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    Content Posted in 2025

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    1937 Annual Report, The Jackson Laboratory

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    1938 Annual Report, The Jackson Laboratory

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    1939 Annual Report, The Jackson Laboratory

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    1940 Annual Report, The Jackson Laboratory

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    1941 Annual Report, The Jackson Laboratory

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    1942 Annual Report, The Jackson Laboratory

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    1943 Annual Report, The Jackson Laboratory

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    1944 Annual Report, The Jackson Laboratory

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    1945 Annual Report, The Jackson Laboratory

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    1946 Annual Report, The Jackson Laboratory

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    1947-1948 Annual Report, The Jackson Laboratory

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    1949-1950 Annual Report, The Jackson Laboratory

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    1950-1951 Annual Report, The Jackson Laboratory

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    1951-1952 Annual Report, The Jackson Laboratory

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    1952-1953 Annual Report, The Jackson Laboratory

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    1953-1954 Annual Report, The Jackson Laboratory

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    1954-1955 Annual Report, The Jackson Laboratory

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    1955-1956 Annual Report, The Jackson Laboratory

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    1956-1957 Annual Report, The Jackson Laboratory

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    1957-1958 Annual Report, The Jackson Laboratory

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    1958-1959 Annual Report, The Jackson Laboratory

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    1959-1960 Annual Report, The Jackson Laboratory

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    1960-1961 Annual Report, The Jackson Laboratory

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    1961-1962 Annual Report, The Jackson Laboratory

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    1962-1963 Annual Report, The Jackson Laboratory

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    1963-1964 Annual Report, The Jackson Laboratory

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    1964-1965 Annual Report, The Jackson Laboratory

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    1965-1966 Annual Report, The Jackson Laboratory

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    1966-1967 Annual Report, The Jackson Laboratory

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    1967-1968 Annual Report, The Jackson Laboratory

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    1968-1969 Annual Report, The Jackson Laboratory

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    1969-1970 Annual Report, The Jackson Laboratory

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    1970-1971 Annual Report, The Jackson Laboratory

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    1971-1972 Annual Report, The Jackson Laboratory

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    1972-1973 Annual Report, The Jackson Laboratory

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    1973-1974 Annual Report, The Jackson Laboratory

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    1974-1975 Annual Report, The Jackson Laboratory

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    1975-1976 Annual Report, The Jackson Laboratory

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    1976-1977 Annual Report, The Jackson Laboratory

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    1977-1978 Annual Report, The Jackson Laboratory

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    1978-1979 Annual Report, The Jackson Laboratory

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    1979-1980 Annual Report, The Jackson Laboratory

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    1980-1981 Annual Report, The Jackson Laboratory

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    1981-1982 Annual Report, The Jackson Laboratory

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    1982-1983 Annual Report, The Jackson Laboratory

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    1983-1984 Annual Report, The Jackson Laboratory

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    1984-1985 Annual Report, The Jackson Laboratory

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    1985-1986 Annual Report, The Jackson Laboratory

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    1985-1986 Scientific Report, The Jackson Laboratory

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    1986-1987 Scientific Report, The Jackson Laboratory

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    1987-1988 Scientific Report, The Jackson Laboratory

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    1987 Annual Report, The Jackson Laboratory

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    1988-1989 Scientific Report, The Jackson Laboratory

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    1988 Annual Report, The Jackson Laboratory

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    1989-1990 Scientific Report, The Jackson Laboratory

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    1989 Annual Report, The Jackson Laboratory

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    1990-1991 Scientific Report, The Jackson Laboratory

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    1990 Annual Report, The Jackson Laboratory

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    1991-1992 Scientific Report, The Jackson Laboratory

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    1991 Annual Report, The Jackson Laboratory

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    1992 Annual Report, The Jackson Laboratory

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    1993 Annual Report, The Jackson Laboratory

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    1993 Scientific Report, The Jackson Laboratory

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    1994 Annual Report, The Jackson Laboratory

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    1994 Scientific Report, The Jackson Laboratory

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    1995-1996 Scientific Report, The Jackson Laboratory

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    1995 Annual Report, The Jackson Laboratory

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    1996-1997 Scientific Report, The Jackson Laboratory

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    1996 Annual Report, The Jackson Laboratory

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    1997-1998 Scientific Report, The Jackson Laboratory

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    1997 Annual Report, The Jackson Laboratory

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    1998-1999 Scientific Report, The Jackson Laboratory

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    1998 Annual Report, The Jackson Laboratory

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    1999-2000 Scientific Report, The Jackson Laboratory

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    1999 Annual Report, The Jackson Laboratory

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    2000-2001 Scientific Report, The Jackson Laboratory

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    2000 Annual Report, The Jackson Laboratory

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    2001-2002 Scientific Report, The Jackson Laboratory

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    2001 Annual Report, The Jackson Laboratory

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    2002-2003 Scientific Report, The Jackson Laboratory

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    2002 Annual Report, The Jackson Laboratory

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    2003-2004 Scientific Report, The Jackson Laboratory

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    2004-2005 Scientific Report, The Jackson Laboratory

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    2005-2006 Scientific Report, The Jackson Laboratory

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    2006 Annual Report, The Jackson Laboratory

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    A biometric survey of known and prospective murine models of posterior microphthalmia-nanophthalmia., Navdeep Gogna, Jai Pinkney, Lisa Stone, Mhd Mustafa Khorzom, Fuxin Zhao, Gayle B. Collin, Juergen K. Naggert, Mark P. Krebs, and Patsy M. Nishina

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    A brief chronicle of research on human pluripotent stem cells., Martin Pera

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    Absence of Glaucoma in Tg-MYOCY437H Mice of Diverse Genetic Backgrounds., Nicholas G Tolman, Marina Simón, Felicia A Juarez, Chi Zhang, Zhivka I Hristova, Tionna Ouellette, Michael A Sellarole, Wilhelmine N deVries, Christa Montgomery, and Simon W M John

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    A call to action for deciphering genetic variants in human pluripotent stem cells for cell therapy., Nissim Benvenisty, Jonathan S Draper, Paul J Gokhale, Lyn Healy, Zoe Hewitt, Deborah Hursh, Adam Hodgson, Tenneille E Ludwig, Nancy Mah, Sarah E McClelland, Milena Mennecozzi, Florian T Merkle, Joanne C Mountford, Martin Pera, Alessandro Prigione, Tristan A Rodriguez, Andrea Rossi, Foad J Rouhani, Kourosh Saeb-Parsy, Lucia Selfa Aspiroz, Nika Shakiba, Claudia Spits, Peter D Tonge, and Ivana Barbaric

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    Accreditation Council for Genetic Counseling Board of Directors Response to Myers et al 'A report of the AGCPD task force to evaluate associations between select admissions requirements, demographics, and performance on ABGC certification examination', Molly A. McGinniss, Susan Randall Armel, Sylvia Mann, Erin P. Carmany, Heather Creswick, Sarah B. McBrien, Kate Reed, Jennifer N. Eichmeyer, and Dawn C. Allain

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    A community effort for COVID-19 Ontology Harmonization, Asiyah Yu Lin, Yuki Yamagata, William D. Duncan, Leigh Carmody, Tatsuya Kushida, Hiroshi Masuya, John Beverley, Biswanath Dutta, Michael DeBellis, Zoë May Pendlington, Paola Roncaglia, and Yongqun He

     

    A comparative biometric analysis indicates Clqtn/5 plays a role in ocular growth, MHD Mustafa Khorzom

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    A compendium of human gene functions derived from evolutionary modelling., Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Anushya Muruganujan, Suzanna E Lewis, Dustin Ebert, Tremayne Mushayahama, Gene Ontology Consortium, and Paul D Thomas

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    A comprehensive atlas of AAV tropism in the mouse., Christopher J Walkey, Kathy J. Snow, Jote Bulcha, Aaron R Cox, Alexa E Martinez, M Cecilia Ljungberg, Denise G Lanza, Marco De Giorgi, Marcel A Chuecos, Michele Alves-Bezerra, Carlos Flores Suarez, Sean M Hartig, Susan G Hilsenbeck, Chih-Wei Hsu, Ethan Saville, Yaned Gaitan, Jeff Duryea, Seth Hannigan, Mary E Dickinson, Oleg Mirochnitchenko, Dan Wang, Cathleen Lutz, Jason D Heaney, Guangping Gao, Stephen A Murray, and William R Lagor

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    A Concordance Study among 26 NGS Laboratories Participating in the NCI Molecular Analysis for Therapy Choice Clinical Trial., Linda K Zane, Laura M Yee, Ting-Chia Chang, Jeffrey Sklar, Guangxiao Yang, Jia Di Wen, Peining Li, Robin Harrington, David J Sims, Kneshay Harper, Jeffrey M Trent, Janine R LoBello, Szabolcs Szelinger, Kasey Benson, Jia Zeng, Kelsey Poorman, Danbin Xu, Garrett M Frampton, Dean C Pavlick, Vincent A Miller, Bevan Tandon, Wojciech Swat, Lawrence Weiss, Vincent Anthony Funari, Jeffrey M Conroy, James L Prescott, Pranil K Chandra, Charles Ma, Kristen J Champion, Gregory X Baschkopf, Yuri A Fesko, Tracey Allen K Freitas, Scott A Tomlins, Daniel H Hovelson, Kevin White, Shelly Sorrells, Robert Tell, Nike Beaubier, David King, Lei Li, Kevin Kelly, Jasmina Uvalic, Bridgette Meyers, Ravindra Kolhe, Neal I Lindeman, Michele Baltay, Lynette M Sholl, Jean Lopategui, Eric Vail, Wenjuan Zhang, Milhan Telatar, Michelle Afkhami, Susan J Hsiao, Mahesh M Mansukhani, Emily Adams, LiQun Jiang, for the NCI-MATCH Designated Laboratories, Kenneth D Aldape, Mark Raffeld, Liqiang Xi, for NCI-COMPASS Team, Henning Stehr, Jeremy P Segal, Dara L Aisner, Kurtis D Davies, Noah A Brown, Robert J Livingston, Eric Q Konnick, Wei Song, James P Solomon, Zenta Walther, for NCI-MATCH Designated Laboratories, Lisa M McShane, Lyndsay N Harris, Alice P Chen, Gregory J Tsongalis, Stanley R Hamilton, Keith T Flaherty, Peter J O'Dwyer, Barbara A Conley, David R Patton, A John Iafrate, P Mickey Williams, James V Tricoli, and Chris Karlovich

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    A consensus guide to preclinical indirect calorimetry experiments., Alexander S Banks, David B Allison, Thierry Alquier, Ansarullah, Steven N Austad, Johan Auwerx, Julio E Ayala, Joseph A Baur, Stefania Carobbio, Gary Churchill, Morten Dall, Rafael de Cabo, Jose Donato, Nathalia R V Dragano, Carol F Elias, Anthony W Ferrante, Brian N Finck, Jose E Galgani, Zachary Gerhart-Hines, Laurie J Goodyear, Justin L Grobe, Rana K Gupta, Kirk M Habegger, Sean M Hartig, Andrea L Hevener, Steven B Heymsfield, Corey D Holman, Martin Hrabě de Angelis, David E James, Lawrence Kazak, Jae Bum Kim, Martin Klingenspor, Xingxing Kong, Sander Kooijman, Louise Lantier, K C Kent Lloyd, James C Lo, Irfan J Lodhi, Paul S MacLean, Owen P McGuinness, Gema Medina-Gómez, Raghavendra G Mirmira, Christopher D Morrison, Gregory J Morton, Timo D Müller, Yoshihiro Ogawa, David Pajuelo-Reguera, Matthew J Potthoff, Nathan Qi, Marc L Reitman, Patrick C N Rensen, Jan Rozman, Jennifer M Rutkowsky, Kei Sakamoto, Philipp E Scherer, Gary J Schwartz, Radislav Sedlacek, Mohammed Selloum, Saame Raza Shaikh, Shuai Chen, Gerald I Shulman, Vojtěch Škop, Alexander A Soukas, John R Speakman, Bruce M Spiegelman, Gregory R Steinberg, Katrin J Svensson, John P Thyfault, Tony Tiganis, Paul M Titchenell, Nigel Turner, Licio A Velloso, Antonio Vidal-Puig, Christopher S Ward, Ashley S Williams, Christian Wolfrum, Allison W Xu, Ying Xu, Juleen R Zierath, and The International Indirect Calorimetry Consensus Committee (IICCC

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    A corpus of GA4GH phenopackets: Case-level phenotyping for genomic diagnostics and discovery., Daniel Danis, Michael J Bamshad, Yasemin Bridges, Andrés Caballero-Oteyza, Pilar Cacheiro, Leigh Carmody, Leonardo Chimirri, Jessica X Chong, Ben D Coleman, Raymond Dalgleish, Peter J Freeman, Adam S L Graefe, Tudor Groza, Peter Hansen, Julius O B Jacobsen, Adam Klocperk, Maaike Kusters, Markus S Ladewig, Allison J Marcello, Teresa Mattina, Christopher J Mungall, Monica C Munoz-Torres, Justin T Reese, Filip Rehburg, Bárbara C S Reis, Catharina Schuetz, Damian Smedley, Timmy Strauss, Jagadish Chandrabose Sundaramurthi, Sylvia Thun, Kyran Wissink, John F Wagstaff, David Zocche, Melissa A Haendel, and Peter N Robinson

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    Activin E is a new guardian protecting against hepatic steatosis via inhibiting lipolysis in white adipose tissue., Shi-Young Park, Yoonil Cho, Sae-Mi Son, Jang Ho Hur, Yeongmin Kim, Hyunhee Oh, Hui-Young Lee, Sungwon Jung, Sanghee Park, Il-Young Kim, Se-Jin Lee, and Cheol Soo Choi

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    Advances in Animal Models and Cutting-Edge Research in Alternatives: Proceedings of the Second International Conference on 3Rs Research and Progress, Hyderabad, 2021, Akshay Sonawane, Bharadwaja Vadloori, Suresh Poosala, Helena Kandarova, Mandar Kulkarni, Adedamola Olayanju, Tuli Dey, Uday Saxena, Lena Smirnova, Yasunari Kanda, Jaganmohan Reddy, Subhadra Dravida, Saikat Biswas, Mathieu Vinken, Montip Gettayacamin, Arti Ahluwalia, Franco Mondini, Somshuvra Bhattacharya, Pushkar Kulkarni, Kirsten Rosenmay Jacobsen, Subrahmanyam Vangala, and Ana Luiza Mill√°s

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    A feasibility study of enzymatic methylation sequencing of cell-free DNA from cerebrospinal fluid of pediatric central nervous system tumor patients for molecular classification., Aaron M Taylor, Jody T Lombardi, Areeba Patel, Ariella Tamariz, Jonathan Martin, Markus J Bookland, David S Hersh, Evan Cantor, Xianyuan Song, Felix Sahm, Patrick Ks Ng, Joanna J Gell, and Ching C Lau

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    A framework for sharing of clinical and genetic data for precision medicine applications., Ahmed Elhussein, Ulugbek Baymuradov, NYGC ALS Consortium, Noémie Elhadad, Karthik Natarajan, and Gamze Gürsoy

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    A Framework for Strengthening The Quantitative Skills/Reasoning Support Ecosystem at Small Liberal Arts Colleges, Laura J. Muller and Melissa Eblen-Zayas

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    AI-driven multi-omics modeling of myalgic encephalomyelitis/chronic fatigue syndrome., Ruoyun Xiong, Elizabeth Aiken, Ryan Caldwell, Suzanne D Vernon, Lina Kozhaya, Courtney Gunter, Lucinda Bateman, Derya Unutmaz, and Julia Oh

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    AI-driven multi-omics modeling of myalgic encephalomyelitis/chronic fatigue syndrome., Ruoyun Xiong, Elizabeth Aiken, Ryan Caldwell, Suzanne D Vernon, Lina Kozhaya, Courtney Gunter, Lucinda Bateman, Derya Unutmaz, and Julia Oh

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    AI-driven multi-omics modeling of myalgic encephalomyelitis/chronic fatigue syndrome., Ruoyun Xiong, Elizabeth Aiken, Ryan Caldwell, Suzanne D Vernon, Lina Kozhaya, Courtney Gunter, Lucinda Bateman, Derya Unutmaz, and Julia Oh

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    A longitudinal and cross-sectional study of plasma neurofilament light chain concentration in Charcot-Marie-Tooth disease, Alexander Martin Rossor, Mahima Kapoor, Henny Wellington, Emily L Spaulding, James N. Sleigh, Robert W. Burgess, Matilde Laura, Henrik Zetterberg, Alexa Bacha, Xingyao Wu, Amanda Heslegrave, Michael E. Shy, and Mary M. Reilly

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    Alpha-smooth muscle actin-expressing dermal sheath cells are a major cellular contributor to heterotopic subcutaneous ossifications in a mouse model of Albright hereditary osteodystrophy., Patrick McMullan, Peter Maye, Sierra H Root, Qingfen Yang, Sarah Edie, David Rowe, Ivo Kalajzic, and Emily L Germain-Lee

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    Alternating hemiplegia of childhood associated mutations in Atp1a3 reveal diverse neurological alterations in mice., Markus Terrey, Georgii Krivoshein, Scott I Adamson, Elena Arystarkhova, Laura C. Anderson, John Szwec, Shelby McKee, Holly Jones, Sara Perkins, Vijay Selvam, Pierre-Alexandre Piec, Dweet Chhaya, Ari Dehn, Aamir Zuberi, Stephen A Murray, Natalia S Morsci, Kathleen J Sweadner, David A Knowles, Else A Tolner, Arn M J M van den Maagdenberg, and Cathleen Lutz

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    Alternative splicing is coupled to gene expression in a subset of variably expressed genes., Guy Karlebach, Robin Steinhaus, Daniel Danis, Maeva Devoucoux, Olga Anczuków, Gloria Sheynkman, Dominik Seelow, and Peter N Robinson

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    Alternative splicing of transposable elements in human breast cancer., Alex V Nesta, Diogo F T Veiga, Jacques Banchereau, Olga Anczuków, and Christine R Beck

     

    Alzheimer's age-dependent molecular signatures in individuals with the loss of function CETP I405V variant, Isshori Gurung

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    A Multimodal Therapeutic Strategy for Inflammatory Bowel Disease Using MicroRNA-146a Mimic Encapsulated in Lipid Nanoparticles., Kanika Suri, Vishnu Hosur, Rohit Panchakshari, and Mansoor M Amiji

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    Amyotrophic lateral sclerosis and frontotemporal dementia mutation reduces endothelial TDP-43 and causes blood-brain barrier defects., Ashok Cheemala, Amy L Kimble, Emily N Burrage, Stephen B Helming, Jordan D Tyburski, Nathan K Leclair, Omar M Omar, Aamir Zuberi, Melissa Murphy, Evan R Jellison, Bo Reese, Xiangyou Hu, Cathleen Lutz, Riqiang Yan, and Patrick A Murphy

     

    Analysis of Bimanual Motor Task Function in the Mouse Model After Ischemic Stroke Utilizing Deep-Learning Model DeepEthogram, Olivia S. Jung

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    Analysis of CNS autoimmunity in genetically diverse mice reveals unique phenotypes and mechanisms., Emily A Nelson, Anna L. Tyler, Taylor Lakusta-Wong, Karolyn G Lahue, Katherine C Hankes, Cory Teuscher, Rachel M Lynch, Martin T Ferris, J Matthew Mahoney, and Dimitry N Krementsov

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    Analysis of functional connectivity changes from childhood to old age: A study using HCP-D, HCP-YA, and HCP-A datasets., Yaotian Wang, Shuoran Li, Jie He, Lingyi Peng, Qiaochu Wang, Xu Zou, Dana L Tudorascu, David J Schaeffer, Lauren Schaeffer, Diego Szczupak, Jung Eun Park, Stacey J Sukoff Rizzo, Gregory W. Carter, Afonso C Silva, and Tingting Zhang

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    Analysis of lifespan across diversity outbred mouse studies identifies multiple longevity-associated loci., Martin N Mullis, Kevin M Wright, Anil Raj, Daniel M Gatti, Peter C. Reifsnyder, Kevin Flurkey, Jonathan R Archer, Laura Robinson, Andrea Di Francesco, Karen L. Svenson, Ron Korstanje, David E Harrison, J Graham Ruby, and Gary Churchill

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    Anapc5 and Anapc7 as genetic modifiers of KIF18A function in fertility and mitotic progression., Carleigh Nesbit, Whitney Martin, Anne M Czechanski, Candice Byers, Narayanan Raghupathy, Ardian Ferraj, Jason Stumpff, and Laura G Reinholdt

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    An epithelial cell culture model for sturgeon integument responds sensitively to 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure., Sumi Nechat, Melina Shadi, Andrea D Schreier, Nann A Fangue, John P Sundberg, and Robert H Rice

