Faculty Research 1990 - 1999
Submissions from 1995
New seizure frequency QTL and the complex genetics of epilepsy in EL mice., W N. Frankel, A Valenzuela, C M. Lutz, E W. Johnson, W F. Dietrich, and J M. Coffin
Mouse mammary tumor viruses with functional superantigen genes are selected during in vivo infection., T V. Golovkina, J P. Dudley, A B. Jaffe, and S R. Ross
Software availability [letter; comment], N Goodman, E S. Lander, and Soltz R. Oberai
Brain spectrin: of mice and men., S R. Goodman, W E. Zimmer, M B. Clark, I S. Zagon, J E. Barker, and M L. Bloom
Improved engraftment of human spleen cells in NOD/LtSz-scid/scid mice as compared with C.B-17-scid/scid mice., D L. Greiner, L D. Shultz, J Yates, M C. Appel, G Perdrizet, R M. Hesselton, I Schweitzer, W G. Beamer, K L. Shultz, S C. Pelsue, Jean H. Leif, and Thiruchandurai V. Rajan
The genes coding for alpha and beta catenin (Catna1 and Catnb) and plakoglobin (Jup) map to mouse chromosomes 18, 9, and 11, respectively., J L. Guenet, Chazottes D. Simon, M Ringwald, and R Kemler
Biotherapy for xenografted human central nervous system leukemia in mice with severe combined immunodeficiency using B43 (anti-CD19)-pokeweed antiviral protein immunotoxin., R Gunther, L M. Chelstrom, Ahlgren L. Tuel, J Simon, D E. Myers, and F M. Uckun
Papillomavirus infection in raccoons (Procyon lotor)., A N. Hamir, G Moser, A B. Jenson, J P. Sundberg, C Hanlon, and C E. Rupprecht
Analysis of the mechanism(s) of metaphase I arrest in maturing mouse oocytes., A Hampl and J J. Eppig
Translational regulation of the gradual increase in histone H1 kinase activity in maturing mouse oocytes., A Hampl and J J. Eppig
Allele capture by selection for flanking markers: a new method for analyzing multigenic traits [editorial], D E. Harrison, T H. Roderick, and K Paigen
Mouse model for Usher syndrome: linkage mapping suggests homology to Usher type I reported at human chromosome 11p15., J R. Heckenlively, B Chang, L C. Erway, C Peng, N L. Hawes, G S. Hageman, and T H. Roderick
High levels of human peripheral blood mononuclear cell engraftment and enhanced susceptibility to human immunodeficiency virus type 1 infection in NOD/LtSz-scid/scid mice., R M. Hesselton, D L. Greiner, J P. Mordes, T V. Rajan, J L. Sullivan, and L D. Shultz
Characterization of a new antigen expressed by B and myeloid lineage cells identified by the monoclonal antibody LIP-6., K L. Holmes, L M. Lantz, J S. Lee, H G. Bedigian, and J K. Taubenberger
Immunoperoxidase detection of ophidian paramyxovirus in snake lung using a polyclonal antibody., B L. Homer, J P. Sundberg, J M. Gaskin, J Schumacher, and E R. Jacobson
Preimplantation development of mouse embryos in KSOM: augmentation by amino acids and analysis of gene expression., Y Ho, K Wigglesworth, J J. Eppig, and R M. Schultz
Mapping the mouse dactylaplasia mutation, Dac, and a gene that controls its expression, mdac., K R. Johnson, P W. Lane, Bailey P. Ward, and M T. Davisson
Genetic decreases in atrial natriuretic peptide and salt-sensitive hypertension [published erratum appears in Science 1995 Mar 24;267(5205):1753], S W. John, J H. Krege, P M. Oliver, J R. Hagaman, J B. Hodgin, S C. Pang, T G. Flynn, and O Smithies
Increased cation permeability in mutant mouse red blood cells with defective membrane skeletons., C H. Joiner, R S. Franco, M Jiang, M S. Franco, J E. Barker, and S E. Lux
