Content Posted in 2016
3D-GNOME: an integrated web service for structural modeling of the 3D genome., Przemyslaw Szalaj, Paul J Michalski, Przemysław Wróblewski, Zhonghui Tang, Michal Kadlof, Giovanni Mazzocco, Yijun Ruan, and Dariusz Plewczynski
A 380-gene meta-signature of active tuberculosis compared with healthy controls., Simon Blankley, Christine M Graham, Joe Levin, Jacob Turner, Matthew P R Berry, Chloe I Bloom, Zhaohui Xu, Virgina Pascual, Jacques Banchereau, Damien Chaussabel, Ronan Breen, George Santis, Derek M Blankenship, Marc Lipman, and Anne O'Garra
Abnormal response of distal Schwann cells to denervation in a mouse model of motor neuron disease., Dario I Carrasco, Ben A Bahr, Kevin L. Seburn, and Martin J Pinter
Absence of UCHL 1 function leads to selective motor neuropathy., Barış Genç, Javier H Jara, Megan C Schultz, Marin Manuel, Macdonell J Stanford, Mukesh Gautam, Jodi L Klessner, Gabriella Sekerkova, Daniel B Heller, Gregory A. Cox, Charles J Heckman, Christine J DiDonato, and P Hande Özdinler
ABT-414, an Antibody-Drug Conjugate Targeting a Tumor-Selective EGFR Epitope., Andrew C Phillips, Erwin R Boghaert, Kedar S Vaidya, Michael J Mitten, Suzanne Norvell, Hugh D Falls, Peter J DeVries, Dong Cheng, Jonathan A Meulbroek, Fritz G Buchanan, Laura M McKay, Neal C Goodwin, and Edward B Reilly
Accessing Data Resources in the Mouse Phenome Database for Genetic Analysis of Murine Life Span and Health Span., Molly A. Bogue, Luanne L. Peters, Beverly J Paigen, Ron Korstanje, Rong Yuan, Cheryl Ackert-Bicknell, Stephen C. Grubb, Gary A. Churchill, and Elissa J Chesler
Acetyl-L-Carnitine: a potential therapy for alleviation of the neurophysiological effects of Charcot-Marie-Tooth disease type 2D., Meagan Currie
A computational model of invasive aspergillosis in the lung and the role of iron., Matthew Oremland, Kathryn R Michels, Alexandra M Bettina, Chris Lawrence, Borna Mehrad, and Reinhard Laubenbacher
Activation of GCN2 kinase by ribosome stalling links translation elongation with translation initiation., Ryuta Ishimura, Gabor Nagy, Ivan Dotu, Jeffrey H Chuang, and Susan L. Ackerman
Addressing intra-tumoral heterogeneity and therapy resistance., Brad Rybinski and Kyuson Yun
A Glimpse of Microbial Power in Preventive Medicine., George M. Weinstock
A Humanized Mouse Model to Study Human Albumin and Albumin Conjugates Pharmacokinetics., Benjamin E. Low and Michael V. Wiles
A hypomorphic mutation of the gamma-1 adaptin gene (Ap1g1) causes inner ear, retina, thyroid, and testes abnormalities in mice., Kenneth R. Johnson, Leona H. Gagnon, and Bo Chang
AlgoRun: a Docker-based packaging system for platform-agnostic implemented algorithms., Abdelrahman Hosny, Paola Vera-Licona, Reinhard Laubenbacher, and Thibauld Favre
A link between planar polarity and staircase-like bundle architecture in hair cells., Basile Tarchini, Abby Tadenev, Nicholas Devanney, and Michel Cayouette
Alternate-locus aware variant calling in whole genome sequencing., Marten Jäger, Max Schubach, Tomasz Zemojtel, Knut Reinert, Deanna M Church, and Peter N Robinson
Amplification of the bromodomain-containing protein 4 gene in ovarian high-grade serous carcinoma is associated with worse prognosis and survival., Duygu Ucar and Douglas I Lin
Analysis of Expression Pattern and Genetic Deletion of Netrin5 in the Developing Mouse., Andrew M. Garrett, Thomas J. Jucius, Liam P R Sigaud, Fu-Lei Tang, Wen-Cheng Xiong, Susan L. Ackerman, and Robert W. Burgess
Analysis of morphine responses in mice reveals a QTL on Chromosome 7., Wim E Crusio, Esha Dhawan, Elissa J Chesler, and Anna Delprato
Analysis of Transcriptional Signatures in Response to Listeria monocytogenes Infection Reveals Temporal Changes That Result from Type I Interferon Signaling., Jonathan M Pitt, Simon Blankley, Krzysztof Potempa, Christine M Graham, Lucia Moreira-Teixeira, Finlay W McNab, Ashleigh Howes, Evangelos Stavropoulos, Virginia Pascual, Jacques Banchereau, Damien Chaussabel, and Anne O'Garra
Anatomical and Gene Expression Changes in the Retinal Pigmented Epithelium Atrophy 1 (rpea1) Mouse: A Potential Model of Serous Retinal Detachment., Gabriel Luna, Geoffrey P Lewis, Kenneth A Linberg, Bo Chang, Quiri Hu, Peter J Munson, Arvydas Maminishkis, Sheldon S Miller, and Steven K Fisher
Angiogenesis in the skin of SHARPIN-deficient mice with chronic proliferative dermatitis., Harm HogenEsch, Mario Sola, Timothy M Stearns, Kathleen A Silva, Victoria E. Kennedy, and John P Sundberg
Angiopoietin receptor TEK mutations underlie primary congenital glaucoma with variable expressivity., Tomokazu Souma, Stuart W Tompson, Benjamin R Thomson, Owen M Siggs, Krishnakumar Kizhatil, Shinji Yamaguchi, Liang Feng, Vachiranee Limviphuvadh, Kristina N Whisenhunt, Sebastian Maurer-Stroh, Tammy L Yanovitch, Luba Kalaydjieva, Dimitar N Azmanov, Simone Finzi, Lucia Mauri, Shahrbanou Javadiyan, Emmanuelle Souzeau, Tiger Zhou, Alex W Hewitt, Bethany Kloss, Kathryn P Burdon, David A Mackey, Keri F Allen, Jonathan B Ruddle, Sing-Hui Lim, Steve Rozen, Khanh-Nhat Tran-Viet, Xiaorong Liu, Simon W M John, Janey L Wiggs, Francesca Pasutto, Jamie E Craig, Jing Jin, Susan E Quaggin, and Terri L Young
Animal-based studies will be essential for precision medicine., K C Kent Lloyd, Peter N Robinson, and Calum A MacRae
An inquiry into the causes and effects of the variolae (or Cow-pox. 1798)., Alfred B Jenson, Shin-Je Ghim, and John P Sundberg
An integrated 3-Dimensional Genome Modeling Engine for data-driven simulation of spatial genome organization., Przemysław Szałaj, Zhonghui Tang, Paul Michalski, Michal J Pietal, Oscar Junhong Luo, Michał Sadowski, Xingwang Li, Kamen Radew, Yijun Ruan, and Dariusz Plewczynski
An Integrative Approach to Precision Cancer Medicine Using Patient-Derived Xenografts., Sung-Yup Cho, Wonyoung Kang, Jee Yun Han, Seoyeon Min, Jinjoo Kang, Ahra Lee, Jee Young Kwon, Charles Lee, and Hansoo Park
An In Vitro Perfusion System to Enhance Outflow Studies in Mouse Eyes., Krishnakumar Kizhatil, Arthur Chlebowski, Nicholas G Tolman, Nelson F Freeburg, Margaret M Ryan, Nicholas N Shaw, Alexander D M Kokini, Jeffrey K Marchant, and Simon W M John
A novel conditional mouse model for Nkx2-5 reveals transcriptional regulation of cardiac ion channels., Milena B Furtado, Julia C Wilmanns, Anjana Chandran, Mary Tonta, Christine Biben, Michael Eichenlaub, Harold A Coleman, Silke Berger, Romaric Bouveret, Reena Singh, Richard P Harvey, Mirana Ramialison, James T Pearson, Helena C Parkington, Nadia A. Rosenthal, and Mauro W Costa
A novel Cux1 CRISPR-Cas9 knockout system to study mesangial matrix expansion in mouse kidney cells., Demetri Maxim
A Patient-Derived Xenograft Model of Parameningeal Embryonal Rhabdomyosarcoma for Preclinical Studies., Jody E Hooper, Emma L Cantor, Macgregor S Ehlen, Avirup Banerjee, Suman Malempati, Peter Stenzel, Randy L Woltjer, Regina Gandour-Edwards, Neal C Goodwin, Yan Yang, Pali Kaur, Carol J Bult, Susan Airhart, and Charles Keller
A pipeline to discover new genes involved in Cochlear hair cell differentiation., Lawrence Jacobs
Application of Mouse Models to Research in Hearing and Balance., Kevin K Ohlemiller, Sherri M Jones, and Kenneth R. Johnson
Approaches to Investigating Complex Genetic Traits in a Large-Scale Inbred Mouse Aging Study., John P Sundberg, A Berndt, Beth A. Sundberg, Kathleen A Silva, Victoria E. Kennedy, R S Smith, T K Cooper, and P N Schofield
Array-Based Comparative Genomic Hybridization (aCGH)., Chengsheng Zhang, Eliza Cerveira, Mallory Romanovitch, and Qihui Zhu
A Salmonella nanoparticle mimic overcomes multidrug resistance in tumours., Regino Mercado-Lubo, Yuanwei Zhang, Liang Zhao, Kyle Rossi, Xiang Wu, Yekui Zou, Antonio Castillo, Jack Leonard, Rita Bortell, Dale L Greiner, Leonard D. Shultz, Gang Han, and Beth A McCormick
Assessment of hepatic insulin signaling in a murine model for Alstrom Syndrome., Ayla Kanber
Assessment of the Readability of Genetic Counseling Patient Letters., Emily Brown, Megan Skinner, Stephanie Ashley, Kate Reed, and Shannan DeLany Dixon
Autoimmune manifestations in aged mice arise from early-life immune dysregulation., Tamer I Mahmoud, Jingya Wang, Jodi L Karnell, Qiming Wang, Shu Wang, Brian Naiman, Phillip Gross, Philip Z Brohawn, Chris Morehouse, Jordan Aoyama, Clive Wasserfall, Laura Carter, Mark A Atkinson, David V. Serreze, Helen Braley-Mullen, Tomas Mustelin, Roland Kolbeck, Ronald Herbst, and Rachel Ettinger
Azithromycin therapy during respiratory syncytial virus bronchiolitis: Upper airway microbiome alterations and subsequent recurrent wheeze., Yanjiao Zhou, Leonard B Bacharier, Megan Isaacson-Schmid, Jack Baty, Kenneth B Schechtman, Geneline Sajol, Kristine Wylie, Gregory A Storch, Mario Castro, and Avraham Beigelman
Beyond the brain: disrupted in schizophrenia 1 regulates pancreatic β-cell function via glycogen synthase kinase-3β., Agata Jurczyk, Anetta Nowosielska, Natalia Przewozniak, Ken-Edwin Aryee, Philip DiIorio, David Blodgett, Chaoxing Yang, Martha Campbell-Thompson, Mark Atkinson, Leonard D. Shultz, Ann Rittenhouse, David Harlan, Dale Greiner, and Rita Bortell
Bioprinting towards Physiologically Relevant Tissue Models for Pharmaceutics., Weijie Peng, Derya Unutmaz, and Ibrahim T Ozbolat
Block network mapping approach to quantitative trait locus analysis., Zeina Z Shreif, Daniel Mario Gatti, and Vipul Periwal