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    A New Targeted Transgenic Mouse Line for the Study of Protocadherin γC4., Cathy M McLeod, Camille M Hanes, Leah C Fuller, Samjhana Bhandari, Hannah G Lanthier, Robert W. Burgess, Joshua A Weiner, and Andrew M Garrett

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    An integrative TAD catalog in lymphoblastoid cell lines discloses the functional impact of deletions and insertions in human genomes., Chong Li, Marc Jan Bonder, Sabriya Syed, Matthew Jensen, Human Genome Structural Variation Consortium (HGSVC), HGSVC Functional Analysis Working Group, Mark B Gerstein, Michael C Zody, Mark J P Chaisson, Michael E Talkowski, Tobias Marschall, Jan O Korbel, Evan E Eichler, Charles Lee, and Xinghua Shi

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    An international perspective on the future of systemic sclerosis research., David J Abraham, Carol M Black, Christopher P Denton, Jörg H W Distler, Robyn Domsic, Carol Feghali-Bostwick, Pravitt Gourh, Monique Hinchcliff, Fred Kolling, Masataka Kuwana, Robert Lafyatis, Ulf Landegren, J Matthew Mahoney, Javier Martin, Marco Matucci-Cerinic, Zsuzsanna H McMahan, Ana L Mora, Luc Mouthon, Marlene Rabinovitch, Mauricio Rojas, Kristofer Rubin, Maria Trojanowska, John Varga, Michael L Whitfield, Armando Gabrielli, and Thomas Krieg

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    An intranasal subunit vaccine induces protective systemic and mucosal antibody immunity against respiratory viruses in mouse models., Aina Karen Anthi, Anette Kolderup, Eline Benno Vaage, Malin Bern, Sopisa Benjakul, Elias Tjärnhage, Fulgencio Ruso-Julve, Kjell-Rune Jensen, Heidrun Elisabeth Lode, Marina Vaysburd, Jeannette Nilsen, Marie Leangen Herigstad, Siri Aastedatter Sakya, Lisa Tietze, Diego Pilati, Mari Nyquist-Andersen, Mirjam Dürkoop, Torleif Tollefsrud Gjølberg, Linghang Peng, Stian Foss, Morten C Moe, Benjamin E. Low, Michael V. Wiles, David Nemazee, Frode L Jahnsen, John Torgils Vaage, Kenneth A Howard, Inger Sandlie, Leo C James, Gunnveig Grødeland, Fridtjof Lund-Johansen, and Jan Terje Andersen

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    An Isoform-Specific RUNX1C-BTG2 Axis Governs AML Quiescence and Chemoresistance., Cuijuan Han, Zhiping Zhang, Edie I Crosse, Sogand Sajedi, Bin Lu, Xiyue Wang, Sadik Karma, Mitchell S. Kostich, Sakthi Harini Rajendran, Dylan B Udy, Steven Chen, Alexander Arnuk, Abimbola Eunice Lawal, Kayla R Koenig, Meryl McKenna, Patrick K Reville, Hussein A Abbas, Omar Abdel-Wahab, Pedro Miura, Robert K Bradley, and Eric Wang

     

    Annotation of Metabolites in Stable Isotope Tracing Untargeted Metabolomics via Khipu-web., Joshua M Mitchell, Yuanye Chi, Shujian Zheng, Maheshwor Thapa, Eric Wang, and Shuzhao Li

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    An ontology-based rare disease common data model harmonising international registries, FHIR, and Phenopackets., Adam S L Graefe, Miriam R Hübner, Filip Rehburg, Steffen Sander, Sophie A I Klopfenstein, Samer Alkarkoukly, Ana Grönke, Annic Weyersberg, Daniel Danis, Jana Zschüntzsch, Elisabeth F Nyoungui, Susanna Wiegand, Peter Kühnen, Peter N Robinson, Oya Beyan, and Sylvia Thun

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    Antisense oligonucleotide-mediated TRA2β poison exon inclusion induces the expression of a lncRNA with anti-tumor effects., Nathan Leclair, Mattia Brugiolo, SungHee Park, Maeva Devoucoux, Laura M Urbanski, Brittany Lynn Angarola, Marina Yurieva, and Olga Anczuków

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    A Protocol for Horizontally Acquired Metabolic Gene Detection in Algae, Ravi S Pandey and Rajeev K. Azad

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    Arginine metabolism is a biomarker of red blood cell and human aging., Julie A Reisz, Eric J Earley, Travis Nemkov, Alicia Key, Daniel Stephenson, Gregory R Keele, Monika Dzieciatkowska, Steven L Spitalnik, Eldad A Hod, Steven Kleinman, Nareg H Roubinian, Mark T Gladwin, Kirk C Hansen, Philip J Norris, Michael P Busch, James C Zimring, Gary Churchill, Grier P Page, and Angelo D'Alessandro

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    Artificial intelligence-based digital pathology using H&E-stained whole slide images in immuno-oncology: from immune biomarker detection to immunotherapy response prediction., Jessica Zhang, Horyun Choi, Yeseul Kim, Jonghanne Park, Sukjoo Cho, Eugene Kim, Allen Cho, Ju Young Lee, Jaeyoun Choi, Christmann Low, Chan Mi Jung, Emma J Yu, Jeffrey Chuang, Lee Cooper, and Young Kwang Chae

     

    Assessing Anxiety Through Defecation Kinetics in BXD Mice, Lucia Zhang

     

    Assessing Immune Subtype Diversity in Mice, Xavier Vesco

     

    Assessing Phasing Accuracy for Inferring Haplotype Structure in Laboratory Marmosets, Adon C. Roy

     

    Assessing the Incidence of Heart Failure with Preserved Ejection Fraction (HFpEF) within the Context of Aging, Silvia Wright

     

    Assessing the Performance of Models from the 2022 RSNA Cervical Spine Fracture Detection Competition at a Level I Trauma Center., Zixuan Hu, Markand Patel, Robyn L Ball, Hui Ming Lin, Luciano M Prevedello, Mitra Naseri, Shobhit Mathur, Robert Moreland, Jefferson Wilson, Christopher Witiw, Kristen W Yeom, Qishen Ha, Darragh Hanley, Selim Seferbekov, Hao Chen, Philipp Singer, Christof Henkel, Pascal Pfeiffer, Ian Pan, Harshit Sheoran, Wuqi Li, Adam E Flanders, Felipe C Kitamura, Tyler Richards, Jason Talbott, Ervin Sejdić, and Errol Colak

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    Assessing the potential relevance of CEACAM6 as a blood transcriptional biomarker., Darawan Rinchai and Damien Chaussabel

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    Assessment of Antimicrobial Therapy in Eradicating Chlamydia muridarum in Research Mice: Immune Status and Its Impact on Outcomes., Michael B Palillo, Sebastian E Carrasco, Noah Mishkin, Jack A Palillo, Denise B Lynch, Samira Lawton, Mert Aydin, Anthony J Mourino, Neil S Lipman, and Rodolfo J Ricart Arbona

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    Association of Neonatal and Maternal Nasal Microbiome Among Neonates in the Intensive Care Unit., Shaoming Xiao, Wei Zhou, Ryan Caldwell, Slade Decker, Julia Oh, and Aaron M Milstone

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    A Survey Study of Roadblocks in Translational Science., Fasiha Kanwal, Christopher I Amos, Katherine H Sippel, Claudia Neuhauser, Ariel Harrison, Mary E Dickinson, Charles Minard, and Bettina M Beech

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    A Systematic Approach to Prioritise Diagnostically Useful Findings for Inclusion in Electronic Health Records as Discrete Data to Improve Clinical Artificial Intelligence Tools and Genomic Research., P Guillod, A Savvas, Peter N Robinson, D Nai, K N Naresh, G Ott, A Schuh, W A Sewell, M Anderson, N Matentzoglu, D Durgavarjhula, M L Xu, M J Druzdzel, and J M Astle

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    A ventilated perfused lung model platform to dissect the response of the lungs to viral infection., I Deniz Derman, Mecit Altan Alioglu, Joseph Christakiran Moses, Zissis C Chroneos, Yasar Ozer Yilmaz, Dishary Banerjee, Jonathan Koff, Syed Hasan Askari Rizvi, Danielle Nicole Klunk, Nazmiye Celik, Sirisha Pochareddy, Todd M Umstead, Ilayda Namli, Sarah E Holton, Carmen Mikacenic, Jessica L Thompson, Diana Cadena, Danielle Reifsnyder Hickey, Momoka Nagamine, Prajakta Warang, Michael Schotsaert, Phylip Chen, Mark E Peeples, Karolina Palucka, and Ibrahim T Ozbolat

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    A ventilated perfused lung model platform to dissect the response of the lungs to viral infection., I Deniz Derman, Mecit Altan Alioglu, Joseph Christakiran Moses, Zissis C Chroneos, Yasar Ozer Yilmaz, Dishary Banerjee, Jonathan Koff, Syed Hasan Askari Rizvi, Danielle Nicole Klunk, Nazmiye Celik, Sirisha Pochareddy, Todd M Umstead, Ilayda Namli, Sarah E Holton, Carmen Mikacenic, Jessica L Thompson, Diana Cadena Castaneda, Danielle Reifsnyder Hickey, Momoka Nagamine, Prajakta Warang, Michael Schotsaert, Phylip Chen, Mark E Peeples, Karolina Palucka, and Ibrahim T Ozbolat

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    A year-long field study of buried plastics reveals underestimation of plastic pollution on Hawaiian beaches., Astrid E Delorme, Olivier Poirion, Laurent Lebreton, Pierre-Yves le Gac, Kimeona Kāne, and Sarah-Jeanne Royer

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    Bacterial Indole as a Multifunctional Regulator of Klebsiella oxytoca Complex Enterotoxicity, Nagender Ledala, Mishika Malik, Karim Rezaul, Sara Paveglio, Anthony Provatas, Aaron Kiel, Melissa Caimano, Yanjiao Zhou, Jonathan Lindgren, Kristyna Krasulova, Peter Illes, Zdenek Dvorak, Sandhya Kortagere, Sabine Kienesberger, Amar Cosic, Lisa Pöltl, Ellen L. Zechner, Subho Ghosh, Sridhar Mani, Justin D. Radolf, and Adam P. Matson

     

    Biallelic EPB41L3 variants underlie a developmental disorder with seizures and myelination defects., Elizabeth A Werren, Guillermo Rodriguez Bey, Purvi Majethia, Parneet Kaur, Siddaramappa J Patil, Minal V Kekatpure, Alexandra Afenjar, Leila Qebibo, Lydie Burglen, Hoda Tomoum, Florence Demurger, Christele Duborg, Shahyan Siddiqui, Yao-Chang Tsan, Uzma Abdullah, Zafar Ali, Saadia Maryam Saadi, Shahid Mahmood Baig, Henry Houlden, Reza Maroofian, Quasar Saleem Padiath, Stephanie L Bielas, and Anju Shukla

     

    Bioassay-Driven, Fractionation-Empowered, Focused Metabolomics for Discovering Bacterial Activators of Aryl Hydrocarbon Receptor., Huidi Tian, Lei Wang, Rachel Hardy, Lina Kozhaya, Lindsey Placek, Elizabeth Fleming, Julia Oh, Derya Unutmaz, and Xudong Yao

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    Biological databases in the age of generative artificial intelligence., Mihai Pop, Teresa K Attwood, Judith A. Blake, Philip E Bourne, Ana Conesa, Terry Gaasterland, Lawrence Hunter, Carl Kingsford, Oliver Kohlbacher, Thomas Lengauer, Scott Markel, Yves Moreau, William S Noble, Christine Orengo, B F Francis Ouellette, Laxmi Parida, Natasa Przulj, Teresa M Przytycka, Shoba Ranganathan, Russell Schwartz, Alfonso Valencia, and Tandy Warnow

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    Biological modifications of the immune response to COVID-19 vaccine in patients treated with rituximab and immune checkpoint inhibitors., Francesco Ravera, Martina Dameri, Isabella Lombardo, Mario Stabile, Pamela Becherini, Neri Fallani, Camilla Scarsi, Benedetta Cigolini, Giusy Gentilcore, Alexander Domnich, Lodovica Zullo, Eugenia Cella, Giulia Francia, Eugenia Montanari, Andrea Orsi, Andrea Bellodi, Fabio Ferrando, Darawan Rinchai, Filippo Ballerini, Bianca Bruzzone, Damien Chaussabel, Jean-Charles Grivel, Carlo Genova, Roberto Massimo Lemoli, Davide Bedognetti, Alberto Ballestrero, Lorenzo Ferrando, and Gabriele Zoppoli

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    CASCADES, a novel SOX2 super-enhancer-associated long noncoding RNA, regulates cancer stem cell specification and differentiation in glioblastoma., Uswa Shahzad, Marina Nikolopoulos, Christopher Li, Michael Johnston, Jenny J Wang, Nesrin Sabha, Frederick S Varn, Alexandra Riemenschneider, Stacey Krumholtz, Pranathi Meda Krishnamurthy, Christian A Smith, Jason Karamchandani, Jonathan K Watts, Roel G W Verhaak, Marco Gallo, James T Rutka, and Sunit Das

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    Caspase-11 drives macrophage hyperinflammation in models of Polg-related mitochondrial disease., Jordyn J VanPortfliet, Yuanjiu Lei, Muthumeena Ramanathan, Camila Guerra Martinez, Jessica Wong, Tim J Stodola, Brian Hoffmann, Kathryn Pflug, Raquel Sitcheran, Stephen C. Kneeland, Stephen A Murray, Peter J McGuire, Carolyn L Cannon, and A Phillip West

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    Celebrate the art of reproductive research with ReproBioArt!, Ewelina Bolcun-Filas

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    Celebrate the art of reproductive research with ReproBioArt!, Ewelina Bolcun-Filas

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    Cell-based high-content approach for SARS-CoV-2 neutralization identifies unique monoclonal antibodies and PI3K pathway inhibitors., Carly R Cabel, Briana A Guzman, Elaheh Alizadeh, Shuaizhi Li, Cameron Holberg, Chonlarat Wichaidit, Darren A Cusanovich, Andrew L Paek, Gregory R J Thatcher, Koenraad Van Doorslaer, Rachel S Nargi, Rachel E Sutton, Naveenchandra Suryadevara, James E Crowe, Robert H Carnahan, Samuel K Campos, and Curtis A Thorne

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    Cell-Type-Specific Changes in Intrinsic Excitability in the Subiculum following Learning and Exposure to Novel Environmental Contexts., Amy R Dunn, Sarah M Neuner, Shengyuan Ding, Kevin A Hope, Kristen M S O'Connell, and Cathleen Lutz

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    Challenges and opportunities for conceiving genetically diverse sickle cell mice., Rafiou Agoro and Gary Churchill

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    Chaotic attractor hopping yields logic operations., K Murali, Sudeshna Sinha, Vivek Kohar, Behnam Kia, and William L Ditto

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    Chapter 27 - The Mouse Developmental Anatomy Ontology (EMAPA) and the Gene Expression Database for Mouse Development (GXD), Terry F. Hayamizu and Martin Ringwald

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    Chapter 29 - The informatics of developmental phenotypes, Paul N. Schofield, Robert Hoehndorf, Georgios V. Gkoutos, and Cynthia Smith

     

    Characterization of a Mouse Model of Mitophagy-Driven Mitochondrial DNA Depletion Syndrome, Eliana R. Weinsaft

     

    Characterizing Lung Cancer Metastasis in the Novel KPDT Mouse Model, Travis Beckett

     

    Characterizing SVs associated with striatum eQTLs and addiction phenotypes in diverse mouse genomes, Aditya Gupta

     

    Characterizing the dynamics and cell state specificity of DNA methylation and demethylation at the BRCA1 promoter, Daisy Lockshire

     

    Characterizing the Molecular and Mitochondrial Changes in Neuronal Pathology of CMT2D, Jinho Kim

     

    Chromatin State Maps of Blood Pressure-Relevant Renal Segments Reveal Potential Regulatory Role for SNPs., Atrayee Ray, Chun Yang, Cary Stelloh, Monika Tutaj, Pengyuan Liu, Yong Liu, Qiongzi Qiu, Paul L Auer, Chien-Wei Lin, Michael E Widlansky, Aron M Geurts, Allen W Cowley, Mingyu Liang, Anne E Kwitek, Andrew S Greene, and Sridhar Rao

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    Chromosome 4 Duplication Associated with Strabismus Leads to Gene Expression Changes in iPSC-Derived Cortical Neurons., Mayra Martinez-Sanchez, William C Skarnes, Ashish Jain, Sampath Vemula, Liang Sun, Shira Rockowitz, and Mary C Whitman

     

    Classifying intracranial germ cell tumors using miRNA and methylation sequencing of cerebrospinal fluid, Ariella Tamariz

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    Clearance of p21 highly expressing senescent cells accelerates cutaneous wound healing., Nathan S Gasek, Pengyi Yan, Junyu Zhu, K-Raman Purushothaman, Taewan Kim, Lichao Wang, Binsheng Wang, William F Flynn, Mingda Sun, Chun Guo, Billy Huggins, Roshanak Sharafieh, Yueying Zhou, Vojtech Parizek, Tamar Tchkonia, James L Kirkland, Saranya P Wyles, and Ming Xu

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    Clonal dynamics and somatic evolution of haematopoiesis in mouse., Chiraag D Kapadia, Nicholas Williams, Kevin J Dawson, Caroline Watson, Matthew J Yousefzadeh, Duy Le, Kudzai Nyamondo, Sreeya Kodavali, Alex Cagan, Sarah Waldvogel, Xiaoyan Zhang, Josephine De La Fuente, Daniel Leongamornlert, Emily Mitchell, Marcus A Florez, Krzysztof Sosnowski, Rogelio Aguilar, Alejandra Martell, Anna Guzman, David E Harrison, Laura J Niedernhofer, Katherine Y King, Peter J Campbell, Jamie Blundell, Margaret A Goodell, and Jyoti Nangalia

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    Clonal hematopoiesis in myeloid malignancies and solid tumors., Xiurong Cai, Robert L Bowman, and Jennifer J. Trowbridge

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    Comparative genomics reveals common diversity and adaptation to harsh environments in the Arabian Peninsula indigenous chickens., Abdulwahad Assiri, Adriana Vallejo-Trujillo, Mohammed Al-Abri, Hussain Bahbahani, Faisal Almathen, Abulgasim Ahbara, Waleed Al Marzooqi, Abdulfatai Tijjani, Raman Akinyanju Lawal, and Olivier Hanotte

     

    Comparing Deleterious Mutation Load Between Classical Inbred Mice and Wild-Caught Mice, Jidapa Janpathompong

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    Comparison of Lysis and Amplification Methodologies for Optimal 16S rRNA Gene Profiling for Human and Mouse Microbiome Studies., Farzaneh Rastegari, Mark Driscoll, Jesse D Riordan, Joseph H Nadeau, Jethro Johnson, and George M. Weinstock

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    Comparison of N- and C-terminally endogenously GFP-tagged WEE-1.3 strains in, Lourds M Fernando, Kyrionna Golliday, Ruby Boateng, and Anna K Allen

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    Complete sequencing of ape genomes., DongAhn Yoo, Arang Rhie, Prajna Hebbar, Francesca Antonacci, Glennis A Logsdon, Steven J Solar, Dmitry Antipov, Brandon D Pickett, Yana Safonova, Francesco Montinaro, Yanting Luo, Joanna Malukiewicz, Jessica M Storer, Jiadong Lin, Abigail N Sequeira, Riley J Mangan, Glenn Hickey, Graciela Monfort Anez, Parithi Balachandran, Anton Bankevich, Christine R Beck, Arjun Biddanda, Matthew Borchers, Gerard G Bouffard, Emry Brannan, Shelise Y Brooks, Lucia Carbone, Laura Carrel, Agnes P Chan, Juyun Crawford, Mark Diekhans, Eric Engelbrecht, Cedric Feschotte, Giulio Formenti, Gage H Garcia, Luciana de Gennaro, David Gilbert, Richard E Green, Andrea Guarracino, Ishaan Gupta, Diana Haddad, Junmin Han, Robert S Harris, Gabrielle A Hartley, William T Harvey, Michael Hiller, Kendra Hoekzema, Marlys L Houck, Hyeonsoo Jeong, Kaivan Kamali, Manolis Kellis, Bryce Kille, Chul Lee, Youngho Lee, William Lees, Alexandra P Lewis, Qiuhui Li, Mark Loftus, Yong Hwee Eddie Loh, Hailey Loucks, Jian Ma, Yafei Mao, Juan F I Martinez, Patrick Masterson, Rajiv C McCoy, Barbara McGrath, Sean McKinney, Britta S Meyer, Karen H Miga, Saswat K Mohanty, Katherine M Munson, Karol Pal, Matt Pennell, Pavel A Pevzner, David Porubsky, Tamara Potapova, Francisca R Ringeling, Joana L Rocha, Oliver A Ryder, Samuel Sacco, Swati Saha, Takayo Sasaki, Michael C Schatz, Nicholas J Schork, Cole Shanks, Linnéa Smeds, Dongmin R Son, Cynthia Steiner, Alexander P Sweeten, Michael G Tassia, Françoise Thibaud-Nissen, Edmundo Torres-González, Mihir Trivedi, Wenjie Wei, Julie Wertz, Muyu Yang, Panpan Zhang, Shilong Zhang, Yang Zhang, Zhenmiao Zhang, Sarah A Zhao, Yixin Zhu, Erich D Jarvis, Jennifer L Gerton, Iker Rivas-González, Benedict Paten, Zachary A Szpiech, Christian D Huber, Tobias L Lenz, Miriam K Konkel, Soojin V Yi, Stefan Canzar, Corey T Watson, Peter H Sudmant, Erin Molloy, Erik Garrison, Craig B Lowe, Mario Ventura, Rachel J O'Neill, Sergey Koren, Kateryna D Makova, Adam M Phillippy, and Evan E Eichler

