Faculty Research 1990 - 1999
Submissions from 1997
Cerebellar disorganization characteristic of reeler in scrambler mutant mice despite presence of reelin., D Goldowitz, R C. Cushing, E Laywell, G D'Arcangelo, M Sheldon, H O. Sweet, M Davisson, D Steindler, and T Curran
Generation of a tumorigenic milk-borne mouse mammary tumor virus by recombination between endogenous and exogenous viruses., T V. Golovkina, I Piazzon, I Nepomnaschy, V Buggiano, O l. de, and S R. Ross
Birthdate and cell marker analysis of scrambler: a novel mutation affecting cortical development with a reeler-like phenotype., J L. Gonzalez, C J. Russo, D Goldowitz, H O. Sweet, M T. Davisson, and C A. Walsh
Notch signaling in vertebrate development and disease., T Gridley
The gene encoding protein 4.2 is distinct from the mouse platelet storage pool deficiency mutation pallid., B Gwynn, C Korsgren, C M. Cohen, S L. Ciciotte, and L L. Peters
Cisplatin increases meiotic crossing-over in mice., W H. Hanneman, M E. Legare, S Sweeney, and J C. Schimenti
Molecular analysis of gene conversion in spermatids from transgenic mice., W H. Hanneman, K J. Schimenti, and J C. Schimenti
Genetically null mice reveal a central role for epidermal growth factor receptor in the differentiation of the hair follicle and normal hair development., L A. Hansen, N Alexander, M E. Hogan, J P. Sundberg, A Dlugosz, D W. Threadgill, T Magnuson, and S H. Yuspa
Forebrain overgrowth (fog): a new mutation in the mouse affecting neural tube development., B S. Harris, T Franz, S Ullrich, S Cook, R T. Bronson, and M T. Davisson
Animal models showing accelerated aging are more likely to be useful for pathology than for mechanisms of aging [editorial], D E. Harrison
Short- and long-term multilineage repopulating hematopoietic stem cells in late fetal and newborn mice: models for human umbilical cord blood., D E. Harrison and C M. Astle
Short- and long-term multilineage repopulating hematopoietic stem cells in late fetal and newborn mice: models for human umbilical cord blood., D E. Harrison and C M. Astle
Selection for maximum longevity in mice., D E. Harrison and T H. Roderick
Relative to adult marrow, fetal liver repopulates nearly five times more effectively long-term than short-term., D E. Harrison, R K. Zhong, C T. Jordan, I R. Lemischka, and C M. Astle
New member of the Snf1/AMPK kinase family, Melk, is expressed in the mouse egg and preimplantation embryo., B S. Heyer, J Warsowe, D Solter, B B. Knowles, and S L. Ackerman
An additional 150 SSLP markers typed for the AXB and BXA recombinant inbred mouse strains., D C. Higgins and B Paigen
Analysis of the mechanism(s) of metaphase I arrest in strain LT mouse oocytes: participation of MOS., Y Hirao and J J. Eppig
Parthenogenetic development of Mos-deficient mouse oocytes., Y Hirao and J J. Eppig
Engraftment and development of human CD34(+)-enriched cells from umbilical cord blood in NOD/LtSz-scid/scid mice., C J. Hogan, E J. Shpall, O McNulty, I McNiece, J E. Dick, L D. Shultz, and G Keller
Engraftment and development of human CD34(+)-enriched cells from umbilical cord blood in NOD/LtSz-scid/scid mice., C J. Hogan, E J. Shpall, O McNulty, I McNiece, J E. Dick, L D. Shultz, and G Keller
Isoforms of ankyrin-3 that lack the NH2-terminal repeats associate with mouse macrophage lysosomes., T C. Hoock, L L. Peters, and S E. Lux
Maintenance of somite borders in mice requires the Delta homologue DII1., de Angelis Hrabe, J McIntyre, and A Gossler
