Follow

Submissions from 2018

Link

Lithium induces aerobic glycolysis and glutaminolysis in collecting duct principal cells., Mohammad Alsady, Theun de Groot, Marleen L A Kortenoeven, Claudia Carmone, Kim Neijman, Melissa Bekkenkamp-Grovenstein, Udo Engelke, Ron Wevers, Ruben Baumgarten, Ron Korstanje, and Peter M T Deen

PDF

NKX2-5 regulates human cardiomyogenesis via a HEY2 dependent transcriptional network., David J Anderson, David I Kaplan, Katrina M Bell, Katerina Koutsis, John M Haynes, Richard J Mills, Dean G Phelan, Elizabeth L Qian, Ana Rita Leitoguinho, Deevina Arasaratnam, Tanya Labonne, Elizabeth S Ng, Richard P Davis, Simona Casini, Robert Passier, James E Hudson, Enzo R Porrello, Mauro W Costa, Arash Rafii, Clare L Curl, Lea M Delbridge, Richard P Harvey, Alicia Oshlack, Michael M Cheung, Christine L Mummery, Stephen Petrou, Andrew G Elefanty, Edouard G Stanley, and David A Elliott

Link

Capturing Totipotent Stem Cells., Christopher L. Baker and Martin F Pera

Link

Immunotherapy: Cancer vaccines on the move., Jacques Banchereau and Karolina Palucka

PDF

Reconstructing the molecular life history of gliomas., Floris P Barthel, Pieter Wesseling, and Roel G W Verhaak

PDF

FusorSV: an algorithm for optimally combining data from multiple structural variation detection methods., Timothy Becker, Wan-Ping Lee, Joseph Leone, Qihui Zhu, Chengsheng Zhang, Silvia Liu, Jack Sargent, Kritika Shanker, Adam Mil-Homens, Eliza Cerveira, Mallory Ryan, Jane Cha, Fabio C P Navarro, Timur Galeev, Mark Gerstein, Ryan E Mills, Dong-Guk Shin, Charles Lee, and Ankit Malhotra

PDF

Disease Ontology: improving and unifying disease annotations across species., Susan M. Bello, Mary Shimoyama, Elvira Mitraka, Stanley J F Laulederkind, Cynthia Smith, Janan T. Eppig, and Lynn M Schriml

Link

Role of metabolic spatiotemporal dynamics in regulating biofilm colony expansion., Federico Bocci, Yoko Suzuki, Mingyang Lu, and José N Onuchic

PDF

Mouse Phenome Database: an integrative database and analysis suite for curated empirical phenotype data from laboratory mice., Molly A. Bogue, Stephen C. Grubb, David O Walton, Vivek M. Philip, Georgi Kolishovski, Timothy M Stearns, Matthew H Dunn, Daniel A Skelly, Beena Kadakkuzha, Gregg TeHennepe, Govindarajan Kunde-Ramamoorthy, and Elissa J Chesler

PDF

α Cell Function and Gene Expression Are Compromised in Type 1 Diabetes., Marcela Brissova, Rachana Haliyur, Diane Saunders, Shristi Shrestha, Chunhua Dai, David M Blodgett, Rita Bottino, Martha Campbell-Thompson, Radhika Aramandla, Gregory Poffenberger, Jill Lindner, Fong Cheng Pan, Matthias G von Herrath, Dale L Greiner, Leonard D. Shultz, May Sanyoura, Louis H Philipson, Mark Atkinson, David M Harlan, Shawn E Levy, Nripesh Prasad, Roland Stein, and Alvin C Powers

PDF

Frataxin-deficient neurons and mice models of Friedreich ataxia are improved by TAT-MTScs-FXN treatment., Elena Britti, Fabien Delaspre, Anat Feldman, Melissa Osborne, Hagar Greif, Jordi Tamarit, and Joaquim Ros

Link

In vitro and in vivo studies of the ALS-FTLD protein CHCHD10 reveal novel mitochondrial topology and protein interactions., S R Burstein, F Valsecchi, H Kawamata, M Bourens, R Zeng, Aamir Zuberi, T A Milner, S M Cloonan, Cathleen Lutz, A Barrientos, and G Manfredi

The "adipose tissue expandability" hypothesis: a potential mechanism for insulin resistance in obese youth., Sonia Caprio, Bridget Pierpont, and Romy Kursawe

PDF

Mutations in DNA repair genes are associated with increased neo-antigen load and activated T cell infiltration in lung adenocarcinoma., Young Kwang Chae, Jonathan F Anker, Preeti Bais, Sandeep Namburi, Francis J Giles, and Jeffrey H Chuang

PDF

JEPEGMIX2: improved gene-level joint analysis of eQTLs in cosmopolitan cohorts., Chris Chatzinakos, Donghyung Lee, Bradley T Webb, Vladimir I Vladimirov, Kenneth S Kendler, and Silviu-Alin Bacanu

Link

Relative Contributions of B Cells and Dendritic Cells from Lupus-Prone Mice to CD4, Seung-Chul Choi, Zhiwei Xu, Wei Li, Hong Yang, Derry C. Roopenian, Herbert C Morse, and Laurence Morel

