Faculty Research 1990 - 1999

Faculty Research 1990 - 1999



Submissions from 1998

CSF-1 (M-CSF) differentially sensitizes mononuclear phagocyte subpopulations to endotoxin in vivo: a potential pathway that regulates the severity of gram-negative infections., A I. Chapoval, S J. Kamdar, S G. Kremlev, and R Evans

Delayed immune aging in diet-restricted B6CBAT6 F1 mice is associated with preservation of naive T cells., J Chen, C M. Astle, and D E. Harrison

Subtle conformational changes induced in major histocompatibility complex class II molecules by binding peptides., A V. Chervonsky, R M. Medzhitov, L K. Denzin, A K. Barlow, A Y. Rudensky, and C A. Janeway

Human DCTN1: genomic structure and evaluation as a candidate for Alstrom syndrome., G B. Collin, P M. Nishina, J D. Marshall, and J K. Naggert


CD4+ T cells reactive to enteric bacterial antigens in spontaneously colitic C3H/HeJBir mice: increased T helper cell type 1 response and ability to transfer disease., Y Cong, S L. Brandwein, R P. McCabe, A Lazenby, E H. Birkenmeier, J P. Sundberg, and C O. Elson

Factors affecting ectopic gene conversion in mice., D M. Cooper, K J. Schimenti, and J C. Schimenti

Identification of the mouse neuromuscular degeneration gene and mapping of a second site suppressor allele., G A. Cox, C L. Mahaffey, and W N. Frankel

Chromosomal locations of the mouse fatty acid oxidation genes Cpt1a, Cpt1b, Cpt2, Acadvl, and metabolically related Crat gene., K B. Cox, K R. Johnson, and P A. Wood


Distinct requirements for evoked and spontaneous release of neurotransmitter are revealed by mutations in the Drosophila gene neuronal-synaptobrevin., D L. Deitcher, A Ueda, B A. Stewart, R W. Burgess, Y Kidokoro, and T L. Schwarz


The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity., Lecea L. de, T S. Kilduff, C Peyron, X Gao, P E. Foye, P E. Danielson, C Fukuhara, E L. Battenberg, V T. Gautvik, F S. Bartlett, W N. Frankel, d e. van, F E. Bloom, K M. Gautvik, and J G. Sutcliffe

The uterine environment enhances cognitive competence., V H. Denenberg, B J. Hoplight, and L E. Mobraaten


Major histocompatibility complex class I-restricted T cells are required for all but the end stages of diabetes development in nonobese diabetic mice and use a prevalent T cell receptor alpha chain gene rearrangement., T P. DiLorenzo, R T. Graser, T Ono, G J. Christianson, H D. Chapman, D C. Roopenian, S G. Nathenson, and D V. Serreze

Alkaline phosphatase levels and osteoprogenitor cell numbers suggest bone formation may contribute to peak bone density differences between two inbred strains of mice., H P. Dimai, T A. Linkhart, S G. Linkhart, L R. Donahue, W G. Beamer, C J. Rosen, J R. Farley, and D J. Baylink


Distribution of epithelial ankyrin (Ank3) spliceoforms in renal proximal and distal tubules., R B. Doctor, J Chen, L L. Peters, S E. Lux, and L J. Mandel

Factors affecting the developmental competence of mouse oocytes grown in vitro: follicle-stimulating hormone and insulin., J J. Eppig, M J. O'Brien, F L. Pendola, and S Watanabe


Mouse oocytes suppress cAMP-induced expression of LH receptor mRNA by granulosa cells in vitro., J J. Eppig, F L. Pendola, and K Wigglesworth

Informatics for mouse genetics and genome mapping., J T. Eppig, J A. Blake, M T. Davisson, and J E. Richardson

CSF-1 regulation of Il6 gene expression by murine macrophages: a pivotal role for GM-CSF., R Evans, L D. Shultz, G Dranoff, J A. Fuller, and S J. Kamdar

The Polycomb-group gene eed is required for normal morphogenetic movements during gastrulation in the mouse embryo., C Faust, K A. Lawson, N J. Schork, B Thiel, and T Magnuson