B-lymphocytes expressing an immunoglobulin specificity recognizing the pancreatic ß-cell autoantigen peripherin are potent contributors to type 1 diabetes development in NOD mice., Caroline M. Leeth, Jeremy Racine, Harold D. Chapman, Berta Arpa, Jorge Carrillo, Jorge Carrascal, Qiming Wang, Jeremy Ratiu, Leire Egia-Mendikute, Estela Rosell-Mases, Thomas Stratmann, Joan Verdaguer, and David V. Serreze
Bridging channel dendritic cells induce immunity to transfused red blood cells., Samuele Calabro, Antonia Gallman, Uthaman Gowthaman, Dong Liu, Pei Chen, Jingchun Liu, Jayendra Kumar Krishnaswamy, Manuela Sales L Nascimento, Lan Xu, Seema R Patel, Adam Williams, Christopher A Tormey, Eldad A Hod, Steven L Spitalnik, James C Zimring, Jeanne E Hendrickson, Sean R Stowell, and Stephanie C Eisenbarth
Bridging Mice to Men: Using HLA Transgenic Mice to Enhance the Future Prediction and Prevention of Autoimmune Type 1 Diabetes in Humans., David V. Serreze, Marijke Niens, John Kulik, and Teresa P DiLorenzo
Bright-Field Imaging and Optical Coherence Tomography of the Mouse Posterior Eye., Mark P Krebs, Mei Xiao, Keith Sheppard, Wanda L. Hicks, and Patsy M. Nishina
C1q propagates microglial activation and neurodegeneration in the visual axis following retinal ischemia/reperfusion injury., Sean M Silverman, Byung-Jin Kim, Gareth R Howell, Joselyn Miller, Simon W M John, Robert J Wordinger, and Abbot F Clark
C9orf72 is required for proper macrophage and microglial function in mice., J G O'Rourke, Laurent P. Bogdanik, A Yáñez, D Lall, A J Wolf, A K M G Muhammad, R Ho, S Carmona, J P Vit, J Zarrow, K J Kim, S Bell, M B Harms, T M Miller, C A Dangler, D M Underhill, H S Goodridge, Cathleen Lutz, and R H Baloh
Cardiac regeneration: epicardial mediated repair., Teresa Kennedy-Lydon and Nadia Rosenthal
Cardiovascular Research and the Laboratory Mouse, Ray Lambert
Casilio: a versatile CRISPR-Cas9-Pumilio hybrid for gene regulation and genomic labeling., Albert W. Cheng, Nathaniel L. Jillette, Phoebe Lee, Dylan Plaskon, Yasuhiro Fujiwara, Wenbo Wang, Aziz Taghbalout, and Haoyi Wang
Cell cycle and survival status of erythroid precursors in the Nan mouse model., Omorose Aighewi
Cell-Extrinsic MHC Class I Molecule Engagement Augments Human NK Cell Education Programmed by Cell-Intrinsic MHC Class I., Jeanette E Boudreau, Xiao-Rong Liu, Zeguo Zhao, Aaron Zhang, Leonard D. Shultz, Dale L Greiner, Bo Dupont, and Katharine C Hsu
Changes in the expression of splicing factor transcripts and variations in alternative splicing are associated with lifespan in mice and humans., Benjamin P Lee, Luke C Pilling, Florence Emond, Kevin Flurkey, David E Harrison, Rong Yuan, Luanne L. Peters, George A Kuchel, Luigi Ferrucci, David Melzer, and Lorna W Harries
Characterization of the bacterial and fungal microbiome in indoor dust and outdoor air samples: a pilot study., Blake M Hanson, Yanjiao Zhou, Eddy J Bautista, Bruce Urch, Mary Speck, Frances Silverman, Michael Muilenberg, Wanda Phipatanakul, George M. Weinstock, Erica Sodergren Weinstock, Diane R Gold, and Joanne E Sordillo
Chromosomal Instability Affects the Tumorigenicity of Glioblastoma Tumor-Initiating Cells., Kristina M Godek, Monica Venere, Quilian Wu, Kevin D Mills, William F Hickey, Jeremy N Rich, and Duane A Compton
Chronic consumption of a western diet induces robust glial activation in aging mice and in a mouse model of Alzheimer's disease., Leah C. Graham, Jeffrey M. Harder, Ileana Soto, Wilhelmine N de Vries, Simon W M John, and Gareth R Howell
Clinical Trials in Precision Oncology., Susan Mockus, Sara E. Patterson, Cara M. Statz, Carol J Bult, and Gregory J Tsongalis
Col4a1 mutations cause progressive retinal neovascular defects and retinopathy., Marcel V Alavi, Mao Mao, Bradley T Pawlikowski, Manana Kvezereli, Jacque L Duncan, Richard T Libby, Simon W M John, and Douglas B Gould
Combined B, T and NK Cell Deficiency Accelerates Atherosclerosis in BALB/c Mice., Fei Cheng, Laura Twardowski, Kurt Reifenberg, Kerstin Winter, Antje Canisius, Eva Pross, Jianglin Fan, Edgar Schmitt, Leonard D. Shultz, Karl J Lackner, and Michael Torzewski
Comparative transcriptomic profiling of hydrogen peroxide signaling networks in zebrafish and human keratinocytes: Implications toward conservation, migration and wound healing., Thomas S Lisse, Benjamin L King, and Sandra Rieger
Comparison of the acute ultraviolet photoresponse in congenic albino hairless C57BL/6J mice relative to outbred SKH1 hairless mice., Raymond L Konger, Ethel Derr-Yellin, Delaram Hojati, Cathleen Lutz, and John P Sundberg
Computational inference of a genomic pluripotency signature in human and mouse stem cells., Esra Kurum, Bérénice A Benayoun, Ankit Malhotra, Joshy George, and Duygu Ucar
Computational inference of H3K4me3 and H3K27ac domain length., Julian Zubek, Michael L. Stitzel, Duygu Ucar, and Dariusz M Plewczynski
Crim1 regulates integrin signaling in murine lens development., Ying Zhang, Jieqing Fan, Joshua W K Ho, Tommy Hu, Stephen C Kneeland, Xueping Fan, Qiongchao Xi, Michael A Sellarole, Wilhelmine N de Vries, Weining Lu, Salil A Lachke, Richard A Lang, Simon W M John, and Richard L Maas
CRIPT exonic deletion and a novel missense mutation in a female with short stature, dysmorphic features, microcephaly, and pigmentary abnormalities., Magalie S Leduc, Zhiyv Niu, Weimin Bi, Wenmiao Zhu, Irene Miloslavskaya, Theodore Chiang, Haley Streff, John R Seavitt, Stephen A Murray, Christine Eng, Audrey Chan, Yaping Yang, and Seema R Lalani
Cross-Species Integrative Functional Genomics in GeneWeaver Reveals a Role for Pafah1b1 in Altered Response to Alcohol., Jason A. Bubier, Troy Wilcox, Jeremy Jay, Michael A Langston, Erich J Baker, and Elissa J Chesler
Current state of pediatric sarcoma biology and opportunities for future discovery: A report from the sarcoma translational research workshop., Pooja Hingorani, Katherine Janeway, Brian D Crompton, Cigall Kadoch, Crystal L Mackall, Javed Khan, Jack F Shern, Joshua Schiffman, Lisa Mirabello, Sharon A Savage, Marc Ladanyi, Paul Meltzer, Carol J Bult, Peter C Adamson, Philip J Lupo, Rajen Mody, Steven G DuBois, D Williams Parsons, Chand Khanna, Ching Lau, Douglas S Hawkins, R Lor Randall, Malcolm Smith, Poul H Sorensen, Sharon E Plon, Stephen X Skapek, Stephen Lessnick, Richard Gorlick, and Damon R Reed
Defining the consequences of genetic variation on a proteome-wide scale., Joel M Chick, Steven C. Munger, Petr Simecek, Edward L Huttlin, Kwangbom Choi, Daniel M. Gatti, Narayanan Raghupathy, Karen L. Svenson, Gary Churchill, and Steven P Gygi
Delivery of Cas9 Protein into Mouse Zygotes through a Series of Electroporation Dramatically Increases the Efficiency of Model Creation., Wenbo Wang, Peter M Kutny, Shannon L. Byers, Charles J Longstaff, Michael J DaCosta, Changhong Pang, Yingfan Zhang, Robert A. Taft, F William Buaas, and Haoyi Wang
De novo frameshift mutation in COUP-TFII (NR2F2) in human congenital diaphragmatic hernia., Frances A High, Pooja Bhayani, Jay M Wilson, Carol J Bult, Patricia K Donahoe, and Mauro Longoni
Dermal lymphatic dilation in a mouse model of alopecia areata., John P Sundberg, C Herbert Pratt, Kathleen A Silva, Victoria E. Kennedy, Timothy M Stearns, Beth A. Sundberg, Lloyd E King, and Harm HogenEsch
DermO; an ontology for the description of dermatologic disease., Hannah M Fisher, Robert Hoehndorf, Bruno S Bazelato, Soheil S Dadras, Lloyd E King, Georgios V Gkoutos, John P Sundberg, and Paul N Schofield
Development-on-chip: in vitro neural tube patterning with a microfluidic device., Christopher J Demers, Prabakaran Soundararajan, Phaneendra Chennampally, Gregory A. Cox, James Briscoe, Scott D Collins, and Rosemary L Smith
Differential Intrasplenic Migration of Dendritic Cell Subsets Tailors Adaptive Immunity., Samuele Calabro, Dong Liu, Antonia Gallman, Manuela Sales L Nascimento, Zizi Yu, Ting-Ting Zhang, Pei Chen, Biyan Zhang, Lan Xu, Uthaman Gowthaman, Jayendra Kumar Krishnaswamy, Ann M Haberman, Adam Williams, and Stephanie C Eisenbarth
Discovery and characterization of spontaneous mouse models of craniofacial dysmorphology., Kristina Palmer, Heather Fairfield, Suhaib Borgeia, Michelle Curtain, Mohamed G Hassan, Louise A. Dionne, Son Yong Karst, Harold Coombs, Roderick T Bronson, Laura G Reinholdt, David E. Bergstrom, Leah Rae Donahue, Timothy C Cox, and Stephen A Murray
Discovery of enriched variants for Alzheimer's disease., Carl Vitzthum
Distinct Differences on Neointima Formation in Immunodeficient and Humanized Mice after Carotid or Femoral Arterial Injury., Jill Moser, Joris van Ark, Marcory C van Dijk, Dale L Greiner, Leonard D. Shultz, Harry van Goor, and Jan-Luuk Hillebrands
Diversity and collaboration for effective immunotherapy., Karolina Palucka and Jacques Banchereau
Diversity Exiting the Academy: Influential Factors for the Career Choice of Well-Represented and Underrepresented Minority Scientists., Rebekah L Layton, Patrick D Brandt, Ashalla M Freeman, Jessica R Harrell, Joshua D Hall, and Melanie Sinche
Diversity Outbred Mice at 21: Maintaining Allelic Variation in the Face of Selection., Elissa J Chesler, Daniel Mario Gatti, Andrew P Morgan, Marjorie Strobel, Laura Trepanier, Denesa Oberbeck, Shannon McWeeney, Robert Hitzemann, Martin Ferris, Rachel McMullan, Amelia Clayshultle, Timothy A Bell, Fernando Pardo Manuel de Villena, and Gary A. Churchill
