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    Content Posted in 2013

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    Aberrant sodium channel activity in the complex seizure disorder of Celf4 mutant mice., Wenzhi Sun, Jacy L Wagnon, Connie L. Mahaffey, Michael Briese, Jernej Ule, and Wayne N. Frankel

     

    A context-driven gene prioritization method for web-based functional genomics., Jeremy Jay, E J. Baker, and Elissa J. Chesler

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    Adding metabolomics to the toolbox for studying retinal disease., Gareth R. Howell and Richard T Libby

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    A DNA break- and phosphorylation-dependent positive feedback loop promotes immunoglobulin class-switch recombination., Bao Q Vuong, Kayleigh Herrick-Reynolds, Bharat Vaidyanathan, Joseph N Pucella, Anna J Ucher, Nina M. Donghia, Xiwen Gu, Laura Nicolas, Urszula Nowak, Numa Rahman, Matthew P Strout, Kevin D. Mills, Janet Stavnezer, and Jayanta Chaudhuri

     

    A genetic approach to the prediction of drug side effects: bleomycin induces concordant phenotypes in mice of the collaborative cross., Richard Gelinas, Elissa J. Chesler, Daphne Vasconcelos, Darla R Miller, Yue Yuan, Kai Wang, and David Galas

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    AKAP9 is essential for spermatogenesis and sertoli cell maturation in mice., Kerry J Schimenti, Sky K Feuer, Laurie B Griffin, Nancy R Graham, Claire A Bovet, Suzanne Hartford, Janice Pendola, Carl Lessard, John C Schimenti, and Jeremy O Ward

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    Albuminuria is associated with too few glomeruli and too much testosterone., David A Long, Maria Kolatsi-Joannou, Karen L Price, Cecile Dessapt-Baradez, Jennifer L Huang, Eugenia Papakrivopoulou, Mike Hubank, Ron Korstanje, Luigi Gnudi, and Adrian S Woolf

     

    Algorithm for codevelopment of new drug-predictive biomarker combinations: accounting for inter- and intrapatient tumor heterogeneity., David R Gandara, Tianhong Li, Primo N Lara, Philip C Mack, Karen Kelly, Suzanne Miyamoto, Neal C. Goodwin, Laurel Beckett, and Mary W Redman

     

    Alström Syndrome: Cardiac Magnetic Resonance findings., Francesco Corbetti, Renato Razzolini, Vera Bettini, Jan D. Marshall, Juergen K. Naggert, Francesco Tona, Gabriella Milan, and Pietro Maffei

     

    Alström syndrome is associated with short stature and reduced GH reserve., S Romano, P Maffei, V Bettini, G Milan, F Favaretto, M Gardiman, Jan D. Marshall, N A Greggio, G B Pozzan, G B Collin, Juergen K. Naggert, R Bronson, and R Vettor

     

    Alterations in osteopontin modify muscle size in females in both humans and mice., Eric P Hoffman, Heather Gordish-Dressman, Virginia D McLane, Joseph M Devaney, Paul D Thompson, Paul Visich, Paul M Gordon, Linda S Pescatello, Robert F Zoeller, Niall M Moyna, Theodore J Angelopoulos, Elena Pegoraro, Gregory A. Cox, and Priscilla M Clarkson

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    A mutation in Mtap2 is associated with arrest of mammalian spermatocytes before the first meiotic division., Fengyun Sun and Mary Ann Handel

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    A Mutation in the Nuclear Pore Complex Gene Tmem48 Causes Gametogenesis Defects in Skeletal Fusions with Sterility (sks) Mice., Kouyou Akiyama, Junko Noguchi, Michiko Hirose, Shimpei Kajita, Kentaro Katayama, Maryam Khalaj, Takehito Tsuji, Heather Fairfield, Candice Byers, Laura Reinholdt, Atsuo Ogura, and Tetsuo Kunieda

     

    A new approach for the study of the chemical composition of bordered pit membranes: 4Pi and confocal laser scanning microscopy., Daniela Maschek, Barry Goodell, Jody Jellison, Mark Lessard, and Holger Militz

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    A new in vivo screening paradigm to accelerate antimalarial drug discovery., María Belén Jiménez-Díaz, Sara Viera, Javier Ibáñez, Teresa Mulet, Noemí Magán-Marchal, Helen Garuti, Vanessa Gómez, Lorena Cortés-Gil, Antonio Martínez, Santiago Ferrer, María Teresa Fraile, Félix Calderón, Esther Fernández, Leonard D. Shultz, Didier Leroy, David M Wilson, José Francisco García-Bustos, Francisco Javier Gamo, and Iñigo Angulo-Barturen

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    Ankyrin repeat domain protein 2 and inhibitor of DNA binding 3 cooperatively inhibit myoblast differentiation by physical interaction., Junaith S Mohamed, Michael A Lopez, Gregory A. Cox, and Aladin M Boriek

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    A novel blueprint for 'top down' differentiation defines the cervical squamocolumnar junction during development, reproductive life, and neoplasia., Michael Herfs, Sara O Vargas, Yusuke Yamamoto, Brooke E Howitt, Marisa R Nucci, Jason L Hornick, Frank D. McKeon, Wa Xian, and Christopher P Crum

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    A Novel Mouse Dscam Mutation Inhibits Localization and Shedding of DSCAM., R Dee Schramm, Shuai Li, Belinda S. Harris, Ryan P Rounds, Robert W. Burgess, F Marty Ytreberg, and Peter G Fuerst

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    A pyrrolo-pyrimidine derivative targets human primary AML stem cells in vivo., Yoriko Saito, Hitomi Yuki, Mitsuo Kuratani, Yoshinobu Hashizume, Shinsuke Takagi, Teruki Honma, Akiko Tanaka, Mikako Shirouzu, Junko Mikuni, Noriko Handa, Ikuko Ogahara, Akiko Sone, Yuho Najima, Yuri Tomabechi, Motoaki Wakiyama, Naoyuki Uchida, Mariko Tomizawa-Murasawa, Akiko Kaneko, Satoshi Tanaka, Nahoko Suzuki, Hiroshi Kajita, Yuki Aoki, Osamu Ohara, Leonard D. Shultz, Takehiro Fukami, Toshio Goto, Shuichi Taniguchi, Shigeyuki Yokoyama, and Fumihiko Ishikawa

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    A single cis element maintains repression of the key developmental regulator Gata2., Jonathan W Snow, Jennifer J. Trowbridge, Tohru Fujiwara, Nikla E Emambokus, Jeffrey A Grass, Stuart H Orkin, and Emery H Bresnick

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    ASPP2 suppresses squamous cell carcinoma via RelA/p65-mediated repression of p63., Luca Tordella, Sofia Koch, Victoria Salter, Anna Pagotto, Jessica B Doondeea, Stephan M Feller, Indrika Ratnayaka, Shan Zhong, Robert D Goldin, Guillermina Lozano, Frank D. McKeon, Mahvash Tavassoli, Florian Fritzsche, Gerhard F Huber, Matthias Rössle, Holger Moch, and Xin Lu

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    Attenuating homologous recombination stimulates an AID-induced antileukemic effect., Kristin R. Lamont, Muneer G. Hasham, Nina M. Donghia, Jane Branca, Margaret Chavaree, Betsy Chase, Anne Breggia, Jacquelyn Hedlund, Ivette Emery, Francesca Cavallo, Maria Jasin, Jens Rüter, and Kevin D. Mills

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    A unified anatomy ontology of the vertebrate skeletal system., Wasila M Dahdul, James P Balhoff, David C Blackburn, Alexander D Diehl, Melissa A Haendel, Brian K Hall, Hilmar Lapp, John G Lundberg, Christopher J Mungall, Martin Ringwald, Erik Segerdell, Ceri E Van Slyke, Matthew K Vickaryous, Monte Westerfield, and Paula M Mabee

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    Balancing selection on a regulatory region exhibiting ancient variation that predates human-neandertal divergence., Omer Gokcumen, Qihui Zhu, Lubbertus C F Mulder, Rebecca C Iskow, Christian Austermann, Christopher D Scharer, Towfique Raj, Jeremy M Boss, Shamil Sunyaev, Alkes Price, Barbara Stranger, Viviana Simon, and Charles Lee

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    Basigin null mutant male mice are sterile and exhibit impaired interactions between germ cells and Sertoli cells., Jiajia Bi, Yanfen Li, Fengyun Sun, Anja Saalbach, Claudia Klein, David J Miller, Rex Hess, and Romana A Nowak