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    Complex genetic variation in nearly complete human genomes., Glennis A Logsdon, Peter Ebert, Peter A Audano, Mark Loftus, David Porubsky, Jana Ebler, Feyza Yilmaz, Pille Hallast, Timofey Prodanov, DongAhn Yoo, Carolyn Paisie, William T Harvey, Xuefang Zhao, Gianni V Martino, Mir Henglin, Katherine M Munson, Keon Rabbani, Chen-Shan Chin, Bida Gu, Hufsah Ashraf, Stephan Scholz, Olanrewaju Austine-Orimoloye, Parithi Balachandran, Marc Jan Bonder, Haoyu Cheng, Zechen Chong, Jonathan Crabtree, Mark Gerstein, Lisbeth A Guethlein, Patrick Hasenfeld, Glenn Hickey, Kendra Hoekzema, Sarah E Hunt, Matthew Jensen, Yunzhe Jiang, Sergey Koren, Youngjun Kwon, Chong Li, Heng Li, Jiaqi Li, Paul J Norman, Keisuke K Oshima, Benedict Paten, Adam M Phillippy, Nicholas R Pollock, Tobias Rausch, Mikko Rautiainen, Yuwei Song, Arda Söylev, Arvis Sulovari, Likhitha Surapaneni, Vasiliki Tsapalou, Weichen Zhou, Ying Zhou, Qihui Zhu, Michael C Zody, Ryan E Mills, Scott E Devine, Xinghua Shi, Michael E Talkowski, Mark J P Chaisson, Alexander T Dilthey, Miriam K Konkel, Jan O Korbel, Charles Lee, Christine R Beck, Evan E Eichler, and Tobias Marschall

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    Comprehensive Molecular Characterization of Adenocarcinoma of the Gastroesophageal Junction Between Esophageal and Gastric Adenocarcinomas, Yun-Suhk Suh, Deukchae Na, Ju-Seog Lee, Jeesoo Chae, EuiHyun Kim, Giyong Jang, Jieun Lee, Jimin Min, Chan-Young Ock, Seong-Ho Kong, Joshy George, Chengsheng Zhang, Hyuk-Joon Lee, Jong-Il Kim, Seong-Jin Kim, Woo Ho Kim, Charles Lee, and Han-Kwang Yang

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    Comprehensive reanalysis for CNVs in ES data from unsolved rare disease cases results in new diagnoses., German Demidov, Burcu Yaldiz, José Garcia-Pelaez, Elke de Boer, Nika Schuermans, Liedewei Van de Vondel, Ida Paramonov, Lennart F Johansson, Francesco Musacchia, Elisa Benetti, Gemma Bullich, Karolis Sablauskas, Sergi Beltran, Christian Gilissen, Alexander Hoischen, Stephan Ossowski, Richarda de Voer, Katja Lohmann, Carla Oliveira, Ana Topf, Lisenka E L M Vissers, Solve-RD Consortium, and Steven Laurie

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    Comprehensive single-cell aging atlas of healthy mammary tissues reveals shared epigenomic and transcriptomic signatures of aging and cancer., Brittany Lynn Angarola, Siddhartha Sharma, Neerja Katiyar, Hyeon Gu Kang, Djamel Nehar-Belaid, SungHee Park, Rachel Gott, Giray N Eryilmaz, Mark A LaBarge, Karolina Palucka, Jeffrey Chuang, Ron Korstanje, Duygu Ucar, and Olga Anczuków

     

    Computing Minimal Boolean Models of Gene Regulatory Networks., Guy Karlebach and Peter N Robinson

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    Contributions of mirror-image hair cell orientation to mouse otolith organ and zebrafish neuromast function., Kazuya Ono, Amandine Jarysta, Natasha C Hughes, Alma Jukic, Hui Ho Vanessa Chang, Michael R Deans, Ruth Anne Eatock, Kathleen E Cullen, Katie S Kindt, and Basile Tarchini

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    Control of Intracellular Molecular Networks Using Algebraic Methods., Luis Sordo Vieira, Reinhard Laubenbacher, and David Murrugarra

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    Correlation Measures in Metagenomic Data: The Blessing of Dimensionality, Alessandro Fuschi, Alessandra Merlotti, Thi Dong Binh Tran, Hoan Nguyen, and George M. Weinstock

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    CRISPR Activation Reverses Haploinsufficiency and Functional Deficits Caused by, Shahnaz Ghahremani, Aditya Kanwal, Anthony Pettinato, Feria Ladha, Nicholas Legere, Ketan Thakar, Yanfen Zhu, Harianto Tjong, Andrea Wilderman, W Tom Stump, Lina Greenberg, Michael J Greenberg, Justin Cotney, Chia-Lin Wei, and J Travis Hinson

     

    CRISPR/Cas13d Screen Identifies the Long Non-Coding RNA GAS5 as a Vulnerability in AML, Louisa Hagen

     

    Cross-Task Translation of Motor Recovery in Mouse Models of Stroke, Abigail Smith

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    CT-derived fat density as a predictor of cause-specific mortality in patients undergoing TAVI: Findings from a large registry subanalysis., Matej Pekař, Piotr Branny, Radim Špaček, Otakar Jiravský, Jan Novák, Jakub Balušík, Daniel Daniš, Jan Hečko, Marek Kantor, Bogna Jiravská Godula, Lubomír Blaha, Radek Neuwirth, and Martin Šimek

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    Cutaneous dysbiosis characterizes the post-allogeneic hematopoietic stem cell transplantation period., Adela R Cardones, Akintunde Emiola, Russell P Hall, Anthony D Sung, Jennifer Zhang, Amy J Petty, Charles Puza, Lauren M Bohannon, Amy T Bush, Meagan V Lew, Elizabeth Fleming, Yingai J Jin, Krista Rowe Nichols, Vaibhav Jain, Simon G Gregory, Keith M Sullivan, Nelson J Chao, and Julia Oh

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    Cysteinyl leukotrienes stimulate gut absorption of food allergens to promote anaphylaxis in mice., Laura R Hoyt, Elise Liu, Eli C Olson, Danielle R Jacobsen, Emily R Siniscalco, Rebecca A Krier-Burris, Kara G Greenfield, Caleb D McBride, Mia M Alfajaro, Julien A R Amat, Zhe Zhao, Lan Xu, Vivek M. Philip, Aditi Verma, Slim Fourati, Donna L Senger, Lingdi Zhang, Supinda Bunyavanich, Sarah E Glass, Robert J Coffey, Craig B Wilen, Adam Williams, and Stephanie C Eisenbarth

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    Deciphering the longitudinal trajectories of glioblastoma ecosystems by integrative single-cell genomics., Avishay Spitzer, Kevin C Johnson, Masashi Nomura, Luciano Garofano, Djamel Nehar-Belaid, Noam Galili Darnell, Alissa C Greenwald, Lillian Bussema, Young Taek Oh, Frederick S Varn, Fulvio D'Angelo, Simon Gritsch, Kevin J Anderson, Simona Migliozzi, L Nicolas Gonzalez Castro, Tamrin Chowdhury, Nicolas Robine, Catherine Reeves, Jong Bae Park, Anuja Lipsa, Frank Hertel, Anna Golebiewska, Simone P Niclou, Labeeba Nusrat, Sorcha Kellet, Sunit Das, Hyo-Eun Moon, Sun Ha Paek, Franck Bielle, Alice Laurenge, Anna Luisa Di Stefano, Bertrand Mathon, Alberto Picca, Marc Sanson, Shota Tanaka, Nobuhito Saito, David M Ashley, Stephen T Keir, Keith L Ligon, Jason T Huse, W K Alfred Yung, Anna Lasorella, Antonio Iavarone, Roel G W Verhaak, Itay Tirosh, and Mario L Suvà

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    Deciphering the Role of Kruppel-like Factor 9 in Sepsis and Immunity: Perspectives from Joint Collective Omics Data and a Literature Review, Mohamed Alfaki, Mohammed Toufiq, Kaavya S, Manikannan Mathayan, Alangudi Natarajan Palaniappan, Anbarasu Deenadayalan, Ramalingam Bethunaickan, Sabri Boughorbel, Yoann Zerbib, Darawan Rinchai, Mathieu Garand, Damien Chaussabel, and Basirudeen Syed Ahamed Kabeer

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    Defining the microbiome of the head and neck: A contemporary review, Ruwaa Samarrai, Samantha Frank, Avery Lum, Kristina Woodis, George M. Weinstock, and Daniel Roberts

     

    Defining the Role of TOP1MT in mtDNA Stability, Release, and Innate Immunity, Lena DuPont

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    De Novo Assembly of the Nearly Complete Fathead Minnow Reference Genome Reveals a Repetitive but Compact Genome, John W. Martinson, David C. Bencic, Gregory P. Toth, Mitchell S. Kostich, Robert W. Flick, Mary J. See, David Lattier, Adam D. Biales, and Weichun Huang

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    Detecting Cardiovascular Protein-Protein Interactions by Proximity Proteomics, Jared S. Kushner, Guoxia Liu, Robyn J. Eisert, Gary A. Bradshaw, Geoffrey S. Pitt, J Travis Hinson, Marian Kalocsay, and Steven O. Marx

     

    Determining function for core and strain specific genes in Staphylococcus epidermidis using CRISPRi, Cassandra Correa

     

    Determining the Effect of Mitochondrial Respiration-Targeted Drugs on Leukemia Stem Cells in a Mouse Model of Acute Myeloid Leukemia, Mia Corradi

     

    Determining the Mechanisms Responsible for Infertility in Homozygous Males of the 5XE Mutant Mouse Model, Mae D'Ambra

     

    Development of a Humanized Mouse Model of Atherosclerosis., Margot Evans

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    Differential RNA methylation using multivariate statistical methods, Deepak Nag Ayyala, Jianan Lin, and Zhengqing Ouyang

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    Disagreement on foundational principles of biological aging., Vadim N Gladyshev, Benjamin Anderson, Hanna Barlit, Benjamin Barré, Samuel Beck, Bahareh Behrouz, Daniel W Belsky, Amandine Chaix, Manish Chamoli, Brian H Chen, Kaiyang Cheng, Jane Chuprin, Gary Churchill, Andrea Cipriano, Alex Colville, Joris Deelen, Yuri Deigin, KeHuan K Edmonds, Bradley W English, Ruogu Fang, Michael Florea, Iosif M Gershteyn, Diljeet Gill, Laura H Goetz, Vera Gorbunova, Patrick T Griffin, Steve Horvath, Martin Borch Jensen, Xin Jin, Sara Jovanovska, Kathrin M Kajderowicz, Tomoko Kasahara, Csaba Kerepesi, Subhash Kulkarni, Vyacheslav M Labunskyy, Morgan E Levine, Sergiy Libert, J Yuyang Lu, Yuancheng Ryan Lu, Riccardo E Marioni, Brianah M McCoy, Wayne Mitchell, Mahdi Moqri, Farzaneh Nasirian, Peter Niimi, Hamilton Se-Hwee Oh, Brian Okundaye, Andrey A Parkhitko, Leonid Peshkin, Mia Petljak, Jesse R Poganik, Glen Pridham, Daniel E L Promislow, Weronika Prusisz, Margaux Quiniou, Ken Raj, Daniel Richard, Jose Luis Ricon, Jarod Rutledge, Morten Scheibye-Knudsen, Nicholas J Schork, Andrei Seluanov, Michael Shadpour, Anastasia V Shindyapina, Steven R Shuken, Sruthi Sivakumar, Thomas Stoeger, Ayumu Sugiura, Nadia R Sutton, Alexander Suvorov, Andrei E Tarkhov, Emma C Teeling, Alexandre Trapp, Alexander Tyshkovskiy, Maximilian Unfried, Cavin K Ward-Caviness, Sun Hee Yim, Kejun Ying, Jeffrey Yunes, Bohan Zhang, and Alex Zhavoronkov

     

    Dissecting Keratinocyte Responses to Commensal and Pathogenic Staphylococcus Species Using a 3D Human Skin Model, Reilly E. Richardson

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    Distinct immune and transcriptomic profiles in dominant versus subordinate males in mouse social hierarchies, Won Lee, Tyler M. Milewski, Madeleine F. Dwortz, Rebecca L. Young, Andrew D. Gaudet, Laura K. Fonken, Frances A. Champagne, and James P. Curley

     

    Diverging Phenotypes and Regional Accumulation of Human Microglia in Engrafted hCSF1 - and hll-34-expressing Mice, Ella Jean Raymundo

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    Domestic chicken diversity: Origin, distribution, and adaptation., Raman Akinyanju Lawal and O Hanotte

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    DTiGEMS+: drug-target interaction prediction using graph embedding, graph mining, and similarity-based techniques., Maha A Thafar, Rawan S Olayan, Haitham Ashoor, Somayah Albaradei, Vladimir B Bajic, Xin Gao, Takashi Gojobori, and Magbubah Essack

     

    Dynamic single cell transcriptomics defines kidney FGF23/KL bioactivity and novel segment-specific inflammatory targets., Rafiou Agoro, Jered Myslinski, Yamil G Marambio, Danielle Janosevic, Kayleigh N Jennings, Sheng Liu, Lainey M Hibbard, Fang Fang, Pu Ni, Megan L Noonan, Emmanuel Solis, Xiaona Chu, Yue Wang, Pierre C Dagher, Yunlong Liu, Jun Wan, Takashi Hato, and Kenneth E White

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    Effective integration of multi-omics with prior knowledge to identify biomarkers via explainable graph neural networks., Rohit K Tripathy, Zachary Frohock, Hong Wang, Gregory Cary, Stephen Keegan, Gregory W. Carter, and Yi Li

     

    Effects of CD47 Expression on Macrophage-Mediated Phagocytosis of Acute Myeloid Leukemia, Kayla Koenig

     

    Effects of Tryptophan Metabolites on Polarization of CD8+ Tfh-like T Cells, Eamon Cole

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    Elevated mitochondrial membrane potential is a therapeutic vulnerability in Dnmt3a-mutant clonal hematopoiesis., Kira Young, Mohsen Hosseini, Jayna J Mistry, Claudia Morganti, Taylor S Mills, Xiurong Cai, Brandon T James, Griffin J Nye, Natalie R Fournier, Veronique Voisin, Ali Chegini, Aaron D Schimmer, Gary D Bader, Grace Egan, Marc R Mansour, Grant A Challen, Eric M Pietras, Kelsey H Fisher-Wellman, Keisuke Ito, Steven M Chan, and Jennifer J. Trowbridge

     

    Emerging CRISPR Therapies for Precision Gene Editing and Modulation in the Cardiovascular Clinic., Nicholas J Legere and J Travis Hinson

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    Enhanced development of functional human NK cells in NOD-scid-IL2rg mice expressing human IL15, Ken-Edwin Aryee, Lisa M. Burzenski, Li-Chin Yao, James G. Keck, Dale L. Greiner, Leonard D. Shultz, and Michael A. Brehm

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    Environmental Factors Exacerbate Parkinsonian Phenotypes in an Asian-Specific Knock-In LRRK2 Risk Variant in Mice, Zoë Bichler, Sarivin Vanan, Zhiwei Zhang, Qianying (Sally) Dong, Jolene Wei Ling Lee, Chengwu Zhang, Liting Hang, Mei Jiang, Parasuraman Padmanabhan, Wuan Ting Saw, Zhidong Zhou, Balázs Gulyás, Kah Leong Lim, Li Zeng, and Eng King Tan

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    E.PathDash, pathway activation analysis of publicly available pathogen gene expression data., Lily Taub, Thomas H Hampton, Sharanya Sarkar, Georgia Doing, Samuel L Neff, Carson E Finger, Kiyoshi Ferreira Fukutani, and Bruce A Stanton

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    Ethical Frameworks for Data-Driven Environmental Health Studies in the AI Era, Miao Yu, Mingliang Fang, and Bin Wang

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    Ethical Frameworks for Data-Driven Environmental Health Studies in the AI Era., Miao Yu, Mingliang Fang, and Bin Wang

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    Evaluating the feasibility of gene replacement strategies to treat MTRFR deficiency., Samia L Pratt, Mariana Zarate-Mendez, Lidiia Koludarova, Sonja Jansson, Mikko Airavaara, Irena Hlushchuk, David Coleman, Caleb Heffner, Rita Horvath, Brendan J Battersby, and Robert W. Burgess

     

    Evaluating the impact of mutant alleles on venetoclax and cytarabine sensitivity in acute myeloid leukemia (AML) cell lines, Margaret Leonard

     

    Evaluation of cage micro-environment of mice housed on various types of bedding materials., Ellen Smith, Jason D Stockwell, Isabelle Schweitzer, Stephen H Langley, and Abigail L Smith

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    Evidence for coopetition at the maternal-fetal interface shaping placental invasion., Junaid Afzal, Yasir Suhail, Wenqiang Du, Yamin Liu, Ramalakshmi Ramasamy, Zukai Liu, Ruchi Goyal, Ashkan Novin, Sameera Suhail, Jamie Maziarz, Khadija Wali, Paul Robson, Günter P Wagner, and Kshitiz

     

    Evidence of Renal Iron and FGF23 Signaling Interdependence on Vitamin D Homeostasis in Sickle Cell Disease, Emily Winnicki

     

    Examining and optimizing the embryoid body model for early embryonic germ layer development in diverse hiPSC lineages, Nora Lippai

     

    Exploring Abnormal Neurofilament Aggregates at the Neuromuscular Junction of a Charcot-Marie- Tooth Disease Type 2E Mouse Model, Celeste Martinez

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    Exploring the composition of placental microbiome and its potential origin in preterm birth., Marwa Saadaoui, Mohamed Nadhir Djekidel, Selvasankar Murugesan, Manoj Kumar, Duaa Elhag, Parul Singh, Basirudeen Syed Ahamed Kabeer, Alexandra Katharina Marr, Tomoshige Kino, Tobias Brummaier, Rose McGready, François Nosten, Damien Chaussabel, Annalisa Terranegra, and Souhaila Al Khodor

     

    Exploring the Role of TIE2 Activation in Modulating CAA Pathology: Focus on BBB Integrity and Hemorrhagic Lesions in Aged BXW.APP/PSl Mice, Eliana Liporace

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    Extensive identification of genes involved in congenital and structural heart disorders and cardiomyopathy., Nadine Spielmann, Gregor Miller, Tudor I Oprea, Chih-Wei Hsu, Gisela Fobo, Goar Frishman, Corinna Montrone, Hamed Haseli Mashhadi, Jeremy Mason, Violeta Munoz Fuentes, Stefanie Leuchtenberger, Andreas Ruepp, Matias Wagner, Dominik S Westphal, Cordula Wolf, Agnes Görlach, Adrián Sanz-Moreno, Yi-Li Cho, Raffaele Teperino, Stefan Brandmaier, Sapna Sharma, Isabella Rikarda Galter, Manuela A Östereicher, Lilly Zapf, Philipp Mayer-Kuckuk, Jan Rozman, Lydia Teboul, Rosie K A Bunton-Stasyshyn, Heather Cater, Michelle Stewart, Skevoulla Christou, Henrik Westerberg, Amelia M Willett, Janine M Wotton, Willson B Roper, Audrey E Christiansen, Christopher S Ward, Jason D Heaney, Corey L Reynolds, Jan Prochazka, Lynette Bower, David Clary, Mohammed Selloum, Ghina Bou About, Olivia Wendling, Hugues Jacobs, Sophie Leblanc, Hamid Meziane, Tania Sorg, Enrique Audain, Arthur Gilly, Nigel W Rayner, IMPC consortium, Genomics England Research Consortium, Marc-Phillip Hitz, Eleftheria Zeggini, Eckhard Wolf, Radislav Sedlacek, Stephen A Murray, Karen L. Svenson, Robert E Braun, Jacqueline K White, Lois Kelsey, Xiang Gao, Toshihiko Shiroishi, Ying Xu, Je Kyung Seong, Fabio Mammano, Glauco P Tocchini-Valentini, Arthur L Beaudet, Terrence F Meehan, Helen Parkinson, Damian Smedley, Ann-Marie Mallon, Sara E Wells, Harald Grallert, Wolfgang Wurst, Susan Marschall, Helmut Fuchs, Steve D M Brown, Ann M Flenniken, Lauryl M J Nutter, Colin McKerlie, Yann Herault, K C Kent Lloyd, Mary E Dickinson, Valerie Gailus-Durner, and Martin Hrabe de Angelis