Link

Force Generation via β-Cardiac Myosin, Titin, and α-Actinin Drives Cardiac Sarcomere Assembly from Cell-Matrix Adhesions., Anant Chopra, Matthew L Kutys, Kehan Zhang, William J Polacheck, Calvin C Sheng, Rebeccah J Luu, Jeroen Eyckmans, J Travis Hinson, Jonathan G Seidman, Christine E Seidman, and Christopher S Chen

Link

A multiethnic genome-wide association study of primary open-angle glaucoma identifies novel risk loci., Hélène Choquet, Seyyedhassan Paylakhi, Stephen C. Kneeland, Khanh K Thai, Thomas J Hoffmann, Jie Yin, Mark N Kvale, Yambazi Banda, Nicholas G Tolman, Pete A. Williams, Catherine Schaefer, Ronald B Melles, Neil Risch, Simon W M John, K Saidas Nair, and Eric Jorgenson

Link

Alterations in the Rho pathway contribute to Epstein-Barr virus-induced lymphomagenesis in immunosuppressed environments., Sung-Yup Cho, Chang Ohk Sung, Jeesoo Chae, Jieun Lee, Deukchae Na, Wonyoung Kang, Jinjoo Kang, Seoyeon Min, Ahra Lee, Eunhye Kwak, Jooyoung Kim, Boram Choi, Hyunsoo Kim, Jeffrey H Chuang, Hyo-Kyung Pak, Chan-Sik Park, Sanghui Park, Young Hyeh Ko, Dakeun Lee, Jin Roh, Min-Sun Cho, Seongyeol Park, Young Seok Ju, Yun-Suhk Suh, Seong-Ho Kong, Hyuk-Joon Lee, James Keck, Jacques Banchereau, Edison T Liu, Woo-Ho Kim, Hansoo Park, Han-Kwang Yang, Jong-Il Kim, and Charles Lee

PDF

Sensing the cilium, digital capture of ciliary data for comparative genomics investigations., Karen R. Christie and Judith A. Blake

Link

Intermittent Fasting Confers Protection in CNS Autoimmunity by Altering the Gut Microbiota., Francesca Cignarella, Claudia Cantoni, Laura Ghezzi, Amber Salter, Yair Dorsett, Lei Chen, Daniel S Phillips, George M. Weinstock, Luigi Fontana, Anne H Cross, Yanjiao Zhou, and Laura Piccio

PDF

Mechanistic Differences in Neuropathic Pain Modalities Revealed by Correlating Behavior with Global Expression Profiling., Enrique J Cobos, Chelsea A Nickerson, Fuying Gao, Vijayendran Chandran, Inmaculada Bravo-Caparrós, Rafael González-Cano, Priscilla Riva, Nick A Andrews, Alban Latremoliere, Corey R Seehus, Gloria Perazzoli, Francisco R Nieto, Nicole Joller, Michio W Painter, Chi Him Eddie Ma, Takao Omura, Elissa J Chesler, Daniel H Geschwind, Giovanni Coppola, Manu Rangachari, Clifford J Woolf, and Michael Costigan

Enterotypes in the landscape of gut microbial community composition., Paul I Costea, Falk Hildebrand, Arumugam Manimozhiyan, Fredrik Bäckhed, Martin J Blaser, Frederic D Bushman, Willem M de Vos, S Dusko Ehrlich, Claire M Fraser, Masahira Hattori, Curtis Huttenhower, Ian B Jeffery, Dan Knights, James D Lewis, Ruth E Ley, Howard Ochman, Paul W O'Toole, Christopher Quince, David A Relman, Fergus Shanahan, Shinichi Sunagawa, Jun Wang, George M. Weinstock, Gary D Wu, Georg Zeller, Liping Zhao, Jeroen Raes, Rob Knight, and Peer Bork

Link

Shared and organism-specific host responses to childhood diarrheal diseases revealed by whole blood transcript profiling., Hannah A DeBerg, Mussaret B Zaidi, Matthew C Altman, Prasong Khaenam, Vivian H Gersuk, Freddy D Campos, Iza Perez-Martinez, Mario Meza-Segura, Damien Chaussabel, Jacques Banchereau, Teresa Estrada-Garcia, and Peter S Linsley

Link

Discordant inheritance of chromosomal and extrachromosomal DNA elements contributes to dynamic disease evolution in glioblastoma., Ana C deCarvalho, Hoon Kim, Laila M Poisson, Mary E Winn, Claudius Mueller, David Cherba, Julie Koeman, Sahil Seth, Alexei Protopopov, Michelle Felicella, Siyuan Zheng, Asha Multani, Yongying Jiang, Jianhua Zhang, Do-Hyun Nam, Emanuel F Petricoin, Lynda Chin, Tom Mikkelsen, and Roel G W Verhaak

PDF

Exploring autophagy with Gene Ontology., Paul Denny, Marc Feuermann, David P. Hill, Ruth C Lovering, Helene Plun-Favreau, and Paola Roncaglia

PDF

Exploring autophagy with Gene Ontology., Paul Denny, Marc Feuermann, David P. Hill, Ruth C Lovering, Helene Plun-Favreau, and Paola Roncaglia