DNA Damage-Inducible Transcript 4 Is an Innate Surveillant of Hair Follicular Stress in Vitamin D Receptor Knockout Mice and a Regulator of Wound Re-Epithelialization., Hengguang Zhao, Sandra Rieger, Koichiro Abe, Martin Hewison, and Thomas S Lisse
Draft Genome Sequence of Cloacibacterium normanense NRS-1 Isolated from Municipal Wastewater., Nicole R Gay, Elizabeth Fleming, and Julia Oh
DSCAM and DSCAML1 molecular mechanisms of self avoidance., Julia Bassell
Dual Effects of Bisphosphonates on Ectopic Skin and Vascular Soft Tissue Mineralization versus Bone Microarchitecture in a Mouse Model of Generalized Arterial Calcification of Infancy., Qiaoli Li, Joshua Kingman, John P Sundberg, Michael A Levine, and Jouni Uitto
Dynamin 1 isoform roles in a mouse model of severe childhood epileptic encephalopathy., Samuel Asinof, Connie L Mahaffey, Barbara Beyer, Wayne N Frankel, and Rebecca M. Boumil
Ebola Virus Replication and Disease Without Immunopathology in Mice Expressing Transgenes to Support Human Myeloid and Lymphoid Cell Engraftment., Jessica R Spengler, Kerry J Lavender, Cynthia Martellaro, Aaron Carmody, Andreas Kurth, James G. Keck, Greg Saturday, Dana P Scott, Stuart T Nichol, Kim J Hasenkrug, Christina F Spiropoulou, Heinz Feldmann, and Joseph Prescott
Ectopic expression of ceramide synthase 2 in neurons suppresses neurodegeneration induced by ceramide synthase 1 deficiency., Stefka D Spassieva, Xiaojie Ji, Ye Liu, Kenneth Gable, Jacek Bielawski, Teresa M Dunn, Erhard Bieberich, and Lihong Zhao
Ectopic Mineralization and Conductive Hearing Loss in Enpp1asj Mutant Mice, a New Model for Otitis Media and Tympanosclerosis., Cong Tian, Belinda S. Harris, and Kenneth R. Johnson
Ectopic mineralization of cartilage and collagen-rich tendons and ligaments in Enpp1asj-2J mice., Jieyu Zhang, Nathaniel A Dyment, David W Rowe, Sarah Y Siu, John P Sundberg, Jouni Uitto, and Qiaoli Li
Editing the Mouse Genome Using the CRISPR-Cas9 System., Adam Williams, Jorge Henao-Mejia, and Richard A Flavell
Effect of Advanced HIV Infection on the Respiratory Microbiome., Homer L Twigg, Kenneth S Knox, Jin Zhou, Kristina A Crothers, David E Nelson, Evelyn Toh, Richard B Day, Huaiying Lin, Xiang Gao, Qunfeng Dong, Deming Mi, Barry P Katz, Erica Sodergren Weinstock, and George M. Weinstock
Effect of genetic background on the dystrophic phenotype in mdx mice., William D Coley, Laurent P. Bogdanik, Maria Candida Vila, Qing Yu, Jack H Van Der Meulen, Sree Rayavarapu, James S Novak, Marie Nearing, James L Quinn, Allison Saunders, Connor Dolan, Whitney Andrews, Catherine Lammert, Andrew Austin, Terence A Partridge, Gregory A. Cox, Cathleen Lutz, and Kanneboyina Nagaraju
Effects of Varied Housing Density on a Hybrid Mouse Strain Followed for 20 Months., Beverly Paigen, Joanne M Currer, and Karen L. Svenson
Effects of Walnut Consumption on Colon Carcinogenesis and Microbial Community Structure., Masako Nakanishi, Yanfei Chen, Veneta Qendro, Shingo Miyamoto, Erica Sodergren Weinstock, George M. Weinstock, and Daniel W Rosenberg
Efficient and Targeted Transduction of Nonhuman Primate Liver With Systemically Delivered Optimized AAV3B Vectors., Shaoyong Li, Chen Ling, Li Zhong, Mengxin Li, Qin Su, Ran He, Qiushi Tang, Dale L Greiner, Leonard D. Shultz, Michael A Brehm, Terence R Flotte, Christian Mueller, Arun Srivastava, and Guangping Gao
Elucidating the function of Yap in normal and cancer stem cells in the brain., Xingyao Chen
Engineering microdeletions and microduplications by targeting segmental duplications with CRISPR., Derek J C Tai, Ashok Ragavendran, Poornima Manavalan, Alexei Stortchevoi, Catarina M Seabra, Serkan Erdin, Ryan L Collins, Ian Blumenthal, Xiaoli Chen, Yiping Shen, Mustafa Sahin, Chengsheng Zhang, Charles Lee, James F Gusella, and Michael E Talkowski
Enhancing the versatility of wireless biopotential acquisition for myoelectric prosthetic control., Rebecca A Bercich, Zhi Wang, Henry Mei, Lauren H Hammer, Kevin L. Seburn, Levi J Hargrove, and Pedro P Irazoqui
Epileptic encephalopathy-causing mutations in DNM1 impair synaptic vesicle endocytosis., Ryan S Dhindsa, Shelton S Bradrick, Xiaodi Yao, Erin L Heinzen, Slave Petrovski, Brian J Krueger, Michael R Johnson, Wayne N Frankel, Steven Petrou, Rebecca M. Boumil, and David B Goldstein
Eric Lander and David Botstein on Mapping Quantitative Traits., Gary A. Churchill
Examining the antitumor activity of a monoclonal antibody via complement-dependent cytotoxicity in novel NSG mouse model., Julia Clemens
Examining the role of inhibitory GABAergic neurons in the pathophysiology of Rett Syndrome., Kevin Newhall
Expansion and Activation of CD103(+) Dendritic Cell Progenitors at the Tumor Site Enhances Tumor Responses to Therapeutic PD-L1 and BRAF Inhibition., Hélène Salmon, Juliana Idoyaga, Adeeb Rahman, Marylène Leboeuf, Romain Remark, Stefan Jordan, Maria Casanova-Acebes, Makhzuna Khudoynazarova, Judith Agudo, Navpreet Tung, Svetoslav Chakarov, Christina Rivera, Brandon Hogstad, Marcus Bosenberg, Daigo Hashimoto, Sacha Gnjatic, Nina Bhardwaj, Karolina Palucka, Brian D Brown, Joshua Brody, Florent Ginhoux, and Miriam Merad
Exploring the genetic mechanisms of exfoliation syndrome and glaucoma., Annie Gagnon
FOXP3+Helios+ Regulatory T Cells, Immune Activation, and Advancing Disease in HIV-Infected Children., Alka Khaitan, Adam Kravietz, Mussa Mwamzuka, Fatma Marshed, Tiina Ilmet, Swalehe Said, Aabid Ahmed, William Borkowsky, and Derya Unutmaz
Gene activation through enhancer epigenetic modifications using Casilio, a three-hybrid CRISPRzyme system., Phoebe Lee
Generating Mouse Models Using CRISPR-Cas9-Mediated Genome Editing., Wenning Qin, Peter Kutny, Richard S. Maser, Stephanie L. Dion, Jeffrey D Lamont, Yingfan Zhang, Greggory A Perry, and Haoyi Wang
Generation of Genetically Modified Mice Using the CRISPR-Cas9 Genome-Editing System., Jorge Henao-Mejia, Adam Williams, Anthony Rongvaux, Judith Stein, Cynthia Hughes, and Richard A Flavell
Generation of Immunodeficient Mice Bearing Human Immune Systems by the Engraftment of Hematopoietic Stem Cells., Suheyla Hasgur, Ken Edwin Aryee, Leonard D. Shultz, Dale L Greiner, and Michael A Brehm
Gene regulation knowledge commons: community action takes care of DNA binding transcription factors., Sushil Tripathi, Steven Vercruysse, Konika Chawla, Karen R. Christie, Judith A. Blake, Rachael P Huntley, Sandra Orchard, Henning Hermjakob, Liv Thommesen, Astrid Lægreid, and Martin Kuiper
Genetic ablation of lymphocytes and cytokine signaling in nonobese diabetic mice prevents diet-induced obesity and insulin resistance., Randall H Friedline, Hwi Jin Ko, Dae Young Jung, Yongjin Lee, Rita Bortell, Sezin Dagdeviren, Payal R Patel, Xiaodi Hu, Kunikazu Inashima, Caitlyn Kearns, Nicholas Tsitsilianos, Umber Shafiq, Leonard D. Shultz, Ki Won Lee, Dale L Greiner, and Jason K Kim
Genetically modified human CD4(+) T cells can be evaluated in vivo without lethal graft-versus-host disease., Riyasat Ali, Jeffrey Babad, Antonia Follenzi, John A Gebe, Michael A Brehm, Gerald T Nepom, Leonard D. Shultz, Dale L Greiner, and Teresa P DiLorenzo
Genetic and tissue level muscle-bone interactions during unloading and reambulation., S Judex, W Zhang, Leah Rae Donahue, and E Ozcivici
Genetic Architectures of Quantitative Variation in RNA Editing Pathways., Tongjun Gu, Daniel Mario Gatti, Anuj Srivastava, Elizabeth M Snyder, Narayanan Raghupathy, Petr Simecek, Karen L. Svenson, Ivan Dotu, Jeffrey H Chuang, Mark P Keller, Alan D Attie, Robert E Braun, and Gary A Churchill
Genetic determinants of fibro-osseous lesions in aged inbred mice., Annerose Berndt, Cheryl Ackert-Bicknell, Kathleen A Silva, Victoria E. Kennedy, Beth A. Sundberg, Justin M Cates, Paul N Schofield, and John P Sundberg
Genetic identification of thiosulfate sulfurtransferase as an adipocyte-expressed antidiabetic target in mice selected for leanness., Nicholas M Morton, Jasmina Beltram, Roderick N Carter, Zoi Michailidou, Gregor Gorjanc, Clare McFadden, Martin E Barrios-Llerena, Sergio Rodriguez-Cuenca, Matthew T G Gibbins, Rhona E Aird, José Maria Moreno-Navarrete, Steven C. Munger, Karen L. Svenson, Annalisa Gastaldello, Lynne Ramage, Gregorio Naredo, Maximilian Zeyda, Zhao V Wang, Alexander F Howie, Aila Saari, Petra Sipilä, Thomas M Stulnig, Vilmundur Gudnason, Christopher J Kenyon, Jonathan R Seckl, Brian R Walker, Scott P Webster, Donald R Dunbar, Gary A Churchill, Antonio Vidal-Puig, José Manuel Fernandez-Real, Valur Emilsson, and Simon Horvat
Genetic Interactions Between the Meiosis-Specific Cohesin Components, STAG3, REC8, and RAD21L., Ayobami Ward, Jessica Hopkins, Matthew Mckay, Stephen A Murray, and Philip W Jordan
GeneWeaver: data driven alignment of cross-species genomics in biology and disease., Erich Baker, Jason A. Bubier, Timothy Reynolds, Michael A Langston, and Elissa J Chesler
