Faculty Research 1990 - 1999
Submissions from 1993
Hematopoietic stem-cell defects underlying abnormal macrophage development and maturation in NOD/Lt mice: defective regulation of cytokine receptors and protein kinase C., D V. Serreze, J W. Gaedeke, and E H. Leiter
Defects in the differentiation and function of antigen presenting cells in NOD/Lt mice., D V. Serreze, H R. Gaskins, and E H. Leiter
Mutations at the murine motheaten locus are within the hematopoietic cell protein-tyrosine phosphatase (Hcph) gene., L D. Shultz, P A. Schweitzer, T V. Rajan, T Yi, J N. Ihle, R J. Matthews, M L. Thomas, and D R. Beier
Multiple mechanisms of tumorigenesis in E mu-myc transgenic mice., C L. Sidman, T M. Denial, J D. Marshall, and J B. Roths
Newly acquired peri-telomeric heterochromatin in a transgenic mouse lineage., D Simon and B B. Knowles
Epidermal dendritic cell populations in the flaky skin mutant mouse., J P. Sundberg, D Boggess, B A. Sundberg, W G. Beamer, and L D. Shultz
Severe combined immunodeficiency., J P. Sundberg and L D. Shultz
Perinatal lethality and defects in hindbrain development in mice homozygous for a targeted mutation of the zinc finger gene Krox20., P J. Swiatek and T Gridley
Immunophenotypic and ultrastructural differentiation and maturation of nonlymphoid dendritic cells in osteopetrotic (op) mice with the total absence of macrophage colony stimulating factor activity., K Takahashi, M Naito, Y Morioka, and L D. Schultz
Differentiation of dendritic cell populations in macrophage colony-stimulating factor-deficient mice homozygous for the osteopetrosis (op) mutation., K Takahashi, M Naito, L D. Shultz, S Hayashi, and S Nishikawa
A new strain congenic for the Mtv-7/Mls-1 locus of mouse chromosome 1., B A. Taylor and W N. Frankel
Encyclopedia of the mouse genome III. October 1993. Mouse chromosome 10., B A. Taylor, W N. Frankel, M Burmeister, and E Bryda
Typing recombinant inbred mouse strains for microsatellite markers., B A. Taylor and P C. Reifsnyder
The MEV mouse linkage testing stock: mapping 30 novel proviral insertions and establishment of an improved stock., B A. Taylor, L Rowe, and D A. Grieco
Identification of the mutation in murine histidinemia (his) and genetic mapping of the murine histidase locus (Hal) on chromosome 10., R G. Taylor, D Grieco, G A. Clarke, R R. McInnes, and B A. Taylor
Genetic susceptibility for C19 androgen induction of ovarian granulosa cell tumorigenesis in SWXJ strains of mice., B J. Tennent, K L. Shultz, and W G. Beamer
Air quality evaluations of animal room facilities utilized for the production of laboratory mice., W A. Turner, F T. McKnight, R B. Jones, J M. Barth, Beverly J. Paigen, J L. Ohman, and M R. MacDonald
Expansion of the CD4-, CD8- gamma delta T cell subset in the spleens of mice during non-lethal blood-stage malaria., der Heyde van, M M. Elloso, D C. Roopenian, D D. Manning, and W P. Weidanz
Resolution of blood-stage malarial infections in CD8+ cell-deficient beta 2-m0/0 mice., der Heyde van, D D. Manning, D C. Roopenian, and W P. Weidanz
Enzyme replacement with recombinant beta-glucuronidase in the newborn mucopolysaccharidosis type VII mouse., C Vogler, M Sands, A Higgins, B Levy, J Grubb, E H. Birkenmeier, and W S. Sly
3-Hydroxy-3-methylglutaryl coenzyme A lyase (HL): cloning and characterization of a mouse liver HL cDNA and subchromosomal mapping of the human and mouse HL genes., S Wang, J H. Nadeau, A Duncan, M F. Robert, G Fontaine, K Schappert, K R. Johnson, E Zietkiewicz, P Hruz, and H Miziorko
3-Hydroxy-3-methylglutaryl coenzyme A lyase (HL): cloning and characterization of a mouse liver HL cDNA and subchromosomal mapping of the human and mouse HL genes., S Wang, J H. Nadeau, A Duncan, M F. Robert, G Fontaine, K Schappert, K R. Johnson, E Zietkiewicz, P Hruz, H Miziorko, and Grant A. Mitchell
