Faculty Research 1990 - 1999

Faculty Research 1990 - 1999



Submissions from 1998

Characterization of the murine gene encoding Aop2 (antioxidant protein 2) and identification of two highly related genes., S A. Phelan, K A. Johnson, D R. Beier, and B Paigen

Genetic analysis of the difference in diet-induced atherosclerosis between the inbred mouse strains SM/J and NZB/BINJ., W A. Pitman, M H. Hunt, C McFarland, and B Paigen


Meiotic prophase arrest with failure of chromosome synapsis in mice deficient for Dmc1, a germline-specific RecA homolog., D L. Pittman, J Cobb, K J. Schimenti, L A. Wilson, D M. Cooper, E Brignull, M A. Handel, and J C. Schimenti

Recombination in the mammalian germ line., D L. Pittman and J C. Schimenti

Identification, characterization, and genetic mapping of Rad51d, a new mouse and human RAD51/RecA-related gene., D L. Pittman, L R. Weinberg, and J C. Schimenti

Differential expression of the zinc finger gene TCF17 in testicular tumors., S A. Przyborski, I Damjanov, B B. Knowles, and S L. Ackerman


Embryonic phenotype of Unc5h3 mutant mice suggests chemorepulsion during the formation of the rostral cerebellar boundary., S A. Przyborski, B B. Knowles, and S L. Ackerman

Differential expression of the zinc finger gene Zfp105 during spermatogenesis., S A. Przyborski, B B. Knowles, M A. Handel, S A. Gurwitch, and S L. Ackerman

Diethylcarbamazine (DEC) does not induce nitric oxide (NO) synthesis., T V. Rajan, L D. Shultz, S Babu, J Doukas, D Greiner, and P Porte

Mature human hematopoietic cells in donor bone marrow complicate interpretation of stem/progenitor cell assays in xenogeneic hematopoietic chimeras., M Ramirez, G A. Rottman, L D. Shultz, and C I. Civin


Epidermal growth factor receptor activity mediates renal cyst formation in polycystic kidney disease., W G. Richards, W E. Sweeney, B K. Yoder, J E. Wilkinson, R P. Woychik, and E D. Avner

Rate of accumulation of Luxol Fast Blue staining material and mitochondrial ATP synthase subunit 9 in motor neuron degeneration mice., J S. Rodman, R Lipman, A Brown, R T. Bronson, and J F. Dice

Insulin-like growth factors and bone: the osteoporosis connection revisited., C J. Rosen and L R. Donahue

Association between serum insulin growth factor-I (IGF-I) and a simple sequence repeat in IGF-I gene: implications for genetic studies of bone mineral density., C J. Rosen, E S. Kurland, D Vereault, R A. Adler, P J. Rackoff, W Y. Craig, S Witte, J Rogers, and J P. Bilezikian

Sterols affecting meiosis: novel chemical syntheses and the biological activity and spectral properties of the synthetic sterols., B Ruan, S Watanabe, J J. Eppig, C Kwoh, N Dzidic, J Pang, W K. Wilson, and G J. Schroepfer

An edited linkage map for the AXB and BXA recombinant inbred mouse strains., S B. Sampson, D C. Higgins, R W. Elliot, B A. Taylor, K K. Lueders, R A. Koza, and B Paigen


Development of the neuromuscular junction: genetic analysis in mice., J R. Sanes, E D. Apel, R W. Burgess, R B. Emerson, G Feng, E Krejci, J Massoulie, Q Nguyen, M Nichol, Y J. Son, G D. Yancopoulos, and al et

Mouse primary spermatocytes can complete two meiotic divisions within the oocyte cytoplasm., I Sasagawa, S Kuretake, J J. Eppig, and R Yanagimachi

Functional genomics in the mouse: phenotype-based mutagenesis screens., J Schimenti and M Bucan