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    BCL-XL Mediates the Strong Selective Advantage of a 20q11.21 Amplification Commonly Found in Human Embryonic Stem Cell Cultures., Stuart Avery, Adam J Hirst, Duncan Baker, Chin Yan Lim, Sharmini Alagaratnam, Rolf I Skotheim, Ragnhild A Lothe, Martin F Pera, Alan Colman, Paul Robson, Peter W Andrews, and Barbara B. Knowles

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    Bidirectional communication between oocytes and ovarian follicular somatic cells is required for meiotic arrest of mammalian oocytes., Karen Wigglesworth, Kyung-Bon Lee, Marilyn J. O'Brien, Jia Peng, Martin M Matzuk, and John J. Eppig

     

    Blockade of VEGF receptor-3 aggravates inflammatory bowel disease and lymphatic vessel enlargement., Giorgia Jurisic, John P. Sundberg, and Michael Detmar

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    Bloomsbury report on mouse embryo phenotyping: recommendations from the IMPC workshop on embryonic lethal screening., David Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J Copp, Mary Dickinson, Nicholas D E Greene, Mark Henkelman, Monica Justice, Timothy Mohun, Stephen A Murray, Erwin Pauws, Michael Raess, Janet Rossant, Tom Weaver, and David West

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    Brain involvement in Alström syndrome., Valentina Citton, Angela Favaro, Vera Bettini, Joseph Gabrieli, Gabriella Milan, Nella Augusta Greggio, Jan D. Marshall, Juergen K. Naggert, Renzo Manara, and Pietro Maffei

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    C57BL/6J skin lesion problem eliminated., David D. Myers

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    CAPE: An R Package for Combined Analysis of Pleiotropy and Epistasis., Anna L. Tyler, Wei Lu, Justin J Hendrick, Vivek M. Philip, and Gregory W. Carter

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    Cataracts and microphthalmia caused by a gja8 mutation in extracellular loop 2., Chun-Hong Xia, Bo Chang, Adam M Derosa, Catherine Cheng, Thomas W White, and Xiaohua Gong

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    Cell-type-specific predictive network yields novel insights into mouse embryonic stem cell self-renewal and cell fate., Karen Dowell, Allen K. Simons, Zack Z Wang, Kyuson Yun, and Matthew A. Hibbs

     

    Cervical Squamocolumnar Junction-specific Markers Define Distinct, Clinically Relevant Subsets of Low-grade Squamous Intraepithelial Lesions., Michael Herfs, Carlos Parra-Herran, Brooke E Howitt, Anna R Laury, Marisa R Nucci, Sarah Feldman, Cynthia A Jimenez, Frank D. McKeon, Wa Xian, and Christopher P Crum

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    Changes in ovarian tumor cell number, tumor vasculature, and T cell function monitored in vivo using a novel xenograft model., Sandra J Yokota, John G Facciponte, Raymond J Kelleher, Leonard D. Shultz, Jenni L Loyall, Robert R Parsons, Kunle Odunsi, John G Frelinger, Edith M Lord, Scott A Gerber, Sathy V Balu-Iyer, and Richard B Bankert

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    Cholera toxin subunit B-peptide fusion proteins reveal impaired oral tolerance induction in diabetes-prone but not in diabetes-resistant mice., Maximiliano Presa, Angela Zarama Ortiz, Nahir Garabatos, Cristina Izquierdo, Elisa I Rivas, Luc Teyton, Conchi Mora, David V. Serreze, and Thomas Stratmann

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    Cholesterol metabolism and Rett syndrome pathogenesis., Gabor Nagy and Susan L. Ackerman

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    CHP1-mediated NHE1 biosynthetic maturation is required for Purkinje cell axon homeostasis., Ye Liu, Hans C Zaun, John Orlowski, and Susan L. Ackerman

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    Chromatin stretch enhancer states drive cell-specific gene regulation and harbor human disease risk variants., Stephen C J Parker, Michael L. Stitzel, D Leland Taylor, Jose Miguel Orozco, Michael R Erdos, Jennifer A Akiyama, Kelly Lammerts van Bueren, Peter S Chines, Narisu Narisu, Brian L Black, Axel Visel, Len A Pennacchio, and Francis S Collins

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    Chromosome X loci and spontaneous granulosa cell tumor development in SWR mice: epigenetics and epistasis at work for an ovarian phenotype., Ann M Dorward, Edward S Yaskowiak, Kerri N Smith, Kaitlyn R Stanford, Kathryn L. Shultz, and Wesley G Beamer

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    Clinical utility gene card for: Alström Syndrome - update 2013., Jan D. Marshall, Pietro Maffei, Sebastian Beck, Timothy G Barrett, Richard Paisey, and Juergen K. Naggert

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    CodingMotif: exact determination of overrepresented nucleotide motifs in coding sequences., Yang Ding, William A Lorenz, and Jeffrey Chuang

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    Comparative anatomy of mouse and human nail units., Philip Fleckman, Karin Jaeger, Kathleen Silva, and John P. Sundberg

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    Comparison between two labeled agents in mice using a coinjection-ratio approach in contrast to a conventional group approach., Shuping Dou, Yuzhen Wang, Bruce Barton, Ling Chen, Mary Rusckowski, Leonard D. Shultz, Dale L Greiner, and Guozheng Liu

     

    Comparison of HER2 status by fluorescence in situ hybridization and immunohistochemistry to predict benefit from dose escalation of adjuvant doxorubicin-based therapy in node-positive breast cancer patients., Lynn G Dressler, Donald A Berry, Gloria Broadwater, David Cowan, Kelly Cox, Stephanie Griffin, Ashley Miller, Jessica Tse, Debra Novotny, Diane L Persons, Maurice Barcos, I Craig Henderson, Edison T. Liu, Ann Thor, Dan Budman, Hy Muss, Larry Norton, and Daniel F Hayes

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    Comparison of Two New Mouse Models of Polygenic Type 2 Diabetes at the Jackson Laboratory, NONcNZO10Lt/J and TALLYHO/JngJ., Edward H. Leiter, Marjorie Strobel, Adam O'Neill, David Schultz, Andrew Schile, and Peter C. Reifsnyder

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    Cone Phosphodiesterase-6α' Restores Rod Function and Confers Distinct Physiological Properties in the Rod Phosphodiesterase-6β-Deficient rd10 Mouse., Wen-Tao Deng, Keisuke Sakurai, Saravanan Kolandaivelu, Alexander V Kolesnikov, Astra Dinculescu, Jie Li, Ping Zhu, Xuan Liu, Jijing Pang, Vince A Chiodo, Sanford L Boye, Bo Chang, Visvanathan Ramamurthy, Vladimir J Kefalov, and William W Hauswirth

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    Context-dependent function of "GATA switch" sites in vivo., Jonathan W Snow, Jennifer J. Trowbridge, Kirby D Johnson, Tohru Fujiwara, Nikla E Emambokus, Jeffrey A Grass, Stuart H Orkin, and Emery H Bresnick

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    Cooperative effects of 17β-estradiol and oocyte-derived paracrine factors on the transcriptome of mouse cumulus cells., Chihiro Emori, Karen Wigglesworth, Wataru Fujii, Kunihiko Naito, John J. Eppig, and Koji Sugiura

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    Copy number variation genotyping using family information., Jen-Hwa Chu, Angela Rogers, Iuliana Ionita-Laza, Katayoon Darvishi, Ryan E Mills, Charles Lee, and Benjamin A Raby

     

    Copy number variation prevalence in known asthma genes and their impact on asthma susceptibility., A J Rogers, J-H Chu, K Darvishi, I Ionita-Laza, H Lehmann, R Mills, Charles Lee, and B A Raby

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    Corepressor-dependent silencing of fetal hemoglobin expression by BCL11A., Jian Xu, Daniel E Bauer, Marc A Kerenyi, Thuy D Vo, Serena Hou, Yu-Jung Hsu, Huilan Yao, Jennifer J. Trowbridge, Gail Mandel, and Stuart H Orkin

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    Cross species integration of functional genomics experiments., Jeremy J Jay

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    DEC-205-mediated antigen targeting to steady-state dendritic cells induces deletion of diabetogenic CD8+ T cells independently of PD-1 and PD-L1., Gayatri Mukherjee, Ari Geliebter, Jeffrey Babad, Pere Santamaria, David V. Serreze, Gordon J Freeman, Kristin V Tarbell, Arlene Sharpe, and Teresa P Dilorenzo

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    Decreased APOE-containing HDL subfractions and cholesterol efflux capacity of serum in mice lacking Pcsk9., Seungbum Choi, Aleksandra Aljakna, Ujala Srivastava, Blake R Peterson, Bin Deng, Annik Prat, and Ron Korstanje

