Submissions from 2021
Targeting antioxidant enzymes enhances the therapeutic efficacy of the BCL-X, Yumi Oh, Hae Rim Jung, Seoyeon Min, Jinjoo Kang, Dongjun Jang, Seungjae Shin, Jiwon Kim, Sang Eun Lee, Chang Ohk Sung, Won-Suk Lee, Charles Lee, Eui Man Jeong, and Sung-Yup Cho
Spatial and temporal expression of PORCN is highly dynamic in the developing mouse cochlea., Brianna L Oliver, Caryl A Young, and Vidhya Munnamalai
Sox2 controls neural stem cell self-renewal through a Fos-centered gene regulatory network., Miriam Pagin, Mattias Pernebrink, Simone Giubbolini, Cristiana Barone, Gaia Sambruni, Yanfen Zhu, Matteo Chiara, Sergio Ottolenghi, Giulio Pavesi, Chia-Lin Wei, Claudio Cantù, and Silvia K Nicolis
FOS Rescues Neuronal Differentiation of Sox2-Deleted Neural Stem Cells by Genome-Wide Regulation of Common SOX2 and AP1(FOS-JUN) Target Genes., Miriam Pagin, Mattias Pernebrink, Mattia Pitasi, Federica Malighetti, Chew Yee Ngan, Sergio Ottolenghi, Giulio Pavesi, Claudio Cantù, and Silvia K Nicolis
Fasting blood glucose as a predictor of mortality: Lost in translation., Dushani L Palliyaguru, Eric J Shiroma, John K Nam, Eleonora Duregon, Camila Vieira Ligo Teixeira, Nathan L Price, Michel Bernier, Simonetta Camandola, Kelli L Vaughan, Ricki J Colman, Andrew Deighan, Ron Korstanje, Luanne L. Peters, Stephanie L Dickinson, Keisuke Ejima, Eleanor M Simonsick, Lenore J Launer, Chee W Chia, Josephine Egan, David B Allison, Gary A Churchill, Rozalyn M Anderson, Luigi Ferrucci, Julie A Mattison, and Rafael de Cabo
Multi-omic and multi-species meta-analyses of nicotine consumption., Rohan H C Palmer, Chelsie E Benca-Bachman, Spencer B Huggett, Jason A. Bubier, John E McGeary, Nikhil Ramgiri, Jenani Srijeyanthan, Jingjing Yang, Peter M Visscher, Jian Yang, Valerie S Knopik, and Elissa J Chesler
Integration of evidence across human and model organism studies: A meeting report., Rohan H C Palmer, Emma C Johnson, Hyejung Won, Renato Polimanti, Manav Kapoor, Apurva Chitre, Molly A. Bogue, Chelsie E Benca-Bachman, Clarissa C Parker, Anurag Verma, Timothy Reynolds, Jason Ernst, Michael Bray, Soo Bin Kwon, Dongbing Lai, Bryan C Quach, Nathan C Gaddis, Laura Saba, Hao Chen, Michael Hawrylycz, Shan Zhang, Yuan Zhou, Spencer Mahaffey, Christian Fischer, Sandra Sanchez-Roige, Anita Bandrowski, Qing Lu, Li Shen, Vivek M. Philip, Joel Gelernter, Laura J Bierut, Dana B Hancock, Howard J Edenberg, Eric O Johnson, Eric J Nestler, Peter B Barr, Pjotr Prins, Desmond J Smith, Schahram Akbarian, Thorgeir Thorgeirsson, David O Walton, Erich Baker, Daniel Jacobson, Abraham A Palmer, Michael Miles, Elissa J Chesler, Jake Emerson, Arpana Agrawal, Maryann Martone, and Robert W Williams
FANCM regulates repair pathway choice at stalled replication forks., Arvind Panday, Nicholas A Willis, Rajula Elango, Francesca Menghi, Erin E Duffey, Edison Liu, and Ralph Scully
MetaboAnalyst 5.0: narrowing the gap between raw spectra and functional insights., Zhiqiang Pang, Jasmine Chong, Guangyan Zhou, David Anderson de Lima Morais, Le Chang, Michel Barrette, Carol Gauthier, Pierre-Étienne Jacques, Shuzhao Li, and Jianguo Xia
A New Twist: The Combination of Sulbactam/Avibactam Enhances Sulbactam Activity against Carbapenem-Resistant, Fernando Pasteran, Jose Cedano, Michelle Baez, Ezequiel Albornoz, Melina Rapoport, Jose Osteria, Sabrina Montaña, Casin Le, Grace Ra, Robert A Bonomo, Marcelo E Tolmasky, Mark D Adams, Alejandra Corso, and Maria Soledad Ramirez
The Mafb cleft-associated variant H131Q is not required for palatogenesis in the mouse., Brian J Paul, Kristina Palmer, Lindsey Rhea, Melissa Carlson, Jocelyn Sharp, C Herbert Pratt, Stephen A Murray, and Martine Dunnwald
A modular master regulator landscape controls cancer transcriptional identity., Evan O Paull, Alvaro Aytes, Sunny J Jones, Prem S Subramaniam, Federico M Giorgi, Eugene F Douglass, Somnath Tagore, Brennan Chu, Alessandro Vasciaveo, Siyuan Zheng, Roel G W Verhaak, Cory Abate-Shen, Mariano J Alvarez, and Andrea Califano
Introduction to mammalian genome special issue: the microbiome in human health and disease., Guillaume Pavlovic, Je Kyung Seong, and George M. Weinstock
The exploration of pluripotency space: Charting cell state transitions in peri-implantation development., Martin Pera and Janet Rossant
Sarcomere function activates a p53-dependent DNA damage response that promotes polyploidization and limits in vivo cell engraftment., Anthony M Pettinato, Dasom Yoo, Jennifer VanOudenhove, Yu-Sheng Chen, Rachel Cohn, Feria A Ladha, Xiulan Yang, Ketan Thakar, Robert Romano, Nicolas Legere, Emily Meredith, Paul Robson, Michael Regnier, Justin L Cotney, Charles E Murry, and J Travis Hinson
Confirmation of a Causal Taar1 Allelic Variant in Addiction-Relevant Methamphetamine Behaviors, Tamara J Phillips, Tyler A. Roy, Sara J Aldrich, Harue Baba, Jason Erk, John R K Mootz, Cheryl Reed, and Elissa J Chesler
