Submissions from 2022
The Human Disease Ontology 2022 update., Lynn M Schriml, James B Munro, Mike Schor, Dustin Olley, Carrie McCracken, Victor Felix, J Allen Baron, Rebecca Jackson, Susan M. Bello, Cynthia Bearer, Richard Lichenstein, Katharine Bisordi, Nicole Campion Dialo, Michelle Giglio, and Carol Greene
A standardized nomenclature for mammalian histone genes., Ruth L Seal, Paul Denny, Elspeth A Bruford, Anna K Gribkova, David Landsman, William F Marzluff, Monica McAndrews, Anna R Panchenko, Alexey K Shaytan, and Paul B Talbert
Multi-scale phase separation by explosive percolation with single-chromatin loop resolution., Kaustav Sengupta, Michał Denkiewicz, Mateusz Chiliński, Teresa Szczepińska, Ayatullah Faruk Mollah, Sevastianos Korsak, Raissa D'Souza, Yijun Ruan, and Dariusz Plewczynski
Regulated dicing of pre-mir-144 via reshaping of its terminal loop., Renfu Shang, Dmitry A Kretov, Scott I Adamson, Thomas Treiber, Nora Treiber, Jeffrey Vedanayagam, Jeffrey H Chuang, Gunter Meister, Daniel Cifuentes, and Eric C Lai
A Need for More Molecular Profiling in Brain Metastases., Erica Shen, Amanda E D Van Swearingen, Meghan J Price, Ketan Bulsara, Roel G W Verhaak, César Baëta, Brice D Painter, Zachary J Reitman, April K S Salama, Jeffrey M Clarke, Carey K Anders, Peter E Fecci, C Rory Goodwin, and Kyle M Walsh
Stride-level analysis of mouse open field behavior using deep-learning-based pose estimation., Keith Sheppard, Justin Gardin, Gautam S Sabnis, Asaf Peer, Megan Darrell, Sean P Deats, Brian Q Geuther, Cathleen Lutz, and Vivek Kumar
Transcriptional and Translational Dynamics of Zika and Dengue Virus Infection., Kamini Singh, Maria Guadalupe Martinez, Jianan Lin, James Gregory, Trang Uyen Nguyen, Rawan Abdelaal, Kristy Kang, Kristen Brennand, Arnold Grünweller, Zhengqing Ouyang, Hemali Phatnani, Margaret Kielian, and Hans-Guido Wendel
Common Genetic Variants Contribute to Risk of Transposition of the Great Arteries., Doris Škorić-Milosavljević, Rafik Tadros, Fernanda M Bosada, Federico Tessadori, Jan Hendrik van Weerd, Odilia I Woudstra, Fleur V Y Tjong, Najim Lahrouchi, Fanny Bajolle, Heather J Cordell, A J Agopian, Gillian M Blue, Daniela Q C M Barge-Schaapveld, Marc Gewillig, Christoph Preuss, Elisabeth M Lodder, Phil Barnett, Aho Ilgun, Leander Beekman, Karel van Duijvenboden, Regina Bokenkamp, Martina Müller-Nurasyid, Hubert W Vliegen, Thelma C Konings, Joost P van Melle, Arie P J van Dijk, Roland R J van Kimmenade, Jolien W Roos-Hesselink, Gertjan T Sieswerda, Folkert Meijboom, Hashim Abdul-Khaliq, Felix Berger, Sven Dittrich, Marc-Phillip Hitz, Julia Moosmann, Frank-Thomas Riede, Stephan Schubert, Pilar Galan, Mark Lathrop, Hans M Munter, Ammar Al-Chalabi, Christopher E Shaw, Pamela J Shaw, Karen E Morrison, Jan H Veldink, Leonard H van den Berg, Sylvia Evans, Marcelo A Nobrega, Ivy Aneas, Milena Radivojkov-Blagojević, Thomas Meitinger, Erwin Oechslin, Tapas Mondal, Lynn Bergin, John F Smythe, Luis Altamirano-Diaz, Jane Lougheed, Berto J Bouma, Marie-A Chaix, Jennie Kline, Anne S Bassett, Gregor Andelfinger, Roel L F van der Palen, Patrice Bouvagnet, Sally-Ann B Clur, Jeroen Breckpot, Wilhelmina S Kerstjens-Frederikse, David S Winlaw, Ulrike M M Bauer, Seema Mital, Elizabeth Goldmuntz, Bernard Keavney, Damien Bonnet, Barbara J Mulder, Michael W T Tanck, Jeroen Bakkers, Vincent M Christoffels, Cornelis J Boogerd, Alex V Postma, and Connie R Bezzina
