• Home
  • Search
  • Browse Collections
  • My Account
  • About
  • DC Network Digital Commons Network™
Skip to main content
The Mouseion at the JAXlibrary The Jackson Laboratory
  • Home
  • About
  • FAQ
  • My Account

    Content Posted in 2026

     

    2.34 - Fundamentals of in vivo sampling, Katarzyna Woźniczka, Miao Yu, Nikita Looby, and Anna Roszkowska

    PDF

    7th International Workshop on SOX Transcription Factors., Aya Uchida

    PDF

    Accessible, Realistic Genome Simulation with Selection Using stdpopsim., Graham Gower, Nathaniel S Pope, Murillo F Rodrigues, Silas Tittes, Linh N Tran, Ornob Alam, Maria Izabel A Cavassim, Peter D Fields, Benjamin C Haller, Xin Huang, Ben Jeffrey, Kevin Korfmann, Christopher C Kyriazis, Jiseon Min, Inés Rebollo, Clara T Rehmann, Scott T Small, Chris C R Smith, Georgia Tsambos, Yan Wong, Yu Zhang, Christian D Huber, Gregor Gorjanc, Aaron P Ragsdale, Ilan Gronau, Ryan N Gutenkunst, Jerome Kelleher, Kirk E Lohmueller, Daniel R Schrider, Peter L Ralph, and Andrew D Kern

    PDF

    A collaborative framework for uncovering molecular and cellular drivers of VCID: Foundations for future interventions in dementia., M Luisa Iruela-Arispe, Jason D Hinman, Andrew C Yang, Fabrice Dabertrand, Jin-Moo Lee, Gareth R Howell, and The VCID Centers without Walls Network

     

    A complete genome for the common marmoset., Prajna Hebbar, Tamara Potapova, Hailey Loucks, Karina Ray, Murillo F Rodrigues, Fedor Ryabov, Joanna Malukiewicz, DongAhn Yoo, Leonardo Gomes de Lima, Annat Haber, Sonal Kumar, Swati Banerjee, Matthew Borchers, Gage H Garcia, Joshua Gardner, Stephanie Hachem, Harrison D Heath, Seung Kwon Ha, Mira Mastoras, Brandy McNulty, Julian Menendez, Katherine M Munson, Karol Pal, JungEun Park, Simon Plösch, Christian Roos, William E Seligmann, Valery Shepelev, Catrina Spruce, Ivo Violich, Lutz Walter, Kateryna D Makova, Amantha Thathiah, Stacey J Sukoff Rizzo, Afonso C Silva, Gregory W. Carter, Karen H Miga, Evan E Eichler, Donald F Conrad, Jennifer L Gerton, Ivan A Alexandrov, and Benedict Paten

    Link

    A cross-organ single-cell analysis of hypertension., Qiongzi Qiu, Yong Liu, Hong Xue, Rajan Pandey, Jing Liu, Lishu He, Pengyuan Liu, Bhavika Therani, Vinod Kumar, Jing Huang, Shima Sadri, Maya Guenther, Kristie Usa, Michael Grzybowski, Mark A Vanden Avond, Andrew S Greene, Allen W Cowley, Sridhar Rao, Aron M Geurts, and Mingyu Liang

    Link

    A dual role for GLI3 signaling in neural crest development., Simon J Y Han, Vinit Adani, Edward Farrow, Bhaval Parmar, Ching-Fang Chang, Kim Cochran, Ronald R Horne, Paige J K Ramkissoon, Ezekiel Esteban, Kelsey H Elliott, Kevin A Peterson, Brian Gebelein, Martín I García-Castro, and Samantha A Brugmann

    Link

    Advancing biological understanding of cellular senescence with computational multiomics., Sheng Li, Paula A Agudelo Garcia, Constantin Aliferis, Michael J Becich, Jazmin Calyeca, Benjamin D Cosgrove, Jennifer Elisseeff, Negin Farzad, Elana J Fertig, Carolyn Glass, Liangcai Gu, Qianjiang Hu, Zhicheng Ji, Melanie Königshoff, Nathan K LeBrasseur, Dongmei Li, Anjun Ma, Qin Ma, Vilas Menon, Jacob T Mitchell, Ana L Mora, Sushma Nagaraj, Andrew C Nelson, Laura J Niedernhofer, Mauricio Rojas, Hash Brown Taha, Jinhua Wang, Siyuan Wang, Pei-Hsun Wu, Jichun Xie, Ming Xu, Miao Yu, Xu Zhang, Yue Zhao, Peter D Adams, Cristina Aguayo-Mazzucato, Darren J Baker, Christopher Benz, David A Bernlohr, Marta Bueno, Jin Chen, Bennett G Childs, Jeffrey Chuang, Dongjun Chung, Mythili Dileepan, Li Ding, Mingze Dong, Francesca Duncan, Archibald Enninful, William F Flynn, Ana Catarina Franco, David Furman, Vesna Garovic, Stephanie Halene, Allison B Herman, Ann V Hertzel, Kanako Iwasaki, Hyeongseon Jeon, Jeon Woong Kang, Shilpita Karmakar, James L Kirkland, Ron Korstanje, Erich Kummerfeld, Jun Hee Lee, Yang Liu, Yao Lu, Jose Lugo-Martinez, Helene Martini, Simon Melov, Nicolas Musi, João F Passos, Samuel T Peters, Irfan Rahman, Ramalakshmi Ramasamy, Alexandra N Rindone, Paul D Robbins, Paul Robson, Jhonny Rodriguez-Lopez, Lorena Rosas, Nadia Rosenthal, Marissa J Schafer, Birgit Schilling, Elizabeth L Schmidt, Kevin Schneider, Kaustav Sengupta, Jian Shu, Peter T C So, Li Sun, Tamar Tchkonia, Marcos G Teneche, Natalia Vanegas, Julia Wang, Juan Xie, Shanshan Yin, Ke Zhang, Quan Zhu, Rong Fan, and SenNet Consortium

     

    Advancing gene and base editing for cardiovascular disease: overcoming barriers in delivery, precision and safety., Tae Kyeong Kim and J Travis Hinson

    PDF

    Advancing the science of genomic learning healthcare systems., Teri A Manolio, Renee Rider, Carol J Bult, Rex L Chisholm, Patricia A Deverka, Geoffrey S Ginsburg, Eric D Green, Gail P Jarvik, George A Mensah, Jahnavi Narula, Erin M Ramos, Mary V Relling, Dan M Roden, Robb Rowley, Noura S Abul-Husn, Adam H Buchanan, Christopher G Chute, Guilherme Del Fiol, Gai Elhanan, Susanne B Haga, Rizwan Hamid, Carol R Horowitz, Peter J Hulick, Cynthia A James, Janina M Jeff, Bruce Korf, Latrice Landry, Deven McGraw, Howard L McLeod, Nancy J Mendelsohn, Travis Osterman, Casey Overby Taylor, Daryl Pritchard, Heidi L Rehm, Krystal S Tsosie, Jason L Vassy, Karriem Watson, Ken Wiley, and Marc S Williams

    PDF

    African Domestic Poultry Genetic Resources, Diversity, and Unique Features, Tadelle Dessie, Christian K. Tiambo, Liveness J. Banda, Raman Akinyanju Lawal, Sheila C. Ommeh, Timothy Gondwe, Esatu Wondmeneh, Matthew A. Adeleke, and Olivier Hanotte

    PDF

    Ageing promotes microglial accumulation of slow-degrading synaptic proteins., Ian H Guldner, Viktoria P Wagner, Patricia Moran-Losada, Sophia M Shi, Sophia W Golub, Johannes F Hevler, Kelly Chen, Barbara T Meese, Ali Ghoochani, Ernst Pulido, Hamilton Se-Hwee Oh, Yann Le Guen, Nannan Lu, Pui Shuen Wong, Ning-Sum To, Dylan Garceau, Zimin Guo, Jian Luo, Carolyn R Bertozzi, Emma Lundberg, Monther Abu-Remaileh, Michael Sasner, Andreas Keller, Andrew C Yang, Tom H Cheung, and Tony Wyss-Coray

    PDF

    Ageing promotes microglial accumulation of slow-degrading synaptic proteins., Ian H Guldner, Viktoria P Wagner, Patricia Moran-Losada, Sophia M Shi, Sophia W Golub, Johannes F Hevler, Kelly Chen, Barbara T Meese, Ali Ghoochani, Ernst Pulido, Hamilton Se-Hwee Oh, Yann Le Guen, Nannan Lu, Pui Shuen Wong, Ning-Sum To, Dylan Garceau, Zimin Guo, Jian Luo, Carolyn R Bertozzi, Emma Lundberg, Monther Abu-Remaileh, Michael Sasner, Andreas Keller, Andrew C Yang, Tom H Cheung, and Tony Wyss-Coray

    Link

    Age-related macular degeneration and cerebral amyloid angiopathy have similar pathologies from cholesterol-APOE-amyloid-β-complement mediated inflammation., Whitney Stuard Sambhariya, Catherine Bowes Rickman, Patricia A D'Amore, Giulia Corradetti, Gregory S Hageman, Gareth R Howell, Olivia J Marola, Hemali Phatnani, Nancy J Philp, Debasish Sinha, Christopher B Toomey, Faith Stone, Charles Eberhart, and James T Handa

    Link

    Age-related macular degeneration and cerebral amyloid angiopathy have similar pathologies from cholesterol-APOE-amyloid-β-complement mediated inflammation., Whitney Stuard Sambhariya, Catherine Bowes Rickman, Patricia A D'Amore, Giulia Corradetti, Gregory S Hageman, Gareth R Howell, Olivia J Marola, Hemali Phatnani, Nancy J Philp, Debasish Sinha, Christopher B Toomey, Faith Stone, Charles Eberhart, and James T Handa

    Link

    American Hair Research Society Mentorship Grant Program: Short-Term Training Opportunities with Experts., Christopher S Potter, Victoria Ceh, Valerie D Callender, Dirk Elston, Amy McMichael, Paradi Mirmirani, Curtis Thompson, Koen Van de Wetering, and John P Sundberg

    PDF

    A new mouse mutant with a discrete mutation in Pcdhgc5 reveals that the Protocadherin γC5 isoform is not essential for dendrite arborization in the cerebral cortex., Camille M Hanes, David M Steffen, George Murray, Robert W. Burgess, Joshua A Weiner, and Andrew M Garrett

    PDF

    A new mouse mutant with a discrete mutation in Pcdhgc5 reveals that the Protocadherin γC5 isoform is not essential for dendrite arborization in the cerebral cortex., Camille M Hanes, David M Steffen, George Murray, Robert W. Burgess, Joshua A Weiner, and Andrew M Garrett

    PDF

    An inflammatory and quiescent HSC subpopulation expands with age in humans., Ksenia R Safina, Basit Salik, Dylan Kotliar, Michelle Curtis, Jonathan D Good, Chen Weng, Shawn David, Soumya Raychaudhuri, Antonia Kreso, Jennifer J. Trowbridge, Vijay G Sankaran, and Peter van Galen

    PDF

    An inflammatory and quiescent HSC subpopulation expands with age in humans., Ksenia R Safina, Basit Salik, Dylan Kotliar, Michelle Curtis, Jonathan D Good, Chen Weng, Shawn David, Soumya Raychaudhuri, Antonia Kreso, Jennifer J. Trowbridge, Vijay G Sankaran, and Peter van Galen

    PDF

    An interdisciplinary fetal neonatal neurology collaborative promotes integrative life-course brain health., Mark S Scher, Harris Eyre, Steven Donn, James M Roberts, Michael E Msall, Carolyn M Salafia, Richard Towbin, Peter N Robinson, Ken Loparo, Michael Berk, Elena Moro, Valerie Smith, Susan Ludington, Nadia Badawi, Rod W Hunt, Alistair Gunn, Harvey B Sarnat, Kirthana Kunikullaya, and Betsy Pilon

    PDF

    An ITPR1 Variant in the IP3-ITPR1 Binding Pocket Associated With a Clinical Phenotype of Athetoid Cerebral Palsy., Thania Ordaz, Jagadish Chandrabose Sundaramurthi, Adam S Arterbery, Anita M Bagley, Michael A Gargano, Jeremy P Bauer, Daniel Danis, Philip Giampietro, Ellen Raney, Lauren Rekerle, Mallory Shingle, Jon R Davids, and Peter N Robinson

    Link

    A Rare-in-Common Paradigm for Precision Genomic Medicine., Peter N Robinson

    PDF

    Artificial Intelligence and Machine Learning for Environmental Health Study., Miao Yu, Mingliang Fang, Zhenyu Tian, Bin Wang, and Douglas Walker

    PDF

    A single biomarker may not yield a reliable binary clinical answer: B cell lymphoma 6 testing and resulting interventions for endometriosis in infertility care., Arti Taggar, Amanda Ulrich, Yuliana Tan, Danielle E Luciano, Melinda Sanders, Elise T Courtois, and Claudio Benadiva

    PDF

    A single biomarker may not yield a reliable binary clinical answer: B cell lymphoma 6 testing and resulting interventions for endometriosis in infertility care., Arti Taggar, Amanda Ulrich, Yuliana Tan, Danielle E Luciano, Melinda Sanders, Elise T Courtois, and Claudio Benadiva

    Link

    A systems immunology approach reveals divergent immune profiles of RSV and SARS-CoV-2 infections in infants., Asa Thibodeau, Asuncion Mejias, Djamel Nehar-Belaid, Radu Marches, Zhaohui Xu, Giray N Eryilmaz, Steven Z Josefowicz, Bart Jones, Marie Wehenkel, Silke Paust, Virginia Pascual, Jacques Banchereau, Octavio Ramilo, and Duygu Ucar

    Link

    A systems immunology approach reveals divergent immune profiles of RSV and SARS-CoV-2 infections in infants., Asa Thibodeau, Asuncion Mejias, Djamel Nehar-Belaid, Radu Marches, Zhaohui Xu, Giray N Eryilmaz, Steven Z Josefowicz, Bart Jones, Marie Wehenkel, Silke Paust, Virginia Pascual, Jacques Banchereau, Octavio Ramilo, and Duygu Ucar