The effect of relative humidity on mouse allergen levels in an environmentally controlled mouse room., R B. Jones, J B. Kacergis, M R. MacDonald, F T. McKnight, W A. Turner, J L. Ohman, and B Paigen
Long-term repopulating abilities of enriched fetal liver stem cells measured by competitive repopulation., C T. Jordan, C M. Astle, J Zawadzki, K Mackarehtschian, I R. Lemischka, and D E. Harrison
Apolipoprotein E deficiency in mice: gene replacement and prevention of atherosclerosis using adenovirus vectors., V S. Kashyap, Fojo S. Santamarina, D R. Brown, C L. Parrott, Bowden D. Applebaum, S Meyn, G Talley, B Paigen, N Maeda, and H B. Brewer
Supportive cellular elements for hepatic T cell differentiation: T cells expressing intermediate levels of the T cell receptor are cytotoxic against syngeneic hepatoma, and are lost after hepatocyte damage., Y Kawachi, K Arai, T Moroda, T Kawamura, H Umezu, M Naito, K Ohtsuka, K Hasegawa, H Takahashi-Iwanaga, and T Iwanaga
Lith1, a major gene affecting cholesterol gallstone formation among inbred strains of mice., B Khanuja, Y C. Cheah, M Hunt, P M. Nishina, D Q. Wang, H W. Chen, J T. Billheimer, M C. Carey, and B Paigen
Molecular polymorphism in the Rt6 genes of laboratory mice correlates with the allotypes of the H1 minor histocompatibility system., Nolte F. Koch, C Hollmann, M Kuhl, F Haag, M Prochazka, E Leiter, and H G. Thiele
Expression of the mitochondrial uncoupling protein gene from the aP2 gene promoter prevents genetic obesity., J Kopecky, G Clarke, S Enerback, B Spiegelman, and L P. Kozak
Male-female differences in fertility and blood pressure in ACE-deficient mice., J H. Krege, S W. John, L L. Langenbach, J B. Hodgin, J R. Hagaman, E S. Bachman, J C. Jennette, D A. O'Brien, and O Smithies
Engraftment of immune-deficient mice with primitive hematopoietic cells from beta-thalassemia and sickle cell anemia patients: implications for evaluating human gene therapy protocols., A Larochelle, J Vormoor, T Lapidot, G Sher, T Furukawa, Q Li, L D. Shultz, N F. Olivieri, G Stamatoyannopoulos, and J E. Dick
Mechanistic and developmental aspects of genetic imprinting in mammals., K E. Latham, J McGrath, and D Solter
Retroviral gene transfer into the intestinal epithelium., C Lau, H E. Soriano, F D. Ledley, M J. Finegold, J H. Wolfe, E H. Birkenmeier, and S J. Henning
A curly-tail modifier locus, mct1, on mouse chromosome 17., V A. Letts, N J. Schork, A J. Copp, M Bernfield, and W N. Frankel
A fibrillar collagen gene, Col11a1, is essential for skeletal morphogenesis [see comments], Y Li, D A. Lacerda, M L. Warman, D R. Beier, H Yoshioka, Y Ninomiya, J T. Oxford, N P. Morris, K Andrikopoulos, F Ramirez, B B. Wardell, G D. Lifferth, C Teuscher, S R. Woodward, B A. Taylor, R E. Seegmiller, and B R. Olsen
Survival of human prostate carcinoma, benign hyperplastic prostate tissues, and IL-2-activated lymphocytes in scid mice., D M. Lubaroff, M B. Cohen, L D. Schultz, and W G. Beamer
Protein characterization and targeted disruption of Grg, a mouse gene related to the groucho transcript of the Drosophila Enhancer of split complex., M Mallo, Maguire M. Gendron, M L. Harbison, and T Gridley
Possible involvement of the mouse Grg protein in transcription., M Mallo, P M. Lieberman, and T Gridley