Genome-wide association analysis identifies TXNRD2, ATXN2 and FOXC1 as susceptibility loci for primary open-angle glaucoma., Jessica N Cooke Bailey, Stephanie J Loomis, Jae H Kang, R Rand Allingham, Puya Gharahkhani, Chiea Chuen Khor, Kathryn P Burdon, Hugues Aschard, Daniel I Chasman, Robert P Igo, Pirro G Hysi, Craig A Glastonbury, Allison Ashley-Koch, Murray Brilliant, Andrew A Brown, Donald L Budenz, Alfonso Buil, Ching-Yu Cheng, Hyon Choi, William G Christen, Gary Curhan, Immaculata De Vivo, John H Fingert, Paul J Foster, Charles Fuchs, Douglas Gaasterland, Terry Gaasterland, Alex W Hewitt, Frank Hu, David J Hunter, Anthony P Khawaja, Richard K Lee, Zheng Li, Paul R Lichter, David A Mackey, Peter McGuffin, Paul Mitchell, Sayoko E Moroi, Shamira A Perera, Keating W. Pepper, Qibin Qi, Tony Realini, Julia E Richards, Paul M Ridker, Eric Rimm, Robert Ritch, Marylyn Ritchie, Joel S Schuman, William K Scott, Kuldev Singh, Arthur J Sit, Yeunjoo E Song, Rulla M Tamimi, Fotis Topouzis, Ananth C Viswanathan, Shefali Setia Verma, Douglas Vollrath, Jie Jin Wang, Nicole Weisschuh, Bernd Wissinger, Gadi Wollstein, Tien Y Wong, Brian L Yaspan, Donald J Zack, Kang Zhang, Epic-Norfolk Eye Study, Robert N Weinreb, Margaret A Pericak-Vance, Kerrin Small, Christopher J Hammond, Tin Aung, Yutao Liu, Eranga N Vithana, Stuart MacGregor, Jamie E Craig, Peter Kraft, Gareth R Howell, Michael A Hauser, Louis R Pasquale, Jonathan L Haines, and Janey L Wiggs
Gnaq(M1J): An ENU-Induced Mutant Allele Affecting Pigmentation in the Mouse., C Herbert Pratt, Louise A. Dionne, Heather Fairfield, Soheil S Dadras, Christopher S Potter, and John P Sundberg
Guidelines for the functional annotation of microRNAs using the Gene Ontology., Rachael P Huntley, Dmitry Sitnikov, Marija Orlic-Milacic, Rama Balakrishnan, Peter D'Eustachio, Marc E Gillespie, Doug Howe, Anastasia Z Kalea, Lars Maegdefessel, David Osumi-Sutherland, Victoria Petri, Jennifer R Smith, Kimberly Van Auken, Valerie Wood, Anna Zampetaki, Manuel Mayr, and Ruth C Lovering
Gut bacteria dysbiosis and necrotising enterocolitis in very low birthweight infants: a prospective case-control study., Barbara B Warner, Elena Deych, Yanjiao Zhou, Carla Hall-Moore, George M. Weinstock, Erica Sodergren Weinstock, Nurmohammad Shaikh, Julie A Hoffmann, Laura A Linneman, Aaron Hamvas, Geetika Khanna, Lucina C Rouggly-Nickless, I Malick Ndao, Berkley A Shands, Marilyn Escobedo, Janice E Sullivan, Paula G Radmacher, William D Shannon, and Phillip I Tarr
Health and population effects of rare gene knockouts in adult humans with related parents., Vagheesh M Narasimhan, Karen A Hunt, Dan Mason, Christopher L. Baker, Konrad J Karczewski, Michael R Barnes, Anthony H Barnett, Chris Bates, Srikanth Bellary, Nicholas A Bockett, Kristina Giorda, Christopher J Griffiths, Harry Hemingway, Zhilong Jia, M Ann Kelly, Hajrah A Khawaja, Monkol Lek, Shane McCarthy, Rosie McEachan, Anne O'Donnell-Luria, Kenneth Paigen, Constantinos A Parisinos, Eamonn Sheridan, Laura Southgate, Louise Tee, Mark Thomas, Yali Xue, Michael Schnall-Levin, Petko M. Petkov, Chris Tyler-Smith, Eamonn R Maher, Richard C Trembath, Daniel G MacArthur, John Wright, Richard Durbin, and David A van Heel
Heritability of in vitro phenotypes exhibited by murine adipose-derived stromal cells., Zixuan Jiang, David E Harrison, Makayla E Parsons, Susan McClatchy, Lawrence Jacobs, and Robert Pazdro
High-throughput discovery of novel developmental phenotypes., Mary E Dickinson, Ann M Flenniken, Xiao Ji, Lydia Teboul, Michael D Wong, Jacqueline K White, Terrence F Meehan, Wolfgang J Weninger, Henrik Westerberg, Hibret Adissu, Candice N Baker, Lynette Bower, James M Brown, L Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R Horner, Chih-Wei Hsu, Sara J Johnson, Sowmya Kalaga, Lance C Keith, Louise Lanoue, Thomas N Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L McElwee, Susan Newbigging, Lauryl M J Nutter, Kevin A Peterson, Ramiro Ramirez-Solis, Douglas J Rowland, Edward Ryder, Kaitlin E Samocha, John R Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B West, Leeyean Wong, Atsushi Yoshiki, Daniel G MacArthur, Glauco P Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C Skarnes, Monica J Justice, Helen E Parkinson, Mark Moore, Sara Wells, Robert E Braun, Karen L Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R Mark Henkelman, Steve D M Brown, David J Adams, K C Kent Lloyd, Colin McKerlie, Arthur L Beaudet, Maja Bućan, and Stephen A Murray
HIV-Infected Children Have Lower Frequencies of CD8+ Mucosal-Associated Invariant T (MAIT) Cells that Correlate with Innate, Th17 and Th22 Cell Subsets., Alka Khaitan, Max Kilberg, Adam Kravietz, Tiina Ilmet, Cihan Tastan, Mussa Mwamzuka, Fatma Marshed, Mengling Liu, Aabid Ahmed, William Borkowsky, and Derya Unutmaz
Honoring the work and life of Leroy C. Stevens. A symposium as part of the International Stem Cell Initiative Workshop., Christopher F Graham, Davor Solter, John D Gearhart, Joseph H Nadeau, and Barbara B. Knowles
Household air pollution and the lung microbiome of healthy adults in Malawi: a cross-sectional study., Jamie Rylance, Anstead Kankwatira, David E Nelson, Evelyn Toh, Richard B Day, Huaiying Lin, Xiang Gao, Qunfeng Dong, Erica Sodergren Weinstock, George M. Weinstock, Robert S Heyderman, Homer L Twigg, and Stephen B Gordon
HSA: integrating multi-track Hi-C data for genome-scale reconstruction of 3D chromatin structure., Chenchen Zou, Yuping Zhang, and Zhengqing Ouyang
HSF1 critically attunes proteotoxic stress sensing by mTORC1 to combat stress and promote growth., Kuo-Hui Su, Junyue Cao, Zijian Tang, Siyuan Dai, Yishu He, Stephen B. Sampson, Ivor J Benjamin, and Chengkai Dai
HSF1: Guardian of Proteostasis in Cancer., Chengkai Dai and Stephen B. Sampson
Human FcRn Transgenic Mice for Pharmacokinetic Evaluation of Therapeutic Antibodies., Derry C. Roopenian, Gregory J. Christianson, Gabriele Proetzel, and Thomas J. Sproule
Humanized mouse model of mast cell-mediated passive cutaneous anaphylaxis and passive systemic anaphylaxis., Paul J Bryce, Rustom Falahati, Laurie L Kenney, John Leung, Christopher Bebbington, Nenad Tomasevic, Rebecca A Krier, Chia-Lin Hsu, Leonard D Shultz, Dale L Greiner, and Michael A Brehm
Humanized Mouse Models for Transplant Immunology., L L Kenney, Leonard D. Shultz, D L Greiner, and M A Brehm
Hyperactive somatostatin interneurons contribute to excitotoxicity in neurodegenerative disorders., Wen Zhang, Lifeng Zhang, Bo Liang, David Schroeder, Zhong-Wei Zhang, Gregory A. Cox, Yun Li, and Da-Ting Lin
Identification of gene expression in the murine tissue surrounding tumors in patient derived xenograft mouse models., Adam Lavertu
Identification of mutations through dominant screening for obesity using C57BL/6 substrains., Mohammad Sarowar Hossain, Fuyuki Asano, Tomoyuki Fujiyama, Chika Miyoshi, Makito Sato, Aya Ikkyu, Satomi Kanno, Noriko Hotta, Miyo Kakizaki, Takato Honda, Staci J Kim, Haruna Komiya, Ikuo Miura, Tomohiro Suzuki, Kimio Kobayashi, Hideki Kaneda, Vivek Kumar, Joseph S Takahashi, Shigeharu Wakana, Hiromasa Funato, and Masashi Yanagisawa
Identification of quantitative trait loci and candidate genes for an anxiolytic-like response to ethanol in BXD recombinant inbred strains., A H Putman, A R Wolen, J L Harenza, R K Yordanova, B T Webb, Elissa J Chesler, and M F Miles
Identifying genome signatures of drug response in patient derived xenografts (PDX): a machine learning approach., Jacob Luber
IMP3 promotes stem-like properties in triple-negative breast cancer by regulating SLUG., S Samanta, H Sun, H L Goel, B Pursell, C Chang, A Khan, D L Greiner, S Cao, E Lim, Leonard D. Shultz, and A M Mercurio
Improved B cell development in humanized NOD-scid IL2Rγ(null) mice transgenically expressing human stem cell factor, granulocyte-macrophage colony-stimulating factor and interleukin-3., Sonal Jangalwe, Leonard D. Shultz, Anuja Mathew, and Michael A Brehm
Improvements and Limitations of Humanized Mouse Models for HIV Research: NIH/NIAID "Meet the Experts" 2015 Workshop Summary., Ramesh Akkina, Atef Allam, Alejandro B Balazs, Joel N Blankson, John C Burnett, Sofia Casares, J Victor Garcia, Kim J Hasenkrug, Fatah Kashanchi, Scott G Kitchen, Florian Klein, Priti Kumar, Andrew D Luster, Larisa Y Poluektova, Mangala Rao, Brigitte E Sanders-Beer, Leonard D. Shultz, and Jerome A Zack
Induction of WT1-specific human CD8+ T cells from human HSCs in HLA class I Tg NOD/SCID/IL2rgKO mice., Yuho Najima, Mariko Tomizawa-Murasawa, Yoriko Saito, Takashi Watanabe, Rintaro Ono, Toshiki Ochi, Nahoko Suzuki, Hiroshi Fujiwara, Osamu Ohara, Leonard D. Shultz, Masaki Yasukawa, and Fumihiko Ishikawa
Inhibition of the classical pathway of the complement cascade prevents early dendritic and synaptic degeneration in glaucoma., Pete A. Williams, James R Tribble, Keating W. Pepper, Stephen D Cross, B Paul Morgan, James E Morgan, Simon W M John, and Gareth R Howell
Integrative Analysis of PRKAG2 Cardiomyopathy iPS and Microtissue Models Identifies AMPK as a Regulator of Metabolism, Survival, and Fibrosis., J Travis Hinson, Anant Chopra, Andre Lowe, Calvin C Sheng, Rajat M Gupta, Rajarajan Kuppusamy, John O'Sullivan, Glenn Rowe, Hiroko Wakimoto, Joshua Gorham, Kehan Zhang, Kiran Musunuru, Robert E Gerszten, Sean M Wu, Christopher S Chen, Jonathan G Seidman, and Christine E Seidman
Integrative Functional Genomics for Systems Genetics in GeneWeaver.org., Jason A. Bubier, Michael A Langston, Erich J Baker, and Elissa J Chesler
Interleukin 6 Accelerates Mortality by Promoting the Progression of the Systemic Lupus Erythematosus-Like Disease of BXSB.Yaa Mice., Shweta Jain, Giljun Park, Thomas J. Sproule, Gregory J. Christianson, Caroline M. Leeth, Hongsheng Wang, Derry C. Roopenian, and Herbert C Morse