    PDF

    Auditory Stimulation Rescues Cognitive Deficit in, Mohamed Ouardouz, Amanda E Hernan, J Matthew Mahoney, and Rodney C Scott

    PDF

    Automating candidate gene prioritization with large language models: from naive scoring to literature-grounded validation., Taushif Khan, Mohammed Toufiq, Marina Yurieva, Nitaya Indrawattana, Akanitt Jittmittraphap, Nathamon Kosoltanapiwat, Pornpan Pumirat, Passanesh Sukphopetch, Muthita Vanaporn, Karolina Palucka, Basirudeen Syed Ahamed Kabeer, Darawan Rinchai, and Damien Chaussabel

    PDF

    A Xeno-Free Protocol for Rapid Differentiation of Human iPSC-Derived Microglia from the KOLF2.1J Reference Line, Nélio A J Oliveira, Katherine R Lewkowicz, Patricia A Clow, Michael E. Ward, Mark R. Cookson, William C Skarnes, and Justin A McDonough

    PDF

    A xeno-free protocol for rapid differentiation of human iPSC-derived microglia from the KOLF2.1J reference line., Nélio A J Oliveira, Katherine R Lewkowicz, Patricia A Clow, Michael E Ward, Mark R Cookson, William C Skarnes, and Justin A McDonough

    PDF

    B cells enable autoreactive T cells to avoid suppression., Matthew Funsten, Renee de Pooter, Vineeth Varanasi, Michael Burrows, Katharine Block, Andrey Kuznetsov, David V. Serreze, Haochu Huang, and Alexander Chervonsky

    PDF

    Beyond the streetlight: a TREAT-AD perspective on where to find new Alzheimer's targets., Gregory Cary, Jesse C Wiley, Gregory W. Carter, and Allan I Levey

    PDF

    Beyond the streetlight: a TREAT-AD perspective on where to find new Alzheimer's targets., Gregory Cary, Jesse C Wiley, Gregory W. Carter, and Allan I Levey

    Link

    Beyond wrinkles., Sasan Jalili and Julia Oh

    PDF

    Bi-allelic variants in BCAT1 impair mitochondrial function and are associated with a candidate neurometabolic disorder., Brianna L DiSanza, Giulia S Porcari, Livia Sertori Finoti, Leonardo Ramos-Rodriguez, Devin M Burris, Justin A McDonough, Gang Ning, Grace Fagan, Guy T Helman, Erin Weiss, Ryan J Taft, Amy Pizzino, Matthew T Whitehead, Amy Waldman, Cas Simons, Xilma Ortiz-Gonzalez, William C Skarnes, Adeline Vanderver, Elizabeth J Bhoj, and Rebecca C Ahrens-Nicklas

    PDF

    Building a genomics-capable cancer workforce: a competency-based framework for education and training in precision oncology., Amanda Drury, Yosr Hamdi, Nicola Mulder, Jens Rueter, Lindsey Kelley, Kathleen Blazer, Raffaella Casolino, and Stacy W Gray

    PDF

    Can angiotensin II affect the inflammatory response of human dental pulp cells in vitro?, Bella Luna Colombini-Ishikiriama, Thiago José Dionisio, Thais Francini Garbieri, Rafaela Alves da Silva, Sandra Helena Penha Oliveira, Vanessa Soares Lara, Andrew S Greene, and Carlos Ferreira Dos Santos

    PDF

    cGAS-STING dependent type I IFN reduces Leptospira interrogans renal colonization in mice., Suman Gupta, James Matsunaga, Bridget Ratitong, Andrew Manion, Sana Ismaeel, Diogo G Valadares, A Phillip West, Nagaraj Kerur, Christian Stehlik, Andrea Dorfleutner, Jargalsaikhan Dagvadorj, Jenifer Coburn, Andrea J Wolf, Meghan A Morrissey, Suzanne L Cassel, David A Haake, and Fayyaz S Sutterwala

    PDF

    Characterization and automated classification of sentences in the biomedical literature: a case study for biocuration of gene expression and protein kinase activity., Daniela Raciti, Kimberly M Van Auken, Valerio Arnaboldi, Christopher J Tabone, Hans-Michael Muller, and Paul W Sternberg

     

    Chlamydia muridarum Infection Impacts Murine Models of Intestinal Inflammation and Cancer., Glory Leung, Sebastian E Carrasco, Anthony J Mourino, Mert Aydin, Renata Mammone, Gregory F Sonnenberg, Gretchen Diehl, David Artis, Hiroshi Yano, Rodolfo J Ricart Arbona, and Neil S Lipman

     

    Clustering of Large Human Protein Sequences Using Spark Based Hierarchical Clustering Approach, Subhadip Paul, Utsho Banerjee, Kaustav Sengupta, Moutushi Singh, and Soumyendu Sekhar Bandyopadhyay

     

    Clustering of Large Human Protein Sequences Using Spark Based Hierarchical Clustering Approach, Subhadip Paul, Utsho Banerjee, Kaustav Sengupta, Moutushi Singh, and Soumyendu Sekhar Bandyopadhyay

    PDF

    Complete genome assemblies of two mouse subspecies reveal structural diversity of telomeres and centromeres., Bailey A Francis, Landen Gozashti, Kevin Costello, Takaoki Kasahara, Olivia S Harringmeyer, Jingtao Lilue, Tianzhen Wu, Katarzyna Zoltowska, Mohab Helmy, Tadafumi Kato, Anne M Czechanski, Iraad F Bronner, Emma Dawson, Michael A Quail, Anne Ferguson-Smith, Laura G Reinholdt, David J Adams, and Thomas M Keane

    PDF

    Conditional Stat2 Knockout Mice as a Platform for Modeling Human Diseases., Tess Cremers, Nataliya Miz, Alexandra Afanassiev, Ling Yang, Kevin P Kotredes, and Ana M Gamero

    Link

    Connecting research and clinical practice: training the next generation of translational scientists., Kate Reed, Laura Ciaccia West, Maggie Deagon, Lindsey Kelley, Therese Ingram, and Leah C. Graham

    PDF

    Consistent performance of large language models in rare disease diagnosis across ten languages and 4917 cases., Leonardo Chimirri, J Harry Caufield, Yasemin Bridges, Nicolas Matentzoglu, Michael Gargano, Mario Cazalla, Shihan Chen, Daniel Danis, Alexander J M Dingemans, Klara Gehle, Petra Gehle, Adam S L Graefe, Weihong Gu, Markus S Ladewig, Pablo Lapunzina, Julián Nevado, Enock Niyonkuru, Soichi Ogishima, Dominik Seelow, Jair A Tenorio Castaño, Marek Turnovec, Bert B A de Vries, Kai Wang, Kyran Wissink, Zafer Yüksel, Gabriele Zucca, Melissa A Haendel, Christopher J Mungall, Justin Reese, and Peter N Robinson

    PDF

    CXCR4 induces memory formation over exhaustion in CAR-T cells to achieve durable leukemia targeting., Ari Itoh-Nakadai, Minggao Liang, Michiho Shindo, Chen Bibi, Mariko Tomizawa-Murasawa, Saera Fujiki, Akiko Kaneko, Emi Kanamaru, Mari Hashimoto, Hiroshi Kajita, Yoshinari Ando, Miki Kojima, Jonathan Moody, Makoto Iwasaki, Shinsuke Takagi, Ryo Nakagawa, Saumya Agrawal, Hanae Amitani-Iijima, Kaori Sato, Yuriko Sorimachi, Nahoko Suzuki, Takehiro Fukami, Kazuharu Hanada, Satoshi Morita, Kazushige Katsura, Takehisa Matsumoto, Maiko Kobayashi, Masahiko Kato, Yasuyuki Negishi, Mikako Shirouzu, Yuho Najima, Keiyo Takubo, Chung Chau Hon, Naoyuki Uchida, Shuichi Taniguchi, Yukihide Momozawa, Piero Carninci, Leonard D. Shultz, Yoriko Saito, Michiel de Hoon, Jay W Shin, and Fumihiko Ishikawa

    PDF

    CXCR6+ natural killer cell immunotherapy preserves CD4+ T helper cells in humanized mice, Naushad Khan, Kayla Frank, and Silke Paust

    PDF

    Development of an AAV-based gene therapy for the ocular phenotype of Friedreich's ataxia., Heyu Tang, Siddhant Gupte, Emily Xu, Kaitlyn R Calabro, Hannah Friend, Sean M Crosson, Diego Fajardo, Zachary Kostamo, Hangning Zhang, James J Peterson, Fangyu Lin, Zbynek Kozmik, Cathleen Lutz, Sanford L Boye, and Shannon E Boye

    PDF

    Development of an AAV-based gene therapy for the ocular phenotype of Friedreich's ataxia., Heyu Tang, Siddhant Gupte, Emily Xu, Kaitlyn R Calabro, Hannah Friend, Sean M Crosson, Diego Fajardo, Zachary Kostamo, Hangning Zhang, James J Peterson, Fangyu Lin, Zbynek Kozmik, Cathleen Lutz, Sanford L Boye, and Shannon E Boye

    PDF

    Direct-in-NOD genetic ablation of Bcl3 leads to complete type 1 diabetes protection., Jeremy Racine, Jennifer R Dwyer, Harold D Chapman, Amy Bell, Raymond F. Robledo, and David V. Serreze

    Link

    DOCK8 and STAT3 cooperate to restrain IgE-inducing T follicular helper cells., Emily R Siniscalco, Courtney Fisher, Meng-Ping Lu, Jessica D S Grassmann, Corinne D Mack, Roukaya Yaakoubi, Danielle Jacobsen, Qian Chen, Donguk Lee, Priya Rajamanimuthu, Tregony Simoneau, Kahn Preece, Paul Gray, Satoshi Okada, Bertrand Boisson, Basak Kayaoglu, Jeffrey Danielson, Alexandra F Freeman, Jean-Laurent Casanova, Talal A Chatila, Helen C Su, Cindy S Ma, Adam Williams, Stephanie C Eisenbarth, and Uthaman Gowthaman

    PDF

    Dose-dependent IFN programs in myeloid cells after mRNA and adenovirus COVID-19 vaccination., Giray N Eryilmaz, Yilmaz Yucehan Yazici, Radu Marches, Eleni P Mimitou, Lisa Kenyon-Pesce, Kim Handrejk, Sonia Jangra, Michael Schotsaert, Adolfo García-Sastre, George A Kuchel, Jacques Banchereau, and Duygu Ucar

    PDF

    Dose-dependent IFN programs in myeloid cells after mRNA and adenovirus COVID-19 vaccination., Giray N Eryilmaz, Yilmaz Yucehan Yazici, Radu Marches, Eleni P Mimitou, Lisa Kenyon-Pesce, Kim Handrejk, Sonia Jangra, Michael Schotsaert, Adolfo García-Sastre, George A Kuchel, Jacques Banchereau, and Duygu Ucar

    PDF

    Editorial: Interdisciplinary innovations in CAR T-cell therapy for autoimmune and cancer treatment., Apostolos Zaravinos, Derya Unutmaz, and Marko Radic

    PDF

    Editorial: Interdisciplinary innovations in CAR T-cell therapy for autoimmune and cancer treatment., Apostolos Zaravinos, Derya Unutmaz, and Marko Radic

    PDF

    Educational efficacy of training videos and simulators for teaching basic mouse experimental skills to novice veterinary students., Atsushi Tsukamoto, Thum Su Zan, Makie Nitta, Hiromitsu Yoshida, Hirotaka Katahira, Yoshiharu Fujita, Satoshi Takagi, and Shinichiro Nakamura

    PDF

    Emerging AI approaches for cancer spatial omics., Javad Noorbakhsh, Ali Foroughi Pour, and Jeffrey Chuang

    PDF

    Employee Perspectives on Genetic Testing in the Workplace: Results from a National Survey., J Scott Roberts, Wendy R Uhlmann, Drew Blasco, Anya E R Prince, Sarah McCain, Subhamoy Pal, Kunal Sanghavi, Elizabeth Charnysh, and Charles Lee

    PDF

    End-of-life pathology in UM-HET3 mice treated with 16 α‑hydroxyestradiol or late‑start canagliflozin., Jessica M Snyder, David E Harrison, Ron Korstanje, Brett Ginsburg, Peter C. Reifsnyder, James Nelson, Scott Leiser, Catherine Kaczorowski, Denise M Imai, Adam B Salmon, Randy Strong, Warren Ladiges, and Richard A Miller

    PDF

    End-of-life pathology in UM-HET3 mice treated with 16 α‑hydroxyestradiol or late‑start canagliflozin., Jessica M Snyder, David E Harrison, Ron Korstanje, Brett Ginsburg, Peter C. Reifsnyder, James Nelson, Scott Leiser, Catherine Kaczorowski, Denise M Imai, Adam B Salmon, Randy Strong, Warren Ladiges, and Richard A Miller

    PDF

    Epidermal growth factor receptor regulates Beclin-1 in hyperoxic acute lung injury., Zachary M Harris, Asawari Korde, Johad Khoury, Edward P Manning, Gail Stanley, Yosep Shin, Kennedy Mitchell, Alexa von der Schulenburg, Ying Sun, Buqu Hu, Hyeon Jun Shin, John Joerns, Brian Clark, Lindsey Placek, Derya Unutmaz, Aigul Moldobaeva, Lokesh Sharma, Maor Sauler, Govindarajan Rajagopalan, Xuchen Zhang, He Wang, Mahboobe Ghaedi, Min-Jong Kang, and Jonathan L Koff