Blockade of CD40-CD154 interferes with human T cell engraftment in scid mice., T M. Foy, M McIlraith, S R. Masters, J J. Dunn, A A. Rossini, L D. Shultz, R A. Hesselton, E J. Wagar, P E. Lipsky, R J. Noelle, and D L. Greiner

Mouse strain backgrounds: more than black and white [letter], W N. Frankel


Sterol carrier protein 2 participates in hypersecretion of biliary cholesterol during gallstone formation in genetically gallstone-susceptible mice., M Fuchs, F Lammert, D Q. Wang, B Paigen, M C. Carey, and D E. Cohen

Assignment of the murine Notch2 and Notch3 genes to chromosomes 3 and 17., X Gao, N G. Copeland, D J. Gilbert, N A. Jenkins, and T Gridley

A critical role for DNA end-joining proteins in both lymphogenesis and neurogenesis., Y Gao, Y Sun, K M. Frank, P Dikkes, Y Fujiwara, K J. Seidl, J M. Sekiguchi, G A. Rathbun, W Swat, J Wang, and R T. Bronson

An essential role for Fas ligand in transplantation tolerance induced by donor bone marrow., J F. George, S D. Sweeney, J K. Kirklin, E M. Simpson, D R. Goldstein, and J M. Thomas

B and T cells are required for mouse mammary tumor virus spread within the mammary gland., T V. Golovkina, J P. Dudley, and S R. Ross


A novel membrane protein is a mouse mammary tumor virus receptor., T V. Golovkina, J Dzuris, den Hoogen van, A B. Jaffe, P C. Wright, S M. Cofer, and S R. Ross

The LabFlow system for workflow management in large scale biology research laboratories., N Goodman, S Rozen, and L D. Stein

The LabBase system for data management in large scale biology research laboratories., N Goodman, S Rozen, L D. Stein, and A G. Smith

Prolonged survival of rat islet and skin xenografts in mice treated with donor splenocytes and anti-CD154 monoclonal antibody., E J. Gordon, T G. Markees, N E. Phillips, R J. Noelle, L D. Shultz, J P. Mordes, A A. Rossini, and D L. Greiner

Somitogenesis., A Gossler and d e. Hrabe


Advances in DNA diagnostics., J H. Graber, M J. O'Donnell, C L. Smith, and C R. Cantor


SCID mouse models of human stem cell engraftment., D L. Greiner, R A. Hesselton, and L D. Shultz

Abnormal nonshivering thermogenesis in mice with inherited defects of fatty acid oxidation., C Guerra, R A. Koza, K Walsh, D M. Kurtz, P A. Wood, and L P. Kozak

Emergence of brown adipocytes in white fat in mice is under genetic control. Effects on body weight and adiposity., C Guerra, R A. Koza, H Yamashita, K Walsh, and L P. Kozak

Mammalian male and female germ cells express a germ cell-specific Y-Box protein, MSY2., W Gu, S Tekur, R Reinbold, J J. Eppig, Y C. Choi, J Z. Zheng, M T. Murray, and N B. Hecht

Intracisternal A-particle element transposition into the murine beta-glucuronidase gene correlates with loss of enzyme activity: a new model for beta-glucuronidase deficiency in the C3H mouse., B Gwynn, K Lueders, M S. Sands, and E H. Birkenmeier

Recessive mutations in the gene encoding the tubby-like protein TULP1 in patients with retinitis pigmentosa., S A. Hagstrom, M A. North, P L. Nishina, E L. Berson, and T P. Dryja

Sexual dimorphism in the regulation of mammalian meiosis., M A. Handel and J J. Eppig


Effect of the viable-yellow (A(vy)) agouti allele on skin tumorigenesis and humoral hypercalcemia in v-Ha-ras transgenic TGxAC mice., L A. Hansen, D E. Malarkey, J E. Wilkinson, M Rosenberg, R E. Woychik, and R W. Tennant


Reduced fertility in female mice lacking copper-zinc superoxide dismutase., Y S. Ho, M Gargano, J Cao, R T. Bronson, I Heimler, and R J. Hutz