In vitro and in vivo correlates of physiological and neoplastic human Fallopian tube stem cells., Yusuke Yamamoto, Gang Ning, Brooke E Howitt, Karishma Mehra, Lingyan Wu, Xia Wang, Yue Hong, Florian Kern, Tay Seok Wei, Ting Zhang, Niranjan Nagarajan, Debargha Basuli, Suzy Torti, Molly Brewer, Mahesh Choolani, Frank McKeon, Christopher P Crum, and Wa Xian
Isolation of Methicillin-resistant Staphylococcus aureus and Multidrug-resistant Elizabethkingia meningoseptica From Neonates Within Minutes of Birth., Brenda A Kwambana-Adams, Claire S Laxton, Ebenezer Foster-Nyarko, Claire S Laxton, George M. Weinstock, and Martin Antonio
Jonah and his friends at The Jackson Laboratory, Karen Davis and Bob Gottlieb
Kv7 channels in the nucleus accumbens are altered by chronic drinking and are targets for reducing alcohol consumption., Natalie S McGuier, William C Griffin, Justin T Gass, Audrey E Padula, Elissa J Chesler, and Patrick J Mulholland
Lack of Intrinsic GABAergic Connections in the Thalamic Reticular Nucleus of the Mouse., Guoqiang Hou, Alison G Smith, and Zhong-Wei Zhang
Leukaemia cell of origin identified by chromatin landscape of bulk tumour cells., Joshy George, Asli Uyar, Kira Young, Lauren Kuffler, Kaiden Waldron-Francis, Eladio J Marquez, Duygu Ucar, and Jennifer J. Trowbridge
Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α-glucosidase inhibitor or a Nrf2-inducer., Randy Strong, Richard A Miller, Adam Antebi, Clinton M Astle, Molly A. Bogue, Martin S Denzel, Elizabeth Fernandez, Kevin Flurkey, Karyn L Hamilton, Dudley W Lamming, Martin A Javors, João Pedro de Magalhães, Paul Anthony Martinez, Joe M McCord, Benjamin F Miller, Michael Müller, James F Nelson, Juliet Ndukum, G Ed Rainger, Arlan Richardson, David M Sabatini, Adam B Salmon, James W Simpkins, Wilma T Steegenga, Nancy L Nadon, and David E Harrison
Longitudinal Prediction of the Infant Gut Microbiome with Dynamic Bayesian Networks., Michael J McGeachie, Joanne E Sordillo, Travis Gibson, George M. Weinstock, Yang-Yu Liu, Diane R Gold, Scott T Weiss, and Augusto Litonjua
Long-term clinical follow-up and molecular testing for diagnosis of the first Tunisian family with Alström syndrome., Amine Chakroun, Mariem Ben Said, Amine Ennouri, Imen Achour, Mouna Mnif, Mohamed Abid, Abdelmonem Ghorbel, Jan D. Marshall, Juergen K. Naggert, and Saber Masmoudi
Loss-of-function mutations in the C9ORF72 mouse ortholog cause fatal autoimmune disease., Aaron Burberry, Naoki Suzuki, Jin-Yuan Wang, Rob Moccia, Daniel A Mordes, Morag H Stewart, Satomi Suzuki-Uematsu, Sulagna Ghosh, Ajay Singh, Florian T Merkle, Kathryn Koszka, Quan-Zhen Li, Leonard Zon, Derrick J Rossi, Jennifer J. Trowbridge, Luigi D Notarangelo, and Kevin Eggan
Loss of Kynurenine 3-Mono-oxygenase Causes Proteinuria., Ron Korstanje, Konstantin Deutsch, Patricia Bolanos-Palmieri, Nils Hanke, Patricia Schroder, Lynne Staggs, Jan H Bräsen, Ian S D Roberts, Susan Sheehan, Holly S Savage, Hermann Haller, and Mario Schiffer
Lung microbiome in human immunodeficiency virus infection., Homer L Twigg, George M. Weinstock, and Kenneth S Knox
Maternal IL-6 can cause T-cell-mediated juvenile alopecia by non-scarring follicular dystrophy in mice., Stephen E P Smith, Rachel L G Maus, Tessa R Davis, John P Sundberg, Diana Gil, and Adam G Schrum
Meox2 haploinsufficiency increases neuronal cell loss in a mouse model of Alzheimer's disease., Ileana Soto, Weronika Grabowska, Kristen D. Onos, Leah C. Graham, Harriet M. Jackson, Stephen N. Simeone, and Gareth R Howell
Metabolic control of the proteotoxic stress response: implications in diabetes mellitus and neurodegenerative disorders., Kuo-Hui Su and Chengkai Dai
Metabolite profile of a mouse model of Charcot-Marie-Tooth type 2D neuropathy: implications for disease mechanisms and interventions., Preeti Bais, Kirk Beebe, Kathryn H. Morelli, Meagan E Currie, Sara N Norberg, Alexei V Evsikov, Kathy E Miers, Kevin L. Seburn, Velina Guergueltcheva, Ivo Kremensky, Albena Jordanova, Carol J Bult, and Robert W. Burgess
Metagenomic Approach for Identification of the Pathogens Associated with Diarrhea in Stool Specimens., Yanjiao Zhou, Kristine M Wylie, Rana E El Feghaly, Kathie A Mihindukulasuriya, Alexis Elward, David B Haslam, Gregory A Storch, and George M. Weinstock
Methodological Considerations for Optimizing and Validating Behavioral Assays., Stacey J Sukoff Rizzo and Jill L Silverman
Mining biomedical images towards valuable information retrieval in biomedical and life sciences., Zeeshan Ahmed, Saman Zeeshan, and Thomas Dandekar
MmuPV1 infection and tumor development of T cell-deficient mice is prevented by passively transferred hyperimmune sera from normal congenic mice immunized with MmuPV1 virus-like particles (VLPs)., Joongho Joh, Shin-Je Ghim, Paula M Chilton, John P Sundberg, Jino Park, Sarah A Wilcher, Mary L Proctor, and A Bennett Jenson
Modeling biochemical pathways in the gene ontology., David P. Hill, Peter D'Eustachio, Tanya Z Berardini, Christopher J Mungall, Nikolai Renedo, and Judith A. Blake
Modulation of unloading-induced bone loss in mice with altered ERK signaling., Jeyantt S Sankaran, Bing Li, Leah Rae Donahue, and Stefan Judex
Molecular Genetic Analysis of Ovarian Brenner Tumors and Associated Mucinous Epithelial Neoplasms: High Variant Concordance and Identification of Mutually Exclusive RAS Driver Mutations and MYC Amplification., Laura J Tafe, Kristen E Muller, Guruprasad Ananda, Talia Mitchell, Vanessa Spotlow, Sara E. Patterson, Gregory J Tsongalis, and Susan Mockus
Mouse genome database 2016., Carol J Bult, Janan T. Eppig, Judith A. Blake, James A. Kadin, and Joel E Richardson
Mouse Genome Informatics (MGI): Resources for Mining Mouse Genetic, Genomic, and Biological Data in Support of Primary and Translational Research., Janan T. Eppig, Cynthia Smith, Judith A. Blake, Martin Ringwald, James A. Kadin, Joel E Richardson, and Carol J Bult
Mouse genome-wide association study identifies polymorphisms on chromosomes 4, 11, and 15 for age-related cardiac fibrosis., Qiaoli Li, Annerose Berndt, Beth A. Sundberg, Kathleen A Silva, Victoria E. Kennedy, Clinton L Cario, Matthew A Richardson, Thomas H Chase, Paul N Schofield, Jouni Uitto, and John P Sundberg
Mouse Models of NMNAT1-Leber Congenital Amaurosis (LCA9) Recapitulate Key Features of the Human Disease., Scott H Greenwald, Jeremy R. Charette, Magdalena Staniszewska, Lan Ying Shi, Steve D M Brown, Lisa Stone, Qin Liu, Wanda L. Hicks, Gayle B. Collin, Michael R Bowl, Mark P. Krebs, Patsy M. Nishina, and Eric A Pierce
Mouse Sperm Cryopreservation and Recovery of Genetically Modified Mice., Benjamin E. Low, Robert A. Taft, and Michael V. Wiles
multiClust: An R-package for Identifying Biologically Relevant Clusters in Cancer Transcriptome Profiles, Nathan Lawlor, Alec Fabbri, Peiyong Guan, Joshy George, and Radha Krishna Murthy Karuturi
Mutations in CTNNA1 cause butterfly-shaped pigment dystrophy and perturbed retinal pigment epithelium integrity., Nicole T M Saksens, Mark P. Krebs, Frederieke E Schoenmaker-Koller, Wanda L. Hicks, Minzhong Yu, Lanying Shi, Lucy B. Rowe, Gayle B. Collin, Jeremy R. Charette, Stef J Letteboer, Kornelia Neveling, Tamara W van Moorsel, Sleiman Abu-Ltaif, Elfride De Baere, Sophie Walraedt, Sandro Banfi, Francesca Simonelli, Frans P M Cremers, Camiel J F Boon, Ronald Roepman, Bart P Leroy, Neal S Peachey, Carel B Hoyng, Patsy M. Nishina, and Anneke I den Hollander
Mutations in SMG9, Encoding an Essential Component of Nonsense-Mediated Decay Machinery, Cause a Multiple Congenital Anomaly Syndrome in Humans and Mice., Ranad Shaheen, Shams Anazi, Tawfeg Ben-Omran, Mohammed Zain Seidahmed, L Brianna Caddle, Kristina Palmer, Rehab Ali, Tarfa Alshidi, Samya Hagos, Leslie Goodwin, Mais Hashem, Salma M Wakil, Mohamed Abouelhoda, Dilek Colak, Stephen A. Murray, and Fowzan S Alkuraya
N-acetyl-cysteine prevents age-related hearing loss and the progressive loss of inner hair cells in γ-glutamyl transferase 1 deficient mice., Dalian Ding, Haiyan Jiang, Guang-Di Chen, Chantal M. Longo-Guess, Vijaya Prakash Krishnan Muthaiah, Cong Tian, Adam Sheppard, Richard Salvi, and Kenneth R. Johnson
Nature and nurture: a modern synthesis., John L. Fuller
Neuroinflammation and early cognitive decline induced by short-term exposure to western diet in C57BL/6J mice., Weronika Grabowska
Neuromuscular Disease Models and Analysis., Robert W. Burgess, Gregory A. Cox, and Kevin L. Seburn
Neuroprotective drug treatment in DBA/2J glaucoma., Kelly Cochran
NIH working group report-using genomic information to guide weight management: From universal to precision treatment., Molly S Bray, Ruth J F Loos, Jeanne M McCaffery, Charlotte Ling, Paul W Franks, George M. Weinstock, Michael P Snyder, Jason L Vassy, and Tanya Agurs-Collins
Nonproliferative and Proliferative Lesions of the Gastrointestinal Tract, Pancreas and Salivary Glands of the Rat and Mouse., Thomas Nolte, Patricia Brander-Weber, Charles Dangler, Ulrich Deschl, Michael R Elwell, Peter Greaves, Richard Hailey, Michael W Leach, Arun R Pandiri, Arlin Rogers, Cynthia C Shackelford, Andrew Spencer, Takuji Tanaka, and Jerrold M Ward
Novel axon projection after stress and degeneration in the Dscam mutant retina., K A Fernandes, S J Bloomsburg, C J Miller, S A Billingslea, M M Merrill, Robert W. Burgess, R T Libby, and P G Fuerst