PDF

The innate immune response to ischemic injury: a multiscale modeling perspective., Elena Dimitrova, Leslie A Caromile, Reinhard Laubenbacher, and Linda H Shapiro

PDF

The polo-like kinase 1 inhibitor volasertib synergistically increases radiation efficacy in glioma stem cells., Jianwen Dong, Soon Young Park, Nghi Nguyen, Ravesanker Ezhilarasan, Emmanuel Martinez-Ledesma, Shaofang Wu, Verlene Henry, Yuji Piao, Ningyi Tiao, David Brunell, Clifford Stephan, Roel G W Verhaak, Erik Sulman, Veerakumar Balasubramaniyan, and John F de Groot

PDF

SARNAclust: Semi-automatic detection of RNA protein binding motifs from immunoprecipitation data., Ivan Dotu, Scott I Adamson, Benjamin Coleman, Cyril Fournier, Emma Ricart-Altimiras, Eduardo Eyras, and Jeffrey H Chuang

Link

Progression of whole-blood transcriptional signatures from interferon-induced to neutrophil-associated patterns in severe influenza., Jake Dunning, Simon Blankley, Long T Hoang, Mike Cox, Christine M Graham, Philip L James, Chloe I Bloom, Damien Chaussabel, Jacques Banchereau, Stephen J Brett, MOSAIC Investigators, Miriam F Moffatt, Anne O'Garra, and Peter J M Openshaw

Gene Therapy with an Adeno-Associated Viral Vector Expressing Human Interleukin-2 Alters Immune System Homeostasis in Humanized Mice., Philip A Durost, Ken-Edwin Aryee, Fatima Manzoor, Roland M Tisch, Christian Mueller, Agata Jurczyk, Leonard D. Shultz, and Michael A Brehm

Human dental stem cell derived transgene-free iPSCs generate functional neurons via embryoid body-mediated and direct induction methods., Ikbale El Ayachi, Jun Zhang, Xiao-Ying Zou, Dong Li, Zongdong Yu, Wei Wei, Kristen M S O'Connell, and George T-J Huang

Reproduction: Oocytes Call, Granulosa Cells Connect., John J. Eppig

Link

Antitumor Activity of Osimertinib, an Irreversible Mutant-Selective EGFR Tyrosine Kinase Inhibitor, in NSCLC Harboring EGFR Exon 20 Insertions., Nicolas Floc'h, Matthew J Martin, Jonathan W Riess, Jonathan P Orme, Anna D Staniszewska, Ludovic Ménard, Maria Emanuela Cuomo, Daniel J O'Neill, Richard A Ward, M Raymond V Finlay, Darren McKerrecher, Mingshan Cheng, Daniel P Vang, Rebekah A Burich, James G. Keck, David R Gandara, Philip C Mack, and Darren A E Cross

PDF

Gearing up to handle the mosaic nature of life in the quest for orthologs., Kristoffer Forslund, Cecile Pereira, Salvador Capella-Gutierrez, Alan Sousa da Silva, Adrian Altenhoff, Jaime Huerta-Cepas, Matthieu Muffato, Mateus Patricio, Klaas Vandepoele, Ingo Ebersberger, Judith A. Blake, Jesualdo Tomás Fernández Breis, The Quest for Orthologs Consortium, Brigitte Boeckmann, Toni Gabaldón, Erik Sonnhammer, Christophe Dessimoz, and Suzanna Lewis

PDF

Profiling of epidermal lipids in a mouse model of dermatitis: Identification of potential biomarkers., Jackeline Franco, Christina Ferreira, Tiago J Paschoal Sobreira, John P Sundberg, and Harm HogenEsch

PDF

Identifying noncoding risk variants using disease-relevant gene regulatory networks., Long Gao, Yasin Uzun, Peng Gao, Bing He, Xiaoke Ma, Jiahui Wang, Shizhong Han, and Kai Tan

Link

Homologous Recombination DNA Repair Pathway Disruption and Retinoblastoma Protein Loss Are Associated with Exceptional Survival in High-Grade Serous Ovarian Cancer., Dale W Garsed, Kathryn Alsop, Sian Fereday, Catherine Emmanuel, Catherine J Kennedy, Dariush Etemadmoghadam, Bo Gao, Val Gebski, Valérie Garès, Elizabeth L Christie, Maartje C A Wouters, Katy Milne, Joshy George, Ann-Marie Patch, Jason Li, Gisela Mir Arnau, Timothy Semple, Sreeja R Gadipally, Yoke-Eng Chiew, Joy Hendley, Thomas Mikeska, Giada V Zapparoli, Kaushalya Amarasinghe, Sean M Grimmond, John V Pearson, Nicola Waddell, Jillian Hung, Colin J R Stewart, Raghwa Sharma, Prue E Allan, Peter F Rambau, Orla McNally, Linda Mileshkin, Anne Hamilton, Sumitra Ananda, Marisa Grossi, Paul A Cohen, Yee C Leung, Robert M Rome, Philip Beale, Penny Blomfield, Michael Friedlander, Alison Brand, Alexander Dobrovic, Martin Köbel, Paul Harnett, Brad H Nelson, David D L Bowtell, and Anna deFazio