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    Extracellular matrix in cancer progression and therapy, Xiuxiu He, Byoungkoo Lee, and Yi Jiang

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    Extracellular peroxiredoxin 5 exacerbates atherosclerosis via the TLR4/MyD88 pathway., Hyae Yon Kweon, Eun Ju Song, Se-Jin Jeong, SoonHo Lee, Seong-Keun Sonn, Seungwoon Seo, Jing Jin, Sinai Kim, Tae Kyeong Kim, Shin Hye Moon, Doyeon Kim, Young Mi Park, Hyun Ae Woo, and Goo Taeg Oh

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    Extravillous trophoblasts reverse the decidualization induced increase in matrix production by secreting TGFβ antagonists Emilin-1 and Gremlin-1., Yasir Suhail, Yamin Liu, Junaid Afzal, Wenqiang Du, Paul Robson, Ashkan Novin, Ramalakshmi Ramasamy, and Kshitiz

     

    Ferroptosis regulates hemolysis in stored murine and human red blood cells., Angelo D'Alessandro, Gregory R Keele, Ariel Hay, Travis Nemkov, Eric J Earley, Daniel Stephenson, Matthew J Vincent, Xutao Deng, Mars Stone, Monika Dzieciatkowska, Kirk C Hansen, Steven Kleinman, Steven L Spitalnik, Nareg Roubinian, Philip J Norris, Michael P Busch, Grier P Page, Brent R Stockwell, Gary Churchill, and James C Zimring

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    Folic Acid and Methyltetrahydrofolate Supplementation in the, Karen E Christensen, Marie-Lou Faquette, Daniel Leclerc, Vafa Keser, Yan Luan, Jeanna L Bennett-Firmin, Olga V Malysheva, Alaina M Reagan, Gareth R Howell, Marie A Caudill, Teodoro Bottiglieri, and Rima Rozen

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    From gene modules to gene markers: an integrated AI-human approach selects CD38 to represent plasma cell-associated transcriptional signatures., Basirudeen Syed Ahamed Kabeer, Bishesh Subba, Darawan Rinchai, Mohammed Toufiq, Taushif Khan, Marina Yurieva, and Damien Chaussabel

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    FYN regulates aqueous humor outflow and IOP through the phosphorylation of VE-CADHERIN., Krishnakumar Kizhatil, Graham Clark, Daniel K Sunderland, Aakriti Bhandari, Logan J Horbal, Revathi Balasubramanian, and Simon W M John

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    Generating Mouse Models Using Zygote Electroporation of Nucleases (ZEN) Technology with High Efficiency and Throughput., Wenbo Wang, Yingfan Zhang, and Haoyi Wang

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    Genetically diverse mouse platform to xenograft cancer cells, Jennifer K Sargent, Mark A. Warner, Benjamin E. Low, William H. Schott, Todd Hoffert, David Coleman, Xing Yi Woo, Todd B Sheridan, Sonia Erattupuzha, Philipp P Henrich, Vivek M. Philip, Jeffrey Chuang, Michael V. Wiles, and Muneer G. Hasham

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    Genetic context modulates aging and degeneration in the murine retina., Olivia J Marola, Michael MacLean, Travis L Cossette, Cory A Diemler, Amanda A Hewes, Alaina M Reagan, Jonathan Nyandu Kanyinda, Daniel A Skelly, and Gareth R Howell

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    Genetic Deletion of Sarm1 in Mouse Models of Three Neurological Diseases., Courtney L Hatton, Markus Terrey, Maximiliano Presa, Jennifer L Ryan, Sara Perkins, Victoria E. Kennedy, Cathleen Lutz, and Robert W. Burgess

     

    Genetic mapping and characterization of nmf364a, a chemically-induced mutation leading to retinal degeneration, Fiona Picone

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    Genetic variation modulates susceptibility to aberrant DNA hypomethylation and imprint deregulation in naive pluripotent stem cells., C Parikh, R A Glenn, Y Shi, K Chatterjee, K Kasliwal, Emily Swanzey, S Singer, S C Do, Y Zhan, Y Furuta, M Tahiliani, E Apostolou, A Polyzos, R Koche, J G Mezey, T Vierbuchen, and M Stadtfeld

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    Genomic medicine year in review: 2024., Teri A Manolio, Jahnavi Narula, Alauna Rupert, Carol J Bult, Rex L Chisholm, Geoffrey S Ginsburg, Eric D Green, Gillian Hooker, Gail P Jarvik, George A Mensah, Erin M Ramos, Dan M Roden, Robb Rowley, Casey Overby Taylor, and Marc S Williams

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    Genomic reanalysis of a pan-European rare-disease resource yields new diagnoses., Steven Laurie, Wouter Steyaert, Elke de Boer, Kiran Polavarapu, Nika Schuermans, Anna K Sommer, German Demidov, Kornelia Ellwanger, Ida Paramonov, Coline Thomas, Stefan Aretz, Jonathan Baets, Elisa Benetti, Gemma Bullich, Patrick F Chinnery, Jill Clayton-Smith, Enzo Cohen, Daniel Danis, Jean-Madeleine de Sainte Agathe, Anne-Sophie Denommé-Pichon, Jordi Diaz-Manera, Stephanie Efthymiou, Laurence Faivre, Marcos Fernandez-Callejo, Mallory Freeberg, José Garcia-Pelaez, Lena Guillot-Noel, Tobias B Haack, Mike Hanna, Holger Hengel, Rita Horvath, Henry Houlden, Adam Jackson, Lennart Johansson, Mridul Johari, Erik-Jan Kamsteeg, Melanie Kellner, Tjitske Kleefstra, Didier Lacombe, Hanns Lochmüller, Estrella López-Martín, Alfons Macaya, Anna Marcé-Grau, Aleš Maver, Heba Morsy, Francesco Muntoni, Francesco Musacchia, Isabelle Nelson, Vincenzo Nigro, Catarina Olimpio, Carla Oliveira, Jaroslava Paulasová Schwabová, Martje G Pauly, Borut Peterlin, Sophia Peters, Rolph Pfundt, Giulio Piluso, Davide Piscia, Manuel Posada, Selina Reich, Alessandra Renieri, Lukas Ryba, Karolis Šablauskas, Marco Savarese, Ludger Schöls, Leon Schütz, Verena Steinke-Lange, Giovanni Stevanin, Volker Straub, Marc Sturm, Morris A Swertz, Marco Tartaglia, Iris B A W Te Paske, Rachel Thompson, Annalaura Torella, Christina Trainor, Bjarne Udd, Liedewei Van de Vondel, Bart van de Warrenburg, Jeroen van Reeuwijk, Jana Vandrovcova, Antonio Vitobello, Janet Vos, Emílie Vyhnálková, Robin Wijngaard, Carlo Wilke, Doreen William, Jishu Xu, Burcu Yaldiz, Luca Zalatnai, Birte Zurek, Solve-RD DITF-GENTURIS, Solve-RD DITF-ITHACA, Solve-RD DITF-EURO-NMD, Solve-RD DITF-RND, Solve-RD consortium, Anthony J Brookes, Teresinha Evangelista, Christian Gilissen, Holm Graessner, Nicoline Hoogerbrugge, Stephan Ossowski, Olaf Riess, Rebecca Schüle, Matthis Synofzik, Alain Verloes, Leslie Matalonga, Han G Brunner, Katja Lohmann, Richarda M de Voer, Ana Töpf, Lisenka E L M Vissers, Sergi Beltran, and Alexander Hoischen

     

    Genomic sequencing of a pregnancy associated symptomatic meningioma of the diaphragma sellae: a case report., Nathan Leclair, William A Lambert, Qian Wu, Leo Wolansky, Kevin Becker, Lei Li, Lakshmi Leishangthem, and Ketan R Bulsara

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    gom1 Mutant Mice as a Model of Otitis Media, Tihua Zheng, Wenyi Huang, Heping Yu, Bo Hua Hu, Peter Song, Christopher McCarty, Lu Lu, Joseph Jaster, Ge Jin, Yan Zhang, and Qing Yin Zheng

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    Gridded Visualization of Statistical Trees for High‐Dimensional Multipartite Data in Systems Genetics, Jane L. Adams, Robyn L Ball, Jason A. Bubier, and Elissa J Chesler

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    Gut metagenomes reveal interactions between dietary restriction, ageing and the microbiome in genetically diverse mice., Lev Litichevskiy, Maya Considine, Jasleen Gill, Vasuprada Shandar, Timothy O Cox, Hélène C Descamps, Kevin M Wright, Kevin R Amses, Lenka Dohnalová, Megan J Liou, Monika Tetlak, Mario R Galindo-Fiallos, Andrea C Wong, Patrick Lundgren, Junwon Kim, Giulia T Uhr, Ryan J Rahman, Sydney Mason, Carter Merenstein, Frederic D Bushman, Anil Raj, Fiona Harding, Zhenghao Chen, G V Prateek, Martin Mullis, Andrew Deighan, Laura Robinson, Ceylan Tanes, Kyle Bittinger, Meenakshi Chakraborty, Ami S Bhatt, Hongzhe Li, Ian Barnett, Emily R Davenport, Karl W Broman, Maayan Levy, Robert L Cohen, David Botstein, Adam Freund, Andrea Di Francesco, Gary Churchill, Mingyao Li, and Christoph A Thaiss

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    HAND1, partially mediated through ape-specific LTR binding, is essential for human extra-embryonic mesenchyme derivation from iPSCs., Zukai Liu, Yuliana Tan, William F Flynn, Lili Sun, Ponthip Pratumkaew, Juliana Alcoforado Diniz, Nélio A J Oliveira, Justin A McDonough, William C Skarnes, and Paul Robson

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    Harnessing the human gut microbiota: an emerging frontier in combatting multidrug-resistant bacteria., Wenwen Ding, Yiwen Cheng, Xia Liu, Zhangcheng Zhu, Lingbin Wu, Jie Gao, Wenhui Lei, Yating Li, Xin Zhou, Jian Wu, Yongtao Gao, Zongxin Ling, and Ruilai Jiang

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    Health Professionals' Preferences for Next-Generation Sequencing in the Diagnosis of Suspected Genetic Disorders in the Paediatric Population., Mario Cesare Nurchis, Gerardo Altamura, Gian Marco Raspolini, Enrico Capobianco, Luca Salmasi, and Gianfranco Damiani

     

    Hematopoietic stem cell gene therapy improves outcomes in a clinically relevant mouse model of multiple sulfatase deficiency., Vi Pham, Lucas Tricoli, Xinying Hong, Parith Wongkittichote, Carlo Castruccio Castracani, Amaliris Guerra, Lars Schlotawa, Laura A Adang, Amanda Kuhs, Margaret M Cassidy, Owen Kane, Emily Tsai, Maximiliano Presa, Cathleen Lutz, Stefano B Rivella, and Rebecca C Ahrens-Nicklas

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    High-Throughput Echocardiography-Guided Induction of Myocardial Ischemia/Reperfusion in Mice., Florian Sicklinger, Niklas Hartmann, Attila Kovacs, Carla Weinheimer, Jess Nigro, Tobias Thiemann, Junedh M Amrute, David Schumacher, Moritz P Kornadt, Laura M Wienecke, Lennart Rompel, Johannes Fischer, John F Bachman, Olivia Bedard, Shibali Das, Tim C Kuhn, Mirko Völkers, Ralf P Brandes, Rafael Kramann, Nadia Rosenthal, Norbert Frey, Kory J Lavine, and Florian Leuschner

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    Hippocampal-prefrontal functional neural networks in a rat model of fragile X syndrome are poorly organized with limited resiliency., Mohamed Ouardouz, Patrick Jasinski, Mohamed Khalife, J Matthew Mahoney, Amanda E Hernan, and Rod C Scott

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    Histone Modifications and Their Contributions to Hypertension., Atrayee Ray, Cary Stelloh, Yong Liu, Alison Meyer, Aron M Geurts, Allen W Cowley, Andrew S Greene, Mingyu Liang, and Sridhar Rao

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    HNRNPC and m6A RNA methylation control oncogenic transcription and metabolism in T-cell leukemia., Jonas De Kesel, Igor Fijalkowski, Tim Pieters, Cristina Borin, Kasper Thorhauge Christensen, Manou Wittouck, Jolien Van Laere, Laura Guerrero, Lindy Reunes, Marino Caruso, Bijal Thakkar, Wouter Sleeckx, Luyao Kevin Xu, Filip Van Nieuwerburgh, Dieter Deforce, Kim De Keersmaecker, Tim Lammens, Steven Goossens, Tom Taghon, Cuijuan Han, Giulia Veltri, Valentina Serafin, Bruno Palhais, Nitesh D Sharma, Hao Huang, Hudan Liu, Ksenia Matlawska-Wasowska, Ana Milovanovic, Eva Maria Novoa, Eric Wang, and Panagiotis Ntziachristos

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    Human iPSC-derived microglia sense and dampen hyperexcitability of cortical neurons carrying the epilepsy-associated, Zhefu Que, Maria I Olivero-Acosta, Morgan Robinson, Ian Chen, Jingliang Zhang, Kyle Wettschurack, Jiaxiang Wu, Tiange Xiao, C Max Otterbacher, Vinayak Shankar, Hope Harlow, Seoyong Hong, Benjamin Zirkle, Muhan Wang, Ningren Cui, Purba Mandal, Xiaoling Chen, Brody Deming, Manasi Halurkar, Yuanrui Zhao, Jean-Christophe Rochet, Ranjie Xu, Amy L Brewster, Long-Jun Wu, Chongli Yuan, William C Skarnes, and Yang Yang

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    Human Phenotype Ontology Annotations for Rare Congenital Conditions: Application to Arthrogryposis Multiplex Congenita., Shahrzad Nematollahi, Reggie C Hamdy, Harold van Bosse, Joyce Li, Daniel Blanshay-Goldberg, Johanna I P de Vries, Klaus Dieterich, Isabel Filges, Tanya Bedard, Melissa Haendel, Monica Munoz Torres, Peter N Robinson, and Noémi Dahan-Oliel

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    Hypertonic Saline Induces Host Protective Immune Responses against, Tran Xuan Ngoc Huy, Trang Thi Nguyen, Said Abdi Salad, Ched Nicole Turbela Aguilar, Alisha Wehdnesday Bernardo Reyes, Lauren Togonon Arayan, WonGi Min, Hu Jang Lee, Huynh Tan Hop, and Suk Kim

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    Identification of Distinct Immune Cell Subsets Associated With Asymptomatic Infection, Disease Severity, and Viral Persistence in COVID-19 Patients, Xiaorui Wang, Han Bai, Junpeng Ma, Hongyu Qin, Qiqi Zeng, Fang Hu, Tingting Jiang, Weikang Mao, Yang Zhao, Xiaobei Chen, Xin Qi, Mengyang Li, Jiao Xu, Jingcan Hao, Yankui Wang, Xi Ding, Yuanrui Liu, Tianlong Huang, Chao Fang, Changli Ge, Dong Li, Ke Hu, Xianwen Ren, Baojun Zhang, Binghong Zhang, Bingyin Shi, and Chengsheng Zhang

     

    Identifying Genetic Modifiers of Epilepsy Resilience and Susceptibility, Gianna Durante

     

    Identifying Markers to Determine Optimal Stage of Differentiation of Retinal Pigmented Epithelial Cells into Photoreceptors, Carlos Antonio Cisneros

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    IL-4i1 Regulation of Immune Protection During Mycobacterium tuberculosis Infection., Lerato Hlaka, Mumin Ozturk, Julius E Chia, Shelby-Sara Jones, Shandre Pillay, Sibongiseni K L Poswayo, Thabo Mpotje, Justin K Nono, Simphiwe R N Simelane, Suraj P Parihar, Sugata Roy, Harukazu Suzuki, Frank Brombacher, and Reto Guler

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    Immunosuppressive Tumor Microenvironment of Osteosarcoma., Aaron M Taylor, Jianting Sheng, Patrick Ks Ng, Jeffrey M. Harder, Parveen Kumar, Ju Young Ahn, Yuliang Cao, Alissa M Dzis, Nathaniel L. Jillette, Andrew Goodspeed, Avery Bodlak, Qian Wu, Michael S Isakoff, Joshy George, Jessica D S Grassmann, Diane Luo, William F Flynn, Elise T Courtois, Paul Robson, Masanori Hayashi, Alini Trujillo Paolillo, Antonio Sergio Petrilli, Silvia Regina Caminada de Toledo, Fabiola Sara Balarezo, Adam D Lindsay, Bang Hoang, Stephen T C Wong, and Ching C Lau

     

    Impact of Age and Sex on Bladder Function and Stum Gene Expression in C57BL/6J Mice, Maya M. Allen

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    Impact of antibody Fc engineering on translational pharmacology, and safety: insights from industry case studies., Frank R Brennan, J Ryan Polli, Jean Sathish, Melissa Ramones, Babette Wolf, Tilman Schlothauer, Shirley J Peters, Curtis C Maier, Changhua Ji, David L Wensel, Derrick Witcher, Patricia C Ryan, T Scott Manetz, Adriano Flora, Brian Soper, Birgit Fogal, Lindsey Dzielak, Xiaoting Wang, Prathap Nagaraja Shastri, Karen Price, Michael Doyle, Nidhi Sharda, Mary Struthers, Maximilian Brinkhaus, Bianca Balbino, Eric Stefanich, Masaki Honda, Jan Terje Andersen, Shermaine Mitchell-Ryan, and David P Humphreys

     

    Impact of environment on pediatric and adult brain tumors: The 2023 Brain Tumor Epidemiology Consortium meeting report., Kimberly J Johnson, Luc Bauchet, Roberta McKean-Cowdin, Carol Kruchko, Ching C Lau, Quinn T Ostrom, Michael E Scheurer, John Villano, and Yan Yuan

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    Improvement of variant reclassification in genetic neurodevelopmental conditions., Michelle Kowanda, Rebecca Sheedy Smith, Jamie Lundy, Catherine Kentros, Elisheva Kleinman, Lauren Kasparson Walsh, Gerhard Schratt, Cora M Taylor, and Wendy K Chung

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    Increased longevity of circulating human IgG in an NSG Fc gamma receptor-1 deficient humanized mouse model., Hannah R Megathlin, Lisa Burzenski, Michael A Brehm, Dale L Greiner, Sathy Balu-Iyer, and Leonard D. Shultz

     

    Increasing the efficiency of transfecting vectors encoding KZFP genes into mouse embryonic stem cells, Lenny Soto Alvarez

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    Inducing Partner Preference in Mice by Chemogenetic Stimulation of CA2 Hippocampal Subfield., Adi Cymerblit-Sabba, Adam S Smith, Sarah K Williams Avram, Michelle Stackmann, Austin C Korgan, Maria C Tickerhoof, and W Scott Young

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    Influence of multi-species data on gene-disease associations in substance use disorder using random walk with restart models., Everest U Castaneda, Sharon Moore, Jason A. Bubier, Stephen K Grady, Michael A Langston, Elissa J Chesler, and Erich J Baker

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    Inhibition of the metalloprotease ADAM19 as a novel senomorphic strategy to ameliorate gut permeability and senescence markers by modulating senescence-associated secretory phenotype (SASP)., Sudipta Bar, Tyler A U Hilsabeck, B Pattavina, José Alberto López-Domínguez, Nathan Basisty, Joanna Bons, Mark Watson, Birgit Schilling, Judith Campisi, Pankaj Kapahi, and Amit Sharma

     

    Innovative strategies for the discovery of new drugs against androgenetic alopecia., Kevin J McElwee and John P Sundberg

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    Instrumented swim test for quantifying motor impairment in rodents., Natasha C Hughes, Dale C Roberts, Basile Tarchini, and Kathleen E Cullen

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    Integrating exposomics into biomedicine., Gary W Miller and Banbury Exposomics Consortium

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    Integrative QTL analysis of gene expression and chromatin accessibility identifies multi-tissue patterns of genetic regulation., Gregory R Keele, Bryan C Quach, Jennifer W Israel, Grace A Chappell, Lauren Lewis, Alexias Safi, Jeremy M Simon, Paul Cotney, Gregory E Crawford, William Valdar, Ivan Rusyn, and Terrence S Furey