Fibroblasts: Origins, definitions, and functions in health and disease., Maksim V Plikus, Xiaojie Wang, Sarthak Sinha, Elvira Forte, Sean M Thompson, Erica L Herzog, Ryan R Driskell, Nadia Rosenthal, Jeff Biernaskie, and Valerie Horsley
Decreased glucocerebrosidase activity and substrate accumulation of glycosphingolipids in a novel GBA1 D409V knock-in mouse model., Nicole K Polinski, Terina N Martinez, Alexander Gorodinsky, Ralph Gareus, Michael Sasner, Mark Herberth, Robert Switzer, Syed O Ahmad, Mali Cosden, Monika Kandebo, Robert E Drolet, Peter D Buckett, Weisong Shan, Yi Chen, Lee J Pellegrino, Gregory D Ellsworth, Leo B Dungan, Warren D Hirst, Sean W Clark, and Kuldip D Dave
Fully phased human genome assembly without parental data using single-cell strand sequencing and long reads., David Porubsky, Peter Ebert, Peter A Audano, Mitchell R Vollger, William T Harvey, Pierre Marijon, Jana Ebler, Katherine M Munson, Melanie Sorensen, Arvis Sulovari, Marina Haukness, Maryam Ghareghani, Human Genome Structural Variation Consortium, Peter M Lansdorp, Benedict Paten, Scott E Devine, Ashley D Sanders, Charles Lee, Mark J P Chaisson, Jan O Korbel, Evan E Eichler, and Tobias Marschall
Differential effects of two catalytic mutations on full-length PRDM9 and its isolated PR/SET domain reveal a case of pseudomodularity., Natalie Powers, Timothy Billings, Kenneth Paigen, and Petko M. Petkov
RNA-Seq reveals changes in human placental metabolism, transport and endocrinology across the first-second trimester transition., Malwina Prater, Russell S Hamilton, Hong Wa Yung, Andrew M Sharkey, Paul Robson, N Erlyani Abd Hamid, Eric Jauniaux, D Stephen Charnock-Jones, Graham J Burton, and Tereza Cindrova-Davies
AAV9-mediated FIG4 delivery prolongs life span in Charcot-Marie-Tooth disease type 4J mouse model., Maximiliano Presa, Rachel M Bailey, Crystal Davis, Tara Murphy, Jenn Cook, Randy Walls, Hannah Wilpan, Laurent P. Bogdanik, Guy M Lenk, Robert W. Burgess, Steven J Gray, and Cathleen Lutz
Hyperexcitability and Pharmacological Responsiveness of Cortical Neurons Derived from Human iPSCs Carrying Epilepsy-Associated Sodium Channel Nav1.2-L1342P Genetic Variant., Zhefu Que, Maria I Olivero-Acosta, Jingliang Zhang, Muriel Eaton, Anke M Tukker, Xiaoling Chen, Jiaxiang Wu, Junkai Xie, Tiange Xiao, Kyle Wettschurack, Layan Yunis, J Marshall Shafer, James A Schaber, Jean-Christophe Rochet, Aaron B Bowman, Chongli Yuan, Zhuo Huang, Chang-Deng Hu, Darci J Trader, William C Skarnes, and Yang Yang
Tackling neurodegenerative diseases with genomic engineering: A new stem cell initiative from the NIH., Daniel M Ramos, William C Skarnes, Andrew B Singleton, Mark R Cookson, and Michael E Ward
Supervised learning with word embeddings derived from PubMed captures latent knowledge about protein kinases and cancer., Vida Ravanmehr, Hannah Blau, Luca Cappelletti, Tommaso Fontana, Leigh Carmody, Ben D Coleman, Joshy George, Justin Reese, Marcin Joachimiak, Giovanni Bocci, Peter Hansen, Carol J Bult, Jens Rueter, Elena Casiraghi, Giorgio Valentini, Christopher Mungall, Tudor I Oprea, and Peter N Robinson
Single-cell longitudinal analysis of SARS-CoV-2 infection in human airway epithelium identifies target cells, alterations in gene expression, and cell state changes., Neal G Ravindra, Mia Madel Alfajaro, Victor Gasque, Nicholas C Huston, Han Wan, Klara Szigeti-Buck, Yuki Yasumoto, Allison M Greaney, Victoria Habet, Ryan D Chow, Jennifer S Chen, Jin Wei, Renata B Filler, Bao Wang, Guilin Wang, Laura E Niklason, Ruth R Montgomery, Stephanie C Eisenbarth, Sidi Chen, Adam Williams, Akiko Iwasaki, Tamas L Horvath, Ellen F Foxman, Richard W Pierce, Anna Marie Pyle, David van Dijk, and Craig B Wilen
Spinal motor neuron loss occurs through a p53-and-p21-independent mechanism in the Smn, Emily J Reedich, Martin Kalski, Nicholas Armijo, Gregory A. Cox, and Christine J DiDonato
KG-COVID-19: A Framework to Produce Customized Knowledge Graphs for COVID-19 Response., Justin T Reese, Deepak Unni, Tiffany J Callahan, Luca Cappelletti, Vida Ravanmehr, Seth Carbon, Kent A Shefchek, Benjamin M Good, James P Balhoff, Tommaso Fontana, Hannah Blau, Nicolas Matentzoglu, Nomi L Harris, Monica C Munoz-Torres, Melissa A Haendel, Peter N Robinson, Marcin P Joachimiak, and Christopher J Mungall
