Students participate in an ongoing research program with the support of an experienced scientific mentor. They develop an independent project, implement their plan, analyze the data, and report the results. At the end of the summer, they present their findings to researchers, other students, and parents.
Submissions from 2021
Determining the Role of KZFPs in Modulating Chromatin Accessibilityand Gene Expression in Mouse Embryonic Stem Cells, Alex J. Mora Pagán
Long-Read Sequencing Identifies Structural Variants That Alter Gene Expression In Diverse Mice, Varun Moser
Metabolic regulation of CXCR5 expression in T cells via the kynurenine pathway, Thi-Tina N. Nguyen
Uncovering transcriptional changesrelated to cisplatin treatment andmixing of TNBC subclones usingsingle-cell RNA sequencing, Shadae Nicholas
Characterizing the C57BL/6J-Ighmbp2C495del mouse strainas a model for the study of SMARD1, Harold Peón Castro
Identifying the gut microbe gene products that induce human immune cells to upregulate interferon-gamma production, Veronica Perdomo
Benchmarking algorithms to infer chromatininteractions from single-cell ATAC-seq data, Matthew Signorotti
Testing the Extent a Chemotherapy is Influenced by Host Genetics, Marianna Ward
Multi-species convergent functional genomics analysis of substance usedisorders reveals shared genes in poly-drug use, Bailey E. West
Longitudinal Molecular Characterization of Oligodendrogliomas, Gordon Y. Ye
Submissions from 2019
Characterization of maternal behavior in CS7BL/6J and DBA12J inbred mouse strains, Pura Arroyo Morales
The Effects of Obesity and Genetic Diversity on Adipose TissueAssociated Macrophages, Alan Baez
UNBIASED, K-MER BASED ANALYSIS OF DIFFERENTIALLY PRESENT REPETITIVE ELEMENTS BETWEEN MOUSE SPECIES, Caleigh Charlebois
m6A mRNA modifications containing alternative exons are dynamically regulated in neurological development, Lily Charpentier
Using Deep Learning Neural Networks to Quantify Mouse Gait and Patterns of Social Interaction, Megan Darrell
Modeling the Interaction of Genetic Background and DYRKlA during Neurogenesis among Collaborative Cross Founder ESC-Derived Cerebral Organoids, Alyssa Edwards
The Exacerbation of Vascular Dysfunction with High-Fat Diet in a Novel Mouse Model of Mixed Dementia, Addie Finch
Morphological and Biochemical Effects of a Mntation in an AMD Candidate Gene on RPE Cells, Julia Katherine Mills Alice Fiori
Construction of Computational Pipeline to Analyze Differences in Gene Expression in Inbred Mouse Strains, Maria Flores
Using a Massively-Parallel Reporter Assay to Evaluate Synthetic Enhancer Sequences Acting with Cell Type Specificity, Natalia Fuentes
Network-based prediction of novel genes for congenital diaphragmatic hernia (CDH), Angelina Guerra
Development of R pipeline to predict causal variants underlying expression quantitative trait loci., Stephanie Hoyt
Use of Bioinformatics Tools to Identify Novel Genes Contributing to Lung Cancer Development, Jonathan Judd
Optimization of subcellular protein tracking in hair cells, Anna Kasper
Molecular mechanisms of Kat6b in the differentiation of HSCs, Maximo A. Kesselhaut
RNA-seq Analysis of Sex Differences in the Striatum Cocaine Response of NOD Mice, Violet Kimble
Comparative Analysis of cos+T Cell Function and Immunometabolism in Hybrid Cross Models, Amey Maley
Gene Expression in the Hippocampus of Diversity Outbred Mice Reveals Differences Between Sexes, Meredith Mayer
SAGED-MM: Web Application for the Comprehensive Analysis of Mouse Models, Joshua Mincer
Hippocampal Neuronal Activation during Learning and Memory Processes, Andrea M.C. Mirow
Complexities of Comparative Genomics and the Cardiac Fibrillation Phenotype, Cailey Mitchell
A Universal Drug Based Approach to Treating Dominant Forms of Charcot-Marie-Tooth Disease, Fahad Nabi
Summer Student Report 2019, Blanca Perez
Discovering Signatures of Balancing Selection in Wild Mouse Species, Shaheer Rizwan
A Study of Causal Inference and its Implications in Kinship Correction, Kelsey Robertson
Evaluating Differences in the Growth of Triple-Negative Breast Cancer on Different Genetic Backgrounds, Roberto J. Rodriguez Cartagena
Characterizing genetic control of the 2C state in pluripotent stem cells, Elizabeth Ruark
Epigenetic Inheritance At The Agouti Locus in Mine, Chelsea Schroeder
Modeling transcription factor interaction in biochemically grounded gene regulatory networks, Jainil Shah
Characterization of CFH and the Alternate Complement Pathway in Models for Age Related Macular Degeneration, Hagen (Joki) Wallace
Submissions from 2018
A Computational analysis of cardiac aging using mRNA and protein expression data., Daniel Alfonsetti
Studying the effects of genetic variation on the aminoacyl-tRNA charging pathway using the Diversity Outbred mouse population, Benjamin Allan-Rahill
An Algorithm to Quantitatively Predict Feature-Based Equivalence Between Mouse Inbred Strain Genomes, Rex Asabor
Enhancing Lymph Node Structure in Humanized Mice, Ana Castaner