A-Kinase Anchor Protein 1 deficiency causes mitochondrial dysfunction in mouse model of hyperoxia induced acute lung injury., Ramani Soundararajan, Helena Hernández-Cuervo, Timothy M Stearns, Anthony J Griswold, Sahebgowda Sidramagowda Patil, Jutaro Fukumoto, Venkata Ramireddy Narala, Lakshmi Galam, Richard Lockey, and Narasaiah Kolliputi
Large-Scale CRISPRi and Transcriptomics of Staphylococcus epidermidis Identify Genetic Factors Implicated in Lifestyle Versatility., Michelle Spoto, Johanna P. Riera Puma, Elizabeth Fleming, Changhui Guan, Yvette Ondouah Nzutchi, Dean Kim, and Julia Oh
Deep phenotyping: symptom annotation made simple with SAMS., Robin Steinhaus, Sebastian Proft, Evelyn Seelow, Tobias Schalau, Peter N Robinson, and Dominik Seelow
FABIAN-variant: predicting the effects of DNA variants on transcription factor binding., Robin Steinhaus, Peter N Robinson, and Dominik Seelow
Analysis of Salmonella Typhi Pathogenesis in a Humanized Mouse Model., Taylor A Stepien, Stephen J Libby, Joyce E Karlinsey, Michael A Brehm, Dale L Greiner, Leonard D. Shultz, Thea Brabb, and Ferric C Fang
Lifespan benefits for the combination of rapamycin plus acarbose and for captopril in genetically heterogeneous mice., Randy Strong, Richard A Miller, Catherine J Cheng, James F Nelson, Jonathan Gelfond, Shailaja Kesaraju Allani, Vivian Diaz, Angela Olsen Dorigatti, Jonathan Dorigatti, Elizabeth Fernandez, Andrzej Galecki, Brett Ginsburg, Karyn L Hamilton, Martin A Javors, Kerry Kornfeld, Matt Kaeberlein, Suja Kumar, David B Lombard, Marisa Lopez-Cruzan, Benjamin F Miller, Peter Rabinovitch, Peter C. Reifsnyder, Nadia Rosenthal, Molly A. Bogue, Adam B Salmon, Yousin Suh, Eric Verdin, Herbert Weissbach, John Newman, Francesca Maccchiarini, and David E. Harrison
Witch Nails (Krt90whnl): A spontaneous mouse mutation affecting nail growth and development., John P Sundberg, Hannah Galantino-Homer, Heather Fairfield, Patricia F. Ward-Bailey, Belinda S. Harris, Melissa L. Berry, C Herbert Pratt, Nicholas E Gott, Lesley S Bechtold, Pauline R Kaplan, Blythe P Durbin-Johnson, David M Rocke, and Robert H Rice
Animals, quality and the pursuit of relevance., Karen L. Svenson, Stephen D Krasinski, Michael Ellis, Nadia Rosenthal, Edison Liu, and Kenneth H Fasman
Transcriptional control of retinal ganglion cell death after axonal injury., Stephanie B Syc-Mazurek, Hongtian Stanley Yang, Olivia J Marola, Gareth R Howell, and Richard T Libby
TALE.Sense: A Versatile DNA Sensor Platform for Live Mammalian Cells., Aziz Taghbalout, Nathaniel L. Jillette, and Albert W Cheng
3D patient-derived tumor models to recapitulate pediatric brain tumors In Vitro., Min D Tang-Schomer, Harshpreet Chandok, Wei-Biao Wu, Ching C Lau, Markus J Bookland, and Joshy George
Single-cell analysis of endometriosis reveals a coordinated transcriptional programme driving immunotolerance and angiogenesis across eutopic and ectopic tissues., Yuliana Tan, William F Flynn, Santhosh Sivajothi, Diane Luo, Suleyman B Bozal, Monica Davé, Anthony A Luciano, Paul Robson, Danielle E Luciano, and Elise T Courtois