GA4GH: International policies and standards for data sharing across genomic research and healthcare., Heidi L Rehm, Angela J H Page, Lindsay Smith, Jeremy B Adams, Gil Alterovitz, Lawrence J Babb, Maxmillian P Barkley, Michael Baudis, Michael J S Beauvais, Tim Beck, Jacques S Beckmann, Sergi Beltran, David Bernick, Alexander Bernier, James K Bonfield, Tiffany F Boughtwood, Guillaume Bourque, Sarion R Bowers, Anthony J Brookes, Michael Brudno, Matthew H Brush, David Bujold, Tony Burdett, Orion J Buske, Moran N Cabili, Daniel L Cameron, Robert J Carroll, Esmeralda Casas-Silva, Debyani Chakravarty, Bimal P Chaudhari, Shu Hui Chen, J Michael Cherry, Justina Chung, Melissa Cline, Hayley L Clissold, Robert M Cook-Deegan, Mélanie Courtot, Fiona Cunningham, Miro Cupak, Robert M Davies, Danielle Denisko, Megan J Doerr, Lena I Dolman, Edward S Dove, L Jonathan Dursi, Stephanie O M Dyke, James A Eddy, Karen Eilbeck, Kyle P Ellrott, Susan Fairley, Khalid A Fakhro, Helen V Firth, Michael S Fitzsimons, Marc Fiume, Paul Flicek, Ian M Fore, Mallory A Freeberg, Robert R Freimuth, Lauren A Fromont, Jonathan Fuerth, Clara L Gaff, Weiniu Gan, Elena M Ghanaim, David Glazer, Robert C Green, Malachi Griffith, Obi L Griffith, Robert L Grossman, Tudor Groza, Jaime M Guidry Auvil, Roderic Guigó, Dipayan Gupta, Melissa A Haendel, Ada Hamosh, David P Hansen, Reece K Hart, Dean Mitchell Hartley, David Haussler, Rachele M Hendricks-Sturrup, Calvin W L Ho, Ashley E Hobb, Michael M Hoffman, Oliver M Hofmann, Petr Holub, Jacob Shujui Hsu, Jean-Pierre Hubaux, Sarah E Hunt, Ammar Husami, Julius O Jacobsen, Saumya S Jamuar, Elizabeth L Janes, Francis Jeanson, Aina Jené, Amber L Johns, Yann Joly, Steven J M Jones, Alexander Kanitz, Kazuto Kato, Thomas M Keane, Kristina Kekesi-Lafrance, Jerome Kelleher, Giselle Kerry, Seik-Soon Khor, Bartha M Knoppers, Melissa A Konopko, Kenjiro Kosaki, Martin Kuba, Jonathan Lawson, Rasko Leinonen, Stephanie Li, Michael F Lin, Mikael Linden, Xianglin Liu, Isuru Udara Liyanage, Javier Lopez, Anneke M Lucassen, Michael Lukowski, Alice L Mann, John Marshall, Michele Mattioni, Alejandro Metke-Jimenez, Anna Middleton, Richard J Milne, Fruzsina Molnár-Gábor, Nicola Mulder, Monica C Munoz-Torres, Rishi Nag, Hidewaki Nakagawa, Jamal Nasir, Arcadi Navarro, Tristan H Nelson, Ania Niewielska, Amy Nisselle, Jeffrey Niu, Tommi H Nyrönen, Brian D O'Connor, Sabine Oesterle, Soichi Ogishima, Vivian Ota Wang, Laura A D Paglione, Emilio Palumbo, Helen E Parkinson, Anthony A Philippakis, Angel D Pizarro, Andreas Prlic, Jordi Rambla, Augusto Rendon, Renee A Rider, Peter N Robinson, Kurt W Rodarmer, Laura Lyman Rodriguez, Alan F Rubin, Manuel Rueda, Gregory A Rushton, Rosalyn S Ryan, Gary I Saunders, Helen Schuilenburg, Torsten Schwede, Serena Scollen, Alexander Senf, Nathan C Sheffield, Neerjah Skantharajah, Albert V Smith, Heidi J Sofia, Dylan Spalding, Amanda B Spurdle, Zornitza Stark, Lincoln D Stein, Makoto Suematsu, Patrick Tan, Jonathan A Tedds, Alastair A Thomson, Adrian Thorogood, Timothy L Tickle, Katsushi Tokunaga, Juha Törnroos, David Torrents, Sean Upchurch, Alfonso Valencia, Roman Valls Guimera, Jessica Vamathevan, Susheel Varma, Danya F Vears, Coby Viner, Craig Voisin, Alex H Wagner, Susan E Wallace, Brian P Walsh, Marc S Williams, Eva C Winkler, Barbara J Wold, Grant M Wood, J Patrick Woolley, Chisato Yamasaki, Andrew D Yates, Christina K Yung, Lyndon J Zass, Ksenia Zaytseva, Junjun Zhang, Peter Goodhand, Kathryn North, and Ewan Birney
Direct characterization of cis-regulatory elements and functional dissection of complex genetic associations using HCR-FlowFISH., Steven K Reilly, Sager J Gosai, Alan Gutierrez, Ava Mackay-Smith, Jacob C Ulirsch, Masahiro Kanai, Kousuke Mouri, Daniel Berenzy, Susan Kales, Gina M Butler, Adrianne Gladden-Young, Redwan M Bhuiyan, Michael L. Stitzel, Hilary K Finucane, Pardis C Sabeti, and Ryan Tewhey
Interpretation of psychiatric genome-wide association studies with multispecies heterogeneous functional genomic data integration., Timothy Reynolds, Emma C Johnson, Spencer B Huggett, Jason A. Bubier, Rohan H C Palmer, Arpana Agrawal, Erich J Baker, and Elissa J Chesler
Multi-Polygenic Analysis of Nicotine Dependence in Individuals of European Ancestry., Victoria A Risner, Chelsie E Benca-Bachman, Lauren Bertin, Alicia K Smith, Jaakko Kaprio, John E McGeary, Elissa J Chesler, Valerie S Knopik, Naomi P Friedman, and Rohan H C Palmer
A CRISPR-Cas9-engineered mouse model for GPI-anchor deficiency mirrors human phenotypes and exhibits hippocampal synaptic dysfunctions., Miguel Rodríguez de Los Santos, Marion Rivalan, Friederike S David, Alexander Stumpf, Julika Pitsch, Despina Tsortouktzidis, Laura Moreno Velasquez, Anne Voigt, Karl Schilling, Daniele Mattei, Melissa Long, Guido Vogt, Alexej Knaus, Björn Fischer-Zirnsak, Lars Wittler, Bernd Timmermann, Peter N Robinson, Denise Horn, Stefan Mundlos, Uwe Kornak, Albert J Becker, Dietmar Schmitz, York Winter, and Peter M Krawitz
Hair follicle dystrophy in a litter of domestic cats resembling lanceolate hair mutant mice., Ana Rostaher, Sonya Bettenay, Lisa Specht, Kathleen A Silva, Lesley S Bechtold, Jiang Chen, Monir Majzoub, Ralf S Mueller, and John P Sundberg