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    Interindividual Genetic Differences Drive Discordance Between Serum Calcidiol and Calcitriol Concentrations in Females., Elizabeth K Hutchins, Changran Niu, Jing Xue, Debin Wan, Carolina V Campos, Molly Warren, Megan M Knuth, Michael B Whalen, Venkata S Voruganti, Rafiou Agoro, James C Fleet, Bruce D Hammock, and Folami Ideraabdullah

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    Interruption of glucagon signaling augments islet non-alpha cell proliferation in SLC7A2- and mTOR-dependent manners., Katie C Coate, Chunhua Dai, Ajay Singh, Jade Stanley, Brittney A Covington, Amber Bradley, Favour Oladipupo, Yulong Gong, Scott Wisniewski, Katelyn Sellick, Erick Spears, Greg Poffenberger, Anna Marie R Schornack, Alexandria Bustabad, Tyler Rodgers, Nandita Dey, Leonard D. Shultz, Dale L Greiner, Hai Yan, Alvin C Powers, Wenbiao Chen, and E Danielle Dean

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    Intracranial germ cell tumors: advancement in genomic diagnostics and the need for novel therapeutics., Kee Kiat Yeo, Joanna J Gell, Girish Dhall, and Ching C Lau

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    Intrinsic-dimension analysis for guiding dimensionality reduction and data fusion in multi-omics data processing., Jessica Gliozzo, Mauricio Soto-Gomez, Valentina Guarino, Arturo Bonometti, Alberto Cabri, Emanuele Cavalleri, Justin Reese, Peter N Robinson, Marco Mesiti, Giorgio Valentini, and Elena Casiraghi

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    Introducing "Identification Probability" for Automated and Transferable Assessment of Metabolite Identification Confidence in Metabolomics and Related Studies., Thomas O Metz, Christine H Chang, Vasuk Gautam, Afia Anjum, Siyang Tian, Fei Wang, Sean M Colby, Jamie R Nunez, Madison R Blumer, Arthur S Edison, Oliver Fiehn, Dean P Jones, Shuzhao Li, Edward T Morgan, Gary J Patti, Dylan H Ross, Madelyn R Shapiro, Antony J Williams, and David S Wishart

     

    Investigating BRCA1 Promoter Methylation using Molecular and Computational Approaches, Shivam Goel

     

    Investigating Novel Mutations and Developmental Timing of Congenital Diaphragmatic Hernia, Ameleen Wong

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    In vivo models of subclonal oncogenesis and dependency in hematopoietic malignancy., Robert L Bowman, Andrew J Dunbar, Tanmay Mishra, Wenbin Xiao, Michael R Waarts, Inés Fernández Maestre, Shira E Eisman, Louise Cai, Shoron Mowla, Nisargbhai Shah, Angela Youn, Laura Bennett, Suean Fontenard, Shreeya Gounder, Anushka Gandhi, Michael Bowman, Kavi O'Connor, Zachary Zaroogian, Pablo Sánchez-Vela, Anthony R Martinez Benitez, Matthew Werewski, Young Park, Isabelle S Csete, Aishwarya Krishnan, Darren Lee, Nayla Boorady, Chad R Potts, Matthew T Jenkins, Sheng F Cai, Martin P Carroll, Sara E Meyer, Linde A Miles, P Brent Ferrell, Jennifer J. Trowbridge, and Ross L Levine

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    In vivo prime editing rescues alternating hemiplegia of childhood in mice., Alexander A Sousa, Markus Terrey, Holt A Sakai, Christine Q Simmons, Elena Arystarkhova, Natalia S Morsci, Laura C. Anderson, Jun Xie, Fabian Suri-Payer, Linda C Laux, Emmanuel Roze, Sylvie Forlani, Guangping Gao, Simon Frost, Nina Frost, Kathleen J Sweadner, Alfred L George, Cathleen Lutz, and David R Liu

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    Ischemic Conditioning Promotes Transneuronal Survival and Stroke Recovery via CD36-Mediated Efferocytosis., Hyunwoo Ju, Il-Doo Kim, Ina Pavlova, Shang Mu, Keun Woo Park, Joseph Minkler, Ahmed Madkoor, Wei Wang, Xiaoman Wang, Zhuhao Wu, Jiwon Yang, Maria Febbraio, John W Cave, and Sunghee Cho

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    IsopretGO-analysing and visualizing the functional consequences of differential splicing., Guy Karlebach, Peter Hansen, Kristin Köhler, and Peter N Robinson

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    JAX-CNV: A Whole-genome Sequencing-based Algorithm for Copy Number Detection at Clinical Grade Level, Wan-Ping Lee, Qihui Zhu, Xiaofei Yang, Silvia Liu, Eliza Cerveira, Mallory Ryan, Adam Mil-Homens, Lauren Bellfy, Kai Ye, Charles Lee, and Chengsheng Zhang

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    Lessons learned from 20 years of preclinical testing in pediatric cancers., Malcolm A Smith, Peter J Houghton, Richard B Lock, John M Maris, Richard Gorlick, Raushan T Kurmasheva, Xiao-Nan Li, Beverly A Teicher, Jeffrey Chuang, Filemon S Dela Cruz, Michael A Dyer, Andrew L Kung, Michael W Lloyd, Yael P Mossé, Timothy M Stearns, Elizabeth A Stewart, Carol J Bult, and Stephen W Erickson

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    Lessons Learned in Building Expertly Annotated Multi-Institution Datasets and Hosting the RSNA AI Challenges., Felipe C Kitamura, Luciano M Prevedello, Errol Colak, Safwan S Halabi, Matthew P Lungren, Robyn L Ball, Jayashree Kalpathy-Cramer, Charles E Kahn, Tyler Richards, Jason F Talbott, George Shih, Hui Ming Lin, Katherine P Andriole, Maryam Vazirabad, Bradley J Erickson, Adam E Flanders, and John Mongan

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    Leveraging clinical intuition to improve accuracy of phenotype-driven prioritization., Martha A Beckwith, Daniel Danis, Yasemin Bridges, Julius O B Jacobsen, Damian Smedley, and Peter N Robinson

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    LONP1 regulation of mitochondrial protein folding provides insight into beta cell failure in type 2 diabetes., Jin Li, Yamei Deng, Marie Gasser, Jie Zhu, Emily M Walker, Vaibhav Sidarala, Emma C Reck, Dre L Hubers, Mabelle B Pasmooij, Chun-Shik Shin, Khushdeep Bandesh, Efthymios Motakis, Siddhi Nargund, Romy Kursawe, Venkatesha Basrur, Alexey I Nesvizhskii, Michael L. Stitzel, David C Chan, Guy A Rutter, and Scott A Soleimanpour

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    Low Dietary Folate Increases Developmental Delays in the Litters of, Karen E Christensen, Marie-Lou Faquette, Vafa Keser, Alaina M Reagan, Aaron T Gebert, Teodoro Bottiglieri, Gareth R Howell, and Rima Rozen

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    Lung fibroblasts facilitate pre-metastatic niche formation by remodeling the local immune microenvironment, Zheng Gong, Qing Li, Jiayuan Shi, Jian Wei, Peishan Li, Chih-Hao Chang, Leonard D. Shultz, and Guangwen Ren

     

    M2-lon Channel Specific Chimeric Antibodies as a Universal and Escape Mutant-Resistant Therapeutic for Influenza A, Katya Crawford

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    Machine Learning to Detect Cervical Spine Fractures Missed by Radiologists on CT: Analysis Using Seven Award-Winning Models from the RSNA 2022 Cervical Spine Fracture AI Challenge., Yingming Amy Chen, Zixuan Hu, Kevin Daniel Shek, Jefferson Wilson, Fahad Saud S Alotaibi, Christopher D Witiw, Hui Ming Lin, Robyn L Ball, Markand Patel, Shobhit Mathur, Ervin Sejdić, and Errol Colak

     

    Machine vision-based frailty assessment for genetically diverse mice., Gautam S Sabnis, Gary Churchill, and Vivek Kumar

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    Machine vision-based frailty assessment for genetically diverse mice., Gautam S Sabnis, Gary Churchill, and Vivek Kumar

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    Male caregiving experience alters hippocampal neuroplasticity and transcription independent of reproduction in a biparental species., Maria E Colt, Priyanka Agarwal, Erica R Glasper, and Heidi Fisher

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    Mapping extrachromosomal DNA amplifications during cancer progression., Hoon Kim, Soyeon Kim, Taylor E Wade, Eunchae Yeo, Anuja Lipsa, Anna Golebiewska, Kevin C Johnson, Sepil An, Junyong Ko, Yoonjoo Nam, Hwa Yeon Lee, Seunghyun Kang, Heesuk Chung, Simone P Niclou, Hyo-Eun Moon, Sun Ha Paek, Vineet Bafna, Jens Luebeck, and Roel G W Verhaak

     

    Mapping genetic effects of diverse mESC lines on cellular phenotypes with Census-seq, Madeline Rea

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    Mapping restricted introgression across the genomes of admixed indigenous African cattle breeds., Juliane Friedrich, Richard I Bailey, Andrea Talenti, Umer Chaudhry, Qasim Ali, Emmanuel F Obishakin, Chukwunonso Ezeasor, Jessica Powell, Olivier Hanotte, Abdulfatai Tijjani, Karen Marshall, James Prendergast, and Pamela Wiener

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    Mapping the genetic landscape establishing a tumor immune microenvironment favorable for anti-PD-1 response., Daniel A Skelly, John P Graham, Mingshan Cheng, Mayuko Furuta, Andrew Walter, Thomas A Stoklasek, Hongyuan Yang, Timothy M Stearns, Olivier Poirion, Ji-Gang Zhang, Jessica D S Grassmann, Diane Luo, William F Flynn, Elise T Courtois, Chih-Hao Chang, David V. Serreze, Francesca Menghi, Laura G Reinholdt, and Edison Liu

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    Marmosets as model systems for the study of Alzheimer's disease and related dementias: Substantiation of physiological tau 3R and 4R isoform expression and phosphorylation., Hasi Huhe, Sarah M Shapley, Duc M Duong, Fang Wu, Seung-Kwon Ha, Sang-Ho Choi, Julia Kofler, Yongshan Mou, Thais Rafael Guimaraes, Amantha Thathiah, Caroline M Watson, Lauren K H Schaeffer, Gregory W. Carter, Nicholas T Seyfried, Afonso C Silva, and Stacey J Sukoff Rizzo

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    Mechanisms of tandem duplication in the cancer genome., Ralph Scully, Dominik Glodzik, Francesca Menghi, Edison Liu, and Cheng-Zhong Zhang

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    Melanocortin 4 Receptor-Dependent Mechanism of ACTH in Preventing Anxiety-Like Behaviors and Normalizing Astrocyte Proteins after Early Life Seizures., Mohamed R Khalife, Colin Villarin, Juan Manuel Ruiz, Sam A McClelland, Khalil Abed Rabbo, J Matthew Mahoney, Rod C Scott, and Amanda E Hernan

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    Merritt-Putnam Symposium | Developmental and Epileptic Encephalopathies-Current Concepts and Novel Approaches., Rodney C Scott, Jenny Hsieh, Amy McTague, J Matthew Mahoney, and Catherine A Christian-Hinman

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    Meta-analysis of fecal metagenomes reveals global microbial signatures that are specific for colorectal cancer., Jakob Wirbel, Paul Theodor Pyl, Ece Kartal, Konrad Zych, Alireza Kashani, Alessio Milanese, Jonas S Fleck, Anita Y Voigt, Albert Palleja, Ruby Ponnudurai, Shinichi Sunagawa, Luis Pedro Coelho, Petra Schrotz-King, Emily Vogtmann, Nina Habermann, Emma Niméus, Andrew M Thomas, Paolo Manghi, Sara Gandini, Davide Serrano, Sayaka Mizutani, Hirotsugu Shiroma, Satoshi Shiba, Tatsuhiro Shibata, Shinichi Yachida, Takuji Yamada, Levi Waldron, Alessio Naccarati, Nicola Segata, Rashmi Sinha, Cornelia M Ulrich, Hermann Brenner, Manimozhiyan Arumugam, Peer Bork, and Georg Zeller

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    Metformin reduces the competitive advantage of Dnmt3a, Mohsen Hosseini, Veronique Voisin, Ali Chegini, Angelica Varesi, Severine Cathelin, Dhanoop Manikoth Ayyathan, Alex C H Liu, Yitong Yang, Vivian Wang, Abdula Maher, Eric Grignano, Julie A Reisz, Angelo D'Alessandro, Kira Young, Yiyan Wu, Martina Fiumara, Samuele Ferrari, Luigi Naldini, Federico Gaiti, Shraddha Pai, Grace Egan, Aaron D Schimmer, Gary D Bader, John E Dick, Stephanie Z Xie, Jennifer J. Trowbridge, and Steven M Chan

     

    Microglia differentiation from human induced pluripotent stem cells, Grace Hodgkin

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    MIDRC mRALE Mastermind Grand Challenge: AI to predict COVID severity on chest radiographs., Samuel G Armato, Karen Drukker, Lubomir Hadjiiski, Carol C Wu, Jayashree Kalpathy-Cramer, George Shih, Maryellen L Giger, Natalie Baughan, Benjamin Bearce, Adam E Flanders, Robyn L Ball, Kyle J Myers, Heather M Whitney, and The Midrc Grand Challenge Working Group

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    Mis-splicing-derived neoantigens and cognate TCRs in splicing factor mutant leukemias., Won Jun Kim, Edie I Crosse, Emma De Neef, Inaki Etxeberria, Erich Y Sabio, Eric Wang, Jan Philipp Bewersdorf, Kuan-Ting Lin, Sydney X Lu, Andrea Belleville, Nina Fox, Cynthia Castro, Pu Zhang, Takeshi Fujino, Jennifer Lewis, Jahan Rahman, Beatrice Zhang, Jacob H Winick, Alexander M Lewis, Robert F Stanley, Susan DeWolf, Brigita Meškauskaitė Urben, Meril Takizawa, Tobias Krause, Henrik Molina, Ronan Chaligne, Priya Koppikar, Jeffrey Molldrem, Mathieu Gigoux, Taha Merghoub, Anthony Daniyan, Smita S Chandran, Benjamin D Greenbaum, Christopher A Klebanoff, Robert K Bradley, and Omar Abdel-Wahab

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    Mitochondrial complex I deficiency induces Alzheimer's disease-like signatures that are reversible by targeted therapy., Huanyao Gao, Kate Jensen, Jarred Nesbitt, Mark Ostroot, Gregory Cary, Jesse Wiley, Sergey Trushin, Jens O Watzlawik, Wolfdieter Springer, Alexander Galkin, Priyanka Baloni, Cory Funk, and Eugenia Trushina

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    ML-UrineQuant: A machine learning program for identifying and quantifying mouse urine on absorbent paper., Warren G Hill, Bryce MacIver, Gary Churchill, Mariana G DeOliveira, Mark L Zeidel, and Marcelo Cicconet

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    Modifications in media composition and antioxidant support influences in vitro produced bovine blastocyst inner cell mass and trophectoderm numbers., Jessica A Keane, Lydia K Wooldridge, Mary A Oliver, Savannah L Speckhart, Kayla J Alward, Jada L Nix, Fernando H Biase, and Alan D Ealy

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    Molecular landscape of respiratory infection: A large-scale, multi-centre blood transcriptome dataset., Tracy Chew, Tiana M Pelaia, Amy L Phu, Sally Teoh, Ya Wang, Nandan Deshpande, Karan Kim, Velma Herwanto, Gunawan, Thomas Karvunidis, Yoann Zerbib, Kirsty R Short, Stephen Macdonald, Irani Thevarajan, Darawan Rinchai, Win Sen Kuan, Ben Knippenberg, Jonathan Iredell, Philip N Britton, Owen Hutchings, Warwick J Britton, John-Sebastian Eden, Sam Orde, Benjamin Tang, Anthony McLean, Damien Chaussabel, Klaus Schughart, and Maryam Shojaei

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    Monoallelic TTN Truncation Variants Identified in Individuals With DCM May Cause a Mild Skeletal Myopathy., J Travis Hinson and Ray E Hershberger

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    MorPhiC Consortium: towards functional characterization of all human genes., Mazhar Adli, Laralynne Przybyla, Tony Burdett, Paul W Burridge, Pilar Cacheiro, Howard Y Chang, Jesse M Engreitz, Luke A Gilbert, William J Greenleaf, Li Hsu, Danwei Huangfu, Ling-Hong Hung, Anshul Kundaje, Sheng Li, Helen Parkinson, Xiaojie Qiu, Paul Robson, Stephan C Schürer, Ali Shojaie, William C Skarnes, Damian Smedley, Lorenz Studer, Wei Sun, Dušica Vidović, Thomas Vierbuchen, Brian S White, Ka Yee Yeung, Feng Yue, Ting Zhou, and The MorPhiC Consortium

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    Mouse models of NADK2 deficiency analyzed for metabolic and gene expression changes to elucidate pathophysiology, G C. Murray, P Bais, C L. Hatton, Abby Tadenev, Brian Hoffmann, Tim J Stodola, K H. Morelli, Samia L Pratt, David G. Schroeder, Rosalinda A. Doty, O Fiehn, Simon W M John, Carol J Bult, Gregory A. Cox, and Robert W. Burgess

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    Multidisciplinary stakeholder-informed identification of key characteristics for implementation of workplace genetic testing., Elizabeth Charnysh, Kunal Sanghavi, Kerry A Ryan, Alyx Vogle, Alexandra Truhlar, Subhamoy Pal, Jonathan M Reader, J Scott Roberts, Charles Lee, Anya E R Prince, W Gregory Feero, and INSIGHT @ Work Consortium

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    Multiomic analysis reveals cell-type-specific molecular determinants of COVID-19 severity, Sai Zhang, Johnathan Cooper-Knock, Annika K. Weimer, Minyi Shi, Lina Kozhaya, Derya Unutmaz, Calum Harvey, Thomas H. Julian, Simone Furini, Elisa Frullanti, Francesca Fava, Alessandra Renieri, Peng Gao, Xiaotao Shen, Ilia Sarah Timpanaro, Kevin P. Kenna, J Kenneth Baillie, Mark M. Davis, Philip S. Tsao, and Michael P. Snyder

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    Multi-omic human pancreatic islet endoplasmic reticulum and cytokine stress response mapping provides type 2 diabetes genetic insights., Eishani K Sokolowski, Romy Kursawe, Vijay Selvam, Redwan M Bhuiyan, Asa Thibodeau, Chi Zhao, Cassandra N Spracklen, Duygu Ucar, and Michael L. Stitzel

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    Multiomic Network Analysis Identifies Dysregulated Neurobiological Pathways in Opioid Addiction., Kyle A Sullivan, David Kainer, Matthew Lane, Mikaela Cashman, J Izaak Miller, Michael R Garvin, Alice Townsend, Bryan C Quach, Caryn Willis, Peter Kruse, Nathan C Gaddis, Ravi Mathur, Olivia Corradin, Brion S Maher, Peter C Scacheri, Sandra Sanchez-Roige, Abraham A Palmer, Vanessa Troiani, Elissa J Chesler, Rachel L Kember, Henry R Kranzler, Amy C Justice, Ke Xu, Bradley E Aouizerat, Dana B Hancock, Eric O Johnson, Daniel A Jacobson, and V. A. Million Veteran Program.