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    Deficiency of complement component 5 ameliorates glaucoma in DBA/2J mice., Gareth R. Howell, Ileana Soto, Margaret Ryan, Leah C. Graham, Richard Smith, and Simon W M John

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    Dendritic-cell-based therapeutic cancer vaccines., Karolina Palucka and Jacques Banchereau

     

    Differences in the clinical spectrum of two adolescent male patients with Alström syndrome., Vladimir Kuburović, Jan D. Marshall, Gayle B. Collin, Keith Nykamp, Nina Kuburović, Tatjana Milenković, Sanja Rakić, Milena Djuric, Jovana Ječmenica, Svetislav Milenković, and Juergen K. Naggert

     

    Differential expression of p-ERM, a marker of cell polarity, in benign and neoplastic oviductal epithelium., Gang Ning, Jonathan G Bijron, Ju Yuan, Michelle S Hirsch, Frank D. McKeon, Marisa R Nucci, Christopher P Crum, and Wa Xian

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    Differentiating inbred mouse strains from each other and those with single gene mutations using hair proteomics., Robert H Rice, Katie M Bradshaw, Blythe P Durbin-Johnson, David M Rocke, Richard A Eigenheer, Brett S Phinney, and John P. Sundberg

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    Diverse mechanisms of somatic structural variations in human cancer genomes., Lixing Yang, Lovelace J Luquette, Nils Gehlenborg, Ruibin Xi, Psalm S Haseley, Chih-Heng Hsieh, Chengsheng Zhang, Xiaojia Ren, Alexei Protopopov, Lynda Chin, Raju Kucherlapati, Charles Lee, and Peter J Park

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    DNA binding specificities of the long zinc finger recombination protein PRDM9., Timothy Billings, Emil D Parvanov, Christopher L. Baker, Michael Walker, Kenneth Paigen, and Petko M. Petkov

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    DNA damage induces targeted, genome-wide variation of poly(A) sites in budding yeast., Joel H. Graber, Fathima I Nazeer, Pei-Chun Yeh, Jason N Kuehner, Sneha Borikar, Derick Hoskinson, and Claire L Moore

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    DNA methyltransferase 1 is essential for and uniquely regulates hematopoietic stem and progenitor cells., Jennifer J. Trowbridge, Jonathan W Snow, Jonghwan Kim, and Stuart H Orkin

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    DNase I-hypersensitive exons colocalize with promoters and distal regulatory elements., Tim R Mercer, Stacey L Edwards, Michael B Clark, Shane J Neph, Hao Wang, Andrew B Stergachis, Sam John, Richard Sandstrom, Guoliang Li, Kuljeet S Sandhu, Yijun Ruan, Lars K Nielsen, John S Mattick, and John A Stamatoyannopoulos

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    Dnmt3a silences hematopoietic stem cell self-renewal., Jennifer J. Trowbridge and Stuart H Orkin

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    Dovetailing biology and chemistry: integrating the Gene Ontology with the ChEBI chemical ontology., David P. Hill, Nico Adams, Mike Bada, Colin Batchelor, Tanya Z Berardini, Heiko Dietze, Harold J. Drabkin, Marcus Ennis, Rebecca E Foulger, Midori A Harris, Janna Hastings, Namrata S Kale, Paula de Matos, Christopher J Mungall, Gareth Owen, Paola Roncaglia, Christoph Steinbeck, Steve Turner, and Jane Lomax

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    Dynamic localization of SMC5/6 complex proteins during mammalian meiosis and mitosis suggests functions in distinct chromosome processes., Rocío Gómez, Philip W Jordan, Alberto Viera, Manfred Alsheimer, Tomoyuki Fukuda, Rolf Jessberger, Elena Llano, Alberto M Pendás, Mary Ann Handel, and José A Suja

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    Dynamics of the ethanolamine glycerophospholipid remodeling network., Lu Zhang, Norberto Díaz-Díaz, Kourosh Zarringhalam, Martin Hermansson, Pentti Somerharju, and Jeffrey H. Chuang

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    Effects of low-level organic selenium on lead-induced alterations in neural cell adhesion molecules., Mao Wang, Hongjun Fu, Yongmei Xiao, Baomin Ai, Qing Wei, Shuyu Wang, Tao Liu, Liuqing Ye, and Qiansheng Hu

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    Effects of stimulus salience on touchscreen serial reversal learning in a mouse model of fragile X syndrome., Price E. Dickson, Beau Corkill, Eric McKimm, Mellessa M Miller, Michele A Calton, Daniel Goldowitz, Charles D Blaha, and Guy Mittleman

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    Elevated id2 expression results in precocious neural stem cell depletion and abnormal brain development., Hee Jung Park, Mingi Hong, Roderick T Bronson, Mark A Israel, Wayne N. Frankel, and Kyuson Yun

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    EMAP/EMAPA ontology of mouse developmental anatomy: 2013 update., Terry F. Hayamizu, Michael N Wicks, Duncan R Davidson, Albert Burger, Martin Ringwald, and Richard A Baldock

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    Endogenous retinoids in the pathogenesis of alopecia areata., F Jason Duncan, Kathleen A Silva, Charles J Johnson, Benjamin L King, Jin P Szatkiewicz, Sonya P Kamdar, David E Ong, Joseph L Napoli, Jinshan Wang, Lloyd E King, David A Whiting, Kevin J McElwee, John P. Sundberg, and Helen B Everts

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    Epicutaneous model of community-acquired Staphylococcus aureus skin infections., Ranjani Prabhakara, Oded Foreman, Roberto De Pascalis, Gloria M Lee, Roger D Plaut, Stanley Y Kim, Scott Stibitz, Karen L Elkins, and Tod J Merkel

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    Epidemiological and phylogenetic analysis of institutional mouse parvoviruses., Joongho Joh, Mary L Proctor, Janice L Ditslear, William W King, John P. Sundberg, A Bennett Jenson, and Shin-Je Ghim

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    Essential role of postsynaptic NMDA receptors in developmental refinement of excitatory synapses., Zhong-Wei Zhang, Matthew Peterson, and Hong Liu

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    Expansion of oligodendrocyte progenitor cells following SIRT1 inactivation in the adult brain., Victoria A Rafalski, Peggy P Ho, Jamie O Brett, Duygu Ucar, Jason C Dugas, Elizabeth A Pollina, Lionel M L Chow, Adiljan Ibrahim, Suzanne J Baker, Ben A Barres, Lawrence Steinman, and Anne Brunet

     

    Extreme clinical variability of dilated cardiomyopathy in two siblings with Alström syndrome., Jamal Mahamid, Avraham Lorber, Yoseph Horovitz, Stavit A Shalev, Gayle B. Collin, Juergen K. Naggert, Jan D. Marshall, and Ronen Spiegel

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    Fine map of the Gct1 spontaneous ovarian granulosa cell tumor locus., Kerri N Smith, Sarah J Halfyard, Edward S Yaskowiak, Kathryn L. Shultz, Wesley G. Beamer, and Ann M Dorward

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    Fine time course expression analysis identifies cascades of activation and repression and maps a putative regulator of Mammalian sex determination., Steven C. Munger, Anirudh Natarajan, Loren L Looger, Uwe Ohler, and Blanche Capel

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    FOXO3 Shares Common Targets with ASCL1 Genome-wide and Inhibits ASCL1-Dependent Neurogenesis., Ashley E Webb, Elizabeth A Pollina, Thomas Vierbuchen, Noelia Urbán, Duygu Ucar, Dena S Leeman, Ben Martynoga, Madhavi Sewak, Thomas A Rando, François Guillemot, Marius Wernig, and Anne Brunet

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    Gene Ontology annotation of sequence-specific DNA binding transcription factors: setting the stage for a large-scale curation effort., Sushil Tripathi, Karen R. Christie, Rama Balakrishnan, Rachael Huntley, David P. Hill, Liv Thommesen, Judith A. Blake, Martin Kuiper, and Astrid Lægreid

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    Gene Ontology annotations and resources., Gene Ontology Consortium

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    Generation of islet-like cells from mouse gall bladder by direct ex vivo reprogramming., Raymond D Hickey, Feorillo Galivo, Jonathan Schug, Michael A Brehm, Annelise Haft, Yuhan Wang, Eric Benedetti, Guoqiang Gu, Mark A Magnuson, Leonard D. Shultz, Eric Lagasse, Dale L Greiner, Klaus H Kaestner, and Markus Grompe

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    Gene therapy provides long-term visual function in a pre-clinical model of retinitis pigmentosa., Katherine J Wert, Richard J Davis, Javier Sancho-Pelluz, Patsy M. Nishina, and Stephen H Tsang