Spectrin localization in osteoclasts: immunocytochemistry, cloning, and partial sequencing., S J. Hunter, C V. Gay, P A. Osdoby, and L L. Peters

Encyclopedia of the mouse genome VII. Mouse chromosome 15., K Huppi, D Siwarski, and V Letts

Lactation-induced WAP-SV40 Tag transgene expression in C57BL/6J mice leads to mammary carcinoma., M R. Husler, K A. Kotopoulis, J P. Sundberg, B J. Tennent, S V. Kunig, and B B. Knowles

Hyperleptinemia and leptin receptor variant Asp600Asn in the obese, hyperinsulinemic KK mouse strain., M Igel, B A. Taylor, S J. Phillips, W Becker, L Herberg, and H G. Joost

Characterization of growth factor responsiveness and alterations in growth factor homeostasis involved in the tumorigenic conversion of mouse oval cells., R J. Isfort, D B. Cody, W G. Richards, B K. Yoder, J E. Wilkinson, and R P. Woychik


Defects in limb, craniofacial, and thymic development in Jagged2 mutant mice., R Jiang, Y Lan, H D. Chapman, C Shawber, C R. Norton, D V. Serreze, G Weinmaster, and T Gridley

The Slug gene is not essential for mesoderm or neural crest development in mice., R Jiang, Y Lan, C R. Norton, J P. Sundberg, and T Gridley

Genomic organization, expression and chromosomal localization of the mouse Slug (Slugh) gene., R Jiang, C R. Norton, N G. Copeland, D J. Gilbert, N A. Jenkins, and T Gridley

The original shaker-with-syndactylism mutation (sy) is a contiguous gene deletion syndrome., K R. Johnson, S A. Cook, and Q Y. Zheng

Encyclopedia of the mouse genome VII. Mouse chromosome 18., K R. Johnson and M T. Davisson

A new spontaneous mouse mutation of Hoxd13 with a polyalanine expansion and phenotype similar to human synpolydactyly., K R. Johnson, H O. Sweet, L R. Donahue, Bailey P. Ward, R T. Bronson, and M T. Davisson


Essential iris atrophy, pigment dispersion, and glaucoma in DBA/2J mice., S W. John, R S. Smith, O V. Savinova, N L. Hawes, B Chang, D Turnbull, M Davisson, T H. Roderick, and J R. Heckenlively


Follicular dendritic cell (FDC) precursors in primary lymphoid tissues., Z F. Kapasi, D Qin, W G. Kerr, Vilbois M. Kosco, L D. Shultz, J G. Tew, and A K. Szakal


A map of 75 human ribosomal protein genes., N Kenmochi, T Kawaguchi, S Rozen, E Davis, N Goodman, T J. Hudson, T Tanaka, and D C. Page

Utilization of microhomologous recombination in yeast to generate targeting constructs for mammalian genes., I Khrebtukova, E J. Michaud, C M. Foster, K L. Stark, D J. Garfinkel, and R P. Woychik

Genetic models for non insulin dependent diabetes mellitus in rodents., J H. Kim, P M. Nishina, and J K. Naggert

Essential roles for the Abl and Arg tyrosine kinases in neurulation., A J. Koleske, A M. Gifford, M L. Scott, M Nee, R T. Bronson, K A. Miczek, and D Baltimore


Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome., M S. Ko, T A. Threat, X Wang, J H. Horton, Y Cui, E Pryor, J Paris, Smith J. Wells, J R. Kitchen, L B. Rowe, J Eppig, T Satoh, L Brant, H Fujiwara, S Yotsumoto, and H Nakashima

Patchy fur, a mouse coat mutation associated with X-Y nondisjunction, maps to the pseudoautosomal boundary region., O Korobova, P W. Lane, J Perry, S Palmer, A Ashworth, M T. Davisson, and N Arnheim

Cytokine release by macrophages after interacting with CSF-1 and extracellular matrix proteins: characteristics of a mouse model of inflammatory responses in vitro., S G. Kremlev, A I. Chapoval, and R Evans