     

    Multi-Omics Analyses to Detect Changes in the Mouse Hippocampus with Differences in Age, Diet and Strain, Grant Moen

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    Muscle-derived myostatin is a major endocrine driver of follicle-stimulating hormone synthesis., Luisina Ongaro, Xiang Zhou, Ying Wang, Hailey Schultz, Ziyue Zhou, Evan R S Buddle, Emilie Brûlé, Yeu-Farn Lin, Gauthier Schang, Adam Hagg, Roselyne Castonguay, Yewei Liu, Gloria H Su, Nabil G Seidah, Kevin C Ray, Seth J Karp, Ulrich Boehm, Frederique Ruf-Zamojski, Stuart C Sealfon, Kelly L Walton, Se-Jin Lee, and Daniel J Bernard

     

    Mutational Load in Inbred-Outbred Wild Derived Mouse Trios, Sam G. Bigalke

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    Mutation in Prkra results in cerebellar abnormality and reduced eIF2α phosphorylation in a model of DYT-PRKRA., Samuel B Burnett, Allison M Culver, Tricia A Simon, Taylor Rowson, Kenneth Frederick, Kristina Palmer, Stephen A Murray, Shannon W Davis, and Rekha C Patel

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    mzrtsim: Raw Data Simulation for Reproducible Gas/Liquid Chromatography-Mass Spectrometry-Based Nontargeted Metabolomics Data Analysis., Miao Yu and Vivek M. Philip

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    Nanomedicine targeting PPAR in adipose tissue macrophages improves lipid metabolism and obesity-induced metabolic dysfunction., Catherine C Applegate, Yifei Kang, Hongping Deng, Donglai Chen, Natalia Y Gonzalez Medina, Yuxiao Cui, Yujun Feng, Chia-Wei Kuo, Sayyed Hamed Shahoei, Hannah Kim, Hashni Epa Vidana Gamage, Matthew A Wallig, Erik R Nelson, Kelly S Swanson, and Andrew M Smith

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    NCAM1 and GDF15 are biomarkers of Charcot-Marie-Tooth disease in patients and mice, Matthew J. Jennings, Alexia Kagiava, Leen Vendredy, Emily L Spaulding, Marina Stavrou, Denisa Hathazi, Anika Grüneboom, Vicky De Winter, Burkhard Gess, Ulrike Schara, Oksana Pogoryelova, Hanns Lochmüller, Christoph H. Borchers, Andreas Roos, Robert W. Burgess, Vincent Timmerman, Kleopas A. Kleopa, and Rita Horvath

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    Necrosis drives susceptibility to Mycobacterium tuberculosis in Polg(D257A) mutator mice, C J Mabry, C G Weindel, L W Stranahan, Jordyn J VanPortfliet, J R Davis, E L Martinez, A Phillip West, K L Patrick, and R O Watson

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    Neural network analysis as a novel skin outcome in a trial of belumosudil in patients with systemic sclerosis., Ilayda Gunes, Elana J Bernstein, Shawn E Cowper, Gauri Panse, Niki Pradhan, Lucy Duran Camacho, Nicolas Page, Elizabeth Bundschuh, Alyssa Williams, Mary Carns, Kathleen Aren, Sarah Fantus, Elizabeth R Volkmann, Heather Bukiri, Chase Correia, Vijaya B Kolachalama, F Perry Wilson, Seamus Mawe, J Matthew Mahoney, and Monique Hinchcliff

     

    New Insights into Cellular Senescence and Oxygen Effects on Trophoblast Differentiation, Kelley Delgadillo Garcia

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    NIH SenNet Consortium to map senescent cells throughout the human lifespan to understand physiological health., SenNet Consortium, Paul Robson, Elise T Courtois, Jeffrey Chuang, Monica Davé, Sergii Domanskyi, Giray Naim Eryilmaz, Jon Gelfond, Shane Sanders, Asa Thibodeau, Duygu Ucar, and Brian S White

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    Non-homologous sequence interactions during meiosis: meiotic challenges and evolutionary opportunities., Beth L Dumont and Mary Ann Handel

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    Non-invasive glucose measurements in mice using mid-infrared emission spectroscopy, Marcel Mueller, Michael Grunze, Edward H. Leiter, Peter C. Reifsnyder, Ulrike Klueh, and Don Kreutzer

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    Non-neutralizing antibodies to influenza A matrix-protein-2-ectodomain are broadly effective therapeutics and resistant to viral escape mutations., Teha Kim, Lynn Bimler, Sydney L Ronzulli, Amber Y Song, Scott K Johnson, Cheryl A Jones, S Mark Tompkins, and Silke Paust

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    Normal breast tissue DNA methylation differences at regulatory elements are associated with the cancer risk factor age., Kevin C Johnson, E Andres Houseman, Jessica E King, and Brock C Christensen

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    Not a hair out of place: Polarizing and orienting sensory hair cells., Katie S Kindt and Basile Tarchini

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    Novel Flavonoid Derivatives Show Potent Efficacy in Human Lymphoma Models., Eugenio Gaudio, Paulina Biniecka, Alberto J Arribas, Eleonora Cannas, Guido J R Zaman, Derya Unutmaz, Francesco Bertoni, and Dan F Stoicescu

     

    Novel genomic therapeutic for desmoplastic small round cell tumor based on RNA sensor targeting of EWSR1::WT1 gene fusion, Ethan Giannotta

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    Obesity: Policy and Practice Recommendations for High-Risk Populations Influenced by the COVID-19 Pandemic, Kathryn N. Robinson and Deborah A. Saber

     

    Ontology-based modeling, integration, and analysis of heterogeneous clinical, pathological, and molecular kidney data for precision medicine., Yongqun Oliver He, Laura Barisoni, Avi Z Rosenberg, Peter N Robinson, Alexander D Diehl, Yichao Chen, Jim Phuong, Jens Hansen, Bruce W Herr Ii, Katy Börner, Jennifer Schaub, Nikki Bonevich, Ghida Arnous, Saketh Boddapati, Jie Zheng, Fadhl Alakwaa, Pinaki Sardar, William D Duncan, Chen Liang, M Todd Valerius, Sanjay Jain, Ravi Iyengar, Jonathan Himmelfarb, Matthias Kretzler, and Kidney Precision Medicine Project.

     

    Oxygen Sensing in Osteocytes: From Physiology to Age-related Osteoporosis., Kathryn Janeczko and Rafiou Agoro

     

    Pathophysiology and Etiology of a Novel Mouse Model for Vasculitis, Kendrick Key

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    Patient-Specific In Vivo Gene Editing to Treat a Rare Genetic Disease., Kiran Musunuru, Sarah A Grandinette, Xiao Wang, Taylor R Hudson, Kevin Briseno, Anne Marie Berry, Julia L Hacker, Alvin Hsu, Rachel A Silverstein, Logan T Hille, Aysel N Ogul, Nancy A Robinson-Garvin, Juliana C Small, Sarah McCague, Samantha M Burke, Christina M Wright, Sarah Bick, Venkata Indurthi, Shweta Sharma, Michael Jepperson, Christopher A Vakulskas, Michael Collingwood, Katie Keogh, Ashley Jacobi, Morgan Sturgeon, Christian Brommel, Ellen Schmaljohn, Gavin Kurgan, Thomas Osborne, He Zhang, Kyle Kinney, Garrett Rettig, Christopher J Barbosa, Sean C Semple, Ying K Tam, Cathleen Lutz, Lindsey A George, Benjamin P Kleinstiver, David R Liu, Kim Ng, Sadik H Kassim, Petros Giannikopoulos, Mohamad-Gabriel Alameh, Fyodor D Urnov, and Rebecca C Ahrens-Nicklas

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    Patterns of Associations with Epidemiologic Factors by High-Grade Serous Ovarian Cancer Gene Expression Subtypes., Lindsay J Collin, Kara L Cushing-Haugen, Kathryn L Terry, Ellen L Goode, Anna H Wu, Holly R Harris, Naoko Sasamoto, Daniel W Cramer, Francesmary Modugno, Esther Elishaev, Zhuxuan Fu, Kirsten B Moysich, Peter A Fasching, Celeste Leigh Pearce, Usha Menon, Aleksandra Gentry-Maharaj, Simon A Gayther, Nicolas Wentzensen, Marc T Goodman, Joshy George, Aline Talhouk, Michael S Anglesio, Susan J Ramus, David D L Bowtell, Shelley S Tworoger, Joellen M Schildkraut, Penelope M Webb, and Jennifer A Doherty

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    PDPN marks a subset of aggressive and radiation-resistant glioblastoma cells, Aram S. Modrek, Eskil Eskilsson, Ravesanker Ezhilarasan, Qianghu Wang, Lindsey D. Goodman, Yingwen Ding, Ze-Yan Zhang, Krishna P. Bhat, Thanh-Thuy T. Le, Floris P Barthel, Ming Tang, Jie Yang, Lihong Long, Joy Gumin, Frederick F. Lang, Roel G W Verhaak, Kenneth D. Aldape, and Erik P. Sulman

     

    Perceived understanding and psychosocial outcomes: employees' responses to learning results of workplace genetic testing., Elizabeth Charnysh, Sarah McCain, Alexandra Truhlar, Subhamoy Pal, Jonathan M Reader, Kunal Sanghavi, Wendy R Uhlmann, Katherine Hendy, Amy Leader, Drew Blasco, Anya E R Prince, William Gregory Feero, Rachael Brandt, Veda N Giri, Charles Lee, and J Scott Roberts

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    Performance of Algorithms Submitted in the 2023 RSNA Screening Mammography Breast Cancer Detection AI Challenge., Yan Chen, George J W Partridge, Maryam Vazirabad, Robyn L Ball, Hari M Trivedi, Felipe Campos Kitamura, Helen M L Frazer, Tara A Retson, Luyan Yao, Iain T Darker, Tatiana Kelil, John Mongan, Ritse M Mann, and Linda Moy

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    Performance of the Winning Algorithms of the RSNA 2022 Cervical Spine Fracture Detection Challenge., Ghee Rye Lee, Adam E Flanders, Tyler Richards, Felipe Kitamura, Errol Colak, Hui Ming Lin, Robyn L Ball, Jason Talbott, and Luciano M Prevedello

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    Pharmacokinetic, pharmacodynamic, and transcriptomic analysis of chronic levetiracetam treatment in 5XFAD mice: A MODEL-AD preclinical testing core study, Kristen D. Onos, Sara K. Quinney, David R. Jones, Andrea R. Masters, Ravi S Pandey, Kelly J Keezer, Carla Biesdorf, Ingrid F. Metzger, Jill A. Meyers, Johnathon Peters, Scott C. Persohn, Brian P. McCarthy, Amanda A. Bedwell, Lucas L. Figueiredo, Zackary A. Cope, Michael Sasner, Gareth R Howell, Harriet M. Jackson, Adrian L. Oblak, Bruce T. Lamb, Gregory W. Carter, Stacey J. Rizzo, and Paul R. Territo

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    Phenotypic Expansion of Knobloch Syndrome Type 2 in an Individual With a De Novo PAK2 Variant., Elizabeth A Werren, Louisa Kalsner, Jessica M Ewald, Michael Peracchio, Cameron King, Purva Vats, Peter A Audano, Peter N Robinson, Mark D Adams, Melissa A Kelly, and Adam P Matson

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    Phosphorus-independent role of FGF23 in erythropoiesis and iron homeostasis., Min Young Park, Rafiou Agoro, Stanislovas S Jankauskas, Carole Le Henaff, and Despina Sitara

     

    Phylogenetic Analysis of Recombination Rate Evolution in Mus musculus, Micah Pietraho

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    Physiological role and mechanisms of action for a long noncoding haplotype region., Hong Xue, Manoj K Mishra, Yong Liu, Pengyuan Liu, Michael Grzybowski, Rajan Pandey, Kristie Usa, Mark A Vanden Avond, Niharika Bala, Abdel A Alli, Allen W Cowley, Qiongzi Qiu, Andrew S Greene, Sridhar Rao, Caitlin C O'Meara, Aron M Geurts, and Mingyu Liang

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    Placental and Cord Blood DNA Methylation Changes Associated With Gestational Diabetes Mellitus in a Marginalized Population: The Untold Role of Saturated Fats., Fatima Ahmad, Sidra Aftab Uzair, Arun P Lakshmanan, Shaikha Alabduljabbar, Salma H Ahmed, Basirudeen Syed Ahamed Kabeer, Alexandra Katharina Marr, Tomoshige Kino, Tobias Brummaier, Rose McGready, François Nosten, Damien Chaussabel, Souhaila Al Khodor, and Annalisa Terranegra

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    Placental and Cord Blood DNA Methylation Changes Associated With Gestational Diabetes Mellitus in a Marginalized Population: The Untold Role of Saturated Fats., Fatima Ahmad, Sidra Aftab Uzair, Arun P Lakshmanan, Shaikha Alabduljabbar, Salma H Ahmed, Basirudeen Syed Ahamed Kabeer, Alexandra Katharina Marr, Tomoshige Kino, Tobias Brummaier, Rose McGready, François Nosten, Damien Chaussabel, Souhaila Al Khodor, and Annalisa Terranegra

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    Plot twist: TET2 clones save the brain., Maria Telpoukhovskaia and Jennifer J. Trowbridge

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    Pluripotent cell states and fates in human embryo models., Berna Sozen, Patrick P L Tam, and Martin Pera

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    Podoplanin-positive cell-derived small extracellular vesicles contribute to cardiac amyloidosis after myocardial infarction., Maria Cimini, Ulrich H E Hansmann, Carolina Gonzalez, Andrew D Chesney, May M Truongcao, Erhe Gao, Tao Wang, Rajika Roy, Elvira Forte, Vandana Mallaredy, Charan Thej, Ajit Magadum, Darukeshwara Joladarashi, Cindy Benedict, Water J Koch, Çağla Tükel, and Raj Kishore

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    Points to consider to avoid unfair discrimination and the misuse of genetic information: A statement of the American College of Medical Genetics and Genomics (ACMG), Laurie H. Seaver; George Khushf; Nancy M. King; Dena R. Matalon; Kunal Sanghavi; Matteo Vatta; Kristi Wees; and on behalf of the ACMG Social, Ethical and Legal Issues Committee

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    Polyploid superficial uroepithelial bladder barrier cells express features of cellular senescence across the lifespan and are insensitive to senolytics., Iman M Al-Naggar, Maria Antony, Dylan Baker, Lichao Wang, Lucas Da Cunha Godoy, Chia-Ling Kuo, Matthew O Fraser, Phillip P Smith, Ming Xu, and George A Kuchel

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    Positive allosteric modulation of the cannabinoid type-1 receptor (CB1R) in periaqueductal gray (PAG) antagonizes anti-nociceptive and cellular effects of a mu-opioid receptor agonist in morphine-withdrawn rats., Udita Datta, Leslie K Kelley, Jason W Middleton, and Nicholas W Gilpin

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    Preclinical use of a clinically-relevant scAAV9/SUMF1 vector for the treatment of multiple sulfatase deficiency., Maximiliano Presa, Rachel M Bailey, Somdatta Ray, Lauren Bailey, Saurabh Tata, Tara Murphy, Pierre-Alexandre Piec, Harold Combs, Steven J Gray, and Cathleen Lutz

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    Predicting the impact of rare variants on RNA splicing in CAGI6., Jenny Lord, Carolina Jaramillo Oquendo, Htoo A Wai, Andrew G L Douglas, David J Bunyan, Yaqiong Wang, Zhiqiang Hu, Zishuo Zeng, Daniel Danis, Panagiotis Katsonis, Amanda Williams, Olivier Lichtarge, Yuchen Chang, Richard D Bagnall, Stephen M Mount, Brynja Matthiasardottir, Chiaofeng Lin, Thomas van Overeem Hansen, Raphael Leman, Alexandra Martins, Claude Houdayer, Sophie Krieger, Constantina Bakolitsa, Yisu Peng, Akash Kamandula, Predrag Radivojac, and Diana Baralle

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    Prediction of Patient Drug Response via 3D Bioprinted Gastric Cancer Model Utilized Patient-Derived Tissue Laden Tissue-Specific Bioink., Yoo-Mi Choi, Deukchae Na, Goeun Yoon, Jisoo Kim, Seoyeon Min, Hee-Gyeong Yi, Soo-Jeong Cho, Jae Hee Cho, Charles Lee, and Jinah Jang

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    Proceedings from the Albert Charitable Trust Inaugural Workshop on 'Understanding the Acute Effects of Exercise on the Brain', Jill N. Barnes, Jeffrey M. Burns, Marcas M. Bamman, Sandra A. Billinger, Sue C. Bodine, Frank W. Booth, Patrice Brassard, Tameka A. Clemons, Paul J. Fadel, Paige C. Geiger, Swathi Gujral, Jacob M. Haus, Scott E. Kanoski, Benjamin F. Miller, Jill K. Morris, Kristen M S O'Connell, David C. Poole, Darleen A. Sandoval, J Carson Smith, Russell H. Swerdlow, Shawn N. Whitehead, Eric D. Vidoni, and Henriette van Praag

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    Pushing the boundaries of rare disease diagnostics with the help of the first Undiagnosed Hackathon., Angelica Maria Delgado-Vega, Helene Cederroth, Fulya Taylan, Katja Ekholm, Marlene Ek, Håkan Thonberg, Anders Jemt, Daniel Nilsson, Jesper Eisfeldt, Kristine Bilgrav Saether, Ida Höijer, Ozlem Akgun-Dogan, Yui Asano, Tahsin Stefan Barakat, Dominyka Batkovskyte, Gareth Baynam, Olaf Bodamer, Wanna Chetruengchai, Pádraic Corcoran, Madeline Couse, Daniel Danis, German Demidov, Eisuke Dohi, Mattias Erhardsson, Luis Fernandez-Luna, Toyofumi Fujiwara, Neha Garg, Roberto Giugliani, Claudia Gonzaga-Jauregui, Giedre Grigelioniene, Tudor Groza, Cecilia Gunnarsson, Anna Hammarsjö, Charles Kumi Hammond, Özden Hatirnaz Ng, Sirisha Hesketh, Dineshani Hettiarachchi, Maria Johansson Soller, Umn Ahmed Kirmani, Martin Kjellberg, Malin Kvarnung, Oleg Kvlividze, Kristina Lagerstedt-Robinson, Paul Lasko, Timo Lassmann, Lynette Y S Lau, Steven Laurie, Weng Khong Lim, Zhandong Liu, Mariya Lysenkova Wiklander, Prince Makay, Alassane Baneye Maiga, Carolina Maya-González, M Stephen Meyn, Ramprasad Neethiraj, Vincenzo Nigro, Felix Nordgren, Jessica Nordlund, Sara Orrsjö, Jesper Ottosson, Ugur Ozbek, Özkan Özdemir, Clyde Partin, David A Pearce, Raquel Peck, Annie Pedersen, Maria Pettersson, Monnat Pongpanich, Manuel Posada de la Paz, Arun Ramani, Juan Andres Romero, Vanessa I Romero, Richard Rosenquist, Aung Min Saw, Matthew Spencer, Eva-Lena Stattin, Chalurmpon Srichomthong, Isabel Tapia-Paez, Domenica Taruscio, Julie P Taylor, Tinatin Tkemaladze, Ian Tully, Zeynep Tümer, Wendy A G van Zelst-Stams, Alain Verloes, Emma Västerviga, Sailan Wang, Rachel Yang, Shinya Yamamoto, Vicente A Yépez, Qing Zhang, Vorasuk Shotelersuk, Samuel Agyei Wiafe, Yasemin Alanay, Lorenzo D Botto, Salman Kirmani, Aimé Lumaka, Elizabeth Emma Palmer, Ratna Dua Puri, Valtteri Wirta, Anna Lindstrand, Orion J Buske, Mikk Cederroth, and Ann Nordgren

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    QTLViewer: an interactive webtool for genetic analysis in the Collaborative Cross and Diversity Outbred mouse populations, Matthew J Vincent, Isabela Gerdes Gyuricza, Gregory R Keele, Daniel Mario Gatti, Mark P. Keller, Karl W. Broman, and Gary Churchill

     

    Quantifying genetic mapping power in a Diversity Outbred mouse population, Jared L. Noel

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    Quantifying interpretation reproducibility in Vision Transformer models with TAVAC., Yue Zhao, Dylan Agyemang, Yang Liu, J Matthew Mahoney, and Sheng Li

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    Rapamycin/metformin co-treatment normalizes insulin sensitivity and reduces complications of metabolic syndrome in type 2 diabetic mice, Peter C. Reifsnyder, Kevin Flurkey, Rosalinda A. Doty, Nigel A. Calcutt, Robert A. Koza, and David E Harrison

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    Rapid changes in plasma corticosterone and medial amygdala transcriptome profiles during social status change reveal molecular pathways associated with a major life history transition in mouse dominance hierarchies., Tyler M Milewski, Won Lee, Rebecca L Young, Hans A Hofmann, and James P Curley

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    Rare disease gene association discovery in the 100,000 Genomes Project., Valentina Cipriani, Letizia Vestito, Emma F Magavern, Julius O B Jacobsen, Gavin Arno, Elijah R Behr, Katherine A Benson, Marta Bertoli, Detlef Bockenhauer, Michael R Bowl, Kate Burley, Li F Chan, Patrick Chinnery, Peter J Conlon, Marcos A Costa, Alice E Davidson, Sally J Dawson, Elhussein A E Elhassan, Sarah E Flanagan, Marta Futema, Daniel P Gale, Sonia García-Ruiz, Cecilia Gonzalez Corcia, Helen R Griffin, Sophie Hambleton, Amy R Hicks, Henry Houlden, Richard S Houlston, Sarah A Howles, Robert Kleta, Iris Lekkerkerker, Siying Lin, Petra Liskova, Hannah H Mitchison, Heba Morsy, Andrew D Mumford, William G Newman, Ruxandra Neatu, Edel A O'Toole, Albert C M Ong, Alistair T Pagnamenta, Shamima Rahman, Neil Rajan, Peter N Robinson, Mina Ryten, Omid Sadeghi-Alavijeh, John A Sayer, Claire L Shovlin, Jenny C Taylor, Omri Teltsh, Ian Tomlinson, Arianna Tucci, Clare Turnbull, Albertien M van Eerde, James S Ware, Laura M Watts, Andrew R Webster, Sarah K Westbury, Sean L Zheng, Mark Caulfield, and Damian Smedley