Transcription factors, their targets, and their role in breast cancer, Jessica Creelman
Understanding the Role of Fibroblasts post-Myocardial Infarction, Maureen Ekwebelem
Inflammasome as an Inflammatory Response to Ocular Hypertension, Annabelle Feist
Characterizing Motor Phenotypes of the Spontaneous Mutant NM5084, Jacqueline Garcia
Development of Parasympathetic Innervation in Aqueous Humor Drainage Structures, Madhumithaq Gautham
Exogenous expression of Scgblcl in understanding its role in cardiac function, Kevin Guerrero
Investigation of the Influence of Nudtl 9 and Dpp 7 Genes on Alzheimer's Disease Progression, Brianna Gurdon
The Effects of AlCF Knock Out on Stressed Mouse Kidneys, Bailey Hixon
Investigating the effects of APOE-£4 on angiogenesis and blood brain barrier integrity in early stages of cerebrovascular development, Larisa Kavetsky
Conservation of Human GWAS Variants in the Mouse Genome, Connor Kean
Rapid Modeling of Developmental Disorders Using CRISPR/ Cas9, Ali Ladha
Pharmacological and Behavioral Characterization of the Reward Pathway in Diverse Mice, Avery Lopez
Stromal regulation of neutrophils during lung metastasis of breast cancer, Sarah Marsden
Identifying the Cause of Decreased Urine pH of Mice on A Caloric Restriction., James Mejia
Identification of Candidate miRNAs as Therapeutic Targets and Biomarkers for Lung Cancer through Differential Expression Analysis, Antonio Mendoza
Framework to Assess Optimal Sequencing Depth Involving Long Noncoding RNAs, Bajram Metjahic
Deciphering Quantitative Phenotypes in Complex Diseases using Gene Co-Expression Modules, Nikhil Milind
Determining the Molecular Mechanisms of Type 1 Diabetes Resistance in Nfkbid Transgenic Non-Obese Diabetic Mice, Anna Quinlan
The Effects of a High-Fat Diet on State-Dependent Activation of the Bed Nucleus of the Stria Terminalis, Katherinne Rabanal
Modeling the Genetic Regulatory Network of Epithelial- Mesenchymal Transition, Dan Ramirez
Developing a Pipeline for Integrating Large Datasets to select candidate Late Onset Alzhei1ner's Disease (LOAD) genes, Sarah Shapley
The Role of STK35 in Germ Cell Development and Fertility, Bailey Shevenell
Identifying genetic interactions related to diabetes using phenotype, Gabriella E. Tenoria
Cell Cycle Profile of Spermatogonial Stem Cells, Diego Trujillo
Lymphocyte Proliferation in response to Cardiomyosin ex vivo, Elias Tzor-Pacheco
Glycine Supplementation in a Mouse Model of Charcot Marie Tooth Type 2D, Kamari Weaver
The Role of TIMP3 Mutation on the Development of Age-Related Macular Degeneration, Nicole Wilkinson
Submissions from 2017
Predicting cancer drug targets using genetic networks., Madelyn Adams
Drivers of pancreatic islet composition., Sadie Allen
Evaluation of concordance of variant to phenotype associations in mouse and human., Cassandra Alvarado
Characterizing sex ratio distortion in the Collaborative Cross., Francesca Barradale
Evaluating machine learning approaches for deciding relevance of ArrayExpress experiments for the Gene Expression Database., Yasmine Boukataya
A reporter system for template bias of meiotic repair in mammals., Emily Bramel
Role of PRDM9 KRAB domain in H3K4 trimethylation at hotspot loci., Naomi Bronkema
Machine learning in the observation of behavioral phenotypes., Gabrielle Cohn
A new GARS mutation, S625L, sensitizes peripheral neurons to degeneration., Donson Cook-Gallardo
Sympathetic innervation of the developing aqueous humor drainage structures., Haelynn Gim
Understanding chemotherapeutic-gene relationships through cross-species analysis., Akeena Harper
Modulation of immune and stromal cells by cancer immunotherapy and chemotherapy in mice., Kevin Hayes
Identification of non-histone protein targets of KMT5A in hematopoietic cells., Teniola Idowu
Genetic drivers of insulin homeostasis., Takanao Ishimura
Mechanistic insights into liposarcoma progression., Ellen Kendall
Identifying addiction related genes through operant sensation seeking in a BXD recombinant inbred panel., Padam Kumar
Understanding the relationship between neuroinflammatory cells and AD-related symptoms through systems genetics., Michelle Kung
Evaluating the therapeutic effect of 2-Deoxy-D-glucose on various cancer models., Nathan Labrie
Characterization of strain specific cardiac macrophage-trophic microenvironments., Kelsey Letson
Examining the role of Dyrkl a in the development and function of inhibitory neurons., Rachel V. Levy
Investigating the role of Rab34 in regulating Hedgehog signaling pathway activity., Amelia Meles
Unbiased profiling of the origin and function of cardiac interstitial cells, Kaesi Morelli
Using gene network analysis to identify novel candidate genes for Congenital Diaphragmatic Hernia (CDH)., Taylar J. Mouton
The genetic mechanism driving risk taking phenotype in BXD recombinant inbred panel., Sartre K. Ndebaneza
Is RNA editing involved in the full recovery of kidneys in Black Bears after hibernation., Selena Neptune-Bear
Research in Action: effectively communicating our translational impact on the JAX.org public website., Grace Niewijk