Gene-by-environment modulation of lifespan and weight gain in the murine BXD family., Suheeta Roy, Maroun Bou Sleiman, Pooja Jha, Jesse F Ingels, Casey J Chapman, Melinda S McCarty, Jesse D Ziebarth, Michael Hook, Anna Sun, Wenyuan Zhao, Jinsong Huang, Sarah M Neuner, Lynda A Wilmott, Thomas M Shapaker, Arthur G Centeno, David G Ashbrook, Megan K Mulligan, Catherine Kaczorowski, Liza Makowski, Yan Cui, Robert W Read, Richard A Miller, Khyobeni Mozhui, Evan G Williams, Saunak Sen, Lu Lu, Johan Auwerx, and Robert W Williams
Tet2 Controls the Responses of β cells to Inflammation in Autoimmune Diabetes., Jinxiu Rui, Songyan Deng, Ana Luisa Perdigoto, Gerald Ponath, Romy Kursawe, Nathan Lawlor, Tomokazu Sumida, Maya Levine-Ritterman, Michael L. Stitzel, David Pitt, Jun Lu, and Kevan C Herold
The Gut Microbiome and Substance Use Disorder., Jordan T Russell, Yanjiao Zhou, George M. Weinstock, and Jason A. Bubier
The NIH Somatic Cell Genome Editing program., Krishanu Saha, Erik J Sontheimer, P J Brooks, Melinda R Dwinell, Charles A Gersbach, David R Liu, Stephen A. Murray, Shengdar Q Tsai, Ross C Wilson, Daniel G Anderson, Aravind Asokan, Jillian F Banfield, Krystof S Bankiewicz, Gang Bao, Jeff W M Bulte, Nenad Bursac, Jarryd M Campbell, Daniel F Carlson, Elliot L Chaikof, Zheng-Yi Chen, R Holland Cheng, Karl J Clark, David T Curiel, James E Dahlman, Benjamin E Deverman, Mary E Dickinson, Jennifer A Doudna, Stephen C Ekker, Marina E Emborg, Guoping Feng, Benjamin S Freedman, David M Gamm, Guangping Gao, Ionita C Ghiran, Peter M Glazer, Shaoqin Gong, Jason D Heaney, Jon D Hennebold, John T Hinson, Anastasia Khvorova, Samira Kiani, William R Lagor, Kit S Lam, Kam W Leong, Jon E Levine, Jennifer A Lewis, Cathleen Lutz, Danith H Ly, Samantha Maragh, Paul B McCray, Todd C McDevitt, Oleg Mirochnitchenko, Ryuji Morizane, Niren Murthy, Randall S Prather, John A Ronald, Subhojit Roy, Sushmita Roy, Venkata Sabbisetti, W Mark Saltzman, Philip J Santangelo, David J Segal, Mary Shimoyama, Melissa C Skala, Alice F Tarantal, John C Tilton, George A Truskey, Moriel Vandsburger, Jonathan K Watts, Kevin D Wells, Scot A Wolfe, Qiaobing Xu, Wen Xue, Guohua Yi, and Jiangbing Zhou
Sex-specific phenotypic effects and evolutionary history of an ancient polymorphic deletion of the human growth hormone receptor., Marie Saitou, Skyler Resendez, Apoorva J Pradhan, Fuguo Wu, Natasha C Lie, Nancy J Hall, Qihui Zhu, Laura G Reinholdt, Yoko Satta, Leo Speidel, Shigeki Nakagome, Neil A Hanchard, Gary Churchill, Charles Lee, G Ekin Atilla-Gokcumen, Xiuqian Mu, and Omer Gokcumen
Identification of cell-surface glycans that mediate motility-dependent binding and internalization of Pseudomonas aeruginosa by phagocytes., Hector Sanchez, Daniel Hopkins, Sally Demirdjian, Cecilia Gutierrez, George A O'Toole, Sriram Neelamegham, and Brent Berwin
Employees' Views and Ethical, Legal, and Social Implications Assessment of Voluntary Workplace Genomic Testing, Kunal Sanghavi, W Gregory Feero, Debra JH Mathews, Anya ER Prince, Lori Lyn Price, Edison Liu, Kyle Brothers, J Scott Roberts, and Charles Lee
Abdominal Computed Tomography Imaging Findings in Hospitalized COVID-19 Patients: A Year-Long Experience and Associations Revealed by Explainable Artificial Intelligence., Alice Scarabelli, Massimo Zilocchi, Elena Casiraghi, Pierangelo Fasani, Guido Giovanni Plensich, Andrea Alessandro Esposito, Elvira Stellato, Alessandro Petrini, Justin Reese, Peter N Robinson, Giorgio Valentini, and Gianpaolo Carrafiello
Solving unsolved rare neurological diseases-a Solve-RD viewpoint., Rebecca Schüle, Dagmar Timmann, Corrie E Erasmus, Jennifer Reichbauer, Melanie Wayand, Bart van de Warrenburg, Ludger Schöls, Carlo Wilke, Andrea Bevot, Stephan Zuchner, Sergi Beltran, Steven Laurie, Leslie Matalonga, Holm Graessner, Matthis Synofzik, Solve-RD Consortium, and Peter N Robinson
Challenges to making an egg., Richard M Schultz and John J. Eppig
Allopregnanolone Improves Locomotor Activity and Arousal in the Aged CGG Knock-in Mouse Model of Fragile X-Associated Tremor/Ataxia Syndrome., Jared J Schwartzer, Dolores Garcia-Arocena, Amanda Jamal, Ali Izadi, Rob Willemsen, and Robert F Berman
Targeting metabolism to reverse T-cell exhaustion in chronic viral infections., John D Sears, Kevin J Waldron, Jian Wei, and Chih-Hao (Lucas) Chang
Micronuclei in Kif18a mutant mice form stable micronuclear envelopes and do not promote tumorigenesis., Leslie A Sepaniac, Whitney Martin, Louise A. Dionne, Timothy M Stearns, Laura G Reinholdt, and Jason Stumpff
Preclinical evaluation of cancer immune therapy using patient-derived tumor antigen-specific T cells in a novel xenograft platform., Gautam N Shenoy, Christopher J Greene, Maulasri Bhatta, Miren L Baroja, Jenni L Loyall, Sathy V Balu-Iyer, Raymond J Kelleher, Beatriz M Carreno, Gerald P Linette, Leonard D. Shultz, and Richard B Bankert