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    Reconstruction of the human amylase locus reveals ancient duplications seeding modern-day variation., Feyza Yilmaz, Charikleia Karageorgiou, Kwondo Kim, Petar Pajic, Kendra Scheer, Human Genome Structural Variation Consortium, Christine R Beck, Ann-Marie Torregrossa, Charles Lee, and Omer Gokcumen

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    Recruitment, rewiring and deep conservation in flowering plant gene regulation., Leo A Baumgart, Sharon I Greenblum, Abraham Morales-Cruz, Peng Wang, Yu Zhang, Lin Yang, Cindy Chen, David J Dilworth, Alexis Garretson, Nicolas Grosjean, Guifen He, Emily Savage, Yuko Yoshinaga, Ian K Blaby, Chris G Daum, and Ronan C O'Malley

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    Reduced subgenomic RNA expression is a molecular indicator of asymptomatic SARS-CoV-2 infection, Chee-Hong Wong, Chew Yee Ngan, Rachel L Goldfeder, Jennifer Idol, Chris Kuhlberg, Rahul Maurya, Kevin Kelly, Greg Omerza, Nicholas Renzette, Francine De Abreu, Lei Li, Frederick A. Browne, Edison Liu, and Chia-Lin Wei

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    Repeated Measures Latent Dirichlet Allocation for Longitudinal Microbiome Analysis, Namitha Viona Pais, Nalini Ravishanker, Sanguthevar Rajasekaran, and George M. Weinstock

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    Replacing non-biomedical concepts improves embedding of biomedical concepts., Enock Niyonkuru, Mauricio Soto Gomez, Elena Casarighi, Stephan Antogiovanni, Hannah Blau, Justin T Reese, Giorgio Valentini, and Peter N Robinson

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    Reproductive experience drives changes in behaviour and physiology in male California mice, Peromyscus californicus, Maria E. Colt, Priyanka Agarwal, David Kolb, Erica Glasper, and Heidi Fisher

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    Resistin-like molecule γ attacks cardiomyocyte membranes and promotes ventricular tachycardia., Nina Kumowski, Steffen Pabel, Jana Grune, Noor Momin, Van K Ninh, Laura Stengel, Kyle I Mentkowski, Yoshiko Iwamoto, Yi Zheng, I-Hsiu Lee, Jessica Matthias, Jan O Wirth, Fadi E Pulous, Hana Seung, Alexandre Paccalet, Charlotte G Muse, Kenneth K Y Ting, Paul Delgado, Andrew J M Lewis, Vaishali Kaushal, Antonia Kreso, Dennis Brown, Sikander Hayat, Rafael Kramann, Filip K Swirski, Kamila Naxerova, Daniel C Propheter, Lora V Hooper, Michael A Moskowitz, Kevin R King, Nadia Rosenthal, Maarten Hulsmans, and Matthias Nahrendorf

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    Response of cultured primary gingival and periodontal ligament cells to angiotensin II and IL1β challenges., Thais Francini Garbieri, Thiago José Dionísio, Bella Luna Colombini-Ishikiriama, Rafaela Alves da Silva, Vanessa Soares Lara, Sandra Helena Penha Oliveira, Maria Helena Fernandes, Andrew S Greene, and Carlos Ferreira Santos

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    Retinal vascular dysfunction in the Mthfr(677C>T) mouse model of cerebrovascular disease, Alaina M Reagan, Michael MacLean, Travis L Cossette, and Gareth R Howell

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    Retrograde mitochondrial signaling governs the identity and maturity of metabolic tissues., Emily M Walker, Gemma L Pearson, Nathan Lawlor, Ava M Stendahl, Anne Lietzke, Vaibhav Sidarala, Jie Zhu, Tracy Stromer, Emma C Reck, Jin Li, Elena Levi-D'Ancona, Mabelle B Pasmooij, Dre L Hubers, Aaron Renberg, Kawthar Mohamed, Vishal S Parekh, Irina X Zhang, Benjamin Thompson, Deqiang Zhang, Sarah A Ware, Leena Haataja, Nathan Qi, Stephen C J Parker, Peter Arvan, Lei Yin, Brett A Kaufman, Leslie S Satin, Lori Sussel, Michael L. Stitzel, and Scott A Soleimanpour

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    RNA splicing as a biomarker and phenotypic driver of meningioma DNA-methylation groups., Nathan Leclair, Abrar Choudury, William C Chen, Stephen T Magill, Kathleen McCortney, Craig M Horbinski, Zhenhong Chen, Ezequiel Goldschmidt, Charlotte D Eaton, Ketan R Bulsara, Wenya Linda Bi, Akash J Patel, Felix Sahm, David Raleigh, and Olga Anczuków

     

    RSNA 2023 Abdominal Trauma AI Challenge: Review and Outcomes., Sebastiaan Hermans, Zixuan Hu, Robyn L Ball, Hui Ming Lin, Luciano M Prevedello, Ferco H Berger, Ibrahim Yusuf, Jeffrey D Rudie, Maryam Vazirabad, Adam E Flanders, George Shih, John Mongan, Savvas Nicolaou, Brett S Marinelli, Melissa A Davis, Kirti Magudia, Ervin Sejdić, and Errol Colak

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    SAMPLER: unsupervised representations for rapid analysis of whole slide tissue images., Patience Mukashyaka, Todd B Sheridan, Ali Foroughi Pour, and Jeffrey Chuang

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    SARM1 Inhibition in Three Mouse Models of Charcot-Marie-Tooth Disease., Alaura D Rice, Abby Tadenev, Timothy J Hines, Jonathan R Funke, and Robert W. Burgess

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    SARS-CoV-2 induced immune perturbations in infants vary with disease severity and differ from adults' responses., Djamel Nehar-Belaid, Asunción Mejías, Zhaohui Xu, Radu Marches, Rushil Yerrabelli, Guo Chen, Sara Mertz, Fang Ye, Pablo J Sánchez, John S Tsang, Teresa Aydillo, Lisa Miorin, Anastasija Cupic, Adolfo García-Sastre, Duygu Ucar, Jacques Banchereau, Virginia Pascual, and Octavio Ramilo

     

    Schizophrenia-Like Deficits and Impaired Glutamate/Gamma-aminobutyric acid Homeostasis in Zfp804a Conditional Knockout Mice., Qiao-Xia Zhang, Shan-Shan Wu, Peng-Jie Wang, Rui Zhang, Robert K Valenzuela, Shan-Shan Shang, Ting Wan, and Jie Ma

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    Search, The Jackson Laboratory

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    Search, The Jackson Laboratory

     

    Senescence-associated Transcriptomic Signatures and Spatial Localization of Immune Cells in Male and Female Mammalian Hearts, Norah Allam

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    SenNet recommendations for detecting senescent cells in different tissues., Vidyani Suryadevara, Adam D Hudgins, Adarsh Rajesh, Alberto Pappalardo, Alla Karpova, Amit K Dey, Ann Hertzel, Anthony Agudelo, Azucena Rocha, Bikem Soygur, Birgit Schilling, Chase M Carver, Cristina Aguayo-Mazzucato, Darren J Baker, David A Bernlohr, Diana Jurk, Dilyana B Mangarova, Ellen M Quardokus, Elizabeth Ann L Enninga, Elizabeth L Schmidt, Feng Chen, Francesca E Duncan, Francesco Cambuli, Gagandeep Kaur, George A Kuchel, Gung Lee, Heike E Daldrup-Link, Helene Martini, Hemali Phatnani, Iman M Al-Naggar, Irfan Rahman, Jia Nie, João F Passos, Jonathan C Silverstein, Judith Campisi, Julia Wang, Kanako Iwasaki, Karina Barbosa, Kay Metis, Kerem Nernekli, Laura J Niedernhofer, Li Ding, Lichao Wang, Lisa C Adams, Liu Ruiyang, Madison L Doolittle, Marcos G Teneche, Marissa J Schafer, Ming Xu, Mohammadjavad Hajipour, Mozhgan Boroumand, Nathan Basisty, Nicholas Sloan, Nikolai Slavov, Olena Kuksenko, Paul Robson, Paul T Gomez, Periklis Vasilikos, Peter D Adams, Priscila Carapeto, Quan Zhu, Ramalakshmi Ramasamy, Rolando Perez-Lorenzo, Rong Fan, Runze Dong, Ruth R Montgomery, Sadiya Shaikh, Sanja Vickovic, Shanshan Yin, Shoukai Kang, Sonja Suvakov, Sundeep Khosla, Vesna D Garovic, Vilas Menon, Yanxin Xu, Yizhe Song, Yousin Suh, Zhixun Dou, and Nicola Neretti

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    Sex Differences in Molecular Rhythms in the Human Cortex, Ryan W. Logan, Xiangning Xue, Kyle D. Ketchesin, Gabriel Hoffman, Panos Roussos, George Tseng, Colleen A. McClung, and Marianne L. Seney

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    SINE retrotransposons import polyadenylation signals to 3'UTRs in dog (Canis familiaris)., Jessica D Choi, Lelani A Del Pinto, and Nathan B Sutter

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    Single-cell and bulk transcriptional profiling of mouse ovaries reveals novel genes and pathways associated with DNA damage response in oocytes., Monique Mills, Chihiro Emori, Parveen Kumar, Zachary Boucher, Joshy George, and Ewelina Bolcun-Filas

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    Single-cell transcriptomics defines Dot1L interacting partners and downstream target genes in the mouse molar dental pulp, Rosa Guzzo, Badam Enkhmandakh, Timothy Becker, Pujan Joshi, Paul Robson, Anushree Vijaykumar, Mina Mina, Dong-Guk Shin, and Dashzeveg Bayarsaihan

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    Single unit-derived connectivity networks in tuberous sclerosis complex reveal propensity for network hypersynchrony driven by tuber-tuber interactions., Aswin Chari, Amanda E Hernan, J Matthew Mahoney, Rachel Thornton, M Zubair Tahir, Martin M Tisdall, and Rod C Scott

     

    Skin Microbiome Alterations in Skin Diseases, Travis Whitfill, Gilles R. Dubé, and Julia Oh

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    Skin Microbiome Variation with Cancer Progression in Human Cutaneous Squamous Cell Carcinoma., Anita Y Voigt, Akintunde Emiola, Jethro Johnson, Elizabeth Fleming, Hoan Nguyen, Wei Zhou, Kenneth Y Tsai, Christine Fink, and Julia Oh

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    Social status mediated variation in hypothalamic transcriptional profiles of male mice, Won Lee, M F. Dwortz, T M. Milewski, F A. Champagne, and J P. Curley

     

    Spatial transcriptomics for assessing the diabetic kidney, Jingyan Zhang

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    Spatiotemporal metabolic mapping of ex-situ preserved hearts subjected to dialysis by integration of bio-SPME sampling with non-targeted metabolipidomic profiling., Mariola Olkowicz, Frank Yu, Juglans Souto Alvarez, Roberto Vanin Pinto Ribeiro, Roizar Rosales, Liming Xin, Miao Yu, Karol Jaroch, Mitchell Brady Adamson, Ved Bissoondath, Filio Billia, Mitesh Vallabh Badiwala, and Janusz Pawliszyn

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    Spatiotemporal Profiling Defines Persistence and Resistance Dynamics during Targeted Treatment of Melanoma., Jill C Rubinstein, Sergii Domanskyi, Todd B Sheridan, Brian J Sanderson, SungHee Park, Jessica Kaster, Haiyin Li, Olga Anczuków, Meenhard Herlyn, and Jeffrey Chuang

     

    Spatiotemporal Profiling of Patient Derived Xenograft Tumor Microenvironments, Wanying Li

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    Species- and strain-specific microbial modulation of interferon, innate immunity, and epithelial barrier in 2D air-liquid interface respiratory epithelial cultures., Mian Horvath, Ruoyun Xiong, Diana Cadena, Megan Callender, Elizabeth Aiken, Anita Y Voigt, Ryan Caldwell, José Fachi, Blanda Di Luccia, Zoe Scholar, Peter Yu, Andrew Salner, Marco Colonna, Karolina Palucka, and Julia Oh

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    Spectral divergence prioritizes key classes, genes, and pathways shared between substance use disorders and cardiovascular disease., Everest Castaneda, Elissa J Chesler, and Erich Baker

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    Speech and language classification in the human phenotype ontology., Angela T Morgan, Ben D Coleman, Adam P Vogel, Alisdair McNeill, and Peter N Robinson

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    STAMP: Single-cell transcriptomics analysis and multimodal profiling through imaging., Emanuele Pitino, Anna Pascual-Reguant, Felipe Segato-Dezem, Kellie Wise, Irepan Salvador-Martinez, Helena Lucia Crowell, Maycon Marção, Max Ruiz, Elise T Courtois, William F Flynn, Santhosh Sivajothi, Emily Soja, Ginevra Caratù, German Atzin Mora-Roldan, B Kate Dredge, Yutian Liu, Hannah Chasteen, Monika Mohenska, Juan C Nieto, Raymond K H Yip, Ruvimbo D Mishi, José M Polo, Mohmed Abdalfttah, Adrienne E Sullivan, Jasmine T Plummer, Holger Heyn, and Luciano G Martelotto

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    Stathmin-2 enhances motor axon regeneration after injury independent of its binding to tubulin., Melinda S Beccari, Olatz Arnold-Garcia, Michael W Baughn, Jonathan W Artates, Melissa McAlonis-Downes, Jaisen Lim, Dulce Fernanda Leyva-Cázares, Hugo Isaac Rubio-Lara, Andrea Ramirez-Rodriguez, Carol N Bernal-Buenrostro, Brian Murgia-Bay, Carolina K Rangel, Dong Hyun Kim, Ze'ev Melamed, Cathleen Lutz, Clotilde Lagier-Tourenne, Kevin D Corbett, Jone López-Erauskin, and Don W Cleveland

     

    Statistical Power to Detect QTL Peaks in Genetic Modifier Crosses, Justine Chu

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    Steering research on mRNA splicing in cancer towards clinical translation., Olga Anczuków, Frédéric H-T Allain, Brittany Lynn Angarola, Douglas L Black, Angela N Brooks, Chonghui Cheng, Ana Conesa, Edie I Crosse, Eduardo Eyras, Ernesto Guccione, Sydney X Lu, Karla M Neugebauer, Priyanka Sehgal, Xiao Song, Zuzana Tothova, Juan Valcárcel, Kevin M Weeks, Gene W Yeo, and Andrei Thomas-Tikhonenko

     

    Strengthening Insights Into MAMDC2: Functional Characterization Of A Dystrophic Mouse Model, Illeana West

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    STRprofiler: efficient comparisons of short tandem repeat profiles for biomedical model authentication., Jared M Andrews, Michael W Lloyd, Steven Neuhauser, Margaret Bundy, Emily L Jocoy, Susan Airhart, Carol J Bult, Yvonne A Evrard, Jeffrey Chuang, and Suzanne Baker

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    Structural polymorphism and diversity of human segmental duplications., Hyeonsoo Jeong, Philip C Dishuck, DongAhn Yoo, William T Harvey, Katherine M Munson, Alexandra P Lewis, Jennifer Kordosky, Gage H Garcia, Human Genome Structural Variation Consortium (HGSVC), Feyza Yilmaz, Pille Hallast, Charles Lee, Tomi Pastinen, and Evan E Eichler

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    Structures of ATP-binding cassette transporter ABCC1 reveal the molecular basis of cyclic dinucleotide cGAMP export., Omkar Shinde, Joshua A Boyer, Stephanie Cambier, Jordyn J VanPortfliet, Xuewu Sui, Gaya P Yadav, Elizabeth G Viverette, Mario J Borgnia, A Phillip West, Qi Zhang, Daniel B Stetson, and Pingwei Li

     

    Studying the Effect of Cancer-Associated-Fibroblasts on Colorectal Cancer Organoid Growth and Phenotype, Payton Noe

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    Survivorship from pediatric and adult brain tumors: The 2024 Brain Tumor Epidemiology Consortium meeting report., Scott L Coven, Roberta McKean-Cowdin, Michael E Scheurer, Kimberly J Johnson, Luc Bauchet, Carol Kruchko, Ching C Lau, Quinn T Ostrom, John Villano, Yan Yuan, and Friederike Erdmann

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    Sustained Lung Inflammation Post-SARS-CoV-2 Infection in Mice Is Associated with Increased Pulmonary T Cells., Sophie Y Guan, Patricia P Ogger, Ana Farias, Minerva Garcia Martín, Joy Nakawesi, Olivia Bedard, Candice N Baker, Nadia Rosenthal, and Cecilia Johansson

     

    Synaptic Remodeling in Alzheimer’s Disease Alters the Input-Output Properties of Pyramidal Neurons, Katherine W. Sanderson

     

    Syntactic Grooming Classification in Mice with Computer Vision, Cayson Hamilton

     

    Systematic evaluation of how Hand2 dimerization partners regulate DNA binding specificity and biological activity, Mia I. Crawford

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    Systematic ocular phenotyping of 8,707 knockout mouse lines identifies genes associated with abnormal corneal phenotypes., Peter Vo, Denise M Imai-Leonard, Benjamin Yang, Andrew Briere, Andy Shao, M Isabel Casanova, David Adams, Takanori Amano, Oana Amarie, Zorana Berberovic, Lynette Bower, Robert E Braun, Steve Brown, Samantha Burrill, Soo Young Cho, Sharon Clementson-Mobbs, Abigail D'Souza, Mary Dickinson, Mohammad Eskandarian, Ann M Flenniken, Helmut Fuchs, Valerie Gailus-Durner, Jason Heaney, Yann Hérault, Martin Hrabe de Angelis, Chih-Wei Hsu, Shundan Jin, Russell Joynson, Yeon Kyung Kang, Haerim Kim, Hiroshi Masuya, Hamid Meziane, Stephen A Murray, Ki-Hoan Nam, Hyuna Noh, Lauryl M J Nutter, Marcela Palkova, Jan Prochazka, Miles Joseph Raishbrook, Fabrice Riet, Jennifer L Ryan, Jason Salazar, Zachery Seavey, John Richard Seavitt, Radislav Sedlacek, Mohammed Selloum, Kyoung Yul Seo, Je Kyung Seong, Hae-Sol Shin, Toshihiko Shiroishi, Michelle Stewart, Karen L. Svenson, Masaru Tamura, Heather Tolentino, Uchechukwu Udensi, Sara Wells, Jacqueline K White, Amelia M Willett, Janine M Wotton, Wolfgang Wurst, Atsushi Yoshiki, Louise Lanoue, K C Kent Lloyd, Brian C Leonard, Michel J Roux, Colin McKerlie, and Ala Moshiri

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    Systematic Ocular Phenotyping of Knockout Mouse Lines Identifies Genes Associated With Age-Related Corneal Dystrophies., Andrew Briere, Peter Vo, Benjamin Yang, David Adams, Takanori Amano, Oana Amarie, Zorana Berberovic, Lynette Bower, Steve D M Brown, Samantha Burrill, Soo Young Cho, Sharon Clementson-Mobbs, Abigail D'souza, Mohammad Eskandarian, Ann M Flenniken, Helmut Fuchs, Valerie Gailus-Durner, Yann Hérault, Martin Hrabe de Angelis, Shundan Jin, Russell Joynson, Yeon Kyung Kang, Haerim Kim, Hiroshi Masuya, Hamid Meziane, Ki-Hoan Nam, Hyuna Noh, Lauryl M J Nutter, Marcela Palkova, Jan Prochazka, Miles Joseph Raishbrook, Fabrice Riet, Jason Salazar, Radislav Sedlacek, Mohammed Selloum, Kyoung Yul Seo, Je Kyung Seong, Hae-Sol Shin, Toshihiko Shiroishi, Michelle Stewart, Karen L. Svenson, Masaru Tamura, Heather Tolentino, Sara Wells, Wolfgang Wurst, Atsushi Yoshiki, Louise Lanoue, K C Kent Lloyd, Brian C Leonard, Michel J Roux, Colin McKerlie, and Ala Moshiri

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    Systematic optimization and prediction of cre recombinase for precise genome editing in mice., Valerie Erhardt, Elli I Hartig, Kristian Lorenzo, Hannah R Megathlin, Basile Tarchini, and Vishnu Hosur

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    Systems genetics reveals the influence of expression QTLs in mouse embryonic stem cells on transcriptional variation later in differentiated neural progenitor cells., Selcan Aydin, Daniel A Skelly, Hannah B Dewey, J Matthew Mahoney, Ted Choi, Laura G Reinholdt, Christopher L. Baker, and Steven C. Munger