Integrated DNA Copy Number and Expression Profiling Identifies IGF1R as a Prognostic Biomarker in Pediatric Osteosarcoma., Aaron M Taylor, Jiayi M Sun, Alexander Yu, Horatiu Voicu, Jianhe Shen, Donald A Barkauskas, Timothy J Triche, Julie M Gastier-Foster, Tsz-Kwong Man, and Ching C Lau
Genetic resiliency associated with dominant lethal TPM1 mutation causing atrial septal defect with high heritability, Polakit Teekakirikul, Wenjuan Zhu, Xinxiu Xu, Cullen B Young, Tuantuan Tan, Amanda M Smith, Chengdong Wang, Kevin A Peterson, George C Gabriel, Sebastian Ho, Yi Sheng, Anne Moreau de Bellaing, Daniel A Sonnenberg, Jiuann-Huey Lin, Elisavet Fotiou, Gennadiy Tenin, Michael X Wang, Yijen L Wu, Timothy Feinstein, William Devine, Honglan Gou, Abha S Bais, Benjamin J Glennon, Maliha Zahid, Timothy C Wong, Ferhaan Ahmad, Michael J Rynkiewicz, William J Lehman, Bernard Keavney, Tero-Pekka Alastalo, Mary-Louise Freckmann, Kyle Orwig, Stephen A Murray, Stephanie M Ware, Hui Zhao, Brian Feingold, and Cecilia W Lo
GZMK(high) CD8(+) T effector memory cells are associated with CD15(high) neutrophil abundance in non-metastatic colorectal tumors and predict poor clinical outcome, Silvia Tiberti, Carlotta Catozzi, Ottavio Croci, Mattia Ballerini, Danilo Cagnina, Chiara Soriani, Caterina Scirgolea, Zheng Gong, Jiatai He, Angeli D Macandog, Amir Nabinejad, Carina B Nava Lauson, Arianna Quinte', Giovanni Bertalot, Wanda L Petz, Simona P Ravenda, Valerio Licursi, Paola Paci, Marco Rasponi, Luca Rotta, Nicola Fazio, Guangwen Ren, Uberto Fumagalli-Romario, Martin H Schaefer, Stefano Campaner, Enrico Lugli, Luigi Nezi, and Teresa Manzo
Germline thymidylate synthase deficiency impacts nucleotide metabolism and causes dyskeratosis congenita., Hemanth Tummala, Amanda Walne, Roberto Buccafusca, Jenna Alnajar, Anita Szabo, Peter N Robinson, Allyn McConkie-Rosell, Meredith Wilson, Suzanne Crowley, Veronica Kinsler, Anna-Maria Ewins, Pradeepa M Madapura, Manthan Patel, Nikolas Pontikos, Veryan Codd, Tom Vulliamy, and Inderjeet Dokal
c-MYC-USP49-BAG2 axis promotes proliferation and chemoresistance of colorectal cancer cells in vitro., Rongfu Tu, Wenqian Kang, Ye Kang, Ziyi Chen, Peng Zhang, Xiaofan Xiong, Junpeng Ma, Run-Lei Du, and Chengsheng Zhang
The emerging role of deubiquitylating enzymes as therapeutic targets in cancer metabolism., Rongfu Tu, Junpeng Ma, Peng Zhang, Ye Kang, Xiaofan Xiong, Junsheng Zhu, Miao Li, and Chengsheng Zhang
Single-cell multi-omics reveals dyssynchrony of the innate and adaptive immune system in progressive COVID-19., Avraham Unterman, Tomokazu S Sumida, Nima Nouri, Xiting Yan, Amy Y Zhao, Victor Gasque, Jonas C Schupp, Hiromitsu Asashima, Yunqing Liu, Carlos Cosme, Wenxuan Deng, Ming Chen, Micha Sam Brickman Raredon, Kenneth B Hoehn, Guilin Wang, Zuoheng Wang, Giuseppe DeIuliis, Neal G Ravindra, Ningshan Li, Christopher Castaldi, Patrick Wong, John Fournier, Santos Bermejo, Lokesh Sharma, Arnau Casanovas-Massana, Chantal B F Vogels, Anne L Wyllie, Nathan D Grubaugh, Anthony Melillo, Hailong Meng, Yan Stein, Maksym Minasyan, Subhasis Mohanty, William E Ruff, Inessa Cohen, Khadir Raddassi, Laura E Niklason, Albert I Ko, Ruth R Montgomery, Shelli F Farhadian, Akiko Iwasaki, Albert C Shaw, David van Dijk, Hongyu Zhao, Steven H Kleinstein, David A Hafler, Naftali Kaminski, and Charles S Dela Cruz