Novel theranostic nanoporphyrins for photodynamic diagnosis and trimodal therapy for bladder cancer., Tzu-Yin Lin, Yuanpei Li, Qiangqiang Liu, Jui-Lin Chen, Hongyong Zhang, Diana Lac, Hua Zhang, Katherine W Ferrara, Sebastian Wachsmann-Hogiu, Tianhong Li, Susan Airhart, Ralph deVere White, Kit S Lam, and Chong-Xian Pan
OmniSearch: a semantic search system based on the Ontology for MIcroRNA Target (OMIT) for microRNA-target gene interaction data., Jingshan Huang, Fernando Gutierrez, Harrison J Strachan, Dejing Dou, Weili Huang, Barry Smith, Judith A. Blake, Karen Eilbeck, Darren A Natale, Yu Lin, Bin Wu, Nisansa de Silva, Xiaowei Wang, Zixing Liu, Glen M Borchert, Ming Tan, and Alan Ruttenberg
Onco-Hu™ Models: Humanized NSG™ and NSG™-SGM3 Mice for Immuno-Oncology, JAX Mice, Clinical and Research Services
Oocyte-dependent activation of MTOR in cumulus cells controls the development and survival of cumulus-oocyte complexes., Jing Guo, Lanying Shi, Xuhong Gong, Mengjie Jiang, Yaoxue Yin, Xiaoyun Zhang, Hong Yin, Hui Li, Chihiro Emori, Koji Sugiura, John J. Eppig, and You-Qiang Su
Organization, evolution and functions of the human and mouse Ly6/uPAR family genes., Chelsea L Loughner, Elspeth A Bruford, Monica McAndrews, Emili E Delp, Sudha Swamynathan, and Shivalingappa K Swamynathan
Orthologs and isoforms and conservation of function., Daniela Perry
Ovariectomy results in inbred strain-specific increases in anxiety-like behavior in mice., Sarah Adams Schoenrock, Daniel Oreper, Nancy Young, Robin Betsch Ervin, Molly A. Bogue, William Valdar, and Lisa M Tarantino
Oxidized mitochondrial nucleoids released by neutrophils drive type I interferon production in human lupus., Simone Caielli, Shruti Athale, Bojana Domic, Elise Murat, Manjari Chandra, Romain Banchereau, Jeanine Baisch, Kate Phelps, Sandra Clayton, Mei Gong, Tracey Wright, Marilynn Punaro, Karolina Palucka, Cristiana Guiducci, Jacques Banchereau, and Virginia Pascual
Patient-Derived Tumor Xenografts: Why Now?, Edison T. Liu, Carol J Bult, and Leonard D. Shultz
Penetrance of Congenital Heart Disease in a Mouse Model of Down Syndrome Depends on a Trisomic Potentiator of a Disomic Modifier., Huiqing Li, Sarah Edie, Donna Klinedinst, Jun Seop Jeong, Seth Blackshaw, Cheryl L Maslen, and Roger H Reeves
Personalized Immunomonitoring Uncovers Molecular Networks that Stratify Lupus Patients., Romain Banchereau, Seunghee Hong, Brandi Cantarel, Nicole Baldwin, Jeanine Baisch, Michelle Edens, Alma-Martina Cepika, Peter Acs, Jacob Turner, Esperanza Anguiano, Parvathi Vinod, Shaheen Kahn, Gerlinde Obermoser, Derek Blankenship, Edward Wakeland, Lorien Nassi, Alisa Gotte, Marilynn Punaro, Yong-Jun Liu, Jacques Banchereau, Jose Rossello-Urgell, Tracey Wright, and Virginia Pascual
Pituitary morphovolumetric changes in Alström syndrome., Valentina Citton, Pietro Maffei, Jan D. Marshall, Alessandro Baglione, Gayle B. Collin, Gabriella Milan, Roberto Vettor, Juergen K. Naggert, and Renzo Manara
P-Rex1 Promotes Resistance to VEGF/VEGFR-Targeted Therapy in Prostate Cancer., Hira Lal Goel, Bryan Pursell, Leonard D. Shultz, Dale L Greiner, Rolf A Brekken, Craig W Vander Kooi, and Arthur M Mercurio
Progressive alterations in multipotent hematopoietic progenitors underlie lymphoid cell loss in aging., Kira Young, Sneha Borikar, Rebecca Bell, Lauren Kuffler, Vivek M. Philip, and Jennifer J. Trowbridge
Protein quantity-quality balance licenses growth., Kuo-Hui Su and Chengkai Dai
Punctuated bursts in human male demography inferred from 1,244 worldwide Y-chromosome sequences., G David Poznik, Yali Xue, Fernando L Mendez, Thomas F Willems, Andrea Massaia, Melissa A Wilson Sayres, Qasim Ayub, Shane A McCarthy, Apurva Narechania, Seva Kashin, Yuan Chen, Ruby Banerjee, Juan L Rodriguez-Flores, Maria Cerezo, Haojing Shao, Melissa Gymrek, Ankit Malhotra, Sandra Louzada, Rob Desalle, Graham R S Ritchie, Eliza Cerveira, Tomas W Fitzgerald, Erik Garrison, Anthony Marcketta, David Mittelman, Mallory Romanovitch, Chengsheng Zhang, Xiangqun Zheng-Bradley, Gonçalo R Abecasis, Steven A McCarroll, Paul Flicek, Peter A Underhill, Lachlan Coin, Daniel R Zerbino, Fengtang Yang, Charles Lee, Laura Clarke, Adam Auton, Yaniv Erlich, Robert E Handsaker, Carlos D Bustamante, and Chris Tyler-Smith
QTL Mapping and Identification of Candidate Genes in DO Mice: A Use Case Model Derived from a Benzene Toxicity Experiment., Daniel Mario Gatti, John E French, and Klaus Schughart
QuIN: A Web Server for Querying and Visualizing Chromatin Interaction Networks., Asa Thibodeau, Eladio J Márquez, Oscar Junhong Luo, Yijun Ruan, Francesca Menghi, Dong-Guk Shin, Michael L. Stitzel, Paola Vera-Licona, and Duygu Ucar
R2d2 drives selfish sweeps in the house mouse., John P Didion, Andrew P Morgan, Liran Yadgary, Timothy A Bell, Rachel C McMullan, Lydia Ortiz de Solorzano, Janice Britton-Davidian, Carol J Bult, Karl J Campbell, Riccardo Castiglia, Yung-Hao Ching, Amanda J Chunco, James J Crowley, Elissa J Chesler, Daniel W Förster, John E French, Sofia I Gabriel, Daniel Mario Gatti, Theodore Garland, Eva B Giagia-Athanasopoulou, Mabel D Giménez, Sofia A Grize, Islam Gündüz, Andrew Holmes, Heidi C Hauffe, Jeremy S Herman, James M Holt, Kunjie Hua, Wesley J Jolley, Anna K Lindholm, María J López-Fuster, George Mitsainas, Maria da Luz Mathias, Leonard McMillan, M Graça Ramalhinho, Barbara Rehermann, Stephan P Rosshart, Jeremy B Searle, Meng-Shin Shiao, Emanuela Solano, Karen L Svenson, Pat Thomas-Laemont, David W Threadgill, Jacint Ventura, George M. Weinstock, Daniel Pomp, Gary Churchill, and Fernando Pardo-Manuel de Villena
Rapamycin treatment benefits glucose metabolism in mouse models of type 2 diabetes., Peter C. Reifsnyder, Kevin Flurkey, Austen Te, and David E Harrison
Reduced in vivo hepatic proteome replacement rates but not cell proliferation rates predict maximum lifespan extension in mice., Airlia C S Thompson, Matthew D Bruss, John C Price, Cyrus F Khambatta, William E Holmes, Marc Colangelo, Marcy Dalidd, Lindsay S Roberts, Clinton M Astle, David E Harrison, and Marc K Hellerstein
Reducing translation through eIF4G/IFG-1 improves survival under ER stress that depends on heat shock factor HSF-1 in Caenorhabditis elegans., Amber C Howard, Jarod Rollins, Santina Snow, Sarah Castor, and Aric N Rogers
Reference Guide to Mouse Models of Spinal Muscular Atrophy, Melissa Osborne and Cathleen Lutz
Refined mapping of autoimmune disease associated genetic variants with gene expression suggests an important role for non-coding RNAs., Isis Ricaño-Ponce, Daria V Zhernakova, Patrick Deelen, Oscar Junhong Luo, Xingwang Li, Aaron Isaacs, Juha Karjalainen, Jennifer Di Tommaso, Zuzanna Agnieszka Borek, Maria M Zorro, Javier Gutierrez-Achury, Andre G Uitterlinden, Albert Hofman, Joyce van Meurs, Mihai G Netea, Iris H Jonkers, Sebo Withoff, Cornelia M van Duijn, Yang Li, Yijun Ruan, Lude Franke, Cisca Wijmenga, and Vinod Kumar
Regenerative medicine: today's discoveries informing the future of medical practice., Nadia Rosenthal and Stephen Badylak
Regulatory complexity revealed by integrated cytological and RNA-seq analyses of meiotic substages in mouse spermatocytes., Robyn L Ball, Yasuhiro Fujiwara, Fengyun Sun, Jianjun Hu, Matthew A Hibbs, Mary Ann Handel, and Gregory W. Carter
Repetitive Behavioral Assessments for Compound Screening in Mouse Models of Autism Spectrum Disorders., S J Sukoff Rizzo
Replacing the PDZ-interacting C-termini of DSCAM and DSCAML1 with epitope tags causes different phenotypic severity in different cell populations., Andrew M. Garrett, Abby Tadenev, Yuna T Hammond, Peter G Fuerst, and Robert W. Burgess
Reply to Watkins et al.: Whole-genome sequencing-based identification of diverse tandem duplicator phenotypes in human cancers., Francesca Menghi and Edison Liu
Retinal Pigment Epithelium Atrophy 1 (rpea1): A New Mouse Model With Retinal Detachment Caused by a Disruption of Protein Kinase C, θ., Xiaojie Ji, Ye Liu, Ronald E. Hurd, Jieping Wang, Bernie Fitzmaurice, Patsy M. Nishina, and Bo Chang
Retrospective Evaluation of Nail Trimming as a Conservative Treatment for Ulcerative Dermatitis in Laboratory Mice., Cynthia G Alvarado, Craig L Franklin, and Lonny W Dixon
Revisiting Cardiac Cellular Composition., Alexander R Pinto, Alexei Ilinykh, Malina J Ivey, Jill T Kuwabara, Michelle L D'Antoni, Ryan Debuque, Anjana Chandran, Lina Wang, Komal Arora, Nadia A Rosenthal, and Michelle D Tallquist
Role of Clinicogenomics in Infectious Disease Diagnostics and Public Health Microbiology., Lars F Westblade, Alex van Belkum, Adam Grundhoff, George M. Weinstock, Eric G Pamer, Mark J Pallen, and W Michael Dunne
Searching the Mouse Genome Informatics (MGI) Resources for Information on Mouse Biology from Genotype to Phenotype., David R. Shaw
Selective ORAI1 Inhibition Ameliorates Autoimmune Central Nervous System Inflammation by Suppressing Effector but Not Regulatory T Cell Function., Ulrike Kaufmann, Patrick J Shaw, Lina Kozhaya, Raju Subramanian, Kevin Gaida, Derya Unutmaz, Helen J McBride, and Stefan Feske
Show and tell: disclosure and data sharing in experimental pathology., Paul N. Schofield, Jerrold M. Ward, and John P Sundberg
Simple, Efficient CRISPR-Cas9-Mediated Gene Editing in Mice: Strategies and Methods., Benjamin E. Low, Peter M Kutny, and Michael V. Wiles