Crosses of NOD mice with the related NON strain. A polygenic model for IDDM., Marcia A. McAleer, Peter Reifsnyder, Sheila M. Palmer, Michal Prochazka, Jennifer M. Love, James B. Copeman, Elizabeth E. Powell, Nanda R. Rodrigues, Jan-Bas Prins, David V. Serreze, Nicole H. DeLarato, Linda S. Wicker, Laurence B. Peterson, Nicholas J. Schork, John A. Todd, and Edward H. Leiter
Genetics of primary and timing effects in the mnd mouse., A Messer, J Plummer, M C. MacMillen, and W N. Frankel
Localization of the tight junction protein gene TJP1 to human chromosome 15q13, distal to the Prader-Willi/Angelman region, and to mouse chromosome 7., T K. Mohandas, X N. Chen, L B. Rowe, E H. Birkenmeier, A S. Fanning, J M. Anderson, and J R. Korenberg
Maintenance of the human malarial parasite, Plasmodium falciparum, in scid mice and transmission of gametocytes to mosquitoes., J M. Moore, N Kumar, L D. Shultz, and T V. Rajan
Cutaneous ultrastructural features of the flaky skin (fsn) mouse mutation., K Morita, M E. Hogan, L B. Nanney, L E. King, M Manabe, T T. Sun, and J P. Sundberg
A Rosetta stone of mammalian genetics., J H. Nadeau, P L. Grant, S Mankala, A H. Reiner, J E. Richardson, and J T. Eppig
Hyperproinsulinaemia in obese fat/fat mice associated with a carboxypeptidase E mutation which reduces enzyme activity., J K. Naggert, L D. Fricker, O Varlamov, P M. Nishina, Y Rouille, D F. Steiner, R J. Carroll, B J. Paigen, and E H. Leiter
Genomic analysis of the C57BL/Ks mouse strain., J K. Naggert, J L. Mu, W Frankel, D W. Bailey, and B Paigen
Chromosomal locations of major tRNA gene clusters of Xenopus laevis., S Narayanswami, J L. Doering, F J. Fokta, D S. Rosenthal, T N. Nguyen, and B A. Hamkalo
Susceptibility to vinblastine-induced aneuploidy and preferential chromosome segregation during meiosis I in Robertsonian heterozygous mice., F Pacchierotti, C Tiveron, J B. Mailhes, and M T. Davisson
Genetics of responsiveness to high-fat and high-cholesterol diets in the mouse., B Paigen
A miracle enough: the power of mice., K Paigen
Mapping of the flaky skin (fsn) mutation on distal mouse chromosome 17., S C. Pelsue, P A. Schweitzer, W G. Beamer, and L D. Shultz
The gene encoding the erythrocyte membrane skeleton protein dematin (Epb4.9) maps to mouse chromosome 14., L L. Peters, E M. Eicher, A C. Azim, and A H. Chishti
Ank3 (epithelial ankyrin), a widely distributed new member of the ankyrin gene family and the major ankyrin in kidney, is expressed in alternatively spliced forms, including forms that lack the repeat domain., L L. Peters, K M. John, F M. Lu, E M. Eicher, A Higgins, M Yialamas, L C. Turtzo, A J. Otsuka, and S E. Lux
B lymphocytes are not required for murine resistance to the human filarial parasite, Brugia malayi., T V. Rajan, L D. Shultz, J Yates, and D L. Greiner
A mouse model for Down syndrome exhibits learning and behaviour deficits [see comments], R H. Reeves, N G. Irving, T H. Moran, A Wohn, C Kitt, S S. Sisodia, C Schmidt, R T. Bronson, and M T. Davisson
Mapping the Bst mutation on mouse chromosome 16: a model for human optic atrophy., D S. Rice, R W. Williams, Bailey P. Ward, K R. Johnson, B S. Harris, M T. Davisson, and D Goldowitz
Goosecoid is not an essential component of the mouse gastrula organizer but is required for craniofacial and rib development., Perez J. Rivera, M Mallo, Maguire M. Gendron, T Gridley, and R R. Behringer