CCR5: The Receptor That Unlocks the Door for HIV Entry into Cells., Derya Unutmaz
MYC regulates a pan-cancer network of co-expressed oncogenic splicing factors., Laura M Urbanski, Mattia Brugiolo, SungHee Park, Brittany Lynn Angarola, Nathan Leclair, Marina Yurieva, Phil Palmer, Sangram Keshari Sahu, and Olga Anczuków
Glioma progression is shaped by genetic evolution and microenvironment interactions., Frederick S Varn, Kevin C Johnson, Jan Martinek, Jason T Huse, MacLean P Nasrallah, Pieter Wesseling, Lee A D Cooper, Tathiane M Malta, Taylor E Wade, Thais S Sabedot, Daniel Brat, Peter V Gould, Adelheid Wöehrer, Kenneth Aldape, Azzam Ismail, Santhosh Sivajothi, Floris P Barthel, Hoon Kim, Emre Kocakavuk, Nazia Ahmed, Kieron White, Indrani Datta, Hyo-Eun Moon, Steven Pollock, Christine Goldfarb, Ga-Hyun Lee, Luciano Garofano, Kevin J Anderson, Djamel Nehar-Belaid, Jill S Barnholtz-Sloan, Spyridon Bakas, Annette T Byrne, Fulvio D'Angelo, Hui K Gan, Mustafa Khasraw, Simona Migliozzi, D Ryan Ormond, Sun Ha Paek, Erwin G Van Meir, Annemiek M E Walenkamp, Colin Watts, Tobias Weiss, Michael Weller, Karolina Palucka, Lucy F Stead, Laila M Poisson, Houtan Noushmehr, Antonio Iavarone, and Roel G W Verhaak
A comprehensive long-read isoform analysis platform and sequencing resource for breast cancer., Diogo Troggian Veiga, Alex V Nesta, Yuqi Zhao, Anne Deslattes Mays, Richie Huynh, Robert J Rossi, Te-Chia Wu, Karolina Palucka, Olga Anczuków, Christine R Beck, and Jacques Banchereau
Targeting p21Cip1 highly expressing cells in adipose tissue alleviates insulin resistance in obesity, Lichao Wang, Binsheng Wang, Nathan S Gasek, Yueying Zhou, Rachel L Cohn, Dominique E Martin, Wulin Zuo, William F Flynn, Chun Guo, Evan R Jellison, Taewan Kim, Larissa G P Langhi Prata, Allyson K Palmer, Ming Li, Christina L Inman, Lauren S Barber, Iman M A Al-Naggar, Yanjiao Zhou, Wenqiang Du, Kshitiz, George A Kuchel, Alexander Meves, Tamar Tchkonia, James L Kirkland, Paul Robson, and Ming Xu
Brain and spinal cord lesions in 28 inbred strains of aging mice., Jerrold M Ward, Peter Vogel, and John P Sundberg
Identification of Arhgef12 and Prkci as genetic modifiers of retinal dysplasia in the Crb1rd8 mouse model., Sonia M Weatherly, Gayle B. Collin, Jeremy R. Charette, Lisa Stone, Nattaya Damkham, Lillian F Hyde, James G Peterson, Wanda L. Hicks, Gregory W. Carter, Juergen K. Naggert, Mark P. Krebs, and Patsy M. Nishina
Independent and Interactive Effects of Genetic Background and Sex on Tissue Metabolomes of Adipose, Skeletal Muscle, and Liver in Mice., Ann E Wells, William T Barrington, Stephen Dearth, Nikhil Milind, Gregory W. Carter, David W Threadgill, Shawn R Campagna, and Brynn H Voy
Improving racial diversity in the genomics workforce: An examination of challenges and opportunities., Catherine Wicklund, Kunal Sanghavi, Bernice Coleman, Katherine Johansen Taber, Jacquelyn Y Taylor, Kathryn C Asalone, and Sarah Beachy
