli, Jon S Beal, Olin Blodgett, Jeff W Campbell, Lori E. Corbani, Jill R Lewis, Kim L. Forthofer, Pete J. Frost, Sharon C Giannatto, Lucie Hutchins, Dave Miers, Howie Motenko, Kevin R. Stone, Janan T. Eppig, James A. Kadin, Joel E Richardson, and Martin Ringwald
Sequence data and association statistics from 12,940 type 2 diabetes cases and controls., Jason Flannick, Michael L. Stitzel, and et al
HIV-Infected Children Have Elevated Levels of PD-1+ Memory CD4 T Cells With Low Proliferative Capacity and High Inflammatory Cytokine Effector Functions., Julia Foldi, Lina Kozhaya, Bret McCarty, Mussa Mwamzuka, Fatma Marshed, Tiina Ilmet, Max Kilberg, Adam Kravietz, Aabid Ahmed, William Borkowsky, Derya Unutmaz, and Alka Khaitan
EMT/MET at the Crossroad of Stemness, Regeneration and Oncogenesis: The Ying-Yang Equilibrium Recapitulated in Cell Spheroids., Elvira Forte, Isotta Chimenti, Paolo Rosa, Francesco Angelini, Francesca Pagano, Antonella Calogero, Alessandro Giacomello, and Elisa Messina
Properties and Immune Function of Cardiac Fibroblasts., Milena B Furtado and Muneer G. Hasham
Mutations in the Katnb1 gene cause left-right asymmetry and heart defects., Milena B Furtado, D Jo Merriner, Silke Berger, Danielle Rhodes, Duangporn Jamsai, and Moira K O'Bryan
Point mutations in murine Nkx2-5 phenocopy human congenital heart disease and induce pathogenic Wnt signaling., Milena B Furtado, Julia C Wilmanns, Anjana Chandran, Joelle Perera, Olivia Hon, Christine Biben, Taylor J Willow, Hieu T Nim, Gurpreet Kaur, Stephanie Simonds, Qizhu Wu, David Willians, Ekaterina Salimova, Nicolas Plachta, James M. Denegre, Stephen A. Murray, Diane Fatkin, Michael Cowley, James T Pearson, David Kaye, Mirana Ramialison, Richard P Harvey, Nadia A Rosenthal, and Mauro W Costa
Normal behavioral responses to light and darkness and the pupillary light reflex are dependent upon the olivary pretectal nucleus in the diurnal Nile grass rat., Andrew J Gall, Ohanes S Khacherian, Brandi Ledbetter, Sean P Deats, Megan Luck, Laura Smale, Lily Yan, and Antonio A Nunez
Defining Disease, Diagnosis, and Translational Medicine within a Homeostatic Perturbation Paradigm: The National Institutes of Health Undiagnosed Diseases Program Experience., Timothy Gall, Elise Valkanas, Christofer Bello, Thomas Markello, Christopher Adams, William P Bone, Alexander J Brandt, Jennifer M Brazill, Lynn Carmichael, Mariska Davids, Joie Davis, Zoraida Diaz-Perez, David Draper, Jeremy Elson, Elise D Flynn, Rena Godfrey, Catherine Groden, Cheng-Kang Hsieh, Roxanne Fischer, Gretchen A Golas, Jessica Guzman, Yan Huang, Megan S Kane, Elizabeth Lee, Chong Li, Amanda E Links, Valerie Maduro, May Christine V Malicdan, Fayeza S Malik, Michele Nehrebecky, Joun Park, Paul Pemberton, Katherine Schaffer, Dimitre Simeonov, Murat Sincan, Damian Smedley, Zaheer Valivullah, Colleen Wahl, Nicole Washington, Lynne A Wolfe, Karen Xu, Yi Zhu, William A Gahl, Cynthia J Tifft, Camillo Toro, David R Adams, Miao He, Peter N Robinson, Melissa A Haendel, R Grace Zhai, and Cornelius F Boerkoel
QTL Mapping and Identification of Candidate Genes in DO Mice: A Use Case Model Derived from a Benzene Toxicity Experiment., Daniel Mario Gatti, John E French, and Klaus Schughart
Biometric and structural ocular manifestations of Marfan syndrome., Petra Gehle, Barbara Goergen, Daniel Pilger, Peter Ruokonen, Peter N Robinson, and Daniel J Salchow
Promiscuous DNA-binding of a mutant zinc finger protein corrupts the transcriptome and diminishes cell viability., Kevin R Gillinder, Melissa D Ilsley, Danitza Nébor, Ravi Sachidanandam, Mathieu Lajoie, Graham W Magor, Michael R Tallack, Timothy Bailey, Michael J Landsberg, Joel P Mackay, Michael W Parker, Luke A Miles, Joel H. Graber, Luanne L. Peters, James J Bieker, and Andrew C Perkins