The Gus-e locus regulates estrogen repression of androgen-induced beta-glucuronidase expression in mouse kidney., G Watson, R Jaussi, D Tabron, and K Paigen
Mapping of the murine and rat Facc genes and assessment of flexed-tail as a candidate mouse homolog of Fanconi anemia group C., R Wevrick, J E. Barker, J H. Nadeau, C Szpirer, and M Buchwald
Human bone marrow and umbilical cord blood cells generate CD4+ and CD8+ single-positive T cells in murine fetal thymus organ culture., H Yeoman, R E. Gress, C V. Bare, A G. Leary, E A. Boyse, J Bard, L D. Shultz, D T. Harris, and D DeLuca
Sequence-specific DNA binding by p53: identification of target sites and lack of binding to p53 - MDM2 complexes., A Zauberman, Y Barak, N Ragimov, N Levy, and M Oren
High-resolution mapping of a minor histocompatibility antigen gene on mouse chromosome 2., A R. Zuberi and D C. Roopenian
Submissions from 1992
Mouse chromosome 4., C M. Abbott, R Blank, J T. Eppig, J M. Friedman, K E. Huppi, I Jackson, B A. Mock, J Stoye, and R Wiseman
Chromosome mapping of the rod photoreceptor cGMP phosphodiesterase beta-subunit gene in mouse and human: tight linkage to the Huntington disease region (4p16.3)., M R. Altherr, J J. Wasmuth, M F. Seldin, J H. Nadeau, W Baehr, and S J. Pittler
The alpha-subunit of the skeletal muscle sodium channel is encoded proximal to Tk-1 on mouse chromosome 11., C Ambrose, S Cheng, B Fontaine, J H. Nadeau, M MacDonald, and J F. Gusella
Enhanced binding of a 95 kDa protein to p53 in cells undergoing p53-mediated growth arrest., Y Barak and M Oren
Mls-1 is encoded by the long terminal repeat open reading frame of the mouse mammary tumor provirus Mtv-7., U Beutner, W N. Frankel, M S. Cote, J M. Coffin, and B T. Huber
Tissue- and cell-specific expression of human sn-glycerol-3-phosphate dehydrogenase in transgenic mice., E H. Birkenmeier, P C. Hoppe, K A. Lyford, and B Gwynn
Fingerprinting genomes by use of PCR with primers that encode protein motifs or contain sequences that regulate gene expression [published erratum appears in Mamm Genome 1993;4(2):133], E H. Birkenmeier, U Schneider, and S J. Thurston
Brain beta spectrin isoform 235 (Spnb-2) maps to mouse chromosome 11., M L. Bloom, B K. Lee, C S. Birkenmeier, Y Ma, W E. Zimmer, S R. Goodman, E M. Eicher, and J E. Barker
Developmental abnormalities in Steel17H mice result from a splicing defect in the steel factor cytoplasmic tail., C I. Brannan, M A. Bedell, J L. Resnick, J J. Eppig, M A. Handel, D E. Williams, S D. Lyman, P J. Donovan, N A. Jenkins, and N G. Copeland
The mouse pink-eyed unstable mutation: a DNA duplication revealed by genome scanning., M H. Brilliant, Y Gondo, and E M. Eicher
Genetic and age related models of neurodegeneration in mice: dystrophic axons., R T. Bronson, H O. Sweet, C A. Spencer, and M T. Davisson
Functional analysis of a t complex responder locus transgene in mice., D C. Bullard, C Ticknor, and J C. Schimenti
The effects of early experience on callosal development and functional lateralization in pigmented BALB/c mice., Fleming B. Bulman, P E. Wainwright, and R L. Collins
Evolution of beta-glucuronidase regulation in the genus mus., R M. Bush and K Paigen
Mox-1 and Mox-2 define a novel homeobox gene subfamily and are differentially expressed during early mesodermal patterning in mouse embryos., A F. Candia, J Hu, J Crosby, P A. Lalley, D Noden, J H. Nadeau, and C V. Wright
The mouse genome: an overview., V M. Chapman and J H. Nadeau
Use of transgenic mice to map cis-acting elements in the intestinal fatty acid binding protein gene (Fabpi) that control its cell lineage-specific and regional patterns of expression along the duodenal-colonic and crypt-villus axes of the gut epithelium., S M. Cohn, T C. Simon, K A. Roth, E H. Birkenmeier, and J I. Gordon
Disorganization is a completely dominant gain-of-function mouse mutation causing sporadic developmental defects., J L. Crosby, D S. Varnum, L L. Washburn, and J H. Nadeau