Transgene expression of steel factor in the basal layer of epidermis promotes survival, proliferation, differentiation and migration of melanocyte precursors., T Kunisada, H Yoshida, H Yamazaki, A Miyamoto, H Hemmi, E Nishimura, L D. Shultz, S Nishikawa, and S Hayashi


Normal growth hormone secretory reserve in men with idiopathic osteoporosis and reduced circulating levels of insulin-like growth factor-I., E S. Kurland, F K. Chan, C J. Rosen, and J P. Bilezikian


The mouse pudgy mutation disrupts Delta homologue Dll3 and initiation of early somite boundaries., K Kusumi, E S. Sun, A W. Kerrebrock, R T. Bronson, D C. Chi, M S. Bulotsky, J B. Spencer, B W. Birren, W N. Frankel, and E S. Lander


Mouse cell surface antigens: nomenclature and immunophenotyping., L Lai, N Alaverdi, L Maltais, and H C. Morse

The gene encoding the multispecific organic anion transporter (Cmoat) of the hepatocyte canalicular membrane maps to mouse chromosome 19., F Lammert, D E. Cohen, B Paigen, M C. Carey, and D R. Beier

Localization of the ileal sodium-bile salt cotransporter gene (Slc10a2) to mouse chromosome 8., F Lammert, B Paigen, and M C. Carey

Juvenile bare: a new hair loss mutation on chromosome 7 of the mouse., P W. Lane, R T. Bronson, S A. Cook, Bailey P. Ward, L R. Donahue, and M T. Davisson

A very large protein with diverse functional motifs is deficient in rjs (runty, jerky, sterile) mice., A L. Lehman, Y Nakatsu, A Ching, R T. Bronson, R J. Oakey, Hrynko N. Keiper, J N. Finger, Pierre D. Durham, D B. Horton, J M. Newton, M F. Lyon, and M H. Brilliant

NIDDM genes in mice: deleterious synergism by both parental genomes contributes to diabetogenic thresholds., E H. Leiter, P C. Reifsnyder, K Flurkey, H J. Partke, E Junger, and L Herberg

Mouse inbred strains., Pierce M. Lennon and J T. Eppig

The mouse stargazer gene encodes a neuronal Ca2+-channel gamma subunit [see comments], V A. Letts, R Felix, G H. Biddlecome, J Arikkath, C L. Mahaffey, A Valenzuela, F S. Bartlett, Y Mori, K P. Campbell, and W N. Frankel


A specific, nonproliferative role for E2F-5 in choroid plexus function revealed by gene targeting., G J. Lindeman, L Dagnino, S Gaubatz, Y Xu, R T. Bronson, H B. Warren, and D M. Livingston

Additional evidence that the K-ras protooncogene is a candidate for the major mouse pulmonary adenoma susceptibility (Pas-1) gene., L Lin, M F. Festing, T R. Devereux, K A. Crist, S C. Christiansen, Y Wang, A Yang, K Svenson, B Paigen, A M. Malkinson, and M You

cDNA sequence and chromosomal localization of mouse Dlgh3 gene adjacent to the BRCA1 tumor suppressor locus., L Lin, L L. Peters, S L. Ciciotte, and A H. Chishti


Altered calcium channel currents in Purkinje cells of the neurological mutant mouse leaner., N M. Lorenzon, C M. Lutz, W N. Frankel, and K G. Beam

A model system for studying the integration of molecular biology databases., J Macauley, H Wang, and N Goodman

Comparison of four diagnostic methods for detection of Helicobacter species in laboratory mice., M Mahler, H G. Bedigian, B L. Burgett, R J. Bates, M E. Hogan, and J P. Sundberg


Differential susceptibility of inbred mouse strains to dextran sulfate sodium-induced colitis., M Mahler, I J. Bristol, E H. Leiter, A E. Workman, E H. Birkenmeier, C O. Elson, and J P. Sundberg

The molecular and functional characterization of a dominant minor H antigen, H60., S Malarkannan, P P. Shih, P A. Eden, T Horng, A R. Zuberi, G Christianson, D Roopenian, and N Shastri