Genetic background influences susceptibility to chemotherapy-induced hematotoxicity., Daniel M. Gatti, S N Weber, N C Goodwin, F Lammert, and Gary A Churchill

Link

Method of derivation and differentiation of mouse embryonic stem cells generating synchronous neuronal networks., Elena V Gazina, Emma Morrisroe, Gunarathna D C Mendis, Anna E Michalska, Joseph Chen, Christian M Nefzger, Benjamin N Rollo, Christopher A Reid, Martin Pera, and Steven Petrou

Link

Culture-independent analysis of liver abscess using nanopore sequencing., Liang Gong, Yao-Ting Huang, Chee-Hong Wong, Wen-Cheng Chao, Zong-Yen Wu, Chia-Lin Wei, and Po-Yu Liu

Link

Picky comprehensively detects high-resolution structural variants in nanopore long reads., Liang Gong, Chee-Hong Wong, Wei-Chung Cheng, Harianto Tjong, Francesca Menghi, Chew Yee Ngan, Edison T Liu, and Chia-Lin Wei

PDF

A human endothelial cell-based recycling assay for screening of FcRn targeted molecules., Algirdas Grevys, Jeannette Nilsen, Kine M K Sand, Muluneh B Daba, Inger Øynebråten, Malin Bern, Martin B McAdam, Stian Foss, Tilman Schlothauer, Terje E Michaelsen, Gregory J. Christianson, Derry C. Roopenian, Richard S Blumberg, Inger Sandlie, and Jan Terje Andersen

PDF

Oocyte stage-specific effects of MTOR determine granulosa cell fate and oocyte quality in mice., Jing Guo, Teng Zhang, Yueshuai Guo, Tao Sun, Hui Li, Xiaoyun Zhang, Hong Yin, Guangyi Cao, Yaoxue Yin, Hao Wang, Lanying Shi, Xuejiang Guo, Jiahao Sha, John J. Eppig, and You-Qiang Su

PDF

Jnk2 deficiency increases the rate of glaucomatous neurodegeneration in ocular hypertensive DBA/2J mice., Jeffrey M. Harder, Pete A. Williams, Ileana Soto, Nicole E Foxworth, Kimberly A Fernandes, Nelson F Freeburg, Richard T Libby, and Simon W M John

PDF

Genomic Profiling of Two Histologically Distinct Rare Urothelial Cancers in a Clinical Setting to Identify Potential Therapeutic Options for Treatment and Management of Disease., Andrew N Hesse, William Fabricius, Christian A Thomas, Ramesh Gaindh, Robert Christman, Pavalan Selvam, Matthew Prego, Gregory Lewis, Jasmina Uvalic, Daniel Bergeron, Shelbi Burns, Bridgette Sisson, Kevin Kelly, Jens Rueter, and Honey V Reddi

Link

Meta-analysis of the lung microbiota in pulmonary tuberculosis., Bo-Young Hong, Joseph N Paulson, O Colin Stine, George M. Weinstock, and Jorge L Cervantes

PDF

ADAM17 is essential for ectodomain shedding of the EGF-receptor ligand amphiregulin., Vishnu Hosur, Michelle L Farley, Lisa M. Burzenski, Leonard D. Shultz, and Michael V. Wiles

Genetic Models of Macrophage Depletion., Li Hua, Jiayuan Shi, Leonard D. Shultz, and Guangwen Ren

PDF

RACIPE: a computational tool for modeling gene regulatory circuits using randomization., Bin Huang, Dongya Jia, Jingchen Feng, Herbert Levine, José N Onuchic, and Mingyang Lu

PDF

Integrative annotation and knowledge discovery of kinase post-translational modifications and cancer-associated mutations through federated protein ontologies and resources., Liang-Chin Huang, Karen E Ross, Timothy R Baffi, Harold J. Drabkin, Krzysztof J Kochut, Zheng Ruan, Peter D'Eustachio, Daniel McSkimming, Cecilia Arighi, Chuming Chen, Darren A Natale, Cynthia Smith, Pascale Gaudet, Alexandra C Newton, Cathy Wu, and Natarajan Kannan

Link

Nuclear localization of EIF4G3 suggests a role for the XY body in translational regulation during spermatogenesis in mice., Jianjun Hu, Fengyun Sun, and Mary Ann Handel

PDF

TumorFusions: an integrative resource for cancer-associated transcript fusions., Xin Hu, Qianghu Wang, Ming Tang, Floris P Barthel, Samirkumar B Amin, Kosuke Yoshihara, Frederick M Lang, Emmanuel Martinez-Ledesma, Soo Hyun Lee, Siyuan Zheng, and Roel G W Verhaak

Link

Deletion of a Long-Range, Kenneth R. Johnson, Leona H. Gagnon, Cong Tian, Chantal M. Longo-Guess, Benjamin E. Low, Michael V. Wiles, and Amy E Kiernan

Link

Deletion of a Long-Range Dlx5 Enhancer Disrupts Inner Ear Development in Mice., Kenneth R. Johnson, Leona H. Gagnon, Cong Tian, Chantal M. Longo-Guess, Benjamin E. Low, Michael V. Wiles, and Amy E Kiernan