Mouse chromosome 18., M T. Davisson and K R. Johnson
Expression pattern of Motch, a mouse homolog of Drosophila Notch, suggests an important role in early postimplantation mouse development., A m. Del, D E. Smith, P J. Swiatek, Maguire M. Gendron, R J. Greenspan, A P. McMahon, and T Gridley
Defective repair of radiation-induced chromosomal damage in scid/scid mice., J E. Disney, A L. Barth, and L D. Shultz
Modulation of meiotic arrest in mouse oocytes by guanyl nucleotides and modifiers of G-proteins., S M. Downs, R Buccione, and J J. Eppig
Possible role of Abb gene in mouse resistance to EL4 metastases., O S. Egorov, Y Liu, and I K. Egorov
Screening mouse mutations for resistance to cancer metastasis., O S. Egorov, Y Liu, E E. Sargent, G I. Drizlikh, and I K. Egorov
Telomere-related markers for the pseudoautosomal region of the mouse genome., E M. Eicher, B K. Lee, L L. Washburn, D W. Hale, and T R. King
Growth and development of mammalian oocytes in vitro., J J. Eppig
Developmental capacity of mouse oocytes matured in vitro: effects of gonadotrophic stimulation, follicular origin and oocyte size., J J. Eppig, A C. Schroeder, and M J. O'Brien
Comparison of embryonic developmental competence of mouse oocytes grown with and without serum., J J. Eppig, K Wigglesowrth, and M J. O'Brien
Mouse DNA clones and probes., J T. Eppig
Tumor cell IL-6 gene expression is regulated by IL-1 alpha/beta and TNF alpha: proposed feedback mechanisms induced by the interaction of tumor cells and macrophages., R Evans, M Fong, J Fuller, S Kamdar, J Meyerhardt, and G Strassmann
Synergistic interaction of bacterial lipopolysaccharide and the monocyte-macrophage colony-stimulating factor: potential quantitative and qualitative changes in macrophage-produced cytokine bioactivity., R Evans, S J. Kamdar, T M. Duffy, and J Fuller
Cellular determinants of age-related decrements in the T-cell mitogen response of B6CBAF1 mice., K Flurkey, R A. Miller, and D E. Harrison
Low-molecular-weight iodoproteins in the congenital goiters of cog/cog mice., L Fogelfeld, G Harel, W G. Beamer, and A B. Schneider
Mating stimulates estradiol production by ovaries of the musk shrew (Suncus murinus)., J E. Fortune, J J. Eppig, and E F. Rissman
Genetic quality assurance., R R. Fox
Characterization of the endogenous nonecotropic murine leukemia viruses of NZB/B1NJ and SM/J inbred strains., W N. Frankel, B K. Lee, J P. Stoye, J M. Coffin, and E M. Eicher
Expression of intra-MHC transporter (Ham) genes and class I antigens in diabetes-susceptible NOD mice [letter], H R. Gaskins, J J. Monaco, and E H. Leiter
Beta cell expression of endogenous xenotropic retrovirus distinguishes diabetes-susceptible NOD/Lt from resistant NON/Lt mice., H R. Gaskins, M Prochazka, K Hamaguchi, D V. Serreze, and E H. Leiter
Chromosomal localization of the murine stress protein gene encoding glucose-regulated protein 78 (BiP)., H R. Gaskins, M Prochazka, and E H. Leiter
Intrathymic islet cell transplantation reduces beta-cell autoimmunity and prevents diabetes in NOD/Lt mice., I C. Gerling, D V. Serreze, S W. Christianson, and E H. Leiter
Variation in EGF-induced EGF receptor downregulation in human hepatoma-derived cell lines expressing different amounts of EGF receptor., A Gilligan, S Bushmeyer, and B B. Knowles
Transgenic mouse mammary tumor virus superantigen expression prevents viral infection., T V. Golovkina, A Chervonsky, J P. Dudley, and S R. Ross
Early mouse development., A Gossler
The molecular and genetic analysis of mouse development., A Gossler and R Balling
Animal models for immunodeficiency diseases., D L. Greiner, T V. Rajan, and L D. Shultz
Difficulties with studying accelerated aging [editorial], D E. Harrison
Evaluating functional abilities of primitive hematopoietic stem cell populations., D E. Harrison