Standardized genetic nomenclature for mice., L Maltais and M T. Davisson


Long-term survival of skin allografts induced by donor splenocytes and anti-CD154 antibody in thymectomized mice requires CD4(+) T cells, interferon-gamma, and CTLA4., T G. Markees, N E. Phillips, E J. Gordon, R J. Noelle, L D. Shultz, J P. Mordes, D L. Greiner, and A A. Rossini


Mice heterozygous for a mutation at the Nf2 tumor suppressor locus develop a range of highly metastatic tumors., A I. McClatchey, I Saotome, K Mercer, D Crowley, J F. Gusella, R T. Bronson, and T Jacks


Murine cytomegalovirus is not associated with alopecia areata in C3H/HeJ mice [letter], K J. McElwee, D Boggess, B Burgett, R Bates, H G. Bedigan, J P. Sundberg, and L E. King


Experimental induction of alopecia areata-like hair loss in C3H/HeJ mice using full-thickness skin grafts., K J. McElwee, D Boggess, L E. King, and J P. Sundberg

Comparison of alopecia areata in human and nonhuman mammalian species., K J. McElwee, D Boggess, T Olivry, R F. Oliver, D Whiting, D J. Tobin, J C. Bystryn, L E. King, and J P. Sundberg

Ursodeoxycholic acid and cholesterol induce enterohepatic cycling of bilirubin in rodents., Sanchez N. Mendez, M A. Brink, B Paigen, and M C. Carey

Establishment and characterization of pro-B cell lines from motheaten mutant mouse defective in SHP-1 protein tyrosine phosphatase., A Miyamoto, T Kunisada, H Yamazaki, K Miyake, S I. Nishikawa, T Sudo, L D. Shultz, and S I. Hayashi


The molecular biology of polycystic kidney disease., N S. Murcia, R P. Woychik, and E D. Avner

Mouse chromosome classification by radial basis function network with fast orthogonal search., M T. Musavi, R J. Bryant, M Qiao, M T. Davisson, E C. Akeson, and B D. French

Molecular characterization of a novel tubby gene family member, TULP3, in mouse and humans., P M. Nishina, M A. North, A Ikeda, Y Yan, and J K. Naggert


SPIN, a substrate in the MAP kinase pathway in mouse oocytes., B Oh, A Hampl, J J. Eppig, D Solter, and B B. Knowles


Natriuretic peptide receptor 1 expression influences blood pressures of mice in a dose-dependent manner., P M. Oliver, S W. John, K E. Purdy, R Kim, N Maeda, M F. Goy, and O Smithies

Molecular basis for the rhino Yurlovo (hr(rhY)) phenotype: severe skin abnormalities and female reproductive defects associated with an insertion in the hairless gene., A A. Panteleyev, W Ahmad, A M. Malashenko, E L. Ignatieva, R Paus, J P. Sundberg, and A M. Christiano

Molecular and functional aspects of the hairless (hr) gene in laboratory rodents and humans., A A. Panteleyev, R Paus, W Ahmad, J P. Sundberg, and A M. Christiano

High-resolution mapping of the truncate (tc) locus on mouse chromosome 6., M N. Pavlova, A M. Clark, and A Gossler

Efficient and rapid induction of a chronic myelogenous leukemia-like myeloproliferative disease in mice receiving P210 bcr/abl-transduced bone marrow., W S. Pear, J P. Miller, L Xu, J C. Pui, B Soffer, R C. Quackenbush, A M. Pendergast, R Bronson, J C. Aster, M L. Scott, and D Baltimore


Lymphadenopathy, elevated serum IgE levels, autoimmunity, and mast cell accumulation in flaky skin mutant mice., S C. Pelsue, P A. Schweitzer, I B. Schweitzer, S W. Christianson, B Gott, J P. Sundberg, W G. Beamer, and L D. Shultz

Encyclopedia of the mouse genome VII. Mouse chromosome 2., J Peters, L D. Siracusa, D Pomp, A R. Zuberi, D Church, R Koratkar, and C M. Abbott

Four paralogous protein 4.1 genes map to distinct chromosomes in mouse and human., L L. Peters, H U. Weier, L D. Walensky, S H. Snyder, M Parra, N Mohandas, and J G. Conboy