Link

Reproducibility and replicability of rodent phenotyping in preclinical studies., Neri Kafkafi, Joseph Agassi, Elissa J Chesler, John C Crabbe, Wim E Crusio, David Eilam, Robert Gerlai, Ilan Golani, Alex Gomez-Marin, Ruth Heller, Fuad Iraqi, Iman Jaljuli, Natasha A Karp, Hugh Morgan, George Nicholson, Donald W Pfaff, S Helene Richter, Philip B Stark, Oliver Stiedl, Victoria Stodden, Lisa M Tarantino, Valter Tucci, William Valdar, Robert W Williams, Hanno Würbel, and Yoav Benjamini

Link

Genetic Fine-Mapping and Identification of Candidate Genes and Variants for Adiposity Traits in Outbred Rats., Gregory R Keele, Jeremy W Prokop, Hong He, Katie Holl, John Littrell, Aaron Deal, Sanja Francic, Leilei Cui, Daniel M. Gatti, Karl W Broman, Michael Tschannen, Shirng-Wern Tsaih, Maie Zagloul, Yunjung Kim, Brittany Baur, Joseph Fox, Melanie Robinson, Shawn Levy, Michael J Flister, Richard Mott, William Valdar, and Leah C Solberg Woods

Link

Genetic Drivers of Pancreatic Islet Function., Mark P Keller, Daniel M. Gatti, Kathryn L Schueler, Mary E Rabaglia, Donnie S Stapleton, Petr Simecek, Matthew J Vincent, Sadie Allen, Aimee Teo Broman, Rhonda Bacher, Christina Kendziorski, Karl W Broman, Brian S Yandell, Gary A Churchill, and Alan D Attie

Evaluation of exome filtering techniques for the analysis of clinically relevant genes., Kristin D Kernohan, Taila Hartley, Najmeh Alirezaie, Care4Rare Canada Consortium, Peter N Robinson, David A Dyment, and Kym M Boycott

Link

Transcriptional profiling of murine osteoblast differentiation based on RNA-seq expression analyses., Layal Abo Khayal, Johannes Grünhagen, Ivo Provazník, Stefan Mundlos, Uwe Kornak, Peter N Robinson, and Claus-Eric Ott

Link

Characterization of glycosylphosphatidylinositol biosynthesis defects by clinical features, flow cytometry, and automated image analysis., Alexej Knaus, Jean Tori Pantel, Manuela Pendziwiat, Nurulhuda Hajjir, Max Zhao, Tzung-Chien Hsieh, Max Schubach, Yaron Gurovich, Nicole Fleischer, Marten Jäger, Sebastian Köhler, Hiltrud Muhle, Christian Korff, Rikke S Møller, Allan Bayat, Patrick Calvas, Nicolas Chassaing, Hannah Warren, Steven Skinner, Raymond Louie, Christina Evers, Marc Bohn, Hans-Jürgen Christen, Myrthe van den Born, Ewa Obersztyn, Agnieszka Charzewska, Milda Endziniene, Fanny Kortüm, Natasha Brown, Peter N Robinson, Helenius J Schelhaas, Yvonne Weber, Ingo Helbig, Stefan Mundlos, Denise Horn, and Peter M Krawitz

The Impact of Adherens and Tight Junctions on Physiological Function and Pathological Changes in the Retina., Yang Kong, Juergen K. Naggert, and Patsy M. Nishina

Link

ELMOD1 Stimulates ARF6-GTP Hydrolysis to Stabilize Apical Structures in Developing Vestibular Hair Cells., Jocelyn F Krey, Rachel A Dumont, Philip A Wilmarth, Larry L David, Kenneth R. Johnson, and Peter G Barr-Gillespie

Serial immunological parameters in a phase II trial of exemestane and low-dose oral cyclophosphamide in advanced hormone receptor-positive breast cancer., Maryann Kwa, Xiaochun Li, Yelena Novik, Ruth Oratz, Komal Jhaveri, Jennifer Wu, Ping Gu, Marleen Meyers, Franco Muggia, James Speyer, Alyssa Iwano, Maryam Bonakdar, Lina Kozhaya, Ece Tavukcuoglu, Bahar Budan, Roy Raad, Judith D Goldberg, Derya Unutmaz, and Sylvia Adams

Link

A Common Type 2 Diabetes Risk Variant Potentiates Activity of an Evolutionarily Conserved Islet Stretch Enhancer and Increases C2CD4A and C2CD4B Expression., Ina Kycia, Brooke N Wolford, Jeroen R Huyghe, Christian Fuchsberger, Swarooparani Vadlamudi, Romy Kursawe, Ryan P Welch, Ricardo d'Oliveira Albanus, Asli Uyar, Shubham Khetan, Nathan Lawlor, Mohan Bolisetty, Anubhuti Mathur, Johanna Kuusisto, Markku Laakso, Duygu Ucar, Karen L Mohlke, Michael Boehnke, Francis S Collins, Stephen C J Parker, and Michael L. Stitzel

Mouse Genome Informatics (MGI) Is the International Resource for Information on the Laboratory Mouse., MeiYee Law and David R. Shaw