The same exhaustible multilineage precursor produces both myeloid and lymphoid cells as early as 3-4 weeks after marrow transplantation., D E. Harrison and R K. Zhong
Genetic linkage analysis of the murine developmental mutant velvet coat (Ve) and the distal chromosome 15 developmental genes Hox-3.1, Rar-g, Wnt-1, and Krt-2., C P. Hart, J G. Compton, S H. Langley, L Hunihan, K P. LeClair, A Zelent, T H. Roderick, and F H. Ruddle
Thymic involution in viable motheaten (me(v)) mice is associated with a loss of intrathymic precursor activity., S M. Hayes, L D. Shultz, and D L. Greiner
Dispersed repetitive elements in mouse genome analysis., G E. Herman, J H. Nadeau, and S C. Hardies
Genetic and dietary interactions in the regulation of HMG-CoA reductase gene expression., J J. Hwa, S Zollman, C H. Warden, B A. Taylor, P A. Edwards, A M. Fogelman, and A J. Lusis
Silver-enhanced radial immunodiffusion assay of plasma apolipoproteins., B Y. Ishida and B Paigen
Modulation of androgen-responsive gene expression by estrogen., R Jaussi, G Watson, and K Paigen
Genetic mapping of the murine gene and 14 related sequences encoding chromosomal protein HMG-14., K R. Johnson, S A. Cook, M Bustin, and M T. Davisson
Chromosomal localization of the murine gene and two related sequences encoding high-mobility-group I and Y proteins., K R. Johnson, S A. Cook, and M T. Davisson
A multipoint genetic linkage map of mouse chromosome 18., K R. Johnson and M T. Davisson
Genetic mapping of a new homeobox gene to mouse chromosome 7., K R. Johnson, S Lu, M T. Murtha, F H. Ruddle, and M T. Davisson
Five mutations at the PAH locus account for almost 90% of PKU mutations in French-Canadians from eastern Quebec., S W. John, R Rozen, R Laframboise, C Laberge, and C R. Scriver
In vitro and in vivo correlations for I65T and M1V mutations at the phenylalanine hydroxylase locus., S W. John, C R. Scriver, R Laframboise, and R Rozen
Localization of insulin-2 (Ins-2) and the obesity mutant tubby (tub) to distinct regions of mouse chromosome 7., J M. Jones, M H. Meisler, M F. Seldin, B K. Lee, and E M. Eicher
Modifications of the guanidine hydrochloride procedure for the extraction of RNA: isolation from a variety of tissues and adherent/nonadherent cell types., S J. Kamdar and R Evans
Linkage, but not gene order, of homologous loci, including alpha-L-iduronidase (Idua), is conserved in the Huntington disease region of the mouse and human genomes., T Koizumi, M MacDonald, M B:ucan, J J. Hopwood, C P. Morris, H S. Scott, J F. Gusella, and J H. Nadeau
Enhancer trap integrations in mouse embryonic stem cells give rise to staining patterns in chimaeric embryos with a high frequency and detect endogenous genes., R Korn, M Schoor, H Neuhaus, U Henseling, R Soininen, J Zachgo, and A Gossler
Adrenergic regulation of the mitochondrial uncoupling protein gene in brown fat tumor cells., U C. Kozak, W Held, D Kreutter, and L P. Kozak
Rostral cerebellar malformation, (rcm): a new recessive mutation on chromosome 3 of the mouse., P W. Lane, R T. Bronson, and C A. Spencer
Antigen presenting cells and the immunogenetics of autoimmune diabetes in NOD mice., E H. Leiter and D V. Serreze
Polygenic influences on the length of oestrous cycles in inbred mice involve MHC alleles., S P. Lerner, C P. Anderson, D E. Harrison, R L. Walford, and C E. Finch
Genetic and molecular analysis of recessive alleles at the pink-eyed dilution (p) locus of the mouse., M F. Lyon, T R. King, Y Gondo, J M. Gardner, Y Nakatsu, E M. Eicher, and M H. Brilliant
Time and space clusters of the French-Canadian M1V phenylketonuria mutation in France., S Lyonnet, D Melle, M de Braekeleer, R Laframboise, F Rey, S W John, M Berthelon, J Berthelot, H Journel, and B Le Marec
Structure of the murine tissue factor gene. Chromosome location and conservation of regulatory elements in the promoter., N Mackman, S Imes, W H. Maske, B A. Taylor, A J. Lusis, and T A. Drake