     

    Genetic analysis of mesangial matrix expansion in aging mice and identification of far2 as a candidate gene., Gerda A Noordmans, Christina R Caputo, Yuan Huang, Susan M Sheehan, Marian Bulthuis, Peter Heeringa, Jan-Luuk Hillebrands, Harry van Goor, and Ron Korstanje

     

    Genetic and pharmacologic models for type 1 diabetes., Edward H. Leiter and Andrew Schile

     

    Genetic loci that control the loss and regain of trabecular bone during unloading and reambulation., Stefan Judex, Weidong Zhang, Leah Rae Donahue, and Engin Ozcivici

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    Genetic modifier loci of mouse Mfrp(rd6) identified by quantitative trait locus analysis., Jungyeon Won, Jeremy R. Charette, Vivek M. Philip, Timothy M. Stearns, Weidong Zhang, Juergen K. Naggert, Mark P. Krebs, and Patsy M. Nishina

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    Genome-wide association studies of maximum number of drinks., Yue Pan, Xingguang Luo, Xuefeng Liu, Long-Yang Wu, Qunyuan Zhang, Liang Wang, Weize Wang, Lingjun Zuo, and Ke-Sheng Wang

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    Genome-wide mapping of RNA structure using nuclease digestion and high-throughput sequencing., Yue Wan, Kun Qu, Zhengqing Ouyang, and Howard Y Chang

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    Getting ready for the Human Phenome Project: the 2012 forum of the Human Variome Project., William S Oetting, Peter N Robinson, Marc S Greenblatt, Richard G Cotton, Tim Beck, John C Carey, Sandra C Doelken, Marta Girdea, Tudor Groza, Carol M Hamilton, Ada Hamosh, Berit Kerner, Jacqueline A L MacArthur, Donna R Maglott, Barend Mons, Heidi L Rehm, Paul N Schofield, Beverly A Searle, Damian Smedley, Cynthia Smith, Inge Thomsen Bernstein, Andreas Zankl, and Eric Y Zhao

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    GLI1 regulates a novel neuropilin-2/α6β1 integrin based autocrine pathway that contributes to breast cancer initiation., Hira Lal Goel, Bryan Pursell, Cheng Chang, Leslie M Shaw, Junhao Mao, Karl Simin, Prashant Kumar, Craig W Vander Kooi, Leonard D. Shultz, Dale L Greiner, Jens Henrik Norum, Rune Toftgard, Charlotte Kuperwasser, and Arthur M Mercurio

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    G-protein signaling modulator-3, a gene linked to autoimmune diseases, regulates monocyte function and its deficiency protects from inflammatory arthritis., Patrick M Giguère, Matthew J Billard, Geneviève Laroche, Brian K Buckley, Roman G Timoshchenko, Marcus W McGinnis, Denise Esserman, Oded Foreman, Peng Liu, David P Siderovski, and Teresa K Tarrant

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    Grappling with cancer., Edison Liu

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    Growth differentiation factor 9:bone morphogenetic protein 15 heterodimers are potent regulators of ovarian functions., Jia Peng, Qinglei Li, Karen Wigglesworth, Adithya Rangarajan, Chandramohan Kattamuri, Randall T Peterson, John J. Eppig, Thomas B Thompson, and Martin M Matzuk

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    Haploinsufficiency of Dnmt1 impairs leukemia stem cell function through derepression of bivalent chromatin domains., Jennifer J. Trowbridge, Amit U Sinha, Nan Zhu, Mingjie Li, Scott A Armstrong, and Stuart H Orkin

     

    HER-2/neu amplification in benign breast disease and the risk of subsequent breast cancer., A Stark, B S Hulka, S Joens, D Novotny, A D Thor, L E Wold, M J Schell, L J Melton, Edison T. Liu, and K Conway

     

    HER-2/neu and p53 expression versus tamoxifen resistance in estrogen receptor-positive, node-positive breast cancer., D A Berry, H B Muss, A D Thor, L Dressler, Edison T. Liu, G Broadwater, D R Budman, I C Henderson, M Barcos, D Hayes, and L Norton

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    High-precision genetic mapping of behavioral traits in the diversity outbred mouse population., R W Logan, Ray F. Robledo, Jill M. Recla, Vivek M. Philip, Jason A. Bubier, Jeremy Jay, C Harwood, Troy Wilcox, Dan M. Gatti, Carol J. Bult, Gary A. Churchill, and Elissa J. Chesler

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    High-throughput quantification of the mechanical competence of murine femora--a highly automated approach for large-scale genetic studies., D Ruffoni, T Kohler, R Voide, A J Wirth, Leah Rae Donahue, R Müller, and G H van Lenthe

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    Human CD1c+ dendritic cells drive the differentiation of CD103+ CD8+ mucosal effector T cells via the cytokine TGF-β., Chun I Yu, Christian Becker, Yuanyuan Wang, Florentina Marches, Julie Helft, Marylene Leboeuf, Esperanza Anguiano, Stephane Pourpe, Kristina Goller, Virginia Pascual, Jacques Banchereau, Miriam Merad, and Karolina Palucka

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    Human dendritic cells subsets as targets and vectors for therapy., Eynav Klechevsky and Jacques Banchereau

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    Human dendritic cell subsets in vaccination., Karolina Palucka and Jacques Banchereau

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    Human immune system development and survival of non-obese diabetic (NOD)-scid IL2rγ(null) (NSG) mice engrafted with human thymus and autologous haematopoietic stem cells., L Covassin, S Jangalwe, N Jouvet, J Laning, L Burzenski, Leonard D. Shultz, and M A Brehm

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    Humanized mice for the study of infectious diseases., Michael A Brehm, Nathalie Jouvet, Dale L Greiner, and Leonard D. Shultz

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    IBC's 23rd Annual Antibody Engineering, 10th Annual Antibody Therapeutics International Conferences and the 2012 Annual Meeting of The Antibody Society: December 3-6, 2012, San Diego, CA., Peter-Christian Klöhn, Ulrich Wuellner, Nora Zizlsperger, Yu Zhou, Daniel Tavares, Sven Berger, Kirstin A Zettlitz, Gabriele Proetzel, May Yong, Richard H J Begent, and Janice M Reichert

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    IBI* series winner. Students as collaborators in systems biology research., Susan McClatchy, Deborah McGann, Robert Gotwals, Amanda Baskett, and Gary Churchill

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    IL-12 receptor β1 deficiency alters in vivo T follicular helper cell response in humans., Nathalie Schmitt, Jacinta Bustamante, Laure Bourdery, Salah Eddine Bentebibel, Stephanie Boisson-Dupuis, Fran Hamlin, Mau V Tran, Derek Blankenship, Virginia Pascual, Daniel A Savino, Jacques Banchereau, Jean-Laurent Casanova, and Hideki Ueno

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    IL-21 Is a Double-Edged Sword in the Systemic Lupus Erythematosus-like Disease of BXSB.Yaa Mice., Caroline G. McPhee, Jason A. Bubier, Thomas J. Sproule, Giljun Park, Martin P Steinbuck, William H. Schott, Gregory J. Christianson, Herbert C Morse, and Derry C. Roopenian

    Link

    IL-7/anti-IL-7 mAb complexes augment cytokine potency in mice through association with IgG-Fc and by competition with IL-7R., Christopher E Martin, Ester M M van Leeuwen, Se Jin Im, Derry C. Roopenian, Young-Chul Sung, and Charles D Surh

    Link

    Imaging Glioma Initiation In Vivo Through a Polished and Reinforced Thin-skull Cranial Window., Lifeng Zhang, Andree Lapierre, Brittany Roy, Maili Lim, Jennifer Zhu, Wei Wang, Stephen B. Sampson, Kyuson Yun, Bonnie Lyons, Yun Li, and Da-Ting Lin

    Link

    Imaging pHluorin-tagged Receptor Insertion to the Plasma Membrane in Primary Cultured Mouse Neurons., Yun Li, Brittany D Roy, Wei Wang, Lifeng Zhang, Stephen B. Sampson, and Da-Ting Lin

     

    Impact of the Environment on the Skeleton: Is it Modulated by Genetic Factors?, Cheryl L. Ackert-Bicknell and David Karasik

    Link

    Induction of ICOS+CXCR3+CXCR5+ TH cells correlates with antibody responses to influenza vaccination., Salah-Eddine Bentebibel, Santiago Lopez, Gerlinde Obermoser, Nathalie Schmitt, Cynthia Mueller, Carson Harrod, Emilio Flano, Asuncion Mejias, Randy A Albrecht, Derek Blankenship, Hui Xu, Virginia Pascual, Jacques Banchereau, Adolfo Garcia-Sastre, Anna Karolina Palucka, Octavio Ramilo, and Hideki Ueno