Targeting eIF4A-Dependent Translation of KRAS Signaling Molecules., Kamini Singh, Jianan Lin, Nicolas Lecomte, Prathibha Mohan, Askan Gokce, Viraj R Sanghvi, Man Jiang, Olivera Grbovic-Huezo, Antonija Burčul, Stefan G Stark, Paul B Romesser, Qing Chang, Jerry P Melchor, Rachel K Beyer, Mark Duggan, Yoshiyuki Fukase, Guangli Yang, Ouathek Ouerfelli, Agnes Viale, Elisa de Stanchina, Andrew W Stamford, Peter T Meinke, Gunnar Rätsch, Steven D Leach, Zhengqing Ouyang, and Hans-Guido Wendel
100,000 Genomes Pilot on Rare-Disease Diagnosis in Health Care - Preliminary Report., Damian Smedley, Katherine R Smith, Antonio Martin, Ellen A Thomas, Ellen M McDonagh, Valentina Cipriani, Jamie M Ellingford, Gavin Arno, Arianna Tucci, Jana Vandrovcova, Georgia Chan, Hywel J Williams, Thiloka Ratnaike, Wei Wei, Kathleen Stirrups, Kristina Ibanez, Loukas Moutsianas, Matthias Wielscher, Anna Need, Michael R Barnes, Letizia Vestito, James Buchanan, Sarah Wordsworth, Sofie Ashford, Karola Rehmström, Emily Li, Gavin Fuller, Philip Twiss, Olivera Spasic-Boskovic, Sally Halsall, R Andres Floto, Kenneth Poole, Annette Wagner, Sarju G Mehta, Mark Gurnell, Nigel Burrows, Roger James, Christopher Penkett, Eleanor Dewhurst, Stefan Gräf, Rutendo Mapeta, Mary Kasanicki, Andrea Haworth, Helen Savage, Melanie Babcock, Martin G Reese, Mark Bale, Emma Baple, Christopher Boustred, Helen Brittain, Anna de Burca, Marta Bleda, Andrew Devereau, Dina Halai, Eik Haraldsdottir, Zerin Hyder, Dalia Kasperaviciute, Christine Patch, Dimitris Polychronopoulos, Angela Matchan, Razvan Sultana, Mina Ryten, Ana L T Tavares, Carolyn Tregidgo, Clare Turnbull, Matthew Welland, Suzanne Wood, Catherine Snow, Eleanor Williams, Sarah Leigh, Rebecca E Foulger, Louise C Daugherty, Olivia Niblock, Ivone U S Leong, Caroline F Wright, Jim Davies, Charles Crichton, James Welch, Kerrie Woods, Lara Abulhoul, Paul Aurora, Detlef Bockenhauer, Alexander Broomfield, Maureen A Cleary, Tanya Lam, Mehul Dattani, Emma Footitt, Vijeya Ganesan, Stephanie Grunewald, Sandrine Compeyrot-Lacassagne, Francesco Muntoni, Clarissa Pilkington, Rosaline Quinlivan, Nikhil Thapar, Colin Wallis, Lucy R Wedderburn, Austen Worth, Teofila Bueser, Cecilia Compton, Charu Deshpande, Hiva Fassihi, Eshika Haque, Louise Izatt, Dragana Josifova, Shehla Mohammed, Leema Robert, Sarah Rose, Deborah Ruddy, Robert Sarkany, Genevieve Say, Adam C Shaw, Agata Wolejko, Bishoy Habib, Gavin Burns, Sarah Hunter, Russell J Grocock, Sean J Humphray, Peter N Robinson, Melissa Haendel, Michael A Simpson, Siddharth Banka, Jill Clayton-Smith, Sofia Douzgou, Georgina Hall, Huw B Thomas, Raymond T O'Keefe, Michel Michaelides, Anthony T Moore, Sam Malka, Nikolas Pontikos, Andrew C Browning, Volker Straub, Gráinne S Gorman, Rita Horvath, Richard Quinton, Andrew M Schaefer, Patrick Yu-Wai-Man, Doug M Turnbull, Robert McFarland, Robert W Taylor, Emer O'Connor, Janice Yip, Katrina Newland, Huw R Morris, James Polke, Nicholas W Wood, Carolyn Campbell, Carme Camps, Kate Gibson, Nils Koelling, Tracy Lester, Andrea H Németh, Claire Palles, Smita Patel, Noemi B A Roy, Arjune Sen, John Taylor, Pilar Cacheiro, Julius O Jacobsen, Eleanor G Seaby, Val Davison, Lyn Chitty, Angela Douglas, Kikkeri Naresh, Dom McMullan, Sian Ellard, I Karen Temple, Andrew D Mumford, Gill Wilson, Phil Beales, Maria Bitner-Glindzicz, Graeme Black, John R Bradley, Paul Brennan, John Burn, Patrick F Chinnery, Perry Elliott, Frances Flinter, Henry Houlden, Melita Irving, William Newman, Shamima Rahman, John A Sayer, Jenny C Taylor, Andrew R Webster, Andrew O M Wilkie, Willem H Ouwehand, F Lucy Raymond, John Chisholm, Sue Hill, David Bentley, Richard H Scott, Tom Fowler, Augusto Rendon, and Mark Caulfield
The integrated stress response contributes to tRNA synthetase-associated peripheral neuropathy., Emily L Spaulding, Timothy J Hines, Preeti Bais, Abigail LD Tadenev, Robert Schneider, Dakota Jewett, B Pattavina, S L Pratt, K H Morelli, M G Stum, David P. Hill, C Gobet, M Pipis, M M Reilly, M J Jennings, R Horvath, Y Bai, M E Shy, B Alvarez-Castelao, E M Schuman, Laurent P. Bogdanik, E Storkebaum, and Robert W. Burgess
Cardiac cellularity is dependent upon biological sex and is regulated by gonadal hormones., Galen T Squiers, Michael A McLellan, Alexei Ilinykh, Jane Branca, Nadia Rosenthal, and Alexander R Pinto
A systems approach using Diversity Outbred mice distinguishes the cardiovascular effects and genetics of circulating GDF11 from those of its homolog, myostatin., Abigail E Starcher, Kristen Peissig, James B Stanton, Gary A Churchill, Dunpeng Cai, Joshua T Maxwell, Arthur Grider, Kim Love, Shi-You Chen, Amanda E Coleman, Emma Strauss, and Robert Pazdro
Genetic analysis of Pycr1 and Pycr2 in mice., Morgane G Stum, Abby Tadenev, Kevin L. Seburn, Kathy E Miers, Pak P Poon, Christopher R McMaster, Carolyn Robinson, Coleen C. Kane, Kathleen A Silva, Paul F Cliften, John P Sundberg, Laura G Reinholdt, Simon W M John, and Robert W. Burgess