Cell Labeling with Magneto-Endosymbionts and the Dissection of the Subcellular Location, Fate, and Host Cell Interactions., Kayla R Lee, Abdul Wakeel, Papia Chakraborty, Chandler S Foote, Lauren Kajiura, Joyce C Barrozo, Andrea C Chan, Alexey V Bazarov, Ryan Spitler, Peter M Kutny, James M. Denegre, Robert A. Taft, Joachim Seemann, Bradley W Rice, Christopher H Contag, Brian K Rutt, and Caleb B Bell

Link

Alkaline ceramidase 2 is essential for the homeostasis of plasma sphingoid bases and their phosphates., Fang Li, Ruijuan Xu, Benjamin E. Low, Chih-Li Lin, Monica Garcia-Barros, Jennifer Schrandt, Izolda Mileva, Ashley Snider, Catherine K Luo, Xian-Cheng Jiang, Ming-Song Li, Yusuf A Hannun, Lina M Obeid, Michael V. Wiles, and Cungui Mao

Link

Digestion-ligation-only Hi-C is an efficient and cost-effective method for chromosome conformation capture., Da Lin, Ping Hong, Siheng Zhang, Weize Xu, Muhammad Jamal, Keji Yan, Yingying Lei, Liang Li, Yijun Ruan, Zhen F Fu, Guoliang Li, and Gang Cao

Link

Image-guided photo-therapeutic nanoporphyrin synergized HSP90 inhibitor in patient-derived xenograft bladder cancer model., Qilai Long, Tzu-Yin Lin, Yee Huang, Xiaocen Li, Ai-Hong Ma, Hongyong Zhang, Randy Carney, Susan Airhart, Kit S Lam, Ralph W deVere White, Chong-Xian Pan, and Yuanpei Li

PDF

Improving Interpretation of Cardiac Phenotypes and Enhancing Discovery With Expanded Knowledge in the Gene Ontology., Ruth C Lovering, Paola Roncaglia, Douglas G Howe, Stanley J F Laulederkind, Varsha K Khodiyar, Tanya Z Berardini, Susan Tweedie, Rebecca E Foulger, David Osumi-Sutherland, Nancy H Campbell, Rachael P Huntley, Philippa J Talmud, Judith A. Blake, Ross Breckenridge, Paul R Riley, Pier D Lambiase, Perry M Elliott, Lucie Clapp, Andrew Tinker, and David P. Hill

PDF

Triple Vectors Expand AAV Transfer Capacity in the Retina., Andrea Maddalena, Patrizia Tornabene, Paola Tiberi, Renato Minopoli, Anna Manfredi, Margherita Mutarelli, Settimio Rossi, Francesca Simonelli, Juergen K. Naggert, Davide Cacchiarelli, and Alberto Auricchio

Link

Pan-cancer genome and transcriptome analyses of 1,699 paediatric leukaemias and solid tumours., Xiaotu Ma, Yu Liu, Yanling Liu, Ludmil B Alexandrov, Michael N Edmonson, Charles Gawad, Xin Zhou, Yongjin Li, Michael C Rusch, John Easton, Robert Huether, Veronica Gonzalez-Pena, Mark R Wilkinson, Leandro C Hermida, Sean Davis, Edgar Sioson, Stanley Pounds, Xueyuan Cao, Rhonda E Ries, Zhaoming Wang, Xiang Chen, Li Dong, Sharon J Diskin, Malcolm A Smith, Jaime M Guidry Auvil, Paul S Meltzer, Ching C Lau, Elizabeth J Perlman, John M Maris, Soheil Meshinchi, Stephen P Hunger, Daniela S Gerhard, and Jinghui Zhang

Link

Dynamic changes in Sox2 spatio-temporal expression promote the second cell fate decision through, Tapan Kumar Mistri, Wibowo Arindrarto, Wei Ping Ng, Choayang Wang, Leng Hiong Lim, Lili Sun, Ian Chambers, Thorsten Wohland, and Paul Robson

PDF

Acclimation and Institutionalization of the Mouse Microbiota Following Transportation., Dan R Montonye, Aaron C Ericsson, Susheel B Busi, Cathleen Lutz, Keegan Wardwell, and Craig L Franklin

PDF

Aberrant GlyRS-HDAC6 interaction linked to axonal transport deficits in Charcot-Marie-Tooth neuropathy., Zhongying Mo, Xiaobei Zhao, Huaqing Liu, Qinghua Hu, Xu-Qiao Chen, Jessica Pham, Na Wei, Ze Liu, Jiadong Zhou, Robert W. Burgess, Samuel L Pfaff, C Thomas Caskey, Chengbiao Wu, Ge Bai, and Xiang-Lei Yang

PDF

The Role of Ceramide Synthases in the Pathogenicity of Cryptococcus neoformans., Mansa A Munshi, Justin M Gardin, Ashutosh Singh, Chiara Luberto, Robert Rieger, Tejas Bouklas, Bettina C Fries, and Maurizio Del Poeta

PDF

The evolutionary pattern of mutations in glioblastoma reveals therapy-mediated selection., Andrea M Muscat, Nicholas C Wong, Katharine J Drummond, Elizabeth M Algar, Mustafa Khasraw, Roel G W Verhaak, Kathryn Field, Mark A Rosenthal, and David M Ashley