    Link

    Inferring gene function and network organization in Drosophila signaling by combined analysis of pleiotropy and epistasis., Gregory W. Carter

     

    Influence of activation state of ErbB-2 (HER-2) on response to adjuvant cyclophosphamide, doxorubicin, and fluorouracil for stage II, node-positive breast cancer: study 8541 from the Cancer and Leukemia Group B., Michael P DiGiovanna, David F Stern, Susan Edgerton, Gloria Broadwater, Lynn G Dressler, Daniel R Budman, I Craig Henderson, Larry Norton, Edison Liu, Hyman B Muss, Donald A Berry, Daniel F Hayes, and Ann D Thor

    Link

    Integration of mouse and human genome-wide association data identifies KCNIP4 as an asthma gene., Blanca E Himes, Keith Sheppard, Annerose Berndt, Adriana S Leme, Rachel A Myers, Christopher R Gignoux, Albert M Levin, W James Gauderman, James J Yang, Rasika A Mathias, Isabelle Romieu, Dara G Torgerson, Lindsey A Roth, Scott Huntsman, Celeste Eng, Barbara Klanderman, John Ziniti, Jody Senter-Sylvia, Stanley J Szefler, Robert F Lemanske, Robert S Zeiger, Robert C Strunk, Fernando D Martinez, Homer Boushey, Vernon M Chinchilli, Elliot Israel, David Mauger, Gerard H Koppelman, Dirkje S Postma, Maartje A E Nieuwenhuis, Judith M Vonk, John J Lima, Charles G Irvin, Stephen P Peters, Michiaki Kubo, Mayumi Tamari, Yusuke Nakamura, Augusto A Litonjua, Kelan G Tantisira, Benjamin A Raby, Eugene R Bleecker, Deborah A Meyers, Stephanie J London, Kathleen C Barnes, Frank D Gilliland, L Keoki Williams, Esteban G Burchard, Dan L Nicolae, Carole Ober, Dawn L DeMeo, Edwin K Silverman, Beverly J Paigen, Gary Churchill, Steve D Shapiro, and Scott T Weiss

    Link

    Integrative genomics of gene and metabolic regulation by estrogen receptors α and β, and their coregulators., Zeynep Madak-Erdogan, Tze-Howe Charn, Yan Jiang, Edison Liu, John A Katzenellenbogen, and Benita S Katzenellenbogen

    Link

    Interaction between Notch signalling and Lunatic fringe during somite boundary formation in the mouse., I B Barrantes, A J Elia, K Wünsch, M H Hrabe de Angelis, T W Mak, J Rossant, R A Conlon, A Gossler, and J L de la Pompa

    Link

    Interleukin-6 is essential for primary resistance to Francisella tularensis live vaccine strain infection., Sherry L Kurtz, Oded Foreman, Catharine M Bosio, Miriam R Anver, and Karen L Elkins

    Link

    InterMOD: integrated data and tools for the unification of model organism research., Julie Sullivan, Kalpana Karra, Sierra A T Moxon, Andrew Vallejos, Howie Motenko, J D Wong, Jelena Aleksic, Rama Balakrishnan, Gail Binkley, Todd Harris, Benjamin Hitz, Pushkala Jayaraman, Rachel Lyne, Steven Neuhauser, Christian Pich, Richard N Smith, Quang Trinh, J Michael Cherry, Joel E Richardson, Lincoln Stein, Simon Twigger, Monte Westerfield, Elizabeth Worthey, and Gos Micklem

    Link

    Intrinsic axonal degeneration pathways are critical for glaucomatous damage., Gareth R. Howell, Ileana Soto, Richard T Libby, and Simon W.M. John

    Link

    Introduction to mechanisms of neural circuit formation., Joshua A Weiner, James D Jontes, and Robert W. Burgess

    PDF

    Joan Staats Oral History, Joan Staats

     

    Knockdown of the hypertension-associated gene NOSTRIN alters glomerular barrier function in zebrafish (Danio rerio)., Torsten Kirsch, Jessica Kaufeld, Ron Korstanje, Dirk M Hentschel, Lynne Staggs, Frank Bollig, Michaela Beese, Patricia Schroder, Lisa Boehme, Hermann Haller, and Mario Schiffer

    Link

    Large-scale functional organization of long-range chromatin interaction networks., Kuljeet Singh Sandhu, Guoliang Li, Huay Mei Poh, Yu Ling Kelly Quek, Yee Yen Sia, Su Qin Peh, Fabianus Hendriyan Mulawadi, Joanne Lim, Mile Sikic, Francesca Menghi, Anbupalam Thalamuthu, Wing Kin Sung, Xiaoan Ruan, Melissa Jane Fullwood, Edison T. Liu, Peter Csermely, and Yijun Ruan

    Link

    Loss-of-Function Mutations in TBC1D20 Cause Cataracts and Male Infertility in blind sterile Mice and Warburg Micro Syndrome in Humans., Ryan P Liegel, Mark T Handley, Adam Ronchetti, Stephen Brown, Lars Langemeyer, Andrea Linford, Bo Chang, Deborah J Morris-Rosendahl, Sarah Carpanini, Renata Posmyk, Verity Harthill, Eamonn Sheridan, Ghada M H Abdel-Salam, Paulien A Terhal, Francesca Faravelli, Patrizia Accorsi, Lucio Giordano, Lorenzo Pinelli, Britta Hartmann, Allison D Ebert, Francis A Barr, Irene A Aligianis, and Duska J Sidjanin

    Link

    Loss of function of the mouse Sharpin gene results in Peyer's patch regression., Rosemarie Seymour, Bobbi-Jo Shirley, Harm Hogenesch, Leonard D. Shultz, and John P. Sundberg

    Link

    Loss of the E3 ubiquitin ligase LRSAM1 sensitizes peripheral axons to degeneration in a mouse model of Charcot-Marie-Tooth disease., Laurent P. Bogdanik, James N Sleigh, Cong Tian, Mark E Samuels, Karen Bedard, Kevin L. Seburn, and Robert W. Burgess

    Link

    Lost and found in behavioral informatics., Melissa A Haendel and Elissa J Chesler

    Link

    Low-grade and high-grade serous Mullerian carcinoma: Review and analysis of publicly available gene expression profiles., Taymaa May, Melina Shoni, Christopher P Crum, Wa Xian, Vinod Vathipadiekal, Michael Birrer, Barry Rosen, Alicia Tone, and K Joan Murphy

    Link

    Meeting report of the 26th International Mammalian Genome Conference., Melissa A Musser, Steven C. Munger, and Teresa M Gunn

     

    MEIOB exhibits single-stranded DNA-binding and exonuclease activities and is essential for meiotic recombination., Mengcheng Luo, Fang Yang, N Adrian Leu, Jessica Landaiche, Mary Ann Handel, Ricardo Benavente, Sophie La Salle, and P Jeremy Wang

    Link

    Microenvironmental protection of CML stem and progenitor cells from tyrosine kinase inhibitors through N-cadherin and Wnt-β-catenin signaling., Bin Zhang, Min Li, Tinisha McDonald, Tessa L Holyoake, Randall T Moon, Dario Campana, Leonard D. Shultz, and Ravi Bhatia

    Link

    Missense mutation in mouse GALC mimics human gene defect and offers new insights into Krabbe disease., Gregory B Potter, Marta Santos, Muriel T. Davisson, David H Rowitch, Dan L Marks, Ernesto R Bongarzone, and Magdalena A Petryniak

    Link

    Modeling hepatic osteodystrophy in Abcb4 deficient mice., Katrin Hochrath, Sabrina Ehnert, Cheryl L. Ackert-Bicknell, Yvonne Lau, Andrea Schmid, Marcin Krawczyk, Jan G Hengstler, Jordanne Dunn, Kanishka Hiththetiya, Birgit Rathkolb, Kateryna Micklich, Wolfgang Hans, Helmut Fuchs, Valérie Gailus-Durner, Eckhard Wolf, Martin Hrabě de Angelis, Steven Dooley, Beverly Paigen, Britt Wildemann, Frank Lammert, and Andreas K Nüssler

    Link

    Modeling host genetic regulation of influenza pathogenesis in the collaborative cross., Martin T Ferris, David L Aylor, Daniel Bottomly, Alan C Whitmore, Lauri D Aicher, Timothy A Bell, Birgit Bradel-Tretheway, Janine T Bryan, Ryan J Buus, Lisa E Gralinski, Bart L Haagmans, Leonard McMillan, Darla R Miller, Elizabeth Rosenzweig, William Valdar, Jeremy Wang, Gary Churchill, David W Threadgill, Shannon K McWeeney, Michael G Katze, Fernando Pardo-Manuel de Villena, Ralph S Baric, and Mark T Heise