Islet-infiltrating lymphocytes from prediabetic NOD mice rapidly transfer diabetes to NOD-scid/scid mice., P W. Rohane, A Shimada, D T. Kim, C T. Edwards, B Charlton, L D. Shultz, and C G. Fathman
Regulation of the uncoupling protein gene (Ucp) by beta 1, beta 2, and beta 3-adrenergic receptor subtypes in immortalized brown adipose cell lines., E M. Rohlfs, K W. Daniel, R T. Premont, L P. Kozak, and S Collins
Treatment with growth hormone and IGF-I in growing rats increases bone mineral content but not bone mineral density., H N. Rosen, V Chen, A Cittadini, S L. Greenspan, P S. Douglas, A C. Moses, and W G. Beamer
Differentiating between orchiectomized rats and controls using measurements of trabecular bone density: a comparison among DXA, histomorphometry, and peripheral quantitative computerized tomography., H N. Rosen, S Tollin, R Balena, V L. Middlebrooks, W G. Beamer, L R. Donohue, C Rosen, A Turner, M Holick, and S L. Greenspan
Syngeneic bone marrow transplantation reduces the hearing loss associated with murine mucopolysaccharidosis type VII., M S. Sands, L C. Erway, C Vogler, W S. Sly, and E H. Birkenmeier
Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation., T N. Sato, Y Tozawa, U Deutsch, Buchholz K. Wolburg, Y Fujiwara, Maguire M. Gendron, T Gridley, H Wolburg, W Risau, and Y Qin
Positional cloning of the nude locus: genetic, physical, and transcription maps of the region and mutations in the mouse and rat., J A. Segre, J L. Nemhauser, B A. Taylor, J H. Nadeau, and E S. Lander
Emv30null NOD-scid mice. An improved host for adoptive transfer of autoimmune diabetes and growth of human lymphohematopoietic cells., D V. Serreze, E H. Leiter, M S. Hanson, S W. Christianson, L D. Shultz, R M. Hesselton, and D L. Greiner
Mapping of the Sca1 and pcd genes on mouse chromosome 13 provides evidence that they are different genes., A Servadio, A McCall, H Zoghbi, and E M. Eicher
Multiple defects in innate and adaptive immunologic function in NOD/LtSz-scid mice., L D. Shultz, P A. Schweitzer, S W. Christianson, B Gott, I B. Schweitzer, B Tennent, S McKenna, L Mobraaten, T V. Rajan, and D L. Greiner
Large scale isolation of expression vector cassette by magnetic triple helix affinity capture., S V. Sonti, M C. Griffor, T Sano, S Narayanswami, A Bose, C R. Cantor, and A P. Kausch
Strain distribution pattern for SSLP markers in the SWXJ recombinant inbred strain set: chromosomes 1 to 6., K L. Svenson, Y C. Cheah, K L. Shultz, J L. Mu, B Paigen, and W G. Beamer
Thymic epithelial cell abnormalities in (NZB x H-2u)F1 mice., Y Takeoka, K J. Whitmer, S Y. Chen, A A. Ansari, R L. Boyd, L D. Shultz, S Suehiro, and M E. Gershwin
Typing recombinant inbred mouse strains for microsatellite markers on chromosomes 10, 16, 18, 19, and X., B A. Taylor and S J. Phillips
Genetics of age-related hearing loss in mice. II. Strain differences and effects of caloric restriction on cochlear pathology and evoked response thresholds., J F. Willott, L C. Erway, J R. Archer, and D E. Harrison
A functional p53-responsive intronic promoter is contained within the human mdm2 gene., A Zauberman, D Flusberg, Y Haupt, Y Barak, and M Oren
Submissions from 1994
Cystic adenomatous hyperplasia of the equine allantois: a report of eight cases.