    Link

    Epigenetic reactivation of the tumor suppressor ZBTB7A by KDM4 inhibition in human acute myeloid leukemia., Alexander Arnuk, Cuijuan Han, Abimbola Eunice Lawal, Bofei Wang, Sadik Karma, Zhiping Zhang, Mhd Yousuf Yassouf, Sakthi Harini Rajendran, Harshpreet Chandok, Madeline L Eller, Sogand Sajedi, Meryl McKenna, Eve Herman, Louisa Hagen, Bettina Nadorp, Zengshuo Mo, Hector Orellana, Aristotelis Tsirigos, Pedro Miura, Hussein A Abbas, Iannis Aifantis, and Eric Wang

    Link

    Epigenetic reactivation of the tumor suppressor ZBTB7A by KDM4 inhibition in human acute myeloid leukemia., Alexander Arnuk, Cuijuan Han, Abimbola Eunice Lawal, Bofei Wang, Sadik Karma, Zhiping Zhang, Mhd Yousuf Yassouf, Sakthi Harini Rajendran, Harshpreet Chandok, Madeline L Eller, Sogand Sajedi, Meryl McKenna, Eve Herman, Louisa Hagen, Bettina Nadorp, Zengshuo Mo, Hector Orellana, Aristotelis Tsirigos, Pedro Miura, Hussein A Abbas, Iannis Aifantis, and Eric Wang

     

    Errors in pathology: The real world., Jerrold M Ward, Jeffrey C Wolf, and John P Sundberg

    PDF

    Evaluation of hippocampal DLGAP2 overexpression on cognition, synaptic function, and dendritic spine structure in a translationally relevant AD mouse model., Andrew R Ouellette, Kristen M S O'Connell, and Catherine Kaczorowski

    PDF

    Expanding and refining the Mammalian Phenotype Ontology to enhance disease model discovery., Susan M. Bello, Anna V Anagnostopoulos, Leigh Carmody, Nicolas Matentzoglu, and Cynthia Smith

    PDF

    Exploring the transformative effects of calorie restriction on the lacrimal gland in adult mice., Olivier Mauduit, Prashant Kumar, Kaitlin K Scholand, Emre Aksan, Laura Schaefer, Anmar Abu-Romman, Vanessa Delcroix, Zhiyuan Yu, Aude I Sindikubwabo, Ron Korstanje, Helen P Makarenkova, and Cintia S de Paiva

    PDF

    Extrachromosomal DNA amplifications exhibit distinct molecular characteristics and prognostic implications in gastric cancer., Seunghyun Kang, Donghyeok Seol, Jieun Lee, Chanmi Bang, Mira Yoo, Soyeon Kim, Sepil An, Hyeongjin Cho, Duyeong Hwang, So Hyun Kang, Young Suk Park, Sang-Hoon Ahn, Hyung-Ho Kim, Eunhee Yi, Sanghyun Kim, Yun-Suhk Suh, and Hoon Kim

    Link

    Extrachromosomal DNA associates with nuclear condensates and reorganizes chromatin structures to enhance oncogenic transcription., Aziz Taghbalout, Chia-Hao Tung, Patricia A Clow, Harianto Tjong, Ping Wang, Chee Hong Wong, Diane D Mao, Rahul Maurya, Meng-Fan Huang, Chew Yee Ngan, Albert H Kim, and Chia-Lin Wei

    Link

    Fasting impairs humoral immunological memory by β-hydroxybutyrate-mediated depletion of plasma cells., Yiming Zhu, Baoshan Ding, Haimei Lv, Hui Xu, Jiamei Chen, Juan Xu, Qian Wu, Xiaoxiao Hao, Yunqi Hu, Jian Guo, Jun Chen, Chaofeng Liang, Yuzhuang Li, Jiawen Wu, Nan Cao, Jijun Zhao, Guangwen Ren, Hua Jin, Yiwen Zhang, Yiping Li, Hui Zhang, and Chunliang Xu

    PDF

    Folic Acid and Methyltetrahydrofolate Supplementation in the, Karen E Christensen, Marie-Lou Faquette, Daniel Leclerc, Vafa Keser, Yan Luan, Jeanna L Bennett-Firmin, Olga V Malysheva, Alaina M Reagan, Gareth R Howell, Marie A Caudill, Teodoro Bottiglieri, and Rima Rozen

    Link

    From Home to Transcriptome: Comparing the Transcriptomic Profile of Induced Immune Response via Lipopolysaccharide Stimulation in homeRNA and Venous Blood., Lauren G Brown, Xiaofu Wei, Laura A Milton, M Yunos Alizai, James W MacDonald, Theo K Bammler, Yuting Zeng, Ingrid Robertson, Karen N Adams, Yi-Chin Toh, Damien Chaussabel, Erwin Berthier, Amanda J Haack, and Ashleigh B Theberge

    PDF

    From Human to Mouse and Back Again: Genetic and Genomic Ta(i)les of Islet Dysfunction in Type 2 Diabetes., Romy Kursawe, Khushdeep Bandesh, Sai Nivedita Krishnan, Kevin S Liu, Redwan M Bhuiyan, and Michael L. Stitzel

    PDF

    Functional equivalence of γ- and x-ray irradiation for long-term peripheral blood chimerism and acute myeloid leukemia transplant outcomes in mice., Shawn David, Griffin J Nye, Elizabeth Eudy, Ewelina Bolcun-Filas, Jennifer J. Trowbridge, and Kira Young

     

    Fundamentals of In Vitro Sampling, Katarzyna Woźniczka, Miao Yu, Nikita Looby, and Anna Roszkowska

    Link

    Funding FAIRly: A New Model for Biomedical Research., Anupam Agarwal, Kurt Marek, Nancy C Andrews, Diego R Vazquez, James Incalcaterra, Ming Lei, Howard Fox, Penny Gordon-Larsen, Jennifer K Lodge, Nick Wigginton, Kelvin Droegemeier, and The Subject Matter Expert Team of the Joint Associations Group

    Link

    Fusion of IgG antibodies to albumin inhibits transport across the placenta., Jeannette Nilsen, Kine M K Sand, Hana J Al-Khabbaz, Lennart Maximilian van Ligtenberg, Simone Mester, Line Mathiesen, Hanna T Noordzij, Kjell-Rune Jensen, Nils Leitzinger, Oda Ottersen, Sopisa Benjakul, Marie Leangen Herigstad, Fulgencio Ruso-Julve, Aina Karen Anthi, Anders Moen, Mari Nyquist-Andersen, Torleif Tollefsrud Gjølberg, Eirin Listau Bertelsen, Jason Cameron, Stian Foss, Gregory J. Christianson, Tilman Schlothauer, Tor Brynjar Stuge, Lisbeth E Knudsen, Inger Sandlie, Derry C. Roopenian, Maria Therese Ahlen, and Jan Terje Andersen

    PDF

    GA4GH phenopacket-driven characterization of genotype-phenotype correlations in Mendelian disorders., Lauren Rekerle, Daniel Danis, Filip Rehburg, Adam S L Graefe, Viktor Bily, Andrés Caballero-Oteyza, Pilar Cacheiro, Leonardo Chimirri, Jessica X Chong, Evan Connelly, Bert B A de Vries, Alexander J M Dingemans, Michael H Duyzend, Tomas Freiberger, Petra Gehle, Tudor Groza, Peter Hansen, Julius O B Jacobsen, Adam Klocperk, Markus S Ladewig, Michael I Love, Allison J Marcello, Alexander Mordhorst, Monica C Munoz-Torres, Justin Reese, Catharina Schuetz, Damian Smedley, Timmy Strauss, Ondrej Vladyka, David Zocche, Sylvia Thun, Christopher J Mungall, Melissa A Haendel, and Peter N Robinson

    PDF

    Generation and characterization of a knockout mouse of an enhancer of EBF3., Emily Cordova Hurtado, Janine M Wotton, Alexander Gulka, Crystal Burke, Jeffrey K Ng, Ibrahim Bah, Juana Manuel, Hillary Heins, Stephen A Murray, David U Gorkin, Jacqueline K White, Kevin A Peterson, and Tychele N Turner

    PDF

    Genetic and epigenetic screens in primary human T cells link candidate causal autoimmune variants to T cell networks., Ching-Huang Ho, Maxwell A Dippel, Meghan S McQuade, LeAnn P Nguyen, Arpit Mishra, Stephan Pribitzer, Samantha Hardy, Harshpreet Chandok, Florence M Chardon, Troy A McDiarmid, Hannah A DeBerg, Jane H Buckner, Jay Shendure, Carl G de Boer, Michael H Guo, Ryan Tewhey, and John P Ray

    PDF

    Genetic architecture of the murine red blood cell proteome reveals central role of hemoglobin beta cysteine 93 in maintaining redox balance., Gregory R Keele, Monika Dzieciatkowska, Ariel M Hay, Matthew Vincent, Callan O'Connor, Daniel Stephenson, Julie A Reisz, Travis Nemkov, Kirk C Hansen, Grier P Page, James C Zimring, Gary Churchill, and Angelo D'Alessandro

    PDF

    Genetic architecture of the murine red blood cell proteome reveals central role of hemoglobin beta cysteine 93 in maintaining redox balance., Gregory R Keele, Monika Dzieciatkowska, Ariel M Hay, Matthew Vincent, Callan O'Connor, Daniel Stephenson, Julie A Reisz, Travis Nemkov, Kirk C Hansen, Grier P Page, James C Zimring, Gary Churchill, and Angelo D'Alessandro

    PDF

    Genetic counselors' perspectives and experiences with workplace genetic testing: Results of a national survey., Alexandra Truhlar, Elizabeth Charnysh, Subhamoy Pal, Jonathan M Reader, Katherine Hendy, W Gregory Feero, Kerry Ryan, Alyx Vogle, Sarah McCain, Rebecca A Ferber, Jill Furnival, Charles Lee, J Scott Roberts, Wendy R Uhlmann, Kunal Sanghavi, and the INSIGHT @ Work Consortium

    PDF

    Genetic counselors' perspectives and experiences with workplace genetic testing: Results of a national survey., Alexandra Truhlar, Elizabeth Charnysh, Subhamoy Pal, Jonathan M Reader, Katherine Hendy, W Gregory Feero, Kerry Ryan, Alyx Vogle, Sarah McCain, Rebecca A Ferber, Jill Furnival, Charles Lee, J Scott Roberts, Wendy R Uhlmann, Kunal Sanghavi, and INSIGHT @ Work Consortium

    Link

    Genomic medicine year in review: 2024., Teri A Manolio, Jahnavi Narula, Alauna Rupert, Carol J Bult, Rex L Chisholm, Geoffrey S Ginsburg, Eric D Green, Gillian Hooker, Gail P Jarvik, George A Mensah, Erin M Ramos, Dan M Roden, Robb Rowley, Casey Overby Taylor, and Marc S Williams

    Link

    Genomic medicine year in review: 2025., Teri A Manolio, Alauna Rupert, Jahnavi Narula, Carol J Bult, Rex L Chisholm, Geoffrey S Ginsburg, Gillian W Hooker, Gail P Jarvik, George A Mensah, Dan M Roden, Robb Rowley, Casey Overby Taylor, Simona Volpi, and Marc S Williams

    Link

    Genotype-Environment-Driven Dysbiosis in the Skin Microbiome of Ichthyosis., Wei Zhou, Nan G Ring, Ryan Caldwell, Leonard M Milstone, and Julia Oh

    PDF

    GPR156 is required in sensory hair cells for proper auditory and vestibular function., Amandine Jarysta, Brandie Morris Verdone, Elli I Hartig, Kathleen E Cullen, and Basile Tarchini

    PDF

    Gut dysbiosis patterns in CVID patients with noninfectious complications observed in a germ-free mouse model through fecal microbiota transplantation., Joud Hajjar, Anita Y Voigt, Margaret E Conner, Alton G Swennes, Stephanie Fowler, Chadi Calarge, Danielle D Mendonca, Dominique Armstrong, Chen-Yen Chang, Jolan E Walter, Manish J Butte, Tor Savidge, Julia Oh, Farrah Kheradmand, and Joseph F Petrosino

    PDF

    Harmonizing mouse anatomy terminology: a common language?, Jesús Ruberte, Paul N Schofield, John P Sundberg, Sergi Olvera-Maneu, and Ana Carretero

    PDF

    High-quality mouse reference genomes reveal the structural complexity of the murine protein-coding landscape., Mohab Helmy, Jin U Li, Xinyu F Yan, Rachel K Meade, Elizabeth Anderson, Patrick B Chen, Anne M Czechanski, Tomás Di Domenico, Jonathan Flint, Erik Garrison, Marco T P Gontijo, Andrea Guarracino, Leanne Haggerty, Edith Heard, Kerstin Howe, Narendra Meena, Fergal J Martin, Eric A Miska, Isabell Rall, Navin B Ramakrishna, Alexandra Sapetschnig, Swati Sinha, Diandian Sun, Francesca F Tricomi, Runjia Qu, Jonathan M D Wood, Tianzhen Wu, Dian J Zhou, Laura G Reinholdt, David J Adams, Clare M Smith, Jingtao Lilue, and Thomas M Keane

    PDF

    High-quality mouse reference genomes reveal the structural complexity of the murine protein-coding landscape., Mohab Helmy, Jin U Li, Xinyu F Yan, Rachel K Meade, Elizabeth Anderson, Patrick B Chen, Anne M Czechanski, Tomás Di Domenico, Jonathan Flint, Erik Garrison, Marco T P Gontijo, Andrea Guarracino, Leanne Haggerty, Edith Heard, Kerstin Howe, Narendra Meena, Fergal J Martin, Eric A Miska, Isabell Rall, Navin B Ramakrishna, Alexandra Sapetschnig, Swati Sinha, Diandian Sun, Francesca F Tricomi, Runjia Qu, Jonathan M D Wood, Tianzhen Wu, Dian J Zhou, Laura G Reinholdt, David J Adams, Clare M Smith, Jingtao Lilue, and Thomas M Keane

    PDF

    Host-specific bacterial modulation of airway gene expression and alternative splicing., Mian Horvath, Hyeon Gu Kang, Te-Chia Wu, Elizabeth Aiken, Diana Cadena Castaneda, Sema Akkurt, Florentina Marches, Olga Anczuków, Karolina Palucka, and Julia Oh

    Link

    How the microbiome shapes epigenetic trained memory in neuroinflammation: Implications for neurodegenerative diseases., Mian Horvath and Jaime Imitola

    Link

    Human iPSC-derived microglia sense and dampen hyperexcitability of cortical neurons carrying the epilepsy-associated, Zhefu Que, Maria I Olivero-Acosta, Morgan Robinson, Ian Chen, Jingliang Zhang, Kyle Wettschurack, Jiaxiang Wu, Tiange Xiao, C Max Otterbacher, Vinayak Shankar, Hope Harlow, Seoyong Hong, Benjamin Zirkle, Muhan Wang, Ningren Cui, Purba Mandal, Xiaoling Chen, Brody Deming, Manasi Halurkar, Yuanrui Zhao, Jean-Christophe Rochet, Ranjie Xu, Amy L Brewster, Long-Jun Wu, Chongli Yuan, William C Skarnes, and Yang Yang

    PDF

    Humanized Mouse Models for Type 1 Diabetes., David V. Serreze, Marissa Tousey-Pfarrer, and Jeremy Racine

    PDF

    Human microglia in brain assembloids display region-specific diversity and respond to hyperexcitable neurons carrying, Jiaxiang Wu, Xiaoling Chen, Jingliang Zhang, Kyle Wettschurack, Morgan Robinson, Weihao Li, Yuanrui Zhao, Ye-Eun Yoo, Brody A Deming, Yue Shu, Akila D Abeyaratna, Zhefu Que, Dongshu Du, Matthew Tegtmeyer, Chongli Yuan, William C Skarnes, Zhong-Yin Zhang, Jean-Christophe Rochet, Long-Jun Wu, and Yang Yang

    PDF

    Human microglia in brain assembloids display region-specific diversity and respond to hyperexcitable neurons carrying, Jiaxiang Wu, Xiaoling Chen, Jingliang Zhang, Kyle Wettschurack, Morgan Robinson, Weihao Li, Yuanrui Zhao, Ye-Eun Yoo, Brody A Deming, Yue Shu, Akila D Abeyaratna, Zhefu Que, Dongshu Du, Matthew Tegtmeyer, Chongli Yuan, William C Skarnes, Zhong-Yin Zhang, Jean-Christophe Rochet, Long-Jun Wu, and Yang Yang

    PDF

    Identifying genetic determinants of outer retinal function in mice using a large-scale gene-targeted screen., Janine M Wotton, Mark P. Krebs, Riccardo Sangermano, Jessica Wong, Cynthia Smith, Amelia M Willett, Douglas Howell, Abby Jones, Catherine Witmeyer, Jacob P Lowy, Michael McFarland, Stephen A Murray, Robert E Braun, Patsy M. Nishina, Eric A Pierce, Emily M Place, Kinga M Bujakowska, Neal S Peachey, and Jacqueline K White

    PDF

    Identifying transcriptomic signatures that mediate the causal effect of genotype on Alzheimer's disease., Simran Kaur, Anna L. Tyler, Giovanna L Durante, Gregory Cary, Gregory W. Carter, and J Matthew Mahoney

    PDF

    IFN signaling is associated with radiotherapy response in malignant peripheral nerve sheath tumors., Iowis Zhu, Julian Chien, Gabriel E Rech, Kanish Mirchia, Sixuan Pan, Kaeli Miller, Joanna Pak, Rosanna Wustrack, Varun Monga, Steve E Braunstein, Mark D Adams, Line Jacques, Melike Pekmezci, S John Liu, and Harish N Vasudevan

    PDF

    IFN signaling is associated with radiotherapy response in malignant peripheral nerve sheath tumors., Iowis Zhu, Julian Chien, Gabriel E Rech, Kanish Mirchia, Sixuan Pan, Kaeli Miller, Joanna Pak, Rosanna Wustrack, Varun Monga, Steve E Braunstein, Mark D Adams, Line Jacques, Melike Pekmezci, S John Liu, and Harish N Vasudevan

    PDF

    IL1A enhances TNF-induced retinal ganglion cell death., Katherine M Andersh, Michael MacLean, Gareth R Howell, and Richard T Libby

    PDF

    IL1A enhances TNF-induced retinal ganglion cell death., Katherine M Andersh, Michael MacLean, Gareth R Howell, and Richard T Libby

    PDF

    Improving gene isoform quantification with miniQuant., Haoran Li, Dingjie Wang, Qi Gao, Puwen Tan, Yunhao Wang, Xiaoyu Cai, Aifu Li, Yue Zhao, Andrew L Thurman, Seyed Amir Malekpour, Ying Zhang, Roberta Sala, Andrea Cipriano, Chia-Lin Wei, Vittorio Sebastiano, Chi Song, Nancy R Zhang, and Kin Fai Au

    PDF

    Improving gene isoform quantification with miniQuant., Haoran Li, Dingjie Wang, Qi Gao, Puwen Tan, Yunhao Wang, Xiaoyu Cai, Aifu Li, Yue Zhao, Andrew L Thurman, Seyed Amir Malekpour, Ying Zhang, Roberta Sala, Andrea Cipriano, Chia-Lin Wei, Vittorio Sebastiano, Chi Song, Nancy R Zhang, and Kin Fai Au

    PDF

    Improving rigor and reproducibility through implementation of the ISSCR standards for human stem cell use in research., Yvonne Fischer, Jack Mosher, Ivana Barbaric, Claudia Spits, and Martin Pera

    PDF

    Improving rigor and reproducibility through implementation of the ISSCR standards for human stem cell use in research., Yvonne Fischer, Jack Mosher, Ivana Barbaric, Claudia Spits, and Martin Pera

    PDF

    Inborn errors of immunity: Manifestation, treatment, and outcome-an ESID registry 1994-2024 report on 30,628 patients., Gerhard Kindle, Mickaël Alligon, Michael H Albert, Matthew Buckland, J David Edgar, Benjamin Gathmann, Sujal Ghosh, Antonios Gkantaras, Alexandra Nieters, Claudio Pignata, Peter N Robinson, Stephan Rusch, Catharina Schuetz, Svetlana Sharapova, Benjamin Shillitoe, Fabio Candotti, Andrew J Cant, Jean-Laurent Casanova, Amos Etzioni, Alain Fischer, Isabelle Meyts, Luigi D Notarangelo, Martine Pergent, C I Edvard Smith, ESID Registry Working Party, Lennart Hammarström, Bodo Grimbacher, Mikko R J Seppänen, Nizar Mahlaoui, Stephan Ehl, and Markus G Seidel

     

    In-depth human phenotype ontology curation boosts prioritization performance for Netherton syndrome (SPINK5-syndromic epidermal differentiation disorder)., Edwin Cuperus, Suzanne G M A Pasmans, Henry L Han, Adam S Arterbery, Daniel Danis, Michel van Geel, Cristina Has, Lisa Weibel, Katariina Hannula-Jouppi, Christine Bodemer, Alain Hovnanian, Peter N Robinson, and Mariëlle E van Gijn

    PDF

    Inflammatory stromal and T cells mediate human bone marrow niche remodeling in clonal hematopoiesis and myelodysplasia., Karin D Prummel, Kevin Woods, Maksim Kholmatov, Eric C Schmitt, Evi P Vlachou, Mayssa Labyadh, Rebekka Wehner, Gereon Poschmann, Kai Stühler, Susann Winter, Uta Oelschlaegel, Manja Wobus, Logan S Schwartz, Pedro L Moura, Eva Hellström-Lindberg, Krishnaraj Rajalingam, Matthias Theobald, Jennifer J. Trowbridge, Clémence Carron, Thierry Jaffredo, Marc Schmitz, Uwe Platzbecker, Judith B Zaugg, and Borhane Guezguez

    PDF

    Inhibition of Moesin and CD44 in stem cell-derived neurons affects the pathological genetic signature associated with Alzheimer's disease., Eiden H Brewer, Charles A Williams, Gregory Cary, Ranjita Betarbet, Inez K A Pranoto, Elizabeth L Zoeller, Haian Fu, Allan I Levey, Jesse C Wiley, Gregory W. Carter, Jessica E Young, and TREAT-AD Consortium

    PDF

    Inner ear deficits complicate interpretation of depression-like behaviors in, Basile Tarchini, Ruth Anne Eatock, Katie S Kindt, Cesare Orlandi, and Kathleen E Cullen

    PDF

    Integrated phenotypic and proteomic screening identifies top-tier Alzheimer's disease therapeutic targets., Gregory Cary, Qianjin Li, Jesse C Wiley, Carolyn Paisie, Yuhong Du, Elizabeth L Zoeller, Duc Duong, Haian Fu, Nicholas T Seyfried, Allan I Levey, Ranjita Betarbet, Gregory W. Carter, and The Emory-Sage-SGC-JAX TREAT-AD Center

    PDF

    Integration of a neuronal RNAseq dataset with the draft Gryllus bimaculatus transcriptome refines gene predictions and highlights potential systematic response to injury., Felicia F Wang, Harrison P Fisher, Lisa M Ledwidge, Joel H Graber, Riley A Grindle, Jarod A Rollins, and Hadley W Horch

    PDF

    Integrative Multiomic Classification Reveals Distinct Origins and Evolutionary Trajectories of Thymic Epithelial Tumors., Seongyeol Park, Kijong Yi, Jieun Lee, Myung Jin Yang, Joo-Hye Song, Joonoh Lim, Taewoo Kim, Seokhwi Kim, Su Yeon Kim, Hyung-Don Kim, Yoon Ho Kim, Sae Bom Lee, Yoo Jin Jung, Hansol Park, Jake June-Koo Lee, Yohan An, Jeonghwan Youk, Kwon Joong Na, Samina Park, Hyun Joo Lee, In Kyu Park, Chang Hyun Kang, Eui-Cheol Shin, Tae Min Kim, Won Do Heo, Charles Lee, Gou Young Koh, Sung-Yup Cho, Young Seok Ju, and Young Tae Kim

    PDF

    Integrative Multiomic Classification Reveals Distinct Origins and Evolutionary Trajectories of Thymic Epithelial Tumors., Seongyeol Park, Kijong Yi, Jieun Lee, Myung Jin Yang, Joo-Hye Song, Joonoh Lim, Taewoo Kim, Seokhwi Kim, Su Yeon Kim, Hyung-Don Kim, Yoon Ho Kim, Sae Bom Lee, Yoo Jin Jung, Hansol Park, Jake June-Koo Lee, Yohan An, Jeonghwan Youk, Kwon Joong Na, Samina Park, Hyun Joo Lee, In Kyu Park, Chang Hyun Kang, Eui-Cheol Shin, Tae Min Kim, Won Do Heo, Charles Lee, Gou Young Koh, Sung-Yup Cho, Young Seok Ju, and Young Tae Kim

    Link

    Interplay between cohesin and RNA polymerase II in regulating chromatin interactions and gene transcription., Minji Kim, Ping Wang, Patricia A Clow, Eli Chien, Xiaotao Wang, Jianhao Peng, Haoxi Chai, Xiyuan Liu, Byoungkoo Lee, Chew Yee Ngan, Olgica Milenkovic, Jeffrey Chuang, Chia-Lin Wei, Rafael Casellas, Albert Cheng, and Yijun Ruan

    Link

    Interplay between cohesin and RNA polymerase II in regulating chromatin interactions and gene transcription., Minji Kim, Ping Wang, Patricia A Clow, Eli Chien, Xiaotao Wang, Jianhao Peng, Haoxi Chai, Xiyuan Liu, Byoungkoo Lee, Chew Yee Ngan, Olgica Milenkovic, Jeffrey Chuang, Chia-Lin Wei, Rafael Casellas, Albert Cheng, and Yijun Ruan

    PDF

    In utero rescue of neurological dysfunction in a mouse model of Wiedemann-Steiner syndrome., Tinna Reynisdottir, Kimberley J Anderson, Katrin Möller, Stefán Pétursson, Andrew Brinn, Katheryn P Franklin, Juan Ouyang, Asbjorg O Snorradottir, Cathleen Lutz, Aamir Zuberi, Valerie B DeLeon, and Hans T Bjornsson

     

    iRhom2 deletion protects against diabetic neuropathy by suppressing neuroinflammation., Vitoria Mattos Pereira, Isabelle Dove Wasseen, Zhaojie Zhang, Qian-Quan Sun, Vishnu Hosur, Kelly C S Roballo, and Sreejayan Nair

     

    iRhom2 deletion protects against diabetic neuropathy by suppressing neuroinflammation., Vitoria Mattos Pereira, Isabelle Dove Wasseen, Zhaojie Zhang, Qian-Quan Sun, Vishnu Hosur, Kelly C S Roballo, and Sreejayan Nair

    PDF

    JAX Animal Behavior System (JABS), a genetics-informed, end-to-end advanced behavioral phenotyping platform for the laboratory mouse., Anshul Choudhary, Brian Q Geuther, Thomas J. Sproule, Glen L Beane, Vivek Kohar, Jarek Trapszo, and Vivek Kumar

    PDF

    JAX Animal Behavior System (JABS), a genetics-informed, end-to-end advanced behavioral phenotyping platform for the laboratory mouse., Anshul Choudhary, Brian Q Geuther, Thomas J. Sproule, Glen L Beane, Vivek Kohar, Jarek Trapszo, and Vivek Kumar

    PDF

    Legislating infrastructure: a state-level model to accelerate endometriosis research and women's health equity., E T Courtois, L Roy, Jasmina Uvalic, K Mullaj, D Lockshire, and D E Luciano

    PDF

    Life-extending interventions do not necessarily result in compression of morbidity: a case example offering a robust statistical approach., Deependra K Thapa, Wasiuddin Najam, Erik S Parker, Xi Rita Wang, Daniel L Smith, Ufuk Beyaztas, James F Nelson, Steven N Austad, Gary Churchill, and David B Allison

    PDF

    Life-extending interventions do not necessarily result in compression of morbidity: a case example offering a robust statistical approach., Deependra K Thapa, Wasiuddin Najam, Erik S Parker, Xi Rita Wang, Daniel L Smith, Ufuk Beyaztas, James F Nelson, Steven N Austad, Gary Churchill, and David B Allison

    PDF

    Longitudinal analysis of body weight reveals homeostatic and adaptive traits linked to lifespan in diversity outbred mice., G V Prateek, Zhenghao Chen, Kevin Wright, Andrea Di Francesco, Vladimir Jojic, Gary Churchill, and Anil Raj

    PDF

    Longitudinal analysis of body weight reveals homeostatic and adaptive traits linked to lifespan in diversity outbred mice., G V Prateek, Zhenghao Chen, Kevin Wright, Andrea Di Francesco, Vladimir Jojic, Gary Churchill, and Anil Raj

    PDF

    Low-coverage whole-genome sequencing facilitates accurate and cost-effective haplotype reconstruction in complex mouse crosses., Samuel J Widmayer, Lydia K Wooldridge, Emily Swanzey, Mary Barter, Chrystal M Snow, Michael C Saul, Qingchang Meng, Beth L Dumont, Laura G Reinholdt, and Daniel M Gatti

    Link

    Male-biased Yap1-Cd276/B7-H3 axis for immune evasion in medulloblastoma., Nourhan Abdelfattah, Sivaraman Natarajan, Han Nhat Tran, Thomas Wong, Maryam Faisal, Jose Maldonado, Rachael McMinimy, Hannah Borland, Shu-Hsia Chen, Hong Zhao, Matthew Vasquez, Freddys F Rodriguez, Carston R Wagner, Fernando Camargo, James Olson, Joshy George, and Kyuson Yun

    PDF

    Mapping the genetic landscape across 14 psychiatric disorders., Andrew D Grotzinger, Josefin Werme, Wouter J Peyrot, Oleksandr Frei, Christiaan de Leeuw, Lucy K Bicks, Qiuyu Guo, Michael P Margolis, Brandon J Coombes, Anthony Batzler, Vanessa Pazdernik, Joanna M Biernacka, Ole A Andreassen, Verneri Anttila, Anders D Børglum, Gerome Breen, Na Cai, Ditte Demontis, Howard J Edenberg, Stephen V Faraone, Barbara Franke, Michael J Gandal, Joel Gelernter, Alexander S Hatoum, John M Hettema, Emma C Johnson, Katherine G Jonas, James A Knowles, Karestan C Koenen, Adam X Maihofer, Travis T Mallard, Manuel Mattheisen, Karen S Mitchell, Benjamin M Neale, Caroline M Nievergelt, John I Nurnberger, Kevin S O'Connell, Roseann E Peterson, Elise B Robinson, Sandra S Sanchez-Roige, Susan L Santangelo, Jeremiah M Scharf, Hreinn Stefansson, Kari Stefansson, Murray B Stein, Nora I Strom, Laura M Thornton, Elliot M Tucker-Drob, Brad Verhulst, Irwin D Waldman, G Bragi Walters, Naomi R Wray, Dongmei Yu, Anxiety Disorders Working Group of the Psychiatric Genomics Consortium, Attention-Deficit/Hyperactivity Disorder Working Group of the Psychiatric Genomics Consortium, Autism Spectrum Disorders Working Group of the Psychiatric Genomics Consortium, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Eating Disorders Working Group of the Psychiatric Genomics Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Nicotine Dependence GenOmics (INDIGO) Consortium, Obsessive-Compulsive Disorder and Tourette Syndrome Working Group of the Psychiatric Genomics Consortium, Post-Traumatic Stress Disorder Working Group of the Psychiatric Genomics Consortium, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Substance Use Disorders Working Group of the Psychiatric Genomics Consortium, Phil H Lee, Kenneth S Kendler, and Jordan W Smoller

    PDF

    Meta-analysis of genetic mapping studies in mice reveals candidate epilepsy modifier genes that are outside the current drug development landscape., Giovanna L Durante, Anna L. Tyler, Rod C Scott, Amanda E Hernan, and J Matthew Mahoney

    PDF

    Meta-analysis of genetic mapping studies in mice reveals candidate epilepsy modifier genes that are outside the current drug development landscape., Giovanna L Durante, Anna L. Tyler, Rod C Scott, Amanda E Hernan, and J Matthew Mahoney

    PDF

    Metabolomic and lipidomic atlas of human hair across its length., Maria van de Lavoir, Yuanye Chi, Ting Zeng, Rani Robeyns, Maria Del Mar Delgado Povedano, Leen Jacobs, Celine Gys, Hugo Neels, Shuzhao Li, Alexander L N van Nuijs, and Adrian Covaci

    PDF

    Metallothionein 1 mediates growth and survival of Dnmt3a;Npm1-mutant acute myeloid leukemia, Patricia A Colom Díaz, Jayna J Mistry, Kira Young, Chih-Hsing Chou, Nathan Boyer, Ross L Levine, Nathan Salomonis, H Leighton Grimes, and Jennifer J. Trowbridge

    PDF

    miR155, triplicated in Down syndrome, regulates the development of neural stem cells and GABAergic interneurons in Alzheimer's disease mouse and human iPSC models., Xiaodong Zhu, Jean-Vianney Haure-Mirande, Mesude Bicak, Pengfei Dong, Ilya Kruglikov, Aiqun Li, Aisha Al-Subaie, Valentina Fossati, Scott Noggle, Sam Gandy, and Michelle E Ehrlich

    Link

    miRNA checking meiosis., Mary Ann Handel

    Link

    miRNA checking meiosis., Mary Ann Handel

    Link

    Mislocalization of KCNQ2 Channels as a Pathogenic Mechanism in KCNQ2 Developmental and Epileptic Encephalopathy., Kristen Springer, Heun Soh, Raquel Paz Zavala, Nissi Varghese, Cathleen Lutz, Aamir Zuberi, Alexander C Jackson, and Anastasios V Tzingounis

    PDF

    Misregulated alternative splicing in endometriosis: a role for aberrant mRNA variants in endometriotic cell growth., Venkata Naga Goutham Davuluri, Michelle Dias, Roxanna Llinas, Neha Kamath, Pooja Popli, Shannon M Hawkins, Chandrakant Tayade, Elise T Courtois, Hari Krishna Yalamanchili, and Ramakrishna Kommagani

    PDF

    MKK4 and MKK7 control degeneration of retinal ganglion cell somas and axons after glaucoma-relevant injury., Olivia J Marola, Stephanie B Syc-Mazurek, Sarah E R Yablonski, Peter G Shrager, Simon W M John, and Richard T Libby

    Link

    Modest increase in the de novo single-nucleotide mutation rate in house mice born by assisted reproduction., Laura Blanco-Berdugo, Alexis Garretson, and Beth L Dumont

    PDF

    Molecular Systems Biology at 20: reflecting on the past, envisioning the future., Poonam Bheda, Jingyi Hou, Ruedi Aebersold, Uri Alon, Joel S Bader, Lee Bardwell, Edison Liu, James C W Locke, Matthias Mann, Andrew J Millar, Felix Naef, Yitzhak Pilpel, Ron Shamir, and Dennis Vitkup

    PDF

    Mondo: integrating disease terminology across communities., Nicole A Vasilevsky, Sabrina Toro, Nicolas Matentzoglu, Joseph E Flack, Kathleen R Mullen, Harshad Hegde, Sarah Gehrke, Patricia L Whetzel, Yousif Shwetar, Nomi L Harris, Mee S Ngu, Gioconda L Alyea, Megan S Kane, Paola Roncaglia, Eric Sid, Courtney L Thaxton, Valerie Wood, Roshini S Abraham, Maria Isabel Achatz, Pamela Ajuyah, Joanna S Amberger, Lawrence Babb, Jasmine Baker, James P Balhoff, Jonathan S Berg, Amol Bhalla, Xavier Bofill-De Ros, Ian R Braun, Eleanor C Broeren, Blake K Byer, Alicia B Byrne, Tiffany J Callahan, Leigh Carmody, Lauren E Chan, Amanda R Clause, Julie S Cohen, Marcello DeLuca, Natalie T Deuitch, May Flowers, Jamie Fraser, Toyofumi Fujiwara, Vanessa Gitau, Jennifer L Goldstein, Dylan Gration, Tudor Groza, Benjamin M Gyori, William Hankey, Jason A Hilton, Daniel S Himmelstein, Stephanie S Hong, Charles T Hoyt, Robert Huether, Eric Hurwitz, Julius O B Jacobsen, Atsuo Kikuchi, Sebastian Köhler, Daniel R Korn, David Lagorce, Bryan J Laraway, Jane Y Li, Adriana J Malheiro, James McLaughlin, Birgit H M Meldal, Shruthi Mohan, Sierra A T Moxon, Monica C Munoz-Torres, Tristan H Nelson, Frank W Nicholas, David Ochoa, Daniel Olson, Tudor I Oprea, Tomiko T Oskotsky, David Osumi-Sutherland, Kelley Paris, Helen E Parkinson, Zoë M Pendlington, Xiao P Peng, Amy Pizzino, Sharon E Plon, Bradford C Powell, Julie C Ratliff, Heidi L Rehm, Lyubov Remennik, Erin R Riggs, Sean Roberts, Peter N Robinson, Justyne E Ross, Kevin Schaper, Brian M Schilder, Johanna L Schmidt, Elliott W Sharp, Morgan N Similuk, Damian Smedley, Tam P Sneddon, Rachel Sparks, Ray Stefancsik, Gregory S Stupp, Shilpa Sundar, Terue Takatsuki, Imke Tammen, Kezang C Tshering, Deepak R Unni, Eloise Valasek, Adeline Vanderver, Alex H Wagner, Ryan F Webb, Danielle Welter, Doron Yaya-Stupp, Andreas Zankl, Xingmin Aaron Zhang, Julie A McMurry, Christopher G Chute, Ada Hamosh, Christopher J Mungall, and Melissa A Haendel

    Link

    Morally relevant features warranting ethical oversight in human stem cell-based embryo models., Naomi Moris, Alfonso Martinez Arias, Martin Pera, Nicolas Rivron, Karen Sermon, and Nienke de Graeff

    Link

    Multicenter Histology Image Integration and Multiscale Deep Learning Support Machine Learning-Enabled Pediatric Sarcoma Classification., Adam H Thiesen, Sergii Domanskyi, Ali Foroughi Pour, Jingyan Zhang, Todd B Sheridan, Steven Neuhauser, Alyssa Stetson, Katelyn Dannheim, Jonathan C Henriksen, Danielle B Cameron, Shawn Ahn, Hao Wu, Emily R Christison Lagay, Carol J Bult, Eleanor Y Chen, Jeffrey Chuang, and Jill C Rubinstein

    Link

    Multiple Mechanisms Contribute to Robust Type 1 Diabetes Protection in Nfkbid- Overexpressing NOD Mice., Jennifer R Dwyer, Jeremy Racine, Harold D Chapman, Amy Bell, Anna Quinlan, Grace Stafford, and David V. Serreze

    PDF

    Multiscale metabolic covariance networks uncover stage-specific biomarker signatures across the Alzheimer's disease continuum., Juan Antonio K Chong Chie, Scott A Persohn, Ravi S Pandey, Olivia R Simcox, Gregory W. Carter, Paul Salama, Paul R Territo, and the Alzheimer’s Disease Neuroimaging Initiative

     

    NADPH Oxidase 4 and Metabolic Stress in Dahl Salt-Sensitive Rat Kidneys., Satoshi Shimada, Chun Yang, Brian Hoffmann, Timothy M Stearns, Theresa Kurth, Mingyu Liang, Ranjan K Dash, and Allen W Cowley

     

    NADPH Oxidase 4 and Metabolic Stress in Dahl Salt-Sensitive Rat Kidneys., Satoshi Shimada, Chun Yang, Brian Hoffmann, Tim J Stodola, Theresa Kurth, Mingyu Liang, Ranjan K Dash, and Allen W Cowley

    PDF

    NBL1 associates with renal phenotypes in mice, but partial Nbl1 reduction does not ameliorate kidney disease., Courtney Willey, Rei Bufi, Yuka Takemon, Abigail Brackett, Alicia Warren, Samantha Spellacy, Daniel M Gatti, Susan Sheehan, and Ron Korstanje

    PDF

    Neurological, metabolic and inflammatory phenotypes in a mouse model of ECHS1 deficiency., Meghan M Eller, Aamir Zuberi, Xiaorong Fu, Alina P Montalbano, Felix Nitschke, Shawn C Burgess, Cathleen Lutz, and Rachel M Bailey

    PDF

    Neurometabolic and vascular dysfunction as an early diagnostic for Alzheimer's disease and related dementias., Juan Antonio K Chong Chie, Scott A Persohn, Ravi S Pandey, Gregory W. Carter, Olivia R Simcox, Paul Salama, Paul R Territo, and the Alzheimer’s Disease Neuroimaging Initiative

    PDF

    New Viability Assays for Acanthamoeba castellanii Trophozoites and Cysts Allow Rapid Assessment of Drug Activity., Carrie A Flynn, Rebecca I Colón-Ríos, Andrew Harmez, William F Flynn, and Barbara I Kazmierczak

    PDF

    New Viability Assays for Acanthamoeba castellanii Trophozoites and Cysts Allow Rapid Assessment of Drug Activity., Carrie A Flynn, Rebecca I Colón-Ríos, Andrew Harmez, William F Flynn, and Barbara I Kazmierczak

    PDF

    NRN1 as a therapeutic target for Alzheimer's disease., Derian A Pugh, Gregory Cary, Kelsey M Greathouse, Lauren C Nassour-Caswell, Emma L Hobby, Nicholas T Seyfried, and Jeremy H Herskowitz

    PDF

    NRN1 as a therapeutic target for Alzheimer's disease., Derian A Pugh, Gregory Cary, Kelsey M Greathouse, Lauren C Nassour-Caswell, Emma L Hobby, Nicholas T Seyfried, and Jeremy H Herskowitz

    Link

    Olaparib in Patients With Solid Tumors With, Tareq Al Baghdadi, Michael Rothe, Pam K Mangat, Elizabeth Garrett-Mayer, Oxana V Crysler, Kathryn F Mileham, Laura Catherine Farrington, Bamidele Adesunloye, Stephanie A Dublis, Igor Astsaturov, Carmen J Calfa, Jonathan Bleeker, Maya Khalil, Ramya Thota, Timothy L Cannon, Olatunji B Alese, Philip J Gold, Navid Hafez, Ari D Baron, Funda Meric-Bernstam, Evthokia Hobbs, Alissa S Marr, Jens Rueter, Bernard Tawfik, Dominique C Hinshaw, Abigail Gregory, Gina N Grantham, Susan Halabi, and Richard L Schilsky

    Link

    Olaparib in Patients With Solid Tumors With ATM Alterations: Results From the Targeted Agent and Profiling Utilization Registry (TAPUR) Study, Daniel R Carrizosa, Michael Rothe, Pam K Mangat, Elizabeth Garrett-Mayer, Deepti Behl, Bamidele Adesunloye, Evan Pisick, Kathleen W Beekman, Efrat Dotan, Mehmet Akce, Olatunji B Alese, Vaibhav Sahai, Kelsey A Klute, Jeanny B Aragon-Ching, Kathrine A Cooper, Ramya Thota, Funda Meric-Bernstam, Peter J Hosein, Erika C Maestas, Justin T Moyers, Steven Powell, Song Zhao, Evthokia Hobbs, Jens Rueter, Davendra P S Sohal, Mark A Taylor, Dominique C Hinshaw, Abigail Gregory, Gina N Grantham, Susan Halabi, and Richard L Schilsky

    PDF

    OmNI: a modular open-source framework for interactive multi-omics data integration and visualization., Grace Potter, Jacob A Beierle, Camron Bryant, Sadhna Phanse, Carl White, Andrew Emili, and Indranil Paul

    PDF

    Oncopacket: integration of cancer research data using GA4GH phenopackets., Michael Sierk, Daniel Danis, Sujay Patil, Nobal Kishor, Rajdeep Mondal, Abhishek Jha, Qingrong Chen, Chunhua Yan, Monica Munoz-Torres, Daoud Meerzaman, Peter N Robinson, and Justin T Reese

    PDF

    Opportunities and considerations for using artificial intelligence in bioinformatics education., Stephen R Piccolo, Aparna Nathan, Michelle D Brazas, Manoj Kandpal, Aida T Miró-Herrans, Adam J Kleinschmit, Susan McClatchy, Pertunia Mutheiwana, Dusanka Nikolic, Luciana I Gallo, Rolanda Sunaye Julius, Marta Lloret-Llinares, Nicola Mulder, Danielle Presgraves, Sonal Shewaramani, Jorge Xool-Tamayo, Frédéric J J Chain, and Silvia Arantza Sanchez Guerrero

    PDF

    Optimizing human FcRn mouse models to improve pharmacokinetic evaluation of antibody drug candidates., Gregory J. Christianson, Zachary M Howard, Samantha Kenney, Emily Lowell, Nijaguna Bethur, Derry C. Roopenian, and Elena Gonzalo-Gil

    PDF

    Optimizing human FcRn mouse models to improve pharmacokinetic evaluation of antibody drug candidates., Gregory J. Christianson, Zachary M Howard, Samantha Kenney, Emily Lowell, Nijaguna Bethur, Derry C. Roopenian, and Elena Gonzalo-Gil

    Link

    Optimizing the characterization and quantification of retinal ganglion cell somas in healthy and injured retinas using cellpose., Sarah E R Yablonski, Abigail Bishop, Sean D Lydon, Ivan Zhu, Nicole Wang, Olivia J Marola, and Richard T Libby

    Link

    Optimizing the characterization and quantification of retinal ganglion cell somas in healthy and injured retinas using cellpose., Sarah E R Yablonski, Abigail Bishop, Sean D Lydon, Ivan Zhu, Nicole Wang, Olivia J Marola, and Richard T Libby

    PDF

    Overcoming EGFR-Mediated Dendritic Cell Dysfunction to Enhance Anti-tumor Immunity in EGFR-Mutant NSCLC by Precisely Targeting CD73 With pH-responsive Nanocarriers., Xiaoling Shang, Xudong Geng, Zixu Wang, Shumin Yuan, Shanshan Ding, Ni Liu, Xinchun Ma, Xuan Sun, Huimin Wang, Ying Sun, Xun Qu, Guangwen Ren, Yong Qiang Li, Xiuwen Wang, and Yanguo Liu

    PDF

    PAK1 inhibitor NVS-PAK1-1 preserves dendritic spines in amyloid/tau exposed neurons and 5xFAD mice., Tao Yang, Hasi Huhe, Sean-Paul Williams, Sukhneet Kaur, Yeonglong Albert Ay, Zachary W Davis-Gilbert, Gregory Cary, Carolyn Paisie, Robert R Butler, Jesse Wiley, Ranjita Betarbet, Haian Fu, Duc Duong, Nicholas T Seyfried, Karina Leal, Gregory W. Carter, Aled Edwards, Allan I Levey, Jacob L Capener, David H Drewry, Mohammad A Hossain, Hans J Oh, Alison D Axtman, Stacey J Sukoff Rizzo, Frank M Longo, and The Emory-Sage-SGC-JAX TREAT-AD Center

    PDF

    PD-L1 is an intrinsic switch for natural killer cell-mediated, TRAIL-dependent antiviral function., Kayla Frank, Himani Sharma, Efthymios Motakis, Nooshin Nourbakhsh, Shawn Abeynaike, Tridu R Huynh, Cheryl A Jones, Scott K Johnson, S Mark Tompkins, and Silke Paust

    PDF

    Perspectives from the 2025 ISCBI/ISCI joint workshop on genetic stability, clonal monitoring, ethical data governance, and global inclusion in stem cell banking., Jung-Hyun Kim, Andreas Kurtz, Ivana Barbaric, Maneesha S Inamdar, Martin Pera, Nissim Benvenisty, Nika Shakiba, Rosario Isasi, Tadaaki Hanatani, and Glyn Stacey

     

    Pharmacological Treatment for Adamantinomatous Craniopharyngioma., Chuan Zhao, Bo Zhang, Wenhao An, Yi Lin, Junping Zhang, Ching C Lau, Quan Cheng, and Zhixiong Lin

    PDF

    Phenotype specific nuclear lamina remodeling in hiPSC derived cardiomyocytes bearing, Isabella Leite Coscarella, Olalekan H Usman, Lili Wang, Maicon Landim-Vieira, Lillian Wirstiuk, Amber N Brown, Diego A R Zorio, Brian K Washburn, Cynthia Vied, Bjorn C Knollmann, Christopher Solís, Vitold E Galkin, P Bryant Chase, J Travis Hinson, Jerome Irianto, and Jose Renato Pinto

    Link

    Planar polarized organization of mouse hair cells is established and maintained by STK32A, GPR156 and EMX2., Shihai Jia, Ellison J Goodrich, Basile Tarchini, and Michael R Deans

    PDF

    Prediction of outcome from spatial Protein profiling of triple-negative breast cancers., Ali Foroughi Pour, Te-Chia Wu, Javad Noorbakhsh, Jan Martinek, Santhosh Sivajothi, Paul Robson, Karolina Palucka, and Jeffrey Chuang

    PDF

    Prediction of outcome from spatial Protein profiling of triple-negative breast cancers., Ali Foroughi Pour, Te-Chia Wu, Javad Noorbakhsh, Jan Martinek, Santhosh Sivajothi, Paul Robson, Karolina Palucka, and Jeffrey Chuang

    PDF

    Prevalence of, Edison Liu, Margaret Antonio, Tracy Nance, and Francesca Menghi

    PDF

    Prevalence of, Edison Liu, Margaret Antonio, Tracy Nance, and Francesca Menghi

    PDF

    Prevention of transgene silencing during human pluripotent stem cell differentiation., Takeshi Uenaka, Alan Napole, Aninda Dibya Saha, Duo Sun, Angelina Singavarapu, Elizabeth Calzada, Jiahui Chen, Lena Erlebach, Amanda McQuade, Daniel M Ramos, Alessandra Rigamonti, Lisa Salazar, Avi J Samelson, Kamilla Sedov, Natalie J Welsh, Katleen Wild, Qianxin Wu, Ernest Arenas, Andrew R Bassett, Martin Kampmann, Deborah Kronenberg-Versteeg, Florian T Merkle, Birgitt Schüle, Leslie M Thompson, William C Skarnes, Michael E Ward, and Marius Wernig

    PDF

    Prevention of transgene silencing during human pluripotent stem cell differentiation., Takeshi Uenaka, Alan Napole, Aninda Dibya Saha, Duo Sun, Angelina Singavarapu, Elizabeth Calzada, Jiahui Chen, Lena Erlebach, Amanda McQuade, Daniel M Ramos, Alessandra Rigamonti, Lisa Salazar, Avi J Samelson, Kamilla Sedov, Natalie J Welsh, Katleen Wild, Qianxin Wu, Ernest Arenas, Andrew R Bassett, Martin Kampmann, Deborah Kronenberg-Versteeg, Florian T Merkle, Birgitt Schüle, Leslie M Thompson, William C Skarnes, Michael E Ward, and Marius Wernig

    PDF

    Primate gut microbiota induce evolutionarily salient changes in mouse neurodevelopment., Alex R DeCasien, Jacob E Aronoff, Elizabeth K Mallott, Sahana Kuthyar, Sriram Chitta, Brian T Layden, Maria L Savo Sardaro, Stanton Gray, Lawrence E Williams, Emma R Liechty, Hyo M Lee, Won Lee, James P Curley, Christopher W Kuzawa, and Katherine R Amato

    PDF

    Rapid Changes in Cholinergic Signaling, Myelination, and Thyroid Signaling Pathway Gene Expression in Amygdala Subnuclei in Response to Social Status Maintenance and Reorganization., Tyler M Milewski, Won Lee, Köll R Rada, and James P Curley

    PDF

    RareLink: scalable REDCap-based framework for rare disease interoperability linking international registries to FHIR and Phenopackets., Adam S L Graefe, Filip Rehburg, Samer Alkarkoukly, Daniel Danis, Ana Grönke, Miriam R Hübner, Alexander Bartschke, Thomas Debertshäuser, Sophie A I Klopfenstein, Julian Saß, Julia Fleck, Mirko Rehberg, Jana Zschüntzsch, Elisabeth F Nyoungui, Tatiana Kalashnikova, Luis Murguía-Favela, Beata Derfalvi, Nicola A M Wright, Shahida Moosa, Soichi Ogishima, Oliver Semler, Susanna Wiegand, Peter Kühnen, Christopher J Mungall, Melissa A Haendel, Peter N Robinson, Sylvia Thun, and Oya Beyan

    PDF

    Retention of lysosomal acid sphingomyelinase protects from Niemann-Pick Disease., Cameron A Beard, Kyra N Hermanson, Justin M Snider, Aki Hara, Brandon K Dahl, Janet J Allopenna, Marilyn T Marron, Benjamin Newcomb, Benjamin E. Low, Michael V. Wiles, Russell W Jenkins, Lina M Obeid, Yusuf A Hannun, and Ashley J Snider

    PDF

    Rethinking ratio-based normalization towards model-based approaches in heart weight analysis., Manuela A Oestereicher, Patricia da Silva-Buttkus, Valérie Gailus-Durner, Susan Marschall, Helmut Fuchs, IMPC Consortium, Martin Hrabě de Angelis, Elida Schneltzer, and Nadine Spielmann

    PDF

    RNA binding of GAPDH controls transcript stability and protein translation in acute myeloid leukemia., Sama Shamloo, Jeffrey L Schloßhauer, Shashank Tiwari, Kim Denise Fischer, Omar Almolla, Yohana Ghebrechristos, Lisa Kratzenberg, Aathma Merin Bejoy, Ioannis Aifantis, Francesco Boccalatte, Eric Wang, and Jochen Imig

    Link

    Roads and detours for CAR T cell therapy in autoimmune diseases., Jérôme Avouac, Adi Barzel, Delma Caiati, Randall S Davis, Stephen Gottschalk, Ricardo Grieshaber-Bouyer, Xuming Mao, Eline T Luning Prak, Marko Radic, Marc Scherlinger, Yatin Suneja, Aimee Talleur, Amber L Thacker, and Derya Unutmaz

    Link

    Roads and detours for CAR T cell therapy in autoimmune diseases., Jérôme Avouac, Adi Barzel, Delma Caiati, Randall S Davis, Stephen Gottschalk, Ricardo Grieshaber-Bouyer, Xuming Mao, Eline T Luning Prak, Marko Radic, Marc Scherlinger, Yatin Suneja, Aimee Talleur, Amber L Thacker, and Derya Unutmaz

    PDF

    Sex-specific evolutionary programs shape recombination rate evolution in house mice., Lydia K Wooldridge, Micah Pietraho, Peyton DiSiena, Sam Littman, Benjamin Clauss, and Beth L Dumont

    Link

    Sex-specific proteostasis and urothelial responses to senolytic therapy in the aged mouse bladder., Sumiran Kasturi, Arnold M Salazar, Cara C Hardy, Ron Korstanje, and Indira U Mysorekar

    Link

    Sex-specific proteostasis and urothelial responses to senolytic therapy in the aged mouse bladder., Sumiran Kasturi, Arnold M Salazar, Cara C Hardy, Ron Korstanje, and Indira U Mysorekar

    PDF

    Short-term sleep restriction in humans alters diurnal circulating metabolite profiles, including those of microbial origin., Vanessa A Leone, Katya Frazier, Manpreet Kaur, Evan A Chrisler, Ashley M Sidebottom, Ethan Tai, ViLinh Tran, Shuzhao Li, Eugene B Chang, Dean P Jones, Eve Van Cauter, and Erin C Hanlon

    PDF

    Short-term sleep restriction in humans alters diurnal circulating metabolite profiles, including those of microbial origin., Vanessa A Leone, Katya Frazier, Manpreet Kaur, Evan A Chrisler, Ashley M Sidebottom, Ethan Tai, ViLinh Tran, Shuzhao Li, Eugene B Chang, Dean P Jones, Eve Van Cauter, and Erin C Hanlon

    PDF

    Single-cell landscape of sex-specific drivers of Alzheimer's disease., Yiyang Wu, Kyle J Travaglini, Mariano Gabitto, C Dirk Keene, Amy R Dunn, Catherine C Kaczorowski, Philip L De Jager, Vilas Menon, Julie A Schneider, David A Bennett, Logan Dumitrescu, and Timothy J Hohman

    PDF

    Single-cell transcriptomics of the myeloid milieu reveals an angiogenic niche in triple-negative breast cancer., Yechan Choi, Minkyu Shim, Suhn Hyung Kim, Duk Ki Kim, Juhee Jeong, Jinyoung Byeon, Giyong Jang, Ji-Yeon Kim, Paul Robson, Charles Lee, Han-Byoel Lee, and Keehoon Jung

    PDF

    Single-dose administration of therapeutic divalent siRNA targeting MECP2 prevents lethality in an MECP2 duplication mouse model., Vignesh N Hariharan, Ashley Summers, Amy E Clipperton-Allen, Jillian Caiazzi, Samuel R Hildebrand, Daniel O' Reilly, Qi Tang, Zachary Kennedy, Dimas Echeverria, Nicholas McHugh, David Cooper, Jacquelyn Sousa, Chantal Ferguson, Hassan H Fakih, Laurent P. Bogdanik, Monica Coenraads, and Anastasia Khvorova

    PDF

    Single-nucleus transcriptomics, pharmacokinetics, and pharmacodynamics of CDK4/6 and mTOR inhibition in a Phase 0/1 trial of recurrent high-grade glioma., Kevin C Johnson, An-Chi Tien, Jun Jiang, James McNamara, Yu-Wei Chang, Chelsea Montgomery, Anita DeSantis, Leonel Elena-Sanchez, Yoko Fujita, Seongho Kim, Avishay Spitzer, Paul Gabriel, William F Flynn, Elise T Courtois, Amy Hong, Jocelyn Harmon, Yoshie Umemura, Artak Tovmasyan, Jing Li, Shwetal Mehta, Roel G W Verhaak, and Nader Sanai

    PDF

    Somatic deficiency of the human E3 ubiquitin ligase CBL in leukocytes impairs B cell but not T cell development and function., Taja Vatovec, Anna-Lena Neehus, Katherine J L Jackson, Danielle T Avery, Ivan Bagarić, Lucia Erazo, Carlos A Arango-Franco, Masato Ogishi, Syed F Ahmed, Axel Cederholm, Amanda J Russell, Erika Della Mina, Dena Al-Rifai, Rowena Bull, Lori Buetow, Steicy Sobrino, Allison Zhang, Lara Wahlster, Marine Michelet, Nima Parvaneh, Jessica Peel, Federica Barzaghi, Davide Leardini, Quentin Philippot, Francesco Saettini, Jacques Dutrieux, Benedicte de Muylder, Francesca Vendemini, Francesco Baccelli, Albert Catala, Eleonora Gambineri, Marinella Veltroni, Vignesh Pandiarajan, Yurena Aguilar, Filomeen Haerynck, Michael Elliott, Stuart Turville, Fabienne Brillot, Taushif Khan, Filippo Consonni, Laureline Berteloot, William A Sewell, Geetha Rao, Laetitia Largeaud, Francesca Conti, Cecile Roullion, Cécile Masson, Francesco Pegoraro, Tianyi Ye, Samantha Joubran, Emily Villalpando, Boris Bessot, Yoann Seeleuthner, Tom Le Voyer, Jérémie Rosain, Hailun Li, Zarah Janda, Edoardo Muratore, Camille Soudée, Eric Delabesse, Claire Goulvestre, Mohammad Shahrooei, Anne Puel, Isabelle André, Christine Bole-Feysot, Laurent Abel, Miriam Erlacher, Vivien Béziat, Chantal Lagresle-Peyrou, Remi Cheynier, Emmanuelle Six, Nico Marr, Marlène Pasquet, Laia Alsina, Christopher C Goodnow, Nils Landegren, Alessandro Aiuti, Peng Zhang, Riccardo Masetti, Danny T Huang, Cindy S Ma, Jean-Laurent Casanova, Vijay G Sankaran, Jacinta Bustamante, Stuart G Tangye, and Jonathan Bohlen

    PDF

    Spoti-find: a novel, open-source void spot assay image analysis tool., Cara M. Statz, Susan Sheehan, Seamus Mawe, Nick Sebasco, Will Ricke, J Matthew Mahoney, and Ron Korstanje

    PDF

    Stimulation of the medial septum diagonal band of broca rescues learning and memory deficits in, Mohamed Ouardouz, Amanda E Hernan, J Matthew Mahoney, and Rodney C Scott

    PDF

    Stimulation of the medial septum diagonal band of broca rescues learning and memory deficits in, Mohamed Ouardouz, Amanda E Hernan, J Matthew Mahoney, and Rodney C Scott

    PDF

    Stromal cell senescence augments haematopoietic cell fitness in clonal haematopoiesis., Jayna J Mistry, Kira Young, Anna Navarro Figueredo, Gibran Edun, Alicia G Aguilar-Navarro, Patricia A Colom Díaz, Maria Telpoukhovskaia, Inés Fernández Maestre, Sheng F Cai, Katharina S Götze, Anastasia N Tikhonova, Ross L Levine, and Jennifer J. Trowbridge

     

    Synaptic dysregulation in a mouse model of GRIN2D developmental and epileptic encephalopathy., JiaJie Teoh, Jane Simko, Chad R Camp, Christine J Liu, Wanqi Wang, Damian J Williams, Liang Ma, Divyalakshmi Soundararajan, Caryn Martin, Noah K Taylor, Ekniel François, Sabrina Petri, Ayla Kanber, Aishwarya Ravichandra, Maria Elena Pero, Francesca Bartolini, Theresa C Swayne, Cathleen Lutz, Aamir Zuberi, Moran Rubinstein, Moran Hausman-Kedem, Hongjie Yuan, Jennifer N Gelinas, Tristan T Sands, Scott Q Harper, Stephen F Traynelis, Christopher D Makinson, and Wayne N Frankel

    PDF

    Systematic benchmarking demonstrates large language models have not reached the diagnostic accuracy of traditional rare-disease decision support tools., Justin T Reese, Leonardo Chimirri, Yasemin Bridges, Daniel Danis, J Harry Caufield, Michael A Gargano, Carlo Kroll, Andrew Schmeder, Fengchen Liu, Kyran Wissink, Julie A McMurry, Adam S L Graefe, Enock Niyonkuru, Daniel R Korn, Elena Casiraghi, Giorgio Valentini, Julius O B Jacobsen, Melissa Haendel, Damian Smedley, Christopher J Mungall, and Peter N Robinson

    PDF

    Targeting Pediatric Glioblastomas by Combining OLIG2 Inhibitor CT-179 with Fractionated Radiation in a Panel of Patient-Derived Orthotopic Xenograft Mouse Models., Holly Lindsay, Yuchen Du, Lin Qi, Huiyuan Zhang, Sibo Zhao, Frank K Braun, Mari Kogiso, Clifford Stephan, Gordon Alton, Gregory Stein, Graham Beaton, Santosh Kesari, Steven Neuhauser, Timothy M Stearns, Jeffrey Chuang, Emily L Jocoy, Carol J Bult, Beverly Teicher, Malcolm A Smith, and Xiao-Nan Li

    PDF

    Targeting Pediatric Glioblastomas by Combining OLIG2 Inhibitor CT-179 with Fractionated Radiation in a Panel of Patient-Derived Orthotopic Xenograft Mouse Models., Holly Lindsay, Yuchen Du, Lin Qi, Huiyuan Zhang, Sibo Zhao, Frank K Braun, Mari Kogiso, Clifford Stephan, Gordon Alton, Gregory Stein, Graham Beaton, Santosh Kesari, Steven Neuhauser, Timothy M Stearns, Jeffrey Chuang, Emily L Jocoy, Carol J Bult, Beverly Teicher, Malcolm A Smith, and Xiao-Nan Li

    PDF

    Telomere-to-telomere genome assembly and a pangenome for the rat., Kai Li, Julia L Ciosek, Sergey Koren, Adam M Phillippy, Yaming Zhu, William A Lauer, Shelise Y Brooks, Gerard G Bouffard, Brandon D Pickett, Beth L Dumont, Melissa L Smith, Theodore S Kalbfleisch, and Peter A Doris

    Link

    Temsirolimus in Patients With Solid Tumors With, Evan Pisick, Michael Rothe, Elizabeth Garrett-Mayer, Gordan Srkalovic, John K Chan, Carmen J Calfa, Charles A Leath, Alissa S Marr, Philip J Gold, Erin K Crane, Justin T Moyers, Kathleen Yost Butler, Anu Gaba, Ramya Thota, Kathleen K Harnden, Olatunji B Alese, Angela Jain, Jens Rueter, Sarah Gill, Thomas J George, Marina Frimer, Fadi Kayali, Pam K Mangat, Dominique C Hinshaw, Abigail Gregory, Gina N Grantham, Susan Halabi, and Richard L Schilsky

    PDF

    Tet2 deficiency promotes IgG1+ B-cell expansion and differentiation blockade through deregulation of the Nfkbia-c-Rel axis, Hussein Ghamlouch, Michaël Degaud, Veronique Della-Valle, Alexandre Eeckhoutte, Marine Armand, Amina Joudat, Camille Decaudin, Pilar M Dominguez, Wojciech Rosikiewicz, Patrycja Pawlikowska, Walaa Darwiche, Enguerran Mouly, Sheng Li, Ari M Melnick, Said Aoufouchi, and Olivier A Bernard

    PDF

    Tet2 modulates ER stress responses related to β-cell death and autoimmunity in diabetes., Jinxiu Rui, Madhav Kothari, Romy Kursawe, Mahsa Nouri Barkestani, Romi Genosar, Pamela Clark, Michael L. Stitzel, and Kevan C Herold

    PDF

    Tet2 modulates ER stress responses related to β-cell death and autoimmunity in diabetes., Jinxiu Rui, Madhav Kothari, Romy Kursawe, Mahsa Nouri Barkestani, Romi Genosar, Pamela Clark, Michael L. Stitzel, and Kevan C Herold

    PDF

    TET CpG sequence-context-specific DNA demethylation shapes progression of IDH-mutant gliomas., Youri Hoogstrate, Santoesha A Ghisai, Levi van Hijfte, Rania Head, Iris de Heer, Marta Padovan, Maurice de Wit, Wies R Vallentgoed, Angelo Dipasquale, Maarten M J Wijnenga, Bas Weenink, Rosa Luning, Sybren L N Maas, Adela Brzobohata, Michael Weller, Tobias Weiss, Maximilian J Mair, Anna S Berghoff, Adelheid Wöhrer, Albert Jeltsch, Johan A F Koekkoek, Hans M Hazelbag, Mathilde C M Kouwenhoven, Yongsoo Kim, Bart A Westerman, Bauke Ylstra, Anneke M Niers, Kevin C Johnson, Frederick S Varn, Roel G W Verhaak, Mustafa Khasraw, Martin J van den Bent, Pieter Wesseling, and Pim J French

    PDF

    TET CpG sequence-context-specific DNA demethylation shapes progression of IDH-mutant gliomas., Youri Hoogstrate, Santoesha A Ghisai, Levi van Hijfte, Rania Head, Iris de Heer, Marta Padovan, Maurice de Wit, Wies R Vallentgoed, Angelo Dipasquale, Maarten M J Wijnenga, Bas Weenink, Rosa Luning, Sybren L N Maas, Adela Brzobohata, Michael Weller, Tobias Weiss, Maximilian J Mair, Anna S Berghoff, Adelheid Wöhrer, Albert Jeltsch, Johan A F Koekkoek, Hans M Hazelbag, Mathilde C M Kouwenhoven, Yongsoo Kim, Bart A Westerman, Bauke Ylstra, Anneke M Niers, Kevin C Johnson, Frederick S Varn, Roel G W Verhaak, Mustafa Khasraw, Martin J van den Bent, Pieter Wesseling, and Pim J French

    PDF

    The ClinGen Syndromic Disorders Gene Curation Expert Panel: Assessing the Clinical Validity of 111 Gene-Disease Relationships., Eleanor Broeren, Vanessa Gitau, Alicia Byrne, Pamela Ajuyah, Marie Balzotti, Jonathan Berg, Krista Bluske, B Monica Bowen, Matthew P Brown, Amanda Buchanan, Brendan Burns, Nicole J Burns, Anjana Chandrasekhar, Aditi Chawla, Jessica Chong, Maya Chopra, Amanda Clause, Marina DiStefano, Stephanie DiTroia, Marwa Elnagheeb, Amanda Girod, Himanshu Goel, Katie Golden-Grant, Thuong Ha, Ada Hamosh, Jennifer Huang, Madeline Hughes, Saumya Jamuar, Sylvia Kam, Akanchha Kesari, Ai Ling Koh, Rhonda Lassiter, Sarah Leigh, Gabrielle Lemire, Jiin Ying Lim, Alka Malhotra, Hannah McCurry, Becky Milewski, Shahida Moosa, Stephen A. Murray, Emma Owens, Emma Palmer, Brooke Palus, Mayher Patel, Revathi Rajkumar, Julie Ratliff, F Lucy Raymond, Bruno Della Ripa Rodrigues Assis, Samin Sajan, Zinayida Schlachetzki, Sarah Schmidt, Zornitza Stark, Samuel Strom, Julie Taylor, Courtney Thaxton, Devon Thrush, Sabrina Toro, Kezang Tshering, Nicole Vasilevsky, Bess Wayburn, Ryan Webb, Anne O'Donnell-Luria, and Alison J Coffey

    PDF

    The DO-KB knowledgebase 2026 update: expanding programmatic and language access., J Allen Baron, Claudia M Sánchez-Beato Johnson, Michael A Schor, Dustin Olley, Lance Nickel, Victor Felix, Susan M. Bello, Carol Greene, Richard Lichenstein, Katharine Bisordi, Rima Koka, Cynthia Bearer, Regina Macatangay, Nischal Ada, Kaitlin Ballenger, Emily Bliss, Lauren Colliver, Grace Dobbins, Harrison Heitzig, Shannan Dixon, Patrick Semesky, Jennifer Garth, Matthew Fairchild, Peter Gaskin, Sarina Zahid, Rachel Castillo, Sarah Edwards, Astrid Widjaja, Yamei Usui, Erin Lynch, Melissa Clarkson, Todd Detwiler, and Lynn M Schriml

    PDF

    The Ecological Genome Project and the Promises of Ecogenomics for Society: Realising a Shared Vision as One Health., Benjamin Capps, Ruth Chadwick, Yann Joly, Claire Lajaunie, Iva Hauptmannova, Susannah Mackenzie, John J Mulvihill, Elizabeth Mumford, Sonja A Rasmussen, Kunal Sanghavi, Donrich W Thaldar, James Yeates, Maud C Quinzin, and Zohar Lederman

    PDF

    The Ecological Genome Project and the Promises of Ecogenomics for Society: Realising a Shared Vision as One Health., Benjamin Capps, Ruth Chadwick, Yann Joly, Claire Lajaunie, Iva Hauptmannova, Susannah Mackenzie, John J Mulvihill, Elizabeth Mumford, Sonja A Rasmussen, Kunal Sanghavi, Donrich W Thaldar, James Yeates, Maud C Quinzin, and Zohar Lederman

    PDF

    The HUGO Clinical Genomics & Genomic Medicine Education Survey: clinicians globally need and want genomic medicine training., Charles Wray, Edward S Tobias, Dhavendra Kumar, Qasim Ayub, Ada Hamosh, Iscia Lopes-Cendes, Luz Berenice Lopez Hernandez, and Sherifa Ahmed Hamed

    PDF

    The mouse Gene Expression Database (GXD): 2026 update., Constance M. Smith, Terry F. Hayamizu, Jacqueline H. Finger, Ingeborg J. McCright, Jingxia Xu, Jeff Campbell, Lori E. Corbani, Jake Emerson, Pete J. Frost, Hongping Liang, Joel E Richardson, Richard M. Baldarelli, and Martin Ringwald

    Link

    The Neuromuscular Junction: A Shared Vulnerability in Aging and Disease., Kathryn R Moss, Fereshteh B Darvishi, Yomna Badawi, Lauren A Fish, Jonathan R Funke, Thomas H Pedersen, Richard Robitaille, William David Arnold, Robert W. Burgess, Stephen D Meriney, Hiroshi Nishimune, and Smita Saxena

     

    The OGT-TFF2 axis mediates intrahepatic crosstalk and MASH pathogenesis., Lei Zhang, Cuijuan Han, Man Mohan Shrestha, Jiamei Le, Wilhelm K Berger, Yiheng Huang, Reina Desrouleaux, Eric Wang, Laszlo Nagy, and Xiaoyong Yang

    PDF

    The past, the present, and the future of preclinical mouse models for Alzheimer's disease and related dementias., Adrian L Oblak, Michael Sasner, Gregory W. Carter, Gareth R Howell, Stacey J Sukoff Rizzo, Karina Leal, Paul R Territo, and Bruce T Lamb

    PDF

    The recombinant zoster vaccine induces trained immunity in monocytes through persistent downregulation of TGFβ., Michael J Johnson, Megan Crotteau, Debashis Ghosh, Thao Vu, Luke Trinity, Radu Marches, Duygu Ucar, Myron J Levin, and Adriana Weinberg

    Link

    The RSNA Lumbar Degenerative Imaging Spine Classification (LumbarDISC) Dataset., Tyler J Richards, Adam E Flanders, Errol Colak, Luciano M Prevedello, Robyn L Ball, Felipe Kitamura, John Mongan, Maryam Vazirabad, Hui-Ming Lin, Anne Kendell, Thanat Kanthawang, Salita Angkurawaranon, Emre Altinmakas, Hakan Dogan, Paulo Eduardo de Aguiar Kuriki, Arjuna Somasundaram, Christopher Rushton, Deniz Bulja, Naida Spahović, Jennifer Sommer, Sirui Jiang, Eduardo Moreno Júdice de Mattos Farina, Eduardo Caminha Nunes, Michael Brassil, Megan McNamara, Johanna Ortiz, Jacob Peoples, Vinson L Uytana, Anthony Kam, Venkata N S Dola, Daniel Murphy, David Vu, Arsany Hakim, Jason F Talbott, Dataset Contributor Group, Dataset Annotator Group, and Competition Data Notebook and Curation Group

    Link

    The RSNA Lumbar Degenerative Imaging Spine Classification (LumbarDISC) Dataset., Tyler J Richards, Adam E Flanders, Errol Colak, Luciano M Prevedello, Robyn L Ball, Felipe Kitamura, John Mongan, Maryam Vazirabad, Hui-Ming Lin, Anne Kendell, Thanat Kanthawang, Salita Angkurawaranon, Emre Altinmakas, Hakan Dogan, Paulo Eduardo de Aguiar Kuriki, Arjuna Somasundaram, Christopher Rushton, Deniz Bulja, Naida Spahović, Jennifer Sommer, Sirui Jiang, Eduardo Moreno Júdice de Mattos Farina, Eduardo Caminha Nunes, Michael Brassil, Megan McNamara, Johanna Ortiz, Jacob Peoples, Vinson L Uytana, Anthony Kam, Venkata N S Dola, Daniel Murphy, David Vu, Arsany Hakim, Jason F Talbott, Dataset Contributor Group, Dataset Annotator Group, and Competition Data Notebook and Curation Group

    Link

    Tissue-restricted secondary TCR engagement drives the transition from stem-like to CD200, Yusuke Takeuchi, Daiya Ohara, Hitomi Watanabe, Yuji Nishimura, Takeshi Iwasaki, Shohei Hori, Hiroshi Kawamoto, Hiroki Kato, Gen Kondoh, Akio Morinobu, Tsuneyo Mimori, and Keiji Hirota

    PDF

    Towards clinical translation of nanomedicines: Formulation scale-up and model systems., Owen M Kelly, Andrew R Hanna, Addison K Byrne, Jonathan A Green, Iuri Viotti Perisse, Kevin D Wells, Stephen A. Murray, Jie Xu, Y Eugene Chen, Irina A Polejaeva, Alice F Tarantal, David Issadore, and Alexandra S Piotrowski-Daspit

    PDF

    Trans-regulation of heterochromatin underlies genetic variation in 3D genome contacts in mouse embryonic stem cells., Haley J Fortin, Anna Z Struba, Arad Bustan, and Christopher L. Baker

    PDF

    Understanding the contribution of toxicant exposures to Alzheimer's disease and related dementias., Gareth R Howell, Paul R Territo, David Aylor, and Lee E Goldstein

     

    Under the lens: Taking a close look at the NIH and FDA declarations on animal-based research., Edison Liu

    PDF

    Vascular contribution to cognitive impairment and dementia (VCID): proceedings of 2025 workshop of the Jackson Laboratory., Mehwish Anwer, Tetiana Poliakova, Ricardo D'Oliveira Albanus, Mohammad Iqbal H Bhuiyan, Adam M Brickman, Soumilee Chaudhuri, Leah Cuddy, Maxwell Eisenbaum, Kate Foley, Douglas B Gould, Catherine Hall, Costantino Iadecola, Olivia J Marola, Christopher M Norris, Alaina M Reagan, Julie Schneider, Donna Wilcock, Isabella Xu, Andrew Yang, Gareth R Howell, and Cheryl L Wellington

    PDF

    Vascular contribution to cognitive impairment and dementia (VCID): proceedings of 2025 workshop of the Jackson Laboratory., Mehwish Anwer, Tetiana Poliakova, Ricardo D'Oliveira Albanus, Mohammad Iqbal H Bhuiyan, Adam M Brickman, Soumilee Chaudhuri, Leah Cuddy, Maxwell Eisenbaum, Kate Foley, Douglas B Gould, Catherine Hall, Costantino Iadecola, Olivia J Marola, Christopher M Norris, Alaina M Reagan, Julie Schneider, Donna Wilcock, Isabella Xu, Andrew Yang, Gareth R Howell, and Cheryl L Wellington

    PDF

    Views and experiences regarding workplace genetic testing: findings from a national survey of U.S. employees., Drew Blasco, Sarah McCain, Subhamoy Pal, Wendy R Uhlmann, Rebecca Ferber, Kunal Sanghavi, Elizabeth Charnysh, Anya E R Prince, Charles Lee, J Scott Roberts, and the INSIGHT @ Work Consortium

    PDF

    Views and experiences regarding workplace genetic testing: findings from a national survey of U.S. employees., Drew Blasco, Sarah McCain, Subhamoy Pal, Wendy R Uhlmann, Rebecca Ferber, Kunal Sanghavi, Elizabeth Charnysh, Anya E R Prince, Charles Lee, J Scott Roberts, and INSIGHT @ Work Consortium

    PDF

    Visual detection of seizures in mice using supervised machine learning., Gautam S Sabnis, Leinani Hession, J Matthew Mahoney, Arie Mobley, Marina Santos, Brian Q Geuther, and Vivek Kumar

    PDF

    Where Can We Share the Impactful Work of Applied, Practicing Statisticians?, Emily Griffith, Michiko Wolcott, Robyn L Ball, and Julia Sharp

    PDF

    Whole-genome sequencing reveals individual and cohort level insights into chromosome 9p syndromes., Yingxi Wang, Eleanor I Sams, Rachel Slaugh, Sandra Crocker, Emily Cordova Hurtado, Sophia Tracy, Ying-Chen Claire Hou, Christopher Markovic, Kostandin Valle, Victoria Tate, Khadija Belhassan, Elizabeth Appelbaum, Titilope Akinwe, Rodrigo T Starosta, Yang Cao, Amber Neilson, Yu Liu, Nathaniel Jensen, Reza Ghasemi, Tina Lindsay, Juana Manuel, Sophia Couteranis, Milinn Kremitzki, Jack Ustanik, Thomas Antonacci, Jeffrey K Ng, Andrew Emory, Laura Metz, Tracie DeLuca, Katherine N Lyons, Toni Sinnwell, Brianne Thomeczek, Kymme Wang, Nick Sisneros, Megha Muraleedharan, Anantha Kethireddy, Marco Corbo, Harsha Gowda, Katherine A King, Christina A Gurnett, Susan K Dutcher, Catherine Gooch, Yang E Li, Matthew W Mitchell, Kevin A Peterson, Amjad Horani, Jill A Rosenfeld, Weimin Bi, Pawel Stankiewicz, Hsiao-Tuan Chao, Jennifer E Posey, Christopher M Grochowski, Zain Dardas, Erik G Puffenberger, Christopher E Pearson, Frank Kooy, Dale Annear, A Micheil Innes, Michael Heinz, Richard Head, Robert Fulton, Stephan Toutain, Lucinda Antonacci-Fulton, Xiaoxia Cui, Robi D Mitra, F Sessions Cole, Julie Neidich, Patricia I Dickson, Jeffrey Milbrandt, and Tychele N Turner

    PDF

    Worldwide Innovative Network Consortium: Building a Common Global Cancer Database., Farhood Farahnak, Wafik S El-Deiry, Yves A Lussier, Razelle Kurzrock, Shai Magidi, Catherine Bresson, Shirin A Enger, Jia Liu, Jair Bar, Jeremy L Warner, Tobias Meissner, Eitan Rubin, Jens Rueter, Himabindu Gaddipati, Mandar Kulkarni, Zhen Chen, Sewanti Limaye, Rachel Elsey, Brenda M Rubenstein, Anthony M Joshua, Humaid O Al-Shamsi, Khaled M Musallam, Fanny Wunder, Jacques Raynaud, Guy Berchem, Manon Gantenbein, Amal Al Omari, Said Dermime, Hikmat Abdel-Razeq, Pierre Saintigny, Andrés Cervantes, Roger R Reddel, Adel T Aref, Juan Martin-Liberal, Conxi Lázaro, David Cordero Romera, Marina Sekacheva, Raanan Berger, C S Pramesh, Ioana Berindan-Neagoe, Eugenia Girda, Alejandro Piris-Gimenez, Carol J Farhangfar, Mohammed E Salem, Rodrigo Dienstmann, Ramon Salazar, Naftali Z Frankel, Zachary Batist, Yuri Quintana, and Gerald Batist

    PDF

    Young KRAB-zinc finger gene clusters are highly dynamic incubators of ERV-driven genetic heterogeneity in mice., Melania Bruno, Sharaf M Farhana, Apratim Mitra, Kevin Costello, Dawn E Watkins-Chow, Glennis A Logsdon, Craig W Gambogi, Beth L Dumont, Ben E Black, Thomas M Keane, Anne C Ferguson-Smith, Ryan K Dale, and Todd S Macfarlan

 
 
 

Search

Advanced Search

  • Notify me via email or RSS

Browse

  • Collections
  • Disciplines
  • Authors

Links

  • The Joan Staats Library
  • The Jackson Laboratory
  • JAX Asset Request Form
 
Elsevier - Digital Commons

Home | About | FAQ | My Account | Accessibility Statement

Privacy Copyright