     

    Molecular oncodiagnostics: where we are and where we need to go., Edison T. Liu

     

    Mouse colony data management., Charles J. Donnelly and Carol J. Bult

     

    Mouse models for studies of retinal degeneration and diseases., Bo Chang

    Link

    Murine adipose tissue-derived stromal cell apoptosis and susceptibility to oxidative stress in vitro are regulated by genetic background., Robert Pazdro and David E. Harrison

    Link

    Mutant Enpp1asj mice as a model for generalized arterial calcification of infancy., Qiaoli Li, Haitao Guo, David W Chou, Annerose Berndt, John P. Sundberg, and Jouni Uitto

    Link

    Myosin 6 is required for iris development and normal function of the outer retina., Ivy S Samuels, Brent A Bell, Gwen Sturgill-Short, Lindsey A Ebke, Mary Rayborn, Lanying Shi, Patsy M. Nishina, and Neal S Peachey

     

    New point mutation in Golga3 causes multiple defects in spermatogenesis., L F Bentson, V A Agbor, L N Agbor, A C Lopez, L E Nfonsam, S S Bornstein, Mary Ann Handel, and C C Linder

    Link

    Notch1 induced brain tumor models the sonic hedgehog subgroup of human medulloblastoma., Sivaraman Natarajan, Yaochen Li, Emily E Miller, David J Shih, Michael D Taylor, Timothy M. Stearns, Roderick T Bronson, Susan L. Ackerman, Jeong Yoon, and Kyuson Yun

    Link

    Notch2 is required in somatic cells for breakdown of ovarian germ-cell nests and formation of primordial follicles., Jingxia Xu and Thomas Gridley

    Link

    Ontology based molecular signatures for immune cell types via gene expression analysis., Terrance F Meehan, Nicole A Vasilevsky, Christopher J Mungall, David S Dougall, Melissa A Haendel, Judith A. Blake, and Alexander D Diehl

    Link

    Oocyte differentiation is genetically dissociable from meiosis in mice., Gregoriy A Dokshin, Andrew E Baltus, John J. Eppig, and David C Page

    Link

    Opportunities for bioinformatics in the classification of behavior and psychiatric disorders., Elissa J. Chesler and Ryan W Logan

     

    Overcoming current limitations in humanized mouse research., Michael A Brehm, Leonard D. Shultz, Jeremy Luban, and Dale L Greiner

     

    Pathology of rodent models of intestinal cancer: progress report and recommendations., Mary Kay Washington, Anne E Powell, Ruth Sullivan, John P. Sundberg, Nicholas Wright, Robert J Coffey, and William F Dove

     

    Patients with acute myeloid leukemia and RAS mutations benefit most from postremission high-dose cytarabine: a Cancer and Leukemia Group B study., Andreas Neubauer, Kati Maharry, Krzysztof Mrózek, Christian Thiede, Guido Marcucci, Peter Paschka, Robert J Mayer, Richard A Larson, Edison Liu, and Clara D Bloomfield

     

    Performing Integrative Functional Genomics Analysis in GeneWeaver.org., Jeremy Jay and Elissa J Chesler

    Link

    Personalized medicine: does the molecular suit fit?, Edison Liu and Patrick G Johnston

    Link

    Phenotypic overlap in the contribution of individual genes to CNV pathogenicity revealed by cross-species computational analysis of single-gene mutations in humans, mice and zebrafish., Sandra C Doelken, Sebastian Köhler, Christopher J Mungall, Georgios V Gkoutos, Barbara J Ruef, Cynthia Smith, Damian Smedley, Sebastian Bauer, Eva Klopocki, Paul N Schofield, Monte Westerfield, Peter N Robinson, and Suzanna E Lewis

     

    Physiological effects of housing density on C57BL/6J mice over a 9-month period., Beverly Paigen, Karen L. Svenson, R Von Smith, M A Marion, T Stearns, Luanne L. Peters, and A L Smith

    Link

    Polo-like kinase is required for synaptonemal complex disassembly and phosphorylation in mouse spermatocytes., Philip W Jordan, Jesse Karppinen, and Mary Ann Handel

    Link

    Primate genome architecture influences structural variation mechanisms and functional consequences., Omer Gokcumen, Verena Tischler, Jelena Tica, Qihui Zhu, Rebecca C Iskow, Eunjung Lee, Markus Hsi-Yang Fritz, Amy Langdon, Adrian M Stütz, Pavlos Pavlidis, Vladimir Benes, Ryan E Mills, Peter J Park, Charles Lee, and Jan O Korbel

    Link

    Proprotein convertases in high-density lipoprotein metabolism., Seungbum Choi and Ron Korstanje

    Link

    R164C mutation in FOXQ1 H3 domain affects formation of the hair medulla., Baojin Wu, C Herbert Pratt, Christopher S. Potter, Kathleen A. Silva, Victoria E. Kennedy, and John P Sundberg

    Link

    Rapamycin doses sufficient to extend lifespan do not compromise muscle mitochondrial content or endurance., Lan Ye, Anne L Widlund, Carrie A Sims, Dudley W Lamming, Yuxia Guan, James G Davis, David M Sabatini, David E. Harrison, Ole Vang, and Joseph A Baur

    Link

    Recalculation of 23 mouse HDL QTL datasets improves accuracy and allows for better candidate gene analysis., Cheryl L Ackert-Bicknell, Beverly J Paigen, and Ron Korstanje

     

    Receptor tyrosine kinases fall into distinct classes based on their inferred signaling networks., Joel P. Wagner, Alejandro Wolf-Yadlin, Mark Sevecka, Jennifer K Grenier, David E Root, Douglas A Lauffenburger, and Gavin MacBeath

    Link

    Regulation of transcription through acetylation of H3K122 on the lateral surface of the histone octamer., Philipp Tropberger, Sebastian Pott, Claudia Keller, Kinga Kamieniarz-Gdula, Matthieu Caron, Florian Richter, Guohong Li, Gerhard Mittler, Edison T. Liu, Marc Bühler, Raphael Margueron, and Robert Schneider

    Link

    Relationship between obesity phenotypes and genetic determinants in a mouse model for juvenile obesity., Gudrun A Brockmann, Nadine Schäfer, Claudia Hesse, Sebastian Heise, Christina Neuschl, Asja Wagener, Gary Churchill, and Renhua Li

    Link

    Reply to Mottershead et al.: GDF9:BMP15 heterodimers are potent regulators of ovarian functions., Jia Peng, Qinglei Li, Karen Wigglesworth, Adithya Rangarajan, Chandramohan Kattamuri, Randall T Peterson, John J. Eppig, Thomas B Thompson, and Martin M Matzuk

    Link

    Restoration of SMN to Emx-1 expressing cortical neurons is not sufficient to provide benefit to a severe mouse model of Spinal Muscular Atrophy., Alexander S Taylor, Jacqueline J Glascock, Ferrill F Rose, Cathleen Lutz, and Christian L Lorson

    Link

    Retinal ganglion cell dendritic atrophy in DBA/2J glaucoma., Pete A. Williams, Gareth R. Howell, Jessica M Barbay, Catherine E. Braine, Gregory L Sousa, Simon W M John, and James E Morgan

    Link

    Retinal ganglion cell dendritic degeneration in a mouse model of Alzheimer's disease., Pete A. Williams, Rebecca A Thirgood, Huw Oliphant, Aura Frizzati, Elinor Littlewood, Marcela Votruba, Mark A Good, Julie Williams, and James E Morgan

    Link

    Retinoid metabolism is altered in human and mouse cicatricial alopecia., Helen B Everts, Kathleen A Silva, Shalise Montgomery, Liye Suo, Monica Menser, Amy S Valet, Lloyd E King, David E Ong, and John P. Sundberg

    Link

    Retrotransposon insertion in the T-cell acute lymphocytic leukemia 1 (tal1) gene is associated with severe renal disease and patchy alopecia in hairpatches (hpt) mice., Vishnu Hosur, Melissa L Cox, Lisa M Burzenski, Lynn Alley, Bonnie L. Lyons, Anoop Kavirayani, Kimberly A Martin, Gregory A. Cox, Kenneth R. Johnson, Rebecca Riding, and Leonard D. Shultz

    Link

    Segmenting the human genome based on states of neutral genetic divergence., Prabhani Kuruppumullage Don, Guruprasad Ananda, Francesca Chiaromonte, and Kateryna D Makova