Heart regeneration in the salamander relies on macrophage-mediated control of fibroblast activation and the extracellular landscape., James W Godwin, R Debuque, E Salimova, and Nadia A Rosenthal
Chasing the recipe for a pro-regenerative immune system., James W Godwin, Alexander R Pinto, and Nadia A Rosenthal
Albumin, in the Presence of Calcium, Elicits a Massive Increase in Extracellular Bordetella Adenylate Cyclase Toxin., Laura A Gonyar, Mary C Gray, Gregory J. Christianson, Borna Mehrad, and Erik L Hewlett
Targeting interferon-alpha to dendritic cells enhances a CD8(+) T cell response to a human CD40-targeted cancer vaccine., John P Graham, Pierre Authie, A Karolina Palucka, and Gerard Zurawski
Genome-wide DNA methylation profiling reveals cancer-associated changes within early colonic neoplasia., M P Hanley, M A Hahn, A X Li, X Wu, Jianan Lin, J Wang, A H Choi, Zhengqing Ouyang, Y Fong, G P Pfeifer, T J Devers, and D W Rosenberg
Early immune responses are independent of RGC dysfunction in glaucoma with complement component C3 being protective., Jeffrey M. Harder, Catherine E. Braine, Pete A. Williams, Xianjun Zhu, Katharine H Macnicoll, Gregory L Sousa, Rebecca A Buchanan, Richard S Smith, Richard T Libby, Gareth R Howell, and Simon W M John
Systemic autoimmunity induced by the TLR7/8 agonist Resiquimod causes myocarditis and dilated cardiomyopathy in a new mouse model of autoimmune heart disease., Muneer G. Hasham, Nicoleta Baxan, Daniel J Stuckey, Jane Branca, Bryant Perkins, Oliver Dent, Ted Duffy, Tolani S Hameed, Sarah E Stella, Mohammed Bellahcene, Michael D Schneider, Sian E Harding, Nadia Rosenthal, and Susanne Sattler
Genetic and epigenetic heterogeneity and the impact on cancer relapse., Ciaran Hassan, Ebrahim Afshinnekoo, Sheng Li, Shixiu Wu, and Christopher E Mason
Early induction of NRF2 antioxidant pathway by RHBDF2 mediates rapid cutaneous wound healing., Vishnu Hosur, Lisa M. Burzenski, Timothy M Stearns, Michelle L Farley, John P Sundberg, Michael V. Wiles, and Leonard D. Shultz
Development of Humanized Mice in the Age of Genome Editing., Vishnu Hosur, Benjamin E. Low, Cindy Avery, Leonard D. Shultz, and Michael V. Wiles
Genetic deletion of amphiregulin restores the normal skin phenotype in a mouse model of the human skin disease tylosis., Vishnu Hosur, Benjamin E. Low, Leonard D. Shultz, and Michael V. Wiles
Tissue-specific role of RHBDF2 in cutaneous wound healing and hyperproliferative skin disease., Vishnu Hosur, Bonnie L. Lyons, Lisa M. Burzenski, and Leonard D. Shultz
NMDA Receptors Regulate the Development of Neuronal Intrinsic Excitability through Cell-Autonomous Mechanisms., Guoqiang Hou and Zhong-Wei Zhang
PRMT1-Mediated Translation Regulation Is a Crucial Vulnerability of Cancer., Jessie Hao-Ru Hsu, Benjamin Hubbell-Engler, Guillaume Adelmant, Jialiang Huang, Cailin E Joyce, Francisca Vazquez, Barbara A Weir, Philip Montgomery, Aviad Tsherniak, Andrew O Giacomelli, Jennifer A Perry, Jennifer J. Trowbridge, Yuko Fujiwara, Glenn S Cowley, Huafeng Xie, Woojin Kim, Carl D Novina, William C Hahn, Jarrod A Marto, and Stuart H Orkin
Interrogating the topological robustness of gene regulatory circuits by randomization., Bin Huang, Mingyang Lu, Dongya Jia, Eshel Ben-Jacob, Herbert Levine, and Jose N Onuchic
The role of Cdx2 as a lineage specific transcriptional repressor for pluripotent network during the first developmental cell lineage segregation., Daosheng Huang, Guoji Guo, Ping Yuan, Amy Ralston, Lingang Sun, Mikael Huss, Tapan Mistri, Luca Pinello, Huck Hui Ng, Guocheng Yuan, Junfeng Ji, Janet Rossant, Paul Robson, and Xiaoping Han