PDF

A commensal strain of Staphylococcus epidermidis protects against skin neoplasia., Teruaki Nakatsuji, Tiffany H Chen, Anna M Butcher, Lynnie L Trzoss, Sang-Jip Nam, Karina T Shirakawa, Wei Zhou, Julia Oh, Michael Otto, William Fenical, and Richard L Gallo

Link

Animal models for evaluation of albumin-based therapeutics, Jeannette Nilsen, Inger Sandlie, Derry C. Roopenian, and Jan Terje Andersen

Link

Response to "Unexpected mutations after CRISPR-Cas9 editing in vivo"., Lauryl M J Nutter, Jason D Heaney, K C Kent Lloyd, Stephen A. Murray, John R Seavitt, William C Skarnes, Lydia Teboul, Steve D M Brown, and Mark Moore

PDF

Transcriptional regulatory control of mammalian nephron progenitors revealed by multi-factor cistromic analysis and genetic studies., Lori L O'Brien, Qiuyu Guo, Emad Bahrami-Samani, Joo-Seop Park, Sean M Hasso, Young-Jin Lee, Alan Fang, Albert D Kim, Jinjin Guo, Trudy M Hong, Kevin A Peterson, Scott Lozanoff, Ramya Raviram, Bing Ren, Ben Fogelgren, Andrew D Smith, Anton Valouev, and Andrew P McMahon

PDF

Activation of Serine One-Carbon Metabolism by Calcineurin Aβ1 Reduces Myocardial Hypertrophy and Improves Ventricular Function., Laura Padrón-Barthe, María Villalba-Orero, Jesús M Gómez-Salinero, Rebeca Acín-Pérez, Sara Cogliati, Marina López-Olañeta, Paula Ortiz-Sánchez, Elena Bonzón-Kulichenko, Jesús Vázquez, Pablo García-Pavía, Nadia Rosenthal, José Antonio Enríquez, and Enrique Lara-Pezzi

Link

PRDM9 and Its Role in Genetic Recombination., Kenneth Paigen and Petko M. Petkov

PDF

Müller glia-derived PRSS56 is required to sustain ocular axial growth and prevent refractive error., Seyyedhassan Paylakhi, Cassandre Labelle-Dumais, Nicholas G Tolman, Michael A Sellarole, Yusef Seymens, Joseph Saunders, Hesham Lakosha, Wilhelmine N de Vries, Andrew C Orr, Piotr Topilko, Simon W M John, and K Saidas Nair

PDF

Developmental constraint through negative pleiotropy in the zygomatic arch., Christopher J Percival, Rebecca Green, Charles C Roseman, Daniel M. Gatti, Judy Morgan, Stephen A. Murray, Leah Rae Donahue, Jessica M Mayeux, K Michael Pollard, Kunjie Hua, Daniel Pomp, Ralph Marcucio, and Benedikt Hallgrímsson

Link

Integrative Personal Omics Profiles during Periods of Weight Gain and Loss., Brian D Piening, Wenyu Zhou, Kévin Contrepois, Hannes Röst, Gucci Jijuan Gu Urban, Tejaswini Mishra, Blake M Hanson, Eddy J Bautista, Shana Leopold, Christine Y Yeh, Daniel Spakowicz, Imon Banerjee, Cynthia Chen, Kimberly Kukurba, Dalia Perelman, Colleen Craig, Elizabeth Colbert, Denis Salins, Shannon Rego, Sunjae Lee, Cheng Zhang, Jessica Wheeler, M Reza Sailani, Liang Liang, Charles Abbott, Mark Gerstein, Adil Mardinoglu, Ulf Smith, Daniel L Rubin, Sharon Pitteri, Erica Sodergren Weinstock, Tracey L McLaughlin, George M. Weinstock, and Michael P Snyder

PDF

Consensus coding sequence (CCDS) database: a standardized set of human and mouse protein-coding regions supported by expert curation., Shashikant Pujar, Nuala A O'Leary, Catherine M Farrell, Jane E Loveland, Jonathan M Mudge, Craig Wallin, Carlos G Girón, Mark Diekhans, If Barnes, Ruth Bennett, Andrew E Berry, Eric Cox, Claire Davidson, Tamara Goldfarb, Jose M Gonzalez, Toby Hunt, John Jackson, Vinita Joardar, Mike P Kay, Vamsi K Kodali, Fergal J Martin, Monica McAndrews, Kelly M McGarvey, Michael Murphy, Bhanu Rajput, Sanjida H Rangwala, Lillian D Riddick, Ruth L Seal, Marie-Marthe Suner, David Webb, Sophia Zhu, Bronwen L Aken, Elspeth A Bruford, Carol J Bult, Adam Frankish, Terence Murphy, and Kim D Pruitt

PDF

Functional Redundancy of DICER Cofactors TARBP2 and PRKRA During Murine Embryogenesis Does Not Involve miRNA Biogenesis., Sri Ramulu N Pullagura, F William Buaas, Nichelle Gray, Lindsey C Krening, Anuj Srivastava, and Robert E Braun