Maid: a maternally transcribed novel gene encoding a potential negative regulator of bHLH proteins in the mouse egg and zygote., S Y. Hwang, B Oh, A Fuchtbauer, E M. Fuchtbauer, K R. Johnson, D Solter, and B B. Knowles
Maid: a maternally transcribed novel gene encoding a potential negative regulator of bHLH proteins in the mouse egg and zygote., S Y. Hwang, B Oh, A Fuchtbauer, E M. Fuchtbauer, K R. Johnson, D Solter, and B B. Knowles
The combination of epidermal growth factor and transforming growth factor-beta induces novel phenotypic changes in mouse liver stem cell lines., R J. Isfort, D B. Cody, S B. Stuard, C J. Randall, C Miller, G M. Ridder, C J. Doersen, W G. Richards, B K. Yoder, J E. Wilkinson, and R P. Woychik
Identification and genetic mapping of a new polycystic kidney disease on mouse chromosome 8., P M. Janaswami, E H. Birkenmeier, S A. Cook, L B. Rowe, R T. Bronson, and M T. Davisson
T-cell receptors: is the repertoire inherently MHC-specific?, C A. Janeway, A V. Chervonsky, and D Sant'Angelo
Multiplicity of uses of monoclonal antibodies that define papillomavirus linear immunodominant epitopes., A B. Jenson, M C. Jenson, L Cowsert, S J. Ghim, and J P. Sundberg
Genomic organization and chromosomal localization of the mouse snail (Sna) gene., R Jiang, N G. Copeland, D J. Gilbert, N A. Jenkins, and T Gridley
Gene targeting: things go better with Cre., R Jiang and T Gridley
Gene targeting: things go better with Cre., R Jiang and T Gridley
Macrophages from motheaten and viable motheaten mutant mice show increased proliferative responses to GM-CSF: detection of potential HCP substrates in GM-CSF signal transduction., H Jiao, W Yang, K Berrada, M Tabrizi, L Shultz, and T Yi
Mouse chromosome 18., K R. Johnson and M T. Davisson
A major gene affecting age-related hearing loss in C57BL/6J mice., K R. Johnson, L C. Erway, S A. Cook, J F. Willott, and Q Y. Zheng
K-ras is an essential gene in the mouse with partial functional overlap with N-ras [published erratum appears in Genes Dev 1997 Dec 1;11(23):3277], L Johnson, D Greenbaum, K Cichowski, K Mercer, E Murphy, E Schmitt, R T. Bronson, H Umanoff, W Edelmann, R Kucherlapati, and T Jacks
Using targeted large deletions and high-efficiency N-ethyl-N-nitrosourea mutagenesis for functional analyses of the mammalian genome., M J. Justice, B Zheng, R P. Woychik, and A Bradley
CSF-1-induced and constitutive Il6 gene expression in mouse macrophages: evidence for PKC-dependent and -independent pathways., S J. Kamdar, J A. Fuller, and R Evans
CSF-1-induced and constitutive Il6 gene expression in mouse macrophages: evidence for PKC-dependent and -independent pathways., S J. Kamdar, J A. Fuller, and R Evans
Priming of mouse macrophages with the macrophage colony-stimulating factor (CSF-1) induces a variety of pathways that regulate expression of the interleukin 6 (Il6) and granulocyte-macrophage colony-stimulating factor (Csfgm) genes., S J. Kamdar, J A. Fuller, S I. Nishikawa, and R Evans
Thrombosis and secondary hemochromatosis play major roles in the pathogenesis of jaundiced and spherocytic mice, murine models for hereditary spherocytosis., T M. Kaysser, N J. Wandersee, R T. Bronson, and J E. Barker
Limatin (LIMAB1), an actin-binding LIM protein, maps to mouse chromosome 19 and human chromosome 10q25, a region frequently deleted in human cancers., A C. Kim, L L. Peters, J H. Knoll, H u. Van, S L. Ciciotte, P W. Kleyn, and A H. Chishti