A research agenda to support the development and implementation of genomics-based clinical informatics tools and resources., Ken Wiley, Laura Findley, Madison Goldrich, Tejinder K Rakhra-Burris, Ana Stevens, Pamela Williams, Carol J Bult, Rex Chisholm, Patricia Deverka, Geoffrey S Ginsburg, Eric D Green, Gail Jarvik, George A Mensah, Erin Ramos, Mary V Relling, Dan M Roden, Robb Rowley, Gil Alterovitz, Samuel Aronson, Lisa Bastarache, James J Cimino, Erin L Crowgey, Guilherme Del Fiol, Robert R Freimuth, Mark A Hoffman, Janina Jeff, Kevin Johnson, Kensaku Kawamoto, Subha Madhavan, Eneida A Mendonca, Lucila Ohno-Machado, Siddharth Pratap, Casey Overby Taylor, Marylyn D Ritchie, Nephi Walton, Chunhua Weng, Teresa Zayas-Cabán, Teri A Manolio, and Marc S Williams
Sequencing and assembling bear genomes: the bare necessities., Courtney Willey and Ron Korstanje
Considerations for policymakers for improving health care through telegenetics: A points to consider statement of the American College of Medical Genetics and Genomics (ACMG)., Heather E Williams, Lila Aiyar, Mary Beth Dinulos, David Flannery, Michelle L McClure, Michele A Lloyd-Puryear, Kunal Sanghavi, Tracy L Trotter, David Viskochil, and ACMG Advocacy and Government Affairs Committee
Functional elements of the cis-regulatory lincRNA-p21., Lauren Winkler, Maria Jimenez, Joshua T Zimmer, Adam Williams, Matthew D Simon, and Nadya Dimitrova
A Genomically and Clinically Annotated Patient-Derived Xenograft Resource for Preclinical Research in Non-Small Cell Lung Cancer., Xing Yi Woo, Anuj Srivastava, Philip C Mack, Joel H. Graber, Brian J Sanderson, Michael W Lloyd, Mandy Chen, Sergii Domanskyi, Regina Gandour-Edwards, Rebekah A Tsai, James G. Keck, Mingshan Cheng, Margaret Bundy, Emily L Jocoy, Jonathan W Riess, William Holland, Stephen C. Grubb, James G Peterson, Grace Stafford, Carolyn Paisie, Steven Neuhauser, Radha Krishna Murthy Karuturi, Joshy George, Allen K. Simons, Margaret Chavaree, Clifford G Tepper, Neal Goodwin, Susan Airhart, Primo N Lara, Thomas H Openshaw, Edison Liu, David R Gandara, and Carol J Bult
Identifying genetic determinants of inflammatory pain in mice using a large-scale gene-targeted screen., Janine M Wotton, Emma Peterson, Ann M Flenniken, Rasneer S Bains, Surabi Veeraragavan, Lynette R Bower, Jason A. Bubier, Marc Parisien, Alexandr Bezginov, Hamed Haselimashhadi, Jeremy Mason, Michayla A Moore, Michelle E Stewart, Dave A Clary, Daniel J Delbarre, Laura C. Anderson, Abigail D'Souza, Leslie Goodwin, Mark E Harrison, Ziyue Huang, Matthew Mckay, Dawei Qu, Luis Santos, Subhiksha Srinivasan, Rachel Urban, Igor Vukobradovic, Christopher S Ward, Amelia M Willett, Robert E Braun, Steve D M Brown, Mary E Dickinson, Jason D Heaney, Vivek Kumar, K C Kent Lloyd, Ann-Marie Mallon, Colin McKerlie, Stephen A. Murray, Lauryl M J Nutter, Helen Parkinson, John R Seavitt, Sara Wells, Rodney C Samaco, Elissa J Chesler, Damian Smedley, Luda Diatchenko, Kyle M Baumbauer, Erin E Young, Robert P Bonin, Silvia Mandillo, and Jacqueline K White
Age and diet shape the genetic architecture of body weight in diversity outbred mice., Kevin M Wright, Andrew Deighan, Andrea Di Francesco, Adam Freund, Vladimir Jojic, Gary Churchill, and Anil Raj