Comprehensive characterization of 536 patient-derived xenograft models prioritizes candidatesfor targeted treatment., Hua Sun, Song Cao, R Jay Mashl, Chia-Kuei Mo, Simone Zaccaria, Michael C Wendl, Sherri R Davies, Matthew H Bailey, Tina M Primeau, Jeremy Hoog, Jacqueline L Mudd, Dennis A Dean, Rajesh Patidar, Li Chen, Matthew A Wyczalkowski, Reyka G Jayasinghe, Fernanda Martins Rodrigues, Nadezhda V Terekhanova, Yize Li, Kian-Huat Lim, Andrea Wang-Gillam, Brian A Van Tine, Cynthia X Ma, Rebecca Aft, Katherine C Fuh, Julie K Schwarz, Jose P Zevallos, Sidharth V Puram, John F Dipersio, NCI PDXNet Consortium, Brandi Davis-Dusenbery, Matthew J Ellis, Michael T Lewis, Michael A Davies, Meenhard Herlyn, Bingliang Fang, Jack A Roth, Alana L Welm, Bryan E Welm, Funda Meric-Bernstam, Feng Chen, Ryan C Fields, Shunqiang Li, Ramaswamy Govindan, James H Doroshow, Jeffrey A Moscow, Yvonne A Evrard, Jeffrey Chuang, Benjamin J Raphael, Li Ding, Carol J Bult, and Peter N Robinson
Dietary Vitamin A Impacts Refractory Telogen., Liye Suo, Christine VanBuren, Eylul Damla Hovland, Natalia Y Kedishvili, John P Sundberg, and Helen B Everts
Role of MicroRNA in Inflammatory Bowel Disease: Clinical Evidence and the Development of Preclinical Animal Models., Kanika Suri, Jason A. Bubier, Michael V. Wiles, Leonard D. Shultz, Mansoor M Amiji, and Vishnu Hosur
Mouse Genetic Reference Populations: Cellular Platforms for Integrative Systems Genetics., Emily Swanzey, Callan O'Connor, and Laura G Reinholdt
Disease Progression in Children with Perinatal HIV Correlates with Increased PD-1+ CD8 T Cells that Coexpress Multiple Immune Checkpoints., Janki Tailor, Julia Foldi, Matthew Generoso, Bret McCarty, Aparna Alankar, Max Kilberg, Mussa Mwamzuka, Fatma Marshed, Aabid Ahmed, Mengling Liu, William Borkowsky, Derya Unutmaz, and Alka Khaitan
Proteomic and transcriptomic profiling reveal different aspects of aging in the kidney., Yuka Takemon, Joel M Chick, Isabela Gerdes Gyuricza, Daniel A Skelly, Olivier Devuyst, Steven P Gygi, Gary Churchill, and Ron Korstanje
Uncovering Modifier Genes of X-Linked Alport Syndrome Using a Novel Multiparent Mouse Model., Yuka Takemon, Valerie Wright, Bernard Davenport, Daniel M. Gatti, Susan Sheehan, Kelsey Letson, Holly S Savage, Rachel Lennon, and Ron Korstanje
Capsule carbohydrate structure determines virulence in Acinetobacter baumannii., Yuli Talyansky, Travis B Nielsen, Jun Yan, Ulrike Carlino-Macdonald, Gisela Di Venanzio, Somnath Chakravorty, Amber Ulhaq, Mario F Feldman, Thomas A Russo, Evgeny Vinogradov, Brian Luna, Meredith S Wright, Mark D Adams, and Brad Spellberg
A Reversal in Hair Cell Orientation Organizes Both the Auditory and Vestibular Organs., Basile Tarchini
Reprogramming of bivalent chromatin states in NRAS mutant melanoma suggests PRC2 inhibition as a therapeutic strategy., Christopher J Terranova, Ming Tang, Mayinuer Maitituoheti, Ayush T Raman, Archit K Ghosh, Jonathan Schulz, Samirkumar B Amin, Elias Orouji, Katarzyna Tomczak, Sharmistha Sarkar, Junna Oba, Caitlin Creasy, Chang-Jiun Wu, Samia Khan, Rossana Lazcano, Khalida Wani, Anand Singh, Praveen Barrodia, Dongyu Zhao, Kaifu Chen, Lauren E Haydu, Wei-Lien Wang, Alexander J Lazar, Scott E Woodman, Chantale Bernatchez, and Kunal Rai
Defects in translation-dependent quality control pathways lead to convergent molecular and neurodevelopmental pathology., Markus Terrey, Scott I Adamson, Jeffrey H Chuang, and Susan L Ackerman
DTi2Vec: Drug-target interaction prediction using network embedding and ensemble learning., Maha A Thafar, Rawan S Olayan, Somayah Albaradei, Vladimir B Bajic, Takashi Gojobori, Magbubah Essack, and Xin Gao
AMULET: a novel read count-based method for effective multiplet detection from single nucleus ATAC-seq data., Asa Thibodeau, Alper Eroglu, Christopher S McGinnis, Nathan Lawlor, Djamel Nehar-Belaid, Romy Kursawe, Radu Marches, Daniel N Conrad, George A Kuchel, Zev J Gartner, Jacques Banchereau, Michael L. Stitzel, A Ercument Cicek, and Duygu Ucar
CoRE-ATAC: A deep learning model for the functional classification of regulatory elements from single cell and bulk ATAC-seq data., Asa Thibodeau, Shubham Khetan, Alper Eroglu, Ryan Tewhey, Michael L. Stitzel, and Duygu Ucar
Convergence of mammalian RQC and C-end rule proteolytic pathways via alanine tailing., Anna Thrun, Aitor Garzia, Yu Kigoshi-Tansho, Pratik R Patil, Charles S Umbaugh, Teresa Dallinger, Jia Liu, Sylvia Kreger, Annarita Patrizi, Gregory A. Cox, Thomas Tuschl, and Claudio A P Joazeiro
CACHD1-deficient mice exhibit hearing and balance deficits associated with a disruption of calcium homeostasis in the inner ear., Cong Tian, Kenneth R. Johnson, Jaclynn M Lett, Robert Voss, Alec N Salt, Jared J Hartsock, Peter S Steyger, and Kevin K Ohlemiller