Single amino acid deletion in transmembrane segment D4S6 of sodium channel Scn8a (Nav1.6) in a mouse mutant with a chronic movement disorder., Julie M Jones, Louise A. Dionne, James Dell'Orco, Rachel Parent, Jamie N Krueger, Xiaoyang Cheng, Sulayman D Dib-Hajj, Rosie K Bunton-Stasyshyn, Lisa M Sharkey, James J Dowling, Geoffrey G Murphy, Vikram G Shakkottai, Peter Shrager, and Miriam H Meisler
Single-cell multimodal profiling reveals cellular epigenetic heterogeneity., Lih Feng Cheow, Elise T Courtois, Yuliana Tan, Ramya Viswanathan, Qiaorui Xing, Rui Zhen Tan, Daniel S W Tan, Paul Robson, Yuin-Han Loh, Stephen R Quake, and William F Burkholder
Skin Diseases in Laboratory Mice: Approaches to Drug Target Identification and Efficacy Screening., John P Sundberg, Kathleen A Silva, Lloyd E King, and C Herbert Pratt
Somatic gene mutation analysis of triple negative breast cancers., J L Dillon, Susan Mockus, Guruprasad Ananda, Vanessa Spotlow, W A Wells, Gregory J Tsongalis, and J D Marotti
Splicing-factor alterations in cancers., Olga Anczuków and Adrian R Krainer
Spontaneous 8bp Deletion in Nbeal2 Recapitulates the Gray Platelet Syndrome in Mice., Kärt Tomberg, Rami Khoriaty, Randal J Westrick, Heather Fairfield, Laura G Reinholdt, Gary L Brodsky, Pavel Davizon-Castillo, David Ginsburg, and Jorge Di Paola
Spontaneous partial loss of the OT-I transgene., Gretchen Harms Pritchard, Eric W Cross, Marjorie Strobel, Stephen C Jameson, Ross M Kedl, Kristin A Hogquist, and Christopher A Hunter
Store-Operated Ca(2+) Entry in Follicular T Cells Controls Humoral Immune Responses and Autoimmunity., Martin Vaeth, Miriam Eckstein, Patrick J Shaw, Lina Kozhaya, Jun Yang, Friederike Berberich-Siebelt, Robert Clancy, Derya Unutmaz, and Stefan Feske
Stress-impaired transcription factor expression and insulin secretion in transplanted human islets., Chunhua Dai, Nora S Kayton, Alena Shostak, Greg Poffenberger, Holly A Cyphert, Radhika Aramandla, Courtney Thompson, Ioannis G Papagiannis, Christopher Emfinger, Masakazu Shiota, John M Stafford, Dale L Greiner, Pedro L Herrera, Leonard D. Shultz, Roland Stein, and Alvin C Powers
Sudden acquired retinal degeneration syndrome (SARDS) - a review and proposed strategies toward a better understanding of pathogenesis, early diagnosis, and therapy., András M Komáromy, Kenneth L Abrams, John R Heckenlively, Steven K Lundy, David J Maggs, Caroline M Leeth, Puliyur S MohanKumar, Simon M Petersen-Jones, David V. Serreze, and Alexandra van der Woerdt
Superimposing gene expression data onto gene interaction data to evaluate molecular networks during mouse development., Dylan Maghini
Symbiotic Burkholderia Species Show Diverse Arrangements of nif/fix and nod Genes and Lack Typical High-Affinity Cytochrome cbb3 Oxidase Genes., Sofie E De Meyer, Leah Briscoe, Pilar Martínez-Hidalgo, Christina M Agapakis, Paulina Estrada de-Los Santos, Rekha Seshadri, Wayne Reeve, George M. Weinstock, Graham O'Hara, John G Howieson, and Ann M Hirsch
Synaptic Deficits at Neuromuscular Junctions in Two Mouse Models of Charcot-Marie-Tooth Type 2d., Emily L Spaulding, James N Sleigh, Kathryn H. Morelli, Martin J Pinter, Robert W. Burgess, and Kevin L. Seburn
Systems genetic and pharmacological analysis identifies candidate genes underlying mechanosensation in the von Frey test., E E Young, C D Bryant, S E Lee, X Peng, B Cook, H K Nair, K J Dreher, X Zhang, A A Palmer, J M Chung, J S Mogil, Elissa J Chesler, and W R Lariviere
Systems genetics of intravenous cocaine self-administration in the BXD recombinant inbred mouse panel., Price E. Dickson, Mellessa M Miller, Michele A Calton, Jason A. Bubier, Melloni N Cook, Daniel Goldowitz, Elissa J. Chesler, and Guy Mittleman
Taking a BAT at obesity with Ucp1., Judy A. Yau
Targeted therapeutic treatment of MLL-rearranged AML based on the cell of origin., Matthew A. Loberg
Targeting dendritic cells in humanized mice receiving adoptive T cells via monoclonal antibodies fused to Flu epitopes., John P Graham, Pierre Authie, Chun I. Yu, Sandra M Zurawski, Xiao-Hua Li, Florentina Marches, Anne-Laure Flamar, Aditi Acharya, Jacques Banchereau, and A Karolina Palucka
TauCstF-64 Mediates Correct mRNA Polyadenylation and Splicing of Activator and Repressor Isoforms of the Cyclic AMP-Responsive Element Modulator (CREM) in Mouse Testis., Petar N Grozdanov, Atia Amatullah, Joel H. Graber, and Clinton C MacDonald
Temporal dynamics of the developing lung transcriptome in three common inbred strains of laboratory mice reveals multiple stages of postnatal alveolar development., Kyle J Beauchemin, Julie M Wells, Alvin T Kho, Vivek M. Philip, Daniela Kamir, Isaac S Kohane, Joel H. Graber, and Carol J Bult
Temporal Stability of the Human Skin Microbiome., Julia Oh, Allyson L Byrd, Morgan Park, NISC Compartive Sequencing Program, Heidi H Kong, and Julia A Segre
Testing the Feasibility of Remote Patient Monitoring in Prenatal Care Using a Mobile App and Connected Devices: A Prospective Observational Trial., Kathryn I Marko, Jill M Krapf, Andrew C Meltzer, Julia Oh, Nihar Ganju, Anjali G Martinez, Sheetal G Sheth, and Nancy D Gaba
The Actin-Binding Protein α-Adducin Is Required for Maintaining Axon Diameter., Sérgio Carvalho Leite, Paula Sampaio, Vera Filipe Sousa, Joana Nogueira-Rodrigues, Rita Pinto-Costa, Luanne L. Peters, Pedro Brites, and Mónica Mendes Sousa
The Basis of Oncoimmunology., A. Karolina Palucka and Lisa M Coussens
The biological significance of hub genes found by weighted correlation network analysis., Reanna Dona
The cardiac fibroblast: Origin, identity and role in homeostasis and disease., Milena B Furtado, Mauro W Costa, and Nadia Rosenthal
The Cell Ontology 2016: enhanced content, modularization, and ontology interoperability., Alexander D Diehl, Terrence F Meehan, Yvonne M Bradford, Matthew H Brush, Wasila M Dahdul, David S Dougall, Yongqun He, David Osumi-Sutherland, Alan Ruttenberg, Sirarat Sarntivijai, Ceri E Van Slyke, Nicole A Vasilevsky, Melissa A Haendel, Judith A. Blake, and Christopher J Mungall
The challenges of mosaicism., Emily Keator
The clinical trial landscape in oncology and connectivity of somatic mutational profiles to targeted therapies., Sara E. Patterson, Rangjiao Liu, Cara M. Statz, Daniel Durkin, Anuradha Lakshminarayana, and Susan M. Mockus
The development of non-coding RNA ontology., Jingshan Huang, Karen Eilbeck, Barry Smith, Judith A. Blake, Dejing Dou, Weili Huang, Darren A Natale, Alan Ruttenberg, Jun Huan, Michael T Zimmermann, Guoqian Jiang, Yu Lin, Bin Wu, Harrison J Strachan, Nisansa de Silva, Mohan Vamsi Kasukurthi, Vikash Kumar Jha, Yongqun He, Shaojie Zhang, Xiaowei Wang, Zixing Liu, Glen M Borchert, and Ming Tan
The effectiveness of CHK2 inhibitors for oocyte survival after induced DNA damage., Julia Loose
The effect of repurposed drugs: sertraline, fluoxetine, and cannibidiol on spontaneous seizure activity in fitful mice., Jacqueline Bridges
The genetic architecture of type 2 diabetes., Christian Fuchsberger, Jason Flannick, Tanya M Teslovich, Anubha Mahajan, Vineeta Agarwala, Kyle J Gaulton, Clement Ma, Pierre Fontanillas, Loukas Moutsianas, Davis J McCarthy, Manuel A Rivas, John R B Perry, Xueling Sim, Thomas W Blackwell, Neil R Robertson, N William Rayner, Pablo Cingolani, Adam E Locke, Juan Fernandez Tajes, Heather M Highland, Josee Dupuis, Peter S Chines, Cecilia M Lindgren, Christopher Hartl, Anne U Jackson, Han Chen, Jeroen R Huyghe, Martijn van de Bunt, Richard D Pearson, Ashish Kumar, Martina Müller-Nurasyid, Niels Grarup, Heather M Stringham, Eric R Gamazon, Jaehoon Lee, Yuhui Chen, Robert A Scott, Jennifer E Below, Peng Chen, Jinyan Huang, Min Jin Go, Michael L. Stitzel, Dorota Pasko, Stephen C J Parker, Tibor V Varga, Todd Green, Nicola L Beer, Aaron G Day-Williams, Teresa Ferreira, Tasha Fingerlin, Momoko Horikoshi, Cheng Hu, Iksoo Huh, Mohammad Kamran Ikram, Bong-Jo Kim, Yongkang Kim, Young Jin Kim, Min-Seok Kwon, Juyoung Lee, Selyeong Lee, Keng-Han Lin, Taylor J Maxwell, Yoshihiko Nagai, Xu Wang, Ryan P Welch, Joon Yoon, Weihua Zhang, Nir Barzilai, Benjamin F Voight, Bok-Ghee Han, Christopher P Jenkinson, Teemu Kuulasmaa, Johanna Kuusisto, Alisa Manning, Maggie C Y Ng, Nicholette D Palmer, Beverley Balkau, Alena Stancáková, Hanna E Abboud, Heiner Boeing, Vilmantas Giedraitis, Dorairaj Prabhakaran, Omri Gottesman, James Scott, Jason Carey, Phoenix Kwan, George Grant, Joshua D Smith, Benjamin M Neale, Shaun Purcell, Adam S Butterworth, Joanna M M Howson, Heung Man Lee, Yingchang Lu, Soo-Heon Kwak, Wei Zhao, John Danesh, Vincent K L Lam, Kyong Soo Park, Danish Saleheen, Wing Yee So, Claudia H T Tam, Uzma Afzal, David Aguilar, Rector Arya, Tin Aung, Edmund Chan, Carmen Navarro, Ching-Yu Cheng, Domenico Palli, Adolfo Correa, Joanne E Curran, Denis Rybin, Vidya S Farook, Sharon P Fowler, Barry I Freedman, Michael Griswold, Daniel Esten Hale, Pamela J Hicks, Chiea-Chuen Khor, Satish Kumar, Benjamin Lehne, Dorothée Thuillier, Wei Yen Lim, Jianjun Liu, Yvonne T van der Schouw, Marie Loh, Solomon K Musani, Sobha Puppala, William R Scott, Loïc Yengo, Sian-Tsung Tan, Herman A Taylor, Farook Thameem, Gregory Wilson, Tien Yin Wong, Pål Rasmus Njølstad, Jonathan C Levy, Massimo Mangino, Lori L Bonnycastle, Thomas Schwarzmayr, João Fadista, Gabriela L Surdulescu, Christian Herder, Christopher J Groves, Thomas Wieland, Jette Bork-Jensen, Ivan Brandslund, Cramer Christensen, Heikki A Koistinen, Alex S F Doney, Leena Kinnunen, Tõnu Esko, Andrew J Farmer, Liisa