Natural Coevolution of Tumor and Immunoenvironment in Glioblastoma., Lingxiang Wu, Wei Wu, Junxia Zhang, Zheng Zhao, Liangyu Li, Mengyan Zhu, Min Wu, Fan Wu, Fengqi Zhou, Yuxin Du, Rui-Chao Chai, Wei Zhang, Xiaoguang Qiu, Quanzhong Liu, Ziyu Wang, Jie Li, Kening Li, Apeng Chen, Yinan Jiang, Xiangwei Xiao, Han Zou, Rashmi Srivastava, Tingting Zhang, Yun Cai, Yuan Liang, Bin Huang, Ruohan Zhang, Fan Lin, Lang Hu, Xiuxing Wang, Xu Qian, Sali Lv, Baoli Hu, Siyuan Zheng, Zhibin Hu, Hongbing Shen, Yongping You, Roel G W Verhaak, Tao Jiang, and Qianghu Wang
Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia., Dan Xia, Steve Lianoglou, Thomas Sandmann, Meredith Calvert, Jung H Suh, Elliot Thomsen, Jason Dugas, Michelle E Pizzo, Sarah L DeVos, Timothy K Earr, Chia-Ching Lin, Sonnet Davis, Connie Ha, Amy Wing-Sze Leung, Hoang Nguyen, Roni Chau, Ernie Yulyaningsih, Isabel Lopez, Hilda Solanoy, Shababa T Masoud, Chun-Chi Liang, Karin Lin, Giuseppe Astarita, Nathalie Khoury, Joy Yu Zuchero, Robert G Thorne, Kevin Shen, Stephanie Miller, Jorge J Palop, Dylan Garceau, Michael Sasner, Jennifer D Whitesell, Julie A Harris, Selina Hummel, Johannes Gnörich, Karin Wind, Lea Kunze, Artem Zatcepin, Matthias Brendel, Michael Willem, Christian Haass, Daniel Barnett, Till S Zimmer, Anna G Orr, Kimberly Scearce-Levie, Joseph W Lewcock, Gilbert Di Paolo, and Pascal E Sanchez
Architecture of the outbred brown fat proteome defines regulators of metabolic physiology., Haopeng Xiao, Luiz H M Bozi, Yizhi Sun, Christopher L Riley, Vivek M. Philip, Mandy Chen, Jiaming Li, Tian Zhang, Evanna L Mills, Margo P Emont, Wenfei Sun, Anita Reddy, Ryan Garrity, Jiani Long, Tobias Becher, Laura Potano Vitas, Dina Laznik-Bogoslavski, Martha Ordonez, Xinyue Liu, Xiong Chen, Yun Wang, Weihai Liu, Nhien Tran, Yitong Liu, Yang Zhang, Aaron M Cypess, Andrew P White, Yuchen He, Rebecca Deng, Heiko Schöder, Joao A Paulo, Mark P Jedrychowski, Alexander S Banks, Yu-Hua Tseng, Paul Cohen, Linus T Tsai, Evan D Rosen, Samuel Klein, Maria Chondronikola, Fiona E McAllister, Nick Van Bruggen, Edward L Huttlin, Bruce M Spiegelman, Gary Churchill, Steven P Gygi, and Edward T Chouchani
Deletion of Gdf15 Reduces ER Stress-induced Beta-cell Apoptosis and Diabetes., Guanlan Xu, Junqin Chen, SeongHo Jo, Truman B Grayson, Sasanka Ramanadham, Akio Koizumi, Emily L Germain-Lee, Se-Jin Lee, and Anath Shalev
Spatiotemporal dynamics of clonal selection and diversification in normal endometrial epithelium., Manako Yamaguchi, Hirofumi Nakaoka, Kazuaki Suda, Kosuke Yoshihara, Tatsuya Ishiguro, Nozomi Yachida, Kyota Saito, Haruka Ueda, Kentaro Sugino, Yutaro Mori, Kaoru Yamawaki, Ryo Tamura, Sundaramoorthy Revathidevi, Teiichi Motoyama, Kazuki Tainaka, Roel G W Verhaak, Ituro Inoue, and Takayuki Enomoto
PhenoRerank: A re-ranking model for phenotypic concept recognition pre-trained on human phenotype ontology., Shankai Yan, Ling Luo, Po-Ting Lai, Daniel Veltri, Andrew J Oler, Sandhya Xirasagar, Rajarshi Ghosh, Morgan Similuk, Peter N Robinson, and Zhiyong Lu
Studying extrachromosomal DNA with the ecTag method., Eunhee Yi
Extrachromosomal DNA amplifications in cancer., Eunhee Yi, Rocío Chamorro González, Anton G Henssen, and Roel G W Verhaak