EWSR1 affects PRDM9-dependent histone 3 methylation and provides a link between recombination hotspots and the chromosome axis protein REC8., Hui Tian, Timothy Billings, and Petko M. Petkov
Mouse EWSR1 is crucial for spermatid post-meiotic transcription and spermiogenesis., Hui Tian and Petko M. Petkov
Genetic background modifies vulnerability to glaucoma-related phenotypes in, Nicholas G Tolman, Revathi Balasubramanian, Danilo G Macalinao, Alison L Kearney, Katharine H MacNicoll, Christa L Montgomery, Wilhelmine N de Vries, Ian J Jackson, Sally H Cross, Krishnakumar Kizhatil, K Saidas Nair, and Simon W M John
Single cell sequencing reveals endothelial plasticity with transient mesenchymal activation after myocardial infarction., Lukas S Tombor, David John, Simone F Glaser, Guillermo Luxán, Elvira Forte, Milena B Furtado, Nadia Rosenthal, Nina Baumgarten, Marcel H Schulz, Janina Wittig, Eva-Maria Rogg, Yosif Manavski, Ariane Fischer, Marion Muhly-Reinholz, Kathrin Klee, Mario Looso, Carmen Selignow, Till Acker, Sofia-Iris Bibli, Ingrid Fleming, Ralph Patrick, Richard P Harvey, Wesley T Abplanalp, and Stefanie Dimmeler
Nicotinamide provides neuroprotection in glaucoma by protecting against mitochondrial and metabolic dysfunction., James R Tribble, Amin Otmani, Shanshan Sun, Sevannah A Ellis, Gloria Cimaglia, Rupali Vohra, Melissa Jöe, Emma Lardner, Abinaya P Venkataraman, Alberto Domínguez-Vicent, Eirini Kokkali, Seungsoo Rho, Gauti Jóhannesson, Robert W. Burgess, Peter G Fuerst, Rune Brautaset, Miriam Kolko, James E Morgan, Jonathan G Crowston, Marcela Votruba, and Pete A Williams
Genetic basis for an evolutionary shift from ancestral preaxial to postaxial limb polarity in non-urodele vertebrates., Anna Trofka, Bau-Lin Huang, Jianjian Zhu, William F Heinz, Valentin Magidson, Yuki Shibata, Yun-Bo Shi, Basile Tarchini, H Scott Stadler, Mirindi Kabangu, Nour W Al Haj Baddar, S Randal Voss, and Susan Mackem
Innate immune pathways and inflammation in hematopoietic aging, clonal hematopoiesis, and MDS., Jennifer J. Trowbridge and Daniel T Starczynowski
Effects of kinship correction on inflation of genetic interaction statistics in commonly used mouse populations., Anna L. Tyler, Baha El Kassaby, Georgi Kolishovski, Jake Emerson, Ann E Wells, J Matthew Mahoney, and Gregory W. Carter
The Combined Analysis of Pleiotropy and Epistasis (CAPE)., Anna L. Tyler, Jake Emerson, Baha El Kassaby, Ann E Wells, Vivek M. Philip, and Gregory W. Carter
A Transcription Start Site Map in Human Pancreatic Islets Reveals Functional Regulatory Signatures., Arushi Varshney, Yasuhiro Kyono, Venkateswaran Ramamoorthi Elangovan, Collin Wang, Michael R Erdos, Narisu Narisu, Ricardo D'Oliveira Albanus, Peter Orchard, Michael L. Stitzel, Francis S Collins, Jacob O Kitzman, and Stephen C J Parker
Enhanced tyrosine hydroxylase activity induces oxidative stress, causes accumulation of autotoxic catecholamine metabolites, and augments amphetamine effects in vivo., Laura M Vecchio, Patricia Sullivan, Amy R Dunn, Marie Kristel Bermejo, Rong Fu, Shababa T Masoud, Emil Gregersen, Nikhil M Urs, Reza Nazari, Poul Henning Jensen, Amy Ramsey, David S Goldstein, Gary W Miller, and Ali Salahpour
Spatial concordance of DNA methylation classification in diffuse glioma., Niels Verburg, Floris P Barthel, Kevin J Anderson, Kevin C Johnson, Thomas Koopman, Maqsood M Yaqub, Otto S Hoekstra, Adriaan A Lammertsma, Frederik Barkhof, Petra J W Pouwels, Jaap C Reijneveld, Annemieke J M Rozemuller, Jeroen A M Beliën, Ronald Boellaard, Michael D Taylor, Sunit Das, Joseph F Costello, William Peter Vandertop, Pieter Wesseling, Philip C de Witt Hamer, and Roel G W Verhaak
MEK inhibition reprograms CD8 + T lymphocytes into memory stem cells with potent antitumor effects, Vivek Verma, Nazli Jafarzadeh, Shannon Boi, Subhadip Kundu, Zhinuo Jiang, Yiping Fan, Jose Lopez, Rahul Nandre, Peng Zeng, Fatmah Alolaqi, Shamim Ahmad, Pankaj Gaur, Simon T Barry, Viia E Valge-Archer, Paul D Smith, Jacques Banchereau, Mikayel Mkrtichyan, Benjamin Youngblood, Paulo C Rodriguez, Seema Gupta, and Samir N Khleif
Translational animal models for Alzheimer's disease: An Alzheimer's Association Business Consortium Think Tank., Michael P Vitek, Joseph A Araujo, Michael Fossel, Barry D Greenberg, Gareth R Howell, Stacey J Sukoff Rizzo, Nicholas T Seyfried, Andrea J Tenner, Paul R Territo, Manfred Windisch, Lisa J Bain, April Ross, Maria C Carrillo, Bruce T Lamb, and Rebecca M Edelmayer
PD-1 Blockade Aggravates Epstein-Barr Virus + Post-Transplant Lymphoproliferative Disorder in Humanized Mice Resulting in Central Nervous System Involvement and CD4 + T Cell Dysregulations., Valery Volk, Sebastian J Theobald, Simon Danisch, Sahamoddin Khailaie, Maja Kalbarczyk, Andreas Schneider, Julia Bialek-Waldmann, Nicole Krönke, Yun Deng, Britta Eiz-Vesper, Anna Christina Dragon, Constantin von Kaisenberg, Stefan Lienenklaus, Andre Bleich, James Keck, Michael Meyer-Hermann, Frank Klawonn, Wolfgang Hammerschmidt, Henri-Jacques Delecluse, Christian Münz, Friedrich Feuerhake, and Renata Stripecke