    Link

    SeqFold: Genome-scale reconstruction of RNA secondary structure integrating high-throughput sequencing data., Zhengqing Ouyang, Michael P Snyder, and Howard Y Chang

    Link

    SHARPIN Regulates Uropod Detachment in Migrating Lymphocytes., Jeroen Pouwels, Nicola De Franceschi, Pia Rantakari, Kaisa Auvinen, Marika Karikoski, Elina Mattila, Christopher Potter, John P. Sundberg, Nancy Hogg, Carl G Gahmberg, Marko Salmi, and Johanna Ivaska

    Link

    Single-cell DNA-methylation analysis reveals epigenetic chimerism in preimplantation embryos., Chanchao Lorthongpanich, Lih Feng Cheow, Sathish Balu, Stephen R Quake, Barbara B. Knowles, William F Burkholder, Davor Solter, and Daniel M Messerschmidt

    Link

    Statistical analysis of the processes controlling choline and ethanolamine glycerophospholipid molecular species composition., Kourosh Zarringhalam, Lu Zhang, Michael A Kiebish, Kui Yang, Xianlin Han, Richard W Gross, and Jeffrey Chuang

    Link

    Strain-specific variations in cation content and transport in mouse erythrocytes., Alicia Rivera, Robert Y L Zee, Seth L Alper, Luanne L. Peters, and Carlo Brugnara

    Link

    Suppression of SHP-1 promotes corticospinal tract sprouting and functional recovery after brain injury., T Tanaka, Y Fujita, M Ueno, Leonard D. Shultz, and T Yamashita

     

    Surgical Methods for Full-Thickness Skin Grafts to Induce Alopecia Areata in C3H/HeJ Mice., Kathleen A. Silva and John P. Sundberg

    Link

    Survey of common eye diseases in laboratory mouse strains., Bo Chang, Ronald E. Hurd, Jieping Wang, and Patsy M. Nishina

    Link

    Systematic measurement of transcription factor-DNA interactions by targeted mass spectrometry identifies candidate gene regulatory proteins., Hamid Mirzaei, Theo A Knijnenburg, Bong Kim, Max Robinson, Paola Picotti, Gregory W. Carter, Song Li, David J Dilworth, Jimmy K Eng, John D Aitchison, Ilya Shmulevich, Timothy Galitski, Ruedi Aebersold, and Jeffrey Ranish

    Link

    Systems scale interactive exploration reveals quantitative and qualitative differences in response to influenza and pneumococcal vaccines., Gerlinde Obermoser, Scott Presnell, Kelly Domico, Hui Xu, Yuanyuan Wang, Esperanza Anguiano, Luann Thompson-Snipes, Rajaram Ranganathan, Brad Zeitner, Anna Bjork, David Anderson, Cate Speake, Emily Ruchaud, Jason Skinner, Laia Alsina, Mamta Sharma, Helene Dutartre, Alma Cepika, Elisabeth Israelsson, Phuong Nguyen, Quynh-Anh Nguyen, A Carson Harrod, Sandra M Zurawski, Virginia Pascual, Hideki Ueno, Gerald T Nepom, Charlie Quinn, Derek Blankenship, Karolina Palucka, Jacques Banchereau, and Damien Chaussabel

    Link

    Ten quick tips for using the gene ontology., Judith A. Blake

    Link

    The case for genetic monitoring of mice and rats used in biomedical research., James R. Fahey, Hideki Katoh, Rachel Malcolm, and Ana V Perez

    Link

    The Cinderella Effect: Searching for the Best Fit between Mouse Models and Human Diseases., John P. Sundberg, Derry C. Roopenian, Edison Liu, and Paul N Schofield

    Link

    The draft genome of sweet orange (Citrus sinensis)., Qiang Xu, Ling-Ling Chen, Xiaoan Ruan, Dijun Chen, Andan Zhu, Chunli Chen, Denis Bertrand, Wen-Biao Jiao, Bao-Hai Hao, Matthew P Lyon, Jiongjiong Chen, Song Gao, Feng Xing, Hong Lan, Ji-Wei Chang, Xianhong Ge, Yang Lei, Qun Hu, Yin Miao, Lun Wang, Shixin Xiao, Manosh Kumar Biswas, Wenfang Zeng, Fei Guo, Hongbo Cao, Xiaoming Yang, Xi-Wen Xu, Yun-Jiang Cheng, Juan Xu, Ji-Hong Liu, Oscar Junhong Luo, Zhonghui Tang, Wen-Wu Guo, Hanhui Kuang, Hong-Yu Zhang, Mikeal L Roose, Niranjan Nagarajan, Xiu-Xin Deng, and Yijun Ruan

    Link

    The field of bioinformatics. Preface., Elissa J Chesler and Melissa A Haendel

     

    The immunologic functions of the neonatal Fc receptor for IgG., Timo Rath, Timothy T Kuo, Kristi Baker, Shuo-Wang Qiao, Kanna Kobayashi, Masaru Yoshida, Derry C. Roopenian, Edda Fiebiger, Wayne I Lencer, and Richard S Blumberg

    Link

    The importance of the intracortical canal network for murine bone mechanics., Philipp Schneider, Romain Voide, Marco Stampanoni, Leah Rae Donahue, and Ralph Müller

    Link

    The mouse genome database: genotypes, phenotypes, and models of human disease., Carol J. Bult, Janan T. Eppig, Judith A. Blake, James A. Kadin, Joel E Richardson, and Mouse Genome Database Group

    Link

    The mouse pathology ontology, MPATH; structure and applications., Paul N Schofield, John P. Sundberg, Beth A. Sundberg, Colin McKerlie, and Georgios V Gkoutos

    Link

    The perfect host: a mouse host embryo facilitating more efficient germ line transmission of genetically modified embryonic stem cells., Robert A. Taft, Benjamin E. Low, Shannon L. Byers, Stephen A. Murray, Peter Kutny, and Michael V. Wiles

    Link

    The role of mouse strain differences in the susceptibility to fibrosis: a systematic review., Louise Walkin, Sarah E Herrick, Angela Summers, Paul E Brenchley, Catherine M Hoff, Ron Korstanje, and Peter J Margetts

     

    The scat mouse model highlights RASA3, a GTPase activating protein, as a key regulator of vertebrate erythropoiesis and megakaryopoiesis., Luanne L. Peters, Barry H Paw, and Lionel Blanc

    Link

    The Vertebrate Trait Ontology: a controlled vocabulary for the annotation of trait data across species., Carissa A Park, Susan M. Bello, Cynthia Smith, Zhi-Liang Hu, Diane H Munzenmaier, Rajni Nigam, Jennifer R Smith, Mary Shimoyama, Janan T. Eppig, and James M Reecy