Hakaste, Dylan Hodgkiss, Jasmina Kravic, Valeriya Lyssenko, Mette Hollensted, Marit E Jørgensen, Torben Jørgensen, Claes Ladenvall, Johanne Marie Justesen, Annemari Käräjämäki, Jennifer Kriebel, Wolfgang Rathmann, Lars Lannfelt, Torsten Lauritzen, Narisu Narisu, Allan Linneberg, Olle Melander, Lili Milani, Matt Neville, Marju Orho-Melander, Lu Qi, Qibin Qi, Michael Roden, Olov Rolandsson, Amy Swift, Anders H Rosengren, Kathleen Stirrups, Andrew R Wood, Evelin Mihailov, Christine Blancher, Mauricio O Carneiro, Jared Maguire, Ryan Poplin, Khalid Shakir, Timothy Fennell, Mark DePristo, Martin Hrabé de Angelis, Panos Deloukas, Anette P Gjesing, Goo Jun, Peter Nilsson, Jacquelyn Murphy, Robert Onofrio, Barbara Thorand, Torben Hansen, Christa Meisinger, Frank B Hu, Bo Isomaa, Fredrik Karpe, Liming Liang, Annette Peters, Cornelia Huth, Stephen P O'Rahilly, Colin N A Palmer, Oluf Pedersen, Rainer Rauramaa, Jaakko Tuomilehto, Veikko Salomaa, Richard M Watanabe, Ann-Christine Syvänen, Richard N Bergman, Dwaipayan Bharadwaj, Erwin P Bottinger, Yoon Shin Cho, Giriraj R Chandak, Juliana C N Chan, Kee Seng Chia, Mark J Daly, Shah B Ebrahim, Claudia Langenberg, Paul Elliott, Kathleen A Jablonski, Donna M Lehman, Weiping Jia, Ronald C W Ma, Toni I Pollin, Manjinder Sandhu, Nikhil Tandon, Philippe Froguel, Inês Barroso, Yik Ying Teo, Eleftheria Zeggini, Ruth J F Loos, Kerrin S Small, Janina S Ried, Ralph A DeFronzo, Harald Grallert, Benjamin Glaser, Andres Metspalu, Nicholas J Wareham, Mark Walker, Eric Banks, Christian Gieger, Erik Ingelsson, Hae Kyung Im, Thomas Illig, Paul W Franks, Gemma Buck, Joseph Trakalo, David Buck, Inga Prokopenko, Reedik Mägi, Lars Lind, Yossi Farjoun, Katharine R Owen, Anna L Gloyn, Konstantin Strauch, Tiinamaija Tuomi, Jaspal Singh Kooner, Jong-Young Lee, Taesung Park, Peter Donnelly, Andrew D Morris, Andrew T Hattersley, Donald W Bowden, Francis S Collins, Gil Atzmon, John C Chambers, Timothy D Spector, Markku Laakso, Tim M Strom, Graeme I Bell, John Blangero, Ravindranath Duggirala, E Shyong Tai, Gilean McVean, Craig L Hanis, James G Wilson, Mark Seielstad, Timothy M Frayling, James B Meigs, Nancy J Cox, Rob Sladek, Eric S Lander, Stacey Gabriel, Noël P Burtt, Karen L Mohlke, Thomas Meitinger, Leif Groop, Goncalo Abecasis, Jose C Florez, Laura J Scott, Andrew P Morris, Hyun Min Kang, Michael Boehnke, David Altshuler, and Mark I McCarthy
The Genetic Basis of Baculum Size and Shape Variation in Mice., Nicholas G Schultz, Jesse Ingels, Andrew Hillhouse, Keegan Wardwell, Peter L Chang, James M Cheverud, Cathleen Lutz, Lu Lu, Robert W Williams, and Matthew D Dean
The Human Vaccines Project: A roadmap for cancer vaccine development., Pedro Romero, Jacques Banchereau, Nina Bhardwaj, Mark Cockett, Mary L Disis, Glenn Dranoff, Eli Gilboa, Scott A Hammond, Robert Hershberg, Alan J Korman, Pia Kvistborg, Cornelis Melief, Ira Mellman, Karolina Palucka, Irina Redchenko, Harlan Robins, Federica Sallusto, Theodore Schenkelberg, Stephen Schoenberger, Jeffrey Sosman, Özlem Türeci, Benoît Van den Eynde, Wayne Koff, and George Coukos
The importance of the microbiome in epidemiologic research., Blake M Hanson and George M. Weinstock
The influence of the NOD/ShiLtJ genetic background on a mouse model of Alzheimer's disease., Calvin Coffey
The long non-coding RNA Morrbid regulates Bim and short-lived myeloid cell lifespan., Jonathan J Kotzin, Sean P Spencer, Sam J McCright, Dinesh B Uthaya Kumar, Magalie A Collet, Walter K Mowel, Ellen N Elliott, Asli Uyar, Michelle A Makiya, Margaret C Dunagin, Christian C D Harman, Anthony T Virtue, Stella Zhu, Will Bailis, Judith Stein, Cynthia Hughes, Arjun Raj, E John Wherry, Loyal A Goff, Amy D Klion, John L Rinn, Adam Williams, Richard A Flavell, and Jorge Henao-Mejia
The Mediator of Hematopoietic Stem Cell Homeostasis., Sneha Borikar and Jennifer J. Trowbridge
The Meiotic Recombination Activator PRDM9 Trimethylates Both H3K36 and H3K4 at Recombination Hotspots In Vivo., Natalie R Powers, Emil D Parvanov, Christopher L. Baker, Michael Walker, Petko M. Petkov, and Kenneth Paigen
The Mouse Universal Genotyping Array: From Substrains to Subspecies., Andrew P Morgan, Chen-Ping Fu, Chia-Yu Kao, Catherine E Welsh, John P Didion, Liran Yadgary, Leeanna Hyacinth, Martin T Ferris, Timothy A Bell, Darla R Miller, Paola Giusti-Rodriguez, Randal J Nonneman, Kevin D Cook, Jason K Whitmire, Lisa E Gralinski, Mark Keller, Alan D Attie, Gary Churchill, Petko M. Petkov, Patrick F Sullivan, Jennifer R Brennan, Leonard McMillan, and Fernando Pardo-Manuel de Villena
The neonate versus adult mammalian immune system in cardiac repair and regeneration., Susanne Sattler and Nadia Rosenthal
The Non-Coding RNA Ontology (NCRO): a comprehensive resource for the unification of non-coding RNA biology., Jingshan Huang, Karen Eilbeck, Barry Smith, Judith A. Blake, Dejing Dou, Weili Huang, Darren A Natale, Alan Ruttenberg, Jun Huan, Michael T Zimmermann, Guoqian Jiang, Yu Lin, Bin Wu, Harrison J Strachan, Yongqun He, Shaojie Zhang, Xiaowei Wang, Zixing Liu, Glen M Borchert, and Ming Tan
The real cost of sequencing: scaling computation to keep pace with data generation., Paul Muir, Shantao Li, Shaoke Lou, Daifeng Wang, Daniel J Spakowicz, Leonidas Salichos, Jing Zhang, George M. Weinstock, Farren Isaacs, Joel Rozowsky, and Mark Gerstein
The role of 3' untranslated region (3'UTR) in Celf4 regulation of target mRNA., Daniel S. Hawkins
The role of Hbs1l in the developing brain., Thomas Gallup
The role of pancreatic Irx3 in the gut-brain axis., Jaye Sudweeks
The tandem duplicator phenotype as a distinct genomic configuration in cancer., Francesca Menghi, Koichiro Inaki, XingYi Woo, Pooja A Kumar, Krzysztof R. Grzeda, Ankit Malhotra, Vinod Yadav, Hyunsoo Kim, Eladio J Marquez, Duygu Ucar, Phung T Shreckengast, Joel P. Wagner, George MacIntyre, Krishna R Murthy Karuturi, Ralph Scully, James Keck, Jeffrey H Chuang, and Edison Liu
The Transcriptional Signature of Active Tuberculosis Reflects Symptom Status in Extra-Pulmonary and Pulmonary Tuberculosis., Simon Blankley, Christine M Graham, Jacob Turner, Matthew P R Berry, Chloe I Bloom, Zhaohui Xu, Virginia Pascual, Jacques Banchereau, Damien Chaussabel, Ronan Breen, George Santis, Derek M Blankenship, Marc Lipman, and Anne O'Garra
Time of Initiating Enzyme Replacement Therapy Affects Immune Abnormalities and Disease Severity in Patients with Gaucher Disease., Renuka Pudi Limgala, Chidima Ioanou, Matthew Plassmeyer, Mark Ryherd, Lina Kozhaya, Lauren Austin, Cem Abidoglu, Derya Unutmaz, Oral Alpan, and Ozlem Goker-Alpan
Tissue fibroblasts: From bystanders to proactive modulators of homeostasis and disease., Milena B Furtado
Toward more predictive genetic mouse models of Alzheimer's disease., Kristen D Onos, Stacey J. Sukoff Rizzo, Gareth R Howell, and Michael Sasner
Tumor-derived circulating endothelial cell clusters in colorectal cancer., Igor Cima, Say Li Kong, Debarka Sengupta, Iain B Tan, Wai Min Phyo, Daniel Lee, Min Hu, Ciprian Iliescu, Irina Alexander, Wei Lin Goh, Mehran Rahmani, Nur-Afidah Mohamed Suhaimi, Jess H Vo, Joyce A Tai, Joanna H Tan, Clarinda Chua, Rachel Ten, Wan Jun Lim, Min Hoe Chew, Charlotte A E Hauser, Rob M van Dam, Wei-Yen Lim, Shyam Prabhakar, Bing Lim, Poh Koon Koh, Paul Robson, Jackie Y Ying, Axel M Hillmer, and Min-Han Tan
Type 1 diabetes vaccine candidates promote human Foxp3(+)Treg induction in humanized mice., Isabelle Serr, Rainer W Fürst, Peter Achenbach, Martin G Scherm, Füsun Gökmen, Florian Haupt, Eva-Maria Sedlmeier, Annette Knopff, Leonard D. Shultz, Richard A Willis, Anette-Gabriele Ziegler, and Carolin Daniel
Ultra-High Resolution 3D Imaging of Whole Cells., Fang Huang, George Sirinakis, Edward S Allgeyer, Lena K Schroeder, Whitney C Duim, Emil B Kromann, Thomy Phan, Felix E Rivera-Molina, Jordan R Myers, Irnov Irnov, Mark Lessard, Yongdeng Zhang, Mary Ann Handel, Christine Jacobs-Wagner, C Patrick Lusk, James E Rothman, Derek Toomre, Martin J Booth, and Joerg Bewersdorf
View from the heart: cardiac fibroblasts in development, scarring and regeneration., Milena B Furtado, Hieu T Nim, Sarah E Boyd, and Nadia A. Rosenthal
Visualization of RAS/MAPK Signaling In Situ by the Proximity Ligation Assay (PLA)., Zijian Tang and Chengkai Dai
Weak Epistasis Generally Stabilizes Phenotypes in a Mouse Intercross., Anna L. Tyler, Leah Rae Donahue, Gary A. Churchill, and Gregory W. Carter
Whole-exome sequencing identifies recurrent AKT1 mutations in sclerosing hemangioma of lung., Seung-Hyun Jung, Min Sung Kim, Sung-Hak Lee, Hyun-Chun Park, Hyun Joo Choi, Leeso Maeng, Ki Ouk Min, Jeana Kim, Tae In Park, Ok Ran Shin, Tae-Jung Kim, Haidong Xu, Kyo Young Lee, Tae-Min Kim, Sang Yong Song, Charles Lee, Yeun-Jun Chung, and Sug Hyung Lee
WORMHOLE: Novel Least Diverged Ortholog Prediction through Machine Learning., George L. Sutphin, J Matthew Mahoney, Keith Sheppard, David O Walton, and Ron Korstanje
YBR/EiJ mice: a new model of glaucoma caused by genes on chromosomes 4 and 17., K Saidas Nair, Mihai Cosma, Narayanan Raghupathy, Michael A Sellarole, Nicholas G Tolman, Wilhelmine N de Vries, Richard Smith, and Simon W M John
β-catenin-mediated adhesion is required for successful preimplantation mouse embryo development., Daniel Messerschmidt, Wilhelmine N de Vries, Chanchao Lorthongpanich, Sathish Balu, Davor Solter, and Barbara B Knowles