Targeted disruption of the pemphigus vulgaris antigen (desmoglein 3) gene in mice causes loss of keratinocyte cell adhesion with a phenotype similar to pemphigus vulgaris., P J. Koch, M G. Mahoney, H Ishikawa, L Pulkkinen, J Uitto, L D. Shultz, G F. Murphy, Menezes D. Whitaker, and J R. Stanley
Inter-strain graft-vs.-host disease T-cell responses to immunodominant minor histocompatibility antigens., R Korngold, C Leighton, L E. Mobraaten, and M A. Berger
The Jagged2 gene maps to chromosome 12 and is a candidate for the lgl and sm mutations., Y Lan, R Jiang, C Shawber, G Weinmaster, and T Gridley
Carboxypeptidase E and obesity in the mouse., E H. Leiter
Mapping to chromosomes 1 and 12 of mouse homologs of human protein tyrosine phosphatase, receptor-type, related genes encoding pancreatic beta cell autoantigens., E H. Leiter, H Tsumura, D V. Serreze, H D. Chapman, D U. Rabin, M S. Lan, and A L. Notkins
Multiple pigmented cutaneous papules associated with a novel canine papillomavirus in an immunosuppressed dog., N e. Le, G Orth, J P. Sundberg, P Cassonnet, L Poisson, M T. Masson, C George, and L Longeart
Vertebrate homologues of C. elegans UNC-5 are candidate netrin receptors., E D. Leonardo, L Hinck, M Masu, Masu K. Keino, S L. Ackerman, and Lavigne M. Tessier
Guidance of developing axons by netrin-1 and its receptors., E D. Leonardo, L Hinck, M Masu, Masu K. Keino, A Fazeli, E T. Stoeckli, S L. Ackerman, R A. Weinberg, and Lavigne M. Tessier
Genetic and physical maps of the stargazer locus on mouse chromosome 15., V A. Letts, A Valenzuela, J P. Kirley, H O. Sweet, M T. Davisson, and W N. Frankel
Beta2-microglobulin-deficient mice are resistant to bullous pemphigoid., Z Liu, D C. Roopenian, X Zhou, G J. Christianson, L A. Diaz, D D. Sedmak, and C L. Anderson
Targeted ablation of the vitamin D receptor: an animal model of vitamin D-dependent rickets type II with alopecia., Y C. Li, A E. Pirro, M Amling, G Delling, R Baron, R Bronson, and M B. Demay
Neuropeptide Y receptor genes on human chromosome 4q31-q32 map to conserved linkage groups on mouse chromosomes 3 and 8., C M. Lutz, W N. Frankel, J E. Richards, and D A. Thompson
Neuropeptide Y receptor genes mapped in human and mouse: receptors with high affinity for pancreatic polypeptide are not clustered with receptors specific for neuropeptide Y and peptide YY., C M. Lutz, J E. Richards, K L. Scott, S Sinha, Feng T. Yang, W N. Frankel, and D A. Thompson
The Danforth's short tail mutation acts cell autonomously in notochord cells and ventral hindgut endoderm., R Maatman, J Zachgo, and A Gossler
Mouse angiotensin receptor genes Agtr1a and Agtr1b map to chromosomes 13 and 3., T E. MacTaggart, M Ito, O Smithies, and S W. John
Allele-specific PCR assays for the tub and cpefat mutations., T Maddatu and J K. Naggert
Intron/exon structure confirms that mouse Zfy1 and Zfy2 are members of the ZFY gene family., C L. Mahaffey, J K. Bayleran, G Y. Yeh, T C. Lee, D C. Page, and E M. Simpson
Spontaneous Leydig cell tumors in inbred laboratory mice., M Mahler and J P. Sundberg
Spontaneous Leydig cell tumors in inbred laboratory mice., M Mahler and J P. Sundberg
Rules and guidelines for mouse gene nomenclature: a condensed version. International Committee on Standardized Genetic Nomenclature for Mice., Lois J. Maltais, Judith A. Blake, Janan T. Eppig, and Muriel T. Davisson