The future of genetic epidemiology., N J. Schork, L R. Cardon, and X Xu

The mouse Gtl2 gene is differentially expressed during embryonic development, encodes multiple alternatively spliced transcripts, and may act as an RNA., Gossler K. Schuster, P Bilinski, T Sado, Smith A. Ferguson, and A Gossler


Subcongenic analysis of the Idd13 locus in NOD/Lt mice: evidence for several susceptibility genes including a possible diabetogenic role for beta 2-microglobulin., D V. Serreze, M Bridgett, H D. Chapman, E Chen, S D. Richard, and E H. Leiter

B lymphocytes are critical antigen-presenting cells for the initiation of T cell-mediated autoimmune diabetes in nonobese diabetic mice., D V. Serreze, S A. Fleming, H D. Chapman, S D. Richard, E H. Leiter, and R M. Tisch

Identification and cloning of a truncated isoform of the cardiac sodium-calcium exchanger in the BALB/c mouse heart., S Shi, B Chang, and S R. Brunnert

Expression of allogeneic MHC class I antigens by transgenic mouse trophoblast does not interfere with the normal course of pregnancy., B Shomer, V Toder, I Egorov, and R Ehrlich

Much ado about minor histocompatibility antigens., E Simpson, D Roopenian, and E Goulmy

Cardiac allograft tolerance: failure to develop in interleukin-4-deficient mice correlates with unusual allosensitization patterns., J H. Sirak, C G. Orosz, D C. Roopenian, E Wakely, and A M. VanBuskirk


Dolly is a clone--and no longer alone [news; comment] [see comments], D Solter

Imprinting., D Solter

A widely expressed betaIII spectrin associated with Golgi and cytoplasmic vesicles., M C. Stankewich, W T. Tse, L L. Peters, Y Ch'ng, K M. John, P R. Stabach, P Devarajan, J S. Morrow, and S E. Lux

Identification of mimotopes for the H4 minor histocompatibility antigen., M A. Strausbauch, W K. Nevala, D C. Roopenian, H E. Stefanski, and P J. Wettstein

Rhino-9J (hr(rh9J)): a new allele at the hairless locus., J P. Sundberg and D Boggess

Mucosotropic papillomavirus infections., J P. Sundberg, R Schlegel, and A B. Jenson

A new allelic series for the underwhite gene on mouse chromosome 15., H O. Sweet, M H. Brilliant, S A. Cook, K R. Johnson, and M T. Davisson

Cryopreservation and orthotopic transplantation of mouse ovaries: new approach in gamete banking., J Sztein, H Sweet, J Farley, and L Mobraaten

Effects of granulocyte/macrophage colony-stimulating factor on the development and differentiation of CD5-positive macrophages and their potential derivation from a CD5-positive B-cell lineage in mice., K Takahashi, K Miyakawa, A A. Wynn, K I. Nakayama, Y Y. Myint, M Naito, L D. Shultz, A Tominaga, and K Takatsu

Bone remodeling and macrophage differentiation in osteopetrosis (op) mutant mice defective in the production of macrophage colony-stimulating factor., H Takatsuka, H Umezu, G Hasegawa, H Usuda, Y Ebe, M Naito, and L D. Shultz

Dystrophic muscle in mice chimeric for expression of alpha5 integrin., D Taverna, M H. Disatnik, H Rayburn, R T. Bronson, J Yang, T A. Rando, and R O. Hynes

Characterization of the mouse Myoc/Tigr gene., S I. Tomarev, E R. Tamm, and B Chang

Characterization of the mouse Prox1 gene., S I. Tomarev, R D. Zinovieva, B Chang, and N L. Hawes

Murine mucopolysaccharidosis type VII: the impact of therapies on the clinical course and pathology in a murine model of lysosomal storage disease., C Vogler, M S. Sands, N Galvin, B Levy, C Thorpe, J Barker, and W S. Sly