In situ Chromatin Interaction Analysis Using Paired-End Tag Sequencing., Ping Wang, Yuliang Feng, Kun Zhu, Haoxi Chai, Ya-Ting Chang, Xiaofei Yang, Xiyuan Liu, Chen Shen, Eva Gega, Byoungkoo Lee, Minji Kim, Xiaoan Ruan, and Yijun Ruan
A novel CD4+ CTL subtype characterized by chemotaxis and inflammation is involved in the pathogenesis of Graves' orbitopathy., Yue Wang, Ziyi Chen, Tingjie Wang, Hui Guo, Yufeng Liu, Ningxin Dang, Shiqian Hu, Liping Wu, Chengsheng Zhang, Kai Ye, and Bingyin Shi
Overlapping roles for PLK1 and Aurora A during meiotic centrosome biogenesis in mouse spermatocytes., Stephen R Wellard, Yujiao Zhang, Chris Shults, Xueqi Zhao, Matthew Mckay, Stephen A. Murray, and Philip W Jordan
Multiwalled carbon nanotubes co-delivering sorafenib and epidermal growth factor receptor siRNA enhanced tumor-suppressing effect on liver cancer., Zhili Wen, Yuliang Feng, Youwen Hu, Lingyan Lian, Hongyan Huang, Li Guo, Shanwen Chen, Qian Yang, Moran Zhang, Lijun Wan, Kedong Xu, Degejirifu, and Xiaohua Yan
Similar risk of hepatocellular carcinoma during long-term entecavir or tenofovir therapy in Caucasian patients with chronic hepatitis B., Zhili Wen, Yuliang Feng, and Xiaohua Yan
Atypical is the new norm, for B cells and the rest of us., Adam Williams and Stephanie C Eisenbarth
Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts., Xing Yi Woo, Jessica Giordano, Anuj Srivastava, Zi-Ming Zhao, Michael W Lloyd, Roebi de Bruijn, Yun-Suhk Suh, Rajesh Patidar, Li Chen, Sandra Scherer, Matthew H Bailey, Chieh-Hsiang Yang, Emilio Cortes-Sanchez, Yuanxin Xi, Jing Wang, Jayamanna Wickramasinghe, Andrew V Kossenkov, Vito W Rebecca, Hua Sun, R Jay Mashl, Sherri R Davies, Ryan Jeon, Christian Frech, Jelena Randjelovic, Jacqueline Rosains, Francesco Galimi, Andrea Bertotti, Adam Lafferty, Alice C O'Farrell, Elodie Modave, Diether Lambrechts, Petra Ter Brugge, Violeta Serra, Elisabetta Marangoni, Rania El Botty, Hyunsoo Kim, Jong-Il Kim, Han-Kwang Yang, Charles Lee, Dennis A Dean, Brandi Davis-Dusenbery, Yvonne A Evrard, James H Doroshow, Alana L Welm, Bryan E Welm, Michael T Lewis, Bingliang Fang, Jack A Roth, Funda Meric-Bernstam, Meenhard Herlyn, Michael A Davies, Li Ding, Shunqiang Li, Ramaswamy Govindan, Claudio Isella, Jeffrey A Moscow, Livio Trusolino, Annette T Byrne, Jos Jonkers, Carol J Bult, Enzo Medico, Jeffrey Chuang, PDXNET Consortium, and EurOPDX Consortium
Victor McKusick and his short course., Charles Wray, Gregory A. Cox, and David Valle
A new graph-based clustering method with application to single-cell RNA-seq data from human pancreatic islets., Hao Wu, Disheng Mao, Yuping Zhang, Zhiyi Chi, Michael L. Stitzel, and Zhengqing Ouyang
Actinomycin D Targets NPM1c-Primed Mitochondria to Restore PML-Driven Senescence in AML Therapy., Hsin-Chieh Wu, Domitille Rérolle, Caroline Berthier, Rita Hleihel, Takashi Sakamoto, Samuel Quentin, Shirine Benhenda, Claudia Morganti, Chengchen Wu, Lidio Conte, Sylvie Rimsky, Marie Sebert, Emmanuelle Clappier, Sylvie Souquere, Stéphanie Gachet, Jean Soulier, Sylvère Durand, Jennifer J. Trowbridge, Paule Bénit, Pierre Rustin, Hiba El Hajj, Emmanuel Raffoux, Lionel Ades, Raphael Itzykson, Hervé Dombret, Pierre Fenaux, Olivier Espeli, Guido Kroemer, Lorenzo Brunetti, Tak W Mak, Valérie Lallemand-Breitenbach, Ali Bazarbachi, Brunangelo Falini, Keisuke Ito, Maria Paola Martelli, and Hugues de Thé
RUNX1-mediated alphaherpesvirus-host trans-species chromatin interaction promotes viral transcription., Ke Xiao, Dan Xiong, Gong Chen, Jinsong Yu, Yue Li, Kening Chen, Lu Zhang, Yangyang Xu, Qian Xu, Xi Huang, Anran Gao, Kai Cao, Keji Yan, Jinxia Dai, Xueying Hu, Yijun Ruan, Zhenfang Fu, Guoliang Li, and Gang Cao
Natural genetic variation determines microglia heterogeneity in wild-derived mouse models of Alzheimer's disease., Hongtian Stanley Yang, Kristen D. Onos, Kwangbom Choi, Kelly J Keezer, Daniel A Skelly, Gregory W. Carter, and Gareth R Howell
A missense mutation in Pitx2 leads to early-onset glaucoma via NRF2-YAP1 axis., Yeming Yang, Xiao Li, Jieping Wang, Junkai Tan, Bernie Fitzmaurice, Patsy M. Nishina, Kuanxiang Sun, Wanli Tian, Wenjing Liu, Xuyang Liu, Bo Chang, and Xianjun Zhu
Decline in IGF1 in the bone marrow microenvironment initiates hematopoietic stem cell aging., Kira Young, Elizabeth Eudy, Rebecca Bell, Matthew A Loberg, Timothy M Stearns, Devyani Sharma, Lars Velten, Simon Haas, Marie-Dominique Filippi, and Jennifer J. Trowbridge
Direct DNA crosslinking with CAP-C uncovers transcription-dependent chromatin organization at high resolution., Qiancheng You, Anthony Cheng, Xi Gu, Bryan T Harada, Miao Yu, Tong Wu, Bing Ren, Zhengqing Ouyang, and Chuan He