Improved Murine MHC-Deficient HLA Transgenic NOD Mouse Models for Type 1 Diabetes Therapy Development., Jeremy Racine, Isabel Stewart, Jeremy Ratiu, Gregory J. Christianson, Emily Lowell, Kelsay Helm, Jennifer Allocco, Richard S. Maser, Yi-Guang Chen, Cathleen Lutz, Derry C. Roopenian, Jennifer Schloss, Teresa P DiLorenzo, and David V. Serreze

Link

Cardioprotective effects of dietary rapamycin on adult female C57BLKS/J-Lepr, Peter C. Reifsnyder, Sergey Ryzhov, Kevin Flurkey, Rea P Anunciado-Koza, Ian Mills, David E Harrison, and Robert A Koza

An Analysis of the Epidemic of Klebsiella pneumoniae Carbapenemase-Producing K. pneumoniae: Convergence of Two Evolutionary Mechanisms Creates the "Perfect Storm"., Laura J Rojas, George M. Weinstock, Elsa De La Cadena, Lorena Diaz, Rafael Rios, Blake M Hanson, Joseph S Brown, Purva Vats, Daniel S Phillips, Hoan Nguyen, Kristine M Hujer, Adriana Correa, Mark D Adams, Federico Perez, Erica Sodergren Weinstock, Apurva Narechania, Paul J Planet, Maria V Villegas, Robert A Bonomo, and Cesar A Arias

PDF

Differential human gut microbiome assemblages during soil-transmitted helminth infections in Indonesia and Liberia., Bruce A Rosa, Taniawati Supali, Lincoln Gankpala, Yenny Djuardi, Erliyani Sartono, Yanjiao Zhou, Kerstin Fischer, John Martin, Rahul Tyagi, Fatorma K Bolay, Peter U Fischer, Maria Yazdanbakhsh, and Makedonka Mitreva

Screening Gene Knockout Mice for Variation in Bone Mass: Analysis by μCT and Histomorphometry., David W Rowe, Douglas J Adams, Seung-Hyun Hong, Caibin Zhang, Dong-Guk Shin, C Renata Rydzik, Li Chen, Zhihua Wu, Gaven Garland, Dana A Godfrey, John P Sundberg, and Cheryl Ackert-Bicknell

Link

Identification of genetic elements in metabolism by high-throughput mouse phenotyping., Jan Rozman, Birgit Rathkolb, Manuela A Oestereicher, Christine Schütt, Aakash Chavan Ravindranath, Stefanie Leuchtenberger, Sapna Sharma, Martin Kistler, Monja Willershäuser, Robert Brommage, Terrence F Meehan, Jeremy Mason, Hamed Haselimashhadi, Tertius Hough, Ann-Marie Mallon, Sara Wells, Luis Santos, Christopher J Lelliott, Jacqueline K White, Tania Sorg, Marie-France Champy, Lynette R Bower, Corey L Reynolds, Ann M Flenniken, Stephen A. Murray, Lauryl M J Nutter, Karen L. Svenson, David West, Glauco P Tocchini-Valentini, Arthur L Beaudet, Fatima Bosch, Robert E Braun, Michael S Dobbie, Xiang Gao, Yann Herault, Ala Moshiri, Bret A Moore, K C Kent Lloyd, Colin McKerlie, Hiroshi Masuya, Nobuhiko Tanaka, Paul Flicek, Helen E Parkinson, Radislav Sedlacek, Je Kyung Seong, Chi-Kuang Leo Wang, Mark Moore, Steve D Brown, Matthias H Tschöp, Wolfgang Wurst, Martin Klingenspor, Eckhard Wolf, Johannes Beckers, Fausto Machicao, Andreas Peter, Harald Staiger, Hans-Ulrich Häring, Harald Grallert, Monica Campillos, Holger Maier, Helmut Fuchs, Valerie Gailus-Durner, Thomas Werner, and Martin Hrabe de Angelis

Link

Androgen receptor deficiency in monocytes/macrophages does not alter adiposity or glucose homeostasis in male mice., Katya B Rubinow, Barbara Houston, Shari Wang, Leela Goodspeed, Kayoko Ogimoto, Gregory J Morton, Christopher McCarty, Robert E Braun, and Stephanie T Page

Link

Introduction to mammalian genome special issue: the combined role of genetics and environment relevant to human disease outcomes., Ivan Rusyn, Steven R Kleeberger, Kimberly A McAllister, John E French, and Karen L. Svenson

A prospective microbiome-wide association study of food sensitization and food allergy in early childhood., Jessica H Savage, Kathleen A Lee-Sarwar, Joanne Sordillo, Supinda Bunyavanich, Yanjiao Zhou, George O'Connor, Megan Sandel, Leonard B Bacharier, Robert Zeiger, Erica Sodergren Weinstock, George M. Weinstock, Diane R Gold, Scott T Weiss, and Augusto A Litonjua

PDF

Extensive Gene Amplification as a Mechanism for Piperacillin-Tazobactam Resistance in Escherichia coli., Lisa M Schechter, David P Creely, Cherilyn D Garner, Dee Shortridge, Hoan Nguyen, Lei Chen, Blake M Hanson, Erica Sodergren Weinstock, George M. Weinstock, W Michael Dunne, Alex van Belkum, and Shana R Leopold