Gene regulation during neuronal and non-neuronal differentiation of NTERA2 human teratocarcinoma-derived stem cells., S L. Ackerman, B B. Knowles, and P W. Andrews
A mutation in the Ter gene causing increased susceptibility to testicular teratomas maps to mouse chromosome 18., Y Asada, D S. Varnum, W N. Frankel, and J H. Nadeau
Oral infection with Porphyromonas gingivalis and induced alveolar bone loss in immunocompetent and severe combined immunodeficient mice., P J. Baker, R T. Evans, and D C. Roopenian
Regulation of mdm2 expression by p53: alternative promoters produce transcripts with nonidentical translation potential., Y Barak, E Gottlieb, Gershon T. Juven, and M Oren
Targets for transcriptional activation by wild-type p53: endogenous retroviral LTR, immunoglobulin-like promoter, and an internal promoter of the mdm2 gene., Y Barak, A Lupo, A Zauberman, T Juven, Grinstein R. Aloni, E Gottlieb, V Rotter, and M Oren
Sl/Sld hematopoietic progenitors are deficient in situ., J E. Barker
Hematopoietic repopulation of adult mice with beta-thalassemia., J E. Barker and S T. Compton
Behavioral consequences of bone marrow transplantation in the treatment of murine mucopolysaccharidosis type VII., L Bastedo, M S. Sands, D T. Lambert, M A. Pisa, E Birkenmeier, and P L. Chang
Adrenocortical dysplasia: a mouse model system for adrenocortical insufficiency., W G. Beamer, H O. Sweet, R T. Bronson, J G. Shire, D N. Orth, and M T. Davisson
Pathology of the ear in murine mucopolysaccharidosis type VII. Morphologic correlates of hearing loss., C L. Berry, C Vogler, N J. Galvin, E H. Birkenmeier, and W S. Sly
Ileal lipid-binding protein (Illbp) gene maps to mouse chromosome 11., E H. Birkenmeier, L B. Rowe, M W. Crossman, and J I. Gordon
The murine mutation jaundiced is caused by replacement of an arginine with a stop codon in the mRNA encoding the ninth repeat of beta-spectrin., M L. Bloom, T M. Kaysser, C S. Birkenmeier, and J E. Barker
Obesity minimizes the immunopotentiation of food restriction in ob/ob mice., G A. Boissonneault and D E. Harrison
Prevention of diabetes in the NOD mouse: implications for therapeutic intervention in human disease., M A. Bowman, E H. Leiter, and M A. Atkinson
The original pink-eyed dilution mutation (p) arose in Asiatic mice: implications for the H4 minor histocompatibility antigen, Myod1 regulation and the origin of inbred strains., M H. Brilliant, A Ching, Y Nakatsu, and E M. Eicher
A frameshift mutation in the mouse alpha 1 glycine receptor gene (Glra1) results in progressive neurological symptoms and juvenile death., M S. Buckwalter, S A. Cook, M T. Davisson, W F. White, and S A. Camper
Molecular analysis of reverse mutations from nonagouti (a) to black-and-tan (a(t)) and white-bellied agouti (Aw) reveals alternative forms of agouti transcripts., S J. Bultman, M L. Klebig, E J. Michaud, H O. Sweet, M T. Davisson, and R P. Woychik
Cleavage of the epidermal growth factor receptor by a membrane-bound leupeptin-sensitive protease active in nonionic detergent lysates of senescent but not young human diploid fibroblasts., C Carlin, P D. Phillips, Frederich K. Brooks, B B. Knowles, and V J. Cristofalo
Retinal degeneration in motor neuron degeneration: a mouse model of ceroid lipofuscinosis., B Chang, R T. Bronson, N L. Hawes, T H. Roderick, C Peng, G S. Hageman, and J R. Heckenlively
New murine polymorphisms detected by random amplified polymorphic DNA (RAPD) PCR and mapped by use of recombinant inbred strains., Y C. Cheah, J H. Nadeau, S Pugh, and B Paigen
Strain distribution patterns for 50 SSLP markers in the murine AKXL recombinant inbred set., Y C. Cheah and B Paigen
A segment of the MHC class II beta chain plays a critical role in targeting class II molecules to the endocytic pathway., A V. Chervonsky, L Gordon, and A J. Sant
Acquisition of meiotic competence by denuded mouse oocytes: participation of somatic-cell product(s) and cAMP., F Chesnel, K Wigglesworth, and J J. Eppig
Brain alpha erythroid spectrin: identification, compartmentalization, and beta spectrin associations., M B. Clark, Y Ma, M L. Bloom, J E. Barker, I S. Zagon, W E. Zimmer, and S R. Goodman
Chromosomal mapping of mouse genes expressed selectively within the central nervous system., P E. Danielson, J B. Watson, D D. Gerendasy, M G. Erlander, T W. Lovenberg, L e. de, J G. Sutcliffe, and W N. Frankel
A mouse model for Fraser syndrome?, S Darling and A Gossler
Rules and guidelines for nomenclature of mouse genes. International Committee on Standardized Genetic Nomenclature for Mice., M T. Davisson
Balding: a new mutation on mouse chromosome 18 causing hair loss and immunological defects., M T. Davisson, S A. Cook, K R. Johnson, and E M. Eicher
Molecular and genetic characterization of GABP beta., la Brousse de, E H. Birkenmeier, D S. King, L B. Rowe, and S L. McKnight