Prolonged survival of mouse skin allografts in recipients treated with donor splenocytes and antibody to CD40 ligand., T G. Markees, N E. Phillips, R J. Noelle, L D. Shultz, J P. Mordes, D L. Greiner, and A A. Rossini
Genealogy, natural history, and phenotype of Alstrom syndrome in a large Acadian kindred and three additional families., J D. Marshall, M D. Ludman, S E. Shea, S R. Salisbury, S M. Willi, R G. LaRoche, and P M. Nishina
Preservation of functioning human thyroid organoids in the scid mouse. IV. In vivo selection of an intrathyroidal T cell receptor repertoire., A Martin, N Matsuoka, J Zhang, A Zhou, M Nakashima, P Unger, A E. Schwartz, E W. Friedman, L D. Shultz, and T F. Davies
Impaired fertility in mice deficient for the testicular germ-cell protease PC4., M Mbikay, H Tadros, N Ishida, C P. Lerner, Lamirande E. De, A Chen, Alfy M. El, Y Clermont, N G. Seidah, M Chretien, C Gagnon, and E M. Simpson
Roles of the imprinted gene Igf2 and paternal duplication of distal chromosome 7 in the perinatal abnormalities of androgenetic mouse chimeras., K J. McLaughlin, H Kochanowski, D Solter, G Schwarzkopf, P E. Szabo, and J R. Mann
Developmental consequences of two paternal copies of imprinted chromosome region distal 7 in mice., K J. McLaughlin, D Solter, and J Mann
Minors held by majors: the H13 minor histocompatibility locus defined as a peptide/MHC class I complex., L M. Mendoza, P Paz, A Zuberi, G Christianson, D C. Roopenian, and N Shastri
Role of the agouti gene in obesity., E J. Michaud, R L. Mynatt, R J. Miltenberger, M L. Klebig, J E. Wilkinson, M B. Zemel, W O. Wilkison, and R P. Woychik
Vesicle formation and follicular root sheath separation in mice homozygous for deleterious alleles at the balding (bal) locus., X Montagutelli, A Lalouette, H J. Boulouis, J L. Guenet, and J P. Sundberg
C57BL/6J skin lesion problem eliminated., David D. Myers
The genetics of obesity., J Naggert, T Harris, and M North
The atherogenic lipoprotein phenotype is not caused by a mutation in the coding region of the low density lipoprotein receptor gene., J K. Naggert, A Recinos, J E. Lamerdin, R M. Krauss, and P M. Nishina
An additional 136 SSLP markers typed for the AXB and BXA recombinant inbred mouse strains., J K. Naggert, K L. Svenson, L Lin, Y Cheah, P M. Nishina, J Mu, T R. Devereux, M You, and B Paigen
Macrophage differentiation and granulomatous inflammation in osteopetrotic mice (op/op) defective in the production of CSF-1., M Naito, S Umeda, K Takahashi, and L D. Shultz
Mouse Ly-49A interrupts early signaling events in natural killer cell cytotoxicity and functionally associates with the SHP-1 tyrosine phosphatase., M C. Nakamura, E C. Niemi, M J. Fisher, L D. Shultz, W E. Seaman, and J C. Ryan
Abnormal development and differentiation of macrophages and dendritic cells in viable motheaten mutant mice deficient in haematopoietic cell phosphatase., K Nakayama, K Takahashi, L D. Shultz, K Miyakawa, and K Tomita
Cloning and expression analysis of mouse Cclp1, a new gene encoding a coiled-coil-like protein., Trauth K. Noben, J K. Naggert, and P M. Nishina
mdfw: a deafness susceptibility locus that interacts with deaf waddler (dfw)., Trauth K. Noben, Q Y. Zheng, K R. Johnson, and P M. Nishina
An interleukin 4 (IL-4)-independent pathway for CD4+ T cell IL-4 production is revealed in IL-4 receptor-deficient mice., Trauth N. Noben, L D. Shultz, F Brombacher, J F. Urban, H Gu, and W E. Paul