Live-Cell Imaging Shows Uneven Segregation of Extrachromosomal DNA Elements and Transcriptionally Active Extrachromosomal DNA Hubs in Cancer., Eunhee Yi, Amit D Gujar, Molly Guthrie, Hoon Kim, Dacheng Zhao, Kevin C Johnson, Samirkumar B Amin, Megan L Costa, Qianru Yu, Sunit Das, Nathaniel L. Jillette, Patricia A Clow, Albert W Cheng, and Roel G W Verhaak
Genetic quality: a complex issue for experimental study reproducibility., Atsushi Yoshiki, Gregory Ballard, and Ana V Perez
Distinct miRNAs associated with various clinical presentations of SARS-CoV-2 infection., Qiqi Zeng, Xin Qi, Junpeng Ma, Fang Hu, Xiaorui Wang, Hongyu Qin, Mengyang Li, Shaoxin Huang, Yong Yang, Yixin Li, Han Bai, Meng Jiang, Doudou Ren, Ye Kang, Yang Zhao, Xiaobei Chen, Xi Ding, Di Ye, Yankui Wang, Jianguo Jiang, Dong Li, Xi Chen, Ke Hu, Binghong Zhang, Bingyin Shi, and Chengsheng Zhang
Intermittent fasting and caloric restriction interact with genetics to shape physiological health in mice., Guozhu Zhang, Andrew Deighan, Anil Raj, Laura Robinson, Hannah J Donato, Gaven Garland, Mackenzie Leland, Baby Martin-McNulty, Ganesh A Kolumam, Johannes Riegler, Adam Freund, Kevin M Wright, and Gary A Churchill
Causes of death and conditional survival estimates of long-term lung cancer survivors., Qun Zhang, Yuan Dai, Hongda Liu, Wenkui Sun, Yuming Huang, Zheng Gong, Shanlin Dai, Hui Kong, and Weiping Xie
Lineage-coupled clonal capture identifies clonal evolution mechanisms and vulnerabilities of BRAF, Ze-Yan Zhang, Yingwen Ding, Ravesanker Ezhilarasan, Tenzin Lhakhang, Qianghu Wang, Jie Yang, Aram S Modrek, Hua Zhang, Aristotelis Tsirigos, Andrew Futreal, Giulio F Draetta, Roel G W Verhaak, and Erik P Sulman
SMN protein is required throughout life to prevent spinal muscular atrophy disease progression., Xin Zhao, Zhihua Feng, Nicole Risher, Anna Mollin, Josephine Sheedy, Karen K Y Ling, Jana Narasimhan, Amal Dakka, John D Baird, Hasane Ratni, Cathleen Lutz, Karen S Chen, Nikolai A Naryshkin, Chien-Ping Ko, Ellen Welch, Friedrich Metzger, and Marla Weetall
Molecular Mechanisms of ARID5B-Mediated Genetic Susceptibility to Acute Lymphoblastic Leukemia., Xujie Zhao, Maoxiang Qian, Charnise Goodings, Yang Zhang, Wenjian Yang, Ping Wang, Beisi Xu, Cheng Tian, Ching-Hon Pui, Stephen P Hunger, Elizabeth A Raetz, Meenakshi Devidas, Mary V Relling, Mignon L Loh, Daniel Savic, Chunliang Li, and Jun J Yang
Epigenetic activation of the FLT3 gene by ZNF384 fusion confers a therapeutic susceptibility in acute lymphoblastic leukemia., Xujie Zhao, Ping Wang, Jonathan D Diedrich, Brandon Smart, Noemi Reyes, Satoshi Yoshimura, Jingliao Zhang, Wentao Yang, Kelly Barnett, Beisi Xu, Zhenhua Li, Xin Huang, Jiyang Yu, Kristine Crews, Allen Eng Juh Yeoh, Marina Konopleva, Chia-Lin Wei, Ching-Hon Pui, Daniel Savic, and Jun J Yang
Exploratory studies of oral and fecal microbiome in healthy human aging., Xin Zhou, Baohong Wang, Patrick C Demkowicz, Jethro Johnson, Yanfei Chen, Daniel Spakowicz, Yanjiao Zhou, Yair Dorsett, Lei Chen, Erica Sodergren, George A Kuchel, and George M. Weinstock
JACKIE: Fast Enumeration of Genome-Wide Single- and Multicopy CRISPR Target Sites and Their Off-Target Numbers., Jacqueline Jufen Zhu and Albert Cheng
Guilt by association: EcDNA as a mobile transactivator in cancer., Yanfen Zhu, Liang Gong, and Chia-Lin Wei