The pathophysiological significance of nondesmoglein targets of pemphigus autoimmunity. Development of antibodies against keratinocyte cholinergic receptors in patients with pemphigus vulgaris and pemphigus foliaceus., T N. Vu, T X. Lee, A Ndoye, L D. Shultz, M R. Pittelkow, M V. Dahl, P J. Lynch, and S A. Grando

Full-term development of mice from enucleated oocytes injected with cumulus cell nuclei [see comments], T Wakayama, A C. Perry, M Zuccotti, K R. Johnson, and R Yanagimachi

Hematopoietic cells from -spectrin-deficient mice are sufficient to induce thrombotic events in hematopoietically ablated recipients., N J. Wandersee, J C. Lee, T M. Kaysser, R T. Bronson, and J E. Barker

Networking nomenclature [news], J White, L Maltais, and D Nebert

Insertional mutagenesis in transgenic mice generated by the pronuclear microinjection procedure., R P. Woychik and K Alagramam

Functional genomics in the post-genome era., R P. Woychik, M L. Klebig, M J. Justice, T R. Magnuson, and E D. Avner


Dietary supplementation with mushroom-derived protein-bound glucan does not enhance immune function in young and old mice., D Wu, S N. Han, R T. Bronson, D E. Smith, and S N. Meydani

Aberrant regulation of bone trace elements in motheaten and osteopetrosis mutant mice., G Yamada, S Nakamura, R Haraguchi, M Sakai, K Suzuki, K Miyado, H Hasuwa, Y Ogino, T Minami, Y Tohno, M Blum, and L D. Shultz

Loss of E2F-1 reduces tumorigenesis and extends the lifespan of Rb1(+/-)mice., L Yamasaki, R Bronson, B O. Williams, N J. Dyson, E Harlow, and T Jacks

SHP-1 deficiency in B-lineage cells is associated with heightened lyn protein expression and increased lyn kinase activity., W Yang, S D. Mckenna, H Jiao, M Tabrizi, M A. Lynes, L D. Shultz, and T Yi

Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300., T P. Yao, S P. Oh, M Fuchs, N D. Zhou, L E. Ch'ng, D Newsome, R T. Bronson, E Li, D M. Livingston, and R Eckner

Differential recognition of MBP epitopes in BALB/c mice determines the site of inflammatory disease induction., I Yoshizawa, R Bronson, Nun A. Ben, J R. Richert, M E. Dorf, and Leeman S. Abromson

T-cell responses to myelin basic protein in normal and MBP-deficient mice., I Yoshizawa, R Bronson, M E. Dorf, and Leeman S. Abromson

Genetic interactions suggest that Danforth's short tail (Sd) is a gain-of-function mutation., J Zachgo, R Korn, and A Gossler

Defects in somite formation in lunatic fringe-deficient mice., N Zhang and T Gridley

Expression screening of a yeast artificial chromosome contig refines the location of the mouse H3a minor histocompatibility antigen gene., A R. Zuberi, G J. Christianson, S B. Dave, J A. Bradley, and D C. Roopenian

Positional cloning and molecular characterization of an immunodominant cytotoxic determinant of the mouse H3 minor histocompatibility complex., A R. Zuberi, G J. Christianson, L M. Mendoza, N Shastri, and D C. Roopenian

Submissions from 1997

The mouse rostral cerebellar malformation gene encodes an UNC-5-like protein., S L. Ackerman, L P. Kozak, S A. Przyborski, L A. Rund, B B. Boyer, and B B. Knowles

DNA sequence analysis of Sry alleles (subgenus Mus) implicates misregulation as the cause of C57BL/6J-Y(POS) sex reversal and defines the SRY functional unit., K H. Albrecht and E M. Eicher

Mapping in the region of Danforth's short tail and the localization of tail length modifiers., J B. Alfred, K Rance, B A. Taylor, S J. Phillips, C M. Abbott, and I J. Jackson