    Link

    The zebrafish reference genome sequence and its relationship to the human genome., Kerstin Howe, Matthew D Clark, Carlos F Torroja, James Torrance, Camille Berthelot, Matthieu Muffato, John E Collins, Sean Humphray, Karen McLaren, Lucy Matthews, Stuart McLaren, Ian Sealy, Mario Caccamo, Carol Churcher, Carol Scott, Jeffrey C Barrett, Romke Koch, Gerd-Jörg Rauch, Simon White, William Chow, Britt Kilian, Leonor T Quintais, José A Guerra-Assunção, Yi Zhou, Yong Gu, Jennifer Yen, Jan-Hinnerk Vogel, Tina Eyre, Seth Redmond, Ruby Banerjee, Jianxiang Chi, Beiyuan Fu, Elizabeth Langley, Sean F Maguire, Gavin K Laird, David Lloyd, Emma Kenyon, Sarah Donaldson, Harminder Sehra, Jeff Almeida-King, Jane Loveland, Stephen Trevanion, Matt Jones, Mike Quail, Dave Willey, Adrienne Hunt, John Burton, Sarah Sims, Kirsten McLay, Bob Plumb, Joy Davis, Chris Clee, Karen Oliver, Richard Clark, Clare Riddle, David Eliott, Glen Threadgold, Glenn Harden, Darren Ware, Beverly Mortimer, Giselle Kerry, Paul Heath, Benjamin Phillimore, Alan Tracey, Nicole Corby, Matthew Dunn, Christopher Johnson, Jonathan Wood, Susan Clark, Sarah Pelan, Guy Griffiths, Michelle Smith, Rebecca Glithero, Philip Howden, Nicholas Barker, Christopher Stevens, Joanna Harley, Karen Holt, Georgios Panagiotidis, Jamieson Lovell, Helen Beasley, Carl Henderson, Daria Gordon, Katherine Auger, Deborah Wright, Joanna Collins, Claire Raisen, Lauren Dyer, Kenric Leung, Lauren Robertson, Kirsty Ambridge, Daniel Leongamornlert, Sarah McGuire, Ruth Gilderthorp, Coline Griffiths, Deepa Manthravadi, Sarah Nichol, Gary Barker, Siobhan Whitehead, Michael Kay, Jacqueline Brown, Clare Murnane, Emma Gray, Matthew Humphries, Neil Sycamore, Darren Barker, David Saunders, Justene Wallis, Anne Babbage, Sian Hammond, Maryam Mashreghi-Mohammadi, Lucy Barr, Sancha Martin, Paul Wray, Andrew Ellington, Nicholas Matthews, Matthew Ellwood, Rebecca Woodmansey, Graham Clark, James Cooper, Anthony Tromans, Darren Grafham, Carl Skuce, Richard Pandian, Robert Andrews, Elliot Harrison, Andrew Kimberley, Jane Garnett, Nigel Fosker, Rebekah Hall, Patrick Garner, Daniel Kelly, Christine Bird, Sophie Palmer, Ines Gehring, Andrea Berger, Christopher M Dooley, Zübeyde Ersan-Ürün, Cigdem Eser, Horst Geiger, Maria Geisler, Lena Karotki, Anette Kirn, Judith Konantz, Martina Konantz, Martina Oberländer, Silke Rudolph-Geiger, Mathias Teucke, Kazutoyo Osoegawa, Baoli Zhu, Amanda Rapp, Sara Widaa, Cordelia Langford, Fengtang Yang, Nigel P Carter, Jennifer Harrow, Zemin Ning, Javier Herrero, Steve M J Searle, Anton Enright, Robert Geisler, Ronald H A Plasterk, Charles Lee, Monte Westerfield, Pieter J de Jong, Leonard I Zon, John H Postlethwait, Christiane Nüsslein-Volhard, Tim J P Hubbard, Hugues Roest Crollius, Jane Rogers, and Derek L Stemple

    Link

    Through the glass darkly: intraepithelial neoplasia, top-down differentiation and the road to ovarian cancer., Christopher P Crum, Michael Herfs, Gang Ning, Jonathan G Bijron, Brooke E Howitt, Cynthia A Jimenez, Suchanan Hanamornroongruang, Frank D. McKeon, and Wa Xian

     

    TiF1-gamma plays an essential role in murine hematopoiesis and regulates transcriptional elongation of erythroid genes., Xiaoying Bai, Jennifer J. Trowbridge, Elizabeth Riley, Joseph A Lee, Anthony DiBiase, Vesa M Kaartinen, Stuart H Orkin, and Leonard I Zon

    Link

    TMHS is an integral component of the mechanotransduction machinery of cochlear hair cells., Wei Xiong, Nicolas Grillet, Heather M Elledge, Thomas F J Wagner, Bo Zhao, Kenneth R. Johnson, Piotr Kazmierczak, and Ulrich Müller

    Link

    Transcriptional blood signatures distinguish pulmonary tuberculosis, pulmonary sarcoidosis, pneumonias and lung cancers., Chloe I Bloom, Christine M Graham, Matthew P R Berry, Fotini Rozakeas, Paul S Redford, Yuanyuan Wang, Zhaohui Xu, Katalin A Wilkinson, Robert J Wilkinson, Yvonne Kendrick, Gilles Devouassoux, Tristan Ferry, Makoto Miyara, Diane Bouvry, Valeyre Dominique, Guy Gorochov, Derek Blankenship, Mitra Saadatian, Phillip Vanhems, Huw Beynon, Rama Vancheeswaran, Melissa Wickremasinghe, Damien Chaussabel, Jacques Banchereau, Virginia Pascual, Ling-Pei Ho, Marc Lipman, and Anne O'Garra

    Link

    Transcriptional enhancers in protein-coding exons of vertebrate developmental genes., Deborah I Ritter, Zhiqiang Dong, Su Guo, and Jeffrey Chuang

     

    Transformations for cDNA microarray data., Xiangqin Cui, M Kathleen Kerr, and Gary Churchill

    Link

    Transforming growth factor β-induced peritoneal fibrosis is mouse strain dependent., Peter J Margetts, Catherine Hoff, Limin Liu, Ron Korstanje, Louise Walkin, Angela Summers, Sarah Herrick, and Paul Brenchley

    Link

    t-SNARE Syntaxin2 (STX2) Is Implicated in Intracellular Transport of Sulfoglycolipids During Meiotic Prophase in Mouse Spermatogenesis., Yasuhiro Fujiwara, Narumi Ogonuki, Kimiko Inoue, Atsuo Ogura, Mary Ann Handel, Junko Noguchi, and Tetsuo Kunieda

    Link

    Tumor suppression: Putting p53 in context., Kevin D. Mills

     

    Tumor-targeting multifunctional micelles for imaging and chemotherapy of advanced bladder cancer., Tzu-Yin Lin, Yuan-Pei Li, Hongyong Zhang, Juntao Luo, Neal C. Goodwin, Tingjuan Gao, Ralph de Vere White, Kit S Lam, and Chong-Xian Pan

    Link

    Use of pleiotropy to model genetic interactions in a population., Gregory W Carter, Michelle Hays, Amir Sherman, and Timothy Galitski

     

    Use of the expanded panel of BXD mice narrow QTL regions in ethanol-induced locomotor activation and motor incoordination., Candis S DuBose, Elissa J Chesler, Dan Goldowitz, and Kristin M Hamre

    Link

    Using chimaeric expression sequence tag as the reference to identify three-dimensional chromosome contacts., Songling Li and Dieter W Heermann

    Link

    Variations in COL15A1 and COL18A1 influence age of onset of primary open angle glaucoma., J L Wiggs, Gareth R. Howell, K Linkroum, W Abdrabou, E Hodges, Catherine E. Braine, L R Pasquale, G J Hannon, J L Haines, and Simon W M John

    Link

    What causes alopecia areata?, K J McElwee, A Gilhar, D J Tobin, Y Ramot, John P. Sundberg, M Nakamura, M Bertolini, S Inui, Y Tokura, L E King, B Duque-Estrada, A Tosti, A Keren, S Itami, Y Shoenfeld, A Zlotogorski, R Paus, Bruna Duque-Estrada, Antonella Tosti, Kevin J McElwee, Amos Gilhar, Aviad Keren, Marta Bertolini, Yehuda Shoenfeld, Motonobu Nakamura, Yoshiki Tokura, John P Sundberg, Lloyd E King, Yuval Ramot, Abraham Zlotogorski, Desmond J Tobin, Ralf Paus, Shigeki Inui, and Satoshi Itami

    Link

    Whole-genome reconstruction and mutational signatures in gastric cancer., Niranjan Nagarajan, Denis Bertrand, Axel M Hillmer, Zhi Jiang Zang, Fei Yao, Pierre-Étienne Jacques, Audrey Sm Teo, Ioana Cutcutache, Zhenshui Zhang, Wah Heng Lee, Yee Yen Sia, Song Gao, Pramila N Ariyaratne, Andrea Ho, Xing Yi Woo, Lavanya Veeravali, Choon Kiat Ong, Niantao Deng, Kartiki V Desai, Chiea Chuen Khor, Martin L Hibberd, Atif Shahab, Jaideepraj Rao, Mengchu Wu, Ming Teh, Feng Zhu, Sze Yung Chin, Brendan Pang, Jimmy By So, Guillaume Bourque, Richie Soong, Wing-Kin Sung, Bin Tean Teh, Steven Rozen, Xiaoan Ruan, Khay Guan Yeoh, Patrick Bo Tan, and Yijun Ruan

    Link

    Wnt3a activates dormant c-Kit(-) bone marrow-derived cells with short-term multilineage hematopoietic reconstitution capacity., Jennifer J. Trowbridge, Borhane Guezguez, Randall T Moon, and Mickie Bhatia

     

    Young and old genetically heterogeneous HET3 mice on a rapamycin diet are glucose intolerant but insulin sensitive., Dudley W Lamming, Lan Ye, Clinton M. Astle, Joseph A Baur, David M Sabatini, and David E. Harrison

    Link

    Zinc finger proteins and the 3D organization of chromosomes., Christoph J Feinauer, Andreas Hofmann, Sebastian Goldt, Lei Liu, Gabriell Máté, and Dieter W Heermann

    Link

    β-Actin and fascin-2 cooperate to maintain stereocilia length., Benjamin J Perrin, Dana M Strandjord, Praveena Narayanan, Davin M Henderson, Kenneth R. Johnson, and James M Ervasti

 
 
 

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