Revisiting the Warnock rule., J Benjamin Hurlbut, Insoo Hyun, Aaron D Levine, Robin Lovell-Badge, Jeantine E Lunshof, Kirstin R W Matthews, Peter Mills, Alison Murdoch, Martin Pera, Christopher Thomas Scott, Juliet Tizzard, Mary Warnock, Magdalena Zernicka-Goetz, Qi Zhou, and Laurie Zoloth
Multigene signature for predicting prognosis of patients with 1p19q co-deletion diffuse glioma., Xin Hu, Emmanuel Martinez-Ledesma, Siyuan Zheng, Hoon Kim, Floris P Barthel, Tao Jiang, Kenneth R Hess, and Roel G W Verhaak
SMC5/6 is required for the formation of segregation-competent bivalent chromosomes during meiosis I in mouse oocytes., Grace Hwang, Fengyun Sun, Marilyn J. O'Brien, John J. Eppig, Mary Ann Handel, and Philip W Jordan
Generating CRISPR mouse models: challenges and solutions., Rudolf Jaenisch and David S Grass
Genetic variation and gene expression across multiple tissues and developmental stages in a nonhuman primate., Anna J Jasinska, Ivette Zelaya, Susan K Service, Christine B Peterson, Rita M Cantor, Oi-Wa Choi, Joseph DeYoung, Eleazar Eskin, Lynn A Fairbanks, Scott Fears, Allison E Furterer, Yu S Huang, Vasily Ramensky, Christopher A Schmitt, Hannes Svardal, Matthew J Jorgensen, Jay R Kaplan, Diego Villar, Bronwen L Aken, Paul Flicek, Rishi Nag, Emily S Wong, John Blangero, Thomas D Dyer, Marina Bogomolov, Yoav Benjamini, George M. Weinstock, Ken Dewar, Chiara Sabatti, Richard K Wilson, J David Jentsch, Wesley Warren, Giovanni Coppola, Roger P Woods, and Nelson B Freimer
Effective biomedical document classification for identifying publications relevant to the mouse Gene Expression Database (GXD)., Xiangying Jiang, Martin Ringwald, Judith A. Blake, and Hagit Shatkay
Effects of Cdh23 single nucleotide substitutions on age-related hearing loss in C57BL/6 and 129S1/Sv mice and comparisons with congenic strains., Kenneth R. Johnson, Cong Tian, Leona H. Gagnon, Haiyan Jiang, Dalian Ding, and Richard Salvi
A Myc Activity Signature Predicts Poor Clinical Outcomes in Myc-Associated Cancers., MoonSun Jung, Amanda J Russell, Bing Liu, Joshy George, Pei Yan Liu, Tao Liu, Anna DeFazio, David D L Bowtell, André Oberthuer, Wendy B London, Jamie I Fletcher, Michelle Haber, Murray D Norris, and Michelle J Henderson
The influence of canalization on the robustness of Boolean networks, C Kadelka, J Kuipers, and Reinhard Laubenbacher
Prevalence of sexual dimorphism in mammalian phenotypic traits., Natasha A Karp, Jeremy Mason, Arthur L Beaudet, Yoav Benjamini, Lynette Bower, Robert E Braun, Steve D M Brown, Elissa J Chesler, Mary E Dickinson, Ann M Flenniken, Helmut Fuchs, Martin Hrabe de Angelis, Xiang Gao, Shiying Guo, Simon Greenaway, Ruth Heller, Yann Herault, Monica J Justice, Natalja Kurbatova, Christopher J Lelliott, K C Kent Lloyd, Ann-Marie Mallon, Judith E Mank, Hiroshi Masuya, Colin McKerlie, Terrence F Meehan, Richard F Mott, Stephen A. Murray, Helen Parkinson, Ramiro Ramirez-Solis, Luis Santos, John R Seavitt, Damian Smedley, Tania Sorg, Anneliese O Speak, Karen P Steel, Karen L. Svenson, Shigeharu Wakana, David West, Sara Wells, Henrik Westerberg, Shay Yaacoby, and Jacqueline K White
Modeling of Patient-Derived Xenografts in Colorectal Cancer., Anastasia Katsiampoura, Kanwal Raghav, Zhi-Qin Jiang, David G Menter, Andreas Varkaris, Maria P Morelli, Shanequa Manuel, Ji Wu, Alexey V Sorokin, Bahar Salimian Rizi, Christopher Bristow, Feng Tian, Susan Airhart, Mingshan Cheng, Bradley M Broom, Jeffrey Morris, Michael J Overman, Garth Powis, and Scott Kopetz
Cardiac regeneration: All work and no repair?, Teresa Kennedy-Lydon and Nadia Rosenthal