LacZ and interleukin-3 expression in vivo after retroviral transduction of marrow-derived human osteogenic mesenchymal progenitors., J A. Allay, J E. Dennis, S E. Haynesworth, M K. Majumdar, D W. Clapp, L D. Shultz, A I. Caplan, and S L. Gerson

Decennial tails., K Artzt and J Schimenti

Informatics--genome and genetic databases., M Ashburner and N Goodman

Expression of hygR in transgenic mice causes resistance to toxic effects of hygromycin B in vivo., J Aubrecht, M E. Goad, E M. Simpson, and R H. Schiestl

Early transplantation to a normal microenvironment prevents the development of Steel hematopoietic stem cell defects., J E. Barker

High plasma HDL concentrations associated with enhanced atherosclerosis in transgenic mice overexpressing lecithin-cholesteryl acyltransferase., A M. Berard, B Foger, A Remaley, R Shamburek, B L. Vaisman, G Talley, B Paigen, R F. Hoyt, S Marcovina, H B. Brewer, and Fojo S. Santamarina

An expanded collection of mouse Y chromosome RDA clones., D E. Bergstrom, H Yan, M M. Sonti, S Narayanswami, J K. Bayleran, and E M. Simpson

A new spontaneous deletion on chromosome 17 including brachyury., P Bilinski, J Schimenti, and A Gossler

Evidence that initiated keratinocytes clonally expand into multiple existing hair follicles during papilloma histogenesis in SENCAR mouse skin., R L. Binder, P M. Gallagher, G R. Johnson, S L. Stockman, B J. Smith, J P. Sundberg, and C J. Conti

A report on the International Nomenclature Workshop held May 1997 at The Jackson Laboratory, Bar Harbor, Maine U.S.A., J A. Blake, M T. Davisson, J T. Eppig, L J. Maltais, S Povey, J A. White, and J E. Womack


The Mouse Genome Database (MGD). A comprehensive public resource of genetic, phenotypic and genomic data. The Mouse Genome Informatics Group., J A. Blake, J E. Richardson, M T. Davisson, and J T. Eppig


B7-1 and B7-2 have overlapping, critical roles in immunoglobulin class switching and germinal center formation., F Borriello, M P. Sethna, S D. Boyd, A N. Schweitzer, E A. Tivol, D Jacoby, T B. Strom, E M. Simpson, G J. Freeman, and A H. Sharpe


Spontaneously colitic C3H/HeJBir mice demonstrate selective antibody reactivity to antigens of the enteric bacterial flora., S L. Brandwein, R P. McCabe, Y Cong, K B. Waites, B U. Ridwan, P A. Dean, T Ohkusa, E H. Birkenmeier, J P. Sundberg, and C O. Elson


Spx1, a novel X-linked homeobox gene expressed during spermatogenesis., W W. Branford, G Q. Zhao, M T. Valerius, M Weinstein, E H. Birkenmeier, L B. Rowe, and S S. Potter


The synaptic protein syntaxin1 is required for cellularization of Drosophila embryos., R W. Burgess, D L. Deitcher, and T L. Schwarz


Kinetic evidence of the regeneration of multilineage hematopoiesis from primitive cells in normal human bone marrow transplanted into immunodeficient mice., J D. Cashman, T Lapidot, J C. Wang, M Doedens, L D. Shultz, P Lansdorp, J E. Dick, and C J. Eaves

Retardation or acceleration of diabetes in NOD/Lt mice mediated by intrathymic administration of candidate beta-cell antigens., Cvrlje M. Cetkovic, I C. Gerling, A Muir, M A. Atkinson, J F. Elliot, and E H. Leiter

Mono(ADP-ribosyl)transferase genes and diabetes in NOD mice. Is there a relationship?, Cvrlje M. Cetkovic, S D. Yang, and E H. Leiter

[In vitro oocyte growth and maturation: a mouse example], F Chesnel, J J. Eppig, and D Boujard