Molecular characterization of TUB, TULP1, and TULP2, members of the novel tubby gene family and their possible relation to ocular diseases., M A. North, J K. Naggert, Y Yan, Trauth K. Noben, and P M. Nishina
Genetic mapping of the C-type natriuretic peptide receptor (Npr2) gene to mouse chromosome 4., E Nuglozeh and L P. Kozak
Spindlin, a major maternal transcript expressed in the mouse during the transition from oocyte to embryo., B Oh, S Y. Hwang, D Solter, and B B. Knowles
Disproportionate micromelia (Dmm) in mice caused by a mutation in the C-propeptide coding region of Col2a1., J M. Pace, Y Li, R E. Seegmiller, C Teuscher, B A. Taylor, and B R. Olsen
Mouse TCOF1 is expressed widely, has motifs conserved in nucleolar phosphoproteins, and maps to chromosome 18., W A. Paznekas, N Zhang, T Gridley, and E W. Jabs
The gene encoding the transcription factor Spi-B maps to mouse chromosome 7., L L. Peters, S L. Ciciotte, G H. Su, and M C. Simon
Genetic markers in the Tuvan population of Todja, Siberia., L E. Pospelov, A G. Matrakshin, L S. Erdynieva, A F. Malenko, K I. Afanasiev, G A. Rubtsova, I K. Egorov, V V. Yeremeyev, and A S. Apt
Decreased retinal ganglion cell number and misdirected axon growth associated with fissure defects in Bst/+ mutant mice., D S. Rice, Q Tang, R W. Williams, B S. Harris, M T. Davisson, and D Goldowitz
The mouse gene expression database GXD., M Ringwald, G L. Davis, A G. Smith, L E. Trepanier, D A. Begley, J E. Richardson, and J T. Eppig
A new dominant retinal degeneration (Rd4) associated with a chromosomal inversion in the mouse., T H. Roderick, B Chang, N L. Hawes, and J R. Heckenlively
Beyond one gene-one disease: alternative strategies for deciphering genetic determinants of osteoporosis [editorial], J Rogers, M C. Mahaney, W G. Beamer, L R. Donahue, and C J. Rosen
Circulating and skeletal insulin-like growth factor-I (IGF-I) concentrations in two inbred strains of mice with different bone mineral densities [see comments], C J. Rosen, H P. Dimai, D Vereault, L R. Donahue, W G. Beamer, J Farley, S Linkhart, T Linkhart, S Mohan, and D J. Baylink
Mouse mammary tumor virus (MMTV), a retrovirus that exploits the immune system. Genetics of susceptibility to MMTV infection., S R. Ross, J L. Dzuris, T V. Golovkina, W C. Clemmons, and den Hoogen van
Murine mucopolysaccharidosis type VII: long term therapeutic effects of enzyme replacement and enzyme replacement followed by bone marrow transplantation., M S. Sands, C Vogler, A Torrey, B Levy, B Gwynn, J Grubb, W S. Sly, and E H. Birkenmeier
Gene therapy for murine mucopolysaccharidosis type VII., M S. Sands, J H. Wolfe, E H. Birkenmeier, J E. Barker, C Vogler, W S. Sly, T Okuyama, B Freeman, A Nicholes, N Muzyczka, P L. Chang, and H R. Axelrod
Gastric squamous cell carcinoma in three llamas., E A. Sartin, B M. Waldridge, D W. Carter, G A. Herrera, Kinnucan M. Toivio, S D. Lenz, D G. Pugh, D F. Wolfe, and J P. Sundberg
Mouse natriuretic peptide receptor 3 gene maps to proximal chromosome 15., O V. Savinova, N Matsukawa, O Smithies, and S W. John
Evidence for cyclophosphamide-induced gene conversion and mutation in mouse germ cells., K J. Schimenti, W H. Hanneman, and J C. Schimenti
Initiation of autoimmune diabetes in NOD/Lt mice is MHC class I-dependent., D V. Serreze, H D. Chapman, D S. Varnum, I Gerling, E H. Leiter, and L D. Shultz
To save or not to save: the role of repositories in a period of rapidly expanding development of genetically engineered strains of mice., J J. Sharp and L E. Mobraaten