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    System vaccinology analysis of predictors and mechanisms of antibody response durability to multiple vaccines in humans., Mario Cortese, Thomas Hagan, Nadine Rouphael, Sheng-Yang Wu, Xia Xie, Dmitri Kazmin, Florian Wimmers, Shakti Gupta, Robbert van der Most, Margherita Coccia, Prabhu S Aranuchalam, Helder I Nakaya, Yating Wang, Elizabeth Coyle, Shu Horiuchi, Hanchih Wu, Mary Bower, Aneesh Mehta, Clifford Gunthel, Steve E Bosinger, Yuri Kotliarov, Foo Cheung, Pamela L Schwartzberg, Ronald N Germain, John Tsang, Shuzhao Li, Randy Albrecht, Hideki Ueno, Shankar Subramaniam, Mark J Mulligan, Surender Khurana, Hana Golding, and Bali Pulendran

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    Targeting immune-fibroblast cell communication in heart failure., Junedh M Amrute, Xin Luo, Vinay Penna, Steven Yang, Tracy Yamawaki, Sikander Hayat, Andrea Bredemeyer, In-Hyuk Jung, Farid F Kadyrov, Gyu Seong Heo, Rajiu Venkatesan, Sally Yu Shi, Alekhya Parvathaneni, Andrew L Koenig, Christoph Kuppe, Candice N Baker, Hannah Luehmann, Cameran Jones, Benjamin Kopecky, Xue Zeng, Tore Bleckwehl, Pan Ma, Paul Lee, Yuriko Terada, Angela Fu, Milena Furtado, Daniel Kreisel, Atilla Kovacs, Nathan O Stitziel, Simon Jackson, Chi-Ming Li, Yongjian Liu, Nadia Rosenthal, Rafael Kramann, Brandon Ason, and Kory J Lavine

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    Targeting Ion Channels: Blockers Suppress Calcium Signals and Induce Cytotoxicity Across Medulloblastoma Cell Models., Darani Ashley Thammavongsa, Taylor N Jackvony, Markus J Bookland, and Min D Tang-Schomer

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    TEAL-Seq: targeted expression analysis sequencing., Georgia Doing, Priya Shanbhag, Isaac Bell, Sara Cassidy, Efthymios Motakis, Elizabeth Aiken, Julia Oh, and Mark D Adams

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    Testing SIPA1L2 as a modifier of CMT1A using mouse models., George Murray, Timothy J Hines, Abby Tadenev, Isaac Xu, Stephan Züchner, and Robert W. Burgess

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    TET2-Mutant Clonal Hematopoiesis Promotes Heart Failure With Preserved Ejection Fraction., Ambarish Pandey, Toby Thomas, Yuanyuan Ji, Benjamin Kroger, Peter Carlsgaard, Camila I Irion, Fatma Kalkan, Matthew Segar, Vinayak Subramanian, Antoni Bayés-Genís, Albert Son, Kira Young, Jennifer J. Trowbridge, Naveen Premnath, Nan Jiang, Daniel Daou, Wenhuo Hu, Sarah A Ware, Dan Tong, and Stephen S Chung

     

    The 2023 medical genetics workforce in the United States., Megan Lyon, Deborah Maiese, Miriam G Blitzer, Rhonda West, Vivian Pan, Cinthya Zepeda Mendoza, Laurie M Connors, Beth Ogata, Erin MacLeod, Nguyen Park, Marci K Sontag, Molly Caisse, Mathew J Edick, Sylvia Mann, Kunal Sanghavi, Joann Bodurtha, and Workgroup NCCMGW

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    The BIM deletion polymorphism potentiates the survival of leukemia stem and progenitor cells and impairs response to targeted therapies., Mengge Yu, Giselle Sek Suan Nah, Vaidehi Krishnan, Fatin Nasha Bte Sulaimi, King Pan Ng, Chuqi Wang, Shruti Bhatt, Charles Chuah, David E. Bergstrom, and S Tiong Ong

     

    The Calcium Binding Gene Calb1 is an FGF23 target in Distal Convoluted Tubule in Sickle Cell Disease, Grace Z. Xie

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    The Cardiac Sarcomere and Cell Cycle, Anthony M. Pettinato, Feria A. Ladha, and J Travis Hinson

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    The CD123 antibody-drug conjugate pivekimab sunirine exerts profound activity in preclinical models of pediatric acute lymphoblastic leukemia., Ben Watts, Christopher M Smith, Kathryn Evans, Andrew J Gifford, Sara M A Mohamed, Stephen W Erickson, Eric J Earley, Steven Neuhauser, Timothy M Stearns, Vivek M. Philip, Jeffrey Chuang, Patrick A Zweidler-McKay, Sribalaji Lakshmikanthan, Emily L Jocoy, Carol J Bult, Beverly A Teicher, Malcolm A Smith, and Richard B Lock

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    The ClinGen Syndromic Disorders Gene Curation Expert Panel: Assessing the Clinical Validity of 111 Gene-Disease Relationships., Eleanor Broeren, Vanessa Gitau, Alicia Byrne, Pamela Ajuyah, Marie Balzotti, Jonathan Berg, Krista Bluske, B Monica Bowen, Matthew P Brown, Amanda Buchanan, Brendan Burns, Nicole J Burns, Anjana Chandrasekhar, Aditi Chawla, Jessica Chong, Maya Chopra, Amanda Clause, Marina DiStefano, Stephanie DiTroia, Marwa Elnagheeb, Amanda Girod, Himanshu Goel, Katie Golden-Grant, Thuong Ha, Ada Hamosh, Jennifer Huang, Madeline Hughes, Saumya Jamuar, Sylvia Kam, Akanchha Kesari, Ai Ling Koh, Rhonda Lassiter, Sarah Leigh, Gabrielle Lemire, Jiin Ying Lim, Alka Malhotra, Hannah McCurry, Becky Milewski, Shahida Moosa, Stephen A Murray, Emma Owens, Emma Palmer, Brooke Palus, Mayher Patel, Revathi Rajkumar, Julie Ratliff, F Lucy Raymond, Bruno Della Ripa Rodrigues Assis, Samin Sajan, Zinayida Schlachetzki, Sarah Schmidt, Zornitza Stark, Samuel Strom, Julie Taylor, Courtney Thaxton, Devon Thrush, Sabrina Toro, Kezang Tshering, Nicole Vasilevsky, Bess Wayburn, Ryan Webb, Anne O'Donnell-Luria, and Alison J Coffey

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    The contribution of de novo coding mutations to meningomyelocele., Yoo-Jin Jiny Ha, Ashna Nisal, Isaac Tang, Chanjae Lee, Ishani Jhamb, Cassidy Wallace, Robyn Howarth, Sarah Schroeder, Keng Ioi Vong, Naomi Meave, Fiza Jiwani, Chelsea Barrows, Sangmoon Lee, Nan Jiang, Arzoo Patel, Krisha Bagga, Niyati Banka, Liana Friedman, Francisco A Blanco, Seyoung Yu, Soeun Rhee, Hui Su Jeong, Isaac Plutzer, Michael B Major, Béatrice Benoit, Christian Poüs, Caleb Heffner, Zoha Kibar, Gyang Markus Bot, Hope Northrup, Kit Sing Au, Madison Strain, Allison E Ashley-Koch, Richard H Finnell, Joan T Le, Hal S Meltzer, Camila Araujo, Helio R Machado, Roger E Stevenson, Anna Yurrita, Sara Mumtaz, Awais Ahmed, Mulazim Hussain Khara, Osvaldo M Mutchinick, José Ramón Medina-Bereciartu, Friedhelm Hildebrandt, Gia Melikishvili, Ahmed I Marwan, Valeria Capra, Mahmoud M Noureldeen, Aida M S Salem, Mahmoud Y Issa, Maha S Zaki, Libin Xu, Ji Eun Lee, Donghyuk Shin, Anna Alkelai, Alan R Shuldiner, Stephen F Kingsmore, Stephen A Murray, Heon Yung Gee, W Todd Miller, Kimberley F Tolias, John B Wallingford, Spina Bifida Sequencing Consortium, Sangwoo Kim, and Joseph G Gleeson

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    The impact of co-housing on murine aging studies., Alison Luciano and Gary Churchill

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    The impact of co-housing on murine aging studies., Alison Luciano and Gary Churchill

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    The integrative genomic and functional immunological analyses of colorectal cancer initiating cells to modulate stemness properties and the susceptibility to immune responses., Issam Tout, Salim Bougarn, Mohammed Toufiq, Neha Gopinath, Ola Hussein, Abbirami Sathappan, Evonne Chin-Smith, Fazulur Rehaman, Rebecca Mathew, Lisa Mathew, Kun Wang, Li Liu, Abdulrahman Salhab, Oleksandr Soloviov, Sara Tomei, Waseem Hasan, Sahar Da'as, Yosra Bejaoui, Nady El Hajj, Karama Makni Maalej, Said Dermime, Kakil Rasul, Paolo Dellabona, Giulia Casorati, Alice Turdo, Matilde Todaro, Giorgio Stassi, Soldano Ferrone, Xinhui Wang, and Cristina Maccalli

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    The metabolic basis of cancer-related fatigue., Robert Dantzer, Brandon Chelette, Elisabeth G Vichaya, A Phillip West, and Aaron Grossberg

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    The Missing Half: Why Sex Differences Matter in Alzheimer's Disease., Kristen M S O'Connell

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    The multilayered transcriptional architecture of glioblastoma ecosystems., Masashi Nomura, Avishay Spitzer, Kevin C Johnson, Luciano Garofano, Djamel Nehar-Belaid, Noam Galili Darnell, Alissa C Greenwald, Lillian Bussema, Young Taek Oh, Frederick S Varn, Fulvio D'Angelo, Simon Gritsch, Kevin J Anderson, Simona Migliozzi, L Nicolas Gonzalez Castro, Tamrin ChowdhFury, Nicolas Robine, Catherine Reeves, Jong Bae Park, Anuja Lipsa, Frank Hertel, Anna Golebiewska, Simone P Niclou, Labeeba Nusrat, Sorcha Kellet, Sunit Das, Hyo Eun Moon, Sun Ha Paek, Franck Bielle, Alice Laurenge, Anna Luisa Di Stefano, Bertrand Mathon, Alberto Picca, Marc Sanson, Shota Tanaka, Nobuhito Saito, David M Ashley, Stephen T Keir, Keith L Ligon, Jason T Huse, W K Alfred Yung, Anna Lasorella, Roel G W Verhaak, Antonio Iavarone, Mario L Suvà, and Itay Tirosh

     

    The phenotypic impact of CSF1R enhancer fms-intronic regulatory element (FIRE) deletion in NSG mice, Zoë A. Galvin

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    The primate gut microbiota contributes to interspecific differences in host metabolism., Elizabeth K Mallott, Sahana Kuthyar, Won Lee, Derek Reiman, Hongmei Jiang, Sriram Chitta, E Alexandria Waters, Brian T Layden, Ronen Sumagin, Laura D Manzanares, Guan-Yu Yang, Maria Luisa Savo Sardaro, Stanton Gray, Lawrence E Williams, Yang Dai, James P Curley, Chad R Haney, Emma R Liechty, Christopher W Kuzawa, and Katherine R Amato

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    The rare-to-common disease journey: a winding road to new therapies., Laura G Reinholdt, Elissa J Chesler, Martin Pera, and Nadia Rosenthal

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    The RSNA Abdominal Traumatic Injury CT (RATIC) Dataset., Jeffrey D Rudie, Hui-Ming Lin, Robyn L Ball, Sabeena Jalal, Luciano M Prevedello, Savvas Nicolaou, Brett S Marinelli, Adam E Flanders, Kirti Magudia, George Shih, Melissa A Davis, John Mongan, Peter D Chang, Ferco H Berger, Sebastiaan Hermans, Meng Law, Tyler Richards, Jan-Peter Grunz, Andreas Steven Kunz, Shobhit Mathur, Sandro Galea-Soler, Andrew D Chung, Saif Afat, Chin-Chi Kuo, Layal Aweidah, Ana Villanueva Campos, Arjuna Somasundaram, Felipe Antonio Sanchez Tijmes, Attaporn Jantarangkoon, Leonardo Kayat Bittencourt, Michael Brassil, Ayoub El Hajjami, Hakan Dogan, Muris Becircic, Agrahara G Bharatkumar, Eduardo Moreno Júdice de Mattos Farina, Errol Colak, Dataset Curator Group, Dataset Contributor Group, and Dataset Annotator Group

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    The Tsallis generalized entropy enhances the interpretation of transcriptomics datasets, Nicolas Dérian, Hang-Phuong Pham, Djamel Nehar-Belaid, Nicolas Tchitchek, David Klatzmann, Vicaut Eric, and Adrien Six

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    The Unified Phenotype Ontology : a framework for cross-species integrative phenomics., Nicolas Matentzoglu, Susan M. Bello, Ray Stefancsik, Sarah M Alghamdi, Anna V Anagnostopoulos, James P Balhoff, Meghan A Balk, Yvonne M Bradford, Yasemin Bridges, Tiffany J Callahan, Harry Caufield, Alayne Cuzick, Leigh Carmody, Anita R Caron, Vinicius de Souza, Stacia R Engel, Petra Fey, Malcolm Fisher, Sarah Gehrke, Christian Grove, Peter Hansen, Nomi L Harris, Midori A Harris, Laura Harris, Arwa Ibrahim, Julius O B Jacobsen, Sebastian Köhler, Julie A McMurry, Violeta Munoz-Fuentes, Monica C Munoz-Torres, Helen Parkinson, Zoë M Pendlington, Clare Pilgrim, Sofia M C Robb, Peter N Robinson, James Seager, Erik Segerdell, Damian Smedley, Elliot Sollis, Sabrina Toro, Nicole Vasilevsky, Valerie Wood, Melissa A Haendel, Christopher J Mungall, James A McLaughlin, and David Osumi-Sutherland

     

    The use of AI to Predict Immune Subtype from Tumor Images, Lauren E. Powers

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    Tipping the balance: innate and adaptive immunity in mitochondrial disease., A Phillip West and Peter J McGuire

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    TLR4 deficiency does not alter glaucomatous progression in a mouse model of chronic glaucoma., Chi Zhang, Marina Simón, Jeffrey M. Harder, Haeyn Lim, Christa Montgomery, Qing Wang, and Simon W M John

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    Transcripts with high distal heritability mediate genetic effects on complex metabolic traits., Anna L. Tyler, J Matthew Mahoney, Mark P Keller, Candice N Baker, Margaret Gaca, Anuj Srivastava, Isabela Gerdes Gyuricza, Madeleine J Braun, Nadia Rosenthal, Alan D Attie, Gary Churchill, and Gregory W. Carter

     

    TRP Channels in Excitotoxicity., Pengyu Zong, Nicholas Legere, Jianlin Feng, and Lixia Yue

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    TRPM2 overactivation drives hyperlipidemia-induced dysfunction of myeloid cells and neurovascular units., Pengyu Zong, Cindy Li, Jianlin Feng, Zhichao Yue, Nicholas Legere, Albert S Yu, Fahad Shah, Adrianna Perez, Zhu Li, Evan Jellison, Yasuo Mori, Barbara Miller, Rajkumar Verma, Bruce Liang, and Lixia Yue

     

    Tumor Immune Microenvironment in Humanized NSG-SGM3 Mice with Breast Cancer Undergo HER2 Chimeric Antigen Receptor T Cell Therapy, Sarah Guo

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    Type I IFN drives unconventional IL-1β secretion in lupus monocytes., Simone Caielli, Preetha Balasubramanian, Juan Rodriguez-Alcazar, Uthra Balaji, Lauren Robinson, Zurong Wan, Jeanine Baisch, Cynthia Smitherman, Lynnette Walters, Paola Sparagana, Djamel Nehar-Belaid, Radu Marches, Lorien Nassi, Katie Stewart, Julie Fuller, Jacques F Banchereau, Jinghua Gu, Tracey Wright, and Virginia Pascual

     

    Understanding the Growth of Xenografted Tumors, Ashley Kuczmera

     

    Unsupervised Machine Learning for Visual Frailty Prediction in Mice, Dustin M. Miao

     

    Using Deep Learning Approaches to Quantify Behavioral Changes in Normal Aging and Alzheimer's Disease Mouse Models, Namyanzi S.E. Edwards

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    Using genome-wide expression compendia to study microorganisms, Alexandra J. Lee, Taylor Reiter, Georgia Doing, Julia Oh, Deborah A. Hogan, and Casey S. Greene

     

    Using machine learning to classify subtypes of rhabdomyosarcoma, Jingyan Zhang

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    Using paired-end read orientations to assess technical biases in capture Hi-C., Peter Hansen, Hannah Blau, Jochen Hecht, Guy Karlebach, Alexander Krannich, Robin Steinhaus, Matthias Truss, and Peter N Robinson

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    Validation studies of the ParaDNA, Min Li, Ruiyang Tao, Wei Zhou, Yanan Li, Meng Meng, Yilun Zhang, Linsheng Yu, Liqin Chen, Yingnan Bian, and Chengtao Li

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    Virtual Cancer Genomics: An Accessible and Effective Approach to Research Training for Undergraduates., Erica L Gerace and Sarah Wojiski

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    Workplace perk or pitfall? A qualitative study of genetic counselors' perspectives and experiences with workplace genetic testing., Elizabeth Charnysh, Katherine Hendy, Kerry Ryan, Anya E R Prince, W Gregory Feero, Alyx Vogle, Sarah McCain, Alexandra Truhlar, J Scott Roberts, Charles Lee, Kunal Sanghavi, Wendy R Uhlmann, and the INSIGHT @ Work Consortium

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    Workshop Report-Heterogeneity and Successful Aging Part I: Heterogeneity in Aging-Challenges and Opportunities., George A Kuchel, Andrea L Hevener, J Graham Ruby, Paola Sebastiani, and Vivek Kumar

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    Workshop Report-Heterogeneity and Successful Aging Part II: Approaches to Investigate Heterogeneity in Aging Research., Vivek Kumar, Andrea L Hevener, J Graham Ruby, Paola Sebastiani, George A Kuchel, and Participants of the NIA Heterogeneity and Successful Aging Workshop

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    Worldwide Innovative Network (WIN) Consortium in Personalized Cancer Medicine: Bringing next-generation precision oncology to patients., Wafik S El-Deiry, Catherine Bresson, Fanny Wunder, Benedito A Carneiro, Don S Dizon, Jeremy L Warner, Stephanie L Graff, Christopher G Azzoli, Eric T Wong, Liang Cheng, Sendurai A Mani, Howard P Safran, Casey Williams, Tobias Meissner, Benjamin Solomon, Eitan Rubin, Angel Porgador, Guy Berchem, Pierre Saintigny, Amir Onn, Jair Bar, Raanan Berger, Manon Gantenbein, Zhen Chen, Cristiano de Pádua Souza, Rui Manuel Vieira Reis, Marina Sekacheva, Andrés Cervantes, William L Dahut, Christina M Annunziata, Kerri Gober, Khaled M Musallam, Humaid O Al-Shamsi, Ibrahim Abu-Gheida, Ramon Salazar, Sewanti Limaye, Adel T Aref, Roger R Reddel, Mohammed Ussama Al Homsi, Abdul Rouf, Said Dermime, Jassim Al Suwaidi, Catalin Vlad, Rares Buiga, Amal Al Omari, Hikmat Abdel-Razeq, Luis F Oñate-Ocaña, Finn Cilius Nielsen, Leah C. Graham, Jens Rueter, Anthony M Joshua, Eugenia Girda, Steven Libutti, Gregory Riedlinger, Mohammed E Salem, Carol J Farhangfar, Ruben A Mesa, Bishoy M Faltas, Olivier Elemento, C S Pramesh, Manju Sengar, Satoru Aoyama, Sadakatsu Ikeda, Ioana Berindan-Neagoe, Himabindu Gaddipati, Mandar Kulkarni, Elisabeth Auzias, Maria Gerogianni, Nicolas Wolikow, Simon Istolainen, Pessie Schlafrig, Naftali Z Frankel, Amanda R Ferraro, Jim Palma, Alejandro Piris Gimenez, Alberto Hernando-Calvo, Enriqueta Felip, Apostolia M Tsimberidou, Roy S Herbst, Josep Tabernero, Richard L Schilsky, Jia Liu, Yves Lussier, Jacques Raynaud, Gerald Batist, Shai Magidi, and Razelle Kurzrock

    Link

    Your Blood is Out for Delivery: Considerations of Shipping Time and Temperature on Degradation of RNA from Stabilized Whole Blood., Filip Stefanovic, Lauren G Brown, James MacDonald, Theo Bammler, Darawan Rinchai, Serena Nguyen, Yuting Zeng, Victoria Shinkawa, Karen Adams, Damien Chaussabel, Erwin Berthier, Amanda J Haack, and Ashleigh B Theberge

 
 
 

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