Beta 2-microglobulin-deficient mice are protected from hypergammaglobulinemia and have defective antibody responses because of increased IgG catabolism., G J. Christianson, W Brooks, S Vekasi, E A. Manolfi, J Niles, S L. Roopenian, J B. Roths, R Rothlein, and D C. Roopenian


Enhanced human CD4+ T cell engraftment in beta2-microglobulin-deficient NOD-scid mice., S W. Christianson, D L. Greiner, R A. Hesselton, J H. Leif, E J. Wagar, I B. Schweitzer, T V. Rajan, B Gott, D C. Roopenian, and L D. Shultz

Gata2 maps to mouse chromosome 6., S L. Ciciotte, F Y. Tsai, and L L. Peters


Homozygosity mapping at Alstrom syndrome to chromosome 2p., G B. Collin, J D. Marshall, L R. Cardon, and P M. Nishina

Cerebellar deficient folia (cdf): a new mutation on mouse chromosome 6., S A. Cook, R T. Bronson, L R. Donahue, Arie N. Ben, and M T. Davisson

Sodium/hydrogen exchanger gene defect in slow-wave epilepsy mutant mice., G A. Cox, C M. Lutz, C L. Yang, D Biemesderfer, R T. Bronson, A Fu, P S. Aronson, J L. Noebels, and W N. Frankel

Rules and guidelines for genetic nomenclature in mice: excerpted version. Committee on Standardized Genetic Nomenclature for Mice., M T. Davisson

Cloning, mRNA expression, and chromosomal mapping of mouse and human preprocortistatin., Lecea L. de, Lozano P. Ruiz, P E. Danielson, Kirley J. Peelle, P E. Foye, W N. Frankel, and J G. Sutcliffe

Both T and B cells shed infectious mouse mammary tumor virus., J L. Dzuris, T V. Golovkina, and S R. Ross

Mice lacking mitochondrial uncoupling protein are cold-sensitive but not obese [see comments], S Enerback, A Jacobsson, E M. Simpson, C Guerra, H Yamashita, M E. Harper, and L P. Kozak

Oocyte control of granulosa cell development: how and why., J J. Eppig, F Chesnel, Y Hirao, M J. O'Brien, F L. Pendola, S Watanabe, and K Wigglesworth

Murine oocytes suppress expression of luteinizing hormone receptor messenger ribonucleic acid by granulosa cells., J J. Eppig, K Wigglesworth, F Pendola, and Y Hirao

Chromosome committee reports for the mouse genome., J T. Eppig and L M. Silver

IL-15 mediates anti-tumor effects after cyclophosphamide injection of tumor-bearing mice and enhances adoptive immunotherapy: the potential role of NK cell subpopulations., R Evans, J A. Fuller, G Christianson, D M. Krupke, and A B. Troutt

Function of untranslated regions in the mouse spermatogenesis-specific gene Tcp10 evaluated in transgenic mice., U K. Ewulonu and J C. Schimenti

Cloning, expression, and chromosomal localization of mouse liver bile acid CoA:amino acid N-acyltransferase., C N. Falany, H Fortinberry, E H. Leiter, and S Barnes

Lesions of aryl-hydrocarbon receptor-deficient mice., Salguero P. Fernandez, J M. Ward, J P. Sundberg, and F J. Gonzalez

Hematopoietic precursor cell exhaustion is a cause of proliferative defect in primitive hematopoietic stem cells (PHSC) after chemotherapy., R V. Gardner, C M. Astle, and D E. Harrison

The importance of MHC-I and MHC-II responses in vaccine efficacy against lethal herpes simplex virus type 1 challenge., H Ghiasi, D C. Roopenian, S Slanina, S Cai, A B. Nesburn, and S L. Wechsler

Hormone synthesis and responsiveness of spontaneous granulosa cell tumors in (SWR x SWXJ-9) F1 mice., P M. Gocze, W G. Beamer